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1

Gulec, Seza A. "PET probe-guided surgery." Journal of Surgical Oncology 96, no. 4 (2007): 353–57. http://dx.doi.org/10.1002/jso.20862.

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Rinehardt, Hannah N., Sadie Longo, Ryan Gilbert, et al. "Handheld PET Probe for Pediatric Cancer Surgery." Cancers 14, no. 9 (2022): 2221. http://dx.doi.org/10.3390/cancers14092221.

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18F-fluorodeoxyglucose (FDG) is a glucose analog that acts as a marker for glucose uptake and metabolism. FDG PET scans are used in monitoring pediatric cancers. The handheld PET probe localization of FDG-avid lesions is an emerging modality for radio-guided surgery (RGS). We sought to assess the utility of PET probe in localizing occult FDG-avid tumors in pediatric patients. PET probe functionality was evaluated by using a PET/CT scan calibration phantom. The PET probe was able to detect FDG photon emission from simulated tumors with an expected decay of the radioisotope over time. Specificit
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3

Schaer, Michael. "Surgery in the Diabetic Pet." Veterinary Clinics of North America: Small Animal Practice 25, no. 3 (1995): 651–60. http://dx.doi.org/10.1016/s0195-5616(95)50060-9.

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4

Di Micco, Rosa, Letizia Santurro, Maria Luisa Gasparri, et al. "PET/MRI for Staging the Axilla in Breast Cancer: Current Evidence and the Rationale for SNB vs. PET/MRI Trials." Cancers 13, no. 14 (2021): 3571. http://dx.doi.org/10.3390/cancers13143571.

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Axillary surgery in breast cancer (BC) is no longer a therapeutic procedure but has become a purely staging procedure. The progressive improvement in imaging techniques has paved the way to the hypothesis that prognostic information on nodal status deriving from surgery could be obtained with an accurate diagnostic exam. Positron emission tomography/magnetic resonance imaging (PET/MRI) is a relatively new imaging tool and its role in breast cancer patients is still under investigation. We reviewed the available literature on PET/MRI in BC patients. This overview showed that PET/MRI yields a hi
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Abou Karam, Gaby, and Ajay Malhotra. "PET/CT May Assist in Avoiding Pointless Thyroidectomy in Indeterminate Thyroid Nodules: A Narrative Review." Cancers 15, no. 5 (2023): 1547. http://dx.doi.org/10.3390/cancers15051547.

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Indeterminate thyroid nodules (ITN) are commonly encountered among the general population, with a malignancy rate of 10 to 40%. However, many patients may be overtreated with futile surgery for benign ITN. To avoid unnecessary surgery, PET/CT scan is a possible alternative to help differentiate between benign and malignant ITN. In this narrative review, the major results and limitations of the most recent studies on PET/CT efficacy (from PET/CT visual assessment to quantitative PET parameters and recent radiomic features analysis) and on cost-effectiveness (compared to other alternatives (such
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6

Ghanta, Bhargavi, Thavam C. Thambi-Pillai, Gary Timmerman, Christopher Fischer, Annie Nelson, and Jonathan Scott Bleeker. "Role of FDG PET/CT scan in preoperative pancreatic cancer staging." Journal of Clinical Oncology 36, no. 4_suppl (2018): 511. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.511.

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511 Background: Guidelines do not recommend routine FDG PET/CT (PET) as preoperative staging for pancreatic cancer, although many single center series have demonstrated that PET can lead to changes in management in a sizable minority of patients. We performed a retrospective analysis of patients undergoing PET for potentially resectable pancreatic adenocarcinoma at our institution to help define the utility of PET in this setting. Methods: We reviewed patients with pancreatic adenocarcinoma diagnosed at our center from June 2010 to May 2017 and included patients with pancreatic adenocarcinoma
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7

Delbeke, Dominique, and William H. Martin. "PET and PET/CT for Pancreatic Malignancies." Surgical Oncology Clinics of North America 19, no. 2 (2010): 235–54. http://dx.doi.org/10.1016/j.soc.2009.11.005.

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8

Zhang, Ru-fan, Yue-dong Shi, Yong Zhang, Yan-wen Yang, and Fa-Zhi Qi. "PET/CT Recognition of Costal Cartilage Infection After Breast Implant Surgery." Annals of Plastic Surgery 93, no. 2S (2024): S47—S50. http://dx.doi.org/10.1097/sap.0000000000004002.

