Log in

Relevant bibliographies by topics / PFP model / Journal articles

To see the other types of publications on this topic, follow the link: PFP model.

Journal articles on the topic 'PFP model'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'PFP model.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Street, Shayna E. A., Erika Cretney та Mark J. Smyth. "Perforin and interferon-γ activities independently control tumor initiation, growth, and metastasis". Blood 97, № 1 (2001): 192–97. http://dx.doi.org/10.1182/blood.v97.1.192.

Full text

Abstract:

Abstract Perforin (pfp) and interferon-γ (IFN-γ) together in C57BL/6 (B6) and BALB/c mouse strains provided optimal protection in 3 separate tumor models controlled by innate immunity. Using experimental (B6, RM-1 prostate carcinoma) and spontaneous (BALB/c, DA3 mammary carcinoma) models of metastatic cancer, mice deficient in both pfp and IFN-γ were significantly less proficient than pfp- or IFN-γ–deficient mice in preventing metastasis of tumor cells to the lung. Pfp and IFN-γ–deficient mice were as susceptible as mice depleted of natural killer (NK) cells in both tumor metastasis models, an

APA, Harvard, Vancouver, ISO, and other styles

2

Sánchez-Hernández, Juan P., Juan Frausto-Solís, Juan J. González-Barbosa, Diego A. Soto-Monterrubio, Fanny G. Maldonado-Nava, and Guadalupe Castilla-Valdez. "A Peptides Prediction Methodology for Tertiary Structure Based on Simulated Annealing." Mathematical and Computational Applications 26, no. 2 (2021): 39. http://dx.doi.org/10.3390/mca26020039.

Full text

Abstract:

The Protein Folding Problem (PFP) is a big challenge that has remained unsolved for more than fifty years. This problem consists of obtaining the tertiary structure or Native Structure (NS) of a protein knowing its amino acid sequence. The computational methodologies applied to this problem are classified into two groups, known as Template-Based Modeling (TBM) and ab initio models. In the latter methodology, only information from the primary structure of the target protein is used. In the literature, Hybrid Simulated Annealing (HSA) algorithms are among the best ab initio algorithms for PFP; G

APA, Harvard, Vancouver, ISO, and other styles

3

Zhang, Peng Wei, Qing Bo Wen, and Li Ming Hu. "Numerical Simulation of Contaminant Dynamic Transfer in Dual-Domain Model." Advanced Materials Research 864-867 (December 2013): 1379–85. http://dx.doi.org/10.4028/www.scientific.net/amr.864-867.1379.

Full text

Abstract:

Preferential flowpaths (PFP) causes highly heterogeneity of soil. In this study a preferential flowpaths generalized model has been established, based on dual-domain model (DDM) which reflects contaminant transport and the dynamic transfer between mobile and immobile domains, quantitatively analyses the contaminant mass transfer in pore scale at three different conditions. Besides, define relative hydraulic conductivity reflect the impact of PFP physical parameters, results show that it can affect the contaminant transport form and the distribution of contaminant concentration.

APA, Harvard, Vancouver, ISO, and other styles

4

Raftis, Jennifer, Andrew Lucking, Amanda Hunter, et al. "Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury." Thrombosis and Haemostasis 108, no. 07 (2012): 176–82. http://dx.doi.org/10.1160/th12-02-0059.

Full text

Abstract:

SummaryPlatelets are the principal component of the innate haemostatic system that protect from traumatic bleeding. We investigated whether lyophilised human platelets (LHPs) could enhance clot formation within platelet-free and whole blood environments using an ex vivo model of deep arterial injury. Lyophilised human platelets were produced from stored human platelets and characterised using conventional, fluorescent and electron microscopic techniques. LHPs were resuspended in platelet-free plasma (PFP) obtained from citrated whole human blood to form final concentrations of 0,20 and 200 × 1

APA, Harvard, Vancouver, ISO, and other styles

5

Myer, Gregory D., Kevin R. Ford, Kim D. Barber Foss, Mitchell J. Rauh, Mark V. Paterno, and Timothy E. Hewett. "A Predictive Model to Estimate Knee-Abduction Moment: Implications for Development of a Clinically Applicable Patellofemoral Pain Screening Tool in Female Athletes." Journal of Athletic Training 49, no. 3 (2014): 389–98. http://dx.doi.org/10.4085/1062-6050-49.2.17.

Full text

Abstract:

Context: Prospective measures of high external knee-abduction moment (KAM) during landing identify female athletes at increased risk of patellofemoral pain (PFP). A clinically applicable screening protocol is needed. Objective: To identify biomechanical laboratory measures that would accurately quantify KAM loads during landing that predict increased risk of PFP in female athletes and clinical correlates to laboratory-based measures of increased KAM status for use in a clinical PFP injury-risk prediction algorithm. We hypothesized that we could identify clinical correlates that combine to accu

APA, Harvard, Vancouver, ISO, and other styles

6

Radovic, Ivona, Nikola Grozdanic, Bojan Djordjevic, Slobodan Serbanovic, and Mirjana Kijevcanin. "Prediction of excess molar volumes of binary mixtures by Prigogine-Flory-Patterson (PFP) and extended real association solution (ERAS) models." Journal of the Serbian Chemical Society 82, no. 12 (2017): 1379–90. http://dx.doi.org/10.2298/jsc170817103r.

