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Journal articles on the topic 'Periodontitis and antibacterial'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Еловикова, Татьяна, Tat'yana Elovicova, Елена Гайсина, Elena Gaysina, Артем Приходкин, and Artem Prihodkin. "USE OF ANTIBACTERIAL DRUGS FOR THE TREATMENT OF AGGRESSIVE PERIODONTITIS." Actual problems in dentistry 15, no. 1 (2019): 10–15. http://dx.doi.org/10.18481/2077-7566-2019-15-1-10-15.

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Background. Aggressive forms of periodontitis are a group of periodontal diseases characterized by rapid development, significant bone loss, few clinical manifestations, weak inflammatory and immune response, a small number of microorganisms, not proportional to the severity of destruction. According to modern ideas about the etiology of aggressive forms of periodontitis, the main reason for their development – the penetration of periodontal tissue Aggregatibacter actinomycetemcomitans. Therefore, aggressive forms of periodontitis may require adjunct antibacterial therapy. Objective ― to

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Lestari, Kartika Dhipta, Edlyn Dwiputri, Geraldi Hartono Kurniawan Tan, et al. "Exploring the Antibacterial Potential of Konjac Glucomannan in Periodontitis: Animal and In Vitro Studies." Medicina 59, no. 10 (2023): 1778. http://dx.doi.org/10.3390/medicina59101778.

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Background and Objectives: Periodontitis is an inflammatory disease in the supporting tissues of the teeth caused by specific microorganisms or groups of microorganisms. P. gingivalis bacterium is the keystone pathogen in periodontitis, so even at low concentrations, it has a considerable influence on the oral community. Antimicrobials and antiplaque agents can be used as adjunctive therapy for periodontitis treatment. Konjac glucomannan (KGM), as a natural polysaccharide, has flavonoid (3,5-diacetyltambulin) and triterpenoids (ambylon) compounds that show antibacterial activity. This research

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3

Mazur, I. P. "The choice of antibacterial drugs in dentistry taking into account the oral microbiome." Oral and General Health 2, no. 2 (2021): 29–35. http://dx.doi.org/10.22141/ogh.2.2.2021.237655.

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The article presents modern data on the features of the oral microbiome and its medical significance when prescribing systemic antibacterial therapy for infectious and inflammatory processes in the oral cavity. The main microbial associations in normal conditions, as well as in diseases of periodontal tissues and apical periodontitis are presented. The use of antibacterial drugs in dentistry is aimed at eliminating the etiological factor of the pathogenic microflora of the oral cavity. The effectiveness of the treatment depends on how well the doctor aware of the main pathogens and microbial a

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Chi, Minghan, Manlin Qi, Lan A, et al. "Novel Bioactive and Therapeutic Dental Polymeric Materials to Inhibit Periodontal Pathogens and Biofilms." International Journal of Molecular Sciences 20, no. 2 (2019): 278. http://dx.doi.org/10.3390/ijms20020278.

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Periodontitis is a common infectious disease characterized by loss of tooth-supporting structures, which eventually leads to tooth loss. The heavy burden of periodontal disease and its negative consequence on the patient’s quality of life indicate a strong need for developing effective therapies. According to the World Health Organization, 10–15% of the global population suffers from severe periodontitis. Advances in understanding the etiology, epidemiology and microbiology of periodontal pocket flora have called for antibacterial therapeutic strategies for periodontitis treatment. Currently,

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Jain, Hansa. "Antibacterial effect of bestatin during periodontitis." Frontiers in Biology 11, no. 5 (2016): 387–90. http://dx.doi.org/10.1007/s11515-016-1418-y.

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Dağlıoğlu, Yeşim, and Mustafa Cihan Yavuz. "Investigation of Antibacterial activities of Pristine Multi-walled Carbon Nanotube Against Periodontitis-Associated Bacteria and Imaging by Transmission Electron Microscopy: An in vitro Study." Hacettepe Journal of Biology and Chemistry 53, no. 3 (2024): 11–19. https://doi.org/10.15671/hjbc.1557104.

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Objective: It is very important to prevent periodontitis, which is a common oral disease all over the world, with the use of non-toxic and strong antibacterial activities. With the rapid development of nanotechnology in recent years, nanomaterials are widely preferred in dentistry due to their biocompatible structure, durability, lightness and low toxicity. The aim of this study is to investigate the antibacterial activity of multi-walled carbon nanotubes (MWCNTs), with their strong antibacterial activity, low toxicity and high biocompatibility, against periodontitis-causing bacteria. Material

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Janardhan, Karthika, and Hiral Parikh. "Comparative Evaluation of Feracrylum and Chlorhexidine in Nonsurgical Periodontal Therapy in Chronic Periodontitis: A Clinicomicrobiological Study." Journal of Pharmacy and Bioallied Sciences 16, Suppl 3 (2024): S2773—S2775. http://dx.doi.org/10.4103/jpbs.jpbs_387_24.

