To see the other types of publications on this topic, follow the link: Personality disorders – Testing.
Journal articles on the topic 'Personality disorders – Testing'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Personality disorders – Testing.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Roy, Nelson. "Personality and Voice Disorders." Perspectives on Voice and Voice Disorders 21, no. 1 (March 2011): 17–23. http://dx.doi.org/10.1044/vvd21.1.17.
Full textAbstract:
It has been argued that personality, emotions, and psychological problems contribute to or are primary causes of voice disorders, and that voice disorders in turn create psychological problems and personality effects. This article provides an overview of recent concepts in personality and trait structure, briefly summarizes the “Trait Theory” which explains how personality may contribute to the development of primary muscle tension dysphonia and vocal nodules, reviews research aimed at testing the Trait Theory, and discusses clinical implications related to recognizing personality as a factor in the development, maintenance, and treatment of primary muscle tension dysphonia and vocal nodules.
2
Adshead, Gwen, and Jaydip Sarkar. "The nature of personality disorder." Advances in Psychiatric Treatment 18, no. 3 (May 2012): 162–72. http://dx.doi.org/10.1192/apt.bp.109.006981.
Full textAbstract:
SummaryThe lack of a medically grounded approach to personality disorder and its management has led to its comparative neglect as a topic by many clinicians in the UK. In this article we present evidence that personality disorders are, like other mental disorders, the social manifestations of a pathological process. This process presents with characteristic clinical features that are developmental in nature. These cause disturbances in arousal, affect and reality testing that have an impact on interpersonal social functioning. Personality disorder may therefore be conceived of primarily as a socioemotional disability, not dissimilar to Axis I conditions.
3
Schiavone, Francesca L., Margaret C. McKinnon, and Ruth A. Lanius. "Psychotic-Like Symptoms and the Temporal Lobe in Trauma-Related Disorders: Diagnosis, Treatment, and Assessment of Potential Malingering." Chronic Stress 2 (January 2018): 247054701879704. http://dx.doi.org/10.1177/2470547018797046.
Full textAbstract:
Objective To overview the phenomenology, etiology, assessment, and treatment of psychotic-like symptoms in trauma-related disorders focusing on the proposed role of temporal lobe dysfunction. Method We describe the literature pertaining to (i) psychotic-like symptoms and temporal lobe dysfunction in trauma-related disorders and (ii) psychological testing profiles in trauma-related disorders. We define trauma-related disorders as borderline personality disorder, post-traumatic stress disorder, and the dissociative disorders. Our search terms were dissociative disorders, temporal lobe, trauma, post-traumatic stress disorder, borderline personality disorder, psychosis, and malingering. Results Trauma-related psychotic-like symptoms are common and can differ in phenomenology from primary psychotic symptoms. Hallucinations consist of auditory and nonauditory content that may or may not relate to traumatic content. Child voices are highly suggestive of complex dissociative disorders. Critically, not only do these symptoms resemble those seen in temporal lobe epilepsy, but the temporal lobe is implicated in trauma-related disorders, thus providing a plausible neurobiological explanation. Despite such evidence, these symptoms are frequently considered atypical and misdiagnosed. Indeed, common structured psychological assessment tools categorize these symptoms as possible indicators of invalid testing profiles. Conclusion Psychotic-like symptoms are common in trauma-related disorders, may be related to temporal lobe dysfunction, and are frequently misinterpreted. This may lead to ineffective treatment and inappropriate determinations of malingering in the forensic system.
4
Nanda, Yoga Aditama Ika, and Bety Wulan Sari. "NAIVE BAYES ALGORITHM IMPLEMENTATION TO DETECT HUMAN PERSONALITY DISORDERS." Jurnal Techno Nusa Mandiri 17, no. 1 (March 5, 2020): 9–16. http://dx.doi.org/10.33480/techno.v17i1.1239.
Full textAbstract:
We live in a society that still sees problems regarding one's soul and personality as taboo, even though mental health is as important as physical health. A personality disorder itself is a disorder that can be seen from behavior, mindset, and attitude, which brings difficulties to life. Based on this problem, this study applies the method of Naive Bayes classifier as early detection of human personality disorders. Using a data set of 130 correspondences from the AMIKOM university scope with the age limit of 18-25 years and identified personality disorders is a borderline type disorder. The data obtained was 94 with undiagnosed classes and 36 with undiagnosed classes, with the research variables in the form of questionnaire questions as many as 13 questions. The testing process is done with 10 fold and 5 fold cross-validation, and confusion matrix with the results in the form of accurate 10 folds superior with a value of 88.8% compared to 5 folds that is 88.2%, for precision 10 folds superior with 88.7%, but for 5 fold recall superior with 88.3%, while the final results of these two performances in F1-Score, produce the same value, which is 86.1%.
5
Melson-Silimon, Arturia, Alexandra M. Harris, Elizabeth L. Shoenfelt, Joshua D. Miller, and Nathan T. Carter. "Personality testing and the Americans With Disabilities Act: Cause for concern as normal and abnormal personality models are integrated." Industrial and Organizational Psychology 12, no. 2 (June 2019): 119–32. http://dx.doi.org/10.1017/iop.2018.156.
Full textAbstract:
AbstractApplied psychologists commonly use personality tests in employee selection systems because of their advantages regarding incremental criterion-related validity and less adverse impact relative to cognitive ability tests. Although personality tests have seen limited legal challenges in the past, we posit that the use of personality tests might see increased challenges under the Americans with Disabilities Act (ADA) and the ADA Amendments Act (ADAAA) due to emerging evidence that normative personality and personality disorders belong to common continua. This article aims to begin a discussion and offer initial insight regarding the possible implications of this research for personality testing under the ADA. We review past case law, scholarship in employment law, Equal Employment Opportunity Commission (EEOC) guidance regarding “medical examinations,” and recent literature from various psychology disciplines—including clinical, neuropsychology, and applied personality psychology—regarding the relationship between normative personality and personality disorders. More importantly, we review suggestions proposing the five-factor model (FFM) be used to diagnose personality disorders (PDs) and recent changes in theDiagnostic and Statistical Manual of Mental Disorders(DSM). Our review suggests that as scientific understanding of personality progresses, practitioners will need to exercise evermore caution when choosing personality measures for use in selection systems. We conclude with six recommendations for applied psychologists when developing or choosing personality measures.
6
Nielsen, Per, and Steffen Røjskjær. "Article." Nordic Studies on Alcohol and Drugs 19, no. 2 (April 2002): 123–37. http://dx.doi.org/10.1177/145507250201900202.
Full textAbstract:
Per Nielsen & Steffen R⊘jskjær: Dual disorder among alcohol addicted inpatient clients This study examines the prevalence and subtypes of personality disorders among alcohol-addicted inpatients, and the impact on drop out during treatment. The study is the first phase of a prospective study of dual disorder clients (alcohol addiction and personality disorder). Subjects were 104 clients with severe alcohol problems consecutively admitted to a Danish addiction treatment center (Ring-gaarden) applying a cognitive frame of reference. Each client was tested during the first two weeks using the Millon Clinical Multiaxial Inventory (MCMI II-I). According to the psychological testing seven out of eight subjects manifested at least one personality disorder – and 65% of the clients had two or more personality disorders. Anti-social and/or passive-aggressive personality disorder was present in more than 50% of the subjects. Borderline personality disorder was found in about 30%. More than half of the subjects had elevated scores of anxiety and/or dysthymia. Cluster analysis revealed four distinct subtypes of clients: a. no/slight personality disorder, b. “avoidant/dependent”, c. “antisocial/narcissistic” and d. “borderline”. The drop-out rate was significantly higher for the “borderline” group than for the other three. The implications for treatment are discussed.
7
Mudholkar, S. "Neurocognitive Basis of Impulsivity in Personality Disorders." European Psychiatry 24, S1 (January 2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70573-5.
Full textAbstract:
Aim:1.Whether patients with personality disorders of borderline and antisocial type have a specific pattern of neurocognitive deficits.2.Whether impulsivity measured with clinical rating scales is related with performance on neuropsychological tests of risk taking which is sensitive to ventrofrontal cortex lesions.Method:20 patients and their age, sex and IQ matched controls participated in the study. Each patient and control was administered validated clinical rating scales in order to:1.Ascertain the diagnosis with respect to DSM-IV criteria (Structured Clinical Interview for DSM: Personality Disorder.2.Obtain a measure of clinical impulsivity (Barratt Impulsiveness scale).3.Ascertain the presence of heritable personality traits (Dimensional Aspects Of Personality Pathology Disorder-Basic Questionnaire).4.Exclude other major psychiatric disorders (Clinical Psychopathology Rating Scale).They were administered National Adult Reading Test (NART) to estimate IQ.A battery of neuropsychological tests of memory and executive function specifically sensitive to frontal (dorsal or ventral) or temporal lobe damage were administered from Cambridge Automated Neuropsychological Test battery (CANTAB).Results:On Neuropsychological testing patients fared poorly on tests sensitive to planning and risk taking compared to controls. Patients had high mean scores on Barratt impulsiveness scale. The high scores were associated with performance on Tower Of London, Bechara test and paired associated learning. Impulsivity was associated with anxiousness and rejection traits of DAPP-BQ. There was a co-relation between some basic dispositional traits of DAPP-BQ with performance on Bechara, Gambling and Paired Associated Learning tests.Conclusion:Personality disordered patients show broad range of neurocognitive deficits on test s sensitive to frontal cortex.
