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Journal articles on the topic 'PET imaging data'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Izquierdo-Garcia, David, and Ciprian Catana. "MR Imaging–Guided Attenuation Correction of PET Data in PET/MR Imaging." PET Clinics 11, no. 2 (2016): 129–49. http://dx.doi.org/10.1016/j.cpet.2015.10.002.

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Erlandsson, Kjell, John Dickson, Simon Arridge, David Atkinson, Sebastien Ourselin, and Brian F. Hutton. "MR Imaging–Guided Partial Volume Correction of PET Data in PET/MR Imaging." PET Clinics 11, no. 2 (2016): 161–77. http://dx.doi.org/10.1016/j.cpet.2015.09.002.

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Muzi, Mark, Finbarr O'Sullivan, David A. Mankoff, et al. "Quantitative assessment of dynamic PET imaging data in cancer imaging." Magnetic Resonance Imaging 30, no. 9 (2012): 1203–15. http://dx.doi.org/10.1016/j.mri.2012.05.008.

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Lassen, Martin Lyngby, Thomas Beyer, Alexander Berger, et al. "Data-driven, projection-based respiratory motion compensation of PET data for cardiac PET/CT and PET/MR imaging." Journal of Nuclear Cardiology 27, no. 6 (2019): 2216–30. http://dx.doi.org/10.1007/s12350-019-01613-2.

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Mazoyer, Bernard M., Ronald H. Huesman, Thomas F. Budinger, and Brian L. Knittel. "Dynamic PET Data Analysis." Journal of Computer Assisted Tomography 10, no. 4 (1986): 645–53. http://dx.doi.org/10.1097/00004728-198607000-00020.

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Guo, Hongbin, Rosemary Renaut, Kewei Chen, and Eric Reiman. "Clustering huge data sets for parametric PET imaging." Biosystems 71, no. 1-2 (2003): 81–92. http://dx.doi.org/10.1016/s0303-2647(03)00112-6.

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Thorwarth, Daniela, Linda-Jacqueline Wack, and David Mönnich. "Hypoxia PET imaging techniques: data acquisition and analysis." Clinical and Translational Imaging 5, no. 6 (2017): 489–96. http://dx.doi.org/10.1007/s40336-017-0250-y.

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Rapoport, Stanley I. "Discriminant Analysis of Brain Imaging Data Identifies Subjects With Early Alzheimer's Disease." International Psychogeriatrics 9, S1 (1997): 229–35. http://dx.doi.org/10.1017/s1041610297004936.

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In vivo functional brain imaging provides an opportunity to quantify and localize functional deficits associated with Alzheimer's disease (AD), in relation to dementia severity and heterogeneous cognitive profiles. Such imaging also provides a basis for distinguishing AD from other causes of dementia and for making an early diagnosis of disease. One imaging modality that can elucidate AD is positron emission tomography (PET), which is used to measure regional cerebral metabolic rates for glucose (rCMRglc) and regional cerebral blood flow (rCBF). Resting-state measurements with PET, when relate

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Kwee, Thomas C., Robert M. Kwee, and Rutger A. J. Nievelstein. "Imaging in staging of malignant lymphoma: a systematic review." Blood 111, no. 2 (2008): 504–16. http://dx.doi.org/10.1182/blood-2007-07-101899.

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Computed tomography (CT) is currently the most commonly used means for staging malignant lymphoma. 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET), FDG-PET/CT fusion, and whole-body magnetic resonance imaging (WB-MRI) are potential alternatives. The purpose of this study was to systematically review published data on the diagnostic performance of CT, FDG-PET, FDG-PET/CT fusion, and WB-MRI in staging of malignant lymphoma. In addition, technical aspects, procedures, advantages, and drawbacks of each imaging modality are outlined. Three CT studies, 17 FDG-PET studies, and 4 FDG-

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Schuler, Markus K., Stephan Richter, Bettina Beuthien-Baumann, et al. "PET/MRI Imaging in High-Risk Sarcoma: First Findings and Solving Clinical Problems." Case Reports in Oncological Medicine 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/793927.