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ABSTRACT Background: One common inflammatory illness that affects periodontal tissues is chronic periodontitis. By lowering inflammation and getting rid of periodontal bacteria, nonsurgical periodontal management is essential for treating chronic periodontitis. The objective of this study was to evaluate the effectiveness of chlorhexidine and feracrylum in nonsurgical periodontal management for persistent periodontitis. Techniques: As part of their periodontal therapy, 50 patients with a diagnosis of chronic periodontitis were randomized into two groups: first got chlorhexidine, while other Fe

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Volkov, A. G., I. A. Paramonova, I. S. Kopetskiy, et al. "Prospects of using ultrasound therapy in combination with preparation possessing antiseptic effect in complex treatment of periodontitis." Medical alphabet, no. 2 (March 30, 2021): 71–74. http://dx.doi.org/10.33667/2078-5631-2021-2-71-74.

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Ultrasound is able to have a multifaceted therapeutic effect in periodontitis. In therapeutic doses, it affects a variety of local tissue reactions, stimulates compensatory, restorative, protective and adaptive mechanisms.Ultrasound in dosages used in clinical practice does not have an independent, direct antibacterial effect. In this regard, in the treatment of periodontitis, where the microbial factor plays an important role, it is advisable to use antiseptic solutions as a contact medium for ultrasonic effects. The study of the comparative effectiveness of low-frequency and high-frequency u

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9

Sari, Dwi Nur Indah, Christiana Cahyani Prihastuti, Restian Febi Andini, Aldina Gusri, Muhammad Hisyam Ghani, and Haidy Lailatun Nabila. "AKTIVITAS ANTIBAKTERI EKSTRAK TANGKAI Begonia multangula Blume TERHADAP PERTUMBUHAN Aggregatibacter actinomycetemcomitans." Medical and Health Journal 3, no. 1 (2023): 28. http://dx.doi.org/10.20884/1.mhj.2023.3.1.8594.

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Periodontitis is the most common dental and oral disease found in society and can cause tooth loss. One of the bacteria that causes periodontitis is Aggregatibacter actinomycetemcomitans. Periodontitis treatment is carried out by mechanical therapy (scaling and root planning) accompanied by chemical therapy (antibiotics and mouthwash). Prolonged use of chemical therapy can cause resistance, impaired taste and discolored teeth. As an alternative, herbal ingredients that have antibacterial properties can be used. Begonia multangula Blume stalks are used in several areas as a medicinal plant and

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Guo, Xiao, Yan Sun, Zheng Wang, et al. "The Preventive Effect of a Magnetic Nanoparticle-Modified Root Canal Sealer on Persistent Apical Periodontitis." International Journal of Molecular Sciences 23, no. 21 (2022): 13137. http://dx.doi.org/10.3390/ijms232113137.

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Persistent apical periodontitis is a critical challenge for endodontists. Developing root canal filling materials with continuous antibacterial effects and tightly sealed root canals are essential strategies to avoid the failure of root canal therapy and prevent persistent apical periodontitis. We modified the EndoREZ root canal sealer with the antibacterial material dimethylaminododecyl methacrylate (DMADDM) and magnetic nanoparticles (MNPs). The mechanical properties of the modified root canal sealer were tested. The biocompatibility of this sealer was verified in vitro and in vivo. Multispe

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Indeswati, Diyatri, Devijanti Rini, Tantiana, et al. "Anti-inflammatory and antibacterial properties of insulin leaves (Tithonia diversifolia) for Periodontitis." World Journal of Advanced Research and Reviews 20, no. 3 (2023): 1587–91. https://doi.org/10.5281/zenodo.12786875.

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<strong>Introduction:</strong> Periodontal disease or disorders can arise from disruption of homeostasis in the periodontal tissue. Ninety percent of people worldwide suffer from periodontal disease, making it the most common dental disease. Periodontitis may increase the rate of mortality and morbidity significantly. Prevention strategies can be carried out with alternative materials. The use of <em>Tithonia diversifolia</em> or insulin leaves has been practiced folklorically by different ethnic groups without scientific evidence, especially for the treatment of conditions rela

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Nawrot-Hadzik, Izabela, Adam Matkowski, Jakub Hadzik, et al. "Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects." Nutrients 13, no. 1 (2021): 165. http://dx.doi.org/10.3390/nu13010165.

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Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. They exhibit antioxidant, anti-inflammatory, cytoprotective, as well as antimicrobial activity. The latter property is important in the prevention and treatment of periodontal diseases. Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting the periodontium. Using non-toxic and efficient natural products such as flava

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Nawrot-Hadzik, Izabela, Adam Matkowski, Jakub Hadzik, et al. "Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects." Nutrients 13, no. 1 (2021): 165. http://dx.doi.org/10.3390/nu13010165.

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Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. They exhibit antioxidant, anti-inflammatory, cytoprotective, as well as antimicrobial activity. The latter property is important in the prevention and treatment of periodontal diseases. Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting the periodontium. Using non-toxic and efficient natural products such as flava

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Sarkisyan, N. G., L. I. Drozdova, D. S. Umarova, D. A. Solovyova, and K. A. Khlystova. "ASSESSED EFFICACY OF POLYOXIDONIUM IN MEDICATED TREATMENT OF MODELLED CHRONIC PERIODONTITIS (EXPERIMENTAL STUDY)." Russian Journal of Immunology 23, no. 1 (2020): 91–96. http://dx.doi.org/10.46235/1028-7221-010-aeo.