Full text

Abstract:

In this paper, the Prigogine?Flory?Patterson (PFP) theoretical model and the extended real association solution (ERAS) model for the prediction of the excess molar volumes of 17 binary sets of alcohols (methanol, ethanol, propan-1-ol, butan-1-ol, butan-2-ol and pentan-1-ol) with benzene, chlorobenzene, acetonitrile, hexan-1-amine and n-heptane were tested at 298.15 K and atmospheric pressure. The binary sets contained 333 experimental data points for 11 different compounds. The ERAS model demonstrated better correlative characteristics for binary mixtures comparing to PFP model. The ERAS model

APA, Harvard, Vancouver, ISO, and other styles

7

Chen, Yu-Jen, and Christopher M. Powers. "Comparison of Three-Dimensional Patellofemoral Joint Reaction Forces in Persons With and Without Patellofemoral Pain." Journal of Applied Biomechanics 30, no. 4 (2014): 493–500. http://dx.doi.org/10.1123/jab.2011-0250.

Full text

Abstract:

The purpose of this study was to determine if persons with patellofemoral pain (PFP) exhibit differences in patellofemoral joint reaction forces (PFJRFs) during functional activities. Forty females (20 PFP, 20 controls) underwent two phases of data collection: (1) magnetic resonance imaging (MRI) and (2) biomechanical analysis during walking, running, stair ascent, and stair descent. A previously described three-dimensional model was used to estimate PFJRFs. Resultant PFJRFs and the orthogonal components were reported. The PFP group demonstrated lower peak resultant PFJRFs and posterior compon

APA, Harvard, Vancouver, ISO, and other styles

8

Rehman, Sidra, Hafiz Muhammad Shahrukh, Ayesha Mansha Virk, and Dr Mattiullah Butt. "Pay for Performance (Pfp) Increasing Creativity Through Intrinsic Motivation." International Journal of Research in Business and Social Science (2147-4478) 8, no. 2 (2019): 74–90. http://dx.doi.org/10.20525/ijrbs.v8i2.190.

Full text

Abstract:

Supervisor enhances their subordinates’ level of creativity to provide the latest insights into intrinsic motivation. Therefore, demonstrating the other site in which pay for performance decisions are controlled by the HR department through individual interaction with increasing (PFP) pay for performance and employee creativity (CR). By utilizing the sample size of 250 questionnaires out of which 206 were completed from Lahore, the city of Pakistan. We establish that the consequence of (PFP) on creativity was invariantly mediating by intrinsic motivation in such a way that both mediator or mod

APA, Harvard, Vancouver, ISO, and other styles

9

Liao, Tzu-Chieh, Joyce H. Keyak, and Christopher M. Powers. "Runners With Patellofemoral Pain Exhibit Greater Peak Patella Cartilage Stress Compared With Pain-Free Runners." Journal of Applied Biomechanics 34, no. 4 (2018): 298–305. http://dx.doi.org/10.1123/jab.2017-0229.

Full text

Abstract:

The primary purpose of this study is to determine whether recreational runners with patellofemoral pain (PFP) exhibit greater peak patella cartilage stress compared with pain-free runners. A secondary purpose was to determine the kinematic and/or kinetic predictors of peak patella cartilage stress during running. A total of 22 female recreational runners (12 with PFP and 10 pain-free controls) participated in this study. Patella cartilage stress profiles were quantified using subject-specific finite element models simulating the maximum knee flexion angle during the stance phase of running. In

APA, Harvard, Vancouver, ISO, and other styles

10

Joshi, Nikhil Vilas, Jennifer Raftis, AJ Lucking, et al. "Thrombosomes Show Dose-Dependent Increase in Thrombus Formation in a Model of Deep Arterial Injury." Blood 118, no. 21 (2011): 2319. http://dx.doi.org/10.1182/blood.v118.21.2319.2319.

Full text

Abstract:

Abstract Abstract 2319 Introduction Thrombosomes are novel lyophilized human platelet derivatives that retain a number of key platelet structural and functional properties. Building on preliminary in vitro studies, we here sought to investigate whether Thrombosomes, suspended in platelet free plasma (PFP), would enhance and be incorporated in thrombus generated under flow conditions within a validated and well-characterised model of deep arterial injury. Methods PFP was obtained by centrifuging citrated whole blood from six healthy non-smoking volunteers and filtering with a 0.22μm filter. Thr

APA, Harvard, Vancouver, ISO, and other styles

11

Jinsui, Yu, Situ Bing, Luo Muhua, et al. "Carboxymethyl-hexanoyl Chitosan Nanodroplets for Ultrasonic Imaging and Drug Delivery to Tumor." Current Pharmaceutical Design 24, no. 15 (2018): 1682–88. http://dx.doi.org/10.2174/1381612824666180515122836.

Full text

Abstract:

Introduction: Although a great many strategies have been proposed for tumor-targeted chemotherapy, current delivery methods of anticancer drugs present limited success with inevitable systemic toxicity. The aim of this study was to develop a new kind of theranostic carrier for targeted tumor therapy. Methods: Prior to prepare CHC-PFP-DOX, carboxymethyl-hexanoyl chitosan (CHC) was synthesized by acylation of carboxymethyl chitosan. To develop CHC-PFP, perfluoropentane (PFP), an ultrasound gas precursor, was simultaneously encapsulated into the hydrophobic inner cores of pre-formulated CHC micel

APA, Harvard, Vancouver, ISO, and other styles

12

Maclachlan, Liam R., Mark Matthews, Paul W. Hodges, Natalie J. Collins, and Bill Vicenzino. "The psychological features of patellofemoral pain: a cross-sectional study." Scandinavian Journal of Pain 18, no. 2 (2018): 261–71. http://dx.doi.org/10.1515/sjpain-2018-0025.