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Background Postoperative infection of breast implants can lead to implant removal and other complications. This study aimed to investigate the presence of costal cartilage infection following breast implant surgery and the diagnostic role of PET/CT in identifying this rare complication. Patients and Methods A retrospective study included 16 patients with persistent infections after breast implant removal surgery. Patients underwent PET/CT scans before surgery, and surgical plans were made based on PET/CT findings. Surgical procedures were guided by PET/CT, and specimens were collected for path
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9

Rathore, Chaturbhuj, John C. Dickson, Rute Teotónio, Peter Ell, and John S. Duncan. "The utility of 18F-fluorodeoxyglucose PET (FDG PET) in epilepsy surgery." Epilepsy Research 108, no. 8 (2014): 1306–14. http://dx.doi.org/10.1016/j.eplepsyres.2014.06.012.

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10

Carr, John. "Reproductive surgery in the pet pig." In Practice 23, no. 2 (2001): 98–101. http://dx.doi.org/10.1136/inpract.23.2.98.

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11

Wang, Yubo, Douglas Steinke, Sean P. Gavan, et al. "Survival Outcomes in Older Women with Oestrogen-Receptor-Positive Early-Stage Breast Cancer: Primary Endocrine Therapy vs. Surgery by Comorbidity and Frailty Levels." Cancers 16, no. 4 (2024): 749. http://dx.doi.org/10.3390/cancers16040749.

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Primary endocrine therapy (PET) offers non-surgical treatment for older women with early-stage breast cancer who are unsuitable for surgery due to frailty or comorbidity. This research assessed all-cause and breast cancer-specific mortality of PET vs. surgery in older women (≥70 years) with oestrogen-receptor-positive early-stage breast cancer by frailty and comorbidity levels. This study used UK secondary data to analyse older female patients from 2000 to 2016. Patients were censored until 31 May 2019 and grouped by the Charlson comorbidity index (CCI) and hospital frailty risk score (HFRS).
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12

Rep, Sebastijan, Klara Sirca, Ema Macek Lezaic, Katja Zaletel, Marko Hocevar, and Luka Lezaic. "[18F]fluorocholine PET vs. [99mTc]sestamibi scintigraphy for detection and localization of hyperfunctioning parathyroid glands in patients with primary hyperparathyroidism: outcomes and resource efficiency." Radiology and Oncology 58, no. 4 (2024): 486–93. http://dx.doi.org/10.2478/raon-2024-0058.

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Abstract Background Minimally invasive parathyroidectomy is the treatment of choice in patients with primary hyperparathyroidism (PHP), but it needs a reliable preoperative localization method to detect hyperfunctioning parathyroid tissue. Higher sensitivity and lower radiation exposure was demonstrated for [18F]fluorocholine PET/CT (FCh-PET/CT) in comparison to [99mTc]sestamibi (MIBI) scintigraphy. However, data of its efficiency in resource use and patient outcomes is lacking. The aim of our study was to determine the resource efficiency and patient outcomes of FCh-PET/CT in comparison to co
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13

Holzgreve, Adrien, Nathalie L. Albert, Norbert Galldiks, and Bogdana Suchorska. "Use of PET Imaging in Neuro-Oncological Surgery." Cancers 13, no. 9 (2021): 2093. http://dx.doi.org/10.3390/cancers13092093.

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This review provides an overview of current applications and perspectives of PET imaging in neuro-oncological surgery. The past and future of PET imaging in the management of patients with glioma and brain metastases are elucidated with an emphasis on amino acid tracers, such as O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET). The thematic scope includes surgical resection planning, prognostication, non-invasive prediction of molecular tumor characteristics, depiction of intratumoral heterogeneity, response assessment, differentiation between tumor progression and treatment-related changes, and em
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14

Serrano Aybar, Pablo Emilio, Julian Felipe Daza, Natalie Solis, Sameer Parpia, Steven Gallinger, and Carolanne Moulton. "Systematic review and meta-analysis of the effect of pre-operative PET/PET-CT in the management of patients with potentially resectable colorectal cancer liver metastasis." Journal of Clinical Oncology 36, no. 4_suppl (2018): 591. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.591.

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591 Background: It has been proposed that PET with 18F-fluorodeoxyglucose alone or combined with CT improves detection of extra hepatic disease in the setting of colorectal cancer liver metastasis (CRLM). However, there remains conflicting evidence on the added benefit of PET/PET-CT prior to liver resection, and its effect on long-term survival. Thus, we set out to perform a systematic review of literature and meta-analysis. Methods: From 2000 to April 2017, MEDLINE, EMBASE, and CENTRAL were searched for studies (prospective and retrospective) investigating the preoperative use of PET/PET-CT i
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15

Wylie, S., and D. Ravichandran. "A UK national survey of breast surgeons on primary endocrine therapy of early operable breast cancer." Annals of The Royal College of Surgeons of England 95, no. 5 (2013): 353–56. http://dx.doi.org/10.1308/003588413x13629960045832.

