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1

Schneider, Ferenc, Éva Stánitz, Judit Kalácska, Tünde Tompity, and Beáta Gábor. "Whooping cough in an urban high school in Hungary. Conclusions of a local pertussis outbreak." Orvosi Hetilap 150, no. 33 (2009): 1557–61. http://dx.doi.org/10.1556/oh.2009.28655.

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A pertussis a védőoltás bevezetésével fokozatosan visszaszoruló fertőző betegség lett, de teljes eradikációja nem lehetséges. Ezt mutatják a nemzetközi és a hazai adatok is. Az ezredforduló után a pertussisos megbetegedések lassú növekedése figyelhető meg. Célkitűzés: Az adolescens pertussis klinikumának bemutatása egy helyi járvány kapcsán, ezzel egyidejűleg a pertussis jelenlétének demonstrálása a hazai populációban. Módszer: Az első felismert 18 éves beteg környezetében retrospektív adatgyűjtéssel felderített, tartósan köhögő betegektől vett vérmintából emelkedő pertussis-antitoxin-IgG megh
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2

Juliska, Shelly, Rico J. Sitorus, and Hamzah Hasyim. "FAKTOR RISIKO KEJADIAN PERTUSIS PADA BAYI DAN ANAK – ANAK (SISTEMATIK LITERATURE REVIEW)." Mitra Raflesia (Journal of Health Science) 16, no. 2 (2024): 50–58. https://doi.org/10.51712/mitraraflesia.v16i2.394.

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ABSTRAKPendahuluan: Kebangkitan (resurgence) pertusis saat ini terjadi hampir di seluruh dunia dengan insiden tertinggi terjadi pada bayi dan menyebabkan kematian pada kasus pertusis berat. Kasus kematian yang terjadi umumnya ditemukan pada bayi berusia < 6 bulan akibat komplikasi pertusis. Tujuan dari penyusunan studi literature ini adalah untuk mempelajari tentang faktor risiko infeksi pertusis pada bayi dan anak-anak. Metode : Metode yang digunakan yaitu studi literatur (literature review) Â yang disusun melalui penelusuran literatur terkait pertusis menggunakan metode PRISMA (Preferred
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3

Tjahjowargo, Sendy, and Hartono Gunardi. "Perbandingan Efektivitas dan Keamanan Vaksin Pertusis Aselular dan Whole-cell." Sari Pediatri 18, no. 5 (2017): 403. http://dx.doi.org/10.14238/sp18.5.2017.403-8.

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Latar belakang. Imunisasi merupakan upaya pencegahan terbaik terhadap berbagai penyakit infeksi. Vaksin difteri, tetanus, pertusis whole-cell (DTwP) dapat menimbulkan kejadian ikutan pasca imunisasi (KIPI) yang mengkhawatirkan orangtua. Vaksin difteri, tetanus, pertusis aselular (DTaP) memiliki KIPI lebih ringan, tetapi diduga kurang efektif. Tujuan. Mengetahui efektivitas vaksin DTaP dibandingkan dengan vaksin DTwP.Metode. Penelusuran literatur elektronik PubMed dan Cochrane dengan kata kunci “DTaP/acellular pertussis”, “DTwP/whole-cell pertussis”, “children”, “pertussis”, “vaccine” and “safe
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4

Zadorozhnaya, V. I., A. P. Podavalenko, and N. I. Operchuk. "Risk of an Intensification of Pertussis Epidemic and its Vaccinal Prevention Process in Ukraine." Epidemiology and Vaccine Prevention 14, no. 1 (2015): 78–82. http://dx.doi.org/10.31631/2073-3046-2015-14-1-78-82.

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The pertussis epidemic process is characterized by cyclical ups 2-5 years, high level of child and town population morbidity. Longterm pertussis morbidity dynamics in Ukraine tends to increase. Low coverage of a pertusiss immunization of the children's population, increase of immunocompromised individuals in the population, deterioration of social, economic and ecological factors are adverse conditions for a current of the pertussis epidemic process. The first priority is to maintain an appropriate level of routine immunization of children with increased attention to immunocompromised persons.
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5

Kilgore, Paul E., Abdulbaset M. Salim, Marcus J. Zervos, and Heinz-Josef Schmitt. "Pertussis: Microbiology, Disease, Treatment, and Prevention." Clinical Microbiology Reviews 29, no. 3 (2016): 449–86. http://dx.doi.org/10.1128/cmr.00083-15.

