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Journal articles on the topic 'Persistent pulmonary hypertension of the newborn'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

Šebková, S., V. Tomek, P. Zemanová, and Jan Janota. "Heart Failure Treated with Low-dose Milrinone in a Full-term Newborn." Prague Medical Report 113, no. 1 (2012): 58–65. http://dx.doi.org/10.14712/23362936.2015.38.

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A term newborn with a hypocontractile myocardium complicating persistent pulmonary hypertension of the newborn was successfully treated with a low-dose phosphodiesterase III inhibitor milrinone. Echocardiography diagnosed heart failure with a left ventricular ejection fraction of 35% and a left ventricular shortening fraction of 18% and severe persistent pulmonary hypertension of the newborn with oxygenation index of 28. Milrinone was started at an initial dose of 50 mcg/kg, followed by continuous infusion of 0.20 mcg/kg/min. With lowdose milrinone oxygenation index decreased to 3 within 6 hours, left ventricular ejection fraction and left ventricular shortening fraction increased to 57%, and 30%, respectively. Low doses of milrinone might be promising in the treatment of heart failure and persistent pulmonary hypertension of the newborn in term newborns.

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2

Lister, George. "Persistent Pulmonary Hypertension of the Newborn." International Journal of Technology Assessment in Health Care 7, S1 (January 1991): 66–69. http://dx.doi.org/10.1017/s0266462300012538.

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Persistent pulmonary hypertension of the newborn or persistent fetal circulation is a clinical syndrome that is usually apparent within the first 2 days after birth because of the presence of hypoxemia (2;12;19). The syndrome was first described in an abstract by Gersony, Due, and Sinclair (6) in 1969. Two infants were reported who had “RV decompensation, cyanosis and clear lung fields… in the absence of recognizable cardiac, pulmonary, hematologic or CNS disease.” The syndrome has been associated with aspiration of meconium, diaphragmatic hernia, asphyxia, hemorrhage, shock, and maternal infection (4;18). In other cases, there is no clear antecedent event. Despite considerable interest in the problem and a wealth of research related to pulmonary vasoregulation and vascular development in the fetus and newborn, the etiology of the syndrome remains obscure 20 years since its recognition.

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3

Hussain, Manzoor. "Persistent Pulmonary Hypertension of Newborn (PPHN)." Dhaka Shishu (Children) Hospital Journal 35, no. 2 (October 12, 2020): 90–93. http://dx.doi.org/10.3329/dshj.v35i2.49687.

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4

Mathew, Bobby, and Satyan Lakshminrusimha. "Persistent Pulmonary Hypertension in the Newborn." Children 4, no. 8 (July 28, 2017): 63. http://dx.doi.org/10.3390/children4080063.

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5

Thérèse, Perreault. "Persistent pulmonary hypertension of the newborn." Paediatric Respiratory Reviews 7 (January 2006): S175—S176. http://dx.doi.org/10.1016/j.prrv.2006.04.211.

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6

Walsh, Michele C., and Eileen K. Stork. "PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN." Clinics in Perinatology 28, no. 3 (September 2001): 609–27. http://dx.doi.org/10.1016/s0095-5108(05)70109-3.

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7

Walsh-Sukys, Michele C. "Persistent Pulmonary Hypertension of the Newborn." Clinics in Perinatology 20, no. 1 (March 1993): 127–43. http://dx.doi.org/10.1016/s0095-5108(18)30415-9.

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8

Hammerman, Cathy, David Yousefzadeh, Jung-Hwan Choi, and Kim-chi Bui. "Persistent Pulmonary Hypertension of the Newborn." Clinics in Perinatology 16, no. 1 (March 1989): 137–56. http://dx.doi.org/10.1016/s0095-5108(18)30660-2.

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9

Ostrea, Enrique M., Esterlita T. Villanueva-Uy, Girija Natarajan, and Herbert G. Uy. "Persistent Pulmonary Hypertension of the Newborn." Pediatric Drugs 8, no. 3 (2006): 179–88. http://dx.doi.org/10.2165/00148581-200608030-00004.

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10

Lakshminrusimha, S., and M. Keszler. "Persistent Pulmonary Hypertension of the Newborn." NeoReviews 16, no. 12 (December 1, 2015): e680-e692. http://dx.doi.org/10.1542/neo.16-12-e680.

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11

Vosatka, Robert J. "Persistent Pulmonary Hypertension of the Newborn." New England Journal of Medicine 346, no. 11 (March 14, 2002): 864. http://dx.doi.org/10.1056/nejm200203143461117.

