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1

Riddoch, B. "Selection component analysis of the PGI polymorphism in Sphaeroma rugicauda." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378440.

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2

Massot, Véronique. "Audit légal et technologies organisationnelles : l'exemple de l'environnement PGI en PME." Thesis, Montpellier 2, 2011. http://www.theses.fr/2011MON20243/document.

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L'objet de la thèse est d'analyser à travers l'étude des représentations et du comportement décisionnel du commissaire aux comptes, le processus d'audit légal dans un contexte de PME dont le système d'information est basé sur un PGI. Par conséquent, il s'agit de déterminer si la présence d'un système informatique intégré au sein de la PME contrôlée, est de nature à faire évoluer le processus d'audit légal. Dans le cadre d'une démarche interprétative et qualitative, des investigations ont été menées auprès de commissaires aux comptes, auditant en univers PGI/PME. Elles ont permis d'énoncer deux résultats majeurs. Le premier révèle que les progiciels de gestion intégrés sont créateurs de confiance pour certains répondants, mais suscitent également de la défiance pour d'autres. Toutefois, c'est la position critique qui est dominante. Le second enseignement de cette recherche souligne qu'il existe une évolution variable dans la pratique des auditeurs, ce qui met partiellement en échec la théorie de l'adaptabilité décisionnelle de l'individu. Plus généralement, les observations tendent à montrer que la technologie PGI ne remet pas en cause la finalité et les fondements de la démarche du certificateur
The aim of this thesis is to analyse - through the study of the representations and decision-making behaviour of the legal auditor - the legal audit process in an SME-context where the information system is based on an ERP. Therefore, we intend to determine whether the presence of an integrated information system within the audited SME is likely to alter the legal audit process. In the framework of an interpretative and qualitative approach, investigations were carried out among legal auditors working in an SME/ERP environment. These surveys have allowed us to formulate two major results. The first result reveals that ERPs are trustworthy systems to some respondents, but they also arouse mistrust in others. However, on the whole, the sentiment of mistrust prevails. The second result of this research indicates that varied and unsettled changes exist in each auditors'work methods, which partly challenges the theory of individual decision-making adaptability. More generally speaking, observations tend to show that ERP technology doesn't call into question the purpose and the fondations of the auditor's approach
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3

McDonald, D. P. "Genetics, physiology and biochemistry of the PGI polymorphism in Asellus aquaticus (L.)." Thesis, University of Essex, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328752.

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4

Eugenio, Luiz Marcelo. "Expressão, purificação,caracterização e modelagem molecular da enzima phosphoglucose isomerase de Trypanosoma Brucei." Universidade de São Paulo, 2001. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-06052008-092309/.

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A tripanossomose africana, ou doença do sono, como é popularmente conhecida, atingiu 25 mil pessoas só em 1995. Estima-se que a doença seja responsável pela morte de 10.000 pessoas a cada ano, segundo os dados da Organização Mundial da Saúde. Sua distribuição é exclusivamente africana, devido ao fato de sua transmissão depender da Tsé-Tsé, mosca do gênero Glossina que encontra lá condições favoráveis para sua proliferação. Atualmente os medicamentos existentes não são eficientes e devem ser ministrados em doses altas, provocando graves efeitos colaterais. O parasita Tripanosoma brucei, na forma encontrada no sangue dos mamíferos (tripomastigota), é o responsável pela doença e, assim como toda a família Trypanosomatidea, é altamente dependente de glicose. Esses parasitas consomem a quantidade de glicose equivalente à sua massa em aproximadamente sete horas. A via glicolítica torna-se, portanto, chave para o desenvolvimento de inibidores que possam ser utilizados no combate a estes parasitas. Nesse sentido, temos realizado estudos com a enzima glicose-6-fosfato isomerase (glucose-6-fosfato isomerase; Phosphoglucose Isomerase PGI; EC 5.3.1.9), responsável pela isomerização reversível da D-glicose-6-fosfato e D-frutose-6-fosfato e participa na glicólise como a segunda enzima da via. Os trabalhos realizados até aqui culminaram na sua expressão em forma recombinante, purificação através de coluna de afinidade, e caracterizações enzimáticas. Sua atividade específica foi determinada através de métodos já estabelecidos encontrados na literatura. O IC50 da enzima frente a quatro inibidores da reação foi determinado. O trabalho finaliza com a construção de um modelo estrutural da enzima determinado através de métodos de modelagem molecular por homologia.
The African trypanosomiasis, or sleeping sickness as is popularly known, affected 25 thousand people only in 1995. It is estimated that the disease is responsible for 10 thousand deaths per year, according to data provided from the World Health Organization (WHO). The distribution of the disease is exclusively African due to the transmission being dependent on the tsé-tsé vector. A fly, belonging to the Glossinia genus, finds in the African continent favorable conditions for its proliferation. Presently the existing drugs are not efficient and have to be applied in high dosage, resulting in severe side effects. The bloodstream form (tripomastigote) of the parasite Trypanosoma brucei is responsible for the disease and such as the whole Trypanosomatidae family is dependent on glucose. Those parasites consume a quantity of glucose equivalent to its mass in approximately seven hours. This characteristic results in the glycolitic pathway been a key target for drug development against those parasites. In this direction we are developing research with the enzyme glucose-6-phosphate isomerase (Phosphoglucose lsomerase PGI; EC 5.3.1.9) responsible for the reversible isomnerisation of D-glucose6-phosphate and D-fuctcose-6-phosphate. PGI participates as the second enzyme in the glycolytic pathway. The work developed so far resulted in the expression of the recombinant form of the parasite PGI, its affinity purification and enzimatic characterization. The specific activity was determined with established methods. The IC50 of four inhibitors was determined and a structural model of T brucei PGI was built by molecular modeling techniques.
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5

