Relevant bibliographies by topics / Perkin reaction and Pechmann reaction

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  1. Journal articles
  2. Dissertations / Theses
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Academic literature on the topic 'Perkin reaction and Pechmann reaction'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Perkin reaction and Pechmann reaction"

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G.Nagaraju1, *. Dr.Vijaya Kuchana. "A REVIEW ON BIOLOGICAL ACTIVITY AND SYNTHETIS OF COUMARINS." Indo American Journal of Pharmaceutical Sciences 04, no. 10 (2017): 3510–27. https://doi.org/10.5281/zenodo.1004361.

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Coumarin (1,2-Benzopyrone or 2H-1-benzopyran-2-one, or phenylpropanoids, 1) and its derivatives (coumarins) are widely distributed throughout nature and many exhibit useful and diverse biological activities1,2. Coumarins occur as secondary metabolites in the seeds, roots and leaves of many plant species, notably in high concentration in the tonka bean and thus the name comes from a French word, coumarou, for the tonka bean. Their function is far from clear, although suggestions include plant growth regulations, fungistasis, bacteriostasis and, even, waste products3 . Some naturally occurring c
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Jumal, Juliana, and Norhanis Sakinah. "Synthesis, Characterization, and Applications of Coumarin Derivatives: A Short Review." Malaysian Journal of Science Health & Technology 7, no. 1 (2021): 62–68. http://dx.doi.org/10.33102/mjosht.v7i1.145.

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Coumarin and its derivatives represent one of the most active curriculums of compound possessing a broad spectrum of biological activity along with other applications such as insecticide and fragrance. There are various methodologies developed for the synthesis of coumarins. Classical routes to coumarins include Pechmann condensation, Knoevenagel condensation, Perkin reaction, and Wittig condensation reactions. Researchers have carried out adjustments and improvements to increase the efficacy and overcome the limitations from the classical route. In this review outline, coumarin derivatives we
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Nagaretnam, Prahadeesh, and Sithambaresan Maheswaran. "Synthesis of Simple Coumarins: Mixed Solvent Recrystallization Approach and Modification." RESEARCH REVIEW International Journal of Multidisciplinary 4, no. 1 (2019): 455–61. https://doi.org/10.5281/zenodo.2548800.

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Coumarin compounds have great interest for their wide range of medicinal and pharmacological properties as well as for their fluorescent properties. Simple coumarins are being the major precursor for the synthesis of most of the coumarin derivatives. Simple coumarin (C1) was synthesized by using Perkin condensation reaction whereas 7-hydroxy coumarin (C2) and 7-hydroxy-4-methyl coumarin (C3) were synthesized by using Pechmann condensation reaction. Solvent combination which gives higher recovery percentage on recrystallization was found out. The synthesized simple coumarins were characterized
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Gouda, Moustafa A., Mohammed A. Salem, and Mohamed H. Helal. "A Review on Synthesis and Pharmacological Activity of Coumarins and Their Analogs." Current Bioactive Compounds 16, no. 6 (2020): 818–36. http://dx.doi.org/10.2174/1573407215666190405154406.

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Background: Coumarins were reported to possess antimicrobial, antiinflammatory, antiplasmodial, antimalarial, and enzyme inhibitory properties. Furthermore, coumarins are a type of vitamin K antagonists. Coumarins had been first organized through perkin reaction; besides Knoevenagel condensation was mentioned as a critical synthetic approach for the synthesis of 3-substituted coumarins. Moreover, Pechmann, Reformatasky and Witting reactions were stated for the preparation of coumarins. Methods: We undertook a structured search of the method of preparation, the chemical reactivity and biologica
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Molnar, Maja, Melita Lončarić, and Marija Kovač. "Green Chemistry Approaches to the Synthesis of Coumarin Derivatives." Current Organic Chemistry 24, no. 1 (2020): 4–43. http://dx.doi.org/10.2174/1385272824666200120144305.

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This review is a compilation of the green synthetic methods used in the synthesis of coumarin derivatives. Coumarins are a class of compounds with a pronounced wide range of biological activities, which have found their application in medicine, pharmacology, cosmetics and food industry. Their biological activity and potential application are highly dependent on their structure. Therefore, many researchers have been performing the synthesis of coumarin derivatives on a daily basis. High demands for their synthesis often result in an increased generation of different waste chemicals. In order to
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Holden, Michael S., and R. David Crouch. "The Pechmann Reaction." Journal of Chemical Education 75, no. 12 (1998): 1631. http://dx.doi.org/10.1021/ed075p1631.

