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1

Gopal, Shalini, Rashmi Naik, Ahmed Mujib B.R, and Arun Kumar N. "GENDER DETERMINATION USING PERIPHERAL BLOOD SMEAR." International Journal of Anatomy and Research 6, no. 2.1 (April 5, 2018): 5079–82. http://dx.doi.org/10.16965/ijar.2018.115.

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2

Lawrence, Christine, Sheldon T. Brown, and Lawrence F. Freundlich. "Peripheral blood smear bacillemia." American Journal of Medicine 85, no. 1 (July 1988): 111–13. http://dx.doi.org/10.1016/0002-9343(88)90514-1.

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3

Kapil, Menka, Rateesh Sareen, and GN Gupta. "Peripheral blood smear pathologist tool." Hematology & Transfusion International Journal 8, no. 1 (February 24, 2020): 10–11. http://dx.doi.org/10.15406/htij.2020.08.00214.

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Microscopic evaluation of a peripheral blood smear is one of the most valuable test for the diagnosis and differential diagnosis of disease inclusive of clinical history and physical examination. Despite advances in haematology automation and application of molecular techniquesits diagnostic relevance is enormous.
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4

Essgir, Prem Kumar, and Hemalatha Anantharamaiah. "A Study of Rapid Leishman Stain on Peripheral Blood Smear." Annals of Pathology and Laboratory Medicine 6, no. 4 (April 29, 2019): A201–204. http://dx.doi.org/10.21276/apalm.2323.

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5

Avci, E., B. Unver Koluman, R. Nar, H. Aybek, and S. Demİr. "Comparison of automatic peripheral blood smear to manual blood smear technique." Clinica Chimica Acta 493 (June 2019): S388—S389. http://dx.doi.org/10.1016/j.cca.2019.03.829.

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6

Tefferi, Ayalew, and Michelle A. Elliott. "Schistocytes on the Peripheral Blood Smear." Mayo Clinic Proceedings 79, no. 6 (June 2004): 809. http://dx.doi.org/10.4065/79.6.809.

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7

Edelman, M., and J. Mckitrick. "Histoplasma capsulatumin a Peripheral-Blood Smear." New England Journal of Medicine 342, no. 1 (January 6, 2000): 28. http://dx.doi.org/10.1056/nejm200001063420105.

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8

Beaudoin, Sandra, Anne Lanevschi, Marilyn Dunn, and Michel Desnoyers. "Peripheral Blood Smear from a Dog." Veterinary Clinical Pathology 31, no. 1 (March 2002): 33–35. http://dx.doi.org/10.1111/j.1939-165x.2002.tb00275.x.

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Mundi, Irneet, Ritu Pankaj, Rajeev Bedi, Anita Sharma, and Meenakshi Malhotra. "Peripheral blood smear: beyond routine morphology." Tropical Doctor 47, no. 4 (April 18, 2017): 382–84. http://dx.doi.org/10.1177/0049475517701877.

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10

Tefferi, Ayalew, and Michelle A. Elliott. "Schistocytes on the Peripheral Blood Smear." Mayo Clinic Proceedings 79, no. 6 (June 2004): 809. http://dx.doi.org/10.1016/s0025-6196(11)62635-9.

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11

Young, Edward J. "Meningococcemia Diagnosed by Peripheral Blood Smear." JAMA: The Journal of the American Medical Association 260, no. 7 (August 19, 1988): 992. http://dx.doi.org/10.1001/jama.1988.03410070120051.

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12

Young, E. J. "Meningococcemia diagnosed by peripheral blood smear." JAMA: The Journal of the American Medical Association 260, no. 7 (August 19, 1988): 992. http://dx.doi.org/10.1001/jama.260.7.992.

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13

Park, Haeseong, and Danielle Shafer. "Disseminated histoplasmosis in peripheral blood smear." Blood 123, no. 10 (March 6, 2014): 1445. http://dx.doi.org/10.1182/blood-2013-11-540120.

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14

Nadir, Erez, and Miriam Kaufshtein. "Candida albicansin a Peripheral-Blood Smear." New England Journal of Medicine 353, no. 10 (September 8, 2005): e9. http://dx.doi.org/10.1056/nejmicm041054.

