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Journal articles on the topic 'PEVK domain'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Altorjay, Áron Gellért, Hedvig Tordai, Ádám Zolcsák, Nikoletta Kósa, Tamás Hegedűs, and Miklós Kellermayer. "Titin’s Intrinsically Disordered PEVK Domain Modulates Actin Polymerization." International Journal of Molecular Sciences 26, no. 14 (2025): 7004. https://doi.org/10.3390/ijms26147004.

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The multi-domain muscle protein titin provides elasticity and mechanosensing functions to the sarcomere. Titin’s PEVK domain is intrinsically disordered due to the presence of a large number of prolines and highly charged residues. Although PEVK does not have canonical actin-binding motifs, it has been shown to bind F-actin. Here, we explored whether the PEVK domain may also affect actin assembly. We cloned the middle, 733-residue-long segment (called PEVKII) of the full-length PEVK domain, expressed in E. coli and purified by using His- and Avi-tags engineered to the N- and C-termini, respect

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2

Altorjay, Áron, Hedvig Tordai, Ádám Zolcsák, Nikoletta Kosa, and Miklós Kellermayer. "BPS2025 - Titin's PEVK domain modulates actin polymerization." Biophysical Journal 124, no. 3 (2025): 135a. https://doi.org/10.1016/j.bpj.2024.11.755.

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3

Mártonfalvi, Zsolt, Pasquale Bianco, Marco Linari, et al. "Low-force transitions in single titin molecules reflect a memory of contractile history." J Cell Sci. 127 (December 19, 2013): 858–70. https://doi.org/10.1242/jcs.138461.

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Titin is a giant elastomeric muscle protein that has been suggested to function as a sensor of sarcomeric stress and strain, but the mechanisms by which it does so are unresolved. To gain insight into its mechanosensory function we manipulated single titin molecules with high-resolution optical tweezers. Discrete, step-wise transitions, with rates faster than canonical Ig domain unfolding occurred during stretch at forces as low as 5 pN. Multiple mechanisms and molecular regions (PEVK, proximal tandem-Ig, N2A) are likely to be involved. The pattern of transitions is sensitive to the history of

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4

Ayme-Southgate, A., R. A. Philipp, and R. J. Southgate. "Projectin PEVK domain, splicing variants and domain structure in basal and derived insects." Insect Molecular Biology 20, no. 3 (2011): 347–56. http://dx.doi.org/10.1111/j.1365-2583.2011.01069.x.

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5

Nagy, A., L. Grama, T. Huber, et al. "Hierarchical Extensibility in the PEVK Domain of Skeletal-Muscle Titin." Biophysical Journal 89, no. 1 (2005): 329–36. http://dx.doi.org/10.1529/biophysj.104.057737.

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6

Anderson, Brian, Julius Bogolomovas, Siegfried Labeit, and Henk Granzier. "Single Molecule Analysis of PKC Phosphorylation of Titin's PEVK Domain." Biophysical Journal 98, no. 3 (2010): 553a. http://dx.doi.org/10.1016/j.bpj.2009.12.2993.

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7

Nagy, A. "Differential actin binding along the PEVK domain of skeletal muscle titin." Journal of Cell Science 117, no. 24 (2004): 5781–89. http://dx.doi.org/10.1242/jcs.01501.

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8

MIHOVILOVIC, MIRTA, YUN MAI, CAROL AUSTIN, and ALLEN D. ROSES. "Sera from Myasthenia Gravis Patients Recognize the PEVK Domain of Titin." Annals of the New York Academy of Sciences 841, no. 1 MYASTHENIA GR (1998): 534–37. http://dx.doi.org/10.1111/j.1749-6632.1998.tb10977.x.

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9

Linke, Wolfgang A., Michael Kulke, Hongbin Li, et al. "PEVK Domain of Titin: An Entropic Spring with Actin-Binding Properties." Journal of Structural Biology 137, no. 1-2 (2002): 194–205. http://dx.doi.org/10.1006/jsbi.2002.4468.

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10

Linke, Wolfgang A., Diane E. Rudy, Thomas Centner, et al. "I-Band Titin in Cardiac Muscle Is a Three-Element Molecular Spring and Is Critical for Maintaining Thin Filament Structure." Journal of Cell Biology 146, no. 3 (1999): 631–44. http://dx.doi.org/10.1083/jcb.146.3.631.