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Francisco, Carla S., Cristina S. Francisco, André F. Constantino, Álvaro Cunha Neto, and Valdemar Lacerda. "Synthetic Methods Applied in the Preparation of Coumarin-based Compounds." Current Organic Chemistry 23, no. 24 (2020): 2722–50. http://dx.doi.org/10.2174/1385272823666191121150047.

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Coumarins (2H-chromen-2-ones) are heterocyclic compounds of wide scientific interest due to their important biological and pharmaceutical properties such as antitumor, antioxidant, anti-inflammatory and antimicrobial activities as well as enzymatic inhibitors related to neurodegenerative diseases. Due to their structural variability, this compound class has been attracting considerable interest in the natural products and synthetic organic chemistry areas. Coumarins and their derivatives have been prepared by a variety of methods, including Perkin, Wittig and Reformatsky reactions, Pechmann an
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Gurumeet, C. Wadhawa 1. *. Harshada Deshmukh 2. Vitthal S. Shivankar 3. Yashwant A. Gaikwad 4. "ONE-POT SYNTHESIS OF THE COUMARINE UNDER GREEN APPROACH USING FERROUS SULPHATE AS CATALYST." Journal of Pharma Research 8, no. 4 (2019): 132–35. https://doi.org/10.5281/zenodo.2647854.

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<strong><em>ABSTRACT</em></strong> <strong><em>S</em></strong><em>ynthesis of various substituted Coumarins from substituted phenol and &beta;-ketoester (Ethyl Acetoacetate) via Pechmann condensation using heterogeneous catalyst like red mud solvent free condition under sonication. Reaction required low reaction time, very mild reaction condition, at room temperature and easy workup with good yield of the product.</em> <strong><em>KEYWORDS:</em></strong><em> Coumarins, Pechmann condensation, Solvent free reaction, Sonication.</em>
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Khandekar, Amit C., and Bhushan M. Khadilkar. "Pechmann Reaction in Chloroaluminate Ionic Liquid." Synlett 2002, no. 01 (2002): 0152–54. http://dx.doi.org/10.1055/s-2002-19332.

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Stoyanov, E., and J. Mezger. "Pechmann Reaction Promoted by Boron Trifluoride Dihydrate." Molecules 10, no. 7 (2005): 762–66. http://dx.doi.org/10.3390/10070762.

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Dissertations / Theses on the topic "Perkin reaction and Pechmann reaction"

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Sarkar, Parantap. "The ceramidonine and perkin approaches to aromatic nanoribbons." Thesis, Bordeaux 1, 2012. http://www.theses.fr/2012BOR14555/document.

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Les nanorubans de graphène (NRGs) sont des matériaux prometteurs pour l'organique électronique, à mi chemin entre polymères conjugués et nanotubes de carbone. Deux approches différentes pour la synthèse de nanorubans aromatiques sont développées et évaluées. La première est fondée sur la formation de céramidonines par cyclisation d'arylamino-anthraquinones en milieu acide. Plusieurs tétraaza-arènes incorporant deux de ces unités sont obtenus, mais l'approche s'est uniquement avérée appropriée dans le cas de courts substrats. La seconde approche repose sur la condensation d'acides aryle-acétiqu
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Robert, Antoine. "Synthèse organique de macrocycles conjugués par réaction de Perkin." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0935/document.

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La synthèse organique contrôlée de nanobagues de carbone est un challenge scientifique de longue date. Ces composés polycycliques aromatiques cylindriques peuvent être définis comme des sections de nanotubes de carbone plus larges qu’épaisses ; et la courbure de leur système pi pourrait leur conférer des propriétés électroniques intéressantes.Depuis quelques années, notre équipe développe une approche générale de synthèse de composés aromatiques polycycliques fonctionnalisés par des fonctions carboxyliques. Cette approche repose sur la réaction de Perkin entre des acides aryle-acétiques et des
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Naulet, Guillaume. "Techniques de protection pour la synthèse de larges arènes polycycliques par réaction de Perkin." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0188/document.