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Simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) is a new whole-body hybrid PET/MR imaging technique that combines metabolic and cross-sectional diagnostic imaging. Since the use of MRI in imaging of soft-tissue sarcoma is extremely beneficial, investigation of the combined PET/MRI is of great interest. In this paper, we present three cases and first data. Combined PET/MRI technique can support the process of clinical decision-making and give answers to some meaningful questions when treating patients with STS. Therefore, the combined modality of simultaneou

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Hu, Yang Sheng, Jun Zhang, Rui Cui, et al. "An Initial Study for PET Imaging Simulation." Applied Mechanics and Materials 513-517 (February 2014): 612–15. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.612.

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Simulation play an important role in the research of PET/CT imaging technology. In this paper, GATE (Geant4 Application Tomography Emission) software packages and NCAT(dynamic NURBS-based cardiac-torso phantom) were used to simulate GE ST PET/CT imaging. GATE provides abundant of functions to simulate both PET/CT imaging procedure and geometric phantom generation. NCAT can generate voxlised body torso phantom. Three different kinds of digital phantoms were designed and generated for PET/CT imaging simulation. The simulation output of GATE was converted to the data format that the STIR (Softwar

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Mannheim, Julia G., Martin Mamach, Sybille Reder, et al. "Reproducibility and Comparability of Preclinical PET Imaging Data: A Multicenter Small-Animal PET Study." Journal of Nuclear Medicine 60, no. 10 (2019): 1483–91. http://dx.doi.org/10.2967/jnumed.118.221994.

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Shidahara, Miho, Yoko Ikoma, Jeff Kershaw, Yuichi Kimura, Mika Naganawa, and Hiroshi Watabe. "PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging." Annals of Nuclear Medicine 21, no. 7 (2007): 379–86. http://dx.doi.org/10.1007/s12149-007-0044-9.

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Massager, Nicolas, Philippe David, Serge Goldman, et al. "Combined MRI and PET imaging in brain stem mass lesions: diagnostic yield in a series of 30 stereotactically biopsied patients." Journal of Neurosurgery 93, no. 6 (2000): 951–57. http://dx.doi.org/10.3171/jns.2000.93.6.0951.

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Object. In the management of brainstem lesions, the place of stereotactic biopsy sampling remains debatable. The authors compared the results of magnetic resonance (MR) imaging, positron emission tomography (PET) scanning, and histological studies obtained in 30 patients who underwent MR imaging— and PET-guided stereotactic biopsy procedures for a brainstem mass lesion.Methods. Between July 1991 and December 1998, 30 patients harboring brainstem mass lesions underwent a stereotactic procedure in which combined MR imaging and PET scanning guidance were used. Positron emission tomography scannin

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Manabe, Osamu, Noriko Oyama-Manabe, and Nagara Tamaki. "Positron emission tomography/MRI for cardiac diseases assessment." British Journal of Radiology 93, no. 1113 (2020): 20190836. http://dx.doi.org/10.1259/bjr.20190836.

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Functional imaging tools have emerged in the last few decades and are increasingly used to assess the function of the human heart in vivo. Positron emission tomography (PET) is used to evaluate myocardial metabolism and blood flow. Magnetic resonance imaging (MRI) is an essential tool for morphological and functional evaluation of the heart. In cardiology, PET is successfully combined with CT for hybrid cardiac imaging. The effective integration of two imaging modalities allows simultaneous data acquisition combining functional, structural and molecular imaging. After PET/CT has been successfu

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Mayer, Dmitri, and Edward M. Bednarczyk. "Interaction of Colony-Stimulating Factors and Fluorodeoxyglucose F18 Positron Emission Tomography." Annals of Pharmacotherapy 36, no. 11 (2002): 1796–99. http://dx.doi.org/10.1345/aph.1c072.

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OBJECTIVE: To evaluate reports of altered diagnostic images with fluorodeoxyglucose F18 (FDG) positron emission tomography (PET) after treatment with colony-stimulating factors (CSFs). DATA SOURCES: Literature was identified by a MEDLINE search (1966–December 2001). Key search terms included granulocyte colony-stimulating factor, granulocyte—macrophage colony-stimulating factor, macrophage colony-stimulating factor, fluorodeoxyglucose, and emission-computed tomography. English language literature was reviewed. DATA SYNTHESIS: Reports have suggested altered FDG PET images following CSF treatmen

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Hersh, Marla R., Junsung Choi, Chris Garrett, and Robert Clark. "Imaging Gastrointestinal Stromal Tumors." Cancer Control 12, no. 2 (2005): 111–15. http://dx.doi.org/10.1177/107327480501200206.