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15

Grech, Mark, and David James Camilleri. "Erythrophagocytosis on the peripheral blood smear." Blood 133, no. 3 (January 17, 2019): 285. http://dx.doi.org/10.1182/blood-2018-10-879197.

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16

Singh, N. K., and S. Nagendra. "Histoplasma capsulatum in peripheral blood smear." Case Reports 2009, sep27 1 (September 28, 2009): bcr0520091877. http://dx.doi.org/10.1136/bcr.05.2009.1877.

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17

Hinge, Chhaya S., Aarti G. Ambekar, and Samidha S. Kulkarni. "Classification of RBC And WBC in Peripheral Blood Smear Using KNN." Paripex - Indian Journal Of Research 2, no. 1 (January 15, 2012): 56–58. http://dx.doi.org/10.15373/22501991/jan2013/21.

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18

Branda, John A., Mary Jane Ferraro, and Alexander Kratz. "Sensitivity of Peripheral Blood Smear Review for the Diagnosis of Candida Fungemia." Archives of Pathology & Laboratory Medicine 131, no. 1 (January 1, 2007): 97–101. http://dx.doi.org/10.5858/2007-131-97-sopbsr.

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Abstract Context.—Case reports have described detection of candidemia by examination of peripheral blood smears. It is unclear whether this method has wider applicability for early detection of fungemia. Objective.—To determine the sensitivity of smear review for detecting candidemia. Design.—Normal and cytopenic blood was spiked with increasing concentrations of yeast. Smears were prepared and reviewed by a pathologist and by technical staff. Staff members blinded to the purpose of the study first performed a routine slide review and then a targeted review for yeast. Results.—The pathologist detected isolated yeast forms at a concentration of 1 to 5 × 105 colony-forming units (CFU)/mL. When blinded to the purpose of the study, technical staff could detect Candida in most samples when the yeast concentration was 1 to 5 × 107 CFU/mL, but found it in only a small fraction of samples with lower concentrations. When asked to examine the smears specifically for yeast, they could detect it in most samples containing 1 to 5 × 106 CFU/mL. Conclusions.—Detection of candidemia by peripheral blood smear examination requires a yeast concentration of 1 to 5 × 105 CFU/mL or greater. This degree of fungemia is unusual; therefore, detection of candidemia by blood smear review will not be possible in most cases. Sensitivity of smear review for yeast detection is greatly increased if the microscopist is specifically directed to look for the presence of yeast.
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19

Pandey, Soumya, and Neslihan Cetin. "Peripheral smear clues for Bordetella pertussis." Blood 122, no. 25 (December 12, 2013): 4012. http://dx.doi.org/10.1182/blood-2013-05-502724.

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20

McPhedran, Peter, and Robert B. Hall. "Usefulness of Peripheral Blood Smears in Identifying the Causes of Anemia in Adults." Blood 106, no. 11 (November 16, 2005): 5565. http://dx.doi.org/10.1182/blood.v106.11.5565.5565.

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Abstract Anemia is common in hospital patients, being found in about half of the automated complete blood counts (CBCs) done on adults aged 20+ at our hospital. Often the reason for the anemia is immediately apparent (post-operative state, end stage renal disease without erythropoietin treatment), but often it is not. Many tests are available for the differential diagnosis of the causes of the anemia. Morphologic evaluation of a Wright-stained blood smear by a skilled observer is labor intensive, but sometimes useful in the differential diagnosis of anemia. When unexplained anemia is identified in a patient on the Medical Service at our teaching hospital, the ward team may also send an intern or a medical student to check out the smear. The potential diagnostic yield of any of these evaluations (the skilled observer, the intern, the student) is unknown. We did a prospective evaluation of 202 consecutive adults with initially unexplained anemia (Hb <12 in men, <11 in women). Using accepted, pre-established criteria for etiologic diagnosis of the causes of anemia, and available data (plus additional smear evaluations by ourselves, ferritins, free erythrocyte protoporphryns, and a few other tests) we felt we were able to establish the causes of anemia in 86% of the patients. We also referred to standard morphologic criteria for diagnosing specific blood disorders in order to see how much could be learned from the blood smears of these patients, alone. Of 147 patients whose blood smears were of acceptable quality, 30 (21%) of the blood smears were diagnostic (or close to diagnostic), and an additional 46% were supportive of the correct diagnosis. For example, iron deficiency anemia was considered the morphologic diagnosis if the blood smear showed severe hypochromia, “pencil-form” elliptocytes, and thrombocytosis. Hypochromia alone would be considered supportive of the diagnosis of iron deficiency, but require more consideration of alternatives (thalassemia trait, chronic disease, etc). Thus, in evaluating anemia in adults, a good peripheral blood smear, carefully evaluated by a trained observer, is likely to be diagnostic, or very helpful, in 20% or more of the patients.
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21