8
Mudholkar, S. "Neurocognitive Basis of Impulsivity in Personality Disorders." European Psychiatry 24, S1 (January 2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)71315-x.
Full textAbstract:
Aim:1.Whether patients with personality disorders of borderline and antisocial type have a specific pattern of neurocognitive deficits.2.Whether impulsivity measured with clinical rating scales is related with performance on neuropsychological tests of risk taking which is sensitive to ventrofrontal cortex lesions.Method:20 patients and their age, sex and IQ matched controls participated in the study. Each patient and control was administered validated clinical rating scales in order to:1.Ascertain the diagnosis with respect to DSM-IV criteria (Structured Clinical Interview for DSM: Personality Disorder.2.Obtain a measure of clinical impulsivity (Barratt Impulsiveness scale).3.Ascertain the presence of heritable personality traits (Dimensional Aspects of Personality Pathology Disorder-Basic Questionnaire).4.Exclude other major psychiatric disorders (Clinical Psychopathology Rating Scale).They were administered National Adult Reading Test (NART) to estimate IQ.A battery of neuropsychological tests of memory and executive function specifically sensitive to frontal (dorsal or ventral) or temporal lobe damage were administered from Cambridge Automated Neuropsychological Test battery (CANTAB).Results:On Neuropsychological testing patients fared poorly on tests sensitive to planning and risk taking compared to controls. Patients had high mean scores on Barratt impulsiveness scale. the high scores were associated with performance on Tower of London, Bechara test and paired associated learning. Impulsivity was associated with anxiousness and rejection traits of DAPP-BQ. There was a co-relation between some basic dispositional traits of DAPP-BQ with performance on Bechara, Gambling and Paired Associated Learning tests.Conclusion:Personality disordered patients show broad range of neurocognitive deficits on test s sensitive to frontal cortex.
9
Besteiro-González, J. L., S. Lemos-Giráldez, and J. Muñiz. "Neuropsychological, Psychophysiological, and Personality Assessment of DSM-IV Clusters of Personality Disorders." European Journal of Psychological Assessment 20, no. 2 (January 2004): 99–105. http://dx.doi.org/10.1027/1015-5759.20.2.99.
Full textAbstract:
Testing the construct validity of the three DSM-IV cluster groupings of personality disorders, in terms of neuropsychological, psychophysiological, and personality traits measures, was the purpose of this study. The results hardly confirm significant differences between B and C cluster groups in their neuropsychological functioning, but, instead, suggest that Cluster A could have some empirical validity based on executive prefrontal deficits (concept formation and sustained attention tasks) and clinical features. Similarly, no consistent differences among groups emerge when psychophysiological measures are compared. With regard to the Big-Five personality dimensions, the results also indicate that clusters may be more heterogeneous than the DSM-IV suggests. It appears, therefore, that the categorical division of DSM personality disorders into three discrete clusters may not be empirically justified.
10
McGlashan, Thomas H. "Testing DSM-III Symptom Criteria for Schizotypal and Borderline Personality Disorders." Archives of General Psychiatry 44, no. 2 (February 1, 1987): 143. http://dx.doi.org/10.1001/archpsyc.1987.01800140045007.
Full text
11
Paris, Joel. "Social Risk Factors for Borderline Personality Disorder: A Review and Hypothesis*." Canadian Journal of Psychiatry 37, no. 7 (September 1992): 510–15. http://dx.doi.org/10.1177/070674379203700708.
Full textAbstract:
A number of behaviours associated with borderline personality disorder (including attempted suicide, suicide, substance abuse, and antisocial behaviour) are on the increase among the young. The common factor in these disorders is impulsiveness. Evidence is reviewed suggesting that social disintegration reduces the threshold of impulsive behaviours. It is proposed that this is the mechanism through which social risk factors effect the prevalence and morbidity of borderline personality. A number of ways of testing this hypothesis are suggested.
12
Soleliza Jones, Anna Hendri, and Cicin Hardiyanti. "Case Based Reasoning using K-Nearest Neighbor with Euclidean Distance for Early Diagnosis of Personality Disorder." IJISTECH (International Journal of Information System & Technology) 5, no. 1 (June 30, 2021): 23. http://dx.doi.org/10.30645/ijistech.v5i1.111.
Full textAbstract:
A personality disorder is a condition of a person with an extreme personality that causes the sufferer to have unhealthy and different thoughts patterns and behavior from other people. The personality disorders discussed in this study consisted of 110 diseases with 300 case data and 68 symptoms. Based on Basic Health Research (Riskesdas) 2018 data, it shows that more than 19 million people aged 15 years and over were affected by mental-emotional disorders. Data from the Statistics Indonesia in 2019 that the population of Indonesia is around 265 million people, while according to the Indonesian Clinical Psychologist Association, the number of verified professional psychologists is 1,599 clinical psychologists out of a total membership of 2,078 as of January 2019. However, this figure does not meet the standards of the World Health Organization (WHO), which is that psychologists serve 30 thousand people. This shows that Indonesia still lacks around 28,970 psychologists. The unequal distribution of professional psychologists has made psychologists need a long time to provide a diagnosis because of the number of patients being inversely proportional to the availability of psychologists in Indonesia. Moreover, there is not enough patient knowledge about the symptoms they feel. This study aims to produce a system for diagnosing personality disorders. This study is a case based reasoning to solve problems that have occurred in previous cases using K-Nearest Neighbor to classify data based on the closest distance using the calculation of the Euclidean Distance. Algorithm testing for the system used the Confusion Matrix test. Based on the results of testing data in the 60 case data using K-nearest Neighbor and the calculation of the Euclidean Distance with a score of K=3, it is known that 60 data have 100% similarity to cases with a personality disorder. Meanwhile, testing new cases with 10 case data that were not in the knowledge base was also conducted showing that 9 cases had 100% similarity to the previous case, while another case had 90% similarity to the previous case.
13
Links, Paul S. "Developing Effective Services for Patients with Personality Disorders." Canadian Journal of Psychiatry 43, no. 3 (April 1998): 251–59. http://dx.doi.org/10.1177/070674379804300303.
Full textAbstract:
Objective: This review focused on empirical research that addressed the effectiveness of service models for the care of patients with personality disorders. Method: Services discussed included those delivering acute care, such as crisis and emergency services and acute psychiatric hospitalization; continuing care, such as outpatient services, day hospital treatment, and assertive community treatment programs; and other community programming, such as integrated treatment for comorbid substance abuse and psychoeducational interventions for families of patients with personality disorders. The review focused on studies that included patients with personality disorders, and it measured outcomes relevant to patients with personality disorders. Evidence from randomized controlled trials was highlighted. Results: Few systematic studies of acute services were available. Community programming can decrease the risk of suicide attempts and reliance on inpatient admissions. Services must develop methods of ensuring compliance with treatment. Assertive community treatment for Axis II patients should be developed, implemented, and tested. Comprehensive programming for patients with personality disorders must include integrated treatment for substance abuse and family psychoeducational programs. Conclusion: Promising new models of care for patients with personality disorders are ready for testing and wider application.
14
Fairley, Michael, Roderick C. Jones, Brian E. McGuire, and Janine Stevenson. "Multiple Personality Disorder in an Intellectually Disabled Man: A Case Report." Australian & New Zealand Journal of Psychiatry 29, no. 1 (March 1995): 146–49. http://dx.doi.org/10.3109/00048679509075904.
Full textAbstract:
The case of a young man with the dual diagnoses of severe intellectual handicap (IQ 30 and mental age 4 years) and Multiple Personality Disorder is presented. The intellectual handicap is probably due to hypoxia in infancy and the Multiple Personality Disorder follows prolonged physical and sexual abuse. The patient frequently switches between any of nine discrete but incompletely formed identities. Although some personalities seem more capable than others, all have similar levels of disability on testing. The diagnosis of psychiatric disorders coexistent with the intellectual handicap is hindered by the difficulty in separating psychiatric phenomena from the behavioural disturbances associated with the disability. Differential diagnosis and management are discussed.
15
ARMSTRONG, JUDITH G., and RICHARD J. LOEWENSTEIN. "Characteristics of Patients with Multiple Personality and Dissociative Disorders on Psychological Testing." Journal of Nervous and Mental Disease 178, no. 7 (July 1990): 448–54. http://dx.doi.org/10.1097/00005053-199007000-00006.
Full text
16
Mordas, Ekaterina Sergeevna, and Yana Vladimirovna Berseneva. "Personality traits of women with psychogenic infertility (on different levels of organization of individuality)." Психология и Психотехника, no. 3 (March 2020): 69–83. http://dx.doi.org/10.7256/2454-0722.2020.3.30428.
Full textAbstract:
This article reviews the results of research dedicated to personality characteristics of women struggling with psychogenic infertility (on different levels of organization of individuality: physical, affective and behavioral). It is assumed that all levels of organization of individuality are interrelated, which allows observing a holistic picture of personality of women involved in the study. The goal consists in examination of personality traits of women with reproductive disorders on physical, personal and social levels of the organization of individuality. The subject of this research is the psychological peculiarities, coping strategies, and psychological defenses of women with reproductive disorders on different levels of organization of individuality. The following methods were applied: empirical, such as testing and quantitative methods (charting); statistical, such as correlation analysis; qualitative methods, such as generalization, systematization, comparison. The scientific novelty lies in studying personality traits of women with reproductive disorders on different levels of the organization of individuality. The conclusion is made that women struggling with psychogenic infertility (comparing to women with no such disorder) are characterized with the following personality traits on different levels of the organization of individuality: 1) on the physical level – distorted perception and dissatisfaction with their body; 2) on the personal (affective) level – high anxiety, both reactive and personal; alexithymia; rigidity; inclination to depressive disorders; 3) on the social (behavioral) level – facing difficult life situations, women with reproductive disorders are not able to take responsibility, and often resort to such defense mechanisms as denial, avoidance, regression and projection.