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In cardiac muscle, the giant protein titin exists in different length isoforms expressed in the molecule's I-band region. Both isoforms, termed N2-A and N2-B, comprise stretches of Ig-like modules separated by the PEVK domain. Central I-band titin also contains isoform-specific Ig-motifs and nonmodular sequences, notably a longer insertion in N2-B. We investigated the elastic behavior of the I-band isoforms by using single-myofibril mechanics, immunofluorescence microscopy, and immunoelectron microscopy of rabbit cardiac sarcomeres stained with sequence-assigned antibodies. Moreover, we overex

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11

Bianco, Pasquale, Attila Nagy, András Kengyel, et al. "Interaction Forces between F-Actin and Titin PEVK Domain Measured with Optical Tweezers." Biophysical Journal 93, no. 6 (2007): 2102–9. http://dx.doi.org/10.1529/biophysj.107.106153.

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12

Ayme-Southgate, Agnes J., Richard J. Southgate, Richard A. Philipp, Erik E. Sotka, and Catherine Kramp. "The Myofibrillar Protein, Projectin, is Highly Conserved Across Insect Evolution Except for Its PEVK Domain." Journal of Molecular Evolution 67, no. 6 (2008): 653–69. http://dx.doi.org/10.1007/s00239-008-9177-2.

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13

Kötter, Sebastian, Andreas Unger, Nazha Hamdani, et al. "Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins." Journal of Cell Biology 204, no. 2 (2014): 187–202. http://dx.doi.org/10.1083/jcb.201306077.

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In myocytes, small heat shock proteins (sHSPs) are preferentially translocated under stress to the sarcomeres. The functional implications of this translocation are poorly understood. We show here that HSP27 and αB-crystallin associated with immunoglobulin-like (Ig) domain-containing regions, but not the disordered PEVK domain (titin region rich in proline, glutamate, valine, and lysine), of the titin springs. In sarcomeres, sHSP binding to titin was actin filament independent and promoted by factors that increased titin Ig unfolding, including sarcomere stretch and the expression of stiff tit

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14

Kellermayer, Dalma, Bálint Kiss, Hedvig Tordai, et al. "Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete’s Heart." International Journal of Molecular Sciences 22, no. 20 (2021): 11110. http://dx.doi.org/10.3390/ijms222011110.

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Long-term exercise induces physiological cardiac adaptation, a condition referred to as athlete’s heart. Exercise tolerance is known to be associated with decreased cardiac passive stiffness. Passive stiffness of the heart muscle is determined by the giant elastic protein titin. The adult cardiac muscle contains two titin isoforms: the more compliant N2BA and the stiffer N2B. Titin-based passive stiffness may be controlled by altering the expression of the different isoforms or via post-translational modifications such as phosphorylation. Currently, there is very limited knowledge about titin’

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15

MIHOVILOVIC, MIRTA, EMMA CIAFALONI, JENNIFER BUTTERWORTH-ROBINETTE, JIAN-PING JIN, JANICE MASSEY, and DONALD B. SANDERS. "Antibodies in Sera of Patients with Late-Onset Myasthenia Gravis Recognize the PEVK Domain of Titin." Annals of the New York Academy of Sciences 998, no. 1 (2003): 351–55. http://dx.doi.org/10.1196/annals.1254.040.

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16

Campbell, Kenneth S., and Martin Lakie. "Response to Bianco et al.: Interaction Forces between F-actin and Titin PEVK Domain Measured with Optical Tweezers." Biophysical Journal 94, no. 1 (2008): 327–28. http://dx.doi.org/10.1529/biophysj.107.114322.

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17

Zhang, Y., D. Featherstone, W. Davis, E. Rushton, and K. Broadie. "Drosophila D-titin is required for myoblast fusion and skeletal muscle striation." Journal of Cell Science 113, no. 17 (2000): 3103–15. http://dx.doi.org/10.1242/jcs.113.17.3103.