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SUMMARYPertussis is a severe respiratory infection caused byBordetella pertussis, and in 2008, pertussis was associated with an estimated 16 million cases and 195,000 deaths globally. Sizeable outbreaks of pertussis have been reported over the past 5 years, and disease reemergence has been the focus of international attention to develop a deeper understanding of pathogen virulence and genetic evolution ofB. pertussisstrains. During the past 20 years, the scientific community has recognized pertussis among adults as well as infants and children. Increased recognition that older children and ado
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6

Conly, John M., and B. Lynn Johnston. "The Role of the Aceullular Pertussis Vaccine and the Comeback of 'Pertussis Pete'?" Canadian Journal of Infectious Diseases 12, no. 1 (2001): 15–17. http://dx.doi.org/10.1155/2001/839183.

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Pertussis or whooping cough is an acute infectious disease of the respiratory tract caused principally byBordetella pertussisand less commonly byBordetella parapertussis(1). Until two decades ago, pertussis in adults was a medical curiosity (2-4), but with the purification of specificBordetellaspecies antigens, the development of reliable enzyme immunoassays allowing accurate serological diagnosis and better understanding of the duration of immunity from vaccination, it has been clearly demonstrated thatB pertussisis a common cause of prolonged cough in adults. Indeed, its incidence has been i
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7

Pascual, F. Brian, Candace L. McCall, Aaron McMurtray, Tony Payton, Forrest Smith, and Kristine M. Bisgard. "Outbreak of Pertussis Among Healthcare Workers in a Hospital Surgical Unit." Infection Control & Hospital Epidemiology 27, no. 6 (2006): 546–52. http://dx.doi.org/10.1086/506232.

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Background.In September 1999, a pertussis outbreak was detected among surgical staff of a 138-bed community hospital. Patients were exposed toBordetella pertussisduring the 3-month outbreak period.Objective.To describe the outbreak among surgical staff, to evaluate implemented control measures, and to determine whether nosocomial transmission occurred.Methods.Clinical pertussis was defined as acute cough illness with a duration of 14 days or more without another apparent cause; persons with positive culture, PCR, or serologic test results were defined as having laboratory-confirmed pertussis.
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8

Daniels, Heather L., and Camille Sabella. "Bordetella pertussis (Pertussis)." Pediatrics in Review 39, no. 5 (2018): 247–57. http://dx.doi.org/10.1542/pir.2017-0229.

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9

Kandola, Kami, Amy Lea, Wanda White, and Maria Santos. "A Comparison of Pertussis Rates in the Northwest Territories: Pre- and Postacellular Pertussis Vaccine Introduction in Children and Adolescents." Canadian Journal of Infectious Diseases and Medical Microbiology 16, no. 5 (2005): 271–74. http://dx.doi.org/10.1155/2005/642315.

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INTRODUCTION: During the past decade, a trend toward increasing cases ofBordetella pertussisin older children and adults has been witnessed in Canada. The National Advisory Committee on Immunization now recommends that the adult formulation of the acellular pertussis (adult dTap) vaccine combined with diphtheria and tetanus toxoids be substituted for diphtheria and tetanus toxoids alone for the 14- to 16-year-old booster dose. In October 2000, the government of the Northwest Territories was one of the first to adopt adult dTap into their territorial immunization program free of charge.OBJECTIV
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10

Zhang, Xuqing, Sara E. Hester, Mary J. Kennett, et al. "Interleukin-1 Receptor Signaling Is Required To Overcome the Effects of Pertussis Toxin and for Efficient Infection- or Vaccination-Induced Immunity againstBordetella pertussis." Infection and Immunity 79, no. 1 (2010): 527–41. http://dx.doi.org/10.1128/iai.00590-10.