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12

Verklan, M. Terese. "Persistent Pulmonary Hypertension of the Newborn." Journal of Perinatal & Neonatal Nursing 20, no. 1 (January 2006): 108–12. http://dx.doi.org/10.1097/00005237-200601000-00031.

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13

Niccolls, Christine. "Persistent pulmonary hypertension of the newborn." Journal of Neonatal Nursing 18, no. 2 (April 2012): 63–71. http://dx.doi.org/10.1016/j.jnn.2010.10.001.

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14

Fuloria, Mamta, and Judy L. Aschner. "Persistent pulmonary hypertension of the newborn." Seminars in Fetal and Neonatal Medicine 22, no. 4 (August 2017): 220–26. http://dx.doi.org/10.1016/j.siny.2017.03.004.

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15

Pierce, CM. "Persistent pulmonary hypertension of the newborn." Hospital Medicine 65, no. 7 (July 2004): 418–21. http://dx.doi.org/10.12968/hosp.2004.65.7.15474.

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16

Morin, F. C., and K. R. Stenmark. "Persistent pulmonary hypertension of the newborn." American Journal of Respiratory and Critical Care Medicine 151, no. 6 (June 1995): 2010–32. http://dx.doi.org/10.1164/ajrccm.151.6.7767553.

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17

BURNARD, E. D. "Persistent pulmonary hypertension in the newborn." Journal of Paediatrics and Child Health 25, no. 2 (April 1989): 59–60. http://dx.doi.org/10.1111/j.1440-1754.1989.tb01416.x.

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18

Yu, Victor Y. H. "Persistent pulmonary hypertension in the newborn." Early Human Development 33, no. 3 (July 1993): 163–75. http://dx.doi.org/10.1016/0378-3782(93)90142-h.

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19

Teng, Ru-Jeng, and Tzong-Jin Wu. "Persistent pulmonary hypertension of the newborn." Journal of the Formosan Medical Association 112, no. 4 (April 2013): 177–84. http://dx.doi.org/10.1016/j.jfma.2012.11.007.

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20

Tiefenbrunn, Larry J., and Thomas A. Riemenschneider. "Persistent pulmonary hypertension of the newborn." American Heart Journal 111, no. 3 (March 1986): 564–72. http://dx.doi.org/10.1016/0002-8703(86)90065-7.

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21

Chawla, Deepak. "Vasopressin in Persistent Pulmonary Hypertension of Newborn." Indian Journal of Pediatrics 88, no. 5 (March 26, 2021): 431–32. http://dx.doi.org/10.1007/s12098-021-03732-6.

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22

Ehlen, Michael, and Beatrix Wiebe. "Iloprost in persistent pulmonary hypertension of the newborn." Cardiology in the Young 13, no. 4 (August 2003): 361–63. http://dx.doi.org/10.1017/s1047951103000726.

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Aerosolized iloprost is now used as a therapeutic option in the treatment of pulmonary hypertension. We report on the administration of this derivative of prostacycline in treating severe pulmonary hypertension of the newborn. The combination of iloprost instilled endotracheally and inhaled was chosen as a last attempt at treatment in a critically ill patient who did not respond to advanced conventional treatments, including high frequency oscillation and inhalation of nitric oxide. The use of iloprost converted permanently the right-to-left shunting, leading to a substantial improvement in oxygenation.

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23

Suguihara, Cleide. "Treatment of persistent pulmonary hypertension of the newborn." Jornal de Pediatria 77, no. 7 (July 15, 2001): 17–24. http://dx.doi.org/10.2223/jped.215.

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24

Latini, Giuseppe, Antonio Del Vecchio, Claudio De Felice, Alberto Verrotti, and Eduardo Bossone. "Persistent Pulmonary Hypertension of the Newborn: Therapeutical Approach." Mini-Reviews in Medicinal Chemistry 8, no. 14 (December 1, 2008): 1507–13. http://dx.doi.org/10.2174/138955708786786507.

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25

Field, D. "Management of persistent pulmonary hypertension of the newborn." Current Paediatrics 7, no. 2 (June 1997): 73–77. http://dx.doi.org/10.1016/s0957-5839(97)80184-4.

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26

Sharma, Mukti, Karthik Ram Mohan, Shankar Narayan, and Lokesh Chauhan. "Persistent pulmonary hypertension of the newborn: a review." Medical Journal Armed Forces India 67, no. 4 (October 2011): 348–53. http://dx.doi.org/10.1016/s0377-1237(11)60082-8.