Full text

Abstract:

Abstract Background and aims: Patellofemoral pain (PFP) is a prevalent and debilitating musculoskeletal condition, considered to have a mechanical aetiology. As such, the physical impairments associated with PFP are well documented and have helped characterise different physical phenotypes. But little is known about the relationship between PFP and psychological well-being. In this study, we aimed to: (1) compare psychological profiles between groups with and without PFP; (2) compare psychological profiles and condition severity between PFP subgroups; and (3) explore relationships between psyc

APA, Harvard, Vancouver, ISO, and other styles

13

Bartholomew, Clare, Laura Edwards, and Simon Lack. "Pressure pain thresholds in adults with patellofemoral pain and patellofemoral joint osteoarthritis: a case-control study." Scandinavian Journal of Pain 19, no. 4 (2019): 713–23. http://dx.doi.org/10.1515/sjpain-2019-0026.

Full text

Abstract:

Abstract Background and aims Patellofemoral pain (PFP) and patellofemoral joint osteoarthritis (PFJOA) are common non-self-limiting conditions causing significant pain and disability. The underlying pain pathologies lack consensus with evidence suggesting reduced pressure pain thresholds (PPTs) in adolescent females with PFP and individuals with knee osteoarthritis. A paucity of evidence exists for mixed-sex adults with PFP and PFJOA in isolation. Exploring if pain sensitisation is a dominant feature of PFP and PFJOA may have important implications for the delivery of a patient centred managem

APA, Harvard, Vancouver, ISO, and other styles

14

II, Randolph Stone, John T. Wall, Shanmugasundaram Natesan, and Robert J. Christy. "PEG-Plasma Hydrogels Increase Epithelialization Using a Human Ex Vivo Skin Model." International Journal of Molecular Sciences 19, no. 10 (2018): 3156. http://dx.doi.org/10.3390/ijms19103156.

Full text

Abstract:

In vitro cell culture methods are used extensively to study cellular migration, proliferation, and differentiation, which play major roles in wound healing but the results often do not translate to the in vivo environment. One alternative would be to establish an ex vivo model utilizing human discarded skin to evaluate therapies in a more natural setting. The purpose of this study was to institute such a model by creating ‘wounds’ in the center of a piece of discarded skin and treating them with three different biomaterials: collagen, polyethylene glycol (PEG)-fibrin, or PEG-platelet free plas

APA, Harvard, Vancouver, ISO, and other styles

15

Schwane, Brandi G., Benjamin M. Goerger, Shiho Goto, J. Troy Blackburn, Alain J. Aguilar, and Darin A. Padua. "Trunk and Lower Extremity Kinematics During Stair Descent in Women With or Without Patellofemoral Pain." Journal of Athletic Training 50, no. 7 (2015): 704–12. http://dx.doi.org/10.4085/1062-6050-49.3.100.

Full text

Abstract:

Context There is limited evidence indicating the contribution of trunk kinematics to patellofemoral pain (PFP). A better understanding of the interaction between trunk and lower extremity kinematics in this population may provide new avenues for interventions to treat PFP. Objective To compare trunk and lower extremity kinematics between participants with PFP and healthy controls during a stair-descent task. Design Cross-sectional study. Setting Research laboratory. Patients or Other Participants Twenty women with PFP (age = 22.2 ± 3.1 years, height = 164.5 ± 9.2 cm, mass = 63.5 ± 13.6 kg) and

APA, Harvard, Vancouver, ISO, and other styles

16

Lu, Yuzhong, Zengrui Tian, Guillermo Andres Buitrago, Shuiwen Gao, Yuanjun Zhao, and Shuai Zhang. "Intellectual Capital and Firm Performance in the Context of Venture-Capital Syndication Background in China." Complexity 2021 (March 26, 2021): 1–17. http://dx.doi.org/10.1155/2021/3425725.

Full text

Abstract:

This paper is intended to investigate the role of Venture-Capital Syndication (VCS) background in the relationship between intellectual capital (IC) and portfolio firm performance (PFP); specifically, this article examines the moderating effect of VCS’s leading firm background and member heterogeneity on the effect of IC on PFP. This study used a modified VAIC model to measure IC to compose a 4-component variable including human capital, structural capital, relational capital, and innovation capital. The data were collected from VCS-backed and listed firms in China during 2014 to 2018 applying

APA, Harvard, Vancouver, ISO, and other styles

17

Zhang, Yong, Lirong Long, and Junwei Zhang. "Pay for performance and employee creativity." Management Decision 53, no. 7 (2015): 1378–97. http://dx.doi.org/10.1108/md-11-2013-0596.

Full text

Abstract:

Purpose – Previous studies concerning on the effect of reward on individual creativity have generated generally inconsistent conclusions. These ambiguities call for more studies to explore the potential boundary conditions under which reward may or may not promote creativity. The purpose of this paper is to clarify how pay for performance (PFP), a specific type of extrinsic reward awarded in field settings, impacts employees’ creative self-efficacy, and their creativity under varying levels of procedural justice as well as willingness to take risks. Design/methodology/approach – This study use

APA, Harvard, Vancouver, ISO, and other styles

18

Muenich, Rebecca Logsdon, Margaret M. Kalcic, Jonathan Winsten, et al. "Pay-for-Performance Conservation Using SWAT Highlights Need for Field-Level Agricultural Conservation." Transactions of the ASABE 60, no. 6 (2017): 1925–37. http://dx.doi.org/10.13031/trans.12379.

Full text

Abstract:

Abstract. Pay-for-performance (PFP) is a relatively new approach to agricultural conservation that attaches an incentive payment to quantified reductions in nutrient runoff from a participating farm. Similar to a payment for ecosystem services approach, PFP lends itself to providing incentives for the most beneficial practices at the field level. To date, PFP conservation in the U.S. has only been applied in small pilot programs. Because monitoring conservation performance for each field enrolled in a program would be cost-prohibitive, field-level modeling can provide cost-effective estimates

APA, Harvard, Vancouver, ISO, and other styles

19

Cress, M. Elaine, and Mary Meyer. "Maximal Voluntary and Functional Performance Needed for Independence in Adults Aged 65 to 97 Years." Physical Therapy 83, no. 1 (2003): 37–48. http://dx.doi.org/10.1093/ptj/83.1.37.

