Academic literature on the topic 'Peritumoral area'

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Journal articles on the topic "Peritumoral area"

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Tabacaru, Gigi, Simona Moldovanu, and Marian Barbu. "Algorithm for Analyzing the Microenvironment Surrounding Melanoma." SYSTEM THEORY, CONTROL AND COMPUTING JOURNAL 3, no. 2 (2023): 15–19. http://dx.doi.org/10.52846/stccj.2023.3.2.52.

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Peritumoral areas or microenvironments surrounding melanoma are unexplored and partially understood, so that, in the following paper, an algorithm that predicts the trend of the melanoma progression is proposed. Additionally, in case of melanoma the peritumoral area is significantly correlated with the texture that belongs inside the skin lesion. The proposed algorithm analyses the region of interest (ROI) with Normalized 2-D cross-correlation (NCC) method and predicts the pattern in the peritumoral area which is most similar with the texture of the melanoma. An important step is the detection
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Ly, Ina, Barbara Wichtmann, Susie Yi Huang, et al. "Characterizing glioma microenvironment with ultra-high gradient diffusion MRI." Journal of Clinical Oncology 35, no. 15_suppl (2017): 2050. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2050.

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2050 Background: The infiltrating nature of gliomas, particularly into the peritumoral area, is a major barrier to improving clinical outcome as microscopic disease remains even after apparent gross total resection. Conventional T1 post-contrast and T2/FLAIR MRI do not capture full tumor extent. A better imaging biomarker is needed to improve differentiation between tumor, peritumoral area and normal brain. Methods: 4 pre-surgical patients with non-enhancing, FLAIR-hyperintense lesions suspicious for glioma underwent ultra-high gradient diffusion MRI on the Connectome MRI scanner, a unique sca
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Tatagiba, Marcos, Shahram Mirzai, and Madjid Samii. "Peritumoral Blood Flow in Intracranial Meningiomas." Neurosurgery 28, no. 3 (1991): 400–404. http://dx.doi.org/10.1227/00006123-199103000-00010.

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Abstract Blood flow was measured in intratumoral tissue, the cerebral hemispheres and particularly in the peritumoral area of 12 patients with intracranial meningiomas using the stable xenon-enhanced computed tomographic scan. Tumor blood flow frequently showed a heterogeneous pattern of enhancement with high flow at the tumor periphery and a central area of hypoperfusion. Blood flow values were on average 28% lower in the peritumoral area than in the ipsilateral cerebral hemisphere. In individual cases, blood flow values in the peritumoral edematous area were very low. These findings suggest
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Kumala Wardani, Bestia, Yuyun Yueniwati, and Agus Naba. "The Application of Image Segmentation to Determine the Ratio of Peritumoral Edema Area to Tumor Area on Primary Malignant Brain Tumor and Metastases through Conventional Magnetic Resonance Imaging." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 26–30. http://dx.doi.org/10.3889/oamjms.2022.7777.

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 BACKGROUND: Primary malignant brain tumor and metastases on the brain have a similar pattern in conventional Magnetic Resonance Imaging (MRI), even though both require entirely different treatment and management. The pathophysiological difference of peritumoral edema can help to distinguish the case of primary malignant brain tumor and brain metastases. 
 
 
 AIM: This study aimed to analyze the ratio of the area of peritumoral edema to the tumor using Otsu’s method of image segmentation technique with a user-friendly Graphical User Interface (GUI). 
 
 
 M
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Gao, Xiang, Haiyan Wang, Shanbao Cai, et al. "Phosphorylation of NMDA 2B at S1303 in human glioma peritumoral tissue: implications for glioma epileptogenesis." Neurosurgical Focus 37, no. 6 (2014): E17. http://dx.doi.org/10.3171/2014.9.focus14485.

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Object Peritumoral seizures are an early symptom of a glioma. To gain a better understanding of the molecular mechanism underlying tumor-induced epileptogenesis, the authors studied modulation of the N-methyl-d-aspartate (NMDA) receptor in peritumoral tissue. Methods To study the possible etiology of peritumoral seizures, NMDA receptor expression, posttranslational modification, and function were analyzed in an orthotopic mouse model of human gliomas and primary patient glioma tissue in which the peritumoral border (tumor-brain interface) was preserved in a tissue block during surgery. Results
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Carpenco, Ecaterina. "Tumor associated macrophages in breast cancer." Moldovan Medical Journal 62 (1) (March 15, 2019): 24–27. https://doi.org/10.5281/zenodo.2590003.