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Introduction A significant proportion of elderly breast cancer patients in the UK have no surgical treatment recorded and appear to be treated with primary endocrine therapy (PET) only. Despite this, PET remains one of the poorly studied areas in breast cancer therapy and very little is known about the practice of PET in the UK. Methods A questionnaire comprising 14 questions relevant to PET was sent to 489 breast surgeons who were members of the UK Association of Breast Surgery and returned questionnaires were analysed. Results Overall, 228 questionnaires (47%) were returned. The vast majorit
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16

Aslanidi, I. P., E. Z. Golukhova, D. M. Pursanova, et al. "Analysis of factors affecting the accuracy of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in case of suspected prosthetic valve infective endocarditis." Russian Journal of Cardiology 26, no. 12 (2021): 4764. http://dx.doi.org/10.15829/1560-4071-2021-4764.

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Aim. To analyze the factors affecting the accuracy of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography (PET/CT) in case of suspected prosthetic valve endocarditis (PVE).Material and methods. The results of PET/CT performed in 66 patients after heart valve replacement were analyzed: 55 patients with suspected PVE (≥3 months after surgery) and 11 comparison groups without PVE (2 months after surgery). In the group with suspected PVE (n=55) at the time of the study, 27% (15/55) had a normal body temperature, 85% (47/55) — no leukocytosis. In 16% (9/55), the ex
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17

Su, Chih-Hsiung, Wan-Ming Chen, Ming-Chih Chen, Ben-Chang Shia, and Szu-Yuan Wu. "The Association of Preoperative PET-CT and Survival in Patients with Resectable Cervical Cancer." Journal of Clinical Medicine 11, no. 23 (2022): 7143. http://dx.doi.org/10.3390/jcm11237143.

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Purpose: No randomized study with a long-term follow-up has investigated the effect of pretreatment 18-fluorodeoxyglucose positron emission tomography–computed tomography (18FDG-PET–CT) on the survival of patients with stage IB-IIA cervical cancer receiving curative surgery. Therefore, in this propensity score–matched, population-based cohort study, we investigated the effect of preoperative 18FDG-PET–CT on the survival outcomes of patients with potentially resectable cervical cancer. Patients and Methods: We included 2550 patients with stage IB-IIA cervical cancer receiving curative surgery w
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Adua, Daniela, Francesca Sperandi, Paolo Castellucci, et al. "Prognostic factors in malignant pleural mesothelioma (MPM): A mono-institutional evaluation of Bologna Malignant Pleural Mesothelioma Group." Journal of Clinical Oncology 31, no. 15_suppl (2013): e18509-e18509. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e18509.

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e18509 Background: The prognostic systems currently in use in MPM, such as the EORTC and CALGB score, include the clinical and histological parameters, excluding the FDG-PET (PET) evaluation and the possibility of surgery. The aim of our study was to investigate the role of PET baseline SUV-max and surgery as prognostic factors in MPM. Methods: From April 2002to December 2012, 48 pts with a certain histological diagnosis of MPM underwent staging by PET scan before peri-operative (multimodality treatment) or palliative first-line chemotherapy (CT). Surgery was performed in 22(45.8%) pts. Pt cha
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19

Kim, Soyoun Rachel, Yoo-Young Lee, Harinder Brar, et al. "Utility of 18F-FDG-PET/CT imaging in patients with recurrent gynecological malignancies prior to pelvic exenteration." International Journal of Gynecologic Cancer 29, no. 4 (2019): 816–20. http://dx.doi.org/10.1136/ijgc-2018-000091.

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BackgroundIn patients with recurrent gynecologic malignancies isolated to the pelvis, pelvic exenteration is a potential option. 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), is often used to confirm no evidence of metastatic disease.ObjectiveTo assess the impact of PET/CT on clinical management of patients with recurrent gynecologic malignancies being considered for pelvic exenteration.MethodsPatients with recurrent gynecological malignancies who underwent PET/CT imaging between 2011 and 2014 were identified. All were considered for pelvic exenter
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Pak, Kyoungjune, Seong-Jang Kim, In Joo Kim, Bo Hyun Kim, Sang Soo Kim, and Yun Kyung Jeon. "The role of 18F-fluorodeoxyglucose positron emission tomography in differentiated thyroid cancer before surgery." Endocrine-Related Cancer 20, no. 4 (2013): R203—R213. http://dx.doi.org/10.1530/erc-13-0088.

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The incidence of thyroid cancer in both men and women is increasing faster than that of any other cancer. Although positron emission tomography (PET) using18F-fluorodeoxyglucose (FDG) has received much attention, the use of FDG PET for the management of thyroid cancer is limited primarily to postoperative follow-up. However, it might have a role in selected, more aggressive pathologies, and so patients at a high risk of distant metastasis may benefit from PET before surgery. As less FDG-avid thyroid cancers may lower the diagnostic accuracy of PET in preoperative assessment, an understanding o
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21

Wu Shun Felix Wong and Kwok To Thomas Li. "False-positive diagnosis of uterine malignancy with raised 18F-fluorodeoxyglucose activity in adenomyosis: A case report." World Journal of Advanced Research and Reviews 13, no. 2 (2022): 367–70. http://dx.doi.org/10.30574/wjarr.2022.13.2.0178.