Zado, Victoria Yousip. "The General Information Programme (PGI) and developing countries : a case study of Iraq." Thesis, Loughborough University, 1990. https://dspace.lboro.ac.uk/2134/7131.

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6

Yeni, Filiz. "Determination Of Polymorphism Of Pgm, Hk, Pgi, And G6pd In Different Developmental Stages Of Honey Bee (apis Mellifera L.) And Its Relation With Pgm Activity And Glycogen Content." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/2/12611930/index.pdf.

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In this study, three subspecies of Apis mellifera L. (A. m. caucasica, A. m. carnica, and A. m. syriaca) from different climatic regions were evaluated electrophoretically at ontogenetic level by means of four enzymes, namely Phosphoglucomutase (PGM), Hexokinase (HK), Phosphoglucose isomerase (PGI) and Glukose-6-phosphate dehydrogenase (G6PD). It is determined that only Pgm and Hk loci were polymorphic. Allele and genotype frequencies at Pgm locus changes seasonally whereas Hk locus does not exhibit seasonal variation. Within the scope of this study we investigated at which developmental stage shifting to heterozygotes prior to winter occurs. It is found that there is a seasonal fluctuation throughout the year in Pgm genotype frequencies at each developmental stage studied and correlated with enzyme activity and glycogen content. As the studied enzymes have crucial v roles in insect energy metabolism, results of this study provided further information about the relationship between carbohydrate metabolism and enzyme polymorphism of honey bees.
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7

Westermann, Katharina [Verfasser]. "Pferdegestützte Interventionen (PGI) zur Gesundheitsförderung des Menschen : Einsatzvoraussetzungen, Anforderungen, Belastungsmomente, Ausbildung und Leistungsprüfung des Pferdes / Katharina Westermann." Berlin : Freie Universität Berlin, 2013. http://d-nb.info/1044891947/34.

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8

Salgado, Rojas Mario Rolando. "Rediseño del Proceso de Atención a los Técnicos y Soporte a la PGI en Telefónica CTC Chile." Tesis, Universidad de Chile, 2009. http://repositorio.uchile.cl/handle/2250/102103.