Full text

Abstract:

Abstract Background and Purpose. Age-related loss of muscle mass and cardiovascular endurance can lead to impairments in muscle force production and cardiac function that, in turn, limit performance in activities essential to everyday living. The purposes of this study were: (1) to identify the “breakpoint” or threshold of maximal voluntary performance and performance in ordinary daily function (2) to evaluate the predictive validity of the threshold to identify the ability independently without self-reported functional limitation. Subjects and Methods. Men and women (N=192; mean age=76 years,

APA, Harvard, Vancouver, ISO, and other styles

20

Yang, Bo, Hai Zhao, Jun Zhang, Si Yuan Jia, Yi Wen Liu, and Wen Liu. "Small Fluctuations Research of Internet AS-Level Topology Based on PFP Model." Advanced Materials Research 712-715 (June 2013): 2635–38. http://dx.doi.org/10.4028/www.scientific.net/amr.712-715.2635.

Full text

Abstract:

In order to highlight small fluctuation characteristics of the mutation evolution, this paper by adding periodic function, and use the actual data fitting Internet with Ark to obtain the new attachment to improve PFP model priority set point formula. Simulation results show that the model not only keeps power law, but also better reflects small fluctuation characteristics of the Internet AS-level topology. The dynamic modeling algorithm can reconfigure the evolution of the Internet.

APA, Harvard, Vancouver, ISO, and other styles

21

Mahapatra, Mousumi Singha, Jayasree Raveendran, and Anupam De. "Building a Model on Influence of Behavioural and Cognitive Factors on Personal Financial Planning: A Study Among Indian Households." Global Business Review 20, no. 4 (2019): 996–1009. http://dx.doi.org/10.1177/0972150919844897.

Full text

Abstract:

Personal financial planning is an emerging area of interest, given the complexities and risks involved in investments and financial markets. As an extension to studies in the field of cognitive and behavioural decision theories, the role of financial cognition (FC) and mental accounting (MA) is examined as antecedents to personal financial planning (PFP) of Indian households and established as a model to represent the same. The study considers factors, that is, financial attitude (FA), risk attitude (RA) and financial knowledge (FK), to measure FC and uses the components of mental budgeting (M

APA, Harvard, Vancouver, ISO, and other styles

22

Yan, James J., Thomas Kroll, Michael L. Baker, et al. "Resonant inelastic X-ray scattering determination of the electronic structure of oxyhemoglobin and its model complex." Proceedings of the National Academy of Sciences 116, no. 8 (2019): 2854–59. http://dx.doi.org/10.1073/pnas.1815981116.

Full text

Abstract:

Hemoglobin and myoglobin are oxygen-binding proteins with S = 0 heme {FeO2}8active sites. The electronic structure of these sites has been the subject of much debate. This study utilizes Fe K-edge X-ray absorption spectroscopy (XAS) and 1s2p resonant inelastic X-ray scattering (RIXS) to study oxyhemoglobin and a related heme {FeO2}8model compound, [(pfp)Fe(1-MeIm)(O2)] (pfp = meso-tetra(α,α,α,α-o-pivalamido-phenyl)porphyrin, or TpivPP, 1-MeIm = 1-methylimidazole) (pfpO2), which was previously analyzed using L-edge XAS. The K-edge XAS and RIXS data of pfpO2and oxyhemoglobin are compared with th

APA, Harvard, Vancouver, ISO, and other styles

23

Schmaltz, Cornelius, Onder Alpdogan, Kirsten J. Horndasch, et al. "Differential use of Fas ligand and perforin cytotoxic pathways by donor T cells in graft-versus-host disease and graft-versus-leukemia effect." Blood 97, no. 9 (2001): 2886–95. http://dx.doi.org/10.1182/blood.v97.9.2886.

Full text

Abstract:

Abstract In allogeneic bone marrow transplantation (BMT) donor T cells are primarily responsible for antihost activity, resulting in graft-versus-host disease (GVHD), and for antileukemia activity, resulting in the graft-versus-leukemia (GVL) effect. The relative contributions of the Fas ligand (FasL) and perforin cytotoxic pathways in GVHD and GVL activity were studied by using FasL-defective or perforin-deficient donor T cells in murine parent → F1 models for allogeneic bone marrow transplantation. It was found that FasL-defective B6.gld donor T cells display diminished GVHD activity but hav

APA, Harvard, Vancouver, ISO, and other styles

24

Zhou, S. "Characterising and modelling the internet topology — The rich-club phenomenon and the PFP model." BT Technology Journal 24, no. 3 (2006): 108–15. http://dx.doi.org/10.1007/s10550-006-0082-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Pogosyan, Ruben Ashotovich, Olga Vladimirovna Nesterova, Dmitry Olegovich Bokov, and Irina Alexandrovna Samylina. "QUANTITATIVE DETERMINATION OF PHENOL CARBOXYLIC ACIDS IN POMEGRANATE FRUIT PULP BY THE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH ULTRAVIOLET DETECTION." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 548. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.30589.