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ABSTRACTInterleukin-1 receptor-deficient (IL-1R−/−) mice are healthy despite being colonized by commensal microbes but are defective in defenses against specific pathogens, suggesting that IL-1R-mediated effects contribute to immune responses against specific pathogenic mechanisms. To better define the role of IL-1R in immunity to respiratory infections, we challenged IL-1R−/−mice withBordetella pertussisandBordetella parapertussis, the causative agents of whooping cough. Following inoculation withB. pertussis, but notB. parapertussis, IL-1R−/−mice showed elevated bacterial numbers and more ex
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11

Aase, Audun, Tove Karin Herstad, Samuel Merino, et al. "Immunization of Teenagers with a Fifth Dose of Reduced DTaP-IPV Induces High Levels of Pertussis Antibodies with a Significant Increase in Opsonophagocytic Activity." Clinical and Vaccine Immunology 18, no. 8 (2011): 1269–74. http://dx.doi.org/10.1128/cvi.05067-11.

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ABSTRACTWaning vaccine-induced immunity againstBordetella pertussisis observed among adolescents and adults. A high incidence of pertussis has been reported in this population, which serves as a reservoir forB. pertussis. A fifth dose of reduced antigen of diphtheria-tetanus-acellular-pertussis and inactivated polio vaccine was given as a booster dose to healthy teenagers. The antibody activity againstB. pertussisantigens was measured prior to and 4 to 8 weeks after the booster by different assays: enzyme-linked immunosorbent assays (ELISAs) of IgG and IgA against pertussis toxin (PT) and fila
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12

Pichichero, Michael E. "Pertussis and the pertussis vaccines." Current Opinion in Infectious Diseases 6, no. 4 (1993): 558–64. http://dx.doi.org/10.1097/00001432-199308000-00013.

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13

Handayani, Sarwo. "Profil Kekebalan Terhadap Difteri, Pertusis dan Tetanus pada Anak Umur di Bawah Lima Tahun, Hasil Riskesdas 2013." Buletin Penelitian Kesehatan 47, no. 3 (2019): 183–90. http://dx.doi.org/10.22435/bpk.v47i3.1503.

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Children under five years are a vulnerable group for diseases infection, therefore immunity to vaccine preventable diseases are essential, such as diphtheria, pertussis and tetanus. Those mentioned diseases, immunization is the most effective effort to reduce the mortality and morbidity. As a part of Basic Health Research analysis for samples collected in 2013, sera of 368 children under five years (aged 12-59 months) were tested for IgG to diphtheria, pertussis toxin and tetanus by ELISA method. The proportion of protective antibody associated with DPT immunization status obtained by univaria
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14

Fadugba, Olajumoke O., Li Wang, Qingxia Chen, and Natasha B. Halasa. "Immune Responses to Pertussis Antigens in Infants and Toddlers after Immunization with Multicomponent Acellular Pertussis Vaccine." Clinical and Vaccine Immunology 21, no. 12 (2014): 1613–19. http://dx.doi.org/10.1128/cvi.00438-14.

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ABSTRACTGiven the resurgence of pertussis despite high rates of vaccination with the diphtheria-tetanus-acellular pertussis (DTaP) vaccine, a better understanding of vaccine-induced immune responses toBordetella pertussisis needed. We investigated the antibody, cell-mediated, and cytokine responses toB. pertussisantigens in children who received the primary vaccination series (at 2, 4, and 6 months) and first booster vaccination (at 15 to 18 months) with 5-component acellular pertussis (aP) vaccine. The majority of subjects demonstrated a 4-fold increase in antibody titer to all four pertussis
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15

Burnett, Mark W. "Pertussis." Journal of Special Operations Medicine 13, no. 4 (2013): 113. http://dx.doi.org/10.55460/nb14-jh4h.

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16

Ang, Brenda. "Pertussis." Singapore Family Physician 45, no. 4 (2019): 15–17. http://dx.doi.org/10.33591/sfp.45.4.u3.

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17

Tompkins, Olga S. "Pertussis." AAOHN Journal 59, no. 6 (2011): 276. http://dx.doi.org/10.3928/08910162-20110525-04.

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18

Galiza, Eva P., Anna Calvert, Simon B. Drysdale, and Paul T. Heath. "Pertussis." Medicine 49, no. 12 (2021): 739–42. http://dx.doi.org/10.1016/j.mpmed.2021.09.002.

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19

Saks, Mark. "Pertussis." Emergency Medicine News 28, no. 6 (2006): 13–14. http://dx.doi.org/10.1097/00132981-200606000-00014.

