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Journal articles on the topic 'Perindopril erbumine'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Korennova, O. Yu, I. V. Druk, E. A. Turusheva, et al. "Fixed combinations of perindopril and indapamide in hypertensive high-risk patients: antihypertensive efficacy." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 23, no. 3 (2017): 253–59. http://dx.doi.org/10.18705/1607-419x-2017-23-3-253-259.

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Objective.The aim of the study was to compare the antihypertensive efficacy of fixed combinations of perindopril and indapamide in patients with arterial hypertension (HTN) and high cardiovascular risk.Design and methods.We included 65 patients with 1–2 degree of HTN who had not taken the studied drugs before: either perindopril arginine / indapamide 10 mg + 2,5 mg, n = 35), or indapamide / perindopril erbumine K 2,5 mg + 8 mg, n = 30). Clinical efficacy of antihypertensive therapy was evaluated at three different time points. We assessed objective clinical status, blood biochemistry, office b

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2

Rupali, Tambe* Vishakha Toradmal Megha Kirve Tanaya Wakchaure Kavita Gaikwad Ekta Chouthe Snehal Shingne Akshay Bhujbal. "RP-HPLC Method Development and Validation for The Determination of Active Ingredients in Pharmaceuticals." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 3013–29. https://doi.org/10.5281/zenodo.15105797.

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A rapid, accurate, and precise RP-HPLC method was developed for the simultaneous estimation of Indapamide, Amlodipine besylate, and Perindopril erbumine in a combined dosage form. The method utilized a Waters HPLC system with Empower2 software, a UV detector, and a BDS Hypersil C18 column (4.6 × 150 mm, 5 µm). The mobile phase consisted of phosphate buffer (pH 3.0) and acetonitrile (40:60) at a flow rate of 1 mL/min, with detection at 235 nm. The retention times for Indapamide, Amlodipine besylate, and Perindopril erbumine were 2.54, 3.65, and 4.14 minutes, respectively. Assay stud

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3

Pattan, S. R., A. C. Patni, R. A. Mali, et al. "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF PERINDOPRIL ERBUMINE AND AMLODIPINE BESYLATE IN BULK AND TABLET DOSAGE FORM BY HPLC." INDIAN DRUGS 50, no. 05 (2013): 32–35. http://dx.doi.org/10.53879/id.50.05.p0032.

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The objective of this present work was to develop and validate analytical method for quantitative determination of perindopril erbumine and amlodipine besylate in bulk as well as in tablet formulation. The chromatographic separation of the two drugs was achieved on a Varian Microsorb-MV 100-5 C18 column (150×4.6mm, 10 μm). The mobile phase constituted of acetonitrile: buffer (65:35) and pH adjusted to 2.6 with ortho- phosphoric Acid was delivered at the flow rate 1mL/min. Detection was performed at 210 nm. Separation was completed within 6 min calibration curves were linear with correlation co

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4

Pattan, S. R., A. C. Patni, R. A. Mali, et al. "ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF PERINDOPRIL ERBUMINE AND AMLODIPINE BESYLATE IN BULK AND TABLET DOSAGE FORM BY HPLC." INDIAN DRUGS 50, no. 05 (2013): 32–35. http://dx.doi.org/10.53879/id.50.05.p0032.

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The objective of this present work was to develop and validate analytical method for quantitative determination of perindopril erbumine and amlodipine besylate in bulk as well as in tablet formulation. The chromatographic separation of the two drugs was achieved on a Varian Microsorb-MV 100-5 C18 column (150×4.6mm, 10 μm). The mobile phase constituted of acetonitrile: buffer (65:35) and pH adjusted to 2.6 with ortho- phosphoric Acid was delivered at the flow rate 1mL/min. Detection was performed at 210 nm. Separation was completed within 6 min calibration curves were linear with correlation co

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5

Valentin, Ion, Imre Silvia, Cârje Anca Gabriela, and Muntean Daniela Lucia. "Analytical Performance of an HPLC and CZE Methods for the Analysis and Separation of Perindopril Erbumine and Indapamide." Acta Medica Marisiensis 61, no. 4 (2015): 324–27. http://dx.doi.org/10.1515/amma-2015-0073.

