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Journal articles on the topic 'Person Level Model of Pharmaceutical Benefits'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Soller, Jeffrey A. "The potential implications of person-to-person transmission of viral infection for US EPA's Groundwater Rule." Journal of Water and Health 7, no. 2 (2009): 208–23. http://dx.doi.org/10.2166/wh.2009.118.

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The risk characterization method employed by US EPA to quantitatively characterize the benefits of the Groundwater Rule (GWR) for drinking water computes person-to-person transmission intensity as the product of the number of primary illnesses and a static secondary morbidity factor. A population level infectious disease health effects model is used here to evaluate the implications of secondary transmission on exposures to viruses that are relevant to the GWR. These implications are evaluated via a hypothetical case study in which it is assumed that a tour group from a large population centre

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Hornke, Lutz F. "Benefits from Computerized Adaptive Testing as Seen in Simulation Studies." European Journal of Psychological Assessment 15, no. 2 (1999): 91–98. http://dx.doi.org/10.1027//1015-5759.15.2.91.

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Summary: Item parameters for several hundreds of items were estimated based on empirical data from several thousands of subjects. The logistic one-parameter (1PL) and two-parameter (2PL) model estimates were evaluated. However, model fit showed that only a subset of items complied sufficiently, so that the remaining ones were assembled in well-fitting item banks. In several simulation studies 5000 simulated responses were generated in accordance with a computerized adaptive test procedure along with person parameters. A general reliability of .80 or a standard error of measurement of .44 was u

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Walker, Agnes. "Distributional impact of higher patient contributions to Australia's Pharmaceutical Benefits Scheme." Australian Health Review 23, no. 2 (2000): 32. http://dx.doi.org/10.1071/ah000032.

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This paper uses NATSEM's Pharmaceutical Benefits Model to analyse the effects of a hypothetical25 per cent rise in patient contributions to prescribed medicines under Australia's PharmaceuticalBenefits Scheme (PBS). The model, based on microsimulation techniques, is able to provide a muchbroader range of outcomes information, at a much greater level of detail, than is possible withtraditional methods.Higher patient contributions are analysed in terms of their impact on the government to patient splitin PBS costs, as well as the distribution of such costs across age groups, family incomes, fami

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Mudimu, Edinah, Kathryn Peebles, Zindoga Mukandavire, et al. "Individual and community-level benefits of PrEP in western Kenya and South Africa: Implications for population prioritization of PrEP provision." PLOS ONE 15, no. 12 (2020): e0244761. http://dx.doi.org/10.1371/journal.pone.0244761.

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Background Pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV and has the potential to significantly impact the HIV epidemic. Given limited resources for HIV prevention, identifying PrEP provision strategies that maximize impact is critical. Methods We used a stochastic individual-based network model to evaluate the direct (infections prevented among PrEP users) and indirect (infections prevented among non-PrEP users as a result of PrEP) benefits of PrEP, the person-years of PrEP required to prevent one HIV infection, and the community-level impact of providing PrEP to popul

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Dong, Xiaojing, Puneet Manchanda, and Pradeep K. Chintagunta. "Quantifying the Benefits of Individual-Level Targeting in the Presence of Firm Strategic Behavior." Journal of Marketing Research 46, no. 2 (2009): 207–21. http://dx.doi.org/10.1509/jmkr.46.2.207.

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The authors develop a method to quantify the benefits of individual-level targeting when the data reflect firm strategic behavior—that is, when firms (1) are engaged in targeting and (2) take into account the actions of competing firms. This article studies a pharmaceutical firm's decision on the allocation of detailing visits across individual physicians. For this analysis, the authors develop, at the individual level, a model of prescriptions and a model of detailing. Using physician panel data, they estimate, at the physician level, the parameters of the prescription and detailing models jo

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Yu, Wenguang, Bing Li, and Xianghan Zhu. "Income Redistribution Effect of Raising the Overall Planning Level of Basic Endowment Insurance for Urban Employees in China." Sustainability 13, no. 2 (2021): 709. http://dx.doi.org/10.3390/su13020709.

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It is the focus of social security system reform at this stage in China to promote the transition of basic endowment insurance for urban employees from provincial overall planning level to national overall planning level, which is of great significance to the realization of fair and efficient of economic development. Based on the micro data of China Household Finance Survey 2017 (CHFS2017), this paper first establishes a personal wage prediction model to estimate the distribution of personal lifetime wage income, then designs two pension collection and payment plans of “direct national overall

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Bungard, Tammy J., Stephen L. Archer, Peter Hamilton, Bruce Ritchie, Wayne Tymchak, and Ross T. Tsuyuki. "Bringing the Benefits of Anticoagulation Management Services to the Community." Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 139, no. 2 (2006): 58–64. http://dx.doi.org/10.1177/171516350613900207.

