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Journal articles on the topic 'Peripheral pulse'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

Mikaelian, H. H. "Psychology of Computer Use: IV. Effects of Video Display Units on Fundamental Visual Processes: Temporal Resolution." Perceptual and Motor Skills 66, no. 3 (June 1988): 951–62. http://dx.doi.org/10.2466/pms.1988.66.3.951.

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Measures of two-pulse resolution (2PR) using foveally and peripherally viewed targets were obtained before and after reading videotext and print. Three pulse durations (25, 250, and 300 msec) were used. The results showed that (a) 2PR on the fovea is about a fourth of that on the periphery, (b) peripheral 2PR increases following reading videotext, and (c) no appreciable effects occur following reading print.

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2

Li, Ye, Antoine Guilcher, Samuel Vennin, Jordi Alastruey-arimon, and Phil Chowienczyk. "P1 DETERMINANTS OF PERIPHERAL PULSE PRESSURE AND PULSE PRESSURE AMPLIFICATION." Artery Research 24, no. C (2018): 80. http://dx.doi.org/10.1016/j.artres.2018.10.054.

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3

Kuvin, J. T., M. Sidhu, A. R. Patel, K. A. Sliney, N. G. Pandian, and R. H. Karas. "Pulse pressure and peripheral arterial vasoreactivity." Journal of Human Hypertension 19, no. 6 (February 24, 2005): 501–2. http://dx.doi.org/10.1038/sj.jhh.1001844.

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4

Vasan, Ramachandran S. "Pathogenesis of Elevated Peripheral Pulse Pressure." Hypertension 51, no. 1 (January 2008): 33–36. http://dx.doi.org/10.1161/hypertensionaha.107.101196.

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5

Murray, Willie Bosseau, and Patrick Anthony Foster. "The peripheral pulse wave: Information overlooked." Journal of Clinical Monitoring 12, no. 5 (September 1996): 365–77. http://dx.doi.org/10.1007/bf02077634.

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6

Fushimi, Yasutaka, Tomohisa Okada, Akira Yamamoto, Mitsunori Kanagaki, Koji Fujimoto, and Kaori Togashi. "Timing dependence of peripheral pulse-wave-triggered pulsed arterial spin labeling." NMR in Biomedicine 26, no. 11 (June 20, 2013): 1527–33. http://dx.doi.org/10.1002/nbm.2986.

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7

Gottlieb, Michael D., and Mitchell L. Kietzman. "Two-Pulse Temporal Integration Functions in the Fovea and Peripheral Retina." Perceptual and Motor Skills 64, no. 2 (April 1987): 343–54. http://dx.doi.org/10.2466/pms.1987.64.2.343.

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The temporal integration of luminous energy was compared in the fovea and at 7° eccentricity using two-pulse stimuli and two methodologies The two-pulse stimuli consisted of two 1-msec. light pulses separated by intervals of darkness ranging from 1 to 400 msec; they were provided by a glow modulator tube transilluminating a 21.8' opal glass target. In Exp. 1 (equal-performance design), integration functions were generated using a forced-choice staircase procedure to estimate threshold luminance. The data for two Os showed that the critical duration (CD), and thus the period of complete integra

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8

Johnson, Kelly C., Zilong Xie, Maureen J. Shader, Paul G. Mayo, and Matthew J. Goupell. "Effect of Chronological Age on Pulse Rate Discrimination in Adult Cochlear-Implant Users." Trends in Hearing 25 (January 2021): 233121652110073. http://dx.doi.org/10.1177/23312165211007367.

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Cochlear-implant (CI) users rely heavily on temporal envelope cues to understand speech. Temporal processing abilities may decline with advancing age in adult CI users. This study investigated the effect of age on the ability to discriminate changes in pulse rate. Twenty CI users aged 23 to 80 years participated in a rate discrimination task. They attempted to discriminate a 35% rate increase from baseline rates of 100, 200, 300, 400, or 500 pulses per second. The stimuli were electrical pulse trains delivered to a single electrode via direct stimulation to an apical (Electrode 20), a middle (

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9

Korhonen, P., H. Kautiainen, and P. Aarnio. "Pulse pressure and subclinical peripheral artery disease." Journal of Human Hypertension 28, no. 4 (October 17, 2013): 242–45. http://dx.doi.org/10.1038/jhh.2013.99.

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10

Safar, Michel E. "Peripheral Pulse Pressure, Large Arteries, and Microvessels." Hypertension 44, no. 2 (August 2004): 121–22. http://dx.doi.org/10.1161/01.hyp.0000135448.73199.75.

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11

Takazawa, K., and C. Ibukiyama. "Relationship between central and peripheral pulse waveforms." Pathophysiology 1 (November 1994): 322. http://dx.doi.org/10.1016/0928-4680(94)90661-0.

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12

Talke, Pekka, and Claudia Stapelfeldt. "Effect of Peripheral Vasoconstriction on Pulse Oximetry." Journal of Clinical Monitoring and Computing 20, no. 5 (July 14, 2006): 305–9. http://dx.doi.org/10.1007/s10877-006-9022-3.

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13

Mueller, Niklas, Joachim Streis, Sandra Müller, Hermann Pavenstädt, Thomas Felderhoff, Stefan Reuter, and Veit Busch. "Pulse Wave Analysis and Pulse Wave Velocity for Fistula Assessment." Kidney and Blood Pressure Research 45, no. 4 (2020): 576–88. http://dx.doi.org/10.1159/000506741.

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Background/Aims: Pulse wave analysis (PWA) and pulse wave velocity (PWV) provide information about arterial stiffness and elasticity, which is mainly used for cardiovascular risk stratification. In the presented prospective observational pilot study, we examined the hypothesis that radiocephalic fistula (RCF)-related changes of haemodynamics and blood vessel morphology including high as well as low flow can be seen in specific changes of pulse wave (PW) morphology. Methods: Fifty-six patients with RCF underwent local ambilateral peripheral PWA and PWV measurement with the SphygmoCor® device. G

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14

Mullan, Brian A., Ciaran N. Ennis, Howard J. P. Fee, Ian S. Young, and David R. McCance. "Protective effects of ascorbic acid on arterial hemodynamics during acute hyperglycemia." American Journal of Physiology-Heart and Circulatory Physiology 287, no. 3 (September 2004): H1262—H1268. http://dx.doi.org/10.1152/ajpheart.00153.2003.

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Mortality increases when acute coronary syndromes are complicated by stress-induced hyperglycemia. Early pulse wave reflection can augment central aortic systolic blood pressure and increase left ventricular strain. Altered pulse wave reflection may contribute to the increase in cardiac risk during acute hyperglycemia. Chronic ascorbic acid (AA) supplementation has recently been shown to reduce pulse wave reflection in diabetes. We investigated the in vivo effects of acute hyperglycemia, with and without AA pretreatment, on pulse wave reflection and arterial hemodynamics. Healthy male voluntee

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15

Munir, Shahzad, Antoine Guilcher, Tamra Kamalesh, Brian Clapp, Simon Redwood, Michael Marber, and Philip Chowienczyk. "Peripheral Augmentation Index Defines the Relationship Between Central and Peripheral Pulse Pressure." Hypertension 51, no. 1 (January 2008): 112–18. http://dx.doi.org/10.1161/hypertensionaha.107.096016.

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16

Husmann, Marc, Vincenzo Jacomella, Christoph Thalhammer, and Beatrice R. Amann-Vesti. "Markers of arterial stiffness in peripheral arterial disease." Vasa 44, no. 5 (September 2015): 341–48. http://dx.doi.org/10.1024/0301-1526/a000452.

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Abstract. Increased arterial stiffness results from reduced elasticity of the arterial wall and is an independent predictor for cardiovascular risk. The gold standard for assessment of arterial stiffness is the carotid-femoral pulse wave velocity. Other parameters such as central aortic pulse pressure and aortic augmentation index are indirect, surrogate markers of arterial stiffness, but provide additional information on the characteristics of wave reflection. Peripheral arterial disease (PAD) is characterised by its association with systolic hypertension, increased arterial stiffness, distur

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17

Lechelt, Eugene C. "A Comparison of Local and Remote Masking on Tactile Pulse Detection Using Different Masking Patterns." Perceptual and Motor Skills 63, no. 2 (October 1986): 343–51. http://dx.doi.org/10.2466/pms.1986.63.2.343.

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Forward and backward masking functions were obtained for the detection of a 2-msec. tactile “test” pulse using two different masking patterns (5- or 10-pulse sequences) under conditions of both local and remote masking. Twelve ISIs (interval between “test” pulse and onset of the masking sequence) ranging from 10 to 76 msec. were used. A two-interval forced-choice (2-IFC) procedure was used in which observers were presented with two successive trains of tactile pulses, one having the “test” pulse at varying intervals prior (backward masking) to or after (forward masking) the masking sequence an

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18

Lee, Ki Nam, Sun Seob Choi, Yung Il Lee, Byeong Ho Park, Jae Ik Kim, Jung Mi Lee, and Kyeong Jin Nam. "Peripheral Arterial Thrombolysis by Modified Pulse-Spray Method." Journal of the Korean Radiological Society 30, no. 5 (1994): 835. http://dx.doi.org/10.3348/jkrs.1994.30.5.835.

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19

Yusuf, S. W., S. C. Whitaker, R. H. S. Gregson, P. W. Wenham, B. R. Hopkinson, and G. S. Makin. "Experience with pulse-spray technique in peripheral thrombolysis." European Journal of Vascular Surgery 8, no. 3 (May 1994): 270–75. http://dx.doi.org/10.1016/s0950-821x(05)80141-0.

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20

Millasseau, Sandrine C., Sundip J. Patel, Simon R. Redwood, James M. Ritter, and Philip J. Chowienczyk. "Pressure Wave Reflection Assessed From the Peripheral Pulse." Hypertension 41, no. 5 (May 2003): 1016–20. http://dx.doi.org/10.1161/01.hyp.0000057574.64076.a5.

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21

Sessler, Daniel I. "Pulse Oximetry May Not Reliably Assess Peripheral Perfusion." Anesthesiology 88, no. 4 (April 1, 1998): 1129. http://dx.doi.org/10.1097/00000542-199804000-00046.

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22

Thakur, Sangeeta, S. K. Mishra, and Ajay Sharma. "Use of pulse oximetry in peripheral arterial injury." Indian Journal of Thoracic and Cardiovascular Surgery 10, no. 1 (June 1994): 67–68. http://dx.doi.org/10.1007/bf02860886.

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23

Gunter, Sule, Chanel Robinson, Gavin R. Norton, Angela J. Woodiwiss, Linda Tsang, Patrick H. Dessein, and Aletta M. E. Millen. "Cardiovascular Risk Factors and Disease Characteristics Are Consistently Associated with Arterial Function in Rheumatoid Arthritis." Journal of Rheumatology 44, no. 8 (June 1, 2017): 1125–33. http://dx.doi.org/10.3899/jrheum.170029.

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Objective.Arterial properties influence cardiovascular disease (CVD) risk. We identified potential determinants of arterial function in patients with rheumatoid arthritis (RA).Methods.Relationships of traditional cardiovascular risk factors and RA characteristics with arterial stiffness (pulse wave velocity), wave reflection (augmentation index, reflected wave pressure, and reflection magnitude), and pressure pulsatility (central systolic and pulse pressure, peripheral pulse pressure, pulse pressure amplification, and forward wave pressure) were identified in multivariable backward regression

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24

Pugovkin, Andrey Petrovich, Nikolay Aleksandrovich Verlov, Sergey Borisovich Landa, and Valeriy Olegovich Yerkudov. "The systemic arterial pressure waveform management by means of the study of peripheral vessels." Pediatrician (St. Petersburg) 5, no. 1 (March 15, 2014): 76–81. http://dx.doi.org/10.17816/ped5176-81.

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The systemic arterial pressure waveform was reconstructed from peripheral pulse curve measured dy volume-clump method with sphygmoarteriorhythmograph SACR-2 by means of specially designed transfer function. The restored pulse curve was compared with that obtained from peripheral pulse curve measured with appliqué gauge and software of the Sphygmocor cardiovascular system. The comparative study revealed the identity of results obtained via both approache.

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25

Makowski, Katherine N., Michael J. Kreisman, Richard B. McCosh, Ali A. Raad та Kellie M. Breen. "Peripheral interleukin-1β inhibits arcuate kiss1 cells and LH pulses in female mice". Journal of Endocrinology 246, № 2 (серпень 2020): 149–60. http://dx.doi.org/10.1530/joe-20-0165.

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Peripheral immune/inflammatory challenges rapidly disrupt reproductive neuroendocrine function. This inhibition is considered to be centrally mediated via suppression of gonadotropin-releasing hormone secretion, yet the neural pathway(s) for this effect remains unclear. We tested the hypothesis that interleukin-1β inhibits pulsatile luteinizing hormone secretion in female mice via inhibition of arcuate kisspeptin cell activation, a population of neurons considered to be the gonadotropin-releasing hormone pulse generator. In the first experiment, we determined that the inhibitory effect of peri

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26

Iliopoulos, Fivos, Till Nierhaus, and Arno Villringer. "Electrical noise modulates perception of electrical pulses in humans: sensation enhancement via stochastic resonance." Journal of Neurophysiology 111, no. 6 (March 15, 2014): 1238–48. http://dx.doi.org/10.1152/jn.00392.2013.

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Although noise is usually considered to be harmful for signal detection and information transmission, stochastic resonance (SR) describes the counterintuitive phenomenon of noise enhancing the detection and transmission of weak input signals. In mammalian sensory systems, SR-related phenomena may arise both in the peripheral and the central nervous system. Here, we investigate behavioral SR effects of subliminal electrical noise stimulation on the perception of somatosensory stimuli in humans. We compare the likelihood to detect near-threshold pulses of different intensities applied on the lef

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27

Avolio, A. P., W. W. Nichols, and M. F. O'Rourke. "Propagation of pressure pulse in kangaroo arterial system." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 249, no. 3 (September 1, 1985): R335—R340. http://dx.doi.org/10.1152/ajpregu.1985.249.3.r335.

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The pressure pulse contour in the ascending aorta of kangaroos is markedly different from that seen in other species, but the changes undergone by the pulse propagating along the aorta are quite similar. Alteration of wave contour and progressive amplification of the pulse in the distal aorta and peripheral arteries of other mammals have been attributed to elastic nonuniformity of the aorta and to peripheral wave reflection. In kangaroos the aorta approximates a uniform tube with essentially constant viscoelastic properties, whereas wave reflection from the lower body appears to be unusually i

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28

Lewis, Jane EA, Paul Williams, and Jane H. Davies. "Non-invasive assessment of peripheral arterial disease: Automated ankle brachial index measurement and pulse volume analysis compared to duplex scan." SAGE Open Medicine 4 (January 1, 2016): 205031211665908. http://dx.doi.org/10.1177/2050312116659088.

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Objectives: This cross-sectional study aimed to individually and cumulatively compare sensitivity and specificity of the (1) ankle brachial index and (2) pulse volume waveform analysis recorded by the same automated device, with the presence or absence of peripheral arterial disease being verified by ultrasound duplex scan. Methods: Patients (n=205) referred for lower limb arterial assessment underwent ankle brachial index measurement and pulse volume waveform recording using volume plethysmography, followed by ultrasound duplex scan. The presence of peripheral arterial disease was recorded if

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29

Ogawa, Keishi, Munetaka Sugiishi, Hirofumi Anno, Kazuhiro Katada, Koujiroh Yamaguti, Takehiko Goroh, and Sigeki Saitoh. "162. Evaluation of peripheral pulse gating method on MRI." Japanese Journal of Radiological Technology 47, no. 2 (1991): 273. http://dx.doi.org/10.6009/jjrt.kj00003322948.

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30

Jindal, GD, SushmaN Bhat, ManasiS Sawant, and AlakaK Deshpande. "Role of harmonics and subharmonics in peripheral pulse analysis." MGM Journal of Medical Sciences 7, no. 3 (2020): 141. http://dx.doi.org/10.4103/mgmj.mgmj_47_20.

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31

Whitaker, S., S. Yusuf, R. Gregson, J. Astil, P. Wenham, B. Hopkinson, and G. Makin. "Accelerated peripheral arterial thrombolysis using the Pulse-Spray method." Clinical Radiology 48, no. 5 (November 1993): 343–44. http://dx.doi.org/10.1016/s0009-9260(05)81329-7.

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32

Sorelli, Michele, Antonia Perrella, and Leonardo Bocchi. "Detecting Vascular Age Using the Analysis of Peripheral Pulse." IEEE Transactions on Biomedical Engineering 65, no. 12 (December 2018): 2742–50. http://dx.doi.org/10.1109/tbme.2018.2814630.

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33

Kallmunzer, B., T. Bobinger, N. Kahl, M. Kopp, N. Kurka, M. J. Hilz, L. Marquardt, S. Schwab, and M. Kohrmann. "Peripheral pulse measurement after ischemic stroke: A feasibility study." Neurology 83, no. 7 (July 23, 2014): 598–603. http://dx.doi.org/10.1212/wnl.0000000000000690.

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34

Jawahar, David, H. R. Rachamalla, Alicja Rafalowski, R. Ilkhani, T. Bharathan, N. Anandarao, and David Jawahar. "Pulse Oximetry in the Evaluation of Peripheral Vascular Disease." Angiology 48, no. 8 (August 1997): 721–24. http://dx.doi.org/10.1177/000331979704800808.

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35

Johnson, Nicholas, ValerieA Johnson, Jeffrey Bannister, and RichardJ Lilford. "MEASUREMENT OF FETAL PERIPHERAL PERFUSION WITH A PULSE OXIMETER." Lancet 333, no. 8643 (April 1989): 898. http://dx.doi.org/10.1016/s0140-6736(89)92887-0.

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36

Cavaye, Douglas M., Marwan R. Tabbara, George E. Kopchok, and Rodney A. White. "Continuous Piezoelectric Pulse-Sensor Monitoring of Peripheral Vascular Reconstructions." Vascular Surgery 26, no. 9 (November 1992): 718–22. http://dx.doi.org/10.1177/153857449202600905.

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37

Totah, A., B. Kallmunzer, and M. Kohrmann. "Peripheral pulse measurement after ischemic stroke: A feasibility study." Neurology 84, no. 9 (March 2, 2015): 962–63. http://dx.doi.org/10.1212/01.wnl.0000462308.68863.ff.

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38

Kuznetsova, Tatiana, Gregory Szczesny, Lutgarde Thijs, Dominique Jozeau, Jan D’hooge, and Jan A. Staessen. "Assessment of peripheral vascular function with photoplethysmographic pulse amplitude." Artery Research 5, no. 2 (2011): 58. http://dx.doi.org/10.1016/j.artres.2011.03.001.

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39

Vegfors, Magnus, Björn Tryggvason, Folke Sjöberg, and Claes Lennmarken. "Assessment of peripheral blood flow using a pulse oximeter." Journal of Clinical Monitoring 6, no. 1 (January 1990): 1–4. http://dx.doi.org/10.1007/bf02832175.

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40

Baertschi, Alex J., Yves Massy, and Smi Kwon. "Vasopressin responses to peripheral and central osmotic pulse stimulation." Peptides 6, no. 6 (November 1985): 1131–35. http://dx.doi.org/10.1016/0196-9781(85)90439-5.

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41

Skeen, James T., W. Walter Backus, Alec R. Hovagim, and Paul J. Poppers. "Intraoperative pulse oximetry in peripheral revascularization in an infant." Journal of Clinical Monitoring 4, no. 4 (October 1988): 272–73. http://dx.doi.org/10.1007/bf01617326.

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42

Pälve, Heikki. "Reflection and transmission pulse oximetry during compromised peripheral perfusion." Journal of Clinical Monitoring 8, no. 1 (January 1992): 12–15. http://dx.doi.org/10.1007/bf01618081.

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43

Bebout, Donald E., and Paul D. Mannheimer. "Effects of Cold-Induced Peripheral Vasoconstriction on Pulse Amplitude at Various Pulse Oximeter Sensor Sites." Anesthesiology 96, Sup 2 (September 2002): A558. http://dx.doi.org/10.1097/00000542-200209002-00558.

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44

Brand, M., A. J. Woodiwiss, F. Michel, H. L. Booysen, M. G. Veller, and G. R. Norton. "A Mismatch Between Aortic Pulse Pressure and Pulse Wave Velocity Predicts Advanced Peripheral Arterial Disease." European Journal of Vascular and Endovascular Surgery 46, no. 3 (September 2013): 338–46. http://dx.doi.org/10.1016/j.ejvs.2013.06.005.

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45

Driscoll, M. Darcy, J. Malcolm, O. Arnold, Gordon E. Marchiori, Linda A. Harker, and Marvin H. Sherebrin. "Determination of Appropriate Recording Force for Non-Invasive Measurement of Arterial Pressure Pulses." Clinical Science 92, no. 6 (June 1, 1997): 559–66. http://dx.doi.org/10.1042/cs0920559.

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1. Non-invasive recording techniques of the arterial pressure pulse will distort the arterial wall and may alter pulse wave measurements. We hypothesized that intersubject variability of these measurements would be reduced if recording forces were normalized to reflect individualized arterial occlusion forces. 2. In 10 normal male subjects (age 24 ± 1 years), brachial, radial and finger arterial pressure pulses were recorded simultaneously using volume displacement pulse transducers (Fukuda TY-303) and a finger pressure monitoring system (Finapres, Ohmeda 2300) and were made at 2, 5 and 10–100

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46

Guérit, François, Jeremy Marozeau, Bastian Epp, and Robert P. Carlyon. "Effect of the Relative Timing between Same-Polarity Pulses on Thresholds and Loudness in Cochlear Implant Users." Journal of the Association for Research in Otolaryngology 21, no. 6 (August 24, 2020): 497–510. http://dx.doi.org/10.1007/s10162-020-00767-y.

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Abstract The effect of the relative timing between pairs of same-polarity monophasic pulses has been studied extensively in single-neuron animal studies and has revealed fundamental properties of the neurons. For human cochlear implant listeners, the requirement to use charge-balanced stimulation and the typical use of symmetric, biphasic pulses limits such measures, because currents of opposite polarities interact at the level of the neural membrane. Here, we propose a paradigm to study same-polarity summation of currents while keeping the stimulation charge-balanced within a short time windo

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47

Tofil, Szymon, Hubert Danielewski, Grzegorz Witkowski, Krystian Mulczyk, and Bogdan Antoszewski. "Technology and Properties of Peripheral Laser-Welded Micro-Joints." Materials 14, no. 12 (June 10, 2021): 3213. http://dx.doi.org/10.3390/ma14123213.

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This article presents the results of research on the technology and peripheral properties of laser-welded micro-couplings. The aim of this research was to determine the characteristics of properly made joints and to indicate the range of optimal parameters of the welding process. Thin-walled AISI 316L steel pipes with diameters of 1.5 and 2 mm used in medical equipment were tested. The micro-welding process was carried out on a SISMA LM-D210 Nd:YAG laser. The research methods used were macroscopic and microscopic analyses of the samples, and assessment of the distribution of elements in the we

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48

Lo, Fu-Sun, and Reha S. Erzurumlu. "Peripheral nerve damage does not alter release properties of developing central trigeminal afferents." Journal of Neurophysiology 105, no. 4 (April 2011): 1681–88. http://dx.doi.org/10.1152/jn.00833.2010.

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The infraorbital branch of the trigeminal nerve (ION) is essential in whisker-specific neural patterning (“barrelettes”) in the principal nucleus of the trigeminal nerve (PrV). The barrelettes are formed by the ION terminal arbors, somata, and dendrites of the PrV cells; they are abolished after neonatal damage to the ION. Physiological studies show that disruption of the barrelettes is accompanied by conversion of functional synapses into silent synapses in the PrV. In this study, we used whole cell recordings with a paired-pulse stimulation protocol and MK-801 blocking rate to estimate the p

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49

Connaughton, M. A., M. L. Fine, and M. H. Taylor. "The effects of seasonal hypertrophy and atrophy on fiber morphology, metabolic substrate concentration and sound characteristics of the weakfish sonic muscle." Journal of Experimental Biology 200, no. 18 (September 1, 1997): 2449–57. http://dx.doi.org/10.1242/jeb.200.18.2449.

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Male weakfish Cynoscion regalis possess highly specialized, bilateral, striated sonic muscles used in sound production associated with courtship. Androgen-driven hypertrophy of the muscles during the late spring spawning period results in a tripling of sonic muscle mass followed by post-spawning atrophy. This study examined the morphological and biochemical changes underlying seasonal changes in sonic muscle mass and the functional effects of these on contraction as measured by sound production. Sonic muscle fiber cross-sectional area (CSA) increased significantly during the period of hypertro

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50

Ritzel, R. A., J. D. Veldhuis, and P. C. Butler. "The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure." American Journal of Physiology-Endocrinology and Metabolism 290, no. 4 (April 2006): E750—E756. http://dx.doi.org/10.1152/ajpendo.00381.2005.

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Insulin is secreted in discrete insulin secretory bursts. Regulation of insulin release is accomplished almost exclusively by modulation of insulin pulse mass, whereas the insulin pulse interval remains stable at ∼4 min. It has been reported that in vivo insulin pulses can be entrained to a pulse interval of ∼10 min by infused glucose oscillations. If oscillations in glucose concentration play an important role in the regulation of pulsatile insulin secretion, abnormal or absent glucose oscillations, which have been described in type 2 diabetes, might contribute to the defective insulin secret

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