Full text

Abstract:

Objective: Pomegranate (Punica granatum L.) is a broadly used plant possessing a wide range of medicinal properties. In this research, we have mainly focused on the investigation of phenolic compounds of pomegranate fruit pulp (PFP).Methods: Fresh fruits of “Çəhrayı Gülöyşə,” “Kizil-anor,” and pomegranate varietal mixture were used as samples. High-performance liquid chromatography-ultraviolet (HPLC-UV) analysis of phenol carboxylic acids was performed with metal column Kromasil® C18 (4.6×250 mm, particle size 5 μm) and the acetonitrile-water-concentrated acid phosphoric system (400:600:5) und

APA, Harvard, Vancouver, ISO, and other styles

26

Pogosyan, Ruben Ashotovich, Olga Vladimirovna Nesterova, Dmitry Olegovich Bokov, and Irina Alexandrovna Samylina. "QUANTITATIVE DETERMINATION OF PHENOL CARBOXYLIC ACIDS IN POMEGRANATE FRUIT PULP BY THE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH ULTRAVIOLET DETECTION." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 548. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.30589.

Full text

Abstract:

Objective: Pomegranate (Punica granatum L.) is a broadly used plant possessing a wide range of medicinal properties. In this research, we have mainly focused on the investigation of phenolic compounds of pomegranate fruit pulp (PFP).Methods: Fresh fruits of “Çəhrayı Gülöyşə,” “Kizil-anor,” and pomegranate varietal mixture were used as samples. High-performance liquid chromatography-ultraviolet (HPLC-UV) analysis of phenol carboxylic acids was performed with metal column Kromasil® C18 (4.6×250 mm, particle size 5 μm) and the acetonitrile-water-concentrated acid phosphoric system (400:600:5) und

APA, Harvard, Vancouver, ISO, and other styles

27

Fatima, Scholes, Zhong, and Kohan. "Towards a Dynamic Model of the Kangaroo Knee for Clinical Insights into Human Knee Pathology and Treatment: Establishing a Static Biomechanical Profile." Biomimetics 4, no. 3 (2019): 52. http://dx.doi.org/10.3390/biomimetics4030052.

Full text

Abstract:

There is limited understanding of how patella realignment or patellectomy to surgically manage patellofemoral pain (PFP) affects knee biomechanics. By analysing marsupials like kangaroos that lack an ossified patella, actionable biomimetic insight for the management of end-stage PFP could be gained. This study aimed to provide the foundation of a multi-stage approach, by establishing a static biomechanical profile of the kangaroo stifle that informs the inputs and factors requiring consideration for future dynamic analyses. Volumetric CT and MRI sequences were obtained for four hindlimbs from

APA, Harvard, Vancouver, ISO, and other styles

28

Liu, Yongxin, Li Song, Peng Luo, and Hong Jin. "Theoretical study on pipe friction parameter identification in water distribution systems." Canadian Journal of Civil Engineering 46, no. 9 (2019): 789–95. http://dx.doi.org/10.1139/cjce-2018-0021.

Full text

Abstract:

In water distribution systems (WDSs), operational modeling results could be affected by accuracy of pipe friction parameters (PFPs). Under a single hydraulic condition, unique values of PFPs cannot be achieved, even with the availability of pressure and discharge values at every node. This study established a theoretical model of PFP identification in WDSs by decoupling variables. Then, equations for identifying PFPs were expressed through energy conservation equations of a tree and relationships between pressure losses and flows in pipes under different hydraulic conditions. Further, equation

APA, Harvard, Vancouver, ISO, and other styles

29

De Oliveira Silva, Danilo, Marcella F. Pazzinatto, Kay M. Crossley, Fabio M. Azevedo, and Christian J. Barton. "Novel Stepped Care Approach to Provide Education and Exercise Therapy for Patellofemoral Pain: Feasibility Study." Journal of Medical Internet Research 22, no. 7 (2020): e18584. http://dx.doi.org/10.2196/18584.

Full text

Abstract:

Background Patellofemoral pain (PFP) impairs joint- and health-related quality of life and may be associated with knee osteoarthritis. We developed a novel, 2-phase, stepped-care approach for PFP, combining (1) self-directed web-based education and exercise therapy with (2) physiotherapist-supported education and exercise therapy. Physiotherapy sessions can be provided using 2 different modalities: face-to-face and telerehabilitation. Objective This study aims to (1) determine the feasibility of our stepped-care approach, (2) explore patient-reported outcomes following self-directed web-based

APA, Harvard, Vancouver, ISO, and other styles

30

Olbrantz, Christina, Jamie Bergelin, Jill Asmus, Thomas Kernozek, Drew Rutherford, and Naghmeh Gheidi. "Effect of Posttrial Visual Feedback and Fatigue During Drop Landings on Patellofemoral Joint Stress in Healthy Female Adults." Journal of Applied Biomechanics 34, no. 1 (2018): 82–87. http://dx.doi.org/10.1123/jab.2017-0074.

Full text

Abstract:

Patellofemoral pain (PFP) is common in females. Patellofemoral joint stress (PFJS) may be important in the development of PFP. Ground reaction force (GRF) during landing activities may impact PFJS. Our purpose was to determine how healthy females alter their landing mechanics using visual posttrial feedback on their GRF and assess how PFJS changes. Seventeen participants performed a series of drop landings during 3 conditions: baseline, feedback, and postfatigue feedback. The fatigue protocol used repetitive jump squats. Quadriceps force was estimated through inverse-dynamics-based static opti

APA, Harvard, Vancouver, ISO, and other styles

31

Amin, Muhammad Umair, Sajid Ali, Imran Tariq, et al. "Ultrasound-Responsive Smart Drug Delivery System of Lipid Coated Mesoporous Silica Nanoparticles." Pharmaceutics 13, no. 9 (2021): 1396. http://dx.doi.org/10.3390/pharmaceutics13091396.