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El proyecto consiste en el rediseño del proceso de instalación de ADSL (Banda Ancha), con énfasis en los procesos de gestión de producción, en la entrega del servicio y de las actividades de apoyo que realiza la Plataforma de Gestión de las Instalaciones (PGI) para asistir al técnico en el momento de presentarse un problema o falla en la instalación. Dichos problemas pueden ir desde la inexistencia de un par de cobre en el armario para conectar al nuevo cliente hasta un cambio en el producto solicitado por parte del cliente al momento de la instalación. Para solucionar estas situaciones, el técnico debe contactarse vía telefónica con la PGI, donde una operadora realizará las gestiones que se requieran para resolver dicho problema en la instalación. Como respuesta a esta problemática, se diseñó una solución de auto-atención utilizando un dispositivo inalámbrico, el cual permite conectividad con los sistemas de Telefónica, permitiendo autonomía y resolución de las distintas situaciones que se presentan en la casa del cliente. Para el modelamiento, tanto de la situación actual como la mejorada, se utiliza la metodología desarrollada por el Dr Oscar Barros para el rediseño de los procesos de negocios con soporte de Tecnologías de la Información. Además se utiliza el FrameWork Etom, el cual ha sido diseñado por un conglomerado de las empresas de Telecomunicaciones más importantes a nivel mundial. En él se plasma las actividades y procesos que debiera tener y realizar una empresa de telecomunicaciones “modelo” en la industria. Como resultado de éste proyecto se obtuvo el ordenamiento de los procesos actuales de la PGI, resolución por tipología, generación de data necesaria para realizar análisis sobre dichas ocurrencias y mejor percepción por parte de los clientes al momento de instalar. Se obtuvieron reducciones de hasta un 50% en llamadas no atendidas y segundos llamados, lo cual se traduce en ahorros de $6 Millones por este concepto y se generan facturaciones tempranas por montos de $9.5 Millones mensuales sólo por ADSL.
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9

Poba-Nzaou, Placide. "Processus d'adoption et réduction du risque d'implantation des PGI dans les PME : une étude de cas multiples." Thèse, Université du Québec à Trois-Rivières, 2008. http://depot-e.uqtr.ca/1877/1/030105355.pdf.

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10

Falson-Boutherin, Odile. "Effet de la nicotine sur les cellules endothéliales vasculaires humaines en culture prolifération cellulaire et production de PGI /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37604936t.

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11

Jabraoui, Siham. "L' intégration organisationnelle des PGI et la démarche stratégique des entreprises industrielles: étude des configurations et des dynamiques." Versailles-St Quentin en Yvelines, 2011. http://www.theses.fr/2011VERS004S.

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Ce que l’on appelle l’« implémentation » des progiciels de gestion intégrés (PGI), conduit généralement à une refonte du système d’information de gestion, et à une remise à plat des procédures de gestion en place, lesquelles peuvent être par la suite réorganisées suivant les orientations stratégiques ciblées par l’entreprise. Les principaux problèmes commencent lorsqu’il s’agit d’intégrer les fonctionnalités spécifiques à chaque entreprise dans le PGI. Entre la standardisation des processus de gestion et la personnalisation du PGI, les entreprises semblent être souvent en quête d’un équilibre qui reflète la cohérence de leurs choix et de leurs décisions avec leurs orientations stratégiques. C’est sur ce thème de la recherche d’équilibre que notre thèse se positionne. Elle vise dans ce cadre à explorer les différents choix stratégiques effectués par les entreprises pour intégrer un PGI. C’est sur la base de ces choix que nous avons tenté de décrypter les différentes modalités adoptées pour intégrer ces progiciels, à partir d’une enquête qualitative par entretiens semi-directifs auprès de 16 entreprises industrielles. Il en est sorti trois configurations de base construites au niveau local des entités concernées par l’intégration, et une quatrième configuration dite "mixte" qualifiant la synergie de l’ensemble des configurations adoptées à l’échelle globale de l’entreprise. L’analyse de l’évolution de ces modalités dans le temps est une question qui s’est révélée indispensable, dans la mesure où elle permet de prendre en compte le caractère ouvert et dynamique des processus d’intégration organisationnelle des PGI
What is called « implementation » of Enterprise Resource Planning (ERP) usually leads to a rebuilding of management information systems, and to a revisit of management procedures that can be thereafter reorganized according to the company’s strategic orientations. The main problems start when one wants to integrate specific functionalities of a particular company into the ERP. Between the standardization of management procedures and the personalization of ERP, companies often seem to look for a balance that reflects the coherence of their choices and decisions according to their strategic orientations. It’s this topic of balance which constitutes the heart of this dissertation. This research aims to explore the various strategic choices done by companies to integrate ERP. It’s on the basis of these choices that we have tried to decrypt the different modalities adopted to integrate these softwares. We have found three basic configurations built on local levels of the entities concerned by the integration, and a fourth mixed configuration qualifying the synergy of the overall configurations adopted to the wider level of the company. The analysis of the longitudinal evolution of these modalities is a question that appeared to be directly related to the basic problem, because it allows to take into consideration the opened and dynamic behavior of integration processes
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12

Moita, Mário Francisco Quintas Leitão Dias. "Notoriedade dos produtos tradicionais de origem animal (DOP e IGP) do Alentejo." Master's thesis, Universidade de Évora, 2009. http://hdl.handle.net/10174/18543.