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20

Liese, J. "Pertussis." Kinder- und Jugendmedizin 11, no. 03 (2011): 144–46. http://dx.doi.org/10.1055/s-0038-1629134.

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ZusammenfassungPertussis, die häufigste Form des Keuchhus-tens, ist eine Infektionskrankheit des Respirationstraktes, die durch Bordetella pertussis verursacht wird. In ungeimpften Populationen tritt Pertussis überwiegend im Alter zwischen zwei und sechs Jahren auf. In Populationen mit einer hohen Pertussis-Durchimpfungsrate im Kindesalter wird eine Verschiebung von Pertussiserkrankungen in das Adoleszentenund Erwachsenenalter beobachtet. Dadurch entstehen neue Übertragungswege auf junge, oft ungeimpfte Säuglinge. Diese wiederum haben das höchste Risiko für einen schweren Verlauf der Pertussis
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21

Chiocca, Ellen M. "Pertussis." Nursing 36, no. 7 (2006): 72. http://dx.doi.org/10.1097/00152193-200607000-00051.

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22

Heath, Paul T., and Louise A. Denvir. "Pertussis." Medicine 29, no. 3 (2001): 91–93. http://dx.doi.org/10.1383/medc.29.3.91.27599.

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23

Sinha, Ruchi, and Paul T. Heath. "Pertussis." Medicine 33, no. 5 (2005): 101–2. http://dx.doi.org/10.1383/medc.33.5.101.64962.

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24

Andersen, Erin. "Pertussis." AAOHN Journal 52, no. 12 (2004): 498–99. http://dx.doi.org/10.1177/216507990405201202.

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25

Olga, S. Tompkins. "Pertussis." AAOHN Journal 59, no. 6 (2011): 276. http://dx.doi.org/10.1177/216507991105900606.

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26

Heininger, Ulrich. "Pertussis." Pediatric Infectious Disease Journal 31, no. 1 (2012): 78–79. http://dx.doi.org/10.1097/inf.0b013e31823b034e.

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27

Galiza, Eva P., and Paul T. Heath. "Pertussis." Medicine 37, no. 12 (2009): 635–37. http://dx.doi.org/10.1016/j.mpmed.2009.09.007.

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28

Kent, Alison, and Paul T. Heath. "Pertussis." Medicine 42, no. 1 (2014): 8–10. http://dx.doi.org/10.1016/j.mpmed.2013.10.007.

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29

Calvert, Anna, and Paul T. Heath. "Pertussis." Medicine 45, no. 12 (2017): 735–38. http://dx.doi.org/10.1016/j.mpmed.2017.09.015.

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30

Nguyen, Van Tuong Ngoc, and Lauren Simon. "Pertussis." Primary Care: Clinics in Office Practice 45, no. 3 (2018): 423–31. http://dx.doi.org/10.1016/j.pop.2018.05.003.

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31

Schweon, Steven J. "Pertussis." Nursing 41, no. 10 (2011): 61–62. http://dx.doi.org/10.1097/01.nurse.0000405118.16392.86.

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32

Spector, Tara B., and Eileen K. Maziarz. "Pertussis." Medical Clinics of North America 97, no. 4 (2013): 537–52. http://dx.doi.org/10.1016/j.mcna.2013.02.004.

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33

Leber, Amy L. "Pertussis." Clinics in Laboratory Medicine 34, no. 2 (2014): 237–55. http://dx.doi.org/10.1016/j.cll.2014.02.003.

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34

Weisberg, Susan Shoshana. "Pertussis." Disease-a-Month 53, no. 10 (2007): 488–94. http://dx.doi.org/10.1016/j.disamonth.2007.09.012.

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35

Weinstein, Robert. "Pertussis." Infection Control & Hospital Epidemiology 11, no. 5 (1990): 268. http://dx.doi.org/10.1017/s0899823x00083148.

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36

Gabutti, Giovanni, Chiara Azzari, Paolo Bonanni, et al. "Pertussis." Human Vaccines & Immunotherapeutics 11, no. 1 (2014): 108–17. http://dx.doi.org/10.4161/hv.34364.

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37

Jakinovich, Andrea, and Sunil K. Sood. "Pertussis." Current Opinion in Pediatrics 26, no. 5 (2014): 597–604. http://dx.doi.org/10.1097/mop.0000000000000139.