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This article highlights current issues on medical treatment of chronic periodontitis. The lack of effective comprehensive approach to treatment of chronic periodontitis requires to seek for new treatment strategies, which will be based on pathogenetic features of disease development. Experimental study with Wistar rat strain was used as a model of chronic periodontitis created by inserting a 12 mm needle into the periodontal space of the lower incisor. More than 30 models of chronic periodontitis were obtained. A method of conservative therapy by using an immunomodulator (polyoxidonium) was pr

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Li, Xue, Manlin Qi, Chunyan Li, et al. "Novel nanoparticles of cerium-doped zeolitic imidazolate frameworks with dual benefits of antibacterial and anti-inflammatory functions against periodontitis." Journal of Materials Chemistry B 7, no. 44 (2019): 6955–71. http://dx.doi.org/10.1039/c9tb01743g.

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Sidelnikova, L., I. Dikova, and S. Zakharova. "Rationale and assessment of the effectiveness of systemic antibiotic therapy of generalized periodontitis in patients with diabetes mellitus." SUCHASNA STOMATOLOHIYA 102, no. 3 (2020): 28. http://dx.doi.org/10.33295/1992-576x-2020-3-28.

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Objective. To evaluate the efficacy of systemic antibiotic therapy with Tsiprolet A in patients with periodontitis generalizovanim and diabetes. Object and Methods. We examined and treated 25 patients with generalized periodontitis I–II degree and IDDM by a single scheme of clinical studies and index, as recommended by WHO. All patients were treated with topical anti-inflammatory antibiotic therapy using paste «Parasept». In the study group (12 pers.) Additionally given Tsiprolet A for systemic antibiotic therapy. Results. Using the drug «Tsiprolet A» complex therapy of generalized periodontit

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&NA;. "Adjunctive antibacterial drug therapy useful in recurrent periodontitis." Drugs & Therapy Perspectives 19, no. 12 (2003): 12–16. http://dx.doi.org/10.2165/00042310-200319120-00005.

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Morozov, Dmitry I., Alexander G. Volkov, Egor E. Olesov, Nataliya Zh Dikopova, and Yulia A. Trefilova. "Study of the influence of different methods of application of Metrogyl Denta gel on the microbiota of periodontal pockets in periodontitis." Russian Journal of Dentistry 25, no. 1 (2021): 42–47. http://dx.doi.org/10.17816/1728-2802-2021-25-1-42-47.

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BACKGROUND: One of the most popular antibacterial drugs used in periodontology is Metrogil Denta gel. In recent years, it is most often prescribed as a means of local antibacterial therapy. However, there is practically no information about the use of Metrogil Denta gel ultraphonophoresis in the treatment of periodontal tissue diseases. Therefore, the development of the Metrogil Denta gel ultraphonophoresis technique and the study of its effectiveness in inflammatory periodontal diseases has significant theoretical and practical interest. AIM: This study aimed to explore the influence of

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Lee, Won-Jin, Eun-Nam Kim, Nguyen Minh Trang, et al. "Ameliorative Effect of Ginsenoside Rg6 in Periodontal Tissue Inflammation and Recovering Damaged Alveolar Bone." Molecules 29, no. 1 (2023): 46. http://dx.doi.org/10.3390/molecules29010046.

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Periodontal disease is a chronic disease with a high prevalence, and in order to secure natural materials to prevent oral diseases, new materials that protect periodontal tissue from inflammation are being sought. Genes were identified using real-time quantitative polymerase chain reaction (RT-qPCR), and proteins were confirmed using Western blot. Dichlorodihydrofluorescein diacetate (DCF-DA) analysis was used, and the antibacterial effects were confirmed through Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) analysis. To confirm this effect in vivo, Spragu

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Minami, Masaaki, Hiroshi Takase, Masayo Taira, and Toshiaki Makino. "In Vitro Effect of the Traditional Medicine Hainosan (Painongsan) on Porphyromonas gingivalis." Medicines 6, no. 2 (2019): 58. http://dx.doi.org/10.3390/medicines6020058.

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Background: Hainosan (Painongsan) is a traditional Japanese and Chinese medicine that is used to treat several purulent diseases, including gingivitis and periodontitis. This formulation contains three crude drug components: The dried immature fruit of Citrus aurantium (Aurantii Fructus Immaturus), the dried root of Paeonia lactiflora (Paeoniae Radix), and the dried root of Platycodon grandiflorum (Platycodi Radix). Here we evaluated the in vitro antibacterial effects of hainosan extract (HNS) and extracts of its three components against Porphyromonas gingivalis, one of the pathogenic bacteria

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Qomariyah, Lailatul, Fransiska Uli Arta Panjaitan, and Rosihan Adhani. "ANTIBACTERIAL EFFECTIVITY OF FLAVONOID FRACTION OF RAMANIA LEAF EXTRACT (Bouea macrophylla Griffith) AGAINST Porphyromonas gingivalis." Dentino : Jurnal Kedokteran Gigi 6, no. 2 (2021): 147. http://dx.doi.org/10.20527/dentino.v6i2.11997.