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O presente trabalho visa conhecer o nível de notoriedade dos produtos tradicionais de origem animal (DOP e IGP) do Alentejo no mercado consumidor. Este objectivo foi alcançado através da realização de revisão bibliográfica com recurso às fontes secundárias disponíveis e de fontes primárias, nomeadamente de um questionário de avaliação da notoriedade dos produtos tradicionais (DOP e IGP) de origem animal do Alentejo expressamente desenvolvido para o efeito. A informação obtida permitiu caracterizar a oferta dos produtos tradicionais de origem animal do Alentejo, em termos quantitativos, qualitativos e diversidade, enquadrar teoricamente o tema da notoriedade no contexto do comportamento do consumidor e do marketing agro-alimentar e identificar os procedimentos metodológicos a serem utilizados e delineamento do trabalho de investigação. A análise dos dados recolhidos por inquérito, tratados com recurso a software e técnicas estatísticas descritivas, permitiram retirar conclusões relevantes, tais como a baixa notoriedade dos produtos DOP e IGP, o produto com mais notoriedade, Top-of-Mind, a Carnalentejana, entre outros. Foram identificados tanto nas fontes primárias como nas secundárias aspectos em comum: uma baixíssima notoriedade dos produtos certificados e uma preocupação e necessidade em haver mais acções de divulgação destes produtos. Dos 33 produtos certificados de origem animal do Alentejo, apuraram-se que apenas 26 se encontram a ser comercializados e em que muitos casos os agrupamentos remetem para os produtores a responsabilidade da promoção dos produtos. Foram ainda identificados tópicos para futuras pesquisas e para acções de marketing tendentes a melhorar a notoriedade dos produtos tradicionais de origem animal do Alentejo no mercado. ABSTRACT; The present work aims to know the level of renown of the traditional products of animal origin (DOP and IGP) of the Alentejo in the consumer market. This objective was reached through the realization of bibliographical revision with resource to the available secondary fountains and of primary fountains, namely of a questionnaire of evaluation of the renown of the traditional products (DOP and IGP) of animal origin of the Alentejo definitely developed for the effect. The obtained information allowed to characterize the offer of the traditional products of animal origin of the Alentejo, in quantitative, qualitative terms and diversity, to fit theoretically the subject of the renown in the context of the behavior of the consumer and of the food-rough marketing and to identify the methodological proceedings being used and delineation of the work of investigation. The analysis of the data gathered by inquiry, treated with resource the software and descriptive statistical techniques, allowed there withdrew relevant conclusions, such as the low renown of the products DOP and IGP, the product with more renown, Top-of-Mind, was the Carnalentejana, between others. Aspects were identified so much in the primary fountains how in secondary in common: a low renown of the certified products and a preoccupation and necessity in having more actions of spread/promotion of these products. Of 33 products made sure of animal origin of the Alentejo, they perfected that you punish 26 they are being marketed and in what many cases the groupings send for the producers the responsibility of the promotion of the products. Topics were still identified for future inquiries and for tending actions of marketing to improve the renown of the traditional products of animal origin of the Alentejo in the market.
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13

Wilson, Natasha. "Consumer attitudes towards regional foods : a case study of protected designation of origin (PDO) and protected geographical indication (PGI) products." Thesis, Imperial College London, 2002. http://hdl.handle.net/10044/1/8513.

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14

Hartman, Ewa. "'Giving effect to policy' : a legal and empirical investigation of the implementation of European food quality schemes in Poland (PDO, PGI, TSG)." Thesis, Bournemouth University, 2012. http://eprints.bournemouth.ac.uk/20979/.