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An ethylmethane sulfonate (EMS) mutagenesis of Drosophila melanogaster aimed at discovering novel genes essential for neuromuscular development identified six embryonic lethal alleles of one genetic locus on the third chromosome at 62C. Two additional lethal P element insertion lines, l(3)S02001 and l(3)j1D7, failed to complement each other and each of the six EMS alleles. Analysis of genomic sequence bracketing the two insertion sites predicted a protein of 16,215 amino acid residues, encoded by a 70 kb genomic region. This sequence includes the recently characterized kettin, and includes all

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18

Ma, Kan, and Kuan Wang. "Interaction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulin." FEBS Letters 532, no. 3 (2002): 273–78. http://dx.doi.org/10.1016/s0014-5793(02)03655-4.

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19

Ayme-Southgate, Agnes, Judith Saide, Richard Southgate, et al. "In indirect flight muscles Drosophila projectin has a short PEVK domain, and its NH2-terminus is embedded at the Z-band." Journal of Muscle Research and Cell Motility 26, no. 6-8 (2006): 467–77. http://dx.doi.org/10.1007/s10974-005-9031-8.

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20

Kovács, Árpád, Gábor Á. Fülöp, Andrea Kovács, et al. "Renin overexpression leads to increased titin-based stiffness contributing to diastolic dysfunction in hypertensive mRen2 rats." American Journal of Physiology-Heart and Circulatory Physiology 310, no. 11 (2016): H1671—H1682. http://dx.doi.org/10.1152/ajpheart.00842.2015.

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Hypertension (HTN) is a major risk factor for heart failure. We investigated the influence of HTN on cardiac contraction and relaxation in transgenic renin overexpressing rats (carrying mouse Ren-2 renin gene, mRen2, n = 6). Blood pressure (BP) was measured. Cardiac contractility was characterized by echocardiography, cellular force measurements, and biochemical assays were applied to reveal molecular mechanisms. Sprague-Dawley (SD) rats ( n = 6) were used as controls. Transgenic rats had higher circulating renin activity and lower cardiac angiotensin-converting enzyme two levels. Systolic BP

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21

Kato, M., N. Nagasaki-Takeuchi, Y. Ide, and M. Maeshima. "An Arabidopsis Hydrophilic Ca2+-Binding Protein with a PEVK-Rich Domain, PCaP2, is Associated with the Plasma Membrane and Interacts with Calmodulin and Phosphatidylinositol Phosphates." Plant and Cell Physiology 51, no. 3 (2010): 366–79. http://dx.doi.org/10.1093/pcp/pcq003.

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22

Shur, V. Ya, M. S. Kosobokov, A. V. Makaev, and D. K. Kuznetsov. "Light-induced ordering of nanodomains in lithium tantalate as a result of multiple scanning by IR laser irradiation." Journal of Applied Physics 133, no. 1 (2023): 014105. http://dx.doi.org/10.1063/5.0128980.

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The ordering of a light-induced structure of isolated circular ferroelectric nanodomains was discovered in lithium tantalate crystals under multiple scanning by infrared laser irradiation. The effect was considered as domain arising and growth under the action of alternating in sign pyroelectric field arising during sample heating and subsequent cooling. The circular domains appeared due to 1D to 2D shape transformation after the second scan and grew during subsequent scanning by merging with arising domains accompanied by shape restoration. The ordering of the domain pattern during multiple s

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23

Cairns, S., C. Relf, K. MacLachlan, and W. J. Davis. "Neoarchean decoupling of upper- and mid-crustal tectonothermal domains in the southeast Slave Province: evidence from the Walmsley Lake area." Canadian Journal of Earth Sciences 42, no. 6 (2005): 869–94. http://dx.doi.org/10.1139/e05-057.

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The Walmsley Lake area of the southeastern Slave Province, Northwest Territories, exposes a crustal transect from greenschist through to upper amphibolite facies. Two tectonothermal crustal domains are proposed based on disparate tectonic histories and rock types. Within the upper tectonothermal domain, D1 deformation reached lower amphibolite facies prior to 2614 Ma and associated M1 metamorphic conditions outlasted D1. Peak M2 conditions reached middle amphibolite facies prior to 2603 Ma and outlasted D2 deformation. Deformation style and metamorphic sequencing during these two pre-2600 Ma e

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24

Bertram, F., Daniel Forster, J. Christen, N. Oleynik, Armin Dadgar, and A. Krost. "Microscopic Spatial Distribution of Bound Excitons in High-Quality ZnO." Materials Science Forum 483-485 (May 2005): 1065–0. http://dx.doi.org/10.4028/www.scientific.net/msf.483-485.1065.