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27

&NA;. "Management of persistent pulmonary hypertension of the newborn." Inpharma Weekly &NA;, no. 777 (March 1991): 20. http://dx.doi.org/10.2165/00128413-199107770-00057.

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28

SEPKOWITZ, SAMUEL. "Mortality of Persistent Pulmonary Hypertension of the Newborn." Archives of Pediatrics & Adolescent Medicine 139, no. 2 (February 1, 1985): 115. http://dx.doi.org/10.1001/archpedi.1985.02140040013012.

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29

Koren, G., and H. Nordeng. "SSRIs and persistent pulmonary hypertension of the newborn." BMJ 344, jan12 3 (January 12, 2011): d7642. http://dx.doi.org/10.1136/bmj.d7642.

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30

Oishi, Peter E., and Roberta L. Keller. "When persistent pulmonary hypertension of the newborn persists*." Pediatric Critical Care Medicine 13, no. 2 (March 2012): 224–25. http://dx.doi.org/10.1097/pcc.0b013e3182266a6c.

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31

Lauterbach, R. "Pentoxifylline treatment of persistent pulmonary hypertension of newborn." European Journal of Pediatrics 152, no. 5 (May 1993): 460. http://dx.doi.org/10.1007/bf01955916.

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32

Rong, Qunfang. "Tolazoline treating persistent pulmonary hypertension of the newborn." Early Human Development 84 (November 2008): S96. http://dx.doi.org/10.1016/j.earlhumdev.2008.09.247.

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33

Konduri, G. Ganesh. "New approaches for persistent pulmonary hypertension of newborn." Clinics in Perinatology 31, no. 3 (September 2004): 591–611. http://dx.doi.org/10.1016/j.clp.2004.04.001.

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34

Guzoglu, Nilufer, Fatma Nur Sari, and Nahide Altug. "An unusual cause of refractory persistent pulmonary hypertension of the newborn: anomalous origin of one pulmonary artery." Cardiology in the Young 24, no. 3 (July 18, 2013): 543–45. http://dx.doi.org/10.1017/s1047951113000826.

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AbstractPersistent pulmonary hypertension of the newborn is a source of considerable mortality and morbidity. Anomalous origin of one pulmonary artery, an uncommon congenital cardiac malformation, is a rare cause of persistent pulmonary hypertension. Here, we report the case of a patient with an anomalous origin of one pulmonary artery from the innominate artery who presented with persistent pulmonary hypertension refractory to treatment.

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35

Demir, Nihat, Erdal Peker, İbrahim Ece, Sultan Kaba, Kemal Ağengin, and Oğuz Tuncer. "A Rare Cause of Persistent Pulmonary Hypertension Resistant to Therapy in The Newborn: Short-Rib Polydactyly Syndrome." Case Reports in Pulmonology 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/274639.

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Short-rib polydactyly syndrome is an autosomal recessively inherited lethal skeletal dysplasia. The syndrome is characterized by marked narrow fetal thorax, short extremities, micromelia, cleft palate/lip, polydactyly, cardiac and renal abnormalities, and genital malformations. In cases with pulmonary hypoplasia, persistent pulmonary hypertension of the newborn can develop. In this paper, we present a term newborn with persistent pulmonary hypertension of the newborn, which has developed secondary to short-rib polydactyly syndrome and was resistant to therapy with inhaled nitric oxide and oral sildenafil.

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36

Roofthooft, M. T. R., A. Elema, K. A. Bergman, and R. M. F. Berger. "Patient Characteristics in Persistent Pulmonary Hypertension of the Newborn." Pulmonary Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/858154.

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Objective. To assess the impact of PPHN on mortality, morbidity, and behavioural skills.Methods. A retrospective observational study of 143 newborns with PPHN, over an 11-year period, using objective health-status data from medical records and family doctors, and subjective health status data from a standardized Child Behaviour Checklist.Results. The majority of patients were males, treated with inhaled nitric oxide had maladaptation/maldevelopment as pathophysiological mechanism and a gestational age >37 weeks. In term newborns, types of pathophysiological mechanism () and Oxygen Index () were independent predicting risk factors for PPHN-related mortality. Analysis of preexisting disease and outcome categories in term newborns showed only a significant correlation between the use of iNO and respiratory complaints (), not confirmed by multivariate analysis and regression analysis.Conclusions. PPHN is a serious, often fatal condition. The incidence of PPHN in preterm newborns is high. In term survivors, PPHN had no additional role in morbidity/outcome.

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37

Zapol, Warren M. "Nitric Oxide Story." Anesthesiology 130, no. 3 (March 1, 2019): 435–40. http://dx.doi.org/10.1097/aln.0000000000002579.