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La variante « glyoxylique » de la réaction de Perkin permet de lier entre eux deux fragments aromatiques par un pont maléique. La rigidification de cet intermédiaire flexible mène à des systèmes aromatiques polycycliques étendus par création des liaisons carbone-carbone manquantes. Cette stratégie requiert l'utilisation d'acides arylacétiques et arylglyoxyliques, et l’utilisation d'unités bifonctionnelles a auparavant permis la synthèse de cibles variées allant des phénacènes plans aux (poly)hélicènes très distordus, mais aussi des macrocycles conjugués. Afin d'étendre la taille et la variété
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Karri, Phaneendrasai. "Mechanistic And Synthetic Investigations On Carboxylic Anhydrides And Their Analogs." Thesis, 2008. https://etd.iisc.ac.in/handle/2005/1058.

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This thesis reports diverse synthetic and mechanistic studies in six chapters, as summarized below. Chapter 1. Revised mechanism and improved methodology for the perkin condensation.1 The generally accepted mechanism for the well-known Perkin condensation is unviable for at least two reasons: (1) the normally employed base, acetate ion, is too weak to deprotonate acetic anhydride (Ac2O, the substrate); and (2) even were Ac2O to be derprotonated , its anion would rapidly fragment to ketene and acetate ion at the high temperatures employed for the reaction. It has proved in this study that the
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Karri, Phaneendrasai. "Mechanistic And Synthetic Investigations On Carboxylic Anhydrides And Their Analogs." Thesis, 2008. http://hdl.handle.net/2005/1058.

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This thesis reports diverse synthetic and mechanistic studies in six chapters, as summarized below. Chapter 1. Revised mechanism and improved methodology for the perkin condensation.1 The generally accepted mechanism for the well-known Perkin condensation is unviable for at least two reasons: (1) the normally employed base, acetate ion, is too weak to deprotonate acetic anhydride (Ac2O, the substrate); and (2) even were Ac2O to be derprotonated , its anion would rapidly fragment to ketene and acetate ion at the high temperatures employed for the reaction. It has proved in this study that the P
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Book chapters on the topic "Perkin reaction and Pechmann reaction"

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Li, Jie Jack. "Perkin reaction." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_209.

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Li, Jie Jack. "Perkin reaction." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_196.

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Li, Jie Jack. "Perkin reaction (cinnamic acid synthesis)." In Name Reactions. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_228.

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Li, Jie Jack. "Perkin reaction (cinnamic acid synthesis)." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_217.

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Vanderwal, C. D., and E. N. Jacobsen. "Perkin Reaction." In Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts. Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-020-00546.

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"The Perkin Reaction." In Laboratory Experiments Using Microwave Heating. CRC Press, 2013. http://dx.doi.org/10.1201/b14645-8.

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Rosen, Terry. "The Perkin Reaction." In Comprehensive Organic Synthesis. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-08-052349-1.00034-2.

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Alonso, D. A., and C. Nájera. "The Perkin Reaction." In Monocyclic Arenes, Quasiarenes, and Annulenes. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-045-00163.

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Heravi, Majid M., Soheila Khaghaninejad, and Manizhe Mostofi. "Pechmann Reaction in the Synthesis of Coumarin Derivatives." In Advances in Heterocyclic Chemistry. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-800171-4.00001-9.

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Williams, A. C., and N. Camp. "Acid-Catalyzed Condensation of Phenols and 1,3-Dicarbonyl Compounds (The Pechmann Reaction)." In Six-Membered Hetarenes with One Chalcogen. Georg Thieme Verlag KG, 2003. http://dx.doi.org/10.1055/sos-sd-014-00324.

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Conference papers on the topic "Perkin reaction and Pechmann reaction"

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Majumder, Suman, та P. L. Majumder. "Further Evidence for the Mechanism of Formation ofCoumarin by Perkin Reaction from salicylaldehyde and a Novel Synthesis of 1,1-diphenyl-2(2'-hydroxyphenyl) ethene from O-α,α-diphenylacetylsalicylaldehyde with Et3N". У The 11th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2007. http://dx.doi.org/10.3390/ecsoc-11-01310.

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