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Background: While warfarin is efficacious for the prevention of thromboembolic disorders, many patients are undertreated. To optimize therapy, anticoagulation management services (AMSs) deliver a coordinated, focused approach to this care; however, AMSs are limited in their ability to impact patients outside of tertiary care settings. Objective: To describe the methods used to develop community-based AMSs across Alberta. Methods: Through a three-staged approach, this project created community-based, pharmacist-managed AMSs for patients requiring warfarin therapy. Stage I was the initiation of

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Liu, Wan-Yu, Bo-Sheng Fang, and Chi-Ming Hsieh. "Evaluating the Recreation Value of Alishan National Forest Recreation Area in Taiwan." Forests 12, no. 9 (2021): 1245. http://dx.doi.org/10.3390/f12091245.

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This study aimed to construct an effective model to estimate the recreation value and total annual recreation benefits of the Alishan National Forest Recreation Area (ANFR) through the travel cost method. Negative binomial regression was also employed to estimate the demand function. This study sorted participants based on gender, age, level of education, personal monthly income, occupation, and place of residence to examine their differences in perceived recreation value and recreation demand. The survey responses revealed that most tourists were mainly middle aged, and took family vacations.

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Marra, Carlo, Karissa Johnston, Valerie Santschi, and Ross T. Tsuyuki. "Cost-effectiveness of pharmacist care for managing hypertension in Canada." Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 150, no. 3 (2017): 184–97. http://dx.doi.org/10.1177/1715163517701109.

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Background: More than half of all heart disease and stroke are attributable to hypertension, which is associated with approximately 10% of direct medical costs globally. Clinical trial evidence has demonstrated that the benefits of pharmacist intervention, including education, consultation and/or prescribing, can help to reduce blood pressure; a recent Canadian trial found an 18.3 mmHg reduction in systolic blood pressure associated with pharmacist care and prescribing. The objective of this study was to evaluate the economic impact of such an intervention in a Canadian setting. Methods: A Mar

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Scobee, Shari P., Michael DuRoss, and Edward C. Ratledge. "Development of Trip Production Rates for Synthesized Households." Transportation Research Record: Journal of the Transportation Research Board 1625, no. 1 (1998): 79–85. http://dx.doi.org/10.3141/1625-10.

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Survey nonresponse bias is an important consideration in the development of survey designs for transportation studies. Researchers at the University of Delaware have developed a technique for reducing the survey nonresponse, as well as the cost of the travel survey. The method involves obtaining complete household and person characteristics for each household member; however, detailed travel data are gathered for only one randomly selected household member. Although the University of Delaware survey technique provides multiple benefits with respect to survey response rates and costs, it presen

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Santangelo, Philip S., Jana Holtmann, Georg Hosoya, et al. "Within- and Between-Persons Effects of Self-Esteem and Affective State as Antecedents and Consequences of Dysfunctional Behaviors in the Everyday Lives of Patients With Borderline Personality Disorder." Clinical Psychological Science 8, no. 3 (2020): 428–49. http://dx.doi.org/10.1177/2167702620901724.

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Dysfunctional behaviors are conceptualized as maladaptive affective coping attempts in borderline personality disorder (BPD). The recent benefits-and-barriers model extended the affective function assumption by adding self-esteem as a barrier to engaging in dysfunctional behaviors. Patients with BPD ( N = 119) carried e-diaries to report their current self-esteem, emotional valence, tense arousal, and whether they engaged in dysfunctional behaviors 12 times a day for 4 days. Dynamic structural equation modeling revealed that on the within-person level, high momentary negative affect predicted

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Mott, Adele, Susan Kafka, and Adam Sutherland. "ASSESSING PHARMACEUTICAL CARE NEEDS OF PAEDIATRIC IN-PATIENTS: A TEAM BASED APPROACH." Archives of Disease in Childhood 101, no. 9 (2016): e2.34-e2. http://dx.doi.org/10.1136/archdischild-2016-311535.4.

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AimsTo pilot a novel approach to providing pharmaceutical care to paediatric inpatients using structured referral and assessment tools. Using standardised referral criteria to ensure patients are assessed by appropriately skilled pharmacists.MethodThree wards of varying acuity and specialism were selected in a tertiary children's hospital in England - General Paediatric Ward (GPW), High Dependency Unit (HDU) and Haematology/Oncology Ward (HOW). The project ran for three months.Three levels of pharmacist were involved: Band 8 (“Level 3”), Paediatric Band 7 (“Level 2”) and rotational band 6/7 (“

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Haji, Haji Y., and Abdulah H. Al- Dabash. "Estimation Tourism Use Value of Galy Ali Begg Waterfall, Kurdistan Region, Iraqx`." Academic Journal of Nawroz University 9, no. 4 (2020): 81. http://dx.doi.org/10.25007/ajnu.v9n4a893.