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AbstractIntroduction: Perindopril, as an angiotensin converting enzyme inhibitor and indapamide, as a thiazide like diuretic, can be administrated together for the treatment of high blood preasure and other cardiovascular diseases. The aim of this study was to develop two simple and reliable separation methods for perindopril and indapamide by high performance liquid chromatography and capillary zone electrophoresis in order to evaluate their behaviour under separation conditions, for simultaneous separation.Materials and methods: Standard solutions of perindopril erbumine and indapamide in pr

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6

Krishnan, Kiran, and Kathiresan Krishnasamy. "Evaluation of anaphylactic reaction as an adverse event for perindopril erbumine tablets." International Current Pharmaceutical Journal 3, no. 4 (2014): 254–58. http://dx.doi.org/10.3329/icpj.v3i4.18265.

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Perindopril erbumine is a tert-butylamine salt of perindopril used in the treatment of stable coronary artery disease and hypertension. The present study was aimed to evaluate the anaphylactic reaction as an adverse event for perindopril erbumine tablets. Electronic extraction of data from the safety database for this report includes all cases of anaphylactic reaction where perindopril was a primary or co-suspect drug. The study result have shown that there were overall 205 case reports for perindopril in the database, of which 200 cases were assessed as (potentially) perindopril and 05 were a

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7

El-Gizawy, Samia M., Osama H. Abdelmageed, Sayed M. Derayea, Mahmoud A. Omar, and Ahmed M. Abdel-Megied. "Chiral separation of perindopril erbumine enantiomers using high performance liquid chromatography and capillary electrophoresis." Anal. Methods 6, no. 3 (2014): 825–30. http://dx.doi.org/10.1039/c3ay42056f.

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Two separation methods were developed for the determination of S- and R-perindopril tert-butylamine (erbumine salt) (PER): high performance liquid chromatography (HPLC) and capillary electrophoresis (CE).

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8

Jain, P. S., P. R. Badreshiya, S. S. Chalikwar, A. A. Todarwal, and S. J. Surana. "Validation of a dissolution method with RP-HPLC analysis for Perindopril erbumine and Indapamide combination tablet." Chemical Industry and Chemical Engineering Quarterly 18, no. 1 (2012): 19–25. http://dx.doi.org/10.2298/ciceq110628042j.

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A Dissolution method with high performance liquid chromatography (HPLC) analysis was validated for perindopril erbumine and indapamide in combination tablet formulation. The method was validated to meet requirements for a global regulatory filing and this validation included specificity, linearity, accuracy, precision, range, robustness and solution stability studies. The dissolution method, which uses USP apparatus 1 with basket rotating at 100 rpm, 1000 ml of phosphate buffer pH 6.8 as the dissolution medium, and reversed-phased HPLC was carried out at 50?C on a 4.6mm?250mm 5?m cyano column

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9

Remko, Milan. "Molecular structure and stability of perindopril erbumine and perindopril l-arginine complexes." European Journal of Medicinal Chemistry 44, no. 1 (2009): 101–8. http://dx.doi.org/10.1016/j.ejmech.2008.03.012.

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10

André, Vânia, M. Teresa Duarte, Luís Cunha-Silva, and Pedro Paulo Santos. "Alternative crystal forms of the antihypertensive perindopril erbumine." Acta Crystallographica Section A Foundations of Crystallography 66, a1 (2010): s220. http://dx.doi.org/10.1107/s0108767310095012.

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11

Remko, M., J. Bojarska, P. Ježko, L. Sieroń, A. Olczak, and W. Maniukiewicz. "Crystal and molecular structure of perindopril erbumine salt." Journal of Molecular Structure 997, no. 1-3 (2011): 103–9. http://dx.doi.org/10.1016/j.molstruc.2011.05.005.