Full text

Abstract:

The immediate release of chemotherapeutics at the target site, along with no premature release in circulation is always challenging. The purpose of this study was to develop a stimuli responsive drug delivery system, composed of lipid supported mesoporous silica nanoparticles (MSNPs) for triggered drug release at the target site and simultaneously avoiding the premature release. MSNPs with a higher drug loading capacity and very slow release were designed so as to enhance release by FDA approved US-irradiation. Doxorubicin, as a model drug, and perfluoropentane (PFP) as a US responsive materia

APA, Harvard, Vancouver, ISO, and other styles

32

Gebauer, Florian, Daniel Wicklein, Katrin Stübke, et al. "Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp−−/rag2−−mice." Gut 62, no. 5 (2012): 741–50. http://dx.doi.org/10.1136/gutjnl-2011-300629.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Seyyedsalehi, Seyyede Fatemeh, Mahdieh Soleymani, Hamid R. Rabiee, and Mohammad R. K. Mofrad. "PFP-WGAN: Protein function prediction by discovering Gene Ontology term correlations with generative adversarial networks." PLOS ONE 16, no. 2 (2021): e0244430. http://dx.doi.org/10.1371/journal.pone.0244430.

Full text

Abstract:

Understanding the functionality of proteins has emerged as a critical problem in recent years due to significant roles of these macro-molecules in biological mechanisms. However, in-laboratory techniques for protein function prediction are not as efficient as methods developed and processed for protein sequencing. While more than 70 million protein sequences are available today, only the functionality of around one percent of them are known. These facts have encouraged researchers to develop computational methods to infer protein functionalities from their sequences. Gene Ontology is the most

APA, Harvard, Vancouver, ISO, and other styles

34

Sandeep, D. S., R. Narayana Charyulu, and Prashant Nayak. "COMPARATIVE STUDY OF SUPERDISINTEGRANTS USING ANTIEMETIC DRUG AS A MODEL." Journal of Health and Allied Sciences NU 05, no. 01 (2015): 040–44. http://dx.doi.org/10.1055/s-0040-1703861.

Full text

Abstract:

AbstractIn the present investigation comparison of three different superdisintegrants was carried out by formulating orally disintegrating tablets. Promethazine HCl was used as model drug which is an antiemetic drug. Sodium starch glycolate, croscarmellose and crospovidone were selected as superdisintegrants and each one was used in three different concentrations (2%, 3.5% and 5%). The drug-polymer compatibility was ruled out by FTIR studies. A total of nine formulations (PF1-PF9) were made by direct compression. All prepared formulations were evaluated for weight variation, hardness, friabili

APA, Harvard, Vancouver, ISO, and other styles

35

Mahajan, Arvind R., and Sunil R. Mirgane. "Excess Molar Volumes and Viscosities for the Binary Mixtures of n-Octane, n-Decane, n-Dodecane, and n-Tetradecane with Octan-2-ol at 298.15 K." Journal of Thermodynamics 2013 (June 25, 2013): 1–11. http://dx.doi.org/10.1155/2013/571918.

Full text

Abstract:

Experimental values of densities (ρ) and viscosities (η) in the binary mixtures of n-octane, n-decane, n-dodecane, and n-tetradecane with octan-2-ol are presented over the whole range of mixture composition at T=298.15 K. From these data, excess molar volume (VmE), deviations in viscosity (Δη), and excess Gibbs free energy of activation ΔG∗E have been calculated. These results were fitted to Redlich-Kister polynomial equations to estimate the binary coefficients and standard errors. Jouyban-Acree model is used to correlate the experimental values of density and viscosity at T=298.15 K. The val

APA, Harvard, Vancouver, ISO, and other styles

36

Colace, Thomas Vincent, and Scott L. Diamond. "Direct Observation of Von Willebrand Factor Elongation and Fiber Formation On Collagen During Acute Whole Blood Exposure to Pathological Flow." Blood 120, no. 21 (2012): 1070. http://dx.doi.org/10.1182/blood.v120.21.1070.1070.

Full text

Abstract:

Abstract Abstract 1070 Under conditions of pathological shear rate, von Willebrand Factor (vWF) undergoes conformational changes and self aggregation. We sought to visualize this phenomenon using a novel microfluidic model of stenosis and understand its role in thrombus formation in elevated shear rate environments. In severe stenosis, vWF experiences millisecond exposures to pathological wall shear rates (gw). Distinct from shear experiments that last many seconds, we deployed microfluidic devices for single-pass perfusion of whole blood or platelet free plasma (PFP) over fibrillar type 1 col

APA, Harvard, Vancouver, ISO, and other styles

37

Makhaeva, G. F., E. V. Rudakova, and R. J. Richardson. "Investigation of the Esterase Status as a Complex Biomarker of Exposure to Organophosphorus Compounds." Biomedical Chemistry: Research and Methods 1, no. 3 (2018): e00028. http://dx.doi.org/10.18097/bmcrm00028.

Full text

Abstract:

Development of biomarkers of human exposures to organophosphorus compounds OPCs and their quantification is a vital component of a system of prediction and early diagnostics of OPC-induced diseases. Our study was focused on investigation of esterase status as a complex biomarker of exposure to OPCs and an aid in accurate diagnosis. We suggest that this complex biomarker should be more effective and informative than standard assays of plasma butyrylcholinesterase (BChE), erythrocyte acetylcholinesterase (RBC AChE), and lymphocyte neuropathy target esterase (NTE). It will help: 1) to assess an e

APA, Harvard, Vancouver, ISO, and other styles

38

Maeda, Yoshinobu, Robert B. Levy, Pavan Reddy, Chen Liu, Takanori Teshima, and James L. M. Ferrara. "Perforin and Fas Ligand Are Required for the Regulation of Alloreactive CD8+ T Cells." Blood 104, no. 11 (2004): 3052. http://dx.doi.org/10.1182/blood.v104.11.3052.3052.