17
Atadzhykova, Y. A., and S. N. Enikolopov. "Testing K. Patrick Method of Psychopathy Diagnosis in Russian Sample." Психологическая наука и образование 20, no. 4 (2015): 75–85. http://dx.doi.org/10.17759/pse.2015200407.
Full textAbstract:
The article is devoted to the development of a method of diagnosing psychopathy, or antisocial (dissocial) personality disorder. Modern researchers mostly use the methods of experiment, expert assessment, clinical interview or different combinations for personality disorders, including psychopathy. However, nowadays there is a growing need in development of a psychopathy diagnosis method which would be less labour-intensive, less expensive and more objective. One of the recently developed models of psychopathy is Trierarchic conceptualization by C. Patrick, it offers a new way to operationalize and diagnose psychopathy. The authors had tested this method in the Russian population, including both common sample as well as criminal offender sample consisting of individuals that have been suspected, accused or convicted of violent crimes. The subject of the current research is psychopathic traits measured by the tested method. We had carried out statistical and content analyzes of the data. Our study allowed to conclude that tested Russian version of the Triarchic Psychopathy Measure is effective enough to be used for research purposes. However, further research is required in order to render this measure valid to practical use.
18
Pilleron, Sophie, Jean-Pierre Clément, Bébène Ndamba-Bandzouzi, Pascal Mbelesso, Jean-François Dartigues, Pierre-Marie Preux, and Maëlenn Guerchet. "Is dependent personality disorder associated with mild cognitive impairment and dementia in Central Africa? A result from the EPIDEMCA programme." International Psychogeriatrics 27, no. 2 (September 1, 2014): 279–88. http://dx.doi.org/10.1017/s104161021400180x.
Full textAbstract:
ABSTRACTBackground:To date, no studies have examined the relationship between cognitive disorders and personality disorders. Our aim was to investigate the association between dependent personality disorder (DPD) and cognitive disorders in Central Africa.Methods:Between 2011 and 2012, a cross-sectional multicenter population-based study was carried out in rural and urban areas of the Central African Republic (CAR) and the Republic of Congo (ROC). Participants aged ≥65 years were interviewed using the Community Screening Interview for Dementia (CSI-D). Elderly people who performed poorly (CSI-D cognitive tests score or COGSCORE ≤ 24.5/30) were clinically assessed by neurologists and underwent further psychometric testing. The Diagnostic and Statistical Manual of Mental Disorders, 4th Edition and Petersen criteria were required for the diagnosis of dementia and mild cognitive impairment (MCI) respectively. DPD was assessed using the Personality Diagnostic Questionnaire-4+. Socio-demographic, vascular, and psychological factors were also documented. Multivariate multinomial logistic regression models were used to estimate the associations.Results:Of the 2,002 participants screened, 860 and 912 had data for cognitive status and DPD in CAR and ROC respectively. In fully adjusted models, DPD was significantly associated with MCI in ROC (Odds Ratio (OR) = 2.2, 95% CI: 1.0–4.7) and CAR (OR = 2.1, 95% CI: 1.1–4.0) and with dementia only in ROC (OR = 4.8, 95% CI: 2.0–11.7).Conclusions:DPD was associated with cognitive disorders among elderly people in Central Africa. This association should be confirmed in other contexts. This study paves the way for research on the association between personality and cognitive impairment in Africa.
19
Tavares, Hermano, and Valentim Gentil. "Pathological gambling and obsessive-compulsive disorder: towards a spectrum of disorders of volition." Revista Brasileira de Psiquiatria 29, no. 2 (June 2007): 107–17. http://dx.doi.org/10.1590/s1516-44462007000200005.
Full textAbstract:
OBJECTIVE: Pathological gambling is proposed as a participant of an impulsive-compulsive spectrum related to obsessive-compulsive disorder. This study aims to contrast pathological gambling and obsessive-compulsive disorder regarding course, comorbidity, and personality, hence testing the validity of the impulsive-compulsive spectrum. METHOD: 40 pathological gambling and 40 obsessive-compulsive disorder subjects matched to 40 healthy volunteers according to gender, age, and education were assessed with the Temperament Personality Questionnaire and the Barratt Impulsiveness Scale. Psychiatric patients were also assessed for course and comorbidity data. RESULTS: Obsessive-compulsive disorder presented an earlier onset, but the full syndrome took longer to evolve. Pathological gambling had higher comorbidity with substance-related disorders, and obsessive-compulsive disorder higher comorbidity with somatoform disorders. Gamblers scored higher than controls on the sub-factors Impulsiveness, Extravagance, Disorderliness, and Fear of Uncertainty. Obsessive-compulsive patients scored higher than controls on Fear of Uncertai-nty. Impulsiveness, Extravagance, and Disorderliness significantly correlated with the Barratt Impulsiveness Scale total score, Fear of Uncertainty did not. DISCUSSION: The course and comorbidity profiles of pathological gambling resemble an addiction and differ from obsessive-compulsive disorder. Pathological gambling combines impulsive and compulsive traits. Impulsivity and compulsivity should be regarded as orthogonal constructs, and as drives implicated in volition aspects of behavioral syndromes.
20
Mendez, Mario F. "Huntington's Disease: Update and Review of Neuropsychiatric Aspects." International Journal of Psychiatry in Medicine 24, no. 3 (September 1994): 189–208. http://dx.doi.org/10.2190/hu6w-3k7q-nael-xu6k.
Full textAbstract:
Objective: This article presents a general update on Huntington's disease (HD) and reviews the psychiatric and cognitive features of this disorder. Method: HD is discussed in five sections: an introduction and update, the psychiatric aspects, the cognitive aspects, brain-behavior relationships, and the differential diagnosis and management. Results: Recent advancements in HD include the identification of presymptomatic testing methods and HD gene defect, structural and metabolic neuroimaging findings, and a neuropsychological profile. HD is associated with mood disorders, personality changes, irritable and explosive behavior, a schizophrenia-like illness, suicidal behavior, sexuality changes, and specific cognitive deficits. Conclusions: HD results in organic mental disorders from dysfunction of prefrontal-subcortical circuits coursing through the caudate nuclei. The diagnosis of HD is aided by genetic testing, neuroimaging, and neuropsychological testing. Management involves education, genetic counseling, and psychotropic medications. Finally, the future of HD holds promise for the development of rational, neurobiologically-based treatments and genetically engineered therapies.
21
Anderluh, M., K. Tchanturia, S. Rabe-Hesketh, D. Collier, and J. Treasure. "Lifetime course of eating disorders: design and validity testing of a new strategy to define the eating disorders phenotype." Psychological Medicine 39, no. 1 (April 1, 2008): 105–14. http://dx.doi.org/10.1017/s0033291708003292.
Full textAbstract:
BackgroundAetiological studies of eating disorders would benefit from a solution to the problem of instability of eating disorder symptoms. We present an approach to defining an eating disorders phenotype based on the retrospective assessment of lifetime eating disorders symptoms to define a lifetime pattern of illness. We further validate this approach by testing the most common lifetime categories for differences in the prevalence of specific childhood personality traits.MethodNinety-seven females participated in this study, 35 with a current diagnosis of restricting anorexia nervosa, 32 with binge/purging subtype of anorexia nervosa and 30 with bulimia nervosa. Subjects were interviewed by a newly developed EATATE Lifetime Diagnostic Interview for a retrospective assessment of the lifetime course of eating disorders symptoms and childhood traits reflecting obsessive–compulsive personality.ResultsThe data illustrate the extensive instability of the eating disorders diagnosis. Four most common lifetime diagnostic categories were identified that significantly differ in the prevalence of childhood traits. Perfectionism and rigidity were more common in groups with a longer duration of underweight status, longer episodes of severe food restriction, excessive exercising, and shorter duration of binge eating.ConclusionsThe assessment of lifetime symptoms may produce a more accurate definition of the eating disorders phenotype. Obsessive–compulsive traits in childhood may moderate the course producing longer periods of underweight status. These findings may have important implications for nosology, treatment and future aetiological studies of eating disorders.
22
Lilienfeld, Scott O., Ashley L. Watts, Brett Murphy, Thomas H. Costello, Shauna M. Bowes, Sarah Francis Smith, Robert D. Latzman, Nick Haslam, and Kathryn Tabb. "Psychopathy as an Emergent Interpersonal Syndrome: Further Reflections and Future Directions." Journal of Personality Disorders 33, no. 5 (October 2019): 645–52. http://dx.doi.org/10.1521/pedi.2019.33.5.645.
Full textAbstract:
In our article (Lilienfeld et al., 2019), we hypothesized that psychopathy and some other personality disorders are emergent interpersonal syndromes (EISs): interpersonally malignant configurations of distinct personality subdimensions. We respond to three commentaries by distinguished scholars who raise provocative challenges to our arguments and intriguing suggestions for future research. We clarify the role of folk concepts in our understanding of psychopathy, offer further suggestions for testing our interactional hypotheses, consider the role of boldness in motivational accounts of psychopathy, and discuss future directions for incorporating developmental considerations and the role of victims in our EIS account. We are optimistic that this account will prove to be of heuristic value, and should encourage researchers and theoreticians to explore alternative models of psychopathy and other personality disorders.