Ahnach, Maryame, Fadwa Ousti, Sara Nejjari, Mohammed Sqalli Houssaini, and Nouzha Dini. "Peripheral Blood Smear Findings in COVID-19." Turkish Journal of Hematology 37, no. 4 (November 19, 2020): 301–2. http://dx.doi.org/10.4274/tjh.galenos.2020.2020.0262.

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22

Nayal, Bhavna, S. Niveditha, Veena, and M. Chethan. "Detection of cryptococcosis in peripheral blood smear:." International Journal of Applied and Basic Medical Research 1, no. 2 (2011): 116. http://dx.doi.org/10.4103/2229-516x.91158.

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23

Kitamura, Tatsuyoshi. "Clostridium Perfringens Detected by Peripheral Blood Smear." Internal Medicine 51, no. 4 (2012): 447. http://dx.doi.org/10.2169/internalmedicine.51.6759.

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24

Demircioğlu, F., H. Ören, Ş. Yılmaz, N. Arslan, Ö. Gürcü, and G. İrken. "Abetalipoproteinemia: Importance of the peripheral blood smear." Pediatric Blood & Cancer 45, no. 2 (2005): 237. http://dx.doi.org/10.1002/pbc.20360.

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25

Lesesve, Jean François, Loïc Garçon, and Thomas Lecompte. "Finding knizocytes in a peripheral blood smear." American Journal of Hematology 87, no. 1 (April 20, 2011): 105–6. http://dx.doi.org/10.1002/ajh.22007.

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26

Buchman, Alan L. "Candida Fungemia Diagnosed From Peripheral Blood Smear." JAMA: The Journal of the American Medical Association 260, no. 19 (November 18, 1988): 2926. http://dx.doi.org/10.1001/jama.1988.03410190174045.

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27

Hörber, Sebastian, Ingo Rettig, and Andreas Peter. "Mitotic figure in the peripheral blood smear." American Journal of Hematology 93, no. 1 (June 9, 2017): 154. http://dx.doi.org/10.1002/ajh.24761.

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28

Buchman, A. L. "Candida fungemia diagnosed from peripheral blood smear." JAMA: The Journal of the American Medical Association 260, no. 19 (November 18, 1988): 2926. http://dx.doi.org/10.1001/jama.260.19.2926.

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29

Aiempanakit, Kumpol, and Benjawan Apinantriyo. "Peripheral Blood Smear of Bart’s Hydrops Fetalis." Indian Journal of Hematology and Blood Transfusion 34, no. 3 (December 8, 2017): 560–61. http://dx.doi.org/10.1007/s12288-017-0908-7.

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30

Nakai, Tokiko, and Yasuyuki Okamoto. "A megakaryocyte in a peripheral blood smear." International Journal of Hematology 110, no. 6 (October 5, 2019): 647. http://dx.doi.org/10.1007/s12185-019-02752-5.

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31

Charwudzi, Alice, Edeghonghon E. Olayemi, Ivy Ekem, Olufunmilayo Olopade, Mariann Coyle, Amma Anima Benneh, and Emmanuel Alote Allotey. "A Preliminary Study of the Suitability of Archival Bone Marrow and Peripheral Blood Smears for Diagnosis of CML Using FISH." Advances in Hematology 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/604165.