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Background: Because of the recent reclassification of mesenchymal tumors, which was based on a better understanding of the genetics and immunophenotype of gastrointestinal stromal tumors (GISTs), only a limited number of studies have described the radiologic appearance of GISTs. Methods: This study reviews the imaging characteristics of GISTs, with an emphasis on differentiating benign and malignant tumors using positron emission tomography (PET), computed tomography (CT), and magnetic resonance imaging (MRI). We reviewed the data from 53 cases of GISTs treated at our institute. The imaging st

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Torrado-Carvajal, A., L. García-Cañamaque, and N. Malpica. "Teaching a hands-on session on simultaneous Positron Emission Tomography and Magnetic Resonance image acquisition and quantification in a clinical setting." Journal of Instrumentation 19, no. 04 (2024): C04028. http://dx.doi.org/10.1088/1748-0221/19/04/c04028.

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Abstract Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging, is a novel imaging modality that combines the capabilities of two powerful imaging techniques in a single acquisition. This unique integration allows for simultaneous acquisition of both metabolic and structural data within a single imaging session. In this sense, PET/MR offers a comprehensive and innovative approach to medical imaging, but accompanied by its intrinsic physics and engineering complexity, involving intricate synchronization of high-performance detectors, electromagnetic shielding, and sophisticated corre

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Xiang, Lili, Chuanhua Yang, Wenneng Liu, Dong Li, Zongze Jiang, and Huijun Zhou. "Clinical Value of PET.CT Based on Big Data in Colorectal and Peritoneal Metastatic Cancer." Contrast Media & Molecular Imaging 2022 (September 30, 2022): 1–7. http://dx.doi.org/10.1155/2022/6120337.

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This study focuses on the evaluation of the clinical utility of PET-CT imaging in peritoneal metastases and colorectal cancer. One hundred patients with colorectal peritoneal metastases, who underwent whole-body PET-CT imaging from January 2015 to December 2019, were selected as the experimental group, and 20 healthy individuals were selected as the control group. The SUVmax of the two groups of patients was 5.73 ± 3.84 and 2.70 ± 2.32, respectively, and the difference was statistically significant. The SUVmax AUC was 0.720, and the AUC of serum AFP, CEA, CA125, and CA199 were 0.596, 0.677, 0.

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Štokelj, Eva, and Urban Simončič. "Data-Driven Image-Based Protocol for Brain PET Image Harmonization." Sensors 25, no. 13 (2025): 4230. https://doi.org/10.3390/s25134230.

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Quantitative FDG-PET brain imaging across multiple centers is challenged by inter-scanner variability, impacting the comparability of neuroimaging data. This study proposes a data-driven image-based harmonization protocol to address these discrepancies without relying on traditional phantom scans. The protocol uses spatially normalized FDG-PET brain images to estimate scanner-specific Gaussian smoothing filters, optimizing parameters via the structural similarity index (SSIM). Validation was performed using images from cognitively normal individuals and Alzheimer’s disease patients from the Al

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Weisbrod, Allison B., Mio Kitano, Krisana Gesuwan, et al. "Clinical Utility of Functional Imaging with 18F-FDOPA in Von Hippel-Lindau Syndrome." Journal of Clinical Endocrinology & Metabolism 97, no. 4 (2012): E613—E617. http://dx.doi.org/10.1210/jc.2011-2626.

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Context: Von Hippel-Lindau (VHL) syndrome is an inherited cancer syndrome in which patients are at risk of developing multiple tumors in different organs. 6-L-18F-fluorodihydroxyphenylalanine (18F-FDOPA) positron emission tomography (PET) is a relatively new metabolic imaging tracer proposed for the use of localizing sites of neuroendocrine tumors. There are limited data on the clinical utility of using 18F-FDOPA PET for identifying neuroendocrine tumors in a high-risk population such as VHL. Objective: The aim of this prospective study was to evaluate the clinical utility of 18F-FDOPA PET in

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Yildiz, Halil, Charlotte Lepere, Giulia Zorzi, Olivier Gheysens, Fabien Roodhans, and Lucie Pothen. "[18F]FDG-PET/CT in Idiopathic Inflammatory Myopathies: Retrospective Data from a Belgian Cohort." Diagnostics 13, no. 14 (2023): 2316. http://dx.doi.org/10.3390/diagnostics13142316.