23
Ramanaiah, Nerella V., and J. Patrick Sharpe. "Structure of the Coolidge Axis II Inventory Personality Disorder Scales from the Five-Factor Model Perspective." Psychological Reports 83, no. 3 (December 1998): 947–52. http://dx.doi.org/10.2466/pr0.1998.83.3.947.
Full textAbstract:
Coolidge, et al. in 1994 tested the generality and comprehensiveness of the five-factor model of personality as applied to personality disorders by performing a canonical correlation analysis for the scales from the Coolidge Axis II Inventory and the NEO Personality Inventory testing 178 undergraduates (106 men and 72 women). Their results did not support the generality and comprehensiveness of the five-factor model for interpreting the structure of personality disorders. A major problem with this study was that the data did not show good simple structure and meaningfulness because no rotation was performed for the canonical variates. The present study tested the hypothesis that the results of Coolidge, et al. might be attributed to the failure to rotate canonical variates to obtain good simple structure. For 220 students in introductory psychology (104 men and 116 women), canonical correlation analysis with varimax rotation was performed for scores on the Coolidge Axis II Inventory scales and the NEO Five-Factor Inventory scales. The analysis indicated five canonical variate pairs which were interpreted as Neuroticism, Extraversion, Openness, Disagreeableness, and Conscientiousness, supporting the tested hypothesis as well as the generality and comprehensiveness of this model for describing the structure of personality disorders.
24
Mortensen, Erik Lykke, Holger Jelling Sørensen, Hans Henrik Jensen, June Machover Reinisch, and Sarnoff A. Mednick. "IQ and mental disorder in young men." British Journal of Psychiatry 187, no. 5 (November 2005): 407–15. http://dx.doi.org/10.1192/bjp.187.5.407.
Full textAbstract:
BackgroundMost research investigating the relationship between IQ and risk of mental disorder has focused on schizophrenia.AimsTo illuminate the relationship between IQ test scores in early adulthood and various mental disorders.MethodFor 3289 men from the Copenhagen Perinatal Cohort, military IQ test scores and information on psychiatric hospitalisation were available. We identified 350 men in the Danish Psychiatric Central Register, and compared the mean IQ test scores of nine diagnostic categories with the mean scores of 2939 unregistered cohort controls.ResultsSchizophrenia and related disorders, other psychotic disorders, adjustment, personality, alcohol and substance-use-related disorders were significantly associated with low IQ scores, but this association remained significant for the four non-psychotic disorders only when adjusting for comorbid diagnoses. For most diagnostic categories, test scores were positively associated with the length of the interval between testing and first admission. ICD mood disorders as well as neuroses and related disorders were not significantly associated with low IQ scores.ConclusionsLow IQ may be a consequence of mental disease or a causal factor in psychotic and non-psychotic disorders.
25
Giora, Asher, Lina Gega, Sabine Landau, and Isaac Marks. "Adult Recall of Having Been Bullied in Attenders of an Anxiety Disorder Unit and Attenders of a Dental Clinic: A Pilot Controlled Study." Behaviour Change 22, no. 1 (March 1, 2005): 44–49. http://dx.doi.org/10.1375/bech.22.1.44.66785.
Full textAbstract:
AbstractLittle is known about the prevalence of having been bullied in adults with versus adults without an anxiety disorder, so a pilot comparison was undertaken. A questionnaire on recall of having been bullied was completed by 81 attenders of a behavioural psychotherapy unit for anxiety disorders and by 81 attenders of a dental clinic who had no psychiatric problems but who were similar to the anxiety disorder group in gender, marital and employment characteristics. Recall of being bullied was significantly more common in the anxiety disorder referrals than in the dental patients. Results warrant testing of whether being bullied as a child increases the likelihood of developing an anxiety disorder in later life, controlling for demographic, personality and ethnic variables.
26
Trimboli, Frank, Charles W. Keenan, and Rycke L. Marshall. "A clinical guide to assessing level of ego development using psychological testing." Bulletin of the Menninger Clinic 83, no. 1 (March 2019): 25–52. http://dx.doi.org/10.1521/bumc.2019.83.1.25.
Full textAbstract:
This article presents a clinical guide for relating psychological test findings from the Minnesota Multiphasic Personality Inventory-2 and Rorschach Technique to various levels of ego development. The original three validity and 10 clinical scales from the MMPI and a selected group of traditional determinants from the Rorschach are employed. Expected testing results from these instruments are derived from both the authors' clinical experience and the research literature. These results are presented along a continuum of nine levels of ego development and their associated disorders. The nine levels of ego development are “normal” neurotic, neurotic trait, and neurotic symptom organization; high-, mid-, and low-level borderline organization; and affective, cognitive-affective, and cognitive psychotic organization. The relationships between typical testing responses and indices of personality functioning at each level of ego development would hopefully facilitate accurate diagnosis, which in turn would result in more effective treatment planning.
27
Gillespie, Nathan A., Steven H. Aggen, Amanda E. Gentry, Michael C. Neale, Gun P. Knudsen, Robert F. Krueger, Susan C. South, et al. "Testing Genetic and Environmental Associations Between Personality Disorders and Cocaine Use: A Population-Based Twin Study." Twin Research and Human Genetics 21, no. 1 (January 25, 2018): 24–32. http://dx.doi.org/10.1017/thg.2017.73.
Full textAbstract:
Until now, data have not been available to elucidate the genetic and environmental sources of comorbidity between all 10 DSM-IV personality disorders (PDs) and cocaine use. Our aim was to determine which PD traits are linked phenotypically and genetically to cocaine use. Cross-sectional data were obtained in a face-to-face interview between 1999 and 2004. Subjects were 1,419 twins (µage = 28.2 years, range = 19–36) from the Norwegian Institute of Public Health Twin Panel, with complete lifetime cocaine use and criteria for all 10 DSM-IV PDs. Stepwise multiple and Least Absolute Shrinkage and Selection Operator (LASSO) regressions were used to identify PDs related to cocaine use. Twin models were fitted to estimate genetic and environmental associations between the PD traits and cocaine use. In the multiple regression, antisocial (OR = 4.24, 95% CI [2.66, 6.86]) and borderline (OR = 2.19, 95% CI [1.35, 3.57]) PD traits were significant predictors of cocaine use. In the LASSO regression, antisocial, borderline, and histrionic were significant predictors of cocaine use. Antisocial and borderline PD traits each explained 72% and 25% of the total genetic risks in cocaine use, respectively. Genetic risks in histrionic PD were not significantly related to cocaine use. Importantly, after removing criteria referencing substance use, antisocial PD explained 65% of the total genetic variance in cocaine use, whereas borderline explained only 4%. Among PD traits, antisocial is the strongest correlate of cocaine use, for which the association is driven largely by common genetic risks.
28
Ballesteros, A., A. Petcu, B. Cortés, L. Montes, F. Inchausti, W. Jaimes, J. Collantes, and B. Zubizarreta. "Differentiating Between Bipolar Affective Disorder (Bd) and Borderline Personality Disorder (BPD) – a Clinical Case." European Psychiatry 33, S1 (March 2016): S504. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1854.
Full textAbstract:
IntroductionRecent studies suggest that Borderline Personality Disorder (BPD) could be regarded as an affective disorder within the Bipolar Affective Disorder (BP) spectrum. This is supported by evidence suggesting a clinical/neurobiological overlap between these two disorders. The Temperament and Character Inventory Revised (TCI-R) may help differentiate between the two disorders and orientate the clinical approach, considering the evidence of the medium-term temporal stability of TCI-R in a clinical population.ObjectiveWe present a clinical case diagnosed with BD which underwent testing using TCI-R. TCI-R orientated towards a secondary diagnosis of BPD and the case further received a course of Dialectical Behavior Therapy (DBT) which led to clinical improvement. We therefore study the usefulness of TCI-R in this clinical setting.AimsTo study whether TCI-R may help differentiate between BD and BPD in mood stabilized patients.MethodOur patient is a 52-year-old married male diagnosed with BD. Considering his clinical features of impulsivity/instability of behaviors and pathological interpersonal relationships, patient was started on individual DBT (fortnightly, 4 months). Psychotropic treatment (paroxetine 30 mg/day, lithium 1000 mg/day, aripiprazole 15 mg/day) was not modified.ResultsTCI-R scores: harm avoidance (100%), novelty seeking (53%), reward dependence (20%), persistence (18%), self-directedness (1%), cooperativeness (2%) and self-transcendence (48%). After 4 months of therapy, the patient improved in distress tolerance, acceptance, behavioral activation and assertiveness.ConclusionsTCI-R is an inventory for personality traits in which character scores differ markedly between PD and non-PD patients. It is a useful tool in BPD patients orientating the clinician in the differential diagnosis and the treatment approach.Disclosure of interestThe authors have not supplied their declaration of competing interest.
29
Cleland, Neil, Samuel Lieblich, Martin Schalling, and Christoffer Rahm. "A 16-year-old girl with anti-NMDA-receptor encephalitis and family history of psychotic disorders." Acta Neuropsychiatrica 27, no. 6 (June 1, 2015): 375–79. http://dx.doi.org/10.1017/neu.2015.32.