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12

Unnisa, A., K. V. G. Raju, K. Balaji, A. N. Jyothi, and T. S. Kumar. "New Spectrophotometric Methods for Estimation of Perindopril Erbumine in Bulk and Pharmaceutical Formulations." Journal of Scientific Research 6, no. 2 (2014): 319–27. http://dx.doi.org/10.3329/jsr.v6i2.16106.

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Three rapid, simple, inexpensive, precise, and accurate spectrophotometric procedures were developed for the determination of Perindopril erbumine (PPE) using cobalt-thiocyanate, citric acid and 2,3- dichloro-5,6-dicyano benzoquinone in bulk sample and in dosage forms. The procedures are based on the coordination complex of the drug (electron donor) and the chromogenic reagents used. The colored products are extracted into non aqueous solvents and measured spectrophotometrically at the optimum ?maxfor each complex. Regression analysis of Beer-Lambert plots showed good correlation in the concen

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13

T., Manikya Sastry, and Rama Krishna K. "Extraction-spectrophotometric determination of an ACE inhibitor with naphthol blue-black in formulations." Journal of Indian Chemical Society Vol. 97, No. 9b, Sep 2020 (2020): 1614–19. https://doi.org/10.5281/zenodo.5665308.

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Department of Chemistry, Gayatri Vidya Parishad College of Engineering (Autonomous), Madhurawada, Visakhapatnam-530 048, Andhra Pradesh, India Department of Chemistry, Institute of Science, GITAM (Deemed to be University), Visakhapatnam-530 045, Andhra Pradesh, India <em>E-mail:</em> tmsastry@yahoo.com <em>Manuscript received online 02 July 2020, accepted 22 August 2020</em> A new analytical method has been proposed for the assay and validation of ACE inhibitors in formulations. A bioactive compound, perindopril erbumine (PPE), is selected for its assay in bulk and pharmaceutical formulat

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14

Nazmus, Saqueeb. "MARKET RESEARCH ON POPULAR ANTIHYPERTENSIVE DRUGS." DIU Journal of Health and Life Sciences 2, no. 01 & 02 (2024): 39–43. http://dx.doi.org/10.36481/diujhls.v01i1.5f6ak424.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate),Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazidine Hydrochloride), Ramace (Generic

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Saqueeb, Nazmus. "Market Research On Popular Antihypertensive Drugs." DIU Journal of Allied Health Sciences 2, no. 01 & 02 (2024): 39–43. https://doi.org/10.36481/diujahs.v01i1.5f6ak424.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate),Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazidine Hydrochloride), Ramace (Generic

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16

Setiawati, Effi, Siti Deniati, Danang Yunaidi, et al. "Bioequivalence study of two perindopril erbumine tablet formulations in healthy volunteers." Arzneimittelforschung 61, no. 04 (2011): 234–38. http://dx.doi.org/10.1055/s-0031-1296193.

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17

Nazmus, Saqueeb and Shakil Ahmed. "Market research on Popular Antihypertensive Drugs." DIU Journal of Health and Life Sciences 2, no. 1 & 2 (2015): 39–43. https://doi.org/10.5281/zenodo.11076990.

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Market research is an organized effort to gather information about target markets or customers. The purpose of market research on antihypertensive drugs is to identify the most popular antihypertensive drugs. For this purpose, Different hospitals were visited and 100 prescriptions for antihypertensive patients were collected. The result depicts that Betaloc (Generic name: Metoprolol tartrate), Diretic DS (Generic name: Frusemideand Spironolactone), Carvista (Generic name: Carvedilol), Nidocard(Generic name: nitroglycerin), Metacard MR (Generic name: Trimetazi

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18

Siridevi, Mounica P., Kumar T. Hemant, Rao Y. Srinivasa, and Rao K. Varaprasad. "Simultaneous Spectrophotometric Estimation of amlodipine besylate and Perindopril Erbumine in tablet Formulation." Research Journal of Pharmacy and Technology 12, no. 12 (2019): 6101. http://dx.doi.org/10.5958/0974-360x.2019.01060.6.