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Legal scholarship regarding the implementation of European Union law recognises the gap between policy, enacted law and its application. Writers typically focus on the role of the European Court of Justice, the role of the European Commission, as well as the obligations of Member States under European law stemming from the Treaties (and in a broader context, from the association with the European Union). Political science literature offers a different explanation of the same gap between policy and implementation, highlighting the presence of extra-legal factors obstructing the occurrence of desired social changes. The literature has identified a number of variables which determine implementation outcomes, and suggested contextual conditions which may be conducive to ‘giving effect to policy’. This thesis explores tensions arising from legal concepts of direct applicability and compliance, and political science concepts of implementation and practical effectiveness with reference to voluntary food quality schemes in Poland, in particular the laws of Protected Designations of Origin (PDO), Protected Geographical Indications (PGI) and Traditional Specialties Guaranteed (TSG). The core of the research is an empirical study, using semi-structured interviews with actors at all levels of implementation of these laws in Poland: at the ministerial, regional and local level, including officials and producer consortia. An interview protocol derived from the theories of implementation in political science and law investigates the implementation chain in its entirety, from policy formation to the legislative act, and finishing with the ‘recipients’ themselves, the targets of legal intervention. The results show that a lack of effectiveness does not mean non-compliance (in law) of an EU Member State. Member States might have implemented the Community legislation fully by creating a regulatory environment indispensable to its success. Yet, for implementation to be effective, enforcement agents must themselves be committed to the behaviour required by the law, circumstances external to the implementing agency should not impose critical constraints, and the recipients must be persuaded of the benefits of participating in voluntary schemes. These findings appear to support the political science theory of perfect implementation and effectiveness of law, and highlight gaps in enforcement mechanisms available to the Union Institutions. For example, the European Court of Justice acts against non-compliance on the Commission’s motion, whereas the Commission often relies on claims lodged by Member States or other entitled actors, rather than on its own investigation. The findings also confirm that political science models designed for international or national law remain valid for European Union law and can be applied in its specific context.
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Carpes, Pâmela Billig Mello. "Participação da via NTS-PGI-LC-hipocampo (núcleo do trato solitário- núcleo paragigantocelular-Locus coeruleus-hipocampo) na consolidação da memória de reconhecimento de objetos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/24681.

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Existem crescentes evidências sobre a contribuição da liberação de noradrenalina (NA) central na consolidação das memórias. Teoricamente, o Núcleo do Trato Solitário (NTS) recebe informações e diversos estímulos periféricos, que são então projetados ao Núcleo Paragigantocelular (PGi). Este, por sua vez, utiliza neurotransmissores, predominantemente excitatórios, para influenciar a ativação do Locus Coeruleus (LC). Então, o LC envia projeções noradrenérgicas ao hipocampo e à amígdala, influenciando os processos mnemônicos. Aqui nós demonstramos que a inibição pelo muscimol do NTS, PGi ou LC até 3 horas após o treino na tarefa de reconhecimento de objetos (RO) impede a consolidação da memória medida 24 h após o treino. Adicionalmente, a infusão de timolol, um antagonista de receptores β-adrenérgicos, na região CA1 do hipocampo também impede a consolidação deste tipo de memória. A infusão de NA na região CA1 do hipocampo não altera a retenção da memória, mas, reverte o prejuízo causado pela inibição do NTS, PGi ou LC. A infusão de NMDA no LC após a inibição do NTS ou PGi também reverte essa amnésia. Concomitantemente, verificamos que a inibição NTS, PGi ou LC bloqueia o aumento da expressão do fator neurotrófico derivado do cérebro (BDNF, do inglês brain-derived neurotrophic factor) que ocorre 120 min após o treino na tarefa de reconhecimento de objetos na região CA1 do hipocampo. Também a infusão de NA na região CA1 do hipocampo após a inibição do NTS, PGi ou LC ou de NMDA no LC após a inibição do NTS ou PGi promovem novamente o aumento do BDNF120 min após o treino no RO. Com isso conclui-se que a ativação da via NTS-PGi-LC-Hipocampo é necessária para que ocorra consolidação da memória de RO, na qual desempenha um papel o BDNF hipocampal.
There is evidence of the contribution of brain noradrenaline release (NA) to memory consolidation. The Nucleus of the Solitary Tract (NTS) receives information originated by peripheral stimuli and projects to the Paragigantocellularis Nucleus (PGi), which influences the Locus Coeruleus (LC) through excitatory neurotransmitters. The LC sends noradrenergic projections to the hippocampus and amygdala, influencing the memory processes. Here we show that inhibition by muscimol of NTS, PGi or LC up to 3 h after object recognition training impairs the consolidation of the memory measured 24 h later. Additionally, the infusion of timolol in the CA1 region of hippocampus also inhibits consolidation of this type of memory. The infusion of NA into the CA1 region of hippocampus does not alter memory consolidation of this task, but reverts the deleterious effect of NTS, PGi or LC inhibition. The infusion of NMDA in LC after inhibition of NTS or PGi also reverts the amnesia. Concomitantly, the inhibition of NTS, PGi or LC blocks the increase of brain-derived neurotrophic factor (BDNF) expression in CA1 that occurs 120 min after training in the object recognition task. Further, the infusion of NA in CA1 after inhibition of NTS, PGi or LC; or of NMDA in LC after inhibition of NTS or PGi promotes the BDNF increase seen 120 min after object recognition training. Thus, it is concluded that the activation of NTSPGi- LC-Hippocampus pathway is necessary for consolidation of the object recognition memory, and hippocampal BDNF is involved in this process.
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Sanchez, Deborah S. "Supply control and product differentiation effects of European protected designations of origin cheeses." Thesis, Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/928.