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<strong>Background: </strong>Cancer research was focused on the studying of proper tumor cells for a long time. Despite the huge progress, there are still a lot of questions, that&rsquo;s why new molecular markers must be identified. These could reveal new information about tumorigenesis. <strong>Material and methods: </strong>15 cases of ductal invasive breast carcinomas have been analyzed and researched on tumor associated macrophages via immunohistochemistry. CD68 was used as a macrophage marker and CD68<sup>+</sup> cells were evaluated in tumor nest and peritumoral area, as well as hormone
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Samani, Zahra Riahi, Drew Parker, Jacob Antony Alappatt, Steven Brem, and Ragini Verma. "NIMG-21. DIFFERENTIATING TUMOR TYPES BASED ON THE PERITUMORAL MICROENVIRONMENT USING CONVOLUTIONAL NEURAL NETWORKS." Neuro-Oncology 22, Supplement_2 (2020): ii151. http://dx.doi.org/10.1093/neuonc/noaa215.634.

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Abstract PURPOSE The differential diagnosis of glioblastoma (GBM) versus single brain metastasis (Met) is clinically important, and is undertaken with a clinical reading of MR images and/or tumor biopsy. We investigate whether Mets and GBMs can be differentiated based on the microstructure of the FLAIR-hyperintense peritumoral region measured by diffusion tensor imaging (DTI). We hypothesize that the peritumoral microstructure differs in extracellular water content, based on whether it is vasogenic edema or infiltrative. We use deep learning trained on DTI-based free-water volume fraction maps
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Danilova, N. V., V. M. Kkomyakov, A. V. Chayka, I. A. Mikhailov, N. A. Oleynikova, and P. G. Malkov. "CHARACTERISTICS OF THE IMMUNE MICROENVIRONMENT OF THE NORMAL MUCOUS MEMBRANE OF THE PERITUMORAL AREA IS AN ADDITIONAL INDEPENDENT PROGNOSTIC FACTOR IN GASTRIC CANCER." Siberian journal of oncology 20, no. 1 (2021): 74–86. http://dx.doi.org/10.21294/1814-4861-2021-20-1-74-86.

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The aim of the study was to study and evaluate the predictive value of the immune microenvironment of gastric cancer and morphologically normal mucous membrane of the peritumoral area using an automatic morphometric analysis system on the example of CD 8+ cells.Material and Methods. Surgical samples from 130 patients with a verified diagnosis of gastric cancer were used. After immunohistochemical staining with antibodies to CD 8, a morphological assessment was performed according to the original method. We assessed the average area of CD 8+ cells in three fields of view (lens magn. ×20) using
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Samani, Zahra Riahi, Drew Parker, Jacob Antony Alappatt, Steven Brem, and Ragini Verma. "NIMG-45. DEEP LEARNING-BASED PERITUMORAL MICROSTRUCTURE MAPPING IN GLIOBLASTOMAS USING FREE WATER VOLUME FRACTION." Neuro-Oncology 22, Supplement_2 (2020): ii157—ii158. http://dx.doi.org/10.1093/neuonc/noaa215.658.

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Abstract PURPOSE Characterization of the peritumoral microenvironment is a widely researched, but as yet unsolved problem. Determining the tissue microstructure differences between tumor types, arising from differences in infiltration, edema, and disease driven changes in cellularity is important to be able to guide treatment options. Diffusion tensor imaging with characterization of extracellular free water provides unique information of the tissue microstructure. The goal of this work is to leverage this information by applying deep learning on free water maps and create a microstructure map
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Monika Mehjabin, Abdus Sabur Talukder, Sabera sultana, Nure Jannat Ferdousi, Umme Kulsum Munmun, and Mohammed Kamal. "Prognostic Significance of Angiogenesis in invasive ductal carcinoma." Journal of Shaheed Suhrawardy Medical College 15, no. 1 (2024): 59–65. http://dx.doi.org/10.3329/jssmc.v15i1.76921.