Full text

Abstract:

Abstract We evaluated the role of Fas ligand and perforin, the major T cell-mediated cytotoxic pathways that regulate T cell homeostasis, in a CD8+ T cell mediated model of graft-versus-host disease (GVHD) where donor and recipients differ at a single MHC class I antigen (B6 → bm1). Lethally irradiated (11Gy) bm1 mice were transplanted with T cell depleted BM and CD8+ T cells from either wild type (wt) or cytotoxic double deficient (cdd, deficient in both pathways) B6 donors. We hypothesized that cdd CD8+ T cells would be unable to mediate significant GVHD. Contrary to our hypothesis, recipien

APA, Harvard, Vancouver, ISO, and other styles

39

He, Ping, Endong Zhang, Ruilian Qi, Fengting Lv, Libing Liu, and Shu Wang. "Application of Cationic Conjugated Polymer–Outer Membrane Vesicle Complexes in Inhibiting Red Blood Cell Aggregation." Organic Materials 01, no. 01 (2019): 038–42. http://dx.doi.org/10.1055/s-0039-1700849.

Full text

Abstract:

Cationic conjugated polymers (CCPs) have been attracting a lot of attention in biomedical applications because of their good photoelectric properties and good cell viability. However, positively charged components may reduce the electrostatic repulsion among red blood cells (RBCs) and induce RBC aggregation, which may lead to thrombus. Herein, in this work, we prepared the complexes of CCPs and outer membrane vesicles (OMVs) to inhibit RBC aggregation induced by CCPs and improve the biocompatibility of CCPs. A poly(fluorene-co-phenylene) derivative (PFP), a poly(p-phenylenevinylene) derivative

APA, Harvard, Vancouver, ISO, and other styles

40

Patruno, Rosa, Ilaria Marech, Nicola Zizzo, et al. "C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies." BioMed Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/730246.

Full text

Abstract:

Canine cutaneous mast cell tumour (CMCT) is a c-Kit driven tumour sharing similar c-Kit aberrations found in human gastrointestinal stromal tumour. CMCT is classified into three forms: well- (G1), intermediately (G2) (more benign diseases), and poorly (G3) differentiated (malignant) forms. We assess a correlation between c-Kit status, grading, and angiogenesis in CMCTs to explore their potential significance in humans. C-Kit receptor (c-KitR) expression, microvascular density (MVD), and mast cell granulated and degranulated status density (MCGD and MCDD, resp.) were analyzed in 97 CMCTs, by me

APA, Harvard, Vancouver, ISO, and other styles

41

Favaretto, Fábio, and Carlos Frederico Bremer. "Sistematização para a implantação integrada de sistemas de planejamento fino da produção." Gestão & Produção 4, no. 1 (1997): 108–16. http://dx.doi.org/10.1590/s0104-530x1997000100006.

Full text

Abstract:

As mudanças ocorridas no cenário mundial têm levado as empresas de manufatura a buscar um aumento da sua flexibilidade. O Planejamento e Controle da Produção (PCP) é a função da empresa que é mais sensível às mudanças necessárias em direção a um aumento da flexibilidade. Os sistemas de Planejamento Fino da Produção (PFP) são ferramentas que surgiram com o objetivo de auxiliar a função de PCP nessa busca pela flexibilidade. Os sistemas de PFP fazem a ligação entre a dinâmica do chão-de-fábrica e o ambiente de planejamento, e a sua implantação é um fator crítico para que as necessidades e expect

APA, Harvard, Vancouver, ISO, and other styles

42

Šurda, Peter, Ľubomír Lichner, Jozef Kollár, Anton Zvala, and Dušan Igaz. "Evaluation of soil properties in variously aged Scots pine plantations established on sandy soil." Journal of Hydrology and Hydromechanics 69, no. 3 (2021): 347–55. http://dx.doi.org/10.2478/johh-2021-0012.

Full text

Abstract:

Abstract Pines are widely planted for sand dune stabilization and their cultivation results in the changes in physical, chemical, hydro-physical and water repellency properties. Soil properties were evaluated at three Scots pine plantations (PF1, PF2 and PF3) close to Studienka village, Borská nížina lowland (southwestern Slovakia) during hot and dry summer period. The PF1 site is a newly established plantation, the PF2 site is about 30 years old plantation, and the PF3 site is about 100 years old plantation. Here, we estimated the differences in pH, soil organic carbon content, Cox, particle

APA, Harvard, Vancouver, ISO, and other styles

43

Iloukhani, H., and M. Almasi. "Densities and Excess Molar Volumes of Binary and Ternary Mixtures Containing Acetonitrile + Acetophenone + 1,2-Pentanediol: Experimental Data, Correlation and Prediction by PFP Theory and ERAS Model." Journal of Solution Chemistry 40, no. 2 (2011): 284–98. http://dx.doi.org/10.1007/s10953-010-9637-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Tesfay, Teklay, Abadi Berhane, and Mebrahtu Gebremariam. "Optimizing Irrigation Water and Nitrogen Fertilizer Levels for Tomato Production." Open Agriculture Journal 13, no. 1 (2019): 198–206. http://dx.doi.org/10.2174/1874331501913010198.

Full text

Abstract:

Background: Though nitrogen and water are key factors for tomato production, their optimum integration is not well identified in the study area. Therefore, optimizing irrigation level and nitrogen fertilizer rates are crucial to boost tomato yield as well as for better nutrient and Water Use Efficiency (WUE). Objective: The objective of the present study was to determine the optimum irrigation water and nitrogen fertilizer levels for higher tomato yield, improved water and nutrient use efficiencies. Methods: Split plot design was implemented with three irrigation levels expressed as a percenta

APA, Harvard, Vancouver, ISO, and other styles

45

Tanqueiro, Sara R., Francisco M. Mouro, Catarina B. Ferreira, et al. "Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice." Journal of Psychopharmacology 35, no. 6 (2021): 730–43. http://dx.doi.org/10.1177/02698811211008560.