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In this paper the tourism value of Gally Ali Begg waterfall has been estimated by using Individual Travel Cost Method (TCM). A questionnaire was used for the survey to obtain the tourist value of this touristic site. Multiple linear regression analysis model has been developed using individual travel cost method. The results of the study show that the tourism value of Gay Ali Begg waterfall (consumer surplus) per person per year as is (6259ID)( US$5.1)and the total consumer surplus for the study sample estimated as ( 9008353 ID )( US$7354) . One of the most significant findings that emerge fro

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Dogbe, Marina G., Ambinintsoa Yattussia Mafilaza, Carla Vânia Eleutério, Helena Cabral-Marques, Sandra Simões, and Maria Manuela Gaspar. "Pharmaceutical Benefits of Fluticasone Propionate Association to Delivery Systems: In Vitro and In Vivo Evaluation." Pharmaceutics 11, no. 10 (2019): 521. http://dx.doi.org/10.3390/pharmaceutics11100521.

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The objective of the present work was to characterize the ability of liposomes and cyclodextrin (CyD) complexes to modulate the in vivo profile of fluticasone (FTZ). In vitro cell compatibility tests were performed, exposing A549 cells to FTZ in the free form and FTZ associated to liposomes and complexed with CyD. The in vivo fate of a selected FTZ liposomal formulation and of several FTZ CyD complexes was achieved following intranasal instillation or pulmonary administration in BALB/c mice, respectively. For pulmonary administration, an inhalation chamber was constructed to enable the simulta

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Rains, Stephen A., and Andrew C. High. "The Effects of Person-Centered Social Support Messages on Recipient Distress Over Time within a Conversation." Journal of Communication 71, no. 3 (2021): 380–402. http://dx.doi.org/10.1093/joc/jqab010.

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Abstract Although prior research documents the benefits of supportive messages containing higher levels of verbal person centeredness (VPC), the effects of this message property over time within a discussion are not well understood. This project evaluated predictions about the effects of high and low VPC messages over time drawn from the theory of conversationally induced reappraisals and the dual-process model of supportive communication outcomes. Participants (N = 281) completed an interaction with a computerized support provider in which the level of VPC was manipulated. Before and after th

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Demir, Cengiz, Nazli A. Ayyildiz Unnu, and Emel Erturk. "DIAGNOSING THE ORGANIZATIONAL CULTURE OF A TURKISH PHARMACEUTICAL COMPANY BASED ON THE COMPETING VALUES FRAMEWORK / TURKIJOS FARMACIJOS KOMPANIJŲ ORGANIZACINĖS KULTŪROS VERTINIMAS, PAGRĮSTAS KONKURENCIJOS VERTINIMO SISTEMA." Journal of Business Economics and Management 12, no. 1 (2011): 197–217. http://dx.doi.org/10.3846/16111699.2011.555451.

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Organizational culture plays a significant role in understanding organizational dynamics and it distinguishes the members of one organization from other people. In this regard; it is found out that an organization, which is able to maintain a strong and “preferred” culture, is likely to enjoy many benefits such as higher levels of performance, person-organization fit, commitment, job satisfaction and competitive advantage. Thus, the purpose of this study is to diagnose the culture of a pharmaceutical company, which is located in Turkey, and find out the “perceived” and “preferred” cultural pro

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PETTEY, W. B. P., M. E. CARTER, D. J. A. TOTH, M. H. SAMORE, and A. V. GUNDLAPALLI. "Constructing Ebola transmission chains from West Africa and estimating model parameters using internet sources." Epidemiology and Infection 145, no. 10 (2017): 1993–2002. http://dx.doi.org/10.1017/s0950268817000760.

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SUMMARYDuring the recent Ebola crisis in West Africa, individual person-level details of disease onset, transmissions, and outcomes such as survival or death were reported in online news media. We set out to document disease transmission chains for Ebola, with the goal of generating a timely account that could be used for surveillance, mathematical modeling, and public health decision-making. By accessing public web pages only, such as locally produced newspapers and blogs, we created a transmission chain involving two Ebola clusters in West Africa that compared favorably with other published

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Wu, Changfan, Xiaotong Han, Xixi Yan, Xianwen Shang, Lei Zhang, and Mingguang He. "Associations between physical activity and cataract treated surgically in patients with diabetes: findings from the 45 and Up Study." British Journal of Ophthalmology 103, no. 8 (2018): 1099–105. http://dx.doi.org/10.1136/bjophthalmol-2018-312407.

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AimTo investigate the association between physical activity (PA) and incidence of cataract surgery among patients with diabetes.MethodsWe obtained data from all diabetic subjects aged 45-65 years from the baseline of the prospective 45 and Up Study from 2006 to 2009 and linked to the Medicare Benefits Schedule (MBS) and Pharmaceutical Benefits Scheme (PBS) until 2016. Diabetes was defined as self-reported on questionnaire or diabetes medication history based on PBS. Cataract surgery was determined based on the MBS, and metabolic equivalent intensity level number of PA sessions per week was use

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Lo, Jason C. K., Harry W. Pan та Jenny K. W. Lam. "Inhalable Protein Powder Prepared by Spray-Freeze-Drying Using Hydroxypropyl-β-Cyclodextrin as Excipient". Pharmaceutics 13, № 5 (2021): 615. http://dx.doi.org/10.3390/pharmaceutics13050615.