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The surface morphology of the ZnO layers is dominated by a distinct hexagonal domain structure. While the laterally integrated cathodoluminescence spectrum shows intense and narrow I8 luminescence, a distinct emission line at spectral position of I0/I1 emerges in the local spectra taken at domain boundaries. In contrast, no I0/I1 emission is found inside the domains. Monochromatic images further evidence the selective incorporation of impurities at the grain boundaries of domains. Monochromatic images of the I8 peak wavelength directly visualize the strain relaxation across the domains towards

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25

Hansen, Dominique, Kim Bonné, Toon Alders, et al. "Exercise training intensity determination in cardiovascular rehabilitation: Should the guidelines be reconsidered?" European Journal of Preventive Cardiology 26, no. 18 (2019): 1921–28. http://dx.doi.org/10.1177/2047487319859450.

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Aims In the rehabilitation of cardiovascular disease patients a correct determination of the endurance-type exercise intensity is important to generate health benefits and preserve medical safety. It remains to be assessed whether the guideline-based exercise intensity domains are internally consistent and agree with physiological responses to exercise in cardiovascular disease patients. Methods A total of 272 cardiovascular disease patients without pacemaker executed a maximal cardiopulmonary exercise test on bike (peak respiratory gas exchange ratio >1.09), to assess peak heart rate (HRpe

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26

Hu, Kejia, Hongyi Li, Di Zhao, Yuan Jiang та Baozhu Li. "Geometric Properties of a General Kohn–Nirenberg Domain in ℂn". Mathematics 13, № 7 (2025): 1200. https://doi.org/10.3390/math13071200.

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The Kohn–Nirenberg domains are unbounded domains in Cn. In this article, we modify the Kohn–Nirenberg domain ΩK,L=(z1,…,zn)∈Cn:Rezn+g∣zn∣2+∑j=1n−1(∣zj∣p+Kj∣zj∣p−qRezjq+Lj∣zj∣p−2qImzj2q)<0} and discuss the existence of supporting surface and peak functions at the origin.

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27

Varlioglu, Mesut, Ulrich Lienert, Jun-Sang Park, Jacob L. Jones, and Ersan Üstündag. "Thermal and Electric Field-Dependent Evolution of Domain Structures in Polycrystalline BaTiO3 Using the 3D-XRD Technique." Texture, Stress, and Microstructure 2010 (November 7, 2010): 1–10. http://dx.doi.org/10.1155/2010/910793.

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The evolution of ferroelectric domain structures inside a single grain embedded in a polycrystalline BaTiO3 ceramic was investigated under temperature and electric field using the three-dimensional X-ray diffraction (3D-XRD) method. The orientation of domains within the grain was studied during the phase transformation from the cubic to tetragonal crystal structure. The peak widths broadened from 0.10 ± 0.01∘ to 0.29±0.08∘ along the azimuthal direction during cooling. Four individual tetragonal domain structures were developed from the cubic grain. A twinning model based on {101} habit planes

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28

Xiang, Liangliang, Yaodong Gu, Ming Rong, et al. "Shock Acceleration and Attenuation during Running with Minimalist and Maximalist Shoes: A Time- and Frequency-Domain Analysis of Tibial Acceleration." Bioengineering 9, no. 7 (2022): 322. http://dx.doi.org/10.3390/bioengineering9070322.

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Tibial shock attenuation is part of the mechanism that maintains human body stabilization during running. It is crucial to understand how shock characteristics transfer from the distal to proximal joint in the lower limb. This study aims to investigate the shock acceleration and attenuation among maximalist shoes (MAXs), minimalist shoes (MINs), and conventional running shoes (CONs) in time and frequency domains. Time-domain parameters included time to peak acceleration and peak resultant acceleration, and frequency-domain parameters contained lower (3–8 Hz) and higher (9–20 Hz) frequency powe

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29

Alcelay, Ignacio, Esteban Peña, and Anas Al Omar. "Hot working behaviour and processing maps of duplex cast steel." International Journal of Materials Research 112, no. 7 (2021): 518–26. http://dx.doi.org/10.1515/ijmr-2021-8242.