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Background: Angiogenesis is essential for tumor growth and metastasis. Axillary lymphnode status has been the most important prognostic factor in operable breast carcinoma, but it does not fully account for the varied disease outcome. More accurate prognostic indicators would help in selection of patients at high risk for disease recurrence and death who are candidates for systemic adjuvant therapy. Microvessel density in invasive ductal carcinoma (measures of tumor angiogenesis) is associated with metastasis and thus may be a prognostic indicator. Objective: To correlate intratumoral and peri
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Dissertations / Theses on the topic "Peritumoral area"

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Michot, Audrey. "Projet PériSARC : identification de facteurs morphologiques et moléculaires prédictifs de rechute dans les sarcomes des tissus mous des membres et de la paroi du tronc." Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0239.

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Les sarcomes sont des tumeurs conjonctives malignes rares et représentent 2/100.000 nouveaux cas par an. Il s’agit d’un groupe hétérogène de tumeurs, généralement de mauvais pronostic. La chirurgie reste à ce jour le seul traitement curatif. Ces tumeurs peuvent récidiver même après une chirurgie considérée comme optimale, classée R0 c’est à dire sans reliquat microscopique (dans environ 10% des cas). Différents facteurs anatomocliniques pronostiques de rechute sont identifiés, incluant la taille tumorale initiale, le grade histologique FNCLCC et la localisation tumorale profonde. A l’heure act
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Ting, Yi-Cen, and 丁怡岑. "Microstructural Characterization in the Peritumoral Area of Glioma Patients and in the Corpus Callosum of Normal Subjects Using Neurite Orientation Dispersion and Density Imaging (NODDI)." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/hj8ra4.

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碩士<br>國立陽明大學<br>腦科學研究所<br>107<br>Diffusion magnetic resonance imaging (dMRI) is a technique for the non-invasive characterization of the microstructure in biological tissues since it is sensitive for the diffusion processes of hydrogen molecules. dMRI is a promising candidate for in vivo quantification of neurite morphology in white matter. Over the past two decades, conventional dMRI method usually focused on Diffusion Tensor Imaging (DTI). DTI was widely used to assess the organization of tissue in white matter, providing some indices to describe changes in biology. The model of DTI describe
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Books on the topic "Peritumoral area"

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Hatef, Jeffrey, and Russell R. Lonser. Hemangioblastoma. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190696696.003.0007.

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Hemangioblastomas are benign central nervous system tumors that are found primarily (99%) in the cerebellum, brainstem, and spinal cord. They can occur sporadically (67% of cases) or in the context of the familial neoplasia syndrome, von Hippel-Lindau disease (VHL; 33%). These lesions often remain quiescent or grow in a saltatory pattern. When these tumors cause signs or symptoms, the signs or symptoms are often associated with peritumoral cyst formation. Whether the tumor occurs sporadically or in the context of VHL, complete resection is the treatment of choice when necessary. This chapter d
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Woolf, Eric C., and Adrienne C. Scheck. Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer. Edited by Jong M. Rho. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0013.

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Malignant brain tumors are devastating, and increased survival requires new therapeutic modalities. Metabolic dysregulation results in an increased need for glucose in tumor cells, suggesting that reduced tumor growth could be achieved with decreased glucose availability either through pharmacological means or use of a high-fat, low-carbohydrate ketogenic diet (KD). KD provides increased blood ketones to support energy needs of normal tissues and has been shown to reduce tumor growth, angiogenesis, inflammation, peritumoral edema, migration, and invasion. Furthermore, this diet can enhance the
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Book chapters on the topic "Peritumoral area"

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Dai Duong, Ha, and Linh Duy Nguyen. "Glioma Resection in Functional Areas Using Diffusion Tensor Imaging-Based Tractography and Neuro-Navigation." In Advances in Neurosurgical Procedures - Unveiling New Horizons [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008995.

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Gliomas located in critical brain regions, such as the motor and language areas, present significant challenges in neurosurgery due to the elevated risk of causing neurological deficits during intervention. Diffusion tensor imaging (DTI)-based tractography has emerged as a valuable tool for both preoperative planning and intraoperative navigation, facilitating the identification of essential white matter tracts to help preserve functional integrity. This chapter provides a comprehensive overview of the application of DTI tractography combined with neuro-navigation in glioma resections within c
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Chassoux, Francine, Elisabeth Landré, and Bertrand Devaux. "Invasive EEG in Tumoural Epilepsy." In Invasive Studies of the Human Epileptic Brain, edited by Samden D. Lhatoo, Philippe Kahane, and Hans O. Lüders. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198714668.003.0016.