Full textAbstract:
BackgroundAutoimmune NMDA-R encephalitis (ANRE) shares clinical features with schizophrenia. Recent research also indicates that both disorders are associated with dysfunction of the N-Methyl-D-Aspartate glutamate receptors (NMDA-R) subunit 1.MethodsWe present the case of Ms A, 16 years old. Ms A presented with acute personality change, bizarre behaviour, delusional ideas and atypical seizures. She had a family history of psychotic disorders, and autistic traits diagnosed in childhood. She was initially diagnosed with a psychotic disorder. Delayed testing of CSF indicated ANRE. As the patient was a Jehovah's witness the treating team was unable to use gammaglobulin therapy; they instead relied on combined plasmapheresis and rituximab. To exclude the possibility that the affected members of this family shared a gene coding for an abnormal configuration of the NMDA receptor subunit 1 we sequenced the region of the GRIN1 gene in DNA extracted from blood in both Ms A and her grandmother.ResultsMs A’s condition improved dramatically, though her long-term memory is still demonstrably impaired. No genetic abnormality was detected.ConclusionsThis case emphasizes how important it is, for a first episode psychosis, to exclude ANRE and other autoimmune synaptic encephalitides, even in the face of significant family history, and if seronegative, the importance of testing for CSF autoantibodies.
30
Bokhan, N., and G. Y. Selivanov. "Clinical Variants of Psychopathological Disorders in Users of Synthetic Cannabinoids (Spices)." European Psychiatry 41, S1 (April 2017): S199—S200. http://dx.doi.org/10.1016/j.eurpsy.2017.01.2146.
Full textAbstract:
IntroductionThe problem of mental health of synthetic (“designer”) drug or “spice” users draws the increasing attention of experts of various areas in psychiatry, addiction psychiatry and psychotherapy.Research objective To classify and describe the psychotic states arising after the use of “spice”; to define the personality changes and probable consequences of the use observed in patients in the conditions of a hospital.Material and methodsOne hundred and one patients (93 men and 8 women; mean age 27.8 ± 7.6 years) with dependence on “spice” revealed between 2014 and 2015 were examined. History taking, clinical-psychopathological investigation and experimental psychological testing were used.Results and discussionAs a result of research the patients were divided into 5 groups according to criteria of ICD-10:– group 1: acute intoxication with delirium (n = 16; 15.84%);– group 2: residual and late-onset psychotic disorders like flashbacks (n = 9; 8.92%);– group 3: withdrawal state with delirium (n = 32; 31.68%);– group 4: psychotic disorder, mainly hallucinatory (n = 30; 29.70%);– group 5: paranoid schizophrenia (n = 14; 13.86%).The use of synthetic cannabinoids (“spice”) can initiate transient psychotic episodes, serve as the contributing factor of development of paranoid schizophrenia, continuous type of the course, leads to “accentuation” of schizoid, paranoid and psychopathic traits of the personality. It is proposed to make up a question of the possibility of additional use of the clarifying designation “synthetic cannabinoids/spice” at reference of patients using synthetic cannabinoids to the section of ICD-10 F12 “Mental and behavioural disorders due to use of cannabinoids” the agenda of clinicians.Disclosure of interestThe authors have not supplied their declaration of competing interest.
31
Haines, Nathaniel, Theodore P. Beauchaine, Matthew Galdo, Andrew H. Rogers, Hunter Hahn, Mark A. Pitt, Jay I. Myung, Brandon M. Turner, and Woo-Young Ahn. "Anxiety Modulates Preference for Immediate Rewards Among Trait-Impulsive Individuals: A Hierarchical Bayesian Analysis." Clinical Psychological Science 8, no. 6 (November 2020): 1017–36. http://dx.doi.org/10.1177/2167702620929636.
Full textAbstract:
Trait impulsivity—defined by strong preference for immediate over delayed rewards and difficulties inhibiting prepotent behaviors—is observed in all externalizing disorders, including substance-use disorders. Many laboratory tasks have been developed to identify decision-making mechanisms and correlates of impulsive behavior, but convergence between task measures and self-reports of impulsivity are consistently low. Long-standing theories of personality and decision-making predict that neurally mediated individual differences in sensitivity to (a) reward cues and (b) punishment cues (frustrative nonreward) interact to affect behavior. Such interactions obscure one-to-one correspondences between single personality traits and task performance. We used hierarchical Bayesian analysis in three samples with differing levels of substance use ( N = 967) to identify interactive dependencies between trait impulsivity and state anxiety on impulsive decision-making. Our findings reveal how anxiety modulates impulsive decision-making and demonstrate benefits of hierarchical Bayesian analysis over traditional approaches for testing theories of psychopathology spanning levels of analysis.
32
Southward, Matthew W., and Jennifer S. Cheavens. "Identifying Core Deficits in a Dimensional Model of Borderline Personality Disorder Features: A Network Analysis." Clinical Psychological Science 6, no. 5 (May 18, 2018): 685–703. http://dx.doi.org/10.1177/2167702618769560.
Full textAbstract:
Researchers have proposed three core deficits of Borderline Personality Disorder (BPD): emotion dysregulation, interpersonal problems, and self-identity disturbance. Previous methods for testing these deficits rest on problematic assumptions (e.g., the assumption that observable/measured features of BPD, such as chaotic relationships and affective intensity, occur independently). A network model of psychopathology assumes that observable features of disorders directly interact, and network analytic methods quantify how central each feature is. We conducted a network analysis of core deficits of BPD features using a large ( N = 4,386) sample of participants with a range of BPD features. The most central features of participants in the High BPD group were loneliness, recklessness/impulsivity, and intense moods, supporting models of emotion dysregulation and interpersonal problems. The networks of BPD features did not differ between men and women. We provide directions for future research to enhance our understanding of how networks of BPD features change over time.
33
Mauri, Massimo C., Giovanna Cirnigliaro, Chiara Di Pace, Silvia Paletta, Alessandra Reggiori, Carlo A. Altamura, and Bernardo Dell’Osso. "Aggressiveness and violence in psychiatric patients: a clinical or social paradigm?" CNS Spectrums 24, no. 5 (February 4, 2019): 564–73. http://dx.doi.org/10.1017/s1092852918001438.
Full textAbstract:
ObjectivePsychiatric disorders are often considered the leading cause of violence. This may be due to a stereotype created by media and general opinion.MethodThe Modified Overt Aggression Scale (MOAS) was used to evaluate the severity of aggressive and violent behaviors in 400 patients who attended a post-acute psychiatric service in Milan from 2014 to 2016 and suffered from different psychiatric disorders. The psychopathological clinical picture was evaluated by Clinical Global Impression (CGI). The study also assessed the possible correlation between epidemiologic and sociodemographic factors, clinical variables, and aggression and violence.ResultsOf the total number of subjects, 21.50% showed a MOAS score >0, 11.50% presented mild aggression (0–10 MOAS weighted score), 9% moderate aggression (11–20), and 1% severe aggression (MOAS >20). With respect to violent behaviors, 16% of patients showed a score >0 in one MOAS subscale other than verbal aggression according to violence definition. The severity of clinical picture seemed to be related to higher weighted MOAS score. Multivariate testing of different sociodemographic and clinical variables showed that violence was related to unemployment status, and significantly correlated to compulsory admission (TSO), suicide attempts (TS), and personality disorders, while the severity of clinical psychiatric picture seemed to play a secondary role.ConclusionResults have shown that personality disorders and sociodemographic factors, including economic factors, seem to be major determinants of violence among patients diagnosed with mental disorders.
34
Anaf, G. M., and S. J. Rosenman. "The Detection of Alcohol Use in Psychiatric Casualty Patients." Australian & New Zealand Journal of Psychiatry 19, no. 4 (December 1985): 439–42. http://dx.doi.org/10.1080/00048678509158853.
Full textAbstract:
This study assessed the extent of alcohol use among casualty attenders at a metropolitan psychiatric hospital. Seventeen of 97 patients showed measurable alcohol levels at the time of presentation. Patients with functional psychoses used alcohol excessively, but the heaviest and most frequent use was among women, especially those with personality disorders. It is suggested that routine alcohol testing is worthwhile and inexpensive, and it may lead to earlier detection and treatment of alcohol abuse.
35
McNeill, Rhiannon V., Georg C. Ziegler, Franziska Radtke, Matthias Nieberler, Klaus-Peter Lesch, and Sarah Kittel-Schneider. "Mental health dished up—the use of iPSC models in neuropsychiatric research." Journal of Neural Transmission 127, no. 11 (May 7, 2020): 1547–68. http://dx.doi.org/10.1007/s00702-020-02197-9.
Full textAbstract:
Abstract Genetic and molecular mechanisms that play a causal role in mental illnesses are challenging to elucidate, particularly as there is a lack of relevant in vitro and in vivo models. However, the advent of induced pluripotent stem cell (iPSC) technology has provided researchers with a novel toolbox. We conducted a systematic review using the PRISMA statement. A PubMed and Web of Science online search was performed (studies published between 2006–2020) using the following search strategy: hiPSC OR iPSC OR iPS OR stem cells AND schizophrenia disorder OR personality disorder OR antisocial personality disorder OR psychopathy OR bipolar disorder OR major depressive disorder OR obsessive compulsive disorder OR anxiety disorder OR substance use disorder OR alcohol use disorder OR nicotine use disorder OR opioid use disorder OR eating disorder OR anorexia nervosa OR attention-deficit/hyperactivity disorder OR gaming disorder. Using the above search criteria, a total of 3515 studies were found. After screening, a final total of 56 studies were deemed eligible for inclusion in our study. Using iPSC technology, psychiatric disease can be studied in the context of a patient’s own unique genetic background. This has allowed great strides to be made into uncovering the etiology of psychiatric disease, as well as providing a unique paradigm for drug testing. However, there is a lack of data for certain psychiatric disorders and several limitations to present iPSC-based studies, leading us to discuss how this field may progress in the next years to increase its utility in the battle to understand psychiatric disease.