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Positron Emission Tomography - Computed Tomography (PET-CT) has been used to diagnose malignancy before surgery. However, there may be an increase in 18F-fluorodeoxyglucose (FDG) uptake in PET scans in benign conditions, leading to a false-positive diagnosis of malignancy and unnecessary surgery. This PET-CT investigation is expensive and is not without risk, including radiation and drug or contrast hypersensitivity. Although variable uterine uptakes of FDG activities in PET-CT had been reported in the literature, unawareness of its possibility in benign conditions could lead to a false alarm
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Wu, Shun Felix Wong, and To Thomas Li Kwok. "False-positive diagnosis of uterine malignancy with raised 18F-fluorodeoxyglucose activity in adenomyosis: A case report." World Journal of Advanced Research and Reviews 13, no. 2 (2022): 367–70. https://doi.org/10.5281/zenodo.6349820.

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Positron Emission Tomography - Computed Tomography (PET-CT) has been used to diagnose malignancy before surgery. However, there may be an increase in 18F-fluorodeoxyglucose (FDG) uptake in PET scans in benign conditions, leading to a false-positive diagnosis of malignancy and unnecessary surgery. This PET-CT investigation is expensive and is not without risk, including radiation and drug or contrast hypersensitivity. Although variable uterine uptakes of FDG activities in PET-CT had been reported in the literature, unawareness of its possibility in benign conditions could lead to a false alarm
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Jang, Su Jin, Jeong Won Lee, Ji-Hyun Lee, In Young Jo, and Sang Mi Lee. "Different Prognostic Values of Dual-Time-Point FDG PET/CT Imaging Features According to Treatment Modality in Patients with Non-Small Cell Lung Cancer." Tomography 8, no. 2 (2022): 1066–78. http://dx.doi.org/10.3390/tomography8020087.

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This study was aimed to investigate whether dual-time-point F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) imaging features had different prognostic values according to the treatment modality in patients with non-small cell lung cancer (NSCLC). We retrospectively reviewed 121 NSCLC patients with surgical resection (surgery group) and 69 NSCLC patients with chemotherapy and/or radiotherapy (CRT group), who underwent pretreatment dual-time-point FDG PET/CT. The maximum standardized uptake value (SUV), metabolic tumor volume (MTV), total lesion glycolysi
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Avril, Norbert, Stephen J. Mather, and Rebecca Roylance. "FDG-PET and PET/CT in Breast Cancer Staging." Breast Care 2, no. 6 (2007): 372–77. http://dx.doi.org/10.1159/000112224.

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Bailey, Christina Edwards, Chung-Yuan Hu, Y. Nancy You, et al. "Population-based trends in positron emission tomography (PET) utilization after resection for colon cancer." Journal of Clinical Oncology 31, no. 4_suppl (2013): 365. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.365.

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365 Background: While most colon cancer staging and treatment guidelines do not routinely include PET imaging, its use has been increasing. The primary aim of this study is to evaluate the trends in PET utilization during the first 2 years after diagnosis of colon cancer. Methods: A retrospective cohort study of patients ≥ 65 years old with colon cancer who underwent surgical resection in the Surveillance, Epidemiology, and End Results-linked Medicare database (2001-2007, Medicare Part A/B only) and had at least 2 years of follow-up was performed. PET utilization was assessed using the test fo
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Chan, Shaun WY, Patrick MY Chan, Melanie DW Seah, Juliana JC Chen, and Ern Yu Tan. "Limiting the Use of Primary Endocrine Therapy in Elderly Women With Breast Cancer." Annals of the Academy of Medicine, Singapore 43, no. 9 (2014): 469–72. http://dx.doi.org/10.47102/annals-acadmedsg.v43n9p469.

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Primary endocrine therapy (PET) is often included as a treatment option in elderly women with operable breast cancer. Elderly women tend to have pre-existing comorbidities and are often reluctant to undergo surgery. The benefit of surgery needs to be weighed against a relatively higher potential for operative morbidity and mortality, and a limited life expectancy. But while PET can provide relatively good locoregional control, it is not curative in nature and the possibility of local complications and metastasis remains. We retrospectively reviewed the outcome of PET in a series of 19 elderly
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Muraglia, Lorenzo, Francesco Mattana, Laura Lavinia Travaini, et al. "First Live-Experience Session with PET/CT Specimen Imager: A Pilot Analysis in Prostate Cancer and Neuroendocrine Tumor." Biomedicines 11, no. 2 (2023): 645. http://dx.doi.org/10.3390/biomedicines11020645.