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Palhares, de Miranda Ana Luisa. "Recherches sur les effecteurs de la biosynthèse de la prostacycline (PGI 2) de la thromboxane A 2 (TXA 2), et du facteur anti-thromboxane synthetase ("Fats")." Toulouse, INPT, 1986. http://www.theses.fr/1986INPT031G.

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Effets de composes organiques de synthese et de produits biologiques sur la biosynthese du facteur antithromboxane synthetase par le coeur isole de lapin. Un derive amino pyridazinique inhibe la biosynthese de la thromboxane a2 et stimule celle de la prostacycline et du "fats". La nicotine inhibe la biosynthese de la prostacycline, alors que la cotinine la stimule. Cette possibilite de modifier la biosynthese du "fats" par des produits biologiques pourrait etre une recherche interessante en pharmacologie et en therapeutique
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Swan, Michael Kenneth. "The pursuit of crystal structures in four systems : the complex of ribosomal protein S4 withmRNA, π initiator protein in complex with DNA and PGI from two archaea." Thesis, University of Sussex, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399820.

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Li, Qian. "Evaluation of Parking Guidance Information System with Multi-agent Based Simulation." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188568.

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20

Peng, Wendi Surveying &amp Spatial Information Systems Faculty of Engineering UNSW. "Roles of factors in simulation of parking guidance and information systems." Publisher:University of New South Wales. Surveying & Spatial Information Systems, 2008. http://handle.unsw.edu.au/1959.4/42788.

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The Parking Guidance and Information (PGI) system is an important application of Intelligent Transport System (ITS), which has been shown to be an effect service for traffic information and parking management. The roadside Variable Message Sign (VMS) board has been the usual media for the publication of parking information in early PGI systems, and its performance over the years has been studied via simulations and questionnaire surveys. However, survey results show significant discrepancies across various traffic networks in different areas. More recently, parking information services have become available on other media such as mobile and in-vehicle devices. In contrast to VMS-based systems, PGI systems based on new media, especially the in-vehicle class of devices, have not been studied separately. This thesis aims to conduct research into the performance of PGI systems based on invehicle devices, by simulating and comparing a VMS-based PGI system with a Vehicle On-Board Device (VOBD)-based PGI system. A specially designed simulator utilising a routing algorithm known as the Ad hoc On-Demand Distance Vector (AODV) routing protocol in computer networks, has been created in MATLAB. The simulation minimises the influence of specific structures of traffic networks that may be found in some networks, but not others. This is done by simulating a grid-based road network where the capacities of parking stations and their geographic distribution are randomly allocated within specific zones, and the parking demand in each run of simulations is variable load. The results of simulations, including the information reliability, reduction of travel time, demand on on-street parking and the utilisation rates of parking stations, are analysed for multiple scenarios where the compliance rate, the information update policy and the strategy of human behaviour are varied. The analyses reveal a significant advantage of VOBD-based PGI systems over VMS-based PGI systems in terms of the quality of information and the reduction of travel time. At the same time, the analyses highlight the limitations of a PGI system when the demand and supply of parking stations is not appropriately balanced.
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MORAES, Eloisa Basto Amorim de. "Processos de licenciamento de pólos geradores de viagens: o estudo de caso do Recife-PE." Universidade Federal de Pernambuco, 2008. https://repositorio.ufpe.br/handle/123456789/4973.