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38

Kadin, M. "Pertussis." ASH Image Bank 2003, no. 0507 (2003): 100701. http://dx.doi.org/10.1182/ashimagebank-2003-100701.

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39

Lazarchick, J. "Pertussis." ASH Image Bank 2005, no. 0325 (2005): 101340. http://dx.doi.org/10.1182/ashimagebank-2005-101340.

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40

MATHIS, ROBERT D., BARBARA SHOAF, and TRACY I. WEINER. "Pertussis." Pediatric Emergency Care 9, no. 4 (1993): 218–20. http://dx.doi.org/10.1097/00006565-199308000-00010.

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41

Heininger, U. "Pertussis." Monatsschrift Kinderheilkunde 164, no. 11 (2016): 987–93. http://dx.doi.org/10.1007/s00112-016-0158-z.

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42

Plotkin, Stanley A. "Pertussis." Vaccine 7, no. 3 (1989): 195. http://dx.doi.org/10.1016/0264-410x(89)90227-2.

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43

Pluta, Ryszard M. "Pertussis." JAMA 304, no. 8 (2010): 922. http://dx.doi.org/10.1001/jama.304.8.922.

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44

Hildebrand, Erin. "Pertussis." Nursing 55, no. 5 (2025): 12–14. https://doi.org/10.1097/nsg.0000000000000190.

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45

Guiso, N., and D. Hozbor. "Bordetella pertussis Polymorphism and Pertussis Vaccines." Clinical and Vaccine Immunology 15, no. 2 (2008): 394–95. http://dx.doi.org/10.1128/cvi.00391-07.

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46

Hong, Jung Yun. "Update on pertussis and pertussis immunization." Korean Journal of Pediatrics 53, no. 5 (2010): 629. http://dx.doi.org/10.3345/kjp.2010.53.5.629.

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47

Herwaldt, Lorween A. "Pertussis and Pertussis Vaccines in Adults." JAMA: The Journal of the American Medical Association 269, no. 1 (1993): 93. http://dx.doi.org/10.1001/jama.1993.03500010103042.

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48

Herwaldt, L. A. "Pertussis and pertussis vaccines in adults." JAMA: The Journal of the American Medical Association 269, no. 1 (1993): 93–94. http://dx.doi.org/10.1001/jama.269.1.93.

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49

Hanawa, Tomoko, Kazunari Kamachi, Hideo Yonezawa, Toshiyuki Fukutomi, Hayato Kawakami, and Shigeru Kamiya. "Glutamate Limitation, BvgAS Activation, and (p)ppGpp Regulate the Expression of the Bordetella pertussis Type 3 Secretion System." Journal of Bacteriology 198, no. 2 (2015): 343–51. http://dx.doi.org/10.1128/jb.00596-15.

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ABSTRACTBordetella pertussisis a bacterium that is considered to be highly adapted to humans, and it has not been isolated from the environment. As this bacterium does not utilize sugars, the abundant supply of glutamate in Stainer Scholte (SS) medium enablesB. pertussisto grow efficiently in liquid culturein vitro, and as such, SS medium is a popular choice for laboratory experiments. However, the concentration of glutamate in thein vivoniche ofB. pertussisis quite low. We investigated the bacterial response to low concentrations of glutamate to elucidate bacterial physiology via the expressi
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50

Burgos-Rivera, Brunilís, Adria D. Lee, Katherine E. Bowden, et al. "Evaluation of Level of Agreement in Bordetella Species Identification in Three U.S. Laboratories during a Period of Increased Pertussis." Journal of Clinical Microbiology 53, no. 6 (2015): 1842–47. http://dx.doi.org/10.1128/jcm.03567-14.

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While PCR is the most common method used for detectingBordetella pertussisin the United States, most laboratories use insertion sequence481(IS481), which is not specific forB. pertussis; therefore, the relative contribution of otherBordetellaspecies is not understood. The objectives of this study were to evaluate the proportion of otherBordetellaspecies misidentified asB. pertussisduring a period of increased pertussis incidence, determine the level of agreement inBordetellaspecies detection between U.S. commercial laboratories and the CDC, and assess the relative diagnostic sensitivity of CDC
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