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1

García-Estela, Aitana, Natalia Angarita-Osorio, Sandra Alonso, Maria Polo, Maria Roldán-Berengué, Monique Messaggi-Sartor, Estanislao Mur-Mila, et al. "Improving Depressive Symptoms through Personalised Exercise and Activation (IDEA): Study Protocol for a Randomised Controlled Trial." International Journal of Environmental Research and Public Health 18, no. 12 (June 10, 2021): 6306. http://dx.doi.org/10.3390/ijerph18126306.

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Individuals who suffer from depressive symptoms experience a substantial impact on psychosocial functioning, physical health, mortality, and quality of life. In the search for therapeutic strategies, exercise has been found to play a relevant part in its treatment. However, the promotion of exercise entails adherence difficulties that arose out of the tendency towards sedentarism led by symptomatology. Personalised exercise plans on top of usual care have the potential to enhance behavioural changes and mental health. The present study aims at evaluating the changes in functioning deriving from a blended intervention merging a psychological intervention with a personalised exercise programme based on medical assessment. We will conduct a three-arm randomised controlled trial in which 172 participants suffering from mild–moderate depressive symptoms will be allocated to Intervention A (personalised exercise group programme + app with motivational messages), B (personalised exercise group programme + app with no motivational messages) or control group (app with no motivational messages). Data regarding global functioning, well-being, symptoms, physical activity, and exercise capacity will be collected at baseline, 4, 12, and 36 weeks. The results of this trial will provide information about whether this physical activity support programme may be efficient for improving mental and physical health outcomes. Trial registration: ClinicalTrials.gov NCT04857944 (accessed on 15 April 2021). Registered April 2021.
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Rodgers, Geraldine, Anne Mottley, and Diana Hodgins. "Novel Digital Gait Kinematic Solution to Improve Frailty." Journal of Biomedical Engineering and Medical Imaging 7, no. 5 (October 31, 2020): 01–10. http://dx.doi.org/10.14738/jbemi.75.8894.

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Introduction: Frailty effects a person’s health and correlates with mobility and falls. Intervention studies that focus on exercise have demonstrated improved mobility and functional ability in some frailty groups. This study tested a personalised intervention programme automatically generated from digital gait data on frail older people under the care of the North East London Foundation Trust, Community Hospital setting. Methods: One hundred and twenty one people, average age 79, who suffered an injurious fall and were under the care of the Community Hospital, completed the personalised intervention programme. Objective gait kinematic data, obtained using GaitSmartTM automatically generated a personalised exercise programme. Each participant received four tests, approximately 3 weeks apart and was provided with a copy of their report plus personalised exercises. Frailty was measured using the Edmonton Frailty Scale (EFS), fear of falling was measured using the Falls Efficacy Scale-International (FES-I) and speed was determined from the gait data (GS). Results: Five parameters were analysed for all 121 participants at the start and end of the intervention: EFS; FES-I; GS; speed; walking aid. There was a statistically significance between the start and end (p<0.001) for all the parameters. Conclusion: The results demonstrate that addressing frailty using a digital gait solution that sets exercises based on the gait kinematic data, did reverse frailty. This four session programme has shown to improve frailty levels and fear of falling. It also reduced the reliance on walking aids and increased average walking speed from 0.46 to 0.62 m/s.
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Jones, Helen, Keith P. George, Andrew Scott, John P. Buckley, Paula M. Watson, David L. Oxborough, Dick H. Thijssen, et al. "Charter to establish clinical exercise physiology as a recognised allied health profession in the UK: a call to action." BMJ Open Sport & Exercise Medicine 7, no. 3 (September 2021): e001158. http://dx.doi.org/10.1136/bmjsem-2021-001158.

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The UK population is growing, ageing and becoming increasingly inactive and unfit. Personalised and targeted exercise interventions are beneficial for ageing and the management of chronic and complex conditions. Increasing the uptake of effective exercise and physical activity (PA) interventions is vital to support a healthier society and decrease healthcare costs. Current strategies for exercise and PA at a population level mostly involve self-directed exercise pathways, delivered largely via the fitness industry. Even for those who opt-in and manage to achieve the current recommendations regarding minimum PA, this generic ‘one-size-fits-all’ approach often fails to demonstrate meaningful physiological and health benefits. Personalised exercise prescription and appropriate exercise testing, monitoring and progression of interventions for individuals with chronic disease should be provided by appropriately trained and recognised exercise healthcare professionals, educated in the cognate disciplines of exercise science (eg, physiology, biomechanics, motor control, psychology). This workforce has operated for >20 years in the Australian public and private healthcare systems. Accredited exercise physiologists (AEPs) are recognised allied health professionals, with demonstrable health and economic benefits. AEPs have knowledge of the risks and benefits of distinct forms of exercise, skills in the personalised prescription and optimal delivery of exercise, and competencies to support sustained PA behavioural change, based on the established scientific evidence. In this charter, we propose a road map for the training, accreditation and promotion of a clinical exercise physiology profession in the UK.
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Costa, Angelo, Ester Martinez-Martin, Miguel Cazorla, and Vicente Julian. "PHAROS—PHysical Assistant RObot System." Sensors 18, no. 8 (August 11, 2018): 2633. http://dx.doi.org/10.3390/s18082633.

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The great demographic change leading to an ageing society demands technological solutions to satisfy the increasing varied elderly needs. This paper presents PHAROS, an interactive robot system that recommends and monitors physical exercises designed for the elderly. The aim of PHAROS is to be a friendly elderly companion that periodically suggests personalised physical activities, promoting healthy living and active ageing. Here, it is presented the PHAROS architecture, components and experimental results. The architecture has three main strands: a Pepper robot, that interacts with the users and records their exercises performance; the Human Exercise Recognition, that uses the Pepper recorded information to classify the exercise performed using Deep Leaning methods; and the Recommender, a smart-decision maker that schedules periodically personalised physical exercises in the users’ agenda. The experimental results show a high accuracy in terms of detecting and classifying the physical exercises (97.35%) done by 7 persons. Furthermore, we have implemented a novel procedure of rating exercises on the recommendation algorithm. It closely follows the users’ health status (poor performance may reveal health problems) and adapts the suggestions to it. The history may be used to access the physical condition of the user, revealing underlying problems that may be impossible to see otherwise.
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Tuka, Vladimír, and Aleš Linhart. "Personalised exercise prescription: Finding the best for our patients." European Journal of Preventive Cardiology 27, no. 13 (October 22, 2019): 1366–68. http://dx.doi.org/10.1177/2047487319884376.

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Gevaert, Andreas B., Volker Adams, Martin Bahls, T. Scott Bowen, Veronique Cornelissen, Marcus Dörr, Dominique Hansen, et al. "Towards a personalised approach in exercise-based cardiovascular rehabilitation: How can translational research help? A ‘call to action’ from the Section on Secondary Prevention and Cardiac Rehabilitation of the European Association of Preventive Cardiology." European Journal of Preventive Cardiology 27, no. 13 (October 4, 2019): 1369–85. http://dx.doi.org/10.1177/2047487319877716.

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The benefit of regular physical activity and exercise training for the prevention of cardiovascular and metabolic diseases is undisputed. Many molecular mechanisms mediating exercise effects have been deciphered. Personalised exercise prescription can help patients in achieving their individual greatest benefit from an exercise-based cardiovascular rehabilitation programme. Yet, we still struggle to provide truly personalised exercise prescriptions to our patients. In this position paper, we address novel basic and translational research concepts that can help us understand the principles underlying the inter-individual differences in the response to exercise, and identify early on who would most likely benefit from which exercise intervention. This includes hereditary, non-hereditary and sex-specific concepts. Recent insights have helped us to take on a more holistic view, integrating exercise-mediated molecular mechanisms with those influenced by metabolism and immunity. Unfortunately, while the outline is recognisable, many details are still lacking to turn the understanding of a concept into a roadmap ready to be used in clinical routine. This position paper therefore also investigates perspectives on how the advent of ‘big data’ and the use of animal models could help unravel inter-individual responses to exercise parameters and thus influence hypothesis-building for translational research in exercise-based cardiovascular rehabilitation.
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Martínez-Rodríguez, Alejandro, Daniela Alejandra Loaiza-Martínez, Javier Sánchez-Sánchez, Jacobo Á. Rubio-Arias, Fernando Alacid, Soledad Prats-Moya, María Martínez-Olcina, Rodrigo Yáñez-Sepúlveda, and Pablo J. Marcos-Pardo. "Personalised Nutritional Plan and Resistance Exercise Program to Improve Health Parameters in Celiac Women." Foods 11, no. 20 (October 17, 2022): 3238. http://dx.doi.org/10.3390/foods11203238.