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Made available in DSpace on 2014-06-12T17:35:15Z (GMT). No. of bitstreams: 2 arquivo2204_1.pdf: 2245942 bytes, checksum: df0b37ff2780747f33cf10015d9e5bc6 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2008
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
O objeto de estudo dessa dissertação são os processos de licenciamento de Pólos Geradores de Viagens PGVs.. São enfocados os aspectos legais e técnicos que os analistas dispõem atualmente para emitir os pareceres técnicos na aprovação e licenciamento de empreendimentos considerados de impacto principalmente a análise visando a atração e geração de viagens. Considerado um processo administrativo, os licenciamentos de PGVs devem obedecer os princípios fundamentais da legalidade, da impessoalidade, da moralidade da publicidade e da eficiência (Brasil, 1988). Este trabalho se propõe a contribuir com o processo administrativo municipal de licenciamento de PGVs diante da diversidade de empreendimentos que podem ser classificados como PGVs, da crescente demanda de processos de licenciamento nas instâncias municipais competentes e na observação direta de atividades que se instalam sem que aparentemente essas medidas mínimas sejam cumpridas.A pesquisa empírica foi baseada no estudo de caso de licenciamento de PGVs em Recife-PE. Para coleta de dados foram utilizados os instrumentos de entrevistas e questionários bem como colhidas informações em documentos oficiais, legislação aplicada e em registros de tramitação de processos de empreendimentos de impacto.Os resultados apontam que apesar da legislação ser criteriosa e detalhada a mesma não encontra respaldo técnico e organizacional por parte do órgão gestor para sua aplicação. Não há instrução de procedimentos administrativos nem rotinas pré-estabelecidas para análise do processo, sendo os mesmos adotados pelos técnicos, por experiência própria Não foi verificado ainda o estabelecimento de prazo para tramitação de processos de análise especial de PGV. Não existe instrumento de acompanhamento após a implantação do empreendimento
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22

Reddy, Keerthi, Mary Kearns, Santiago Alvarez‐Arango, Ismael Carrillo‐Martin, Nathaly Cuervo‐Pardo, Lyda Cuervo‐Pardo, Ves Dimov, et al. "Youtube and Food Allergy: An Appraisal of the Educational Quality of Information." Digital Commons @ East Tennessee State University, 2018. https://doi.org/10.1111/pai.12885.

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Background: Food allergy affects an estimated 8% of children and 3% of adults in the United States. Food‐allergic individuals increasingly use the web for medical information. We sought to determine the educational quality of food allergy YouTube videos. Methods: We performed a YouTube search using keywords “food allergy” and “food allergies”. The 300 most viewed videos were included and analyzed for characteristics, source, and content. Source was further classified as healthcare provider, alternative medicine provider, patient, company, media, and professional society. A scoring system (FA‐DQS) was created to evaluate quality (−10 to +34 points). Negative points were assigned for misleading information. Eight reviewers scored each video independently. Results: Three hundred videos were analyzed, with a median of 6351.50 views, 19 likes, and 1 dislike. More video presenters were female (54.3%). The most common type of video source was alternative medicine provider (26.3%). Alternative treatments included the following: water fast, juicing, Ayurveda, apple cider, yoga, visualization, and sea moss. Controversial diagnostics included kinesiology, IgG testing, and pulse test. Almost half of the videos depicted a non‐IgE‐mediated reaction (49.0%).Videos by professional societies had the highest FA‐DQS (7.27). Scores for videos by professional societies were significantly different from other sources (P < .001). There was a high degree of agreement among reviewers (ICC = 0.820; P < .001). Conclusion: YouTube videos on food allergy frequently recommend controversial diagnostics and commonly depict non‐IgE‐mediated reactions. There is a need for high‐quality, evidence‐based, educational videos on food allergy.
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23

Demerjian, Jacques. "Services d'autorisation et Intégration au protocole d'attribution dynamique des adresses." Paris, ENST, 2004. http://www.theses.fr/2004ENST0036.