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The prospect of inhaled biologics has garnered particular interest given the benefits of the pulmonary route of administration. Pertinent considerations in producing inhalable dry powders containing biological medicines relate to aerosol performance and protein stability. Spray-freeze-drying (SFD) has emerged as an established method to generate microparticles that can potentially be deposited in the lungs. Here, the SFD conditions and formulation composition were evaluated using bovine serum albumin (BSA) as a model protein and 2-hydroxypropyl-beta-cyclodextrin (HPβCD) as the protein stabiliz

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Coşkun, Lokman. "The Reciprocal Effects of Both Responsibility and Motivation in Foreign Language Learning Process: a Comparative Study." European Journal of Language and Literature 4, no. 1 (2016): 138. http://dx.doi.org/10.26417/ejls.v4i1.p138-143.

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This study aims to analyze the significance of personal responsibility and its positive benefits and also its relations with motivation in foreign language learning environment. Particularly, responsibility enhances motivation and benefits from values and capabilities, since they are considered as central to what it means to learn in the life. In accordance with it, each individual has freedom how to consider his/her choices, behaviors, and actions in the life as well. The study on personal responsibilities and motivation were taken into account to demonstrate how these two features of foreign

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Barnes, A. Keith, Jack L. Mendleson, and Greg T. Horn. "Structured Mentorship For New Employees: A Case Study." Journal of Applied Business Research (JABR) 5, no. 1 (2011): 74. http://dx.doi.org/10.19030/jabr.v5i1.6379.

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In The Southland Corporations Pacific Western Division new field representatives are assigned a Sponsor/Mentor. Intentions include the provision of a neutral person with whom to talk-over problems. To examine the nature of sponsor/sponsoree relationships and to evaluate participant benefits a study was conducted involving structure interviews with sponsors and sponsorees. Grouped responses, in some of the focused areas of the research, provided indices (of satisfaction with the relationship, for example). In addition, sponsoree perceptions of their sponsors adherence to the six prescribed beha

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Kumar, Ramesh, Waqar Akbar, and Naveed R. Khan. "Moderating Role of Person Job-Fit Facet between Hierarchical Plateau and Turnover Intention." South Asian Journal of Management Sciences 15, no. 2 (2021): 176–90. http://dx.doi.org/10.21621/sajms.2021152.04.

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This study aims to examine the impact of hierarchical plateau on turnover intention with moderating role of person job-fit facet. Hierarchical plateau is a point of an individual's career life where the probability of being promoted further is low. The theory of work adjustment (TWA) is applied in this research study which measures that satisfaction level of an employee and leaving a company when needs and desired system of the person and the organization system mismatched at the workplace. Overall 260 employees participated by filling the self-administrated questionnaires from three different

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Rai, Alka, and Benjamin Nandy. "Employer brand to leverage employees’ intention to stay through sequential mediation model: evidence from Indian power sector." International Journal of Energy Sector Management 15, no. 3 (2021): 551–65. http://dx.doi.org/10.1108/ijesm-10-2019-0024.

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Purpose This study aims to explain the linkage between employer branding and employee retention; a sequential mediation is hypothesized, where it is proposed that the relationship between employer branding and employee retention is sequentially mediated by person–organization fit (P-O fit) and organizational identification. Design/methodology/approach The sample belongs to 224 executive-level employees of the Indian power sector organization. The sequential mediation model is tested by using SPSS macro command of Preacher and Hayes. Findings The findings established that the relationship betwe

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Olafenwa, Abiodun Taiwo, Ahmed Adeniyi Ojikutu, and Oladapo Alani Owoeye. "Managerial competencies and competitive advantage in pharmaceutical blockbusters." International Journal of Business, Management and Economics 2, no. 1 (2021): 53–79. http://dx.doi.org/10.47747/ijbme.v2i1.223.

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The study empirically tested the relationship between managerial competencies and competitive advantage in pharmaceutical blockbusters. According to the literature, blockbuster models and competitive strategies are significant determinants in organisational performance in the pharmaceutical industry context. However, the focus of this study is to determine whether efforts to combine managerial competence and the blockbuster model will reorient pharmaceutical companies to better competitive advantage by creating blockbuster drugs for the companies. This competitive advantage will position pharm

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Waldon, Mandy. "A rapid response and treatment service for care homes: a case study." British Journal of Community Nursing 26, no. 1 (2021): 6–12. http://dx.doi.org/10.12968/bjcn.2021.26.1.6.