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19

Hussein-Al-Ali, Samer Hasan, Aminu Kura, Mohd Zobir Hussein, and Sharida Fakurazi. "Preparation of chitosan nanoparticles as a drug delivery system for perindopril erbumine." Polymer Composites 39, no. 2 (2016): 544–52. http://dx.doi.org/10.1002/pc.23967.

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20

Vehovec, Tanja, Andrej Gartner, Odon Planinšek, and Aleš Obreza. "Influence of different types of commercially available microcrystalline cellulose on degradation of perindopril erbumine and enalapril maleate in binary mixtures / Vpliv različnih tipov komercialno dostopne mikrokristalne celuloze na razpad erbuminijevega perindoprilata in enalaprilijevega maleata v binarnih zmeseh." Acta Pharmaceutica 62, no. 4 (2012): 515–28. http://dx.doi.org/10.2478/v10007-012-0039-5.

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Influence of some commercially available types of microcrystalline cellulose (MCC) on the stability of certain active pharmaceutical ingredients (APIs), when in contact, has been investigated. Two structurally similar APIs, perindopril erbumine (PER) and enalapril maleate (EM), both well-known angiotensin-converting enzyme inhibitors were used. The main properties of an MCC that could determine the stability for each API were measured and correlated to the stability of these two APIs in binary mixtures. The stability of these APIs differed when in contact with different types of MCC. The domin

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21

K. Chatap, Vivekanand, Abhijit M. Karale, Pramod Wagh, and Prashant K. Deshmukh. "Fabrication of Specially Designed Novel Mould for Casting of Perindopril Erbumine Mouth Dissolving Film." Advances in Pharmacology and Pharmacy 1, no. 2 (2013): 58–67. http://dx.doi.org/10.13189/app.2013.010203.

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22

Dorniani, Dena, Aminu Umar Kura, Mohd Zobir Bin Hussein, Sharida Fakurazi, Abdul Halim Shaari, and Zalinah Ahmad. "Controlled-release formulation of perindopril erbumine loaded PEG-coated magnetite nanoparticles for biomedical applications." Journal of Materials Science 49, no. 24 (2014): 8487–97. http://dx.doi.org/10.1007/s10853-014-8559-7.

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23

Rahman, Nafisur, Nishat Anwar, and Mohammad Kashif. "Optimized and Validated Initial-Rate Method for the Determination of Perindopril Erbumine in Tablets." CHEMICAL & PHARMACEUTICAL BULLETIN 54, no. 1 (2006): 33–36. http://dx.doi.org/10.1248/cpb.54.33.

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24

Rahman, Nafisur, and Habibur Rahman. "Quantitative analysis of perindopril erbumine in pharmaceutical preparations by spectrophotometry via ternary complex formation with Zn(II) and eosin and charge transfer complexation with iodine." Spectroscopy 25, no. 2 (2011): 123–36. http://dx.doi.org/10.1155/2011/106936.

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Two simple, sensitive and accurate spectrophotometric methods have been developed for the analysis of perindopril in pharmaceutical preparations. Method A is based on the formation of ternary complex between zinc(II), eosin and the perindopril, which is extractable with chloroform. The absorption spectrum exhibits a band peaking at 510 nm. Method B is based on the interaction of drug with iodine in dichloromethane resulting in the formation of charge transfer complex which absorbs maximally at 365 nm. Beer's law is obeyed in the concentration range 10–200 μg/ml and 10–180 μg/ml with molar abso

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25

Rahman, Nafisur, Habibur Rahman, and Sk Manirul Haque. "Kinetic spectrophotometric method for the determination of perindopril erbumine in pure and commercial dosage forms." Arabian Journal of Chemistry 10 (February 2017): S831—S838. http://dx.doi.org/10.1016/j.arabjc.2012.12.017.