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[18F]FDG-PET/CT is a useful tool for diagnosis and cancer detection in idiopathic inflammatory myopathies (IIMs), especially polymyositis (PM) and dermatomyositis (DM). Data deriving from Europe are lacking. We describe [18F]FDG-PET/CT results in a Belgian cohort with IIMs, focusing on patients with PM and DM. All of the cases of IIMs admitted between December 2010 and January 2023 to the Cliniques Universitaires Saint-Luc (Belgium) were retrospectively reviewed. In total, 44 patients were identified with suspected IIMs; among them, 29 were retained for final analysis. The mean age of the reta

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Weber, Wolfgang A. "Positron Emission Tomography As an Imaging Biomarker." Journal of Clinical Oncology 24, no. 20 (2006): 3282–92. http://dx.doi.org/10.1200/jco.2006.06.6068.

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Positron emission tomography (PET) allows noninvasive, quantitative studies of various biologic processes in the tumor tissue. By using PET, investigators can study the pharmacokinetics of anticancer drugs, identify various therapeutic targets and monitor the inhibition of these targets during therapy. Furthermore, PET provides various markers to assess tumor response early in the course of therapy. A significant number of studies have now shown that changes in tumor glucose utilization during the first weeks of chemotherapy are significantly correlated with patient outcome. These data suggest

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Beyer, T., and G. Brix. "PET/CT." Nuklearmedizin 44, S 01 (2005): S51—S57. http://dx.doi.org/10.1055/s-0038-1625216.

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Summary:Clinical studies demonstrate a gain in diagnostic accuracy by employing combined PET/CT instead of separate CT and PET imaging. However, whole-body PET/CT examinations result in a comparatively high radiation burden to patients and thus require a proper justification and optimization to avoid repeated exposure or over-exposure of patients. This review article summarizes relevant data concerning radiation exposure of patients resulting from the different components of a combined PET/CT examination and presents different imaging strategies that can help to balance the diagnostic needs an

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Sander, Christin Y., Hanne D. Hansen, and Hsiao-Ying Wey. "Advances in simultaneous PET/MR for imaging neuroreceptor function." Journal of Cerebral Blood Flow & Metabolism 40, no. 6 (2020): 1148–66. http://dx.doi.org/10.1177/0271678x20910038.

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Hybrid imaging using PET/MRI has emerged as a platform for elucidating novel neurobiology, molecular and functional changes in disease, and responses to physiological or pharmacological interventions. For the central nervous system, PET/MRI has provided insights into biochemical processes, linking selective molecular targets and distributed brain function. This review highlights several examples that leverage the strengths of simultaneous PET/MRI, which includes measuring the perturbation of multi-modal imaging signals on dynamic timescales during pharmacological challenges, physiological inte

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Tamijeselvan, S. "Applications of PET/MRI in prostate cancer." Annals of Geriatric Education and Medical Sciences 10, no. 2 (2024): 55–59. http://dx.doi.org/10.18231/j.agems.2023.013.

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The advantages of both PET and MRI are combined with PET/MRI to provide near-perfect picture co-registration and simultaneous image capture. Prostate cancer and other pelvic oncologic lesions are increasingly being staged and restaged using magnetic resonance imaging (MRI). Long regarded as the cornerstone of oncologic imaging, fluorine 18-fluorodeoxyglucose PET/CT is now being studied and used in clinical practice more often due to the emergence of several tailored radiotracers. Therefore, PET/MRI performed concurrently offers a number of advantages over PET/CT and MR image collections, inclu

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Chandrasekaran, Sanjay, Andrew Hollander, Xiangsheng Xu, et al. "18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns." Scientific World Journal 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/796029.

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Introduction. PET imaging is a useful clinical tool for studying tumor progression and treatment effects. Conventional18F-FDG-PET imaging is of limited usefulness for imaging Glioblastoma Multiforme (GBM) due to high levels of glucose uptake by normal brain and the resultant signal-to-noise intensity.18F-Fluorothymidine (FLT) in contrast has shown promise for imaging GBM, as thymidine is taken up preferentially by proliferating cells. These studies were undertaken to investigate the effectiveness of18F-FLT-PET in a GBM mouse model, especially after radiation therapy (RT), and its correlation w

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Shetty, Dinesh, Jae-Min Jeong, and Hyunsuk Shim. "Stroma Targeting Nuclear Imaging and Radiopharmaceuticals." International Journal of Molecular Imaging 2012 (May 21, 2012): 1–23. http://dx.doi.org/10.1155/2012/817682.