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Abstract In this paper the hot working behaviour of medium carbon duplex cast steel is studied using uniaxial hot compression tests over a temperature range varying from 700 ˚C to 1 000 °C and at different strain rates ranging from 10–4 to 10–1 s–1. A model based on a variant of a dynamic materials model was employed to construct processing maps. These maps delineate the safe and unsafe domains. The safe domains, associated with dynamic recrystallization and dynamic recovery, can be chosen to optimize the hot workability of the studied material. Whereas, the unsafe domain is to be avoided beca

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30

Chen Yingkai, 陈映恺, 陈理平 Chen Liping, 郑永红 Zheng Yonghong та ін. "提高布里渊光时域反射仪频移定位精度的二次寻峰算法". Laser & Optoelectronics Progress 61, № 15 (2024): 1512003. http://dx.doi.org/10.3788/lop231978.

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31

Sha, Zhanxin, Zhaoxian Zhou, and Boyi Dai. "Analyses of Countermovement Jump Performance in Time and Frequency Domains." Journal of Human Kinetics 78, no. 1 (2021): 41–48. http://dx.doi.org/10.2478/hukin-2021-0028.

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Abstract This study aimed to analyze counter-movement jump (CMJ) performance in time and frequency domains. Fortyfour Division I American football players participated in the study. Kinetic variables were collected from both dominant and non-dominant legs using two force plates. Normalized peak power, normalized net impulse, and normalized peak force significantly correlated with jump height (r = .960, r = .998, r = .725, respectively with p < .05). The mean frequency component was significantly correlated with CMJ performance (r = .355 with p < .05). The reliability of the frequency var

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32

James, Donald T., and James K. Mortensen. "An Archean metamorphic core complex in the southern Slave Province: basement–cover structural relations between the Sleepy Dragon Complex and the Yellowknife Supergroup." Canadian Journal of Earth Sciences 29, no. 10 (1992): 2133–45. http://dx.doi.org/10.1139/e92-169.

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Archean rocks in the Fenton Lake – Brown Lake area, southern Slave Province, are subdivided into two lithotectonic domains: a supracrustal domain, which consists mainly of the Archean Yellowknife Supergroup, and a gneiss–granite domain. The latter is composed of gneissic and metaigneous rocks of the Sleepy Dragon Complex, determined to be basement to the Yellowknife Supergroup, and granite plutons, including the 2641 ± 3.5 Ma Suse Lake granite and the 2583.5 ± 1 Ma Morose Granite. Volcanic rocks of the Cameron River Belt and greywacke–mudstone turbiditic metasedimentary rocks of the Burwash Fo

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33

Hu, Chaowei, Makariy A. Tanatar, Ruslan Prozorov, and Ni Ni. "Unusual dynamic susceptibility arising from soft ferromagnetic domains in MnBi₈Te₁₃ and Sb-doped MnBi 2n Te 3n+1 (n = 2, 3)." Journal of Physics D: Applied Physics 55, no. 5 (2021): 054003. http://dx.doi.org/10.1088/1361-6463/ac3032.

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Abstract MnBi 2 n Te 3 n + 1 (MBT) is the first intrinsic magnetic topological insulator and is promising to host emergent phenomena such as quantum anomalous Hall effect. They can be made ferromagnetic by having n ⩾ 4 or with Sb doping. We studied the magnetic dynamics in a few selected ferromagnetic (FM) MBT compounds, including MnBi8Te13 and Sb doped MnBi 2 n Te 3 n + 1 ( n = 2 , 3 ) using AC susceptibility and magneto-optical imaging. Slow relaxation behavior is observed in all three compounds, suggesting its universality among FM MBT. We attribute the origin of the relaxation behavior to

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34

KARANTZENI, Irene, Carmen RUIZ, Chin-Chi LIU, and Vince J. LiCATA. "Comparative thermal denaturation of Thermus aquaticus and Escherichia coli type 1 DNA polymerases." Biochemical Journal 374, no. 3 (2003): 785–92. http://dx.doi.org/10.1042/bj20030323.