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Celiac disease (CD) is a permanent immune reaction to gluten in those with a genetic predisposition. This study was designed to evaluate menopause-associated symptoms, mood, bone quality, and IgA antibody levels in women with CD, untreated and treated with a gluten-free diet (GFD), and with or without resistance exercise. The randomised controlled trial was conducted on 28 Spanish women (>40 years old). Participants were divided into the following intervention groups: personalised gluten-free nutrition plan + exercise (GFD + E); personalised gluten-free nutrition plan (GFD); celiac controls (NO-GFD); and non-celiac controls (CONTROL). The participants responded to the Menopause Rating Scale and the Profile of Mood States (POMS) questionnaires. Bone quality was measured with ultrasound and IgA with a blood test. After 12 weeks of intervention, the GFD + E group showed significant improvement in urogenital symptoms and scored higher on the ‘vigour’ subscale of the POMS. Negative associations were found between the total score on the Menopause Rating Scale and the ‘vigour’ subscale of the POMS questionnaire. Only those women who underwent a personalised GFD nutritional intervention combined with resistance exercise demonstrated significant changes after the intervention.
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Ulrich, Cornelia M., Caroline Himbert, Kenneth Boucher, David W. Wetter, Rachel Hess, Jaewhan Kim, Kelly Lundberg, et al. "Precision-Exercise-Prescription in patients with lung cancer undergoing surgery: rationale and design of the PEP study trial." BMJ Open 8, no. 12 (December 2018): e024672. http://dx.doi.org/10.1136/bmjopen-2018-024672.

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IntroductionLung cancer is a significant burden on societies worldwide, and the most common cause of death in patients with cancer overall. Exercise intervention studies in patients with lung cancer have consistently shown benefits with respect to physical and emotional functioning. However, to date, exercise training has not been consistently implemented into clinical practice given that interventions have been costly and not aligned with clinical care.Methods/designThe Precision-Exercise-Prescription (PEP) study is a prospective randomised controlled trial comparing the effectiveness and feasibility of a personalised intervention exercise programme among patients with lung cancer undergoing surgery. Two-hundred patients who are diagnosed with stage primary or secondary lung cancer and are eligible to undergo surgical treatment at Huntsman Cancer Institute comprise the target population. Patients are randomised to either the (1) outpatient precision-exercise intervention group or (2) delayed intervention group. The intervention approach uses Motivation and Problem Solving, a hybrid behavioural treatment based on motivational interviewing and practical problem solving. The dosage of the exercise intervention is personalised based on the individual’s Activity Measure for Post-Acute-Care outpatient basic mobility score, and incorporates four exercise modes: mobility, callisthenics, aerobic and resistance. Exercise is implemented by physical therapists at study visits from presurgery until 6 months postsurgery. The primary endpoint is the level of physical function assessed by 6 min walk distance at 2 months postsurgery. Secondary outcomes include patient-reported outcomes (eg, quality of life, fatigue and self-efficacy) and other clinical outcomes, including length of stay, complications, readmission, pulmonary function and treatment-related costs up to 6 months postsurgery.Ethics/disseminationThe PEP study will test the clinical effectiveness and feasibility of a personalised exercise intervention in patients with lung cancer undergoing surgery. Outcomes of this clinical trial will be presented at national and international conferences and symposia and will be published in international, peer-reviewed journals. Ethics approval was obtained at the University of Utah (IRB 00104671).Trial registration numberNCT03306992.
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Lv, Pin, Xiaoxin Wang, Jia Xu, and Junbin Wang. "Intelligent personalised exercise recommendation: A weighted knowledge graph‐based approach." Computer Applications in Engineering Education 29, no. 5 (February 15, 2021): 1403–19. http://dx.doi.org/10.1002/cae.22395.

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Dedov, V., and I. Dedova. "Expressing personalised exercise doses in the daily energy expenditure equivalents." Journal of Science and Medicine in Sport 18 (December 2014): e34. http://dx.doi.org/10.1016/j.jsams.2014.11.220.

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Denning, J., and N. Hunter. "Cancer recovery and a personalised exercise service: a preliminary analysis." Physiotherapy 103 (December 2017): e102. http://dx.doi.org/10.1016/j.physio.2017.11.075.

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Wang, Honggang, Yisu Wang, Zengmin He, Xuzhi Li, and Yufeng Yao. "Personalised healthcare and exercise rehabilitation based on upper-limb metrics." Engineering Applications of Artificial Intelligence 151 (July 2025): 110673. https://doi.org/10.1016/j.engappai.2025.110673.

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Ross, Robert, Bret H. Goodpaster, Lauren G. Koch, Mark A. Sarzynski, Wendy M. Kohrt, Neil M. Johannsen, James S. Skinner, et al. "Precision exercise medicine: understanding exercise response variability." British Journal of Sports Medicine 53, no. 18 (March 12, 2019): 1141–53. http://dx.doi.org/10.1136/bjsports-2018-100328.

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There is evidence from human twin and family studies as well as mouse and rat selection experiments that there are considerable interindividual differences in the response of cardiorespiratory fitness (CRF) and other cardiometabolic traits to a given exercise programme dose. We developed this consensus statement on exercise response variability following a symposium dedicated to this topic. There is strong evidence from both animal and human studies that exercise training doses lead to variable responses. A genetic component contributes to exercise training response variability.In this consensus statement, we (1) briefly review the literature on exercise response variability and the various sources of variations in CRF response to an exercise programme, (2) introduce the key research designs and corresponding statistical models with an emphasis on randomised controlled designs with or without multiple pretests and post-tests, crossover designs and repeated measures designs, (3) discuss advantages and disadvantages of multiple methods of categorising exercise response levels—a topic that is of particular interest for personalised exercise medicine and (4) outline approaches that may identify determinants and modifiers of CRF exercise response. We also summarise gaps in knowledge and recommend future research to better understand exercise response variability.
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Yanagi, Hidetoshi, Harumi Konishi, Saori Yamada, Kazuya Yamamoto, and Fumiyuki Otsuka. "Stepwise cardiac rehabilitation adjustment after exercise-induced implantable cardioverter defibrillator shock: a case report." Journal of Rehabilitation Medicine - Clinical Communications 8 (April 16, 2025): jrmcc42483. https://doi.org/10.2340/jrm-cc.v8.42483.

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Objective: To report an in-hospital cardiac rehabilitation strategy after exercise-induced implantable cardioverter defibrillator shock. Case report: A 72-year-old man with heart failure, peripheral artery disease, a history of percutaneous coronary intervention and coronary artery bypass surgery, exercise-induced ventricular fibrillation, and an implantable cardioverter defibrillator was hospitalised after experiencing recurrent ventricular fibrillation while walking, which triggered implantable cardioverter defibrillator shock. While hospitalised, his medication regimen was adjusted. After passing the 200-m walking test, he started in-hospital cardiac rehabilitation. During cardiopulmonary exercise testing, he experienced non-sustained ventricular tachycardia. Percutaneous coronary intervention was performed to relieve ischaemia; however, ventricular tachycardia recurred during walking, causing another implantable cardioverter defibrillator shock. After further medication adjustments and setting heart rate limits, he gradually resumed cycling and low-intensity resistance exercises, followed by walking, and was subsequently discharged without ventricular tachycardia recurrence. Discussion: Peripheral artery disease-associated pain and increased heart rate may have contributed to ventricular tachycardia. A stepwise exercise programme involving heart rate monitoring and medication therapy adjustments enabled safe exercise resumption after implantable cardioverter defibrillator shock in a patient with multiple comorbidities. Conclusion: This case emphasises the importance of personalised exercise strategies that consider both arrhythmic risk and comorbidities for patients at high risk of exercise-induced arrhythmias.
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Hyatt, Amelia, Karla Gough, Andrew Murnane, George Au-Yeung, Tamara Dawson, Elizabeth Pearson, Haryana Dhillon, et al. "i-Move, a personalised exercise intervention for patients with advanced melanoma receiving immunotherapy: a randomised feasibility trial protocol." BMJ Open 10, no. 2 (February 2020): e036059. http://dx.doi.org/10.1136/bmjopen-2019-036059.