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Malignant transformation of tumor accompanies profound changes in the normal neighboring tissue, called tumor stroma. The tumor stroma provides an environment favoring local tumor growth, invasion, and metastatic spreading. Nuclear imaging (PET/SPECT) measures biochemical and physiologic functions in the human body. In oncology, PET/SPECT is particularly useful for differentiating tumors from postsurgical changes or radiation necrosis, distinguishing benign from malignant lesions, identifying the optimal site for biopsy, staging cancers, and monitoring the response to therapy. Indeed, PET/SPEC

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Alanazi, Maram Mohammed Fawaz. "Advancements in hybrid imaging techniques: Enhancing diagnostic accuracy with PET/MRI and PET/CT." International journal of health sciences 8, S1 (2024): 1800–1811. https://doi.org/10.53730/ijhs.v8ns1.15396.

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Background Hybrid imaging techniques, including PET/MRI and PET/CT, are transforming medical diagnostics by integrating metabolic data from Positron Emission Tomography (PET) with the detailed anatomical resolution provided by Magnetic Resonance Imaging (MRI) or Computed Tomography (CT). This integration improves diagnostic accuracy, especially in oncology, where accurate tumor localization and characterization are essential for effective treatment planning. PET/CT is commonly utilized; however, PET/MRI presents benefits including enhanced soft tissue contrast and decreased radiation exposure,

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Kim, Sung-Yong, Hyun Woo Chung, Young So, Mark Hong Lee, and Eun Jeong Lee. "Recent Updates of PET in Lymphoma: FDG and Beyond." Biomedicines 12, no. 11 (2024): 2485. http://dx.doi.org/10.3390/biomedicines12112485.

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Lymphoma is one of the most common cancers worldwide, categorized into Hodgkin lymphoma and non-Hodgkin lymphoma. 18F-fluorodeoxyglucose positron emission tomography (FDG PET) has become an essential imaging tool for evaluating patients with lymphoma in terms of initial diagnosis, staging, prognosis, and treatment response assessment. Recent advancements in imaging technology and methodologies, along with the development of artificial intelligence, have revolutionized the evaluation of complex imaging data, enhancing the diagnostic and predictive power of PET in lymphoma. However, FDG is not c

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Kubik, Agata, Anna Budzyńska, Krzysztof Kacperski, et al. "Evaluation of qualitative and quantitative data of Y-90 imaging in SPECT/CT and PET/CT phantom studies." PLOS ONE 16, no. 2 (2021): e0246848. http://dx.doi.org/10.1371/journal.pone.0246848.

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Introduction We aimed to assess the feasibility of SPECT and PET Y-90 imaging, and to compare these modalities by visualizing hot and cold foci in phantoms for varying isotope concentrations. Materials and methods The data was acquired from the Jaszczak and NEMA phantoms. In the Jaszczak phantom Y-90 concentrations of 0.1 MBq/ml and 0.2 MBq/ml were used, while higher concentrations, up to 1.0 MBq/ml, were simulated by acquisition time extension with respect to the standard clinical protocol of 30 sec/projection for SPECT and 30 min/bed position for PET imaging. For NEMA phantom, the hot foci h

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Massager, Nicolas, Philippe David, Serge Goldman, et al. "Combined magnetic resonance imaging– and positron emission tomography–guided stereotactic biopsy in brainstem mass lesions: diagnostic yield in a series of 30 patients." Neurosurgical Focus 8, no. 2 (2000): 1–6. http://dx.doi.org/10.3171/foc.2000.8.2.2.

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In the management of brainstem lesions, the place of stereotactic biopsy sampling remains debatable. The authors compared the results of magnetic resonance (MR) imaging, positron emission tomography (PET), and histological findings obtained in 30 patients who underwent an MR image– and PET-guided stereotactic biopsy procedure for a brainstem mass lesion. Between July 1991 and December 1998, 30 patients harboring a brainstem mass lesion underwent a stereotactic procedure in which combined MR imaging and PET guidance was used. Positron emission tomography scanning was performed using [18F]-fluor

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Goh, A. S. W., and D. C. E. Ng. "Clinical Positron Emission Tomography Imaging—Current Applications." Annals of the Academy of Medicine, Singapore 32, no. 4 (2003): 507–17. http://dx.doi.org/10.47102/annals-acadmedsg.v32n4p507.

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Positron emission tomography (PET) is an established imaging technique based on the use of short-lived radiotracers. The unique value of PET lies in the ability of various radiochemical compounds to serve as tracers for measuring specific metabolic processes in the body. This enables detection of the early biochemical anomalies that precede the structural changes seen on other imaging techniques. For decades, PET had remained essentially a research tool in academic institutions. However, in recent years, it has emerged as a vital clinical tool, particularly for cancer diagnosis and management.

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Pirotte, Benoit J. M., Alphonse Lubansu, Nicolas Massager, et al. "Clinical interest of integrating positron emission tomography imaging in the workup of 55 children with incidentally diagnosed brain lesions." Journal of Neurosurgery: Pediatrics 5, no. 5 (2010): 479–85. http://dx.doi.org/10.3171/2010.1.peds08336.

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Object In this paper, the authors' goal was to evaluate the impact of PET data on the clinical management of incidental brain lesions in children. Methods Between 1995 and 2007, 442 children with a newly diagnosed brain lesion were referred to the authors' department. Of these, 55 presented with an incidental brain lesion and were selected for study because MR imaging sequences revealed limitations in assessing the tumor, its evolving nature, and/or the malignant potential of the lesion diagnosed. Thirteen children were studied using FDG-PET and 42 with L-(methyl-11C)-methionine (MET)–PET; 3 c

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Drake, Lindsey R., Ansel T. Hillmer, and Zhengxin Cai. "Approaches to PET Imaging of Glioblastoma." Molecules 25, no. 3 (2020): 568. http://dx.doi.org/10.3390/molecules25030568.

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Glioblastoma multiforme (GBM) is the deadliest type of brain tumor, affecting approximately three in 100,000 adults annually. Positron emission tomography (PET) imaging provides an important non-invasive method of measuring biochemically specific targets at GBM lesions. These powerful data can characterize tumors, predict treatment effectiveness, and monitor treatment. This review will discuss the PET imaging agents that have already been evaluated in GBM patients so far, and new imaging targets with promise for future use. Previously used PET imaging agents include the tracers for markers of

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Viswanath, Varsha, Rhea Chitalia, Austin R. Pantel, Joel S. Karp, and David A. Mankoff. "Analysis of Four-Dimensional Data for Total Body PET Imaging." PET Clinics 16, no. 1 (2021): 55–64. http://dx.doi.org/10.1016/j.cpet.2020.09.009.

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Scussolini, Mara, Sara Garbarino, Gianmario Sambuceti, Giacomo Caviglia, and Michele Piana. "A physiology-based parametric imaging method for FDG–PET data." Inverse Problems 33, no. 12 (2017): 125010. http://dx.doi.org/10.1088/1361-6420/aa9544.

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Kesner, Adam Leon. "Current state of data-based gating technology in PET imaging." European Journal of Nuclear Medicine and Molecular Imaging 38, no. 4 (2011): 785. http://dx.doi.org/10.1007/s00259-010-1722-8.

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Masselli, Gabriele, and Chiara Di Bella. "Will PET/MR Imaging Replace PET/CT for Pediatric Applications?" Diagnostics 15, no. 9 (2025): 1070. https://doi.org/10.3390/diagnostics15091070.

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The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) is a modern, highly advanced diagnostic tool that offers numerous advantages in the treatment and management of some pediatric pathologies. The use of PET/MR in children provides high-resolution images with outstanding tissue characterization, as well as important metabolic and physiological information; it is not only essential for early diagnosis, but also for the assessment and management of oncological, neurological, and cardiovascular diseases. The hybrid PET/MR is a multimodal approach that reduces

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Paone, G., F. Martucci, V. Espeli, et al. "18F-FDG-PET/CT Imaging in Advanced Glottic Cancer: A Tool for Clinical Decision in Comparison with Conventional Imaging." Contrast Media & Molecular Imaging 2019 (September 11, 2019): 1–12. http://dx.doi.org/10.1155/2019/4051206.