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Objective: to evaluate the feasibility of the intra-operative application of a specimen PET/CT imager in a clinical setting. Materials and methods: this is a pilot analysis performed in three patients who received an intra-operative administration of 68Ga-PSMA-11 (n = 2) and 68Ga-DOTA-TOC (n = 1), respectively. Patients were administrated with PET radiopharmaceuticals to perform radio-guided surgery with a beta-probe detector during radical prostatectomy for prostate cancer (PCa) and salvage lymphadenectomy for recurrent neuroendocrine tumor (NET) of the ileum, respectively. All procedures hav
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Mattoli, Maria Vittoria, Giorgio Treglia, Maria Lucia Calcagni, Annunziato Mangiola, Carmelo Anile, and Gianluca Trevisi. "Usefulness of Brain Positron Emission Tomography with Different Tracers in the Evaluation of Patients with Idiopathic Normal Pressure Hydrocephalous." International Journal of Molecular Sciences 21, no. 18 (2020): 6523. http://dx.doi.org/10.3390/ijms21186523.

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Idiopathic normal pressure hydrocephalus (iNPH) is the only form of dementia that can be cured by surgery. Its diagnosis relies on clinical and radiological criteria. Identifying patients who can benefit from surgery is challenging, as other neurological diseases can be concomitant or mimic iNPH. We performed a systematic review on the role of positron emission tomography (PET) in iNPH. We retrieved 35 papers evaluating four main functional aspects with different PET radiotracers: (1) PET with amyloid tracers, revealing Alzheimer’s disease (AD) pathology in 20–57% of suspected iNPH patients, c
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29

de Koster, Elizabeth J., Lioe-Fee de Geus-Oei, Adrienne H. Brouwers, et al. "[18F]FDG-PET/CT to prevent futile surgery in indeterminate thyroid nodules: a blinded, randomised controlled multicentre trial." European Journal of Nuclear Medicine and Molecular Imaging 49, no. 6 (2022): 1970–84. http://dx.doi.org/10.1007/s00259-021-05627-2.

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Abstract Purpose To assess the impact of an [18F]FDG-PET/CT-driven diagnostic workup to rule out malignancy, avoid futile diagnostic surgeries, and improve patient outcomes in thyroid nodules with indeterminate cytology. Methods In this double-blinded, randomised controlled multicentre trial, 132 adult euthyroid patients with scheduled diagnostic surgery for a Bethesda III or IV thyroid nodule underwent [18F]FDG-PET/CT and were randomised to an [18F]FDG-PET/CT-driven or diagnostic surgery group. In the [18F]FDG-PET/CT-driven group, management was based on the [18F]FDG-PET/CT result: when the i
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Goodman, Karyn A., Donna Niedzwiecki, Nathan Hall, et al. "Initial results of CALGB 80803 (Alliance): A randomized phase II trial of PET scan-directed combined modality therapy for esophageal cancer." Journal of Clinical Oncology 35, no. 4_suppl (2017): 1. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.1.

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1 Background: To determine whether changing chemotherapy (CT) during pre-op chemoradiation (CRT) based on response to induction CT by 18F-fluoro-deoxyglucose PET imaging can lead to improved pathologic complete response (pCR) in patients (pts) with resectable esophageal and gastroesophageal junction (GEJ) adenocarcinomas. Methods: 257 eligible pts were enrolled, underwent baseline PET scan, and were randomized to one of 2 induction CT arms: Modified FOLFOX-6 (oxaliplatin, leucovorin, 5-FU), days 1, 15, 29 or Carboplatin/Paclitaxel (CP), days 1, 8, 22, 29. Repeat PET was performed days 36-42; c
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Yu, Irene S., Shiru Lucy Liu, Yizhou Zhao, Sally CM Lau, and Howard John Lim. "Relationship between PET response and pathologic response in distal esophageal/gastroesophageal junction (DE/GEJ) cancers." Journal of Clinical Oncology 38, no. 4_suppl (2020): 452. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.452.

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452 Background: The utility of PET scans (PETs) to predict outcomes after neoadjuvant treatment of DE/GEJ cancers is unclear. We aimed to explore the relationship between PET response and pathologic/clinical outcomes in a real-world setting. Methods: Patients (pts) with DE/GEJ cancer treated with curative intent perioperative chemotherapy or neoadjuvant chemoradiation followed by surgery in British Columbia from 2009-2018 were included. Retrospective chart review was conducted; pts were stratified into PET responder (R, ≥ 35% decrease in max SUV) and non-responder (NR, < 35%) groups. Chi-sq
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Aslan, Muhyettin, Pınar Bıçakçıoğlu, Koray Aydoğdu, et al. "Comparison of 18F-FDG and 68Ga-DOTATATE PET/CT in surgically treated lung carcinoid tumors." Journal of Pulmonology and Intensive Care 2, no. 4 (2024): 77–80. https://doi.org/10.51271/jopic-0042.