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Rapid response services provide opportunities for older people living with frailty to remain in their own homes during an episode of deteriorating health. The government has announced additional funding to increase capacity and responsiveness for these services through the Ageing Well programme as part of the NHS Long Term Plan. Older people living with frailty are particularly at risk of the adverse effects of a hospital admission and evidence is emerging of the benefits of enhanced healthcare support to allow them to remain in their own home. The Hospital at Home model offers short-term, tar

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Fauquet-Alekhine, Philippe, Guillaume Bouhours, Justin Texier, Amaury Loret, Saadi Lahlou, and Jean-Claude Granry. "Training Improvement through Subjective Work Analysis: The Example of Radial Puncture." Global Journal of Health Science 13, no. 3 (2021): 59. http://dx.doi.org/10.5539/gjhs.v13n3p59.

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The aim was to test a method developed in nuclear industry applied to a simple activity, the radial artery puncture, and to assess its capacity to improve performance. The method involved digital ethnography based on the Square of PErceived ACtion model applied in real operating situation and first-person perspective video for post-analysis of the activity in order to improve training design. Two types of training sessions were compared in terms of trainees&rsquo; performance, one of them taking benefits of the digital ethnography analysis (restructured session) and the other without (clas

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Ramakrishnan, Ramya, Chongjie Zhang, and Julie Shah. "Perturbation Training for Human-Robot Teams." Journal of Artificial Intelligence Research 59 (July 31, 2017): 495–541. http://dx.doi.org/10.1613/jair.5390.

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In this work, we design and evaluate a computational learning model that enables a human-robot team to co-develop joint strategies for performing novel tasks that require coordination. The joint strategies are learned through "perturbation training," a human team-training strategy that requires team members to practice variations of a given task to help their team generalize to new variants of that task. We formally define the problem of human-robot perturbation training and develop and evaluate the first end-to-end framework for such training, which incorporates a multi-agent transfer learnin

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MacDonald, Shaunagh, Jane Clarbour, Clare Whitton, and Kelly Rayner. "The challenges of working with sexual offenders who have autism in secure services." Journal of Intellectual Disabilities and Offending Behaviour 8, no. 1 (2017): 41–54. http://dx.doi.org/10.1108/jidob-10-2016-0020.

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Purpose Previous literature has reported that working with sexual offenders can impact staff negatively (Hatcher and Noakes, 2010). In addition, working with individuals with intellectual disability also appears to be challenging. There are benefits stated of working with sexual offenders and the purpose of this paper is to seek to highlight the challenges and positive experiences of staff members working with sexual offenders who have autism. Design/methodology/approach As working with this population has not been previously investigated, a semi-structured interview was conducted to explore t

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Hasan, Hazriah, Ismail Ahmad, and Nur Aisyah Ghazali. "Comparative Analysis of Waqf Generosity Index (WGI) in Generation Y and Z." Research in World Economy 10, no. 2 (2019): 26. http://dx.doi.org/10.5430/rwe.v10n2p26.

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As the Islamic endowment (Waqf) has been practiced throughout the world, it is a challenge to measure the level of the generosity index on its practice. In fact, the awareness in performing Waqf among Muslims especially in the Generations Y and Z are important since it is valuable to the Muslims and concurrently can help those needy people. The study objective is to develop the generosity index among the two generations’ classifications. The variables that have been selected in this study namely trust, altruism, personal characteristics, self-image, religious value, psychological benefits, soc

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Lindsay Barr, Tremane, and John Reid. "Centralized decentralization for tribal business development." Journal of Enterprising Communities: People and Places in the Global Economy 8, no. 3 (2014): 217–32. http://dx.doi.org/10.1108/jec-10-2012-0054.

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Purpose – The purpose of this research was to identify and create a decentralized development system specific for the whanau (family) and hapu/runanga (sub-tribe) members of Te Rūnanga o Ngāi Tahu. In New Zealand, a number of Maori tribes have negotiated compensation with the New Zealand Government for past injustices. These assets are typically centralized within iwi (tribal) corporate structures to protect and grow the asset base on behalf of tribal constituents. This centralization of assets has caused political tension within tribes. Design/methodology/approach – This paper provides a case

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Mom, Tom J. M., Pepijn van Neerijnen, Patrick Reinmoeller, and Ernst Verwaal. "Relational Capital and Individual Exploration: Unravelling the Influence of Goal Alignment and Knowledge Acquisition." Organization Studies 36, no. 6 (2015): 809–29. http://dx.doi.org/10.1177/0170840615580009.

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We investigate how the relational capital of a person within an organization affects the extent to which she or he conducts exploration activities. Our theory separates out a negative effect that comes from aligning goals with other organizational members from a positive effect that stems from acquiring knowledge from them. Our data from 150 members of the R&D teams of three leading R&D-intensive firms support the theoretical model. By developing and testing this theory, we contribute to the literature on exploration, which lacks understanding of the antecedents of individual explorati

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Ziganshina, L. E., R. R. Niyazov, and A. U. Ziganshin. "The who concept of essential medicines and the who ethical criteria for medicinal drug promotion: history and lessons for domestic pharmaceutical sector." Kazan medical journal 94, no. 1 (2013): 95–100. http://dx.doi.org/10.17816/kmj1779.

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The review covers the history and evolution of the WHO initiatives in pharmaceutical policy - for better and safer use of medicines, their scientifically based selection and ethical promotion. The WHO Concept of Essential Medicines, the WHO vision of the Rational Use of medicines and the WHO Ethical Criteria for Medicinal Drug Promotion are reviewed. Contribution of these WHO designed initiatives, definitions and documents to Global Health, particularly relating to modern Russian health system problems is discussed. The principles and methodology of drug selection are presented. The review des

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Crudup, Terri, Linna Li, Jennifer Wright Dorr, et al. "Breast cancer survivorship and level of institutional involvement utilizing integrative oncology." Journal of Clinical Oncology 39, no. 15_suppl (2021): e18588-e18588. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18588.

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e18588 Background: A growing body of evidence has shown that a Whole Person Integrative Oncology approach, adding the use of complementary and lifestyle therapies to cancer treatments, benefits patients by improving patient-reported outcomes and potentially extending overall survival. This study aims to investigate the relationship between the survival outcomes of breast cancer patients and the level of involvement in Integrative Oncology at the institutions treating those patients. Methods: Between January 2013 and December 2014, 4,815 breast cancer patients were available for survival analys

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Angelis, Aris. "Evaluating the Benefits of New Drugs in Health Technology Assessment Using Multiple Criteria Decision Analysis: A Case Study on Metastatic Prostate Cancer With the Dental and Pharmaceuticals Benefits Agency (TLV) in Sweden." MDM Policy & Practice 3, no. 2 (2018): 238146831879621. http://dx.doi.org/10.1177/2381468318796218.

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Background. Multiple criteria decision analysis (MCDA) has been identified as a prospective methodology for assisting decision makers in evaluating the benefits of new medicines in health technology assessment (HTA); however, limited empirical evidence exists from real-world applications. Objective. To test in practice a recently developed MCDA methodological framework for HTA, the Advance Value Framework, in a proof-of-concept case study with decision makers. Methods. A multi-attribute value theory methodology was adopted applying the MACBETH questioning protocol through a facilitated decisio

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Moshtaghi Yazdani, Navid, and Reihaneh Kardehi Moghaddam. "Blood Glucose Regulation in Patients with Type 1 Diabetes by Robust Optimal Safety Critical Control." Frontiers in Health Informatics 10, no. 1 (2021): 80. http://dx.doi.org/10.30699/fhi.v10i1.286.

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Introduction: Diabetes disease is a group of metabolic diseases in which a person has high blood sugar, either because the pancreas does not produce enough insulin, or because cells do not respond to the insulin that is produced. Designing an automated system for regulating blood glucose in patients with diabetes is a solution that researchers have been paying close attention to in recent years. Therefore, safety is the minimum requirement for safety-critical systems such as the artificial pancreas. The present study introduces a safe, robust, performance-guaranteed optimal controller that can

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Scheel, Andreas A., Bettina Funsch, Michael Busch, Gabriele Gradl, Johannes Pschorr, and Martin J. Lohse. "Receptor-Ligand Interactions Studied with Homogeneous Fluorescence-Based Assays Suitable for Miniaturized Screening." Journal of Biomolecular Screening 6, no. 1 (2001): 11–18. http://dx.doi.org/10.1177/108705710100600103.

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Cell membrane receptors play a central role in controlling cellular functions, making them the target of drugs for a wide variety of diseases. This report describes how a recently developed method, fluorescence intensity distribution analysis (FIDA), can be used to develop homogeneous, nonradioactive high throughput screening assays for membrane receptors. With FIDA, free ligand and ligand accumulated on receptor-bearing membrane vesicles can be distinguished on the basis of their particle brightness. This allows the concentration of both bound and free ligand to be determined reliably from a

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Logoyda, L. S. "ACADEMIC PLAGIARISM: IMPACT OF ACADEMIC INTEGRITY ON THE QUALITY OF HIGHER PHARMACEUTICAL EDUCATION." Медична освіта, no. 3 (December 3, 2019): 44–51. http://dx.doi.org/10.11603/me.2414-5998.2019.3.10647.

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The article adduces the ways to solve the main problems faced by faculty stuff and students regarding academic plagiarism in higher pharmaceutical education. The development of information technologies, globalization processes in education, facilitating access to a large massive of data, research and publications updated the need for formulation and observance of moral and ethical principles regarding the use of information in the academic sphere. The research is based on the study of materials obtained from open sources of information and authors’ own experience. Program for checking th

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Bezeredi, Slavko. "Isplativost rada u Hrvatskoj i Sloveniji: analiza pomoću mikrosimulacijskog modela." Revija za socijalnu politiku 28, no. 2 (2021): 163–85. http://dx.doi.org/10.3935/rsp.v28i2.1787.

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WORK INCENTIVES IN CROATIA AND SLOVENIA: ANALYSIS USING MICROSIMULATION MODELS The paper analyzes the impact of the tax-benefit system on work incentives in Croatia and Slovenia. Unemployed and inactive persons and their hypothetical transitions to employment are considered. As the main indicator of work incentives, the participation tax rate (PTR) is estimated, as it represents a portion of additional income that is lost because taxes increase and benefits decrease in transition of a person from non-employment into employment. Unlike previous research, which was made for both countries on hyp

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Deeb, Samir, Mrwan BenIdris, Hany Ammar, and Dale Dzielski. "Refactoring Cost Estimation for Architectural Technical Debt." International Journal of Software Engineering and Knowledge Engineering 31, no. 02 (2021): 269–88. http://dx.doi.org/10.1142/s021819402150008x.

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Paying-off the Architectural Technical Debt by refactoring the flawed code is important to control the debt and to keep it as low as possible. Project Managers tend to delay paying off this debt because they face difficulties in comparing the cost of the refactoring against the benefits gained. These managers need to estimate the cost and the efforts required to conduct these refactoring activities as well as to decide which flaws have higher priority to be refactored. Our research is based on a dataset used by other researchers that study the technical debt. It includes more than 18,000 refac

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Cardullo, Victoria, Chih-hsuan Wang, Megan Burton, and Jianwei Dong. "K-12 teachers’ remote teaching self-efficacy during the pandemic." Journal of Research in Innovative Teaching & Learning 14, no. 1 (2021): 32–45. http://dx.doi.org/10.1108/jrit-10-2020-0055.

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PurposeThe purpose of this study was to examine the relationship between factors in the extended technology acceptance model (TAM) model and teachers' self-efficacy in remote teaching during the COVID-19 pandemic. In addition, the authors sought to listen to classroom teachers as they expressed their unbiased views of the advantages, disadvantages and challenges of teaching remotely during the COVID-19 pandemic.Design/methodology/approachA survey was employed to examine the relationship between factors in the extended TAM model and teachers' self-efficacy in remote teaching during the COVID-19

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Wulkow, Hanna, Tim O. F. Conrad, Nataša Djurdjevac Conrad, Sebastian A. Müller, Kai Nagel, and Christof Schütte. "Prediction of Covid-19 spreading and optimal coordination of counter-measures: From microscopic to macroscopic models to Pareto fronts." PLOS ONE 16, no. 4 (2021): e0249676. http://dx.doi.org/10.1371/journal.pone.0249676.

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The Covid-19 disease has caused a world-wide pandemic with more than 60 million positive cases and more than 1.4 million deaths by the end of November 2020. As long as effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, self-isolation and quarantine as well as far-reaching shutdowns of economic activity and public life are the only available strategies to prevent the virus from spreading. These interventions must meet conflicting requirements where some objectives, like the minimization of disease-related deaths or the impa

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Tsyrulnyk, Serhii. "THE USE OF AUGMENTED REALITY TECHNOLOGY IN THE PROCESS OF TRAINING SPECIALISTS IN ELECTRONICS." OPEN EDUCATIONAL E-ENVIRONMENT OF MODERN UNIVERSITY, SPECIAL EDITION (2019): 355–62. http://dx.doi.org/10.28925/2414-0325.2019s32.

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Modern teaching methods are implemented with the use of information technologies that facilitate and accelerate the transfer of knowledge to students, increase student motivation and increase the level of assimilation of information through diversity and interactivity of its visual representation. Today, there are many approaches to using augmented reality technology in education. Such learning system can be divided into three basic groups: visualization of 3D images for a visual representation of training material; recognition and marking of real objects, which are oriented in space; the inte

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Yilmaz, Siobhan K., Brady P. Horn, Chris Fore, and Caroline A. Bonham. "An economic cost analysis of an expanding, multi-state behavioural telehealth intervention." Journal of Telemedicine and Telecare 25, no. 6 (2018): 353–64. http://dx.doi.org/10.1177/1357633x18774181.

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Introduction In this paper the economic costs associated with a growing, multi-state telepsychiatry intervention serving rural American Indian/Alaska Native populations were compared to costs of travelling to provide/receive in-person treatment. Methods Telepsychiatry costs were calculated using administrative, information-technology, equipment and technology components, and were compared to travel cost models. Both a patient travel and a psychiatrist travel model were estimated utilising ArcGIS software and unit costs gathered from literature and government sources. Cost structure and sensiti

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Ruska, Ruslana. "MODELLING THE DYNAMICS OF PENSION CONTRIBUTIONS ACCUMULATION IN NON-GOVERNMENTAL PENSION FUNDS." Economic Analysis, no. 28(4) (2018): 106–13. http://dx.doi.org/10.35774/econa2018.04.106.

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Introduction. Pension provision in any country depends both on the state of the national economy and on the state regulation of social processes. The solidarity pension system in Ukraine does not provide a decent standard of living. Alternative, which allows creating an additional source of pension benefits, which are guaranteed by the state, and reducing the financial burden on the state, are non-state pension funds. Non-state pension funds provide non-state pension provision services by individualizing the accumulation of funds. Their main purpose is to ensure that people receive additional

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Wei, Zhihua, Jie Huang, Jing Li, Junshan Li, Xuyang Liu, and Xingsheng Ni. "A Compact Double-Folded Substrate Integrated Waveguide Re-Entrant Cavity for Highly Sensitive Humidity Sensing." Sensors 19, no. 15 (2019): 3308. http://dx.doi.org/10.3390/s19153308.