36
Arkhipov, V. V., E. K. Abakumova, Ya S. Dmitrieva, N. I. Zykova, and Yu R. Bolsunovskaya. "Analysis of the Clinical Case of Long-term Monitoring of a Patient with Comorbid Depression: Special Considerations of Psychopharmacotherapy." Safety and Risk of Pharmacotherapy 8, no. 2 (June 26, 2020): 90–103. http://dx.doi.org/10.30895/2312-7821-2020-8-2-90-103.
Full textAbstract:
Depression associated with somatic diseases ranks high among other depressive disorders and has a number of specifi c clinical features as compared to classic depression.The aim of the study was to analyse specifi c features of comorbid depression clinical course, its diagnosis, and methodology for the selection of psychopharmacotherapy—using a clinical case as an example.Results: the authors carried out a detailed retrospective clinical analysis of medical records of long-term (over three years) dynamic monitoring of a patient with comorbid vascular depression. They explored the tactics of selecting pharmacotherapy for anxiety-depressive disorder given the underlying chronic cerebral ischemia, atherosclerosis of brachiocephalic arteries, аrterial hypertension, and atherosclerotic cardiosclerosis. The primary focus was on specifi c aspects of vascular depression pharmacotherapy that were governed by a diverse clinical picture of comorbid personality disorders, dynamic transformation of somatic, neurological, and psychic symptoms and syndromes in a patient. The paper highlights the need for alignment of scientifi c and methodological approaches to assessment of potential risks associated with the use of psychotropic medicines.Conclusions: the choice of rational psychopharmacotherapy for vascular depression should be governed by the data on the drug effi cacy for the prevailing clinical symptoms, by the age and gender characteristics of the patient, by compensation status of organs and systems, as well as by genetic, personal, and social characteristics that aff ect the disease progression. The use of a comprehensive multidisciplinary approach to the diagnosis and treatment of comorbid personality disorders, as well as implementation of personalised medicine methodology in clinical practice in order to assess the patient’s condition as infl uenced by changes in his/her somatic, neurological, psychic status and the results of psychological testing, will increase the effi cacy and safety of treatment.
37
Tsumarieva, Natalia. "Theoretical and empirical study of the phenomenon of emotional deprivation." Scientific Visnyk V.O. Sukhomlynskyi Mykolaiv National University. Psychological Sciences, no. 2 (21) (2021): 62–69. http://dx.doi.org/10.33310/2078-2128-2021-21-2-62-69.
Full textAbstract:
The aim of this article is the implementation of theoretical and empirical analysis of the essence of emotionality. Methods of study: analysis, comparison and systematization of the scientific literature concerning the phenomenon of an emotional deprivation, observation, analysis of the documentation, the method of the peer review, a conversation, a testing, a survey for the identification of the consequences of the emotional deprivation. Results. We figured out that emotional deprivation very closely connected with other kinds of deprivation and is part of the mental deprivation. The semantic content of the notion "emotional deprivation" depends on the conceptual and theoretical approaches of the author, studying of the specific conditions of its origin and also the specific of age group. However most scientists continue determine emotional deprivation as a category of mental state of the personality. Emotional deprivation is an instrument of change and transformation in the psychics, affects somatic health, causes psychosomatic disorders and mental disorders. It is generalized that emotional deprivation through negative feelings and emotions affects other mental spheres of personality – volitional, intellectual, motivational, value-oriented, changing them, deforming, complicating, ie affects the psyche in general. Conclu s ion s . Emotional deprivation can't be equated as a mental state, because it is connected indirectly with the mental state of the deprived personality, but it isn't one. To our mind, emotional deprivation is a process of long lasting stay of the personality in conditions of emotionally impoverished environment, conditioned by displeasure of emotional needs, loss, limitation, insufficiency or absence of abilities for installation of close connections, contacts and interaction with a significant person. It causes dysfunction, breaches and disarrays of the mental sphere of a personality.
38
Simonenko, Grigoriy. "DETECTION OF AUTONOMIC DYSFYNCTIONS IN COMPLEX NEUROPSYCHOLOGICAL EXAMINATION OF NMU STUDENTS." EUREKA: Health Sciences 4 (July 31, 2017): 12–17. http://dx.doi.org/10.21303/2504-5679.2017.00384.
Full textAbstract:
According to the data of the world statistics there is observed the growth of autonomic dysfunctions. It is one of the main problems of clinical neurology: 12–25 % of children and near 70 % of adults suffers from these disorders. Aim: diagnosing of autonomic dysfunctions in the contingent of students with the help of neuropsychological investigations. Methods and materials: There were examined 1379 students of medical university. Self-appraisal autonomic system tone testing, Kerdo index, G.Dagnini-B.Aschner reflex and ortho-clinostatic sign were carried out on the first phase. For 157 students the Heart Rate Variability was investigated on the second phase. All students were tested by the Eysenck Personality Inventory on the third phase. 70 students (31 men, 39 women) were accordingly tested by the Minnesota Multiphasic Personality Inventory. Results of research: Increasing of sympathetic part of the autonomic nervous system showed 221 (82.1 %) from 257 persons. Kerdo index was positive at 156 (60.7 %) persons. Reactivity of the autonomic nervous system by the G.Dagnini-B.Aschner reflex showed sympathetic reaction in 133 (51.8 %) persons. Autonomic ensuring of the vital functions study by ortho-clinostatic sign also showed prevalence of the sympathetic reaction – 150 (58.4 %) students. According to the RSAI, 5 marks (optimal) were showed in case of 52 (33.1 %) students. 4 marks – 68 (43.3 %) persons. 3, 2 and 1 marks were registered in case of 26 (16.6 %) persons. Average SI was 168.47 ± 16.42. 4 marks of RSAI correlated with SI=137.29 ± 5.75, 2 marks correlated with SI=508.12 ± 32.12. According to psychological tests, all students with extraversion reliably showed non-stability of the higher nervous action (14.38±017), increased average T-marks of F-scale (77±1.949), 9-scale (71±1.553) and 8-scale (71±1.801). Conclusions: Indicators of autonomic tone, autonomic reactivity and autonomic activity ensuring showed prevalence of sympathicotonia in contingent of students. Heart Rate Variability investigation found dystonic disorders of autonomic nervous system of supra-segmental level mainly. Eysenck Personality Inventory found the prevalence of extraversion and non-stability of the higher nervous activity what may indicate further autonomic dysfunctions. Minnesota Multiphasic Personality Inventory testing revealed psychological disproportions with prevalence of hypomanic, paranoid, schizophrenic tendency. Psychologic affects cause further somatic complaints as manifestation of autonomic dysfunctions.
39
Rozhnova, T. M., S. V. Kostyuk, V. L. Malygin, S. N. Enikolopov, and V. N. Nikolenko. "The phenomenon of codependency: psychological and medical genetic aspects." Neurology, Neuropsychiatry, Psychosomatics 12, no. 5 (October 25, 2020): 53–59. http://dx.doi.org/10.14412/2074-2711-2020-5-53-59.
Full textAbstract:
Addictive behavioral disorders are multifactorial diseases with clinical, neurophysiological, and genetic heterogeneity, a high comorbidity with other disorders, and a low curability. The etiopathogenetic mechanisms of non-chemical forms of addictive behavior have not been sufficiently studied, which makes it difficult to search for effective therapeutic procedures.Objective: to study the psychological and genetic components of a non-chemical addictive disorder as the phenomenon of codependency.Patients and methods. The investigation enrolled 256 women who were divided into three comparison groups: 1) those with the phenomenon of codependency, 2) phenotypically healthy women; 3) a population sample. Psychometric testing was carried out using the «Hand Test» by E. Wagner (adapted by A.I. Gerasimov and S.N. Enikolopov) and the clinical and genealogical characteristics of women with the phenomenon of codependency were studied. Results and discussion. There was a statistically significant predominance of the level of aggressiveness as autoaggression in the structure of the personality profile of women with the phenomenon of codependency (t=2.924–3.015; p=0.004–0.005). The clinical and genealogical characteristics of persons with addictive behavioral disorder as the phenomenon of codependency suggest that there is a statistically significantly high frequency of secondary alcoholism among first-degree and second-degree relatives or both and first-degree male relatives (p<0.001).Conclusion. The phenomenon of codependency as a non-chemical addiction includes psychological and genetic components. Women with codependency had autoaggressive destructive behavior patterns and a family history of alcoholism. The identified psychogenic characteristics can be considered as a risk for an addictive disease and somatoform disorders.
40
Um, Miji, Zachary Whitt, Rebecca Revilla, Taylor Hunton, and Melissa Cyders. "Shared Neural Correlates Underlying Addictive Disorders and Negative Urgency." Brain Sciences 9, no. 2 (February 8, 2019): 36. http://dx.doi.org/10.3390/brainsci9020036.
Full textAbstract:
Negative urgency is a personality trait reflecting the tendency to act rashly in response to extreme negative emotions and is considered a transdiagnostic endophenotype for problematic levels of addictive behaviors. Recent research has begun to identify the neural correlates of negative urgency, many of which appear to overlap with neural circuitry underlying addictive disorders associated with negative urgency. The goal of this qualitative review is to summarize the extant literature concerning the neural correlates of negative urgency, to compare these correlates with those implicated with addictive disorders, and to propose new ways to begin to leverage such findings in treatment and intervention approaches. We also address current limitations in the field and make recommendations for areas for future growth in this research domain. Patterns of structure and function in the ventral striatum, frontal regions, such as the prefrontal cortex (PFC) and orbitofrontal cortex (OFC), and amygdala are common across addictive disorders and are related to both real-world risky behaviors and self-report measures of negative urgency. We propose that the time has come to move past considering this trait and these disorders as completely separate entities, and instead for the field to consider how general patterns of convergence across these disorders can lead to a more transdiagnostic approach to treatment and intervention. We suggest future work utilize these convergent patterns in the development of animal models of negative urgency, in the identification and testing of prime pharmacological and physiological interventions, and as objective biomarkers to be used when testing behavioral, pharmacological, and physiological intervention effectiveness. Little empirical work has been done to date in these areas and advances in these nascent fields would advance understanding and applications of the neuroscience of negative urgency.