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Aims: This study aims to compare the efficacy of FDG-18 PET/CT and 68Ga-DOTATATE PET/CT imaging techniques in patients with lung carcinoid tumors, identifying the most appropriate preoperative nuclear medicine technique for diagnosis and staging. Methods: We retrospectively analyzed data from 123 patients who underwent surgery for lung carcinoid tumors at our center between 2009 and 2021. All of the patients were scanned with FDG-18 PET/CT before surgery. In addition to FDG-18 PET/CT, 68Ga-DOTATATE PET/CT scanning was performed in 28 patients: 17 in the preoperative and 11 in the postoperative
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Atici, Ali E., Tebessum Cakir, Enver Reyhan, et al. "Preoperative Use of PET/CT in Patients With Colorectal and Gastric Cancer and Its Impact on Treatment Decision Making." International Surgery 101, no. 7-8 (2016): 318–27. http://dx.doi.org/10.9738/intsurg-d-16-00006.1.

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The advantages of primary positron emission tomography–computed tomography (PET-CT) evaluation of both cancers needs to be clarified. This study aimed to investigate the efficacy of PET-CT compared with computed tomography (CT) in preoperative evaluation of colorectal and gastric cancer patients, and to determine its effects on treatment decision-making. We prospectively evaluated patients who presented with both types of cancer in our clinic between September 2008 and June 2010, using PET-CT and CT. We compared the results with histopathologic findings and determined the changing treatment st
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Boykin, K. N., Gazi B. Zibarl, D. L. Lilien, R. W. Mcmillan, D. F. Aultman, and J. C. Mcdonald. "The Use of FDG-Positron Emission Tomography for the Evaluation of Colorectal Metastases of the Liver." American Surgeon 65, no. 12 (1999): 1183–85. http://dx.doi.org/10.1177/000313489906501220.

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Each year at least 130,000 people in the United States are diagnosed with colorectal carcinoma. Approximately 14,000 of these patients will have liver metastases, and 20 per cent of these patients will die from these metastases. Surgical resection is the only possible chance for cure in patients with only intrahepatic metastases, and extrahepatic disease is a contraindication to glucose metabolism. Positron emission tomography (PET) allows the in vivo study of the uptake and use of glucose in human cells. Here, we review our experience with the use of PET imaging for the diagnosis and manageme
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MAISEY, M. N. "Clinical PET in cardiology and cardiac surgery." Nuclear Medicine Communications 21, no. 3 (2000): 234–36. http://dx.doi.org/10.1097/00006231-200003000-00006.

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Eirini, Liodaki, Liodakis Emmanouil, Papadopoulos Othonas, Machens Hans-Günther, and Papadopulos A. Nikolaos. "PET scanning in plastic and reconstructive surgery." Annals of Nuclear Medicine 26, no. 2 (2012): 115–22. http://dx.doi.org/10.1007/s12149-011-0557-0.

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37

Goyal, Bhupesh K., Harkirat Singh, Krishan Kapur, Bhupinder S. Duggal, and Mattakarottu J. Jacob. "Value of PET-CT in Avoiding Multimodality Therapy in Operable Cervical Cancer." International Journal of Gynecologic Cancer 20, no. 6 (2010): 1041–45. http://dx.doi.org/10.1111/igc.0b013e3181dcadeb.

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Background:Posttreatment morbidity of multimodality therapy is substantially higher than either radical surgery or chemoradiation alone. Preoperative prediction of positive nodes limits optimal selection of the primary treatment modality. Computed tomography (CT) and magnetic resonance imaging have been tried for nodal assessment with modest results. Positron emission tomography (PET) combined with CT seems to be promising in this regard. This clinicopathologic study assesses the value of PET-CT in predicting nodal metastasis and avoiding multimodality therapy.Materials and Methods:Eighty pati
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Koroglu, E., S. Sirin, and S. Isgoren. "The Importance of the Time Interval Between Preoperative 18F-FDG PET/CT Imaging and Neck Dissection for the Detection of Nodal Metastases in Patients with Head and Neck Squamous Cell Carcinoma." Nigerian Journal of Clinical Practice 27, no. 7 (2024): 859–64. http://dx.doi.org/10.4103/njcp.njcp_38_24.