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Background: Chronic periodontitis is a periodontal disease with 80% of all cases of periodontitis. The major causes are the accumulation of plaque and bacteria. The dominant bacteria in chronic periodontitis is Porphyromonas gingivalis. Treatment of chronic periodontitis can be done by scaling and root planing and supporting therapy by using mouthwash such as Chlorhexidine gluconate 0.2% which is the gold standard in the treatment of periodontal disease. Chlorhexidine gluconate 0.2% has disadvantages so that nowadays research on herbal plants is being done to find alternative medicines that ar

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Qomariyah, Lailatul, and Fransiska Uli Arta Panjaitan. "ANTIBACTERIAL EFFECTIVITY OF FLAVONOID FRACTION OF RAMANIA LEAF EXTRACT (Bouea macrophylla Griffith) AGAINST Porphyromonas gingivalis." Dentino : Jurnal Kedokteran Gigi 6, no. 1 (2021): 72. http://dx.doi.org/10.20527/dentino.v6i1.10644.

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ABSTRACTBackground: Chronic periodontitis is a periodontal disease with 80% of all cases of periodontitis. The major causes are the accumulation of plaque and bacteria. The dominant bacteria in chronic periodontitis is Porphyromonas gingivalis. Treatment of chronic periodontitis can be done by scaling and root planing and supporting therapy by using mouthwash such as Chlorhexidine gluconate 0.2% which is the gold standard in the treatment of periodontal disease. Chlorhexidine gluconate 0.2% has disadvantages so that nowadays research on herbal plants is being done to find alternative medicines

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Andriani, Ika, Ana Medawati, Muhammad Ihza Humanindito, and Maulida Nurhasanah. "The effect of antimicrobial peptide gel RISE-AP12 on decreasing neutrophil and enhancing macrophage in nicotine-periodontitis Wistar rat model." Dental Journal (Majalah Kedokteran Gigi) 55, no. 2 (2022): 93–98. http://dx.doi.org/10.20473/j.djmkg.v55.i2.p93-98.

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Background: Periodontitis, an inflammation that causes alveolar bone destruction, is caused by bacteria and aggravated by nicotine exposure and is therefore a disease that many smokers have. Antibacterial agents are essential for the rejuvenation process in periodontitis treatment; antimicrobial peptide (AMP) gel is a broad-spectrum antibacterial agent that is hardly cause bacteria resistance. Purpose: The objective of this study is to determine the effect of AMP gel administration on neutrophil and macrophage counts on periodontitis regeneration in nicotine-exposed rats. Methods: 24 Wistar ra

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Indeswati Diyatri, Rini Devijanti, Tantiana, et al. "Anti-inflammatory and antibacterial properties of insulin leaves (Tithonia diversifolia) for Periodontitis." World Journal of Advanced Research and Reviews 20, no. 3 (2023): 1587–91. http://dx.doi.org/10.30574/wjarr.2023.20.3.2599.

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Introduction: Periodontal disease or disorders can arise from disruption of homeostasis in the periodontal tissue. Ninety percent of people worldwide suffer from periodontal disease, making it the most common dental disease. Periodontitis may increase the rate of mortality and morbidity significantly. Prevention strategies can be carried out with alternative materials. The use of Tithonia diversifolia or insulin leaves has been practiced folklorically by different ethnic groups without scientific evidence, especially for the treatment of conditions related with pain and inflammation. Methods:

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Syifaul Amrodi Al Birro, Nur Ariska Nugrahani, Nina Runting, and Noor Hafida Widyastuti. "Effect Of Avocado Seed (Persea Americana Mill.) On The Growth Of Bacteria Prevotella Intermedia (In Vitro)." Jurnal EduHealth 14, no. 3 (2023): 1230–35. http://dx.doi.org/10.54209/jurnaleduhealth.v14i3.2543.

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Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by bacteria present in the dental plaque biofilm. Gingivitis and periodontitis are the most common periodontal diseases and are associated with bacteria Prevotella intermedia. Avocado seeds are one way to inhibit this bacteria. the aim of this study is to prove that avocado seed extract (Persea americana Mill.) has an antibacterial effect on bacterial growth Prevotella intermedia. This study was a pure laboratory experimental post-test only control group design. The research sample was divided into 10 groups

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Pham, Thuy Anh Vu, Thao Thi Phuong Tran, and Ngan Thi My Luong. "Antimicrobial Effect of Platelet-Rich Plasma againstPorphyromonas gingivalis." International Journal of Dentistry 2019 (May 13, 2019): 1–6. http://dx.doi.org/10.1155/2019/7329103.