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Background.FISH is a molecular cytogenetic technique enabling rapid detection of genetic abnormalities. Facilities that can run fresh/wet samples for molecular diagnosis and monitoring of neoplastic disorders are not readily available in Ghana and other neighbouring countries. This study aims to demonstrate that interphase FISH can successfully be applied to archival methanol-fixed bone marrow and peripheral blood smear slides transported to a more equipped facility for molecular diagnosis of CML.Methods.Interphase FISH was performed on 22 archival methanol-fixed marrow (BM) and 3 peripheral blood (PB) smear slides obtained at diagnosis. The BM smears included 20 CML and 2 CMML cases diagnosed by morphology; the 3 PB smears were from 3 of the CML patients at the time of diagnosis. Six cases had knownBCR-ABLfusion results at diagnosis by RQ-PCR. Full blood count reports at diagnosis were also retrieved.Result.19 (95%) of the CML marrow smears demonstrated theBCR-ABLtranslocation. There was a significant correlation between theBCR-ABLtranscript detected at diagnosis by RQ-PCR and that retrospectively detected by FISH from the aged BM smears at diagnosis (r=0.870;P=0.035).Conclusion.Archival methanol-fixed marrow and peripheral blood smears can be used to detect theBCR-ABLtranscript for CML diagnosis.
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32

Mallappa, Sumanashree, Sachin Kolte, Nimisha Sharma, and Indrani Dhawan. "Assessment Of Peripheral Blood Smear Preparation Technique In Laboratories With High Sample Load." Annals of Applied Bio-Sciences 4, no. 4 (October 14, 2017): A150—A156. http://dx.doi.org/10.21276/aabs.1655.

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33

Potkonjak, Aleksandar, Branislav Lako, Branislava Belic, Nikolina Milosevic, Ognjen Stevancevic, Marko Cincovic, and Bjanka Lako. "Investigations of significance of blood smear results in diagnostics of infectious and parasitic diseases in dogs." Veterinarski glasnik 64, no. 5-6 (2010): 375–84. http://dx.doi.org/10.2298/vetgl1006375p.

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The microscopic examination of stained smears of peripheral blood is of vital significance in the speedy diagnostics of infectious and parasitic diseases, in particular during the stage of infection when the cause is present in the blood, or blood cells. It is sometimes possible to make a definitive diagnosis of an infectious or parasitic disease following an examination of a stained smear of the peripheral blood. Since microscopic examinations of a peripheral blood smear are applied increasingly rarely in clinical practice, due to the development of other methods for the diagnostics of infectious and parasitic diseases in dogs, as well as the lack of knowledge of the morphology of the numerous causes that can be present in the blood, we carried out an investigation into the presence and spread of infections whose causes can be present in dog blood. The investigations covered 100 dogs from which peripheral blood smears were taken and then stained with a Giemsa solution according to the standard protocol and examined under a microscope with an immersion lens. The examination of peripheral blood smears stained according to Giemsa resulted in the identification of the presence of an Ehrlichia spp. morula in a neutrophil granulocyte in one dog. The presence of hemotropic mycoplasmas was established in erythrocytes of eleven dogs, while the presence of the protozoa Babesia canis in erythrocytes was identified in five dogs included in the investigations. A microscopic examination of dog peripheral blood smears stained according to Giemsa was shown as a speedy, practical, simple, and inexpensive method for making a definitive etiological diagnosis of these infections, and it should be included regularly in standard protocols for the diagnostics of infectious and parasitic diseases.
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34

Sakaguchi, Shota, Atsushi Kisanuki, Seiichiro Hara, and Akihiko Okayama. "Streptococcus pneumoniae Detected on a Peripheral Blood Smear." Internal Medicine 53, no. 4 (2014): 347. http://dx.doi.org/10.2169/internalmedicine.53.1618.

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35

Maltos, André Luiz, Evaldo Maia, and Cristina da Cunha Hueb Barata de Oliveira. "Disseminated histoplasmosis diagnosed in a peripheral blood smear." Revista da Sociedade Brasileira de Medicina Tropical 50, no. 1 (February 2017): 148. http://dx.doi.org/10.1590/0037-8682-0189-2016.

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36

Naugler, Christopher, EmadA Mohammed, MostafaM A. Mohamed, and BehrouzH Far. "Peripheral blood smear image analysis: A comprehensive review." Journal of Pathology Informatics 5, no. 1 (2014): 9. http://dx.doi.org/10.4103/2153-3539.129442.

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37

Cha, Choong-Hwan, and Jeong Uk Kim. "Endothelial cells in peripheral blood smear: an artifact?" Korean Journal of Hematology 45, no. 3 (2010): 150. http://dx.doi.org/10.5045/kjh.2010.45.3.150.