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This study assessed the role of 18F-FDG PET-CT (PET/CT) to detect the cartilage and paraglottic infiltration in advanced glottic cancer comparing the results with those of conventional imaging (CI) (contrast-enhanced computed tomography and/or magnetic resonance). In addition, we assessed the prognostic value of quantitative parameters, measured on baseline PET/CT, in terms of event-free survival (EFS) and overall survival (OS). We retrospectively analyzed 27 patients with glottic squamous cell carcinoma stage III and IVA, treated in our institute between 2010 and 2016, comparing PET/CT, perfo

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Fukumitsu, Nobuyoshi, and Yoshitaka Matsumoto. "Development of an Imaging Technique for Boron Neutron Capture Therapy." Cells 10, no. 8 (2021): 2135. http://dx.doi.org/10.3390/cells10082135.

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The development of 4-10B-borono-2-18F-fluoro-L-phenylalanine (18FBPA) for use in positron emission tomography (PET) has contributed to the progress of boron neutron capture therapy (BNCT). 18FBPA has shown similar pharmacokinetics and distribution to 4-10B-borono-L-phenylalanine (BPA) under various conditions in many animal studies. 18FBPA PET is useful for treatment indication. A higher 18FBPA accumulation ratio of the tumor to the surrounding normal tissue (T/N ratio) indicates that a superior treatment effect is expected. In clinical settings, a T/N ratio of higher than 2.5 or 3 is often us

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Krolak, C., S. Kessler, R. Tiling, and S. Höpfner. "Preoperative imaging of Charcot neuroarthropathy." Nuklearmedizin 45, no. 01 (2006): 15–20. http://dx.doi.org/10.1055/s-0038-1623931.

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SummaryWith about 4 million diabetics in germany and presumed inclination over the following years the treatment of diabetic complications like diabetic foot will become an even more important point. The management of Charcot’s foot has undergone fundamental change in the last few years. Formerly, treatment was almost exclusively limited to non surgical measures; since the late 1990’s, however, current practice has shifted to early, stage-appropriate surgical therapy. The aim of the present prospective study was to investigate the value of positron emission tomography (PET) in the pre-operativ

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Saerens, Julie, Brigitte Velkeniers, Marleen Keyaerts, et al. "Value of [11C]-Methionine PET/CT in Preoperative Localization of Parathyroid Adenomas." Hormone and Metabolic Research 53, no. 07 (2021): 444–52. http://dx.doi.org/10.1055/a-1475-4600.

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AbstractThere are multiple imaging modalities in primary hyperparathyroidism. Ultrasound examination and subtraction scintigraphy are usually the first-line imaging techniques. When these results are negative or inconsistent, additional [11C]-methionine PET/CT (MET-PET/CT) or 4-dimensional computed tomography can be performed. This study aims to evaluate MET-PET/CT in comparison with other imaging techniques in primary hyperparathyroidism. This is a retrospective cohort study. Eighty-four patients with primary hyperparathyroidism, who underwent parathyroid surgery, were included. Imaging res

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Kaplanoglu, Tevfik, and Paweł Moskal. "A cross-staged gantry for total-body PET and CT imaging." Bio-Algorithms and Med-Systems 19, no. 1 (2023): 109–13. http://dx.doi.org/10.5604/01.3001.0054.1941.

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Total-body Positron Emission Tomography (PET) scanning is a promising new method for rapidly acquiring comprehensive wide-volume metabolic data with a lower radiation dosage compared to discrete whole-body PET imaging. PET scanners are generally used with Computed Tomography (CT) scanners to precisely understand tumor location and composition with the help of anatomical images. However, PET/CT sequential imaging methods for simultaneous total-body imaging are impractical for claustrophobic patients due to the enclosed gantry design and require large examination rooms because of the need for an

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Thomas, M. Allan, Joseph G. Meier, Osama R. Mawlawi, Peng Sun, and Tinsu Pan. "Impact of acquisition time and misregistration with CT on data-driven gated PET." Physics in Medicine & Biology 67, no. 8 (2022): 085012. http://dx.doi.org/10.1088/1361-6560/ac5f73.