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Aim. The aim of our study was to evaluate whether there was a difference in antimicrobial effect between the PRP of healthy volunteers and that of patients with chronic periodontitis againstP. gingivalis,which was fresh cultured from subgingival plaque.Methods. Subgingival plaque of patients with moderate and severe chronic periodontitis was collected to isolateP. gingivalis. The PRP of four individuals with healthy periodontium and four patients with moderate and severe periodontitis were collected with a specific kit using a two-centrifuge procedure, and then, the antibacterial properties ag

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Aliyani, Sari, Natallia Pranata, and Vinna Kurniawati Sugiaman. "EFEK ANTIBAKTERIAL CUKA SARI APEL DALAM BERBAGAI KONSENTRASI TERHADAP PORPHYROMONAS GINGIVALIS." Jurnal Ilmiah dan Teknologi Kedokteran Gigi 19, no. 1 (2023): 1–7. http://dx.doi.org/10.32509/jitekgi.v19i1.2157.

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Background: periodontal disease is a disease that can affect the supporting tissues of the teeth. The American Academy of Periodontology (AAP) classifies it into two, namely chronic periodontitis and aggressive periodontitis. Periodontitis is usually caused by bacteria, one of which is Porphyromonas gingivalis. One of the ingredients that can be used as mouthwash and has an antibacterial effect is chlorhexidine, but the use of this mouthwash has side effects so people turn to herbal medicines, namely apple cider vinegar which contains phenols, flavonoids, saponins, and alkaloids as antibacteri

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Tobaq, Fritzia R., Henry Y. Mandalas, and Vinna K. Sugiaman. "Efek Antibakteri Ekstrak Kulit Kelengkeng (Dimocarpus Longan L.) terhadap Porphyromonas gingivalis." e-GiGi 12, no. 1 (2023): 60–66. http://dx.doi.org/10.35790/eg.v12i1.48012.

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Abstract: Porphyromonas gingivalis is one of the microorganisms that cause periodontitis. Chlorhexidine is proven to have an antibacterial effect but it can cause side effects inter alia discolored teeth, pain, and xerostomia. Longan peel is a natural product that can act as an antibacterial because of its active compounds such as phenolics, tannins, flavonoids, and triterpenoids. This study aimed to determine the antibacterial effect of longan peel extract on Porphyromonas gingivalis ATCC 33277 by measuring the average diameter of the inhibition zone. This was a laboratory experimental study

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Faria, Gisele, Paulo Nelson-Filho, Aldevina Campos de Freitas, Sada Assed, and Izabel Yoko Ito. "Antibacterial effect of root canal preparation and calcium hydroxide paste (Calen) intracanal dressing in primary teeth with apical periodontitis." Journal of Applied Oral Science 13, no. 4 (2005): 351–55. http://dx.doi.org/10.1590/s1678-77572005000400007.

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The aim of this study was to evaluate the antibacterial action of root canal mechanical preparation using 2.5% sodium hypochlorite as the irrigating solution and a calcium hydroxide paste as the antibacterial intracanal dressing in human primary teeth root canals with pulp necrosis and apical periodontitis by means of microbial culture. A total of 26 root canals of human primary teeth with pulp necrosis and apical periodontitis were used. Samples were collected before, 72h after biomechanical treatment and 72h after removal of the intracanal dressing. Comparison by Wilcoxon test showed that ro

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Popov, A. A., A. G. Volkov, E. E. Olesov, N. Zh Dikopova, and S. A. Zaslavsky. "Comparative microbiological study of methods of using Metrogyl Dent gel in the treatment of periodontitis." Stomatology for All / International Dental review, no. 2021 2 95 (June 2021): 14–17. http://dx.doi.org/10.35556//idr-2021-2(95)14-17.

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Summary The common drug Metrogyl Denta can be used in different ways in the treatment of periodontitis, in particular, in the form of applications or using high-frequency ultrasound. The article is devoted to the study of the effect of various methods of using Metrogyl Dent gel on the microbiota of periodontal pockets in periodontitis. In 40 patients with a diagnosis of moderate periodontitis, the treatment complex included a combined effect of high-frequency ultrasound and an antibacterial preparation of Metrogyl Dent gel (ultraphonophoresis of Metrogil Dent gel) or Metrogil Dent was used as

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Li, Meng, Yanyan Yang, Chen Lin, et al. "Antibacterial Properties of Small-Size Peptide Derived from Penetratin against Oral Streptococci." Materials 14, no. 11 (2021): 2730. http://dx.doi.org/10.3390/ma14112730.

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Periodontitis, an infectious disease originating from dental biofilms that causes the irreversible loss of alveolar bone, is accompanied by gradual biofilm formation and the continuous progression of inflammation. A small peptide derived from penetratin, Arg-Gln-Ile-Arg-Arg-Trp-Trp-Gln-Arg-NH2 (RR9), appears to have antibacterial properties against selected strains associated with periodontitis. The purpose of this research is to assess the antibacterial activity and mechanism of RR9 against the initial oral colonizers Streptococci oralis, Streptococci gordonii, and Streptococci sanguinis and

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Albert and Syifa Ameliya Az-Zahra. "Potensi Antibakteri Ekstrak (Graptophyllum Pictum (L.) Griff) Pada Porphyromonas gingivalis." Jurnal Kedokteran Gigi Terpadu 6, no. 1 (2024): 45–49. http://dx.doi.org/10.25105/jkgt.v6i1.20854.