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38

Elin, Ronald J., Janine Whitis, and James Snyder. "Infectious Disease Diagnosis From a Peripheral Blood Smear." Laboratory Medicine 31, no. 6 (June 2000): 324–28. http://dx.doi.org/10.1309/alpg-6uud-14b7-k6xp.

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39

Lee, AC. "Haematologist-reviewed peripheral blood smear in paediatric practice." Singapore Medical Journal 59, no. 2 (February 2018): 64–68. http://dx.doi.org/10.11622/smedj.2018013.

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40

Wagner, Kenneth F. "Antibiotic Therapy Based on Stained Peripheral Blood Smear." Archives of Internal Medicine 145, no. 2 (February 1, 1985): 369. http://dx.doi.org/10.1001/archinte.1985.00360020213045.

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41

Johnson, D. A. "Antibiotic therapy based on stained peripheral blood smear." Archives of Internal Medicine 145, no. 2 (February 1, 1985): 369b—369. http://dx.doi.org/10.1001/archinte.145.2.369b.

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42

Arneth, Borros, Christian Keller, and Sylvia Schaefer. "Malaria exflagellation in a human peripheral blood smear." IDCases 10 (2017): 51–52. http://dx.doi.org/10.1016/j.idcr.2017.08.010.

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43

Alwar, Vanamala, Reeti Kavdia, Nandini Singh, and Karuna Rameshkumar. "Hunt for the Hidden Trait." Journal of Laboratory Physicians 1, no. 01 (January 2009): 015–18. http://dx.doi.org/10.4103/0974-2727.54802.

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ABSTRACT Objective: To assess the efficacy of a peripheral smear examination as a screening tool for β-thalassemia trait. Materials and Methods: 17 623 Leishman-stained peripheral smears were evaluated during the period from July 2006 to September 2007. The following parameters were studied: hemoglobin, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and red cell distribution width. All the cases that showed microcytosis, hypochromia, erythrocytosis and absence of anisopoikilocytosis were suspected of having the thalassemia trait (TT), and all these cases were further evaluated with Alkaline Hemoglobin Electrophoresis for confirmation. Results: Of the 17 623 smears examined, 60 cases were considered suspicious of having TT. Alkaline hemoglobin electrophoresis carried out on all these cases revealed an elevated HbA 2 (Mean = 7.5%). Five cases evaluated were found to have other hemoglobinopathies (1 Sickle cell trait, 3 Hb-E, 1 thalassemia intermedia). Conclusion: Careful screening of peripheral smear is an invaluable screening tool for thalassemia trait (PPV - 95%). There must be awareness among the peripheral centers about the importance of peripheral smear screening and the affected persons should be counseled.
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44

Berber, Ilhami, Ozlem Cagasar, Ahmet Sarıcı, Nurcan Kirici Berber, Ismet Aydogdu, Asli Yildirim, Harika Gozde Gocukara Bag, Leman Acun Delen, and Ozkan Ulutas. "SIMPLE PERIPHERAL BLOOD SMEAR FINDINGS OF COVID-19 PATIENTS PROVIDE INFORMATION ABOUT THE SEVERITY OF THE DISEASE AND THE DURATION OF HOSPITAL STAY." Mediterranean Journal of Hematology and Infectious Diseases 13, no. 1 (December 31, 2020): e2021009. http://dx.doi.org/10.4084/mjhid.2021.009.

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Backround Data about the morphological changes of Covid-19 infection in peripheral blood smear are limited and association with clinical severity of the disease are not known yet. We aimed to examine the characteristics of the cells detected in the pathological rate and / or appearance and whether these findings are related to the clinical course by evaluating the peripheral blood smear at the time of diagnosis in Covid-19 patients. Methods Clinical features, laboratory data, peripheral blood smear of fifty patients diagnosed with Covid-19 by PCR was evaluated at diagnosis. Peripheral smear samples of the patients were compared with the age and sex matched 30 healthy controls. Pictures were taken from the paitients’peripheral blood smear. Patients were divided into two groups. Early and advanced stage patient groups were compared in terms of laboratory data and peripheral smear findings. The relationship between the laboratory values of all patients and the duration of hospitalization was analyzed. Results Pseudo pelger-huet, atypical lymphocytes, vacuole monocytes and pycnotic neutrophils rates were high in the patient group. Increased pseudo pelger-huet anomaly, psodo-pelger huet/mature lymphocyte ratio, decreased number of mature lymphocytes, and eosinophils in peripheral blood smear were observed in the advanced stage patients (p <0.05). A negative correlation was observed between the duration of hospitalization and mature lymphocyte, and monocytes with vacuoles rates (p <0.05). Conclusion Peripheral smear is a cheap, easily performed, and rapid test. Increased pseudo-pelger huet anomaly/mature lymphocytes rate is suggesting advanced stage disease, while high initial monocytes with vacuoles and mature lymphocyte rates at the time of diagnosis may be an indicator of shortened duration of hospitalization.
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45