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La sécurité est un enjeu majeur des technologies numériques modernes. Avec le développement de l'Internet, les besoins de sécurité sont de plus en plus importants. Le développement d'applications Internet telles que le commerce électronique implique de nouveaux besoins comme, l'identification des entités communicantes, l'authentification des entités, l'anonymat du propriétaire du certificat, la procuration, etc. Qu'il s'agisse de données médicales, fiscales ou bancaires, le besoin en sécurité est essentiel afin de crédibiliser le système, tout en respectant à la fois les besoins des utilisateurs et des applications. Cette sécurité a néanmoins un prix : celui de l'établissement de la confiance entre les partenaires en communication. La confiance des utilisateurs passe par la sécurisation des transactions, par exemple au moyen d'une procédure de certification, et la reconnaissance des signatures électroniques. Malgré la diversité des certificats numériques existants (certificat d'identité X509, SPKI, certificat d'attributs, etc. ), ils sont encore limités, génériques et répondent ainsi insuffisamment aux besoins spécifiques des applications électroniques et des utilisateurs. D'où la nécessité de spécifier une nouvelle approche pour la génération de certificats numériques répondant à ces exigences, légers, simplifiés et plus ouverts que ceux existants. Les travaux de recherche présentés dans cette thèse consistent à proposer une nouvelle approche pour la génération de certificats numériques pour contribuer aux services d'autorisation, puis à intégrer cette contribution au protocole d'attribution dynamique des adresses DHCP afin de renforcer sa sécurité. ﷡﷡﷡﷡﷡
Security is a major stake of modern numerical technologies. With the development of the Internet, the needs for security are increasingly becoming more important than ever before. The development of Internet applications such as e-business, medical applications or videoconference, implies new needs such as, identification of the communicating entities, integrity of the exchanged messages, confidentiality of the transaction, authentication of the entities, anonymity of the certificate owner, procuration, etc. Whether they are medical, tax or banking related data, the requirement in security is essential in order to give credibility to the system, while respecting at the same time users' and applications' needs. This security has nevertheless a price: that of the establishment of trust between communicating partners. Users' trust goes through transactions security, for example by means of a certification procedure, and the recognition of electronic signatures. Despite the diversity of existing certificates (X. 509 identity certificate, SPKI, attributes certificate, etc), they are still limited, generic and thus, meet insufficiently the specific needs of electronic applications and users. Hence, the need for specifying a new approach for the generation of certificates answering these requirements, light, simplified and more open than those existing. The research tasks presented in this thesis consist in proposing a new approach for the generation of certificates to contribute to the authorization services, then to integrate this contribution to DHCP (Dynamic Host Configuration Protocol) in order to reinforce its security
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Pérotin, Pascal. "Les Progiciels de Gestion Intégrés, instruments de l'intégration organisationnelle? Etude d'un cas." Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2004. http://tel.archives-ouvertes.fr/tel-00008966.

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Les Progiciels de Gestion Intégrés (PGI) sont aujourd'hui la clef de voûte du Système d'Information de gestion de la majorité des entreprises. Ils sont considérés comme des vecteurs du changement organisationnel et censés contribuer à améliorer l'intégration organisationnelle. Il existe cependant une grande incertitude sur le bon déroulement des projets.

En effet, les différentes remises en cause (des tâches, des métiers, du pouvoir ou de la finalité de l'entreprise) sont potentiellement sources de conflit, reflet des divergences d'intérêt et de représentation des différents acteurs concernés. Dans ces conditions, chaque décision peut être l'objet d'une négociation entre les parties prenantes, alimentant ainsi l'incertitude sur le résultat du processus de mise en place.

L'analyse en profondeur d'un cas de mise en place d'un PGI a toutefois permis de vérifier que cette technologie permet de réaliser l'objectif d'intégration, au prix d'une réduction très forte des marges de manœuvre des acteurs. La thèse met en évidence, dans les circonstances spécifiques observées, la stratégie employée par la direction du projet et les facteurs déterminants du succès. Ainsi le PGI, associé au BPR (Business Process Reengineering), joue-t-il le rôle d'un outil de gestion aux mains des dirigeants afin de réaliser un changement organisationnel. Cette vision téléologique du changement met en avant le potentiel du PGI pour intégrer et standardiser l'organisation.
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Kaukonen, R. (Risto). "Sulfide-poor platinum-group element deposits:a mineralogical approach with case studies and examples from the literature." Doctoral thesis, University of Oulu, 2008. http://urn.fi/urn:isbn:9789514289545.

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Abstract Sulfide-poor deposits of platinum-group elements (PGE) occur in two main types: silicate-type and oxide-type. In the silicate-type mineralization PGE form discrete platinum-group minerals (PGM) that occur as inclusions in various silicate minerals. In the oxide-type mineralization PGM may have different modes of occurrence. They may be associated with silicates or they may occur as inclusions in chromite, magnetite or ilmenite, for example. In some cases they may even be associated with base metal sulfides. The approach chosen in this work is mainly a mineralogical one. PGM parageneses, their modes of occurrence and associations with other minerