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Journal articles on the topic 'Peripheral veno-arterial ECMO'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

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1

Biancari, Fausto, Alexander Kaserer, Andrea Perrotti, et al. "Central versus Peripheral Postcardiotomy Veno-Arterial Extracorporeal Membrane Oxygenation: Systematic Review and Individual Patient Data Meta-Analysis." Journal of Clinical Medicine 11, no. 24 (2022): 7406. http://dx.doi.org/10.3390/jcm11247406.

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Background: It is unclear whether peripheral arterial cannulation is superior to central arterial cannulation for postcardiotomy veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods: A systematic review was conducted using PubMed, Scopus, and Google Scholar to identify studies on postcardiotomy VA-ECMO for the present individual patient data (IPD) meta-analysis. Analysis was performed according to the intention-to-treat principle. Results: The investigators of 10 studies agreed to participate in the present IPD meta-analysis. Overall, 1269 patients were included in the analysis

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Rao, Prashant, Jarrod Mosier, Joshua Malo, et al. "Peripheral VA-ECMO with direct biventricular decompression for refractory cardiogenic shock." Perfusion 33, no. 6 (2018): 493–95. http://dx.doi.org/10.1177/0267659118761558.

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Cardiogenic shock and cardiac arrest are life-threatening emergencies that result in high mortality rates. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) via peripheral cannulation is an option for patients who do not respond to conventional therapies. Left ventricular (LV) distention is a major limitation with peripheral VA-ECMO and is thought to contribute to poor recovery and the inability to wean off VA-ECMO. We report on a novel technique that combines peripheral VA-ECMO with off-pump insertion of a trans-apical LV venting cannula and a right ventricular decompression cannula

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3

Blandino Ortiz, Aaron, Mirko Belliato, Lars Mikael Broman, et al. "Early Findings after Implementation of Veno-Arteriovenous ECMO: A Multicenter European Experience." Membranes 11, no. 2 (2021): 81. http://dx.doi.org/10.3390/membranes11020081.

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Extracorporeal membrane oxygenation (ECMO) is increasingly used to treat cardiopulmonary failure in critically ill patients. Peripheral cannulation may be complicated by a persistent low cardiac output in case of veno-venous cannulation (VV-ECMO) or by differential hypoxia (e.g., lower PaO2 in the upper than in the lower body) in case of veno-arterial cannulation (VA-ECMO) and severe impairment of pulmonary function associated with cardiac recovery. The treatment of such complications remains challenging. We report the early effects of the use of veno-arterial-venous (V-AV) ECMO in this settin

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4

Andrei, Stefan, Maxime Nguyen, Vivien Berthoud, et al. "Determinants of Arterial Pressure of Oxygen and Carbon Dioxide in Patients Supported by Veno-Arterial ECMO." Journal of Clinical Medicine 11, no. 17 (2022): 5228. http://dx.doi.org/10.3390/jcm11175228.

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Background: The present study aimed to assess the determinants of arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2) in the early phase of veno-arterial extracorporeal membrane oxygenation (VA ECMO) support. Even though the guidelines considered both the risks of hypoxemia and hyperoxemia during ECMO support, there are a lack of data concerning the patients supported by VA ECMO. Methods: This is a retrospective, monocentric, observational cohort study in a university-affiliated cardiac intensive care unit. Hemodynamic parameters, ECMO parameters, ventilator settings, and blo

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5

Rodriguez, Maria L., and Gyaandeo Maharajh. "Long venous cannula on the arterial position for VA-ECMO." Perfusion 33, no. 6 (2018): 423–25. http://dx.doi.org/10.1177/0267659118765628.

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Differential hypoxia and the arterial mixing zone are two important factors in managing peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO). With the aim of improving perfusion to the aortic arch branches and coronaries, we describe our approach for VA-ECMO cannulation: bicaval drainage through the femoral vein and proximal retrograde ECMO flow using a multi-stage venous cannula inserted in the femoral artery and the tip placed at the proximal descending thoracic aorta. We report the use of this VA-ECMO approach on a 15-year-old female with combined cardiorespiratory failure

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6

Moroz, G. B., D. A. Sirota, A. V. Guseva, A. V. Fomichev, and E. E. Kliver. "Use of cryopreserved aortic homograft for subclavian arterial cannulation during extracorporeal membrane oxygenation." Russian Journal of Transplantology and Artificial Organs 27, no. 1 (2024): 84–89. https://doi.org/10.15825/1995-1191-2025-1-84-89.

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Extracorporeal membrane oxygenation (ECMO) is a vital tool in the treatment of patients with severe cardiovascular failure during heart surgery. The femoral artery is the most common access for veno-arterial ECMO in adults. Where there are contraindications to traditional cannulation techniques, the subclavian artery is an alternative access site, despite its many peculiarities. This paper presents a clinical case where peripheral ECMO connection with cannulation into the subclavian artery using a cryopreserved homovital abdominal aortic homograft was performed in a patient.

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Chang, Hsiao-Huang, Kai-Hsiang Hou, Ting-Wei Chiang, Yi-Min Wang, and Chia-Wei Sun. "Using Signal Features of Functional Near-Infrared Spectroscopy for Acute Physiological Score Estimation in ECMO Patients." Bioengineering 11, no. 1 (2023): 26. http://dx.doi.org/10.3390/bioengineering11010026.

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Extracorporeal membrane oxygenation (ECMO) is a vital emergency procedure providing respiratory and circulatory support to critically ill patients, especially those with compromised cardiopulmonary function. Its use has grown due to technological advances and clinical demand. Prolonged ECMO usage can lead to complications, necessitating the timely assessment of peripheral microcirculation for an accurate physiological evaluation. This study utilizes non-invasive near-infrared spectroscopy (NIRS) to monitor knee-level microcirculation in ECMO patients. After processing oxygenation data, machine

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8

Weber, Carolyn, Antje-Christin Deppe, Anton Sabashnikov, et al. "Left ventricular thrombus formation in patients undergoing femoral veno-arterial extracorporeal membrane oxygenation." Perfusion 33, no. 4 (2017): 283–88. http://dx.doi.org/10.1177/0267659117745369.

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Introduction: Profoundly impaired left ventricular (LV) function in patients undergoing femoral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) can result in intra-cardiac stasis and thrombus formation. There have been several attempts to improve LV unloading in patients with peripheral VA-ECMO, either by improving contractility or by venting the LV. Methods: Data from all patients who underwent femoral VA-ECMO between 2007 and 2015 due to cardiogenic decompensation were retrospectively analysed regarding intra-cardiac thrombus formation. Results: In total, 11 of 281 patients (3.

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Simons, Jorik, Sandra Agricola, Jeroen Smets, et al. "Duplex Analysis of Cannulated Vessels in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation." Medicina 58, no. 5 (2022): 671. http://dx.doi.org/10.3390/medicina58050671.

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Background and objectives: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) cannulas have major repercussions on vascular hemodynamics that can potentially lead to limb ischemia. Duplex ultrasound enables the non-invasive analysis of vascular hemodynamics. This study aims to describe the duplex parameters of the femoral vessels during V-A ECMO support, investigate differences between cannulated and non-cannulated vessels, and analyze the variations in the case of limb ischemia and intra-aortic balloon pumps (IABPs). Methods: Nineteen adults (≥18 years), supported with femoro-femora

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10

Spirina, E. A., R. S. Saitgareev, D. V. Shumakov, et al. "PERIPHERAL VENO-ARTERIAL ECMO AS MECHANICAL CIRCULATORY SUPPORT BEFORE HEART TRANSPLANTATION." Russian Journal of Transplantology and Artificial Organs 15, no. 2 (2014): 23. http://dx.doi.org/10.15825/1995-1191-2013-2-23-35.

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11

Meani, Paolo, Thijs Delnoij, Giuseppe M. Raffa, et al. "Protracted aortic valve closure during peripheral veno-arterial extracorporeal life support: is intra-aortic balloon pump an effective solution?" Perfusion 34, no. 1 (2018): 35–41. http://dx.doi.org/10.1177/0267659118787426.

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Background: Left ventricular (LV) afterload increase with protracted aortic valve (AV) closure may represent a complication of veno-arterial extracorporeal membrane oxygenation (V-A ECMO). The aim of the present study was to assess the effects of an intra-aortic balloon pump (IABP) to overcome such a hemodynamic shortcoming in patients submitted to peripheral V-A ECMO. Methods: Among 184 adult patients who were treated with peripheral V-A ECMO support at Medical University Center Maastricht Hospital between 2007 and 2018, patients submitted to IABP implant for protracted AV closure after V-A E

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Brockaert, Tifanie, Inês Ferreira, Anne Laplante, Paul Fogel, David Grimbert, and Pierre Mordant. "Preventing Acute Limb Ischemia during VA-ECMO—In Silico Analysis of Physical Parameters Associated with Lower Limb Perfusion." Journal of Clinical Medicine 12, no. 18 (2023): 6049. http://dx.doi.org/10.3390/jcm12186049.

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Background: Peripheral femoro-femoral veno-arterial extracorporeal membrane oxygenation is increasingly used in refractory cardiogenic shock. However, the obstruction of the femoral artery by the return cannula could lead to acute limb ischemia, a frequently encountered situation that is inconstantly prevented by the adjunction of a distal perfusion cannula (DPC). The aim of this study was to investigate the influence of three physical parameters on the perfusion of the cannulated lower limb. Methods: Using patient-specific arterial models and computational fluid dynamic simulations, we studie

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13

Efrimescu, Catalin Iulian, Don M. Walsh, Jehan Zeb Chughtai, and Thomas P. Wall. "Preoperative initiation of peripheral veno-arterial extracorporeal membrane oxygenation for a complex case of cardiac tamponade." BMJ Case Reports 16, no. 9 (2023): e253913. http://dx.doi.org/10.1136/bcr-2022-253913.

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In this case report, we present an alternative approach to the anaesthetic management of patients presenting with delayed postoperative cardiac tamponade physiology. Given that pericardiocentesis was deemed unsafe, and a protracted surgical dissection was anticipated, peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support was established prior to induction of anaesthesia to prevent catastrophic circulatory failure. To the best of our knowledge, this is the first reported case of planned preoperative commencement of peripheral VA-ECMO in a complex case of cardiac tampona

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14

Djordjevic, Ilija, Oliver Liakopoulos, Mara Elskamp, et al. "Concomitant Intra-Aortic Balloon Pumping Significantly Reduces Left Ventricular Pressure during Central Veno-Arterial Extracorporeal Membrane Oxygenation—Results from a Large Animal Model." Life 12, no. 11 (2022): 1859. http://dx.doi.org/10.3390/life12111859.

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(1) Introduction: Simultaneous ECMO and IABP therapy is frequently used. Haemodynamic changes responsible for the success of the concomitant mechanical circulatory support system approach are rarely investigated. In a large-animal model, we analysed haemodynamic parameters before and during ECMO therapy, comparing central and peripheral ECMO circulation with and without simultaneous IABP support. (2) Methods: Thirty-three female pigs were divided into five groups: (1) SHAM, (2) (peripheral)ECMO(–)IABP, (3) (p)ECMO(+)IABP, (4) (central)ECMO(–)IABP, and (5) (c)ECMO(+)IABP. Pigs were cannulated i

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Torre, Debora Emanuela, Domenico Mangino, and Carmelo Pirri. "Veno-Arterial Extracorporeal Membrane Oxygenation in Cardiotoxic Drug-Induced Cardiogenic Shock: A Systematic Narrative Review." Life 15, no. 6 (2025): 925. https://doi.org/10.3390/life15060925.

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Background: Severe poisoning can lead to catastrophic cardiovascular collapse, often progressing to multiorgan failure and death. While intensive supportive care and pharmacological intervention remain the cornerstone of management, cases of refractory cardiogenic shock, particularly those caused by membrane stabilizing agents and calcium channel blockers, pose a significant therapeutic challenge. Extracorporeal membrane oxygenation (ECMO) has emerged as a potential life-saving intervention in critically ill patients. This review examines the feasibility, clinical outcomes, and optimal indicat

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16

Capoccia, Massimo, Joseph M. Brewer, Mindaugas Rackauskas, et al. "Outcome of Veno-Pulmonary Extracorporeal Life Support in Lung Transplantation Using ProtekDuo Cannula: A Systematic Review and Description of Configurations." Journal of Clinical Medicine 13, no. 14 (2024): 4111. http://dx.doi.org/10.3390/jcm13144111.

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Background: Refractory end-stage pulmonary failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) has been recommended for patients who have failed conventional medical therapy and mechanical ventilation. Veno-arterial (VA) ECMO may be used in patients with acute right ventricular (RV) failure, haemodynamic instability, or refractory respiratory failure. Peripheral percutaneous approaches, either dual-site single-lumen cannulation for veno-pulmonary (VP) ECMO or single-site dual-lumen (dl)VP E

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17

Shugh, Svetlana B., Sebastian C. Tume, Neha Bansal, et al. "Transcatheter Axial Pump Use in Pediatric Patients on Veno-Arterial Extracorporeal Membrane Oxygenation: An ACTION Collaborative Experience." ASAIO Journal 70, no. 7 (2024): 602–8. http://dx.doi.org/10.1097/mat.0000000000002150.

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We report the largest pediatric multicenter experience with Impella pump use and peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support. Utilizing the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) collaborative database, we conducted a retrospective, multicenter study of all patients with cardiogenic shock requiring VA-ECMO support with subsequent Impella implant between October 2014 and December 2021. The primary outcome was defined as death while on Impella support. Secondary outcomes were recovery, transplantation, and transition to durable ventricul

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18

Kang, Soyoung, Seungwon Yang, Jongsung Hahn, et al. "Dose Optimization of Meropenem in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation in Critically Ill Cardiac Patients: Pharmacokinetic/Pharmacodynamic Modeling." Journal of Clinical Medicine 11, no. 22 (2022): 6621. http://dx.doi.org/10.3390/jcm11226621.

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Background: Our objective was to determine an optimal dosage regimen of meropenem in patients receiving veno-arterial extracorporeal membrane oxygenation (V-A ECMO) by developing a pharmacokinetic/pharmacodynamic (PK/PD) model. Methods: This was a prospective cohort study. Blood samples were collected during ECMO (ECMO-ON) and after ECMO (ECMO-OFF). The population pharmacokinetic model was developed using nonlinear mixed-effects modeling. A Monte Carlo simulation was used (n = 10,000) to assess the probability of target attainment. Results: Thirteen adult patients on ECMO receiving meropenem w

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Poptsov, Vitaly, Ekaterina Spirina, Anastasiya Dogonasheva, and Elizaveta Zolotova. "Five years’ experience with a peripheral veno-arterial ECMO for mechanical bridge to heart transplantation." Journal of Thoracic Disease 11, S6 (2019): S889—S901. http://dx.doi.org/10.21037/jtd.2019.02.55.

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20

Poptsov, V. N., E. A. Spirina, R. S. Saitgareev, V. M. Zakharevich, O. A. Eremeeva, and S. A. Masyutin. "Peripheral Veno-Arterial ECMO as a Bridge To Heart Transplantation: Outcomes From a Single-Centre Experience." Journal of Heart and Lung Transplantation 33, no. 4 (2014): S247—S248. http://dx.doi.org/10.1016/j.healun.2014.01.647.

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21

Baran, Cagdas, Evren Ozcinar, Ahmet Kayan, Nur Dikmen, Canan Soykan Baran, and Mustafa Bahadir Inan. "Comparison of ECMO, IABP and ECMO + IABP in the Postoperative Period in Patients with Postcardiotomy Shock." Journal of Cardiovascular Development and Disease 11, no. 9 (2024): 283. http://dx.doi.org/10.3390/jcdd11090283.

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Background: This study aims to assess the outcomes and complications of patients who received veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and intra-aortic balloon pump (IABP) support after cardiac surgery at Ankara University Heart Center between 2000 and 2023. Methods: We have carried out a retrospective analysis that included 255 patients. Among them, 98 received IABP, 103 received VA-ECMO, and 54 received both VA-ECMO and IABP. Preoperative and postoperative assessments were carried out, including evaluations of left ventricular function and serum creatinine levels. Primary

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Poptsov, V. N., V. M. Zakharevich, E. A. Spirina, et al. "Strategy for prophylactic application of peripheral va-ecmo in transplantation involving expected extremely prolonged ischemia time." Russian Journal of Transplantology and Artificial Organs 26, no. 1 (2023): 55–66. http://dx.doi.org/10.15825/1995-1191-2024-1-55-66.

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Heart transplantation (HT) with extremely prolonged (>6 hours) graft ischemia is associated with severe cardiac graft dysfunction. The high efficiency of prophylactic (preoperative initiation) veno-arterial extracorporeal membrane oxygenation (VA-ECMO) to prevent severe hemodynamic disorders during cardiac surgery has been demonstrated. Objective: to determine the effect of prophylactic VA-ECMO on the perioperative period in HT with an expected graft ischemia >6 hours. Materials and methods. Thirty-eight recipients (33 (86.8%) males and 5 (13.2%) females), age 11–66 (44.7 ± 12.0) years (

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23

Centofanti, Paolo, Matteo Attisani, Michele La Torre, et al. "Left Ventricular Unloading during Peripheral Extracorporeal Membrane Oxygenator Support: A Bridge To Life In Profound Cardiogenic Shock." Journal of ExtraCorporeal Technology 49, no. 3 (2017): 201–5. http://dx.doi.org/10.1051/ject/201749201.

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A limit of peripheral veno-arterial Extracorporeal Membrane Oxigenator (VA-ECMO) is the inadequate unloading of the left ventricle. The increase of end-diastolic pressure reduces the possibility of a recovery and may cause severe pulmonary edema. In this study, we evaluate our results after implantation of VA-ECMO and Transapical Left Ventricular Vent (TLVV) as a bridge to recovery, heart transplantation or long-term left ventricular assit devices (LVAD). From 2011 to 2014, 24 consecutive patients with profound cardiogenic shock were supported by peripheral VA-ECMO as bridge to decision. In al

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Poptsov, V. N., V. M. Zakharevich, E. A. Spirina, S. G. Uhrenkov, A. A. Dogonasheva, and E. Z. Aliev. "Outcomes and risk factors of mechanical circulatory support by peripheral venoarterial extracorporeal membrane oxygenation in heart transplant candidates needing urgent heart transplantation." Russian Journal of Transplantology and Artificial Organs 19, no. 4 (2018): 54–60. http://dx.doi.org/10.15825/1995-1191-2017-4-54-60.

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Introduction Peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) is one of the most frequently used methods of temporary mechanical circulatory support (MCS) at patients with life-threatening circulatory derangement.Aim: to evaluate the effectiveness and risk factors of peripheral VA ECMO in patients waiting of urgent heart transplantation (HT). Materials and methods. The study included 149 (129 (86.6%) men and 20 (13.4%) women, age 12 to 72 (43.0 ± 1.2) years) heart transplant candidates who in the period 01.01.2011–31.12.2016 were supported by peripheral VA ECMO. These pat

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Baran, Cagdas, Evren Ozcinar, Ahmet Kayan, et al. "Vascular Complications in Patients with ECMO Support after Cardiac Surgery." Journal of Clinical Medicine 13, no. 17 (2024): 5055. http://dx.doi.org/10.3390/jcm13175055.

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Background: This study assessed vascular complications in patients who received extracorporeal membrane support following cardiac surgery. Methods: We included 84 post-cardiotomy patients who underwent extracorporeal membrane oxygenation (ECMO) from July 2018 to May 2022. Only patients connected to VA-ECMO (Veno-Arterial) via peripheral cannulation were included in this study. Vascular complications were compared between those who had ECMO placed using the percutaneous technique (n = 52) and those who had it placed via femoral incision (n = 32). Results: The incidence of vascular thromboemboli

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Poptsov, V. N., E. A. Spirina, and A. A. Dogonascheva. "Five Years Experience of Peripheral Veno-Arterial ECMO as Method of Mechanical Circulatory Support in Heart Transplant Candidates." Journal of Heart and Lung Transplantation 39, no. 4 (2020): S14. http://dx.doi.org/10.1016/j.healun.2020.01.1135.

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27

Loforte, A., B. Parrella, A. Spitaleri, et al. "EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT AS TREATMENT FOR CARDIOGENIC SHOCK: TREATMENT STRATEGIES AND ANALYSIS OF RISK FACTORS." Journal of Cardiovascular Medicine 25, Supplement 1 (2024): e17. https://doi.org/10.2459/01.jcm.0001096316.79311.28.

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Background and Aim: RotaFlow and CardioHelp (Getinge), used in central (c-) or peripheral (p-) veno-arterial (VA) extra-corporeal membrane oxygenation (ECMO) support systems have been investigated as treatment for patients with cardiogenic shock (CS). Methods: Between 2005 and 2024, 359 consecutive adult patients were supported on VA ECMO, at our institution (239 men; age 55.1±14.2 years). Indications for support were: failure to wean from cardiopulmonary bypass in the setting of post-cardiotomy (n=134) and primary donor graft failure (n=39); post-acute myocardial infarction CS (n=79); acute m

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28

Poptsov, V. N., E. A. Spirina, A. K. Solodovnikova, et al. "Heart transplantation in patients undergoing extracorporeal cardiopulmonary resuscitation in in‑hospital cardiac arrest." Russian Journal of Transplantology and Artificial Organs 26, no. 4 (2024): 100–109. https://doi.org/10.15825/1995-1191-2024-4-100-109.

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Objective: to analyze heart transplant (HT) outcomes in patients who suffered cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR) by peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Materials and methods. The study included 41 patients (14 (34.1%) women and 27 (65.9%) men, aged 42.6 ± 16.8 (40.0 [30.5; 54.0]) years with in-hospital cardiac arrest. The causes of cardiac arrest were acute decompensated heart failure (n = 19; 46.3%), irreversible graft dysfunction (n = 9; 22.0%), postcardiotomy acute heart failure (n = 5; 12.2%), acute myocardial in

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Gerfer, Stephen, Ilija Djordjevic, Johanna Maier, et al. "Endothelial and Hemodynamic Function in a Large Animal Model in Relation to Different Extracorporeal Membrane Oxygenation Cannulation Strategies and Intra-Aortic Balloon Pumping." Journal of Clinical Medicine 12, no. 12 (2023): 4038. http://dx.doi.org/10.3390/jcm12124038.

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Background: The use of simultaneous veno-arterial extracorporeal membrane oxygenation (ECMO) with or without an Intra-Aortic Balloon Pump (IABP) is a widely used tool for mechanical hemodynamic support. Endothelial function, especially in relation to different cannulation techniques, is rarely investigated in the setting of extracorporeal life support (ECLS). In this study, we analyzed endothelial function in relation to hemodynamic and laboratory parameters for central and peripheral ECMO, with or without concomitant IABP support in a large animal model to gain a better understanding of the u

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Kulyassa, Péter, Balázs Tamás Németh, István Hartyánszky, et al. "A VA-ECMO használata, tapasztalatok a Városmajori Klinikán." Cardiologia Hungarica 51, no. 5-6 (2021): 320–30. http://dx.doi.org/10.26430/chungarica.2021.51.5.320.

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Mechanical circulatory support (MCS) was introduced in the 1960s, of which there is short-, mid- and long-term forms. This brief review discusses our experiences with the primary modality used in Hungary, the veno-arterial extracorporeal membrane oxygenator (VA-ECMO). We introduced the device with the most relevant information and summarized our clinic’s registry with patient characteristics and results in whom we applied this modality next to data of international studies. We collected data retro- and prospectively from 2012 to 2020 from patients treated with the VA-ECMO at our clinic. The p

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Harpa, Marius Mihai, Sânziana Flamind Oltean, Hussam Al Hussein, et al. "Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication—Case Presentation." Journal of Clinical Medicine 13, no. 24 (2024): 7654. https://doi.org/10.3390/jcm13247654.

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Background/Objectives: In recent decades, the advantages of minimizing surgical trauma have led to the development of minimally invasive surgical procedures. While the benefits often outweigh the risks, several challenges are encountered that are not present in conventional surgical approaches. Unilateral pulmonary edema (UPE) after mitral interventions performed through a right-sided approach is a rare but potentially life-threatening event. Methods: We present the case of a 49-year-old patient who underwent endoscopic mitral valve repair. Immediately following ICU admission, the patient’s ox

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Zhang, Li. "Near-infrared spectroscopy and ultrasound as complementary methods for assessing organ and peripheral tissue perfusion in veno-arterial-ECMO patients." American Journal of Translational Research 17, no. 4 (2025): 2629–41. https://doi.org/10.62347/uqys8766.

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Haertel, Franz, Thomas Lehmann, Tabitha Heller, et al. "Impact of a VA–ECMO in Combination with an Extracorporeal Cytokine Hemadsorption System in Critically Ill Patients with Cardiogenic Shock–Design and Rationale of the ECMOsorb Trial." Journal of Clinical Medicine 12, no. 15 (2023): 4893. http://dx.doi.org/10.3390/jcm12154893.

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Background: Cardiogenic shock and arrest present as critical, life-threatening emergencies characterized by severely compromised tissue perfusion and inadequate oxygen supply. Veno–arterial extracorporeal membrane oxygenation (VA–ECMO) serves as a mechanical support system for patients suffering shock refractory to conventional resuscitation. Despite the utilization of VA–ECMO, clinical deterioration due to systemic inflammatory response syndrome (SIRS) resulting from the underlying shock and exposure of blood cells to the artificial surfaces of the ECMO circuit may occur. To address this issu

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Zeymer, Uwe, and Dirk Westermann. "Veno-arterial extracorporeal membrane oxygenation." Current Opinion in Critical Care, June 13, 2025. https://doi.org/10.1097/mcc.0000000000001295.

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Purpose of review Despite improvements in reperfusion and adjunctive therapies cardiogenic shock associated with acute myocardial infarction is still associated with a mortality of 40–50%. Therefore, mechanical circulatory support devices are increasingly used. One option is veno-arterial extracorporal membrane oxygenation (VA-ECMO). VA-ECMO can be implanted percutaneously and blood is actively pumped into a tubing system outside the body which also incorporates an artificial lung for oxygenation and removal of carbon dioxide and then sent back retrograde in the aorta. This review summarizes t

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Winiszewski, Hadrien, Pierre-Grégoire Guinot, Matthieu Schmidt, et al. "Optimizing PO2 during peripheral veno-arterial ECMO: a narrative review." Critical Care 26, no. 1 (2022). http://dx.doi.org/10.1186/s13054-022-04102-0.

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AbstractDuring refractory cardiogenic shock and cardiac arrest, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is used to restore a circulatory output. However, it also impacts significantly arterial oxygenation. Recent guidelines of the Extracorporeal Life Support Organization (ELSO) recommend targeting postoxygenator partial pressure of oxygen (PPOSTO2) around 150 mmHg. In this narrative review, we intend to summarize the rationale and evidence for this PPOSTO2 target recommendation. Because this is the most used configuration, we focus on peripheral VA-ECMO. To date, clinicians

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Göbölös, Laszlo, Maurice Hogan, Vivek Kakar, et al. "Alternative option for limb reperfusion cannula placement for percutaneous femoral veno-arterial ECMO." Perfusion, March 26, 2021, 026765912110032. http://dx.doi.org/10.1177/02676591211003282.

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Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is an established last line support for severe, acute cardiorespiratory failure. In the case of VA ECMO, peripheral cannulation via the femoral vessels is often advantageous when compared with the alternative central cannulation, and is associated with better clinical outcomes. One of the specific potential complications of peripheral femoral arterial cannulation for ECMO, however, is ipsilateral distal lower limb ischemia; a consideration especially when cannulating the vessel directly, as distal limb perfusion is invariably compromi

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Pirompanich, Pattarin, Napakul Patiyakul, Kiattichai Daorattanachai, Boonlawat Homvises, and Pichaya Tantiyavarong. "Clinical characteristics and outcomes of adults with peripheral extracorporeal membrane oxygenation in a developing country: A single center 8-year retrospective study." Perfusion, December 16, 2020, 026765912098037. http://dx.doi.org/10.1177/0267659120980376.

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Introduction: In our institute, we began using peripheral veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) in 2010, and peripheral veno-venous (VV) ECMO in 2015. This study aimed to describe clinical characteristics and outcomes in those patients. Methods: We reviewed retrospective data of adults receiving peripheral ECMO from January 2010 to December 2017 and divided it into two groups for analysis: VA- and VV-ECMO. Results: There were 28 patients in the VA group and 12 in VV. For VA, the mean (SD) age was 58.5 (17.2) years. The most common indication was cardiac arrest (12 patie

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Kalampokas, Nikolaos, Nihat Firat Sipahi, Hug Aubin, et al. "Postcardiotomy Veno-Arterial Extracorporeal Membrane Oxygenation: Does the Cannulation Technique Influence the Outcome?" Frontiers in Cardiovascular Medicine 8 (August 9, 2021). http://dx.doi.org/10.3389/fcvm.2021.658412.

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Objectives: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may be cannulated using either central (cannulation of aorta) or peripheral (cannulation of femoral or axillary artery) access. The ideal cannulation approach for postcardiotomy cardiogenic shock (PCS) is still unknown. The aim of this study is to compare the outcome of patients with PCS who were supported with central vs. peripheral cannulation.Methods: This is a single-center retrospective data analysis including all VA-ECMO implantations for PCS from January 2011 to December 2017. The central and peripheral approaches w

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Gobolos, Laszlo, Maurice Hogan, Vivek Kakar, et al. "Abstract 16853: Retrograde Peripheral Limb Perfusion for Formidable Femoral Arterial Access in Veno-Arterial ECMO Treatment." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.16853.

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Introduction: VA ECMO has emerged to a well-established therapeutic method in severe acute heart failure. In the case of peripheral ECMO placement, especially applying direct arterial cannulation, the limb perfusion is often compromised by an occlusive effect of the cannula positioned in the femoral artery. The classical proximal femoral arterial reperfusion branch provides sufficient blood flow via a small auxiliary cannula, but in patients with severe peripheral arterial vasculopathy or with significant tissue depth resulting from obesity, the placement of a peripheral arterial perfusion loo

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Trieu, Ngan Hoang Kim, Huy Minh Pham, Dai Quang Huynh, et al. "Peripheral VA-ECMO: from Evolving Indications to Perioperative Implications." Anesthesiology and Perioperative Science 3, no. 2 (2025). https://doi.org/10.1007/s44254-025-00106-5.

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Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a form of extracorporeal circulation that provides cardiopulmonary support in cardiogenic shock unresponsive to conventional therapy. Historically, VA-ECMO was limited to the operating room and primarily used to manage postcardiotomy cardiogenic shock cases. However, with advances in ECMO technology and a better understanding of patient selection criteria, VA-ECMO has expanded its role as a temporary and adaptable intervention in cardiogenic shock of diverse etiologies. This review provides an updated overview of the indic

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Warnock, Brielle, Gina Maria Lafferty, Abdelaziz Farhat, Cameron Colgate, Archana Dhar, and Brian Gray. "Peripheral Veno-Arterial-Extracorporeal Membrane Oxygenation for Refractory Septic Shock in Children: A Multicenter Review." Journal of Intensive Care Medicine, October 29, 2023. http://dx.doi.org/10.1177/08850666231193357.

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Background Extracorporeal membrane oxygenation (ECMO) is utilized as a rescue therapy in the management of pediatric patients with refractory septic shock. Multiple studies support the use of a central cannulation strategy in these patients. This study aimed to assess the survival of and identify mortality risk factors in pediatric patients supported with peripheral veno-arterial (VA) ECMO in the setting of septic shock. Methods We retrospectively reviewed and compared clinical characteristics of 40 pediatric patients supported with peripheral VA ECMO for refractory septic shock, at two tertia

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Ng, Pauline Yeung, Sin Kwan Tammy Ma, April Ip, et al. "Abstract 10117: Reactivity Of Myocardial Contractility To Afterload Effects During Peripheral Veno-arterial Extracorporeal Membrane Oxygenation." Circulation 144, Suppl_1 (2021). http://dx.doi.org/10.1161/circ.144.suppl_1.10117.

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Introduction: Peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) poses increased afterload to the injured heart. The reactivity of myocardial contractility to ECMO blood flow during various phases of acute myocardial dysfunction has not been examined. Hypothesis: We hypothesized that myocardial contractility is more reactive to the afterload effects of peripheral V-A ECMO during the acute stage of myocardial dysfunction. Methods: Adult patients who were supported by peripheral V-A ECMO between April 2019 and October 2020 were recruited. Serial hemodynamic and cardiac perfo

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Shen, Ying-ying, Zhi-rong Zhang, Wen Feng, et al. "Improved remote infusion catheter for prevention of acute limb ischemia in peripheral veno-arterial extracorporeal membrane oxygenation." Discover Medicine 1, no. 1 (2024). http://dx.doi.org/10.1007/s44337-024-00033-7.

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AbstractThis is an application of an improved remote infusion catheter in femoral artery veno-arterial extracorporeal membrane oxygenation (VA ECMO). VA ECMO is a critical technique for treating cardiogenic shock and cardiac arrest. However, acute limb ischemia has emerged as a severe complication of this treatment method, potentially significantly impacting patient prognosis and survival rates. We propose a modified remote infusion catheter method that utilizes a double male luer-lock connector to directly connect to the arterial sheath. This aims to address certain issues present in current

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Paulo, Nicolas, Antoine Kimmoun, David Hajage, et al. "Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis." Annals of Intensive Care 15, no. 1 (2025). https://doi.org/10.1186/s13613-025-01457-9.