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Long-term epilepsy-associated tumours (LEATs) are usually dysembryoplastic neuroepithelial tumours (DNTs) and gangliogliomas. Both usually show childhood-onset intractable partial epilepsy, concordant focal EEG abnormalities, and predominant temporal location. Imaging showing typical pseudocystic pattern is suggestive of DNT. Gangliogliomas are characterized by association of a true cyst and nodular contrast enhancement. However, less typical patterns may also be seen, rendering differentiation between the two difficult. Stereo-EEG has demonstrated intrinsic epileptogenicity of both, the typic
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Scheck, Adrienne C., and Nelofer Syed. "Ketogenic Diet as Adjunctive Therapy for Malignant Brain Cancer." In Ketogenic Diet and Metabolic Therapies, edited by Susan A. Masino, Detlev Boison, Dominic P. D’Agostino, Eric H. Kossoff, and Jong M. Rho. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197501207.003.0015.

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Malignant brain tumors are devastating despite aggressive treatments, including surgical resection, chemotherapy, and radiation therapy. The average life expectancy of patients with newly diagnosed glioblastoma is approximately 18 months, and increased survival requires the design of new therapeutic modalities, especially those that enhance currently available treatments. One novel therapeutic arena is the metabolic dysregulation that results in an increased need for glucose in tumor cells. This phenomenon suggests that a reduction in tumor growth could be achieved by decreasing glucose availa
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Conference papers on the topic "Peritumoral area"

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Andrade, Danúbia Ariana de, Filomena Marino Carvalho, Fernando Nalesso Aguiar, Alfredo Luiz Jacomo, and Alfredo Carlos Simões Dornellas de Barros. "SIZE OF METASTATIC INFILTRATION IN THE SENTINEL NODE AS A PREDICTOR OF NON‑SENTINEL NODES INVOLVEMENT." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1065.

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Introduction: The broad acceptance of sentinel lymph node biopsy (SLNB) led to an analysis for finding out the anatomopathological characteristics that can help predict the involvement of other axillary lymph nodes (LN) in positive sentinel lymph node (SLN) cases. Currently, it is very appropriate to investigate the cases that enable the omission of complete axillary dissection (CAD), even considering the involvement of the SLN. Some important studies on this theme were published, e.g., ACOSOG Z0011, and AMAROS. However, their results were not accepted uniformly enough because of methodologica
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Sebiskveradze, David, Cyril Gobinet, Nathalie CARDOT-LECCIA, et al. "Abstract 4052: Highlighting intratumoral heterogeneity and peritumoral areas in human melanoma biopsies by infrared spectral microimaging." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4052.

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Rocha, Aline Carvalho. "Tumor-associated macrophages and their relationship with histopathological prognostic factors in breast cancer." In XXVI Brazilian Mastology Congress. Mastology, 2024. https://doi.org/10.29289/259453942024v34s2002.

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Introduction: The immune system plays a leading role in the tumor microenvironment due to the unique characteristics of its cells, such as macrophages, lymphocytes, among others. Tumor-associated macrophages (TAM) constitute up to 50% of the tumor mass in breast cancer and are vital to the innate immune response. Recently, numerous studies have been published evaluating the relationship between tumor-infiltrating lymphocytes (TILs) and TAMs in triple-negative breast tumors. High levels of TILs (CD8+ T cells) may be associated with a better prognosis, while high levels of TAMs are linked to poo
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Fonseca, Felipe Cordeiro, Eduardo Carvalho Pessoa, Carla Priscila Kamyia Pessoa, Benedito Sousa Almeida Filho, and Heloisa Maria De Luca Vespoli. "STUDY OF MORPHOLOGICAL AND ANGIOGENIC FEATURES OF TRIPLE NEGATIVE TUMORS BY ULTRASONOGRAPHY." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1012.

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Introduction: Since 2013, after the Saint Gallen International Breast Cancer Conference, breast cancer is classified by its morphological, biological and prognostic features into three subgroups according to the immunohistochemichal expression, which is similar to the genetic expression of the tumor. These groups, known as luminal, HER2 enriched and triple negative, are classified according to the positivity or negativity of nuclear receptors (estrogen [ER] and progesterone receptors [PR]) or membrane receptors (HER2). Triple negative tumors do not express positivity for any of these receptors
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