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IntroductionThere is increasing evidence demonstrating the benefits of exercise in counteracting cancer treatment-related fatigue. Immunotherapy is an established treatment for advanced melanoma, and is associated with fatigue in a third of patients. The safety and efficacy of exercise in counteracting treatment-related fatigue in patients with advanced melanoma receiving immunotherapy are yet to be determined. This study aims to assess the safety, adherence to and acceptability of a mixed-methods parallel-group, pilot randomised controlled trial of a personalised, 12-week semi-supervised exercise programme prescribed by an exercise physiologist (iMove) in 30 patients with stage IV melanoma scheduled to commence immunotherapy: single agent ipilimumab, nivolumab or pembrolizumab, or combination ipilimumab and nivolumab. The trial will be used to provide preliminary evidence of the potential efficacy of exercise for managing fatigue.Methods and analysisThirty participants will be recruited from a specialist cancer centre between May and September, 2019. Participants will be randomised 1:1 to receive iMove, or usual care (an information booklet about exercise for people with cancer). Feasibility data comprise: eligibility; recruitment and retention rates; adherence to and acceptability of exercise consultations, personalised exercise programme and study measures; and exercise-related adverse events. Patient-reported outcome measures assess potential impact of the exercise intervention on: fatigue, role functioning, symptoms and quality of life. Follow-up will comprise five time points over 24 weeks. Physical assessments measure physical fitness and functioning.Ethics and disseminationThis study was reviewed and approved by the Peter MacCallum Cancer Centre Human Research Ethics Committee (HREC/48927/PMCC-2019). The findings from this trial will be disseminated via conference presentations and publications in peer-reviewed journals, and by engagement with clinicians, media, government and consumers. In particular, we will promote the outcomes of this work among the oncology community should this pilot indicate benefit for patients.Trial registration numberACTRN12619000952145; Pre-results.
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Oliva, F., M. N. Agnes, M. Castellano Vitaterna, and N. Maffulli. "Low Back Pain in Weightlifters: Personalised Exercise Protocols for Elite Athletes." Muscle Ligaments and Tendons Journal 13, no. 02 (June 2023): 187. http://dx.doi.org/10.32098/mltj.02.2023.01.

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O’Reilly, Martin A., Tomás E. Ward, Eamonn Delahunt, Brian Caulfield, and Darragh F. Whelan. "Technology in Rehabilitation: Comparing Personalised and Global Classification Methodologies in Evaluating the Squat Exercise with Wearable IMUs." Methods of Information in Medicine 56, no. 05 (2017): 361–69. http://dx.doi.org/10.3414/me16-01-0141.

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SummaryBackground: The barbell squat is a popularly used lower limb rehabilitation exercise. It is also an integral exercise in injury risk screening protocols. To date athlete/patient technique has been assessed using expensive laboratory equipment or subjective clinical judgement; both of which are not without shortcomings. Inertial measurement units (IMUs) may offer a low cost solution for the objective evaluation of athlete/patient technique. However, it is not yet known if global classification techniques are effective in identifying naturally occurring, minor deviations in barbell squat technique.Objectives: The aims of this study were to: (a) determine if in combination or in isolation, IMUs positioned on the lumbar spine, thigh and shank are capable of distinguishing between acceptable and aberrant barbell squat technique; (b) determine the capabilities of an IMU system at identifying specific natural deviations from acceptable barbell squat technique; and (c) compare a personalised (N=1) classifier to a global classifier in identifying the above.Methods: Fifty-five healthy volunteers (37 males, 18 females, age = 24.21 +/- 5.25 years, height = 1.75 +/- 0.1 m, body mass = 75.09 +/- 13.56 kg) participated in the study. All participants performed a barbell squat 3-repeti- tion maximum max strength test. IMUs were positioned on participants’ lumbar spine, both shanks and both thighs; these were utilized to record tri-axial accelerometer, gyroscope and magnetometer data during all repetitions of the barbell squat exercise. Technique was assessed and labelled by a Chartered Physiotherapist using an evaluation framework. Features were extracted from the labelled IMU data. These features were used to train and evaluate both global and personalised random forests classifiers.Results: Global classification techniques produced poor accuracy (AC), sensitivity (SE) and specificity (SP) scores in binary classification even with a 5 IMU set-up in both binary (AC: 64%, SE: 70%, SP: 28%) and multi- class classification (AC: 59%, SE: 24%, SP: 84%). However, utilising personalised classification techniques even with a single IMU positioned on the left thigh produced good binary classification scores (AC: 81%, SE: 81%, SP: 84%) and moderate-to-good multi- class scores (AC: 69%, SE: 70%, SP: 89%).Conclusions: There are a number of challenges in developing global classification exercise technique evaluation systems for rehabilitation exercises such as the barbell squat. Building large, balanced data sets to train such systems is difficult and time intensive. Minor, naturally occurring deviations may not be detected utilising global classification approaches. Personalised classification approaches allow for higher accuracy and greater system efficiency for end-users in detecting naturally occurring barbell squat technique deviations. Applying this approach also allows for a single-IMU set up to achieve similar accuracy to a multi-IMU setup, which reduces total system cost and maximises system usability.
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Pina, Ilaria, Pauline Ndagire, Winceslaus Katagira, Lorna Latimer, Jakub Zatloukal, Bruce Kirenga, Sally J. Singh, and Mark W. Orme. "Deriving personalised physical activity intensity thresholds by merging accelerometry with field-based walking tests: Implications for pulmonary rehabilitation." Chronic Respiratory Disease 19 (January 2022): 147997312211292. http://dx.doi.org/10.1177/14799731221129286.

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During pulmonary rehabilitation (PR), patients receive individually tailored walking exercise training. The personalised nature of exercise prescription is a fundamental component of PR. Despite this, the measurement of physical activity (PA) has been limited to a ‘one size fits all’ approach and can be challenging to translate into clinically meaningful or real-world units, such as cadence. This discrepancy may partly explain the inconsistent evidence for the impact of PR on PA. It may also provide an opportunity to standardise PA assessment in the context of chronic respiratory disease (CRD) and PR, where field-based walking tests are routine measures. This technical note provides an example of how to develop personalised PA intensity thresholds, calibrated against an individual’s performance on the Incremental Shuttle Walking Test (ISWT; maximal) and Endurance Shuttle Walk Test (ESWT; sub-maximal). These are externally paced tests, with each level (speed) of the tests denoting a specific speed (intensity); ranging 1.8 km/h (ISWT Level 1) to 8.5 km/h (ISWT Level 12). From the ESWT, it becomes possible to evaluate adherence to each individual’s walking exercise prescription. Future research should explore this approach and its responsiveness to PR. It may be possible to extend this methodology with the inclusion of physiological parameters (e.g., heart rate, calorimetry, and oxygen consumption) to derive relative intensity markers (e.g. moderate-to-vigorous), accounting for individual differences in exercise capacity, under the same paradigm as PR exercise prescription.
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Gunisetty, Hari Prakash, Sunil Kumar Doddaiah, Kiran Pura Krishnamurthy, Vanishri Arun, Deepika Yadav, and Arun Gopi. "Personalised Oncology Care: A Case Study on Using an AI-Based App for Chemotherapy Management and Lifestyle Managemen." Asian Pacific Journal of Cancer Care 10, no. 2 (April 16, 2025): 649–51. https://doi.org/10.31557/apjcc.2025.10.2.649-651.

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This case report explores the use of Mebot, an AI-based mobile application, to enhance medication adherence and lifestyle management in a patient undergoing chemotherapy. Over one week, Mebot was utilised by a patient to manage a complex chemotherapy regimen, providing timely reminders for medication intake and generating personalised exercise plans to support weight reduction. The app’s “connected dots” functionality allowed for integrating related tasks like medication and exercise into a seamless health management approach. Multiple users, including the authors of this report, tested the app and reported consistent, satisfactory results, highlighting Mebot’s reliability and effectiveness. The study findings suggest that Mebot could be a valuable tool in managing non-communicable diseases (NCDs) by improving adherence to treatment protocols and supporting lifestyle interventions. However, further research involving more prominent and diverse populations is necessary to validate these preliminary observations and explore the broader applicability of AI-driven mobile applications in personalised oncology care.
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Kozior, Marta, Phillip M. Jakeman, and Catherine Norton. "Peri-training nutrition methods: advancements to dietary assessment in an athletic population." Applied Physiology, Nutrition, and Metabolism 45, no. 5 (May 2020): 564–68. http://dx.doi.org/10.1139/apnm-2019-0622.

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Key opinion leaders in sport and exercise nutrition advocate for a personalised and periodised approach to dietary assessment and prescription. However, practice has not advanced to this level, making recommendations from key researchers unexploited in the applied setting. Our objective was to advance traditional nutritional assessment methods (data collection and analysis) of athletic populations to place training and competition stimulus at the core of a personalised, periodised approach. We term this approach peri-training nutrition (PTN). Novelty The PTN assessment allows researchers and practitioners to effect monitor habitual nutritional practices of athletes specific to athlete aims, training adaptation stimuli, and competitive events.
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Knoll, R. L., J. Klopp, V. H. J. Diaz, K. Hilbert, B. Hillen, A. Kemper, S. Gruca, et al. "WS13.3 Microbiome composition during a personalised internet-supported exercise and nutrition program." Journal of Cystic Fibrosis 20 (2021): S25. http://dx.doi.org/10.1016/s1569-1993(21)00989-9.