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Thermal denaturations of the type 1 DNA polymerases from Thermus aquaticus (Taq polymerase) and Escherichia coli (Pol 1) have been examined using differential scanning calorimetry and CD spectroscopy. The full-length proteins are single-polypeptide chains comprising a polymerase domain, a proofreading domain (inactive in Taq) and a 5′ nuclease domain. Removal of the 5′ nuclease domains produces the ‘large fragment’ domains of Pol 1 and Taq, termed Klenow and Klentaq respectively. Although the high temperature stability of Taq polymerase is well known, its thermal denaturation has never been di

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35

Imamura, Hiroshi, and Shinya Honda. "Cue to Acid-Induced Long-Range Conformational Changes in an Antibody Preceding Aggregation: The Structural Origins of the Subpeaks in Kratky Plots of Small-Angle X-ray Scattering." International Journal of Molecular Sciences 24, no. 15 (2023): 12042. http://dx.doi.org/10.3390/ijms241512042.

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Antibody aggregation, followed by acid denaturation and neutralization of pH, is one of the reasons why the production of therapeutic monoclonal antibodies (mAbs) is expensive. Determining the structural details of acid-denatured antibodies is important for understanding their aggregation mechanism and for antibody engineering. Recent research has shown that monoclonal antibodies of human/humanized immunoglobulin G1 (IgG1) become smaller globules at pH 2 compared to their native structure at pH 7. This acid-denatured species is unstable at pH 7 and prone to aggregation by neutralization of pH.

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36

Moysa, M. O., M. V. Talanov, K. P. Andryushin, N. A. Shvetsova, I. A. Shvetsov, and A. N. Rybyanets. "Switching processes in ferroactive solid solution 0.725NaNbO<sub>3</sub>–0.20KNbO<sub>3</sub>–0.075CdNb<sub>2</sub>O<sub>6</sub>." Известия Российской академии наук. Серия физическая 87, no. 9 (2023): 1285–88. http://dx.doi.org/10.31857/s0367676523702265.

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The results of dielectric hysteresis loops and dielectric permittivity studying of 0.725NaNbO3–0.20KNbO3–0.075CdNb2O6 ceramics in strong (5–40 kV · cm–1) and weak (0–0.3 kV · cm–1) alternating electric field are presented. The parameters of the reversible and irreversible contributions to the dielectric permittivity are determined. Based on the Preisach model, a diagram of the density of domain switching is constructed. It is shown that the distribution function of domains over local coercive fields is characterized by a sharp peak, which indicates a high degree of homogeneity of the domain st

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37

Park, Hyun-Cheol, Dat Ngo, and Sung Ho Kang. "Domain Adaptation Based on Human Feedback for Enhancing Image Denoising in Generative Models." Mathematics 13, no. 4 (2025): 598. https://doi.org/10.3390/math13040598.

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How can human feedback be effectively integrated into generative models? This study addresses this question by proposing a method to enhance image denoising and achieve domain adaptation using human feedback. Deep generative models, while achieving remarkable performance in image denoising within training domains, often fail to generalize to unseen domains. To overcome this limitation, we introduce a novel approach that fine-tunes a denoising model using human feedback without requiring labeled target data. Our experiments demonstrate a significant improvement in denoising performance. For exa

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38

Bartles, J. R., L. T. Braiterman, and A. L. Hubbard. "Endogenous and exogenous domain markers of the rat hepatocyte plasma membrane." Journal of Cell Biology 100, no. 4 (1985): 1126–38. http://dx.doi.org/10.1083/jcb.100.4.1126.

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We have used a combined biochemical and morphological approach to establish the suitability of certain endogenous and exogenous domain markers for monitoring the separation of rat hepatocyte plasma membrane domains in sucrose density gradients. As endogenous domain markers, we employed two of the integral plasma membrane protein antigens, HA 4 and CE 9, localized to the bile canalicular and sinusoidal/lateral domains, respectively, of the hepatocyte plasma membrane in rat liver tissue (Hubbard, A. L., J. R. Bartles, and L. T. Braiterman, 1985, J. Cell Biol., 100:1115-1125). We used immunoelect

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Cang, Sheng, Jiankang Chen, and Chunsheng Lu. "Evolution of the Electrical Displacement and Energy Dissipation of Lead Zirconate-Titanate Ceramics under Cyclical Load." Advances in Materials Science and Engineering 2020 (March 24, 2020): 1–12. http://dx.doi.org/10.1155/2020/6975968.