Leke, Rose F. G., Rosine R. Djokam, Robinson Mbu, Robert J. Leke, Josephine Fogako, Rosette Megnekou, Simon Metenou, et al. "Detection of the Plasmodium falciparumAntigen Histidine-Rich Protein 2 in Blood of Pregnant Women: Implications for Diagnosing Placental Malaria." Journal of Clinical Microbiology 37, no. 9 (1999): 2992–96. http://dx.doi.org/10.1128/jcm.37.9.2992-2996.1999.

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Pregnant women have an increased susceptibility to infection byPlasmodium falciparum. Parasites may be present in the placenta yet not detectable in peripheral blood smears by routine light microscopy. In order to determine how frequently misdiagnosis occurs, peripheral blood and placental samples were collected from 1,077 Cameroonian women at the time of giving birth and examined for the presence of malarial parasites by using light microscopy. Results showed that 20.1% of the women who had placental malaria were peripheral blood smear negative. Thus, malarial infection was not detected by microscopic examination of peripheral blood smears from approximately one out of five malaria-infected women. Since P. falciparum parasites secrete histidine-rich protein 2 (HRP-2), we sought to determine if detecting HRP-2 in either peripheral plasma or whole blood might be used to diagnose the presence of parasites “hidden” in the placenta. Samples of peripheral plasma from 127 women with different levels of placental malarial infection were assayed by HRP-2-specific enzyme-linked immunosorbent assay. HRP-2 was detected in 88% of the women with placental malaria who tested negative by blood smear. Additionally, whole blood was obtained from 181 women and tested for HRP-2 with a rapid, chromatographic strip test (ICT). The ICT test accurately detected malarial infection in 89.1% ofP. falciparum-infected women. Furthermore, 94% of women with malaria were accurately diagnosed by using a combination of microscopy and the ICT test. Thus, detection of HRP-2 in conjunction with microscopy should improve diagnosis of malaria in pregnant women.
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46

Lopez, Carolina, Yurley Alvarez, Eliana Arango, Jaime Carmona-Fonseca, and Amanda Maestre. "Microscopic detection of hemozoin in peripheral leukocytes fails to indicate plasmodial placental infection in pregnant women." Journal of Infection in Developing Countries 11, no. 06 (June 29, 2017): 487–92. http://dx.doi.org/10.3855/jidc.9182.

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Introduction: Malaria in pregnancy very often includes gestational (parasites in maternal peripheral blood) and placental (parasites in placental blood) infection, but the later condition can only be detected after delivery. High frequency of placental plasmodial infection has been confirmed in many countries and is associated with negative birth outcomes. With the hypothesis that placental infection is accompanied by hemozoin circulation in maternal peripheral blood, an exploratory study was conducted to evaluate the association between peripheral leukocytes with hemozoin and placental infection by Plasmodium vivax or Plasmodium falciparum in parturient women. Methodology: A descriptive, transversal and exploratory (pilot type) study was carried out with women from two malaria-endemic localities of northwest Colombia. A total of 25 parturient women with confirmed placental infection and 25 without placental infection were included. Two independent readers measured the number of leukocytes with hemozoin in thick smears of maternal peripheral blood. Plasmodial infection in maternal peripheral blood and placental blood was detected by thick smear and quantitative polymerase chain reaction (qPCR). Results: Four parturient women had leukocytes with hemozoin in peripheral blood; three of them had placental plasmodial infection and one was negative for placental infection. No statistically significant association between leukocytes with hemozoin in peripheral blood and placental infection was observed. Conclusions: With this limited sample size, detection of leukocytes with hemozoin by thick smear of maternal peripheral blood did not indicate presence of placental infection.
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47

Chandrashekar, Vani, and Mamta Soni. "Florid Erythrophagocytosis on the Peripheral Smear." Journal of Laboratory Physicians 4, no. 01 (January 2012): 059–61. http://dx.doi.org/10.4103/0974-2727.98679.