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Background: Detection of nodal metastasis is critical for the treatment and prognosis of head and neck cancer (HNC). Positron emission tomography/computed tomography (PET/CT) is increasingly being used to detect cervical lymph node involvement. Aim: The purposes of this study were to (1) investigate the diagnostic accuracy of PET/CT for the detection of neck metastasis in patients with HNC and (2) determine the effect of the time interval between surgery and PET/CT. Methods: Fifty patients with head and neck squamous cell carcinoma who underwent PET/CT before surgery were included in this stud
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Uporov, Anton, Samantha Taber, Lope Estèvez Schwarz, et al. "Implication of FDG-PET/CT in patients with potentially operable colorectal lung metastases." Innovative Surgical Sciences 6, no. 3 (2021): 89–95. http://dx.doi.org/10.1515/iss-2021-0029.

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Abstract Objectives This prospective study assessed the role of F-18-FDG-PET/CT in clinical staging for patients with colorectal cancer planned for pulmonary metastasectomy by thoracotomy or video-assisted surgery. Patients and methods In addition to conventional imaging, we performed 86 F-18-FDG-PET/CT studies in 76 patients with potentially resectable metastatic colorectal lung metastases. We then investigated the effect that PET/CT had on further clinical management. Based on the results from the 47 thoracotomies performed, we compared the number of pulmonary metastases discovered after his
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Gómez León, Nieves, Sofía Escalona, Beatriz Bandrés, Cristobal Belda, Daniel Callejo, and Juan Antonio Blasco. "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Accuracy in the Staging of Non-Small Cell Lung Cancer: Review and Cost-Effectiveness." Radiology Research and Practice 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/135934.

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Aim of the performed clinical study was to compare the accuracy and cost-effectiveness of PET/CT in the staging of non-small cell lung cancer (NSCLC).Material and Methods. Cross-sectional and prospective study including 103 patients with histologically confirmed NSCLC. All patients were examined using PET/CT with intravenous contrast medium. Those with disease stage ≤IIB underwent surgery (n=40). Disease stage was confirmed based on histology results, which were compared with those of PET/CT and positron emission tomography (PET) and computed tomography (CT) separately. 63 patients classified
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González, Segundo J., Joyce Wong, Lorena González, et al. "Novel handheld PET probes provide intraoperative localization of PET-avid lymph nodes." Surgical Endoscopy 25, no. 10 (2011): 3214–21. http://dx.doi.org/10.1007/s00464-011-1696-z.

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García, J. R., M. Fraile, M. Soler, J. Bechini, J. R. Ayuso, and F. Lomeña. "PET/CT-guided salvage surgery protocol. Results with ROLL technique and PET probe." Revista Española de Medicina Nuclear (English Edition) 30, no. 4 (2011): 217–22. http://dx.doi.org/10.1016/j.remngl.2011.02.003.

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Lim, Chae Hong, Soo Bin Park, Hong Kwan Kim, et al. "Clinical Value of Surveillance 18F-fluorodeoxyglucose PET/CT for Detecting Unsuspected Recurrence or Second Primary Cancer in Non-Small Cell Lung Cancer after Curative Therapy." Cancers 14, no. 3 (2022): 632. http://dx.doi.org/10.3390/cancers14030632.

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We evaluated the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT surveillance for detecting clinically unsuspected recurrence or second primary cancer (SPC) in patients with non-small cell lung cancer (NSCLC) after curative therapy. A total of 4478 surveillance FDG PET/CT scans from 2864 NSCLC patients without suspicion of recurrence after curative therapy were reviewed retrospectively. In 274 of 2864 (9.6%) patients, recurrent NSCLC or SPC was found by surveillance PET/CT during clinical follow-up. Surveillance PET/CT scans showed sensitivity of 98.9% (2
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Lim, Chae Hong, Sang-Won Um, Hong Kwan Kim, et al. "18F-Fluorodeoxyglucose Positron Emission Tomography-Based Risk Score Model for Prediction of Five-Year Survival Outcome after Curative Resection of Non-Small-Cell Lung Cancer." Cancers 16, no. 14 (2024): 2525. http://dx.doi.org/10.3390/cancers16142525.

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The aim of our retrospective study is to develop and assess an imaging-based model utilizing 18F-FDG PET parameters for predicting the five-year survival in non-small-cell lung cancer (NSCLC) patients after curative surgery. A total of 361 NSCLC patients who underwent curative surgery were assigned to the training set (n = 253) and the test set (n = 108). The LASSO regression model was used to construct a PET-based risk score for predicting five-year survival. A hybrid model that combined the PET-based risk score and clinical variables was developed using multivariate logistic regression analy
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Gordin, Arie, Avishay Golz, Zohar Keidar, Marcello Daitzchman, Rachel Bar-Shalom, and Ora Israel. "The Role of FDG-PET/CT Imaging in Head and Neck Malignant Conditions: Impact on Diagnostic Accuracy and Patient Care." Otolaryngology–Head and Neck Surgery 137, no. 1 (2007): 130–37. http://dx.doi.org/10.1016/j.otohns.2007.02.001.