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Abstract Objective. Data-driven gating (DDG) can address patient motion issues and enhance PET quantification but suffers from increased image noise from utilization of <100% of PET data. Misregistration between DDG-PET and CT may also occur, altering the potential benefits of gating. Here, the effects of PET acquisition time and CT misregistration were assessed with a combined DDG-PET/DDG-CT technique. Approach. In the primary PET bed with lesions of interest and likely respiratory motion effects, PET acquisition time was extended to 12 min and a low-dose cine CT was acquired to enable DDG

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Hochhegger, Bruno, Giordano Rafael Tronco Alves, Klaus Loureiro Irion, et al. "PET/CT imaging in lung cancer: indications and findings." Jornal Brasileiro de Pneumologia 41, no. 3 (2015): 264–74. http://dx.doi.org/10.1590/s1806-37132015000004479.

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The use of PET/CT imaging in the work-up and management of patients with lung cancer has greatly increased in recent decades. The ability to combine functional and anatomical information has equipped PET/CT to look into various aspects of lung cancer, allowing more precise disease staging and providing useful data during the characterization of indeterminate pulmonary nodules. In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer. However, the i

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Henkel, Rebecca, Matthias Brendel, Marco Paolini, et al. "FDG PET Data is Associated with Cognitive Performance in Patients from a Memory Clinic." Journal of Alzheimer's Disease 78, no. 1 (2020): 207–16. http://dx.doi.org/10.3233/jad-200826.

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Background: Various reasons may lead to cognitive symptoms in elderly, including the development of cognitive decline and dementia. Often, mixed pathologies such as neurodegeneration and cerebrovascular disease co-exist in these patients. Diagnostic work-up commonly includes imaging modalities such as FDG PET, MRI, and CT, each delivering specific information. Objective: To study the informative value of neuroimaging-based data supposed to reflect neurodegeneration (FDG PET), cerebral small vessel disease (MRI), and cerebral large vessel atherosclerosis (CT) with regard to cognitive performanc

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Pietrzyk, U. "Does PET/CT render software registration obsolete?" Nuklearmedizin 44, S 01 (2005): S13—S17. http://dx.doi.org/10.1055/s-0038-1625209.

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Summary:It was the success of software-based image registration that eventually led to the introduction of hardware-based concepts for image fusion, such as combined PET/CT tomographs. A prototype PET/CT was first presented in 1998, with various commercial designs to follow since 2000. PET/ CT is used primarily as a diagnostic modality in the field of extra-cerebral oncology imaging. The major advantage of combined imaging over retrospective software registration is the nearly identical position of the patient during both complementary examination, and therefore tomograms of identical parts of

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van Geel, Jasper J. L., Erik F. J. de Vries, Michel van Kruchten, Geke A. P. Hospers, Andor W. J. M. Glaudemans, and Carolina P. Schröder. "Molecular imaging as biomarker for treatment response and outcome in breast cancer." Therapeutic Advances in Medical Oncology 15 (January 2023): 175883592311707. http://dx.doi.org/10.1177/17588359231170738.

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Molecular imaging, such as positron emission tomography (PET), is increasingly used as biomarker to predict and assess treatment response in breast cancer. The number of biomarkers is expanding with specific tracers for tumour characteristics throughout the body and this information can be used to aid the decision-making process. These measurements include metabolic activity using [18F]fluorodeoxyglucose PET ([18F]FDG-PET), oestrogen receptor (ER) expression using 16α-[18F]Fluoro-17β-oestradiol ([18F]FES)-PET and human epidermal growth factor receptor 2 (HER2) expression using PET with radiola

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Perez-Liva, Mailyn, Thulaciga Yoganathan, Joaquin L. Herraiz, et al. "Ultrafast Ultrasound Imaging for Super-Resolution Preclinical Cardiac PET." Molecular Imaging and Biology 22, no. 5 (2020): 1342–52. http://dx.doi.org/10.1007/s11307-020-01512-w.

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Abstract Purpose Physiological motion and partial volume effect (PVE) significantly degrade the quality of cardiac positron emission tomography (PET) images in the fast-beating hearts of rodents. Several Super-resolution (SR) techniques using a priori anatomical information have been proposed to correct motion and PVE in PET images. Ultrasound is ideally suited to capture real-time high-resolution cine images of rodent hearts. Here, we evaluated an ultrasound-based SR method using simultaneously acquired and co-registered PET-CT-Ultrafast Ultrasound Imaging (UUI) of the beating heart in closed

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