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ABSTRACTanemias and sporadically in few other conditions. Here, we report a case of florid erythrophagocytosis with severe anemia following a viral infection in an 18-year-old girl. Her complete blood count (CBC) revealed hemoglobin of 3.6 gm/dl and a hematocrit of 10%. The peripheral smear showed erythrophagocytosis by neutrophils and rosetting of erythrocytes around neutrophils. The direct Coombs test and direct Donath- Landsteiner tests were positive.
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48

Lehmann, Lisa Soleymani, and Jerry L. Spivak. "Rapid and Definitive Diagnosis of Infectious Diseases Using Peripheral Blood Smears." Journal of Intensive Care Medicine 7, no. 1 (January 1992): 36–47. http://dx.doi.org/10.1177/088506669200700105.

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A timely diagnosis is essential in the management of septicemia and septic shock. Three patients are described, all of whom presented with fever and one of whom was hypotensive at the time of admission. In each patient, rapid diagnosis of the cause of fever was possible because microorganisms were identified on a peripheral blood smear obtained at the time of admission. This identification permitted prompt initiation of appropriate antimicrobial therapy. In addition, a literature review of use of peripheral blood smears in the diagnosis of bacterial, fungal, and parasitic infections is provided.
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49

Muraleedharan, Arya Puthukkat, and Prabhalakshmy Kuzhikkattil Krishnankutty. "Bone Marrow and Peripheral Blood Evaluation in Non-Hodgkin Lymphoma – A Cross Sectional Study of 78 Cases in a Tertiary Care Centre in Kerala." Journal of Evidence Based Medicine and Healthcare 8, no. 32 (August 9, 2021): 2943–49. http://dx.doi.org/10.18410/jebmh/2021/538.

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Abstract:
BACKGROUND In the evaluation of patients with non-Hodgkin lymphoma (NHL), determination of bone marrow involvement is an integral part of staging work up. Peripheral blood counts and examination of blood smears are also done in patients with lymphoma as part of pre-treatment investigations. METHODS A cross sectional study of 78 patients with a prior histopathological diagnosis of NHL was conducted. Peripheral blood counts were performed on an automated haematology analyser to look for various cytopenias. Peripheral blood smears and bone marrow aspirate (BMA) / imprint smears were examined in detail for atypical lymphoid cells. Bone marrow trephine biopsies of these patients were studied to assess the NHL involvement and the various patterns of involvement. Adjuvant immunohistochemistry (IHC) was performed in bone marrow biopsies with scant cellularity or crush artefact to discern the marrow involvement. RESULTS Bone marrow trephine biopsy showed involvement by lymphoma in 65.4 % cases. The incidence of involvement was higher in B-cell lymphomas, especially in low grade types. The predominant pattern of involvement was interstitial pattern (41.2 %). Discordant histology between bone marrow and the primary anatomic site was found in 7.8 % of the cases, which was seen more in diffuse large B-cell lymphomas. Majority of the patients with bone marrow infiltration by NHL had anaemia (84.3 %). Bicytopenia and pancytopenia were also observed. On peripheral blood smear examination atypical lymphoid cells were present in 23 % cases. CONCLUSIONS Bone marrow examination is an important aspect in the diagnosis of NHL, because of its both prognostic and therapeutic implications. Hence, the presence of atypical lymphoid cells and other changes in the peripheral blood should be detected in these patients. KEYWORDS Non-Hodgkin Lymphoma, Bone Marrow Biopsy, Bone Marrow Aspirate / Imprint, Peripheral Blood Smear, Atypical Lymphoid Cells
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50

Westblade, Lars F., and Carey-Ann D. Burnham. "Yeast-like intraleukocytic inclusions in a peripheral smear." Blood 119, no. 5 (February 2, 2012): 1105. http://dx.doi.org/10.1182/blood-2011-03-343616.

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