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Angelidis, Pantelis A. "Personalised physical exercise regime for chronic patients through a wearable ICT platform." International Journal of Electronic Healthcare 5, no. 4 (2010): 355. http://dx.doi.org/10.1504/ijeh.2010.036207.

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Simpson, Sharon Anne, Rachael A. Evans, Hannah Rosemary Gilbert, Amy Branson, Shaun Barber, Emma McIntosh, Zahira Ahmed, et al. "Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM): protocol for a randomised feasibility trial." BMJ Open 14, no. 4 (April 2024): e083255. http://dx.doi.org/10.1136/bmjopen-2023-083255.

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IntroductionPersonalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM) is a research programme that seeks to develop and evaluate a comprehensive exercise-based rehabilitation intervention designed for people with multimorbidity, the presence of multiple long-term conditions (MLTCs). This paper describes the protocol for a randomised trial to assess the feasibility and acceptability of the PERFORM intervention, study design and processes.Methods and analysisA multicentre, parallel two-group randomised trial with individual 2:1 allocation to the PERFORM exercise-based intervention plus usual care (intervention) or usual care alone (control). The primary outcome of this feasibility trial will be to assess whether prespecified progression criteria (recruitment, retention, intervention adherence) are met to progress to the full randomised trial. The trial will be conducted across three UK sites and 60 people with MLTCs, defined as two or more LTCs, with at least one having evidence of the beneficial effect of exercise. The PERFORM intervention comprises an 8-week (twice a week for 6 weeks and once a week for 2 weeks) supervised rehabilitation programme of personalised exercise training and self-management education delivered by trained healthcare professionals followed by two maintenance sessions. Trial participants will be recruited over a 4.5-month period, and outcomes assessed at baseline (prerandomisation) and 3 months postrandomisation and include health-related quality of life, psychological well-being, symptom burden, frailty, exercise capacity, physical activity, sleep, cognition and serious adverse events. A mixed-methods process evaluation will assess acceptability, feasibility and fidelity of intervention delivery and feasibility of trial processes. An economic evaluation will assess the feasibility of data collection and estimate the costs of the PERFORM intervention.Ethics and disseminationThe trial has been given favourable opinion by the West Midlands, Edgbaston Research Ethics Service (Ref: 23/WM/0057). Participants will be asked to give full, written consent to take part by trained researchers. Findings will be disseminated via journals, presentations and targeted communications to clinicians, commissioners, service users and patients and the public.Trial registration numberNCT68786622.Protocol version2.0 (16 May 2023).
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Lathia, Tejal, Snehal Tanna, Mahesh Padsalge, Archana Juneja, Piya Ballani, Kirti Samudra, Sanjay Kalra, et al. "Significant Reduction in Hba1c and BMI After Three Months of Personalized Glycemic Response Based Coaching for Patients With Type 2 Diabetes." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A476. http://dx.doi.org/10.1210/jendso/bvab048.973.

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Abstract Background/Objective: Patients with type 2 diabetes face challenges when it comes to following recommendations (nutrition, exercise and medications). Using technology to understand glycemic responses can increase patient awareness about dietary and lifestyle changes. Coupled with coaching by an expert nutritionist, such a program may help improve patient adherence, resulting in a reduction in HbA1c and body mass index (BMI). Method: Fifty-seven patients with type 2 DM not at goal (HbA1c ≥ 6.5%) either on lifestyle modification, OHA with or without insulin, consenting to participate in the study were enrolled in the DIABEFLY program which included Ambulatory glucose monitoring (AGM) and correlating it with dietary intake for 14 days using a technology platform (FITTERFLY wellness app). Patients were explained their AGM graphs, in relation to their daily food and activity log, to make them aware of their personalised glycemic responses to various foods and accordingly diet plan was suggested. Nutritionists (coaches) interacted with patients over calls on Day 1, 7, 14, 30, 60 and Day 90 to explain recommendations, address any diabetes related queries and evaluate adherence to diet & exercise plans. Patients also had access to daily chat support for 90 days and received daily messages on glycemic responses, healthy food choices, exercise options, stress management, sleep, medication adherence, self-monitoring of blood glucose and complications of diabetes. Strictly, no advice on type or dosage of medication was given by the coaches. Statistical analysis for outcomes was done by t-test using SPSS software. Result: Out of 57 patients, mean age was 46 years, of which 70% were male and 30% were females. The baseline HbA1c was found to be 8.3% ± 1.68 which significantly decreased (p&lt;0.05) to 7.4% ± 1.36 in 3 months. The Baseline BMI of 27.1± 4.9 kg/ sq m was significantly reduced (p&lt;0.05) to 26.6±4.6 kg/sq m in 3 months. Discussion: With the availability of AGM devices, powerful food databases and technology to correlate these two had led to a new era of diabetes coaching. The personalised glycemic responses so calculated for every patient lead to more concrete understanding of changes necessary for better glycemic control. Regular interactions or reminders from an expert may act as a unique and necessary way of reinforcement to follow recommendations. In our study, though increased engagement with the programme resulted in a significant reduction in HbA1c and BMI. Conclusion: Personalized Glycemic response led coaching benefits patients with Type 2 diabetes mellitus helping them achieve two critical outcomes - lowering of HbA1c and reduction of BMI as early as three months. Keywords: AGM; Personalised glycemic response; Diabetes lifestyle coaching
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Buettikofer, Ms Tanya, Ms Allison Maher, Ms Veronica Rainbird, Ms Michelle Bennett, Associate Professor Nicole Freene, Professor Imogen Mitchell, Dr Hsin-Chia Carol Huang, et al. "CONSUMER EXPERIENCE OF AN AUSTRALIAN MULTIDISCIPLINARY LONG COVID CLINIC THAT INCORPORATES PERSONALISED EXERCISE PRESCRIPTION: A QUALITATIVE ANALYSIS." Journal of Clinical Exercise Physiology 13, s2 (May 1, 2024): 501. http://dx.doi.org/10.31189/2165-7629-13-s2.501.

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INTRODUCTION & AIMS Little is known about the Australian experience of Long COVID recovery, particularly with respect to exercise prescription. The aim of this study was to understand the consumer experience and acceptability of a novel Australian Long COVID Recovery Clinic that incorporates personalised exercise prescription, including respiratory and peripheral strengthening and carefully monitored cardiovascular training. METHODS Qualitative study; semi-structured interviews with a convenience sample of participants who have completed a multidisciplinary, individually-tailored and supervised programme at our Long COVID Recovery Clinic. Interviews were conducted by a researcher external to the clinic delivery. Major themes were identified by inductive thematic analysis. RESULTS 15 participants were interviewed. 14/15 (93%) participants described the clinic model as acceptable or highly acceptable. Five core themes were identified, including (1) encouraging staff and light-filled facilities are key to support recovery; (2) individually tailored, supervised exercise and pacing helped to improve confidence in building exercise capacity; (3) peer support and group therapy augments recovery; (4) recovery from Long COVID is incomplete, and other services augment the Long COVID Recovery Clinic model; and (5) importance of GP involvement in connection with clinic participation. Suggestions for improvement included extending the duration of the clinic programme beyond 2 months, reducing wait times by increasing staffing levels and adjusting the clinic schedule to broaden access options. CONCLUSION The majority of participants found the Long COVID Recovery Clinic, which incorporates both supervised exercise and pacing, acceptable and would recommend it to others. From the consumer perspective, the Long COVID Recovery Clinic aids recovery alongside GP management through a combination of peer support and an individually tailored program.
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Tomlinson, Owen W., James Shelley, Jayne Trott, Ben Bowhay, Rohan Chauhan, and Christopher D. Sheldon. "The feasibility of online video calling to engage patients with cystic fibrosis in exercise training." Journal of Telemedicine and Telecare 26, no. 6 (February 25, 2019): 356–64. http://dx.doi.org/10.1177/1357633x19828630.

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Introduction Physical activity, including structured exercise, is an essential component in the management of cystic fibrosis. The use of telehealth such as video-calling may be a useful method for the delivery of exercise and physical activity interventions, though the feasibility of this remains unknown. Methods Nine patients with cystic fibrosis (three female, six male, 30.9 ± 8.7 years) volunteered to participate. Participants completed an eight-week exercise training intervention conducted via Skype, using personalised exercises, with all sessions supervised by an exercise therapist. Feasibility was assessed by demand, implementation, practicality and acceptability. Changes in anthropometric, pulmonary, physical activity and quality of life variables were also assessed. Results Two male participants withdrew from the study, citing lack of available time. The remaining participants found use of Skype useful, with a mean satisfaction rating of 9/10, and three participants requesting to continue the sessions beyond the duration of the study. Mean compliance with sessions was 68%, with mean duration of sessions being 20 min. A total of 25% of calls suffered from technical issues such as video or audio lags. Anthropometric, pulmonary, physical activity and quality of life variables remained unchanged over the course of the study period. Discussion The use of Skype to deliver an exercise intervention to patients withcystic fibrosis was found to be technologically feasible, and acceptable among participants. Findings have implications for clinical practice and could allow care teams to engage patients remotely in exercise. Further research is required to assess the efficacy of this modality on increasing physical activity and associated health outcomes.
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Steinhausen, Kirsten, and Stephane Berghmans. "Key issues affecting the development and implementation of personalised medicine: a foresight exercise." Drug Discovery Today: Therapeutic Strategies 10, no. 4 (2013): e189-e194. http://dx.doi.org/10.1016/j.ddstr.2015.01.001.

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Bowhay, Ben, Craig A. Williams, Michael A. Gibbons, Chris J. Scotton, and Owen W. Tomlinson. "Exploring the potential of cardiopulmonary exercise testing (CPET) for individualised pulmonary rehabilitation in people with interstitial lung disease (ILD): A systematic review protocol." NIHR Open Research 4 (September 17, 2024): 51. http://dx.doi.org/10.3310/nihropenres.13706.1.

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Background This review aims to identify which cardiopulmonary exercise test (CPET) derived variables can be used to personalise pulmonary rehabilitation for people with interstitial lung diseases. A ‘one size fits all’ approach does not benefit every patient due to a multitude of unique characteristics, subsets and phenotypes. No condition specific personalised pulmonary rehabilitation guidelines exist in this area and exercise programme development is lacking. This leads to wide variation in the success within the literature and clinical practice. Methods MEDLINE, Embase, CINAHL, SPORTDiscus and the Cochrane Database of Systematic Reviews will be searched to identify studies that utilise CPET variables for PR development. Quality assessment is to be performed using the Critical Appraisal Skills Program (CASP) checklists for single cohort studies and randomised controlled studies. Discussion The primary outcomes found within the included studies for peak volume of oxygen consumption (VO2peak), work rate (WRpeak), oxygen consumption at anaerobic threshold (VO2-AT), heart rate and rate of perceived exertion (RPE) would help determine which variables are optimal for prescription success. Identification of reliable methods to personalise pulmonary rehabilitation for people with interstitial lung disease would enhance what is already known and potentially lead to best practice guideline development. Registration In accordance with the guidelines, this systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 07 May 2024 (registration number CRD42024543174).
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Qian, Xie, and Lin Xinmao. "A Practical Study on the Use of Exercise Prescription Teaching Mode in Physical Education Dance Courses in Colleges and Universities." International Journal of Religion 5, no. 11 (August 29, 2024): 8051–57. http://dx.doi.org/10.61707/vs83pc33.

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Study Aim. With the increasing interest and demand for physical dance among contemporary college students, the teaching mode of physical dance courses in colleges and universities needs to be explored and improved. The traditional teaching of physical education dance often lacks a personalised teaching mode, which leads to the limitation of students' interest and learning effect. This study aims to explore the teaching mode of physical education dance courses in colleges and universities, based on exercise prescription and incorporating personalised teaching practices, in order to improve students' learning effect and interest and promote their all-round development. Material and Methods. This paper mainly analyses the impact of applying exercise prescription teaching mode on college students' physical health indicators such as body form, physical function and physical quality in the teaching practice of sports dance courses through literature, questionnaire survey, experimental method, mathematical statistics and other research methods, with a view to providing corresponding theoretical basis for the physical and mental development of college students and the further development of sports dance in colleges and universities. Results. The results show that the teaching mode of exercise prescription has less impact on the physical form and physical function of college students, and more impact on physical quality, especially the endurance quality, flexibility quality and other physical quality indicators and levels have been significantly improved, and the physical health level of college students has been improved. Conclusions. The application of the exercise prescription teaching mode in the teaching practice of physical education dance courses has a positive impact on college students' body shape, physical fitness, cardiorespiratory fitness and psychological fitness, and therefore should be further popularised and promoted in colleges and universities.
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Freer, Christine L., Elena S. George, Sze-Yen Tan, Gavin Abbott, Tonya Paris, and Robin M. Daly. "Acceptability and perceptions of a 12-week telehealth exercise programme with dietary advice to increase plant-based protein in people with non-alcoholic fatty liver disease: a programme evaluation using mixed methods." BMJ Open 15, no. 3 (March 2025): e086604. https://doi.org/10.1136/bmjopen-2024-086604.

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ObjectivesTelehealth may offer a cost-effective, accessible and convenient healthcare service model; however, the acceptability, safety and perceptions of telehealth delivered lifestyle interventions in those with non-alcoholic fatty liver disease (NAFLD) is unknown.DesignThis was a mixed-methods evaluation of a telehealth delivered 12-week exercise, dietary support and behavioural change programme (Tele-ProEx).Setting and participants12 adults receiving the intervention (47–77 years) with NAFLD living in Australia.Outcome measuresParticipants were assessed postintervention via questionnaires to evaluate acceptability and satisfaction with the programme, usability (exercise app) and perceptions of safety. Semistructured interviews were also conducted, and qualitative thematic analysis was used to identify themes.ResultsParticipants reported moderate to high acceptability (overall mean±SD scores out of 5: exercise programme 3.9±0.5; dietary support to increase plant protein intake 4.0±0.7; behavioural modification 3.6±0.4). Satisfaction was high (overall mean score 3.7±0.3 out of 4), the programme was perceived as safe (overall mean score, 4.4±0.5 out of 5) and app usability was above average (mean score 75.6±5.2 out of 100). Thematic analysis revealed participants perceived telehealth as being comparable to face-to-face interactions with health professionals. Common exercise barriers were alleviated by the personalised programme, while participants with low previous exposure to plant protein foods found the dietary recommendations challenging. Social support and engagement were deemed important for supporting motivation and adherence.ConclusionsIn adults with NAFLD, a telehealth delivered multifaceted lifestyle programme was well accepted and perceived as safe, indicating telehealth offers a viable delivery model in this population. Key features important to participants were the personalised and flexible approach utilising engaging delivery methods that featured social support.Trial registration numberACTRN12621001706864.
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Casimiro-Andújar, Antonio Jesús, Ricardo Martín-Moya, María Maravé-Vivas, and Pedro Jesús Ruiz-Montero. "Effects of a Personalised Physical Exercise Program on University Workers Overall Well-Being: “UAL-Activa” Program." International Journal of Environmental Research and Public Health 19, no. 18 (September 9, 2022): 11331. http://dx.doi.org/10.3390/ijerph191811331.

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Background and objectives: Regular individualised physical exercise (PE) is a habit that not only has consequences for overall health (physical, emotional, social and mental) but can also have positive effects on organisations and institutions, as it helps workers to improve their personal balance and recover from the effort of their working day, showing higher levels of energy, commitment and productivity. The aim of this study was to understand the relationship between the practice of PE and well-being in personal life and at work, as well as job satisfaction, overall health and the assessment of the personal training service provided by final-year students studying for a degree in Physical Activity and Sport Sciences. Methods: This study used a qualitative research methodology. There were 25 employees of the University of Almeria (UAL) (M = 52.16 ± 9.55 years), divided into two focus groups and participating in the physical exercise program “UAL Activa”. Results: The following three main themes, based on the results, emerged: (a) social well-being during PE practice, (b) assessment of the personal training service and (c) physical exercise as an emotional benefit at work. Conclusion. The workers’ interventions have shown that participating in a personalised PE program led by a personal trainer can improve overall health and mood, with a very positive influence on the working environment.
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Teo, Pek Ling, Kim L. Bennell, Belinda Lawford, T. Egerton, Krysia Dziedzic, and Rana S. Hinman. "Patient experiences with physiotherapy for knee osteoarthritis in Australia—a qualitative study." BMJ Open 11, no. 3 (March 2021): e043689. http://dx.doi.org/10.1136/bmjopen-2020-043689.

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ObjectivePhysiotherapists commonly provide non-surgical care for people with knee osteoarthritis (OA). It is unknown if patients are receiving high-quality physiotherapy care for their knee OA. This study aimed to explore the experiences of people who had recently received physiotherapy care for their knee OA in Australia and how these experiences aligned with the national Clinical Care Standard for knee OA.DesignQualitative study using semistructured individual telephone interviews and thematic analysis, where themes/subthemes were inductively derived. Questions were informed by seven quality statements of the OA of the Knee Clinical Care Standard. Interview data were also deductively analysed according to the Standard.SettingParticipants were recruited from around Australia via Facebook and our research volunteer database.ParticipantsInterviews were conducted with 24 people with recent experience receiving physiotherapy care for their knee OA. They were required to be aged 45 years or above, had activity-related knee pain and any knee-related morning stiffness lasted no longer than 30 min. Participants were excluded if they had self-reported inflammatory arthritis and/or had undergone knee replacement surgery for the affected knee.ResultsSix themes emerged: (1) presented with a pre-existing OA diagnosis (prior OA care from other health professionals; perception of adequate OA knowledge); (2) wide variation in access and provision of physiotherapy care (referral pathways; funding models; individual vs group sessions); (3) seeking physiotherapy care for pain and functional limitations (knee symptoms; functional problems); (4) physiotherapy management focused on function and exercise (assessment of function; various types of exercises prescribed; surgery, medications and injections are for doctors; adjunctive treatments); (5) professional and personalised care (trust and/or confidence; personalised care) and (6) physiotherapy to postpone or prepare for surgery.ConclusionPatients’ experiences with receiving physiotherapy care for their knee OA were partly aligned with the standard, particularly regarding comprehensive assessment, self-management, and exercise.
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Buckley, Benjamin J. R., Signe S. Risom, Maxime Boidin, Gregory Y. H. Lip, and Dick H. J. Thijssen. "Atrial Fibrillation Specific Exercise Rehabilitation: Are We There Yet?" Journal of Personalized Medicine 12, no. 4 (April 10, 2022): 610. http://dx.doi.org/10.3390/jpm12040610.

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Regular physical activity and exercise training are integral for the secondary prevention of cardiovascular disease. Despite recent advances in more holistic care pathways for people with atrial fibrillation (AF), exercise rehabilitation is not provided as part of routine care. The most recent European Society of Cardiology report for AF management states that patients should be encouraged to undertake moderate-intensity exercise and remain physically active to prevent AF incidence or recurrence. The aim of this review was to collate data from primary trials identified in three systematic reviews and recent real-world cohort studies to propose an AF-specific exercise rehabilitation guideline. Collating data from 21 studies, we propose that 360–720 metabolic equivalent (MET)-minutes/week, corresponding to ~60–120 min of exercise per week at moderate-to-vigorous intensity, could be an evidence-based recommendation for patients with AF to improve AF-specific outcomes, quality of life, and possibly prevent long-term major adverse cardiovascular events. Furthermore, non-traditional, low-moderate intensity exercise, such as Yoga, seems to have promising benefits on patient quality of life and possibly physical capacity and should, therefore, be considered in a personalised rehabilitation programme. Finally, we discuss the interesting concepts of short-term exercise-induced cardioprotection and ‘none-response’ to exercise training with reference to AF rehabilitation.
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Knoll, R. L., B. Hillen, S. Wirsching, J. Klopp, A. Kemper, S. Gruca, V. Bähner, S. Gehring, O. Nitsche, and K. Poplawska. "P179 A personalised internet-supported exercise and nutrition program increases Resolvin-D1 plasma levels." Journal of Cystic Fibrosis 19 (June 2020): S106—S107. http://dx.doi.org/10.1016/s1569-1993(20)30514-2.

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Gloeckl, Rainer, Fabio Pitta, and Andre Nyberg. "Optimising upper-limb exercise in patients with COPD: another step towards personalised pulmonary rehabilitation?" ERJ Open Research 10, no. 1 (January 2024): 01012–2023. http://dx.doi.org/10.1183/23120541.01012-2023.

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Kritikaki, Efpraxia, Rhiannon Asterling, Lesley Ward, Kay Padget, Esther Barreiro, and Davina C. M. Simoes. "Exercise Training-Induced Extracellular Matrix Protein Adaptation in Locomotor Muscles: A Systematic Review." Cells 10, no. 5 (April 26, 2021): 1022. http://dx.doi.org/10.3390/cells10051022.

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Exercise training promotes muscle adaptation and remodelling by balancing the processes of anabolism and catabolism; however, the mechanisms by which exercise delays accelerated muscle wasting are not fully understood. Intramuscular extracellular matrix (ECM) proteins are essential to tissue structure and function, as they create a responsive environment for the survival and repair of the muscle fibres. However, their role in muscle adaptation is underappreciated and underinvestigated. The PubMed, COCHRANE, Scopus and CIHNAL databases were systematically searched from inception until February 2021. The inclusion criteria were on ECM adaptation after exercise training in healthy adult population. Evidence from 21 studies on 402 participants demonstrates that exercise training induces muscle remodelling, and this is accompanied by ECM adaptation. All types of exercise interventions promoted a widespread increase in collagens, glycoproteins and proteoglycans ECM transcriptomes in younger and older participants. The ECM controlling mechanisms highlighted here were concerned with myogenic and angiogenic processes during muscle adaptation and remodelling. Further research identifying the mechanisms underlying the link between ECMs and muscle adaptation will support the discovery of novel therapeutic targets and the development of personalised exercise training medicine.
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Tomlinson, Owen William, Zoe L. Saynor, Daniel Stevens, Joe Antoun, Don S. Urquhart, and Craig Anthony Williams. "Survey of exercise testing and training in cystic fibrosis clinics in the UK: a decade of progress." BMJ Open 13, no. 4 (April 2023): e072461. http://dx.doi.org/10.1136/bmjopen-2023-072461.

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ObjectivesRegular exercise testing is recommended for people with cystic fibrosis (pwCF), as is the provision and regular review of exercise training programmes. A previous survey on exercise testing and training for pwCF in the UK was conducted over a decade ago. With the landscape of CF changing considerably during this time, this survey aimed to evaluate UK-based exercise testing and training practices for pwCF a decade on.DesignCross-sectional, online survey.ParticipantsA survey was distributed electronically to UK CF clinics and completed by the individual primarily responsible for exercise services. Descriptive statistics and qualitative analyses were undertaken.ResultsIn total, 31 CF centres participated, representing ~50% of UK specialist clinics. Of these, 94% reported using exercise testing, 48% of which primarily use cardiopulmonary exercise testing. Exercise testing mostly occurs at annual review (93%) and is most often conducted by physiotherapists (62%). A wide variation in protocols, exercise modalities, normative reference values and cut-offs for exercise-induced desaturation are currently used. All centres reportedly discuss exercise training with pwCF; 94% at every clinic appointment. However, only 52% of centres reportedly use exercise testing to inform individualised exercise training. Physiotherapists typically lead discussions around exercise training (74%).ConclusionsThese data demonstrate that the majority of respondent centres in the UK now offer some exercise testing and training advice for pwCF, representing a marked improvement over the past decade. However, continued efforts are now needed to standardise exercise practices, particularly regarding field testing practices and the translation of test results into personalised training programmes for pwCF.
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Jin, Zheyu, and HAMDAN MOHD ALI. "A Discussion on Adding Personalized Strength Training to College Students' Physical Health in Physical Education Courses." Journal of Education and Educational Research 11, no. 1 (October 28, 2024): 62–65. http://dx.doi.org/10.54097/0xnwgt89.

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This paper provides an in-depth discussion of the effects of incorporating standardised individualised strength training in the college physical education curriculum on the physiological health of college students. With the popularisation of higher education and the intensification of employment competition, the physical and mental health of college students has attracted much attention. As a key part of the physical education curriculum, its reform and innovation are particularly important. Standardised personalised strength training effectively improves the muscular strength and endurance of college students and strengthens their physical fitness through the development of targeted training plans and the full consideration of students' individual differences. This kind of training not only promotes the improvement of cardiorespiratory function of college students and reduces the risk of cardiovascular disease, but also regulates their psychological state and enhances their overall sense of well-being through exercise. In addition, personalised strength training also cultivated students' teamwork and self-challenge spirit, laying a solid foundation for their all-round development. Therefore, the incorporation of standardised personalised strength training in the college physical education curriculum has a positive impact on the physiological health of college students and is worthy of further promotion and application.
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Sarquella-Brugada, Georgia, Estefanía Martínez-Barrios, Sergi Cesar, Rocío Toro, José Cruzalegui, Andrea Greco, Nuria Díez-Escuté, et al. "A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations." BMJ Open Sport & Exercise Medicine 10, no. 3 (July 2024): e001852. http://dx.doi.org/10.1136/bmjsem-2023-001852.

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Sudden cardiac death is a rare but socially devastating event, especially if occurs in young people. Usually, this unexpected lethal event occurs during or just after exercise. One of the leading causes of sudden cardiac death is inherited arrhythmogenic syndromes, a group of genetic entities characterised by incomplete penetrance and variable expressivity. Exercise can be the trigger for malignant arrhythmias and even syncope in population with a genetic predisposition, being sudden cardiac death as the first symptom. Due to genetic origin, family members must be clinically assessed and genetically analysed after diagnosis or suspected diagnosis of a cardiac channelopathy. Early identification and adoption of personalised preventive measures is crucial to reduce risk of arrhythmias and avoid new lethal episodes. Despite exercise being recommended by the global population due to its beneficial effects on health, particular recommendations for these patients should be adopted considering the sport practised, level of demand, age, gender, arrhythmogenic syndrome diagnosed but also genetic diagnosis. Our review focuses on the role of genetic background in sudden cardiac death during exercise in child and young population.
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Rodriguez, K. Jungbluth, J. Coombes, and S. Keating. "Personalised exercise as medicine for type 2 diabetes: finding the ‘sweet spot’ for glycaemic control." Journal of Science and Medicine in Sport 22 (October 2019): S88—S89. http://dx.doi.org/10.1016/j.jsams.2019.08.103.

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Evans, R. A., J. Manifield, S. A. Simpson, C. Greaves, S. Barber, G. Waheed, G. Barwell, et al. "Personalised Exercise-rehabilitation for People With Multiple Long-term Conditions (PERFORM): A Randomised Feasibility Study." American Journal of Respiratory and Critical Care Medicine 211, Abstracts (May 2025): A1041. https://doi.org/10.1164/ajrccm.2025.211.abstracts.a1041.

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Kostick, Ellie, Victoria Hurwitz, Jessica La, Charlotte Robinson, Aeron Suarez, Sarah Hedges, Renata Fukuthi, et al. "WHAT ROLE CAN A PERSONAL TRAINER PLAY IN IMPROVING QUALITY OF LIFE THROUGHOUT ONCOLOGY TREATMENT FOR PEOPLE WITH A BRAIN TUMOUR." Neuro-Oncology 25, Supplement_3 (September 16, 2023): iii22. http://dx.doi.org/10.1093/neuonc/noad147.094.

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Abstract AIMS Review of a single person case study to establish if a personal trainer (PT) could help build a personalised pro- gramme for people with brain tumours going through oncology treatment. The aim being to help manage resilience both physically and psychologically through treatment and improve quality of life. METHOD A young person who has completed radiotherapy and chemotherapy after surgical debulking of a brain tumour was contacted. He worked as a PT before diagnosis and continued throughout treatment. He gradually increased his exercise tolerance and tailored exercises to different days of the treatment cycle to match his needs. He managed his fatigue and gradually built his exercise tolerance up back to baseline and continue with treatment. RESULTS This patient created a ‘patient guide’ with suggested exercises from his unique perspective as a person who has been through treatment and as a PT. CONCLUSIONS This guide has not yet been trialled with the rest of the patient population. The hope is that this will be used to guide further research in this field and may lead to the implementation of a permeant PT member of staff to the oncology service. In his words ‘this is just an example of my journey and how I stumbled my way through the diffculty of a cancer diagnosis and subsequent treatment. If you can take something away and apply it to your own situation then that’s brilliant’, ‘each day is a testament to how well you’re doing’
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McGrath, Deirdre, Peter O’Halloran, Gillian Prue, Malcolm Brown, Joanne Millar, Adrina O’Donnell, Lisa McWilliams, Claire Murphy, Gwyneth Hinds, and Joanne Reid. "Exercise Interventions for Women with Ovarian Cancer: A Realist Review." Healthcare 10, no. 4 (April 13, 2022): 720. http://dx.doi.org/10.3390/healthcare10040720.

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Background: Despite evidence indicating the benefits of exercise interventions for women with ovarian cancer both during and following treatment, uptake is poor. There is limited research exploring the implementation of such interventions for this cohort of women. The purpose of this review was to identify implementation theories in relation to exercise interventions for women with stages I–IV ovarian cancer, both during and following treatment; to explain positive and negative contextual factors, which may help or hinder implementation; and to develop a theory on how exercise interventions for women with ovarian cancer may be implemented. Methods: This realist review sourced literature from five electronic databases: CINAHL plus, Medline, Embase, PsycINFO and Google Scholar. Methodological rigour was assessed using the relevant critical appraisal skills programme tools. Results: Nine papers were included. Two intervention stages were identified: first, optimising uptake by providing education to patients on the benefits of exercise, approaching patients when symptoms are adequately managed and offering a personalised exercise programme; second, adherence and retention are influenced by the provision of an “autoregulated” exercise programme with additional supportive infrastructure, individualised goal setting and symptom management support where required. Conclusion: Women with ovarian cancer are reluctant to engage in exercise interventions, despite the supporting evidence in terms of positive clinical outcomes. This realist review elucidates underlying mechanisms and important contextual factors that will support and guide the implementation of exercise interventions for this cohort of women.
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Nikoletou, Dimitra, Irina Chis Ster, Carmen Y. Lech, Iain S. MacNaughton, Felix Chua, Raminder Aul, and Paul W. Jones. "Comparison of high-intensity interval training versus moderate-intensity continuous training in pulmonary rehabilitation for interstitial lung disease: a randomised controlled pilot feasibility trial." BMJ Open 13, no. 8 (August 2023): e066609. http://dx.doi.org/10.1136/bmjopen-2022-066609.

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ObjectivesThis study aimed to investigate the feasibility and efficacy of high-intensity interval training (HIIT) compared with moderate-intensity continuous training (MICT) in pulmonary rehabilitation (PR) for people with interstitial lung disease (ILD).DesignSingle-centre, randomised controlled feasibility, pilot trial.SettingPatients were recruited from the chest clinic of a tertiary ILD centre and attended circuit-based PR in the hospital’s gym, followed by a personalised 6-month community programme.Participants58 patients, stratified per ILD type, were randomised into two groups: 33 to HIIT (18 males:15 females) (mean age (SD): 70.2 (11.4) years) and 25 to the MICT exercise mode (14 males:11 females) (mean age (SD): 69.8 (10.8) years).Interventions8-week, twice weekly, circuit-based PR programme of exercise and education, followed by a personalised 6-month community exercise programme.Outcome measuresFeasibility outcomes included staff-to-patient ratio and dropout rates per group. Primary outcome was the 6 min walk distance (6MWD). Secondary outcomes included the sniff nasal pressure, mouth inspiratory and expiratory pressures, handgrip and quadriceps strength and health status. Random-effects models were used to evaluate average variation in outcomes through time across the two groups.ResultsThe 6MWD peaked earlier with HIIT compared with MICT (at 4 months vs 5 months) but values were lower at peak (mean (95% CI): 26.3 m (3.5 to 49.1) vs 51.6 m (29.2 to 73.9)) and declined faster at 6 months post-PR. Secondary outcomes showed similar faster but smaller improvements with HIIT over MICT and more consistent maintenance 6 months post-PR with MICT than HIIT.ConclusionsHIIT is feasible in circuit-based ILD PR programmes and provides quick improvements but requires closer supervision of training and resources than MICT and benefits may be less well sustained. This would make it a less attractive option for clinical PR programmes. A definitive, multicentre randomised controlled trial is required to address the role of HIIT in ILD.Trial registration numberISRCTN55846300.
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Guazzi, Marco. "Assessment for Exercise Prescription in Heart Failure." Cardiac Failure Review 1, no. 1 (2015): 46. http://dx.doi.org/10.15420/cfr.2015.01.01.46.

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Exercise training (ET) is a Guidelines Class 1A level of evidence adjunct therapy for heart failure (HF) with reduced ejection fraction treatment. As yet less certain is the role of ET for HF with preserved ejection fraction. Different ET types (endurance and resistance) and levels of intensity or domains (light, light-to-moderate and high-to-moderate) are used for ET programmes in patients with cardiac failure. Assessment of ET prescription can be performed through indirect (heart rate reserve) or direct metabolic measures (VO2 reserve, ventilatory threshold) with the most precise methodology based on the analysis of VO2 kinetics during constant work rate protocols of different workloads. The goals of assessing the effects of exercise prescription on functional capacity are traditionally represented by changes in VO2 during peak exercise by cardiopulmonary exercise testing (CPET). Nonetheless, the specific evaluation of how ET may favourably affect the abnormal patterns of VO2 linearity for work rate increase and the effects on ventilation seem important adjunctive parameters to be evaluated and monitored. Although a minority, some HF patients may not respond to ET programmes. This specific phenotype, once appropriately identified, needs a different approach and – intriguingly – should be switched to a higher ET intensity domain to yield the most comprehensive benefits from a personalised ET intervention.
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Freeman, Anna, Doriana Cellura, Magdalena Minnion, Bernadette O. Fernandez, Cosma Mirella Spalluto, Denny Levett, Andrew Bates, et al. "Exercise Training Induces a Shift in Extracellular Redox Status with Alterations in the Pulmonary and Systemic Redox Landscape in Asthma." Antioxidants 10, no. 12 (November 30, 2021): 1926. http://dx.doi.org/10.3390/antiox10121926.

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Redox dysregulation and oxidative stress have been implicated in asthma pathogenesis. Exercise interventions improve symptoms and reduce inflammation in asthma patients, but the underlying mechanisms remain unclear. We hypothesized that a personalised exercise intervention would improve asthma control by reducing lung inflammation through modulation of local and systemic reactive species interactions, thereby increasing antioxidant capacity. We combined deep redox metabolomic profiling with clinical assessment in an exploratory cohort of six female patients with symptomatic asthma and studied their responses to a metabolically targeted exercise intervention over 12 weeks. Plasma antioxidant capacity and circulating nitrite levels increased following the intervention (p = 0.028) and lowered the ratio of reduced to oxidised glutathione (p = 0.029); this was accompanied by improvements in physical fitness (p = 0.046), symptoms scores (p = 0.020), quality of life (p = 0.046), lung function (p = 0.028), airway hyperreactivity (p = 0.043), and eosinophilic inflammation (p = 0.007). Increased physical fitness correlated with improved plasma antioxidant capacity (p = 0.019), peak oxygen uptake and nitrite changes (p = 0.005), the latter also associated with reductions in peripheral blood eosinophil counts (p = 0.038). Thus, increases in “redox resilience” may underpin the clinical benefits of exercise in asthma. An improved understanding of exercise-induced alterations in redox regulation offers opportunities for greater treatment personalisation and identification of new treatment targets.
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Kok, Annemieke, Ellen Passchier, Anne M. May, Harriët Jager-Wittenaar, Cindy Veenhof, Remco de Bree, Martijn M. Stuiver, and Caroline M. Speksnijder. "Expectations and Experiences of Participating in a Supervised and Home-Based Physical Exercise Intervention in Patients with Head and Neck Cancer during Chemoradiotherapy: A Qualitative Study." Current Oncology 31, no. 2 (February 4, 2024): 885–99. http://dx.doi.org/10.3390/curroncol31020066.

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(1) Background: Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with severe toxicity resulting in fatigue and weight loss, including loss of skeletal muscle mass. Exercise interventions might positively affect physical fitness and quality of life. Sufficient adherence and compliance rates are necessary for optimal effects. This study aimed to gain insight into expectations and experiences and factors influencing adherence, retention and compliance of HNC patients participating in exercise intervention during CRT. (2) Methods: Consecutive participants were invited for semi-structured interviews, conducted pre- and post-intervention. A deductive approach was used to identify themes and factors influencing adherence, retention and compliance. (3) Results: Thematic saturation was reached after interviewing 14 patients pre-intervention. Five themes were identified: planning and time management, treatment toxicity, motivation to exercise, exercise intervention and supervision by a physiotherapist. The intensity of the treatment schedule and treatment toxicity were important barriers. Facilitators mentioned were physical and emotional benefits, social support as well as the simplicity and home-based setting of the intervention. (4) Conclusions: A personalised approach, considering the individual facilitators and barriers of HNC patients, is important to increase adherence, retention and compliance to exercise intervention and to reap the optimal effects of the program.
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Allcock, Sarah J., and Julie A. Hulme. "Learning styles in the classroom: Educational benefit or planning exercise?" Psychology Teaching Review 16, no. 2 (2010): 67–79. http://dx.doi.org/10.53841/bpsptr.2010.16.2.67.

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Differentiation of teaching is encouraged to accommodate student diversity. This study investigated whether using learning styles as a basis for differentiation improved A–level student performance, compared to differentiation on the basis of academic ability.Matched classes of A–level psychology students participated. In one class, learning activities were differentiated by academic ability; in the other class, learning activities were differentiated by learning style for nine weeks, followed by a further class test. Student understanding of learning styles was also investigated.Both classes significantly improved from baseline to final test, but there was no significant difference in improvement between the two groups, and indeed a slight trend for more improvement following differentiation by ability. Further research into personalised learning is required, and suggestions are made for a student–focussed intervention to enable students to better understand and to employ their own learning styles as a tool for independent study.
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Gilanyi, Mr Yannick, Ms Brishna Shah, Dr Aidan Cashin, Dr Mitchell T. Gibbs, Ms Jessica Bellamy, Dr Richard Day, James H. McAuley, and Matthew D. Jones. "BARRIERS AND ENABLERS TO EXERCISE ADHERENCE IN PEOPLE WITH CHRONIC LOW BACK PAIN: A SYSTEMATIC REVIEW OF QUALITATIVE EVIDENCE." Journal of Clinical Exercise Physiology 13, s2 (May 1, 2024): 412. http://dx.doi.org/10.31189/2165-7629-13-s2.412.

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INTRODUCTION Exercise is a first line treatment for chronic low back pain, reducing pain and disability in the short-term. However, exercise benefits decrease over time, with a lack of long-term exercise adherence a potential reason for this. This study aimed to synthesize the perceptions and beliefs of individuals with chronic low back pain and identify their barriers and enablers to exercise adherence. METHODS We searched CENTRAL, EMBASE, CINAHL, SPORTDiscus, PubMed, PsycINFO, CINAHL, and Scopus databases from inception to 28th February 2023 for qualitative studies that explored the factors influencing exercise adherence for people with chronic low back pain. A hybrid approach combining inductive analysis using thematic synthesis and a deductive analysis, which included the Theoretical Domains Framework of behaviour change was used to analyse data. We assessed methodological quality using the Critical Appraisal Skills Programme checklist and the level of confidence of the themes found using the Confidence in the Evidence from Reviews of Qualitative Studies (GRADE-CERQual). RESULTS Twenty-three papers (n=21 studies) were included (n=478 participants). Four main themes impacted exercise adherence: 1) exercise, pain, and the body, 2) psychological factors, 3) social factors and 4) external factors. These themes contained 16 subthemes that were predominantly both barriers and enablers to exercise adherence. There was moderate to high confidence across the findings. CONCLUSION Our analysis found that individual’s experiences of barriers and enablers were most appropriately represented across a spectrum, where influencing factors could be a barrier or enabler to exercise adherence. Barriers and enablers were also found to be specific to pre-exercise, during exercise and post-exercise situations. This may lead to an improved and targeted approach to increasing exercise adherence. Further research is required to develop interventions that can use these findings for a more personalised and patient centred approach to treatment.
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PETTIGREW, SIMONE, ELISSA BURTON, KAELA FARRIER, ANNE-MARIE HILL, LIZ BAINBRIDGE, PHIL AIREY, GILL LEWIN, and KEITH D. HILL. "Encouraging older people to engage in resistance training: a multi-stakeholder perspective." Ageing and Society 39, no. 8 (April 10, 2018): 1806–25. http://dx.doi.org/10.1017/s0144686x1800034x.

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AbstractResistance training is an important aspect of healthy ageing, yet participation rates are especially low among older people. Strategies are needed to ensure resistance training programmes are attractive to and appropriate for this target group. To inform the development of such strategies, individual interviews (N = 42) and focus groups (four groups, N = 37) were conducted with 79 Western Australians representing four stakeholder groups: instructors who deliver resistance training programmes to older people, health practitioners, policy makers and seniors. Results indicate that the need for personalised attention in the establishment and maintenance phases of a resistance training programme can constitute both a positive and negative aspect of older people's experiences. The negative aspects were identified as a series of tensions between the need for personalised attention and (a) the desire to participate in physical activity within social groups, (b) a preference for activity variation, (c) a dislike for large centres where personalised guidance is often available yet the surroundings can be considered unappealing, (d) cost issues and (e) the need for flexibility in attendance. Recommended strategies for overcoming these tensions include disseminating information about the benefits of resistance training in later life to increase motivation to participate, identifying additional methods of integrating resistance training into group exercise formats, making gyms more attractive to older people and providing non-gym alternatives for resistance training.
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