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Dissertations / Theses on the topic 'Peyers patches'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Da, Silva Clément. "Fonction des phagocytes de la plaque de Peyer dans la réponse immunitaire mucosale." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0251.

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Nous avons mis en évidence la présence des phagocytes exprimant le lysozyme dans les Plaque de Peyer chez l’Homme et montré que, comme chez la souris, elles sont principalement localisées dans le SED et sont distinctes des cDC. Dans un deuxième temps, nous avons étudié dans les PP de souris la fonction des différentes populations de phagocytes nouvellement caractérisées. Nous avons en particulier étudié l’impact de la détection d’un acide nucléique d’origine virale par les phagocytes en utilisant un agoniste synthétique du TLR7 : le R848. Bien que TLR7 soit exprimé par les cellules dérivées de

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2

Kiriya, Keiichi. "Essential role of Peyer's patches in the development of Helicobacter-induced gastritis." Kyoto University, 2007. http://hdl.handle.net/2433/135719.

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3

Pullen, A. M. "Studies on Peyer's patch T cell hybridomas." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233317.

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The initial objective of this thesis was to generate Peyer's patch T cell hybridomas producing lymphokines that regulate IgA-secreting B lymphocytes. Unprimed Peyer's patch cells were fused with BW5147. Karyotype analysis and fluorescent staining of the thy-1.2 marker confirmed the generation of hybridomas. It was envisaged that these hybridomas would be tested for their effects on IgA production by LPS-stimulated B cells. However, when the panel of hybridomas was available for testing there were technical difficulties with this assay. Sendai virus-primed Peyer's patch T cells were used in a s

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4

Meynell, Helen Mary. "Bacterial modulation of particle transport across the follicle-associated epithelium of Peyer's patches." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285656.

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5

Hashi, Hiroyuki. "Compartmentalization of Peyer's Patch Anlagen before Lymphocyte Entry." Kyoto University, 2001. http://hdl.handle.net/2433/150171.

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6

Okuda, Masato. "Distinct activities of stromal cells involved in the organogenesis of lymph nodes and Peyer's patches." Kyoto University, 2007. http://hdl.handle.net/2433/135782.

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7

Sansom, Nigel P. "Antigen sampling by porcine intestinal Peyer's patch M-cells." Thesis, University of Aberdeen, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322637.

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8

Makala, Levi Hakwale Chikondo. "Isolation and characterization of pig peyer's patch dendritic cells." Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336826.

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9

Kawamoto, Shimpei. "Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches." Kyoto University, 2011. http://hdl.handle.net/2433/142110.

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10

Adachi, Satoko. "Three distinctive steps in Peyer's patch formation of murine embryo." Kyoto University, 1997. http://hdl.handle.net/2433/202198.

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11

Drayson, M. T. "The influence of the interdigitating cell on the microenvironment of the spleen, lymph nodes and Peyer's patches." Thesis, University of Manchester, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383873.

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12

Bonnardel, Johnny. "Caractérisation phénotypique, ontogénique et fonctionnelle du système phagocytaire mononucléé des plaques de Peyer." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4048.

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Les plaques de Peyer (PP) sont les principaux sites inducteurs de la réponse immunitaire mucosale.L’épithélium associé aux follicules comprend des cellules épithéliales spécifiques, appelées cellules M et spécialisées dans le transport du matériel présent dans la lumière intestinale vers le dôme sous épithélial (SED) où il sera pris en charge par les cellules du système phagocytaire mononuclée (MPS) qui orchestreront ensuite les réponses immunitaires mucosales.Nous avons effectué une analyse complète du phénotype, de la distribution, de l’ontogénie, de la fonction et des profils transcriptomiq

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13

Honda, Kenya. "Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis." Kyoto University, 2001. http://hdl.handle.net/2433/150560.

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14

Sánchez, Quintero Alejandra. "Effect of congruent gastro-intestinal pathogen infection on oral prion disease susceptibility." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33225.

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Transmissible spongiform encephalopathies (TSEs) or prion diseases, are subacute neurodegenerative diseases that infect humans and animals. Many of these diseases are acquired by peripheral exposure (e.g. orally). After oral exposure prion replication within the Peyer's patches (PP) in the small intestine is necessary for the efficient spread of the disease to the brain. Within the intestine, bacteria and pathogenic microorganisms can affect the status of the gut associated lymphoid tissue (GALT). GALT consists of PP and isolated lymphoid follicles (ILF) that maintain homeostasis and protect f

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15

Gullberg, Elisabet. "Particle Transcytosis Across the Human Intestinal Epithelium : Model Development and Target Identification for Improved Drug Delivery." Doctoral thesis, Uppsala University, Department of Pharmacy, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4780.