Full text

Abstract:

Background: Cognitive deficits profoundly impact on the quality of life of patients with schizophrenia. Alterations in brain derived neurotrophic factor (BDNF) signalling, which regulates synaptic function through the activation of full-length tropomyosin-related kinase B receptors (TrkB-FL), are implicated in the aetiology of schizophrenia, as is N-methyl-D-aspartate receptor (NMDA-R) hypofunction. However, whether NMDA-R hypofunction contributes to the disrupted BDNF signalling seen in patients remains unknown. Aims: The purpose of this study was to characterise BDNF signalling and function

APA, Harvard, Vancouver, ISO, and other styles

46

Huang, Liusheng, Janus Anders Juul Haagensen, Davide Verotta, et al. "Determination of Tobramycin in M9 Medium by LC-MS/MS: Signal Enhancement by Trichloroacetic Acid." Journal of Analytical Methods in Chemistry 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/7965124.

Full text

Abstract:

It is well known that ion-pairing reagents cause ion suppression in LC-MS/MS methods. Here, we report that trichloroacetic acid increases the MS signal of tobramycin. To support studies of an in vitro pharmacokinetic/pharmacodynamic simulator for bacterial biofilms, an LC-MS/MS method for determination of tobramycin in M9 media was developed. Aliquots of 25 μL M9 media samples were mixed with the internal standard (IS) tobramycin-d5 (5 µg/mL, 25 µL) and 200 µL 2.5% trichloroacetic acid. The mixture (5 µL) was directly injected onto a PFP column (2.0 × 50 mm, 3 µm) eluted with water containing

APA, Harvard, Vancouver, ISO, and other styles

47

Meledeo, Michael A., James E. Campbell, Armando C. Rodriguez, Melanie V. Valenciana, and Andrew P. Cap. "Activated Protein C Levels Found In Trauma Patients Are Insufficient To Inactivate Platelet Factor Va and Produce Coagulopathy In An In Vitro Model." Blood 122, no. 21 (2013): 4767. http://dx.doi.org/10.1182/blood.v122.21.4767.4767.

Full text

Abstract:

Background A subset of severe trauma victims suffering from uncontrolled hemorrhage present to the emergency room with an acute coagulopathy of trauma (ACoT). This condition occurs within the first 30 min following injury, is not the result of resuscitation-associated dilutional effects, and is defined by an INR > 1.2. The mechanisms behind this coagulopathy have not been completely identified, but recent studies posit that the exuberant activation of protein C is a key contributor to ACoT. Protein C is activated through the interaction of thrombin and thrombomodulin on the endothelial surf

APA, Harvard, Vancouver, ISO, and other styles

48

Hameed, Fazli, Junzeng Xu, Shah Rahim, Qi Wei, Anis Rehman Khalil, and Qi Liao. "Optimizing Nitrogen Options for Improving Nitrogen Use Efficiency of Rice under Different Water Regimes." Agronomy 9, no. 1 (2019): 39. http://dx.doi.org/10.3390/agronomy9010039.

Full text

Abstract:

Major challenge in rice production is to achieve the goal of enhancing both food production and fertilizer use efficiency. Rice growth simulation model, ORYZA (v3) was used in the present study to evaluate the model under continuous flooded (CF) and alternate wetting and drying (AWD) regimes with different fertilizer nitrogen (N) rates with different N splits using a historical data of past 45 years. The model satisfactorily simulated crop biomass and nitrogen uptake at both irrigation regimes and fertilizers N rates and splits. The yield differences among the years were large due to climate c

APA, Harvard, Vancouver, ISO, and other styles

49

Alekseenko, O. P. P., D. I. I. Potapenko, S. G. G. Cherny, D. V. V. Esipov, D. S. S. Kuranakov, and V. N. N. Lapin. "3D Modeling of Fracture Initiation From Perforated Noncemented Wellbore." SPE Journal 18, no. 03 (2013): 589–600. http://dx.doi.org/10.2118/151585-pa.

Full text

Abstract:

Summary A 3D numerical model of fracture initiation from a perforated wellbore in linear elastic rock is developed, which allows one to determine the fracture-initiation pressure (FIP) and the location and direction of an initial rupture. The model assumes that the fracture initiates at the point at which the local maximal tensile stress exceeds the rock tensile strength. The 3D boundary-element method (BEM) is used for stress analysis. The model aims to predict the location of initial fractures and the difference in FIP between different perforation intervals in arbitrarily oriented noncement

APA, Harvard, Vancouver, ISO, and other styles

50

Rubio-Camacho, Marta, Yolanda Alacid, Ricardo Mallavia, María José Martínez-Tomé, and C. Reyes Mateo. "Polyfluorene-Based Multicolor Fluorescent Nanoparticles Activated by Temperature for Bioimaging and Drug Delivery." Nanomaterials 9, no. 10 (2019): 1485. http://dx.doi.org/10.3390/nano9101485.

Full text

Abstract:

Multifunctional nanoparticles have been attracting growing attention in recent years because of their capability to integrate materials with different features in one entity, which leads them to be considered as the next generation of nanomedicine. In this work, we have taken advantage of the interesting properties of conjugated polyelectrolytes to develop multicolor fluorescent nanoparticles with integrating imaging and therapeutic functionalities. With this end, thermosensitive liposomes were coated with three recently synthesized polyfluorenes: copoly-((9,9-bis(6′-N,N,N-trimethylammonium)he

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!