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In this paper, the electromechanical behavior of lead zirconate-titanate ceramics (P51) has been characterized and modeled. The variation of the energy dissipation and peak electrical displacement of the P51 ceramic has been investigated in details. The total strain of P51 under cyclical loading consists of elastic deformation (εije), immediate ferroelectric domain switching deformation (εijd), and time-dependent deformation (εijc). Thus, an expression for the energy dissipation of P51 can be theoretically derived. In addition, a practical method for calculating the dissipated energy has been

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40

Sy, Nguyen Chi, Ha Hoang Kha, and Nguyen Minh Hoang. "An Efficient Digital Watermarking Technique for Color Images Using Directional Transforms." Journal of Science and Technology: Issue on Information and Communications Technology 3, no. 2 (2017): 1. http://dx.doi.org/10.31130/jst.2017.57.

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This paper is concerned with a digital watermarking technique for color images based on directional transforms. Different from the traditional watermarking schemes which embed the watermarks into the spatial domain or frequency domain of the Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT), this paper investigates the performance of the watermarking schemes using the Fast Discrete Curvelet Transforms (FDCT) and Contourlet Transform (CT). We evaluate the performance of the watermarking schemes using the directional transforms on a standard database of color images in terms o

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Arshad, Madiha, Faisal Najeeb, Rameesha Khawaja, Amna Ammar, Kashif Amjad, and Hammad Omer. "Cardiac MR image reconstruction using cascaded hybrid dual domain deep learning framework." PLOS ONE 20, no. 1 (2025): e0313226. https://doi.org/10.1371/journal.pone.0313226.

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Recovering diagnostic-quality cardiac MR images from highly under-sampled data is a current research focus, particularly in addressing cardiac and respiratory motion. Techniques such as Compressed Sensing (CS) and Parallel Imaging (pMRI) have been proposed to accelerate MRI data acquisition and improve image quality. However, these methods have limitations in high spatial-resolution applications, often resulting in blurring or residual artifacts. Recently, deep learning-based techniques have gained attention for their accuracy and efficiency in image reconstruction. Deep learning-based MR imag

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Hsieh, Ping-Cheng, Po-Wen Yu, and Ming-Chang Wu. "Analytical modeling of 2D groundwater flow in a semi-infinite heterogeneous domain with variable lateral sources." AIMS Mathematics 9, no. 4 (2024): 10121–40. http://dx.doi.org/10.3934/math.2024495.

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<abstract> <p>In nature, aquifers are usually composed of distinct kinds of media, i.e., heterogeneous domains rather than homogeneous domains. Groundwater level and flow changes in such domains are more complicated than those in homogeneous domains; thus, building a mathematical model for addressing groundwater flow in heterogeneous aquifers is the present research goal. In conventional research on similar topics, many one-dimensional (1D) analytical models have been presented, but it is challenging to simulate real-world scenarios. This study develops a two-dimensional (2D) analy

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Kelele, Hailay Kiros, Mulu Bayray Kahsay, and Torbjørn Kristian Nielsen. "Dynamic Response Analysis of Wind Turbine Structure to Turbulent Wind Load: Comparative Assessment in Time and Frequency Domains." Applied Mechanics 4, no. 3 (2023): 841–55. http://dx.doi.org/10.3390/applmech4030043.

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This study investigates wind turbine structural dynamics using stochastic analysis and computational methods in both the time and frequency domains. Simulations and experiments are utilized to evaluate the dynamic response of a wind turbine structure to turbulent wind loads, with the aim of validating the results based on real wind farm conditions. Two approaches are employed to analyze the dynamic responses: the frequency domain modal analysis approach, which incorporates von Kármán spectra to represent the turbulent wind loads, and the time domain Monte Carlo simulation and Newmark methods,

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Pastur, L. A., V. V. Slavin, and A. A. Krivchikov. "Ground state of one-dimension repulsing particles on disordered lattice." International Journal of Modern Physics C 25, no. 08 (2014): 1450028. http://dx.doi.org/10.1142/s0129183114500284.