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26

Thuttagunta, Manikya Sastry, and Ramakrishna Karripeddi. "Analytical method for the assay of Perindopril Erbumine in formulations by ion association complex formation using Tropaeolin OOO (TPOOO)." Journal of Indian Chemical Society Vol. 96, Dec 2019 (2019): 1539–44. https://doi.org/10.5281/zenodo.5639236.

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Department of Chemistry, Gayatri Vidya Parishad College of Engineering (Autonomous), Madhrawada, Visakhapatnam-530 047, Andhra Pradesh, India <em>E-mail:</em> tmsastry@yahoo.com Chemistry department, Institute of Science, Technolgy and Management, GITAM (Deemed to be University), Visakhapatnam-530 045, Andhra Pradesh, India <em>Manuscript received online 24 April 2019, revised 09 December 2019, accepted 10 December 2019</em> A novel, inexpensive and responsive analytical technique was developed for the assay and validation of Perindopril Erbumine (PPE) in dosage forms. The procedure involves t

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27

Dugga, H. H. T., R. Peraman, and D. Nayakanti. "Stability-Indicating RP-HPLC Method for the Quantitative Analysis of Perindopril Erbumine in Tablet Dosage Form." Journal of Chromatographic Science 52, no. 4 (2013): 315–20. http://dx.doi.org/10.1093/chromsci/bmt031.

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28

Nagalakshmi, Chatragadda. "Determination of Angiotensin-Converting Enzyme Inhibitor, Perindopril Erbumine, in Bulk and Tablet Dosage Form with HPLC." American Chemical Science Journal 2, no. 4 (2012): 161–76. http://dx.doi.org/10.9734/acsj/2012/2045.

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29

Fael, Hanan, and Amir Al-Haj Sakur. "Novel Spectrofluorimetric Method for the Determination of Perindopril Erbumine Based on Fluorescence Quenching of Rhodamine B." Journal of Fluorescence 25, no. 6 (2015): 1577–84. http://dx.doi.org/10.1007/s10895-015-1666-2.

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30

Luu, Emmy, Kevin B. Ita, Matthew J. Morra, and Inna E. Popova. "The Influence of Microneedles on the Percutaneous Penetration of Selected Antihypertensive Agents: Diltiazem Hydrochloride and Perindopril Erbumine." Current Drug Delivery 15, no. 10 (2018): 1449–58. http://dx.doi.org/10.2174/1567201815666180730125941.

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31

RAHMAN, NAFISUR, HABIBUR RAHMAN, and ASMA KHATOON. "DEVELOPMENT OF SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF PERINDOPRIL ERBUMINE IN PHARMACEUTICAL FORMULATIONS USING 2, 4 DINITROFLUOROBENZENE." Journal of the Chilean Chemical Society 57, no. 2 (2012): 1069–73. http://dx.doi.org/10.4067/s0717-97072012000200002.

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32

Fael, Hanan, and Amir Al-Haj Sakur. "Novel Spectrofluorimetric Method for the Determination of Perindopril Erbumine Based on Charge Transfer Reaction with 7-Hydroxycoumarin." Journal of Fluorescence 25, no. 4 (2015): 811–18. http://dx.doi.org/10.1007/s10895-015-1596-z.

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33

Wei, Xian, Yuzhi Wang, Jiali Weng, et al. "Combination of Perindopril Erbumine and Huangqi-Danshen Decoction Protects Against Chronic Kidney Disease via Sirtuin3/Mitochondrial Dynamics Pathway." Evidence-Based Complementary and Alternative Medicine 2022 (May 21, 2022): 1–9. http://dx.doi.org/10.1155/2022/5812105.