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In this study, an ultra-compact humidity sensor based on a double-folded substrate integrated waveguide (SIW) re-entrant cavity was proposed and analyzed. By folding a circular re-entrant cavity twice along its two orthogonally symmetric planes, the designed structure achieved a remarkable size reduction (up to 85.9%) in comparison with a conventional TM010-mode circular SIW cavity. The operating principle of the humidity sensor is based on the resonant method, in other words, it utilizes the resonant properties of the sensor as signatures to detect the humidity condition of the ambient enviro

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Campbell, Angela, and Gillian Nycum. "Harmonizing the International Regulation of Embryonic Stem Cell Research: Possibilities, Promises and Potential Pitfalls." Medical Law International 7, no. 2 (2005): 113–48. http://dx.doi.org/10.1177/096853320500700202.

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Despite near unanimous global opposition to human reproductive cloning, the United Nations has been unable to reach a consensus as to how cloning practices should be regulated at the international level. As a result, the U.N. objective of establishing binding international regulations governing cloning and stem cell research has yet to be achieved. Given the lack of consensus that exists within the global community on this topic, it seems that any attempt to harmonize the international regulation of cloning and stem cell science will face important obstacles. This paper seeks to illuminate the

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Laksmitawati, Dian Ratih, Liliek Nurhidayati, Mochamad Futuchul Arifin, and Bagus Bahtiar. "Optimasi Konsentrasi Ekstrak dan Bahan Pengikat Polivinil Pirolidon pada Granul Ekstrak Daun Sirih Merah (Piper crocatum Ruiz & Pav) sebagai Antihiperurisemia." JURNAL ILMU KEFARMASIAN INDONESIA 15, no. 2 (2017): 216. http://dx.doi.org/10.35814/jifi.v15i2.527.

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Ethanolic extract of red betel leaves (Piper crocatum Ruiz & Pav) has antihyperuricemic activity. In order to be applicable to consume, this extract need to be formulated into pharmaceutical dosage form. Granules which is packed in a tea sac bag was considered to be more practical andappropriate for person suff ering hyperuricemic, because they have to drink more water. In the granulation process, the he binder plays an important role so that this study aims to fi nd the optimal red betel leaf granule formula with variation on the extract dose and the polyvinyl pyrolidone (PVP) binder and

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Zafari, Zafar, Boshen Jiao, Brian Will, Shukai Li, and Peter Muennig. "The Trade-Off between Optimizing Flight Patterns and Human Health: A Case Study of Aircraft Noise in Queens, NY, USA." International Journal of Environmental Research and Public Health 15, no. 8 (2018): 1753. http://dx.doi.org/10.3390/ijerph15081753.

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Objectives: Airports in the U.S. have gradually been transitioning to automated flight systems. These systems generate new flight paths over populated areas. While they can improve flight efficiency, the increased noise associated with these novel flight patterns potentially pose serious health threats to the overflown communities. In this case study, we estimated the monetary benefits relative to health losses associated with one significant change in flight patterns at LaGuardia Airport, year-round use of “TNNIS Climb”, which happened in 2012 as a result of flight automation in New York City

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Lupiáñez-Villanueva, Francisco, Frans Folkvord, and Mariek Vanden Abeele. "Influence of the Business Revenue, Recommendation, and Provider Models on Mobile Health App Adoption: Three-Country Experimental Vignette Study." JMIR mHealth and uHealth 8, no. 6 (2020): e17272. http://dx.doi.org/10.2196/17272.

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Background Despite the worldwide growth in mobile health (mHealth) tools and the possible benefits of mHealth for patients and health care providers, scientific research examining factors explaining the adoption level of mHealth tools remains scarce. Objective We performed an experimental vignette study to investigate how four factors related to the business model of an mHealth app affect its adoption and users’ willingness to pay: (1) the revenue model (ie, sharing data with third parties vs accepting advertisements); (2) the data protection model (General Data Protection Regulation [GDPR]-co

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Lessing, Charon, Toni Ashton, and Peter Davis. "New Zealand patients’ understanding of brand substitution and opinions on copayment options for choice of medicine brand." Australian Health Review 40, no. 3 (2016): 345. http://dx.doi.org/10.1071/ah15004.

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Objective The aim of the present study was to better understand the views and experiences of New Zealand patients on switching between brands of prescription medicines and on alternative funding options for the provision of medicines, including an increase in copayments. Methods A self-administered questionnaire was offered to selected patients through participating community pharmacies. Pharmacies were stratified according to level of deprivation of the community served before random selection and invitation for involvement in the study. Patient understanding of and rationale for brand substi

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