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Abstract Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn. By Roberts JD, Polaner DM, Lang P, and Zapol WM. Lancet 1992; 130:435–40. Reprinted with permission. NO has vasodilatory effects on the pulmonary vasculature in adults and animals. We examined the effects on systemic oxygenation and blood pressure of inhaling up to 80 parts per million by volume of NO at fraction of inspired oxygen 0.9 for up to 30 min by six infants with persistent pulmonary hypertension of the newborn. In all infants, this treatment rapidly and significantly increased preductal oxygen saturation; in five infants, postductal oxygen saturation and oxygen tensions also increased. Inhalation of NO did not cause systemic hypotension or raise methemoglobin. These data suggest that low levels of inhaled NO have an important role in the reversal of hypoxemia due to persistent pulmonary hypertension of the newborn.

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38

Delaney, Cassidy, and David N. Cornfield. "Risk Factors for Persistent Pulmonary Hypertension of the Newborn." Pulmonary Circulation 2, no. 1 (January 2012): 15–20. http://dx.doi.org/10.4103/2045-8932.94818.

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39

Esther Jurfest Ceccon, Maria, and Werther Brunow de Carvalho. "Ventilatory Support in Persistent Pulmonary Hypertension of the Newborn." Current Respiratory Medicine Reviews 8, no. 1 (February 1, 2012): 28–36. http://dx.doi.org/10.2174/157339812798868834.

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40

Son, Su Bin, Kyung Ah Kim, So Young Yun, Sun Young Ko, Yeon Kyung Lee, and Son Moon Shin. "Oral Sildenafil in Persistent Pulmonary Hypertension of the Newborn." Journal of the Korean Society of Neonatology 18, no. 1 (2011): 124. http://dx.doi.org/10.5385/jksn.2011.18.1.124.

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41

Qasim, Amna, and Sunil K. Jain. "Milrinone Use in Persistent Pulmonary Hypertension of the Newborn." NeoReviews 21, no. 3 (March 2020): e165-e178. http://dx.doi.org/10.1542/neo.21-3-e165.

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42

Spitzer, Alan R., Jonathan Davis, William T. Clarke, Judy Bernhaum, and William W. Fox. "Pulmonary Hypertension and Persistent Fetal Circulation in the Newborn." Clinics in Perinatology 15, no. 2 (June 1988): 389–413. http://dx.doi.org/10.1016/s0095-5108(18)30718-8.

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43

Weinberger, B. "Pharmacologic therapy of persistent pulmonary hypertension of the newborn." Pharmacology & Therapeutics 89, no. 1 (January 2001): 67–79. http://dx.doi.org/10.1016/s0163-7258(00)00104-2.

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44

Haworth, Sheila G. "The pathophysiology of persistent pulmonary hypertension of the newborn." Seminars in Neonatology 2, no. 1 (February 1997): 13–23. http://dx.doi.org/10.1016/s1084-2756(97)80021-8.

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45

Macrae, Duncan J. "Drug therapy in persistent pulmonary hypertension of the newborn." Seminars in Neonatology 2, no. 1 (February 1997): 49–58. http://dx.doi.org/10.1016/s1084-2756(97)80024-3.

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46

Field, David J. "Clinical management of persistent pulmonary hypertension of the newborn." Seminars in Neonatology 2, no. 1 (February 1997): 59–68. http://dx.doi.org/10.1016/s1084-2756(97)80025-5.

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47

Macrae, Duncan J. "Drug therapy in persistent pulmonary hypertension of the newborn." Seminars in Neonatology 3, no. 1 (February 1998): 73. http://dx.doi.org/10.1016/s1084-2756(98)80151-6.

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48

Abman, Steven H. "Persistent Pulmonary Hypertension of the Newborn: Pathophysiology and Treatment." Advances in Pulmonary Hypertension 5, no. 2 (April 1, 2006): 22–30. http://dx.doi.org/10.21693/1933-088x-5.2.22.

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49

Greenough, Anne. "Therapeutic strategies in persistent pulmonary hypertension of the newborn." Progress in Pediatric Cardiology 9, no. 2 (March 1998): 69–72. http://dx.doi.org/10.1016/s1058-9813(98)00046-0.

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50

Van Marter, Linda J., Alan Leviton, Marcello Pagano, and Elizabeth N. Allred. "EPIDEMIOLOGIC ANTECEDENTS OF PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN." Pediatric Research 32, no. 5 (November 1992): 635. http://dx.doi.org/10.1203/00006450-199211000-00185.

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