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BACKGROUND: To assess the value of positron emission tomography/computed tomography (PET/CT) with 18 F-Fluorodeoxyglucose (FDG) in patients with head and neck carcinoma as compared with PET and conventional imaging alone, and to assess the impact of PET/CT on further clinical management. STUDY DESIGN: Prospective nonrandomized study. SETTING: Ninety patients with head and neck tumors had 107 PET/CT examinations. RESULTS: The study analysis showed that PET/CT had a sensitivity of 89%, specificity 95%, PPV 94%, NPV 90%, and accuracy of 92%. PET/CT altered management in 51 patients (56%). PET/CT
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Traub-Weidinger, Tatjana, Philip Weidinger, Gundrun Gröppel, et al. "Presurgical evaluation of pediatric epilepsy patients prior to hemispherotomy: the prognostic value of 18F-FDG PET." Journal of Neurosurgery: Pediatrics 18, no. 6 (2016): 683–88. http://dx.doi.org/10.3171/2016.5.peds1652.

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OBJECTIVE The objective of this study was to investigate whether fluorine-18 fluorodeoxyglucose PET (18F-FDG PET) can help to predict seizure outcome after hemispherotomy and therefore may be useful in decision making and patient selection. METHODS Children and adolescents less than 18 years of age who underwent 18F-FDG PET studies during presurgical evaluation prior to hemispherotomy and had follow-up data of at least 12 months after surgery were included. Seizure outcome was classified according to the recommendations of the International League Against Epilepsy. PET data were reevaluated by
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Takahara, Kohei, Hiroaki Kakinoki, Saya Ikoma, et al. "Suture Granuloma Showing False-Positive Findings on FDG-PET." Case Reports in Urology 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/472642.

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We report a case of a 33-year-old male with a mixed germ-cell testicular tumor. Postoperative follow-up FDG-PET revealed concentration of FDG in the left inguinal area which is not tumor metastasis or local recurrence but suture reactivity granuloma. In this paper, we reviewed suture granulomas associated with false-positive findings on FDG-PET after surgery. If FDG-PET will be used more frequently in the future, it will be necessary to refrain from using silk thread in order to prevent any unnecessary surgery.
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Yu, Irene S., Shiru Lucy Liu, Yizhou Zhao, et al. "Relationship between PET response and pathologic response in distal esophageal/gastroesophageal junction cancers: A provincial population-based analysis." Journal of Clinical Oncology 37, no. 15_suppl (2019): e15506-e15506. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e15506.

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e15506 Background: The utility of PET scans (PETs) to predict outcomes after neoadjuvant treatment of DE/GEJ cancers is unclear. We aimed to explore the relationship between PET response and pathologic/clinical outcomes in a real-world setting. Methods: Patients (pts) with DE/GEJ cancer treated with curative intent perioperative chemotherapy or neoadjuvant chemoradiation followed by surgery in British Columbia from 2009-2018 were included. Retrospective chart review was conducted; pts were stratified into PET responders (R, ≥ 35% decrease in max SUV) or PET non-responders (NR, < 35%) groups
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Okamoto, Kentaro, Yukiko Tani, Takeshi Yamaguchi, et al. "Asymptomatic Mesenchymal Hamartoma of the Chest Wall in Child With Fluorodeoxyglucose Uptake on PET/CT—Report of a Case." International Surgery 100, no. 5 (2015): 915–19. http://dx.doi.org/10.9738/intsurg-d-14-00083.1.

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We had experience with a case of mesenchymal hamartoma of the chest wall (MHCW) with fluorodeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT). We reported the first case of asymptomatic MHCW in a child with preoperative PET/CT. Mesenchymal hamartoma of the chest wall is a rare benign tumor that usually presents as a visible chest wall mass or respiratory problems secondary to compression of the lung in early infancy. It is often reported that malignant transformation is extraordinarily rare. Positron emission tomography/CT is useful for diagnosis of malignan
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Pirotte, Benoit J. M., Alphonse Lubansu, Nicolas Massager, et al. "Clinical impact of integrating positron emission tomography during surgery in 85 children with brain tumors." Journal of Neurosurgery: Pediatrics 5, no. 5 (2010): 486–99. http://dx.doi.org/10.3171/2010.1.peds09481.

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Object In this paper, the authors' goal was to evaluate the impact of PET information on brain tumor surgery in children. Methods Between 1995 and 2007, 442 children were referred to the authors' institution for a newly diagnosed brain lesion. Of these, 85 were studied with FDG-PET and/or L-(methyl-11C)-methionine –PET in cases in which MR images were unable to assist in selecting accurate biopsy targets (35 patients) or to delineate tumors for maximal resection (50 patients). In surgical cases, PET and MR images were combined in image fusion planning for stereotactic biopsies or navigation-ba
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