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Background: The most prevalent bacteria found in periodontitis are the Gram-negative anaerobic stem bacteria Porphyromonas gingivalis. Periodontitis can potentially affect tooth mobility and tooth loss. Plaque control can be achieved using mechanical tools such as toothbrushes and interdental cleaners, which are reinforced by the use of antibacterial remedies as a chemical approach. Purple leaves contain chemical compounds including alkaloids, flavonoids, tannins, tripenoids, saponins, and glycosides. Objective: To determine the effectiveness of purple leaves as an antibacterial inhibitor agai

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Wang, Hui, Lulu Wang, Tian Chao, and Zhonghui Kang. "Analysis of the Therapeutic Effect of Nano-Silver on Periodontitis and Its Influence on Disease Recurrence." Tobacco Regulatory Science 7, no. 5 (2021): 1131–37. http://dx.doi.org/10.18001/trs.7.5.31.

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Periodontitis is a chronic oral inflammatory disease that is difficult to treat and is therefore the subject of clinical research seeking new and effective treatment. Nano-silver has antibacterial and anti-inflammatory effects; however, its application in periodontitis is not well studied. In this study, we show decreases in periodontitis-associated inflammatory cytokines interleukin IL-4, IL-6, IL-8, IL-10, and tumor necrosis factor alpha (TNF-a) (P < 0.05) and in oxidative stress (P < 0.05) under intervention with nano-silver solution. The protein expression of CCL21, heat-shock protei

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Puri-zakhidan, S., R. Gurbanov, and G. Aliyeva. "Treatment of periodontitis with the combination of antibacterial agents." SUCHASNA STOMATOLOHIYA, no. 1 (2019): 38–41. http://dx.doi.org/10.33295/1992-576x-2019-1-38-41.

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Liu, Yaxi, Zhengrong Yin, Hongling Wu, et al. "Antibacterial-osteogenic integrated liquid metal nanomedicine for periodontitis treatment." Cell Biomaterials 1, no. 1 (2025): 100009. https://doi.org/10.1016/j.celbio.2024.100009.

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Bulkina, Natalia, Olga Guseva, Yulia Osipova, et al. "ANALYSIS OF ORAL FLUID ENZYMES ACTIVITY IN PATIENTS WITH PERIODONTITIS UNDERGOING COMPLEX ANTIBIOTIC THERAPY." Archiv Euromedica 10, no. 4 (2020): 167–69. http://dx.doi.org/10.35630/2199-885x/2020/10/4.37.

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Antibacterial therapy is the fundamental point in comprehensive treatment of patients with generalized periodontitis. The choice of an antibacterial drug, in view of its maximum effectiveness, is the key to successful pre-surgical preparation of patients with periodontitis to rapid post-surgery rehabilitation and remission maintenance. Our clinical study aims to analyze the activity of oral fluid enzymes (lactate dehydrogenase (LDH), alkaline phosphatase (ALP)) in patients treated with fluoroquinolones. 60 patients were allocated to groups. Each group had a 7-day course of one from four antibi

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Pavlovich, O. A., L. A. Skorikova, N. P. Bazhenova, and N. V. Lapina. "OPTIMIZATION OF TREATMENT OF DESTRUCTIVE FORMS OF CHRONIC APICAL PERIODONTITIS." Russian Journal of Dentistry 21, no. 2 (2017): 85–89. http://dx.doi.org/10.18821/1728-28022017;21(2):85-89.

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Increase of efficiency of treatment of patients with chronic apical periodontitis is a priority in dentistry. A root canal is a breeding ground for microorganisms. The main reason for unfavourable treatment outcomes of teeth with chronic apical periodontitis is incomplete debridement of the root canal system. Optimizing the treatment of patients with chronic periodontitis with the use of complex drugs galodent No. 4 (clotrimazole, tracert and calcium hydroxide) is a priority in dentistry. As a result of researches it is established that the antibacterial effect of the temporary investment of c

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Cao, Jiangchuan. "Application of Metal Nanoparticles in the Treatment of Periodontitis." Advances in Engineering Technology Research 13, no. 1 (2025): 1525. https://doi.org/10.56028/aetr.13.1.1525.2025.

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Periodontitis is a common chronic inflammatory disease of the oral cavity, and traditional treatment methods have certain limitations. Metal nano-ions, with their unique physical and chemical properties and biological characteristics, have shown potential in various aspects of the treatment of periodontitis. They possess high antibacterial activity and good biocompatibility, can regulate inflammatory responses, and promote periodontal tissue regeneration. Through local application, systemic application, or in combination with other treatment methods, metal nano-ions have achieved certain clini

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Alshuwairf, Abdulaziz Omar. "Evaluation The Effect of Natural Phytotherapy on Level of Leptin Hormone in Serum With Chronic Periodontitis." Journal of the Academic Forum 8, no. 1 (2024): 1–11. https://doi.org/10.59743/jaf.v8i1.348.