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<p>The use of nano- and micro-particulate carriers as delivery systems for oral vaccines has been under investigation for several decades. Surprisingly little is known of their uptake in the human intestine, despite the fact that substantial improvement is required to achieve adequate immune responses in man after oral administration. </p><p>In this thesis, various aspects of particle transcytosis across the human intestinal epithelium were studied, in order to identify strategies for improved uptake of nano- and micro-particulate drug delivery systems. </p><p>The follicle associated epitheliu

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16

Andersen, Jacqueline Kirsti. "The pig Ileal Peyer's patch : a discrete and readily accessible system to study the control of apoptosis in immature b-cells." Thesis, University of Hertfordshire, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267477.

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17

Ramos, Orivaldo Pereira [UNESP]. "Influência das células dendríticas das placas de peyer na modulação das repostas Th1/Th2 em camundongos infectados com Yersinia pseudotuberculosis." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/103336.

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Made available in DSpace on 2014-06-11T19:32:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-01-20Bitstream added on 2014-06-13T21:04:28Z : No. of bitstreams: 1 ramos_op_dr_arafcf.pdf: 948525 bytes, checksum: 0581866624e7c3f57ffffca838856184 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Yersinia pseudotuberculosis e Y. enterocolitica são patógenos que causam desordens gastrintestinais. Estudos utilizando infecção in vitro demonstraram que Y. enterocolitica pode ter como alvo as células dendríticas (DCs), afetando várias de suas funções, incluindo sua mat

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18

Ramos, Orivaldo Pereira. "Influência das células dendríticas das placas de peyer na modulação das repostas Th1/Th2 em camundongos infectados com Yersinia pseudotuberculosis /." Araraquara : [s.n.], 2009. http://hdl.handle.net/11449/103336.

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Orientador: Beatriz Maria Machado de Medeiros<br>Banca: Beatriz Maria Machado de Medeiros<br>Banca: Maria Terezinha Serrão Peraçoli<br>Banca: Iracilda Zeppone Carlos<br>Banca: Cleni Mara Marzocchi Machado<br>Banca: Fernanda de Freitas Anibal<br>Resumo: Yersinia pseudotuberculosis e Y. enterocolitica são patógenos que causam desordens gastrintestinais. Estudos utilizando infecção in vitro demonstraram que Y. enterocolitica pode ter como alvo as células dendríticas (DCs), afetando várias de suas funções, incluindo sua maturação e produção de citocinas, e, conseqüentemente, contribuindo para a di

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19

David, Christian Walfried. "Cell proliferation, apoptosis, and B- and T-Lamphocytes in Peyer's patches of the ileum, in thymus and in lymphnodes of pre-term calves and in full-term calves at birth and on Day 5 of life /." [S.l.] : [s.n.], 2003. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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20

Hays, Constantin. "Influence de l'imprégnation hormonale périnatale sur la virulence du Streptocoque du groupe B Perinatal hormonal concentrations favor CC17 group B Streptococcus hypervirulence and intestinal translocation through M cells." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2183&f=15494.

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Streptococcus agalactiae (streptocoque du groupe B, SGB) représente la première cause d'infections néonatales bactériennes invasives pour lesquelles on définit deux syndromes, un syndrome précoce (SP, 1ère semaine de vie) et un syndrome tardif (ST, 7 à 89 jours après la naissance). Le SP se manifeste par une pneumonie associée ou non à une bactériémie et résulte de l'inhalation par le nouveau-né de sécrétions vaginales ou de liquide amniotique contaminés par le SGB. Le ST se déclare par une septicémie dont la porte d'entrée serait le tractus gastro-intestinal et est caractérisé par un fort tau

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21

Salim, Sa'ad Yislam. "Mucosal dendritic cells in inflammatory bowel disease." Doctoral thesis, Linköpings universitet, Kirurgi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-52234.

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Crohn's disease, a chronic inflammation of the bowel, is a multi-factorial condition where uncontrolled immune responses to luminal bacteria occur in genetically predisposed individuals. The first observable clinical signs are small ulcers that form at a specialised form of epithelium, follicle-associated epithelium (FAB). The FAB covers immune inductive sites, Peyer's patches, which function primarily as sensory areas that sample the externaI gut environment. Dendritic cells are one of the key cells that are involved in sensing luminal contents and orchestrating the gut immune system. The mai

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22

Jarry, Anne. "Tissu lymphoide du tube digestif humain normal et pathologique : relations entre les cellules lymphoides et les cellules epitheliales dans le tube digestif humain et les plaques de peyer de rat." Paris 6, 1987. http://www.theses.fr/1987PA066443.

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23

Keita, Åsa. "Barrier function of the Follicle-Associated Epithelium in Stress and Crohn's disease." Doctoral thesis, Linköpings universitet, Kirurgi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-9271.