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Background. Chronic kidney disease (CKD) is a major public health problem worldwide. Treatment with renin-angiotensin system inhibitors can achieve only partial efficacy on renal function decline and renal fibrosis in CKD patients. Huangqi-Danshen decoction (HDD) is a basic Chinese herbal pair which is commonly used to treat CKD with good efficacy.Objectives. The current study aimed to investigate the effect of perindopril erbumine (PE), an angiotensin-converting enzyme inhibitor, combined with HDD on adenine-induced CKD rat model and explore the possible mechanism from Sirtuin3/mitochondrial

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34

Sakur, Amir, Tamim Chalati, and Hanan Fael. "Selective spectrofluorimetric method for the determination of perindopril erbumine in bulk and tablets through derivatization with dansyl chloride." Journal of Analytical Science and Technology 6, no. 1 (2015): 12. http://dx.doi.org/10.1186/s40543-015-0045-6.

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35

André, Vânia, Luís Cunha-Silva, M. Teresa Duarte та Pedro Paulo Santos. "First Crystal Structures of the Antihypertensive Drug Perindopril Erbumine: A Novel Hydrated Form and Polymorphs α and β". Crystal Growth & Design 11, № 9 (2011): 3703–6. http://dx.doi.org/10.1021/cg200430z.

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Jain, P. S., H. N. Jivani, R. N. Khatal, A. J. Chaudhari, and S. J. Surana. "RP-HPLC Assay Method for Simultaneous Determination of Perindopril Erbumine and Indapamide Combination in Bulk and Tablet Dosage Form." Journal of Pharmaceutical Research 11, no. 3 (2012): 76. http://dx.doi.org/10.18579/jpcrkc/2012/11/3/79355.

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37

Elgawish, Mohamed, Samia Mostafa, and Abdalla Elshanawane. "Quantitative determination of captopril, perindopril erbumine, moexipril hydrochloride, and ramipril in bulk and pharmaceutical preparations by high performance liquid chromatography." Records of Pharmaceutical and Biomedical Sciences 1, no. 1 (2018): 22–32. http://dx.doi.org/10.21608/rpbs.2018.5917.

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38

SUZUKI, Wataru, Kinuyo KATO, Minoru NAKAOKA, et al. "Studies on the Pharmacokinetics of Perindopril Erbumine in Rats. (1): Plasma Level Profile, Distribution, Metabolism and Excretion after Single Oral Administration." Drug Metabolism and Pharmacokinetics 9, no. 2 (1994): 235–46. http://dx.doi.org/10.2133/dmpk.9.235.

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NAKAOKA, Minoru, Hideo HAKUSUI, Yoshitaka JIN, et al. "Studies on the Pharmacokinetics of Perindopril Erbumine in Rats. (2): Blood Level Profile, Distribution, Metabolism and Excretion after Repeated Oral Administration." Drug Metabolism and Pharmacokinetics 9, no. 2 (1994): 247–57. http://dx.doi.org/10.2133/dmpk.9.247.

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40

Simončič, Z., R. Roškar, A. Gartner, K. Kogej, and V. Kmetec. "The use of microcalorimetry and HPLC for the determination of degradation kinetics and thermodynamic parameters of Perindopril Erbumine in aqueous solutions." International Journal of Pharmaceutics 356, no. 1-2 (2008): 200–205. http://dx.doi.org/10.1016/j.ijpharm.2008.01.031.

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41

Badar, Humera, Ruheena Yasmeen, Fathima Qurratul Ayeen, and Juveria Badar. "Method Development and Validation for the Analysis of Perindopril Erbumine and Amlodipine Besylate by RP-HPLC in Pure and Pharmaceutical Dosage Form." Research Journal of Pharmacy and Technology 13, no. 5 (2020): 2163. http://dx.doi.org/10.5958/0974-360x.2020.00389.3.