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For a considerable amount of time, periodontal diseases have been recognized as serious health issues in various populations. It refers to a class of locally acquired microbially generated infections that affect the gingiva and the tissues that support the teeth. The two most common kinds of periodontal disorders are gingivitis and chronic periodontitis. It is acknowledged that the primary causative factor for the development and advancement of periodontitis is bacterial plaque. When untreated, chronic periodontitis begins as an inflammatory illness of the gingiva and can eventually spread to

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Nasution, Dewi Lidya Ichwana, Sri Tjahajawati, Ratna Indriyanti, Amaliya Amaliya, Rina Putri Noer Fadilah, and Rahman Mutiara. "Antibacterial test of Peperomia pellucida (L.) Kunth extract against Porphyromonas Gingivalis as a potential herb for periodontitis: a laboratory experiment." Padjadjaran Journal of Dentistry 35, no. 3 (2023): 181. http://dx.doi.org/10.24198/pjd.vol35no3.47856.

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ABSTRACTIntroduction: Periodontitis is a multifactorial inflammatory disease which is generally caused by plaque accumulation. Many studies have shown that Porphyromonas gingivalis (Pg) is the main etiological agent that contributes to chronic periodontitis. Scaling and root planing (SRP) is the gold standard for periodontitis treatment. The use of antibiotics as additional agents accompanying the SRP procedure has limitations that can cause resistance to subgingival periodontal pathogens. Peperomia pellucida (L.) Kunth i.e betel leaf is a natural ingredient that contains anti-inflammatory, an

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Pratiwi, Gracia Yodianvi, Henry Yonatan Mandalas, and Vinna Kurniawati Sugiaman. "<strong>The effect of Indian jujube leaves extract in inhibiting the growth of <em>Porphyromonas gingivalis</em></strong>." Padjadjaran Journal of Dentistry 34, no. 1 (2022): 57. http://dx.doi.org/10.24198/pjd.vol34no1.33007.

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Introduction: Periodontitis is an inflammatory disease that destroys tooth-supporting tissues and is associated with increased risk factors for systemic diseases. The main pathogen of periodontitis is the bacteria P. gingivalis, a Gram-negative, anaerobic, pleomorphic, coccobacillus, non-motile, and saccharolytic. The leaves of Indian jujube (Ziziphus mauritiana Lam.) have the main bioactive compounds such as saponins, tannins, and flavonoids which have antimicrobial activities against pathogenic microorganisms. This study aims to analyse various concentrations of the ethanol extract of Indian

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Norimasa Tsuji, Hideki Yoshimatsu, Ryuhei Kanda, Masataka Hashimoto, and Hiroshi Maeda. "Investigation of the antibacterial effects of hinokitiol on Fusobacterium nucleatum." World Journal of Advanced Research and Reviews 25, no. 3 (2025): 103–8. https://doi.org/10.30574/wjarr.2025.25.3.0607.

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Hinokitiol (HNK), which is known to have stress-relieving properties in living organisms and to show antimicrobial activity against both bacteria and fungi, has been used as a form of aromatherapy in oral care products, such as bath additives, toothpaste, and mouthwash. This study was performed to assess the antibacterial effects of HNK on Fusobacterium nucleatum isolates from patients with periodontitis. F. nucleatum was cultured on Gifu Anaerobic Medium (GAM) for 24 h. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of HNK against F. nucleatum were det

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R Kusugal, Dr Jyotsna, Dr Swati Setty, Dr Pradeep Agnihotri, and Dr Srinath Thakur. "Evaluation of antimicrobial properties of acacia catechu (Khadir): an in-vitro studyEvaluation of antimicrobial properties of acacia catechu (Khadir): an in-vitro study." RGUHS Journal of Dental Sciences 12, no. 2 (2020): 25–30. http://dx.doi.org/10.26715/rjds.12_2_6.

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Context: Acacia catechu has got antimicrobial property. The evaluation of this property against periodontal pathogens may open new doors to treatment modalities of gingivitis and periodontitis. Aims: To evaluate the antimicrobial property of Acacia catechu (Khadir) against periodontal pathogens, Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) in subgingival plaque samples of generalized periodontitis patients. Settings and Design: Prospective, observational, microbiological, in-vitro. Methods and Material: Subgingival plaque samples of generalized periodontitis pat

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Alameer, Murtadha IA, Hayder R. Abdulbaqi, and Dinesh Martin. "Antibacterial effect of green tea against Porphyromonas gingivalis: a literature review." Journal of Baghdad College of Dentistry 36, no. 1 (2024): 70–78. http://dx.doi.org/10.26477/jbcd.v36i1.3592.

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Green tea is regarded as a healthy beverage due to the biological action of polyphenols, specifically catechins. Researchers investigated the inhibitory effects of green tea (Camellia sinensis) plant on both Gram- positive and Gram-negative bacteria. Periodontitis is mainly initiated when dysbiosis of the subgingival microbiome takes place. Porphyromonas gingivalis is one of the key pathogens involved in the initiation and progression of periodontitis when its levels in subgingival biofilm overwhelm the host's immune system. It is the main pathogen that is significantly linked to severe period

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Wankhade, Vikrant Pradip, K. A. Hiwe, and S. C. Atram. "Dental Drug Delivery System used in Periodontitis." Journal of Dental Research and Review 10, no. 4 (2023): 185–93. http://dx.doi.org/10.4103/jdrr.jdrr_12_22.