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Crohns sjukdom är en kronisk inflammatorisk tarmsjukdom av okänd orsak. Det tidigaste tecknet på Crohns sjukdom är mikroskopiska sår i det s.k. follikelassocierade epitelet (FAE) som täcker ansamlingar av immunceller i tarmen. FAE är specialiserat för att fånga innehåll från tarmen och transportera det till underliggande immunvävnad. Denna funktion är viktig för att inducera skyddande immunsvar, men den utgör också en ingångsväg för sjukdomsalstrande bakterier. Crohns sjukdom är associerat med ett kraftigt ökat immunsvar mot bakterier, och sjukdomsförloppet kan ändras av stress. Det övergripan

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24

"REGULATORY B CELLS IN THE JEJUNAL PEYER’S PATCHES OF BOVINE AND SHEEP." Thesis, 2014. http://hdl.handle.net/10388/ETD-2014-09-1731.

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Toll-like receptors (TLRs) recognize microbial components as danger signals and induce immune responses. TLR’s are expressed in many tissues of the host that are involved in immune responses including the intestines where they are abundantly expressed. This situation presents a challenge in the gastrointestinal tract which is constantly exposed to a wide variety of commensal organisms. Therefore, innate immune recognition in the intestine must be tightly regulated to prevent unwanted inflammation against harmless commensal micro-organisms and yet allow for the induction of protective immunity

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25

LI, CHUANG HSIAO, and 莊曉莉. "Physiological Significance of Dietary Fiber on Intestine Epithelium Mucosal Lymphoid Tissue-Peyer's Patches." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/83098560506350419837.

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碩士<br>中國文化大學<br>生物科技研究所<br>89<br>Modulation of intestinal immune function related to mesenteric lymph node by dietary fiber had been studied recently. In order to investigate the physiological roles of dietary fiber on intestine epithelium mucosal lymphoid tissue-peyer's patches (PP), 3-week-old male Wistar rats were fed with 8-week cellulose (5 and 10g/100g diet), rice bran (10 g/100 g diet), and wheat bran (10g/ 100g diet) as well as without any dietary fiber supplement as a control group. Plasma samples and secretory IgA of intestinal mucus were drawn for quantity of immunological proteins

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26

Juan, Li-Hui, and 阮麗慧. "The Effect of Dietary Fiber on Intestine Epithelium Mucosal Lymphoid Tissue-Peyer’s Patches." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/89342668925793494776.

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碩士<br>中國文化大學<br>生活應用科學研究所<br>88<br>According to the study on dietary fiber intake for Taiwanese, only half amount of daily recommended allowance had been taken. Epidemiological investigation also demonstrated that dietary fiber plays an important role in the prevention of colon cancer. Since the gut-associated lymphoid tissue（GALT）-peyer’s patches of the epithelium mucosal cells is the primary defense system of the intestine against the foreign antigen, we wonder if dietary fiber affects the development of GALT and then further affects the intestinal immunity. Three-to-four-week-o

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27

Chen, Sui-Han, and 陳綏涵. "The Study of Proliferation and Immune Response of Peyer’s-Patches’ Lymphocytes Induced by Dietary Fiber." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/61063817159789794588.

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碩士<br>中國文化大學<br>生物科技研究所<br>93<br>Dietary fiber can modulate in the growth and distribution of fungus in intestinal tract function well. Peyer’s patches are the kind of lymph nodes that are the first contacted by food molecules after ingestion. May dietary fiber stimulate the proliferation of Peyer’s patches’ lymphocytes and regulate the immune response？ The purpose of this study is proliferation and immune response of Peyer’s patches’ lymphocytes in Wistar male rats treated with different types and proportion of dietary fiber. Wistar rats were divided in to 5 groups that were treated with 5% (

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28

Alitheen, Noorjahan Mohamed. "An in vitro model of B lymphocyte development in the Peyer's patches of fetal lambs." Phd thesis, 2001. http://hdl.handle.net/1885/144959.

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29

Kárová, Kristýna. "Studium populací lymfocytů v tenkém střevu prasete." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-305767.

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8 ABSTRACT Historically pig is allocated to a group of animals which use certain parts of their small intestine to acquire a fully developed primary B cell reperoire. Development of such primary repertoire is independent on the antigen presence and resembles the primary lymphopoietic activity of avian bursa of Fabricius. However, some findings concernig the pig's alignment in the above mentioned group suggest otherwise. This graduation thesis is focused on the investigtion of lymphocyte populations and subpopulations in the small intestine of germ-free and conventional piglets. The aim is to d

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30

Štěpánová, Kateřina. "Vývoj B buněk u prasat a úloha gama delta T lymfocytů při imunizaci naivního imunitního systému." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-328683.

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Thesis summary The process of B cell lymphogenesis in swine remains uncertain. Some reports indicate that pigs belong to a group of animal that use ileal Peyers's patches (IPP) for the generation of B cells while others point to the possibility that the bone marrow is functional throughout life. The functional subpopulations of B cells in swine are also unknown. Together with other ruminants, and also birds, γδ T cells in swine may account for >70% of all T cells which is in apparent contrast with humans and mice. The purpose of this thesis was to address these discrepancies and unresolved iss

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