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42

Ijaz, Hira, Ume Ruqia Tulain, and Junaid Qureshi. "Formulation and in vitro Evaluation of pH-Sensitive Cross-linked Xanthan Gum-Grafted Acrylic Acid Copolymer for Controlled Delivery of Perindopril Erbumine (PE)." Polymer-Plastics Technology and Engineering 57, no. 5 (2017): 459–70. http://dx.doi.org/10.1080/03602559.2017.1320722.

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Noor, Fatima, Asif Mahmood, Nadiah Zafar та ін. "Fabrication of pH-responsive hydrogels of perindopril erbumine using black seed extract and β-cyclodextrin co-polymerized with methacrylic acid and methylene bisacrylamide". Journal of Drug Delivery Science and Technology 88 (жовтень 2023): 104924. http://dx.doi.org/10.1016/j.jddst.2023.104924.

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44

OBERMAN. "H26 A multicenter controlled study of the efficacy safety and dose range of perindopril erbumine with hydrochlorothiazide in hypertension stages 1, 2, and 3." American Journal of Hypertension 10, no. 4 (1997): 83A. http://dx.doi.org/10.1016/s0895-7061(97)88947-9.

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Patel, Kirtan, Usmangani Chhalotiya, Hetaben Kachhiya, Jay Patel, Dimal Shah, and Dhruti Nagda. "Simultaneous quantification of perindopril erbumine, indapamide and amlodipine besylate in newer combination of anti‐hypertensive drugs in pharmaceutical dosage form by thin layer chromatography method." SEPARATION SCIENCE PLUS 3, no. 5 (2020): 175–84. http://dx.doi.org/10.1002/sscp.202000010.

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NEUTEL, J. "Efficacy and safety of perindopril erbumine, an angiotensin converting enzyme inhibitor (ACE-I), in 2269 elderly hypertensive patients: subgroup analysis of a 12-week, open-label, AceonS Community Trial (ACT)." American Journal of Hypertension 15, no. 4 (2002): A41. http://dx.doi.org/10.1016/s0895-7061(02)02373-7.

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WEBER, M. "Effect of perindopril erbumine, an angiotensin converting enzyme inhibitor (ACE-I), on blood pressure in patients with mild to moderate hypertension - a large AceonS Community Trial (ACT) with 8083 patients." American Journal of Hypertension 15, no. 4 (2002): A41. http://dx.doi.org/10.1016/s0895-7061(02)02374-9.

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48

COHN, J. "Efficacy and safety of perindopril erbumine, an angiotensin converting enzyme inhibitor (ACE-I), in 899 hypertensive patients on oral hypoglycemic agents - subgroup analysis of a 12-week, open-label, aceonS Community Trial (ACT)." American Journal of Hypertension 15, no. 4 (2002): A42. http://dx.doi.org/10.1016/s0895-7061(02)02375-0.

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JULIUS, S. "Effect of perindopril erbumine, an angiotensin converting enzyme inhibitor (ACE-I), in the treatment of 1022 African-American patients with mild to moderate hypertension: subgroup analysis of a 12 week, open-label, AceonSCommunity Trial (ACT)." American Journal of Hypertension 15, no. 4 (2002): A40—A41. http://dx.doi.org/10.1016/s0895-7061(02)02372-5.

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Bishop, Andrew. "Abstract P100: Bioavailability of Arginine versus Erbumine Formulations of Perindopril in Healthy Subjects." Hypertension 70, suppl_1 (2017). http://dx.doi.org/10.1161/hyp.70.suppl_1.p100.

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Abstract:

Perindopril is an angiotensin converting-enzyme inhibitor with a proven track record in cardiovascular clinical trials. Traditionally formulated as the t -butyl amine (“erbumine”) salt, perindopril’s arginine salt has been FDA-approved in combination with amlodipine besylate. The arginine salt has the advantage of being more stable at higher temperatures or humidity. To demonstrate bioequivalence (using the standard FDA definition of 90% confidence intervals that are within 80-125% of the values seen with the reference product), the bioavailability of the two perindopril formulations was compa

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