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Periodontitis, a condition affecting the teeth’s supporting structures, affects people of all ages, ethnicities, races, and genders. There is a well-established link involving microbial infection and the progression of gum diseases and tooth cavities. There are different types of periodontal diseases caused by microbial infection. Aggressive periodontitis can be localized or generalized. Periodontal infection has been successfully treated with antibacterial medicines. The effectiveness of mechanical plaque debridement and regular use of topical and systemic medicines is limited due to a lack o

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Karakov, Karen, Emilia Khachaturyan, Marat Uzdenov, et al. "METHOD FOR TREATING CHRONIC GENERALIZED PERIODONTITIS OF LIGHT AND MEDIUM GRAPES." Actual problems in dentistry 16, no. 2 (2020): 53–58. http://dx.doi.org/10.18481/2077-7566-20-16-2-53-58.

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Subject. The article presents the data of a comparative analysis of the traditional method of treating chronic generalized periodontitis of mild to moderate severity and with the use of periodontal dressings in combination with an antibacterial photodynamic system. The goal is to study the effectiveness of the methodology of complex therapy for the treatment of periodontal diseases using periodontal dressings and antibacterial photodynamic therapy. Methodology. We observed 120 patients with inflammatory periodontal diseases aged 18 to 55 years (men ― 52, women ― 68), who were divid

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Herryawan, Badi Soerachman, and Sarah Andintama Gustimuda Chaeruddin. "COMPARISON OF THE ANTIBACTERIAL EFFECTIVENESS OF RED BETEL EXTRACT WITH BLACK BETEL EXTRACT ON Porphyromonas gingivalis BACTERIA." Journal of Health and Dental Sciences 3, no. 1 (2023): 53–68. http://dx.doi.org/10.54052/jhds.v3n1.p53-68.

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Periodontitis is a chronic inflammatory disease of the tooth-supporting structures of the teeth caused by a group of specific microorganisms in dental plaque. Porphyromonas gingivalis (Pg) is a bacterium that causes periodontitis found in subgingival plaque. Antibacterial agents are needed as additional therapy to complete mechanical treatment, the main therapy for periodontitis treatment. Red betel (Piper crocatum) and black betel (Piper betle L. var nigra) are herbal plants with active compounds of flavonoids, alkaloids, saponins, tannins, phenols, and essential oils. These compounds are kno

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Pham, Thuy Anh Vu. "Comparison of Antimicrobial Activity against Porphyromonas gingivalis between Advanced Platelet-Rich Fibrin and Injectable Platelet-Rich Fibrin." International Journal of Biomaterials 2023 (March 27, 2023): 1–7. http://dx.doi.org/10.1155/2023/9194868.

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Platelet-rich fibrin (PRF) obtained via low-speed centrifugation has antimicrobial properties. This study was conducted to evaluate the effectiveness of advanced platelet-rich fibrin plus (A-PRF+) and injectable platelet-rich fibrin (I-PRF), obtained from patients with different periodontal states, against Porphyromonas gingivalis. A-PRF+ and I-PRF samples were obtained from venous blood of 60 subjects divided equally into three groups: periodontitis, gingivitis, and healthy gingiva groups. The antibacterial experiments evaluated biofilm inhibition, mature biofilm impact, and time-kill kinetic

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Sebe, Mayu, Satoka Senoura, Kiyoshi Miura, et al. "Antibacterial Activity of Banglene Extracted from Indonesian Ginger “Bangle” Against Porphyromonas gingivalis." International Journal of Molecular Sciences 26, no. 5 (2025): 1787. https://doi.org/10.3390/ijms26051787.

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Periodontitis is one of the most common diseases associated with the lifestyle habits of adults and is caused by the formation of biofilms, called dental plaques, in periodontal pockets by oral bacteria, such as Porphyromonas gingivalis. Bangle, Zingiber purpureum Rosc. (Indonesian ginger), a native Indonesian plant, has been traditionally consumed as food and medicine across Southeast Asia. The cis- and trans-banglenes, components of the rhizomes of Z. purpureum, have been reported to possess neurotrophic activity. Hexane extract of bangle exhibited antibacterial activity against P. gingivali

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Noori Mahal, Shaimaa, Ahmed Mohammed Turki, and Elham Hazeim Abdulkareem. "Effects of silver nanoparticles on multiple drug-resistant strains of Staphylococcus aureus from periodontal infection: An alternative approach for antimicrobial therapy." Biomedicine 43, no. 3 (2023): 908–14. http://dx.doi.org/10.51248/.v43i3.2822.

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Introduction and Aim: Most cases of periodontitis are associated with microorganisms. The Gram positive bacteria Staphylococcus aureus is considered as one of the important organisms associated with periodontal infections. This study investigated the effect of silver nanoparticles as well as the antiseptic agent chlorhexidine on multi-drug resistant S. aureus isolated from periodontal infections. Materials and Methods: In this study, with help from dentists, 266 clinical samples were collected from dental patients who had periodontal infection. S. aureus isolated from samples was tested for th

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