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The ground state (GS) of interacting particles on a disordered one-dimensional (1D) host-lattice is studied by a new numerical method. It is shown that if the concentration of particles is small, then even a weak disorder of the host-lattice breaks the long-range order of Generalized Wigner Crystal (GWC), replacing it by the sequence of blocks (domains) of particles with random lengths. The mean domains length as a function of the host-lattice disorder parameter is also found. It is shown that the domain structure can be detected by a weak random field, whose form is similar to that of the gro

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Kasović, Mario, Lovro Štefan, and Martin Zvonař. "More Time Spent in Sedentary Behaviors is Associated with Higher Plantar Pressures in Older Women." International Journal of Environmental Research and Public Health 17, no. 6 (2020): 2089. http://dx.doi.org/10.3390/ijerph17062089.

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Background: Although obesity has been consistently correlated with higher plantar pressure during the lifespan, to date little evidence has been provided regarding of how domain-specific and total sedentary behaviors may be correlated with plantar pressures. Moreover, high peak plantar pressures have been consistently associated with foot pain and discomfort, which prevent individuals from being physically active. Therefore, the main purpose of the study was to explore the correlations between time spent in sedentary behaviors and plantar pressures. Methods: We recruited 120 older women aged ≥

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Yamani, Lama, Mathieu Latreille та Louise Larose. "Interaction of Nck1 and PERK phosphorylated at Y561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content". Molecular Biology of the Cell 25, № 5 (2014): 702–11. http://dx.doi.org/10.1091/mbc.e13-09-0511.

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PERK, the PKR-like endoplasmic reticulum (ER) kinase, is an ER transmembrane serine/threonine protein kinase activated during ER stress. In this study, we provide evidence that the Src-homology domain–containing adaptor Nck1 negatively regulates PERK. We show that Nck directly binds to phosphorylated Y561 in the PERK juxtamembrane domain through its SH2 domain. We demonstrate that mutation of Y561 to a nonphosphorylatable residue (Y561F) promotes PERK activity, suggesting that PERK phosphorylation at Y561 (pY561PERK) negatively regulates PERK. In agreement, we show that pY561PERK delays PERK a

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Goldschen-Ohm, Marcel P., Alexander Haroldson, Mathew V. Jones, and Robert A. Pearce. "A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors." Journal of General Physiology 144, no. 1 (2014): 27–39. http://dx.doi.org/10.1085/jgp.201411183.

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Ion channels, like many other proteins, are composed of multiple structural domains. A stimulus that impinges on one domain, such as binding of a ligand to its recognition site, can influence the activity of another domain, such as a transmembrane channel gate, through interdomain interactions. Kinetic schemes that describe the function of interacting domains typically incorporate a minimal number of states and transitions, and do not explicitly model interactions between domains. Here, we develop a kinetic model of the GABAA receptor, a ligand-gated ion channel modulated by numerous compounds

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Edigarian, Armen. "Peak points for domains in Cn." Annales Polonici Mathematici 114, no. 1 (2015): 1–12. http://dx.doi.org/10.4064/ap114-1-1.

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Iordan, Andrei. "Peak sets in weakly pseudoconvex domains." Mathematische Zeitschrift 188, no. 2 (1985): 171–88. http://dx.doi.org/10.1007/bf01304206.

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Liang, Li, Wanxiu Ai, Xiaodan Yang, and Luqiang Zhao. "Research on the Terrain Characteristics of Changbai Mountain and Their Impact on Precipitation and Wind Distribution." Atmosphere 15, no. 3 (2024): 272. http://dx.doi.org/10.3390/atmos15030272.

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The terrain of Changbai Mountain has great influence on the distribution of atmospheric flows and the occurrence and development of precipitation. However, quantitative studies on the real terrain characteristics and the terrain effect on precipitation distribution in this region are scant at present. This study quantitatively analyzes the regional characteristic of topographic perturbations and the relationship between terrain, wind, and precipitation in Changbai Mountain region by using a spectral analysis of the two-dimensional discrete cosine transform. Three domains with relatively heavy

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