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Abstract Background Preliminary evidence from small, single-center studies suggests levosimendan may improve the likelihood of successful venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in patients with cardiogenic shock. However, the literature is limited and presents conflicting results. We aimed to assess the benefits of levosimendan on VA-ECMO for time to successful ECMO weaning, using a pragmatic and rigorous definition of successful VA-ECMO weaning in patients with potential for cardiac function recovery. Methods A retrospective bicentric study over 6 years was conduct

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Tantway, Tarek M., Amr A. Arafat, Monirah A. Albabtain, et al. "Sepsis in postcardiotomy cardiogenic shock patients supported with veno-arterial extracorporeal membrane oxygenation." International Journal of Artificial Organs, February 6, 2023, 039139882311529. http://dx.doi.org/10.1177/03913988231152978.

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Background: Sepsis could affect the outcomes of patients with postcardiotomy cardiogenic shock supported with extracorporeal membrane oxygenation (ECMO). Our objectives were to characterize sepsis patients with ECMO support for postcardiotomy cardiogenic shock and assess its predictors and effect on patients’ outcomes. Methods: This retrospective study included 103 patients with ECMO for postcardiotomy cardiogenic shock from 2009 to 2020. Patients were divided according to the occurrence and timing of sepsis into three groups. Group 1 included patients with no sepsis ( n = 67), Group 2 include

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Ng, Pauline Yeung, Tammy Sin Kwan Ma, April Ip, et al. "Effects of varying blood flow rate during peripheral veno-arterial extracorporeal membrane oxygen (V-A ECMO) on left ventricular function measured by two-dimensional strain." Frontiers in Cardiovascular Medicine 10 (April 12, 2023). http://dx.doi.org/10.3389/fcvm.2023.1147783.

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BackgroundWe evaluated the effects of varying blood flow rate during peripheral veno-arterial extracorporeal membrane oxygen (V-A ECMO) on left ventricular function measured by two-dimensional strain.MethodsAdult patients who were supported by peripheral V-A ECMO were recruited. Serial hemodynamic and cardiac performance parameters were measured by transthoracic echocardiogram within the first 48 h after implementation of V-A ECMO. Measurements at 100%, 120%, and 50% of target blood flow (TBF) were compared.ResultsA total of 54 patients were included and the main indications for V-A ECMO were

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Hammad, Waheed, Moustafa Younis, Hala Almajali, Zaineh Alfreahat, Salem Alsalman, and Yasmeen Alabdallat. "Veno-Arterial Extracorporeal Membrane Oxygenation in Pregnancy: A Literature Review." JAP Academy Journal 2, no. 1 (2024). http://dx.doi.org/10.58877/japaj.v2i1.193.

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Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a very important circulatory support system, and its use is increasing over the years especially in pregnancy and its related consequences on the mother and the fetus. This article is directed to review all the important aspects regarding VA-ECMO in pregnancy, addressing that it is less commonly used during pregnancy not disregarding maternal, neonatal, and long-term outcomes such as, the survival rate is relatively good compared to the general population adjusted to different causes mentioned in this article. A description of what

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"Hospital outcomes after emergent peripheral veno-arterial extracorporeal membrane oxygenation in adult patients presenting with cardiogenic shock." Signa Vitae, 2021. http://dx.doi.org/10.22514/sv.2021.118.

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Background: Emergent peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been used frequently to support patients with refractory cardiogenic shock with variable rates of complications. We retrospectively analyzed adult patients who received peripheral VA-ECMO support between 2015 and 2019 at our tertiary care hospital. Results: Sixty five patients with a mean age of 37.9 ± 14.9 years, mostly males (70.8%), were supported with femoral VA-ECMO with a median duration of 8 (IQR: 3–40) days. Hospital mortality occurred in 29 (44.6%) patients. Complications included acute kid

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Lucia, Mazzoni, Azmoun Alexandre, Ramadan Ramzi, et al. "Exclusive percutaneous peripheral veno-arterial ECMO with distal reperfusion of homolateral limb." Journal of Cardiothoracic Surgery 10, S1 (2015). http://dx.doi.org/10.1186/1749-8090-10-s1-a260.

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Martin Paniagua, S., A. Onha, M. De Miguel Alava, et al. "Does sex matter in patients who need support with veno-arterial ECMO?" European Heart Journal: Acute Cardiovascular Care 14, Supplement_1 (2025). https://doi.org/10.1093/ehjacc/zuaf044.142.

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Abstract Introduction Veno-arterial extracorporeal membrane oxygenation support (VA-ECMO) is an effective therapy in refractory cardiogenic shock and cardiorespiratory arrest. Sex-related differences regarding presentation and outcomes are not well stablished in this scenario. Methods Descriptive, retrospective and single-center study that includes all patients who required VA-ECMO support between 2021 and 2023. The main objective was to compare clinical characteristics, evolution and mortality in both sexes. Results 78 patients were included: 79.5% men and 20.5% women, with a mean age of 61.2

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