41
Ducharme, Simon, Annemiek Dols, Robert Laforce, Emma Devenney, Fiona Kumfor, Jan van den Stock, Caroline Dallaire-Théroux, et al. "Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders." Brain 143, no. 6 (March 4, 2020): 1632–50. http://dx.doi.org/10.1093/brain/awaa018.
Full textAbstract:
Abstract The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-onset dementia. The diagnosis of bvFTD remains challenging because of the limited accuracy of neuroimaging in the early disease stages and the absence of molecular biomarkers, and therefore relies predominantly on clinical assessment. BvFTD shows significant symptomatic overlap with non-degenerative primary psychiatric disorders including major depressive disorder, bipolar disorder, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders and even personality disorders. To date, ∼50% of patients with bvFTD receive a prior psychiatric diagnosis, and average diagnostic delay is up to 5–6 years from symptom onset. It is also not uncommon for patients with primary psychiatric disorders to be wrongly diagnosed with bvFTD. The Neuropsychiatric International Consortium for Frontotemporal Dementia was recently established to determine the current best clinical practice and set up an international collaboration to share a common dataset for future research. The goal of the present paper was to review the existing literature on the diagnosis of bvFTD and its differential diagnosis with primary psychiatric disorders to provide consensus recommendations on the clinical assessment. A systematic literature search with a narrative review was performed to determine all bvFTD-related diagnostic evidence for the following topics: bvFTD history taking, psychiatric assessment, clinical scales, physical and neurological examination, bedside cognitive tests, neuropsychological assessment, social cognition, structural neuroimaging, functional neuroimaging, CSF and genetic testing. For each topic, responsible team members proposed a set of minimal requirements, optimal clinical recommendations, and tools requiring further research or those that should be developed. Recommendations were listed if they reached a ≥ 85% expert consensus based on an online survey among all consortium participants. New recommendations include performing at least one formal social cognition test in the standard neuropsychological battery for bvFTD. We emphasize the importance of 3D-T1 brain MRI with a standardized review protocol including validated visual atrophy rating scales, and to consider volumetric analyses if available. We clarify the role of 18F-fluorodeoxyglucose PET for the exclusion of bvFTD when normal, whereas non-specific regional metabolism abnormalities should not be over-interpreted in the case of a psychiatric differential diagnosis. We highlight the potential role of serum or CSF neurofilament light chain to differentiate bvFTD from primary psychiatric disorders. Finally, based on the increasing literature and clinical experience, the consortium determined that screening for C9orf72 mutation should be performed in all possible/probable bvFTD cases or suspected cases with strong psychiatric features.
42
Christiaens, F., and M. Maes. "The TRH-test in depression: a review." Acta Neuropsychiatrica 4, no. 4 (December 1994): 71–76. http://dx.doi.org/10.1017/s0924270800034116.
Full textAbstract:
SummaryThe TRH-test in depression: a reviewThis paper reviews the literature on the thyrotropin releasing hormone (TRH)-test in depressive patients. The TRH-test appears to exhibit some use as an external validating criterion for the clinical diagnosis of major depression and, in particular melancholia versus minor depression once the clinical diagnosis depression is made. However, the clinical use of this test is hampered by the low sensitivity (±50%) and by the fact that abnormal tests occur in non-depressive states such as borderline personality disorder, schizophrenia, and anxiety disorders. The TRH-test may be used as a predictor for a positive response to biological therapies. In addition, the test has some value for the outcome of a depressive episode. The pathophysiology underpinning an abnormal TRH-test may be determined by noradrenergic (central and peripheric) or serotonergic (central) dysfunctions, thyroid hormone and cortisol hypersecretion, phenomena that are pertinent to severe depression. Recently, it has been established that an abnormal depression-linked TRH-test reflects lower basal thyroid secreting hormone (TSH) secretion. The determination of basal TSH may, in the future, replace TRH-testing.
43
Hart, Daniel, and Naomi R. Marmorstein. "Neighborhoods and genes and everything in between: Understanding adolescent aggression in social and biological contexts." Development and Psychopathology 21, no. 3 (July 7, 2009): 961–73. http://dx.doi.org/10.1017/s0954579409000510.
Full textAbstract:
AbstractAdolescent aggression was explored in relation to neighborhood and genetic characteristics. Child saturation (the proportion of the population consisting of children under the age of 15), ethnic heterogeneity, poverty, and urbanicity of neighborhoods were examined in relation to adolescent aggression in 12,098 adolescents followed longitudinally for 1 year. Longitudinal analyses indicated that child saturation was positively associated with increases in aggression, with this finding emerging among those living in the same neighborhood at both testing times and those who moved between testing times. In a subsample of males for whom genetic data were available, the relation of child saturation to adolescent aggression was moderated by the monoamine oxidase A (MAOA) gene. The regression of aggression on child saturation was steeper for those with the low activity version of the MAOA allele than among those with the high activity version of the allele. The implications of the results for an understanding of the origins and ontogeny of aggression and personality disorders are discussed.
44
Waters, F., J. D. Blom, R. Jardri, K. Hugdahl, and I. E. C. Sommer. "Auditory hallucinations, not necessarily a hallmark of psychotic disorder." Psychological Medicine 48, no. 4 (August 22, 2017): 529–36. http://dx.doi.org/10.1017/s0033291717002203.
Full textAbstract:
Auditory hallucinations (AH) are often considered a sign of a psychotic disorder. This is promoted by the DSM-5 category of Other Specified Schizophrenia Spectrum And Other Psychotic Disorder (OSSSOPD), the diagnostic criteria for which are fulfilled with the sole presence of persistent AH, in the absence of any other psychotic symptoms. And yet, persistent AH are not synonymous with having a psychotic disorder, and should therefore not be uncritically treated as such. Many people who seek treatment for persistent AH have no other psychotic symptoms, have preserved reality-testing capacities, and will never develop a schizophrenia spectrum disorder. Instead, hallucinations may be the result of many different causes, including borderline personality disorder, post-traumatic stress disorder (PTSD), hearing loss, sleep disorders or brain lesions, and they may even occur outside the context of any demonstrable pathology. In such cases, the usage of the DSM-5 diagnosis of OSSSOPD would be incorrect, and it may prompt unwarranted treatment with antipsychotic medication. We therefore argue that a DSM-5 diagnosis of Schizophrenia Spectrum Disorder (or any other type of psychotic disorder) characterized by AH should require at least one more symptom listed under the A-criterion (i.e. delusions, disorganized speech, disorganized or catatonic behavior or negative symptoms). Adhering to these more stringent criteria may help to distinguish between individuals with persistent AH which are part of a psychotic disorder, for whom antipsychotic medication may be helpful, and individuals with AH in the absence of such a disorder who may benefit from other approaches (e.g. different pharmacological interventions, improving coping style, trauma-related therapy).
45
Wilson, Janet A., I. J. Deary, and A. G. D. Maran. "Is Globus Hystericus?" British Journal of Psychiatry 153, no. 3 (September 1988): 335–39. http://dx.doi.org/10.1192/bjp.153.3.335.
Full textAbstract:
Forty-six patients, 9 male, 37 female, presenting to an ear, nose and throat department with a principal complaint of globus sensation were investigated by radiology, manometry, endoscopy and prolonged ambulatory pH monitoring to exclude a physical basis for their symptoms. Patients also underwent assessment by the Eysenck Personality Inventory (EPI) and General Health Questionnaire (GHQ). The only organic abnormalities detected were an abnormal degree of oesophageal acid exposure (seven patients) and oesophageal spasm (one patient). Female patients were neurotic introverts on EPI testing; males were stable ambiverts. High GHQ scores were present in 13 females (35%) and one male and there was a significant correlation between N scores (in the EPI) and GHQ scores. We propose that globus is a useful, single-symptom model for the study of conversion disorders.
46
Chiappini, S., R. Testa, F. Maisto, B. Leone, M. Di Paolo, M. Pascucci, P. Polidori, P. Grandinetti, and G. Conte. "Compulsiveness dimension in a case of pathological gambling." European Psychiatry 33, S1 (March 2016): S294. http://dx.doi.org/10.1016/j.eurpsy.2016.01.999.
Full textAbstract:
IntroductionPathological gambling (PG) is currently included among Addictive Disorders (DSM-5). However, its phenomenology resembles features of Obsessive Compulsive Disorder. Several models of addiction conceptualize a progression from impulsivity to compulsivity transitioning from initial positive reinforcement motivations to later negative reinforcement and less pleasurable and automaticity mechanisms.Clinical presentationA 34-year-old male, since diagnosed with PG in 2013 and prescribed a group rehabilitation therapy, presented in 2015 complaining of intrusive thoughts and depression symptoms. During the psychiatric examination emerged: low mental concentration; dysphoria; hyporexia; irritability; insomnia; persistent ideas and excessive preoccupations to be betrayed by his girlfriend; and behaviours of hyper control on her life. He has been evaluated using MMPI-2 (obsessivity Tscore 70, depression Tscore 67) and BIS-11 (high score of non-planning impulsiveness).TreatmentIt appeared there was a shift from ego-syntonic novelty driven/impulsive behaviours focused primarily on gambling to ego-dystonic habit driven/compulsive behaviours focused on her girlfriend. He started an individual psychodynamic psychotherapy centred on dysfunctional beliefs and behavioural strategies for treating the compulsive features. As thought content was the most relevant aspect, he was prescribed olanzapine, not a SSRI (normally indicated for OCD), up to 10 mg/die. After a month obsessions and compulsions reduced, and he seemed to reach a good level of personal functioning, despite a rigid anankastic personality trait.ConclusionsAs the management of compulsive behaviours is complex, physician should better assess and recognize psychological personality aspect, collecting patients’ complete history, also testing them psychometrically, and paying more attention to an eventual treatment (both psychological and pharmacological).Disclosure of interestThe authors have not supplied their declaration of competing interest.
47
Miller, Catherine R., Nobby C. Mambo, Jianli Dong, and Gerald A. Campbell. "A Case of Previously Unsuspected Huntington Disease Diagnosed at Autopsy." Academic Forensic Pathology 7, no. 1 (March 2017): 136–44. http://dx.doi.org/10.23907/2017.016.
Full textAbstract:
Huntington disease (HD) is a neurodegenerative disorder with a worldwide prevalence of four to ten per 100 000. It is characterized by choreiform movements, behavioral/psychiatric disturbances, and eventual cognitive decline. Symptoms usually present between 30 and 50 years of age and the diagnosis is based on the combination of clinical symptoms, family history, and genetic testing. A variation of HD, juvenile Huntington disease (JHD), presents earlier, with more severe symptoms and with a worse prognosis. Symptoms are different in JHD, with personality changes and learning difficulties being the predominant presenting features. Seizures are common in JHD, and chorea is uncommon; movement disorders at presentation of JHD are predominantly nonchoreiform. The inheritance pattern for both HD and JHD is autosomal dominant and the disease is caused by an elongation of the CAG repeat in the huntingtin gene. There are many published case reports of Huntington disease that were confirmed at autopsy, but to our knowledge, there are no reports in the literature where the diagnosis of Huntington disease was first made at autopsy. We present a case of a 28-year-old African-American male who was in a state of neglect due to a lifetime of abuse, cognitive difficulties, and seizures, whose cause of death was pneumonia. The gross autopsy findings included bilateral caudate nucleus atrophy and lateral ventricular dilation. Microscopically, severe bilateral neuronal loss and gliosis of the caudate and putamen nuclei were seen. Genetic testing for the number of CAG repeats confirmed the diagnosis and was consistent with JHD.
48
Budenz, Alexandra, Amanda Klein, and Yvonne Prutzman. "The Relationship Between Trauma Exposure and Adult Tobacco Use: Analysis of the National Epidemiologic Survey on Alcohol and Related Conditions (III)." Nicotine & Tobacco Research 23, no. 10 (April 13, 2021): 1716–26. http://dx.doi.org/10.1093/ntr/ntab057.
Full textAbstract:
Abstract Introduction Previous research has examined cigarette smoking in trauma exposed populations. However, the relationships between trauma exposure and use of other tobacco products (eg, cigars, e-cigarettes) and specific trauma exposure characteristics that may be associated with tobacco use are understudied. Aims and Methods Using the 2012–2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (N = 36 151 adults), we conducted weighted bivariate analyses of tobacco use among participants with no trauma exposure, trauma exposure, and trauma exposure with post-traumatic stress disorder (trauma + PTSD), stratified by tobacco product use. We also performed weighted logistic regressions testing relationships between trauma exposure and tobacco use, controlling for behavioral health (BH) conditions (mood, anxiety, substance use, personality disorders) and sociodemographics. Results Approximately 44% of participants had experienced trauma; 6% experienced trauma + PTSD. Trauma exposed participants had a higher prevalence of tobacco use (30%––46% vs. 22%) and poly-tobacco use (34%––35% vs. 28%) than unexposed participants. Cigarettes were the most used tobacco product; trauma + PTSD (19%), and trauma (15%) participants had a higher prevalence of e-cigarette use than unexposed participants (11%). Trauma exposure was associated with current tobacco use (AOR = 1.36 trauma + PTSD; 1.23 trauma) (but not former use), particularly among participants exposed to violence/abuse (AOR = 1.23). Personality and substance use disorders were strongly associated with current and former tobacco use. Conclusions Trauma exposure, PTSD, and experiences of violence/abuse are associated with current tobacco use. BH conditions may also play a role in current and former tobacco use. Recognizing and addressing trauma exposure and BH conditions among tobacco users may improve cessation rates in these populations. Implications This study contributes to research on tobacco use disparities in behavioral health populations by providing a comprehensive examination of tobacco use in trauma exposed individuals. Prior research has examined cigarette smoking, but not other tobacco product use in these populations. This study presents findings on multiple tobacco use behaviors (tobacco product, poly-tobacco use, cessation attempts) in trauma exposed populations and characteristics of trauma exposure (severity, type of traumatic event) associated with tobacco use. These findings underscore the importance of further examining the implications of trauma exposure for tobacco use and of screening and addressing trauma in cessation treatment.
49
Attademo, Luigi, Francesco Bernardini, and Norma Verdolini. "S9. NEUROIMAGING AND NEUROPHYSIOLOGY BIOMARKERS OF SCHIZOTYPAL PERSONALITY DISORDER: A SYSTEMATIC REVIEW." Schizophrenia Bulletin 46, Supplement_1 (April 2020): S33. http://dx.doi.org/10.1093/schbul/sbaa031.075.
Full textAbstract:
Abstract Background Schizotypal personality disorder (SPD) is a cluster A personality disorder affecting 1.0% of general population, characterised by disturbances in cognition and reality testing dimensions, affect regulation, and interpersonal function. SPD shares similar but attenuated phenomenological, genetic, and neurobiological abnormalities with schizophrenia (SCZ) and is described as part of the continuum of schizophrenia spectrum disorders. Neuroimaging and neurophysiology are the main non-invasive techniques for the investigation of brain structure and function, so they play a crucial role in psychiatric research and for their applications into clinical practice. The present review aims to systematically identify the major neuroimaging and neurophysiology biomarkers of SPD. Methods The present review has been conducted according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The protocol was prospectively registered in PROSPERO - International prospective register of systematic reviews. The systematic review was performed to summarise the most comprehensive and updated evidence on functional neuroimaging and neurophysiology findings obtained through different techniques (DW-MRI, DTI, PET, SPECT, fMRI, MRS, EEG) in subjects with SPD. Results The search initially yielded 218 records. After study selection and reference screening, the final set comprised 52 studies. Of the 52 studies included in this review, 9 were on DW-MRI and DTI, 11 were on PET and SPECT, 11 were on fMRI and MRS, and 21 were on EEG. Although it was complex to synthesise all the functional abnormalities found in the included studies into a single, unified, pathogenetic pathway, a common theme that emerged was the dysfunction of brain circuits including striatal, frontal, temporal, limbic regions, and their networks. This dysfunction may be the result of a dysregulation along the dopaminergic pathways and lead to deficits or defects in processes that organise a person’s cognitive-perceptual evaluation of the environment and the relatedness to him/herself. As for the limitations, a quantitative data synthesis was not planned for this work, therefore no meta-analytical integrations are presented in this review. The results of individual neuroimaging studies, in fact, are not comparable due to small and heterogeneous samples, analytical flexibility, or differences in imaging modalities and behavioral tasks. Discussion Brain abnormalities in SPD are similar, but less marked, than those found in SCZ, and they do not mirror each other. In fact, different patterns of functional abnormalities in SPD and SCZ have been found in this systematic review, suggesting the ‘presence’ of possible compensatory factors, protecting subjects with SPD from frank psychosis and providing diagnostic specificity. Specifically, SPD differentiates from SCZ by showing: (a) milder frontal-striatal-temporal white matter dysconnectivity in DTI studies, (b) lesser frontal and striatal dysfunction and a decreased striatal dopaminergic activity in PET and SPECT studies, respectively, (c) different patterns of dysfunctional activation of frontal-striatal-thalamic circuitry during attentional processing in fMRI studies, and (d) milder alterations in EEG sensory gating and no evidence of alterations in EEG auditory or visual processing.
50
Russell, Janice D., and Milton G. Roxanas. "Psychiatry and the Frontal Lobes." Australian & New Zealand Journal of Psychiatry 24, no. 1 (March 1990): 113–32. http://dx.doi.org/10.3109/00048679009062894.
Full textAbstract:
The frontal lobes of the brain have long been regarded as enigmatic in their function and perhaps should be considered even more so in states of dysfunction. Observed associations between structural lesions and psychiatric symptoms and the demonstration of disturbed function and morphology in the frontal lobes of individuals suffering from major psychiatric disorders have led to increased interest in this brain area. Psychiatrists have been particularly concerned with seeking the aetiogenesis of common diagnostic entities and this article attempts to synthesize the available facts. A brief overview of relevant biological data precedes a description of methods of neuropsychological testing and the clinical features arising from frontal lobe damage. A discussion of the role of the frontal lobes in some aspects of personality function follows. Neuropsychiatric features associated with known frontal lobe pathology are described, prefacing a discussion of those psychiatric conditions where an aetiological role for frontal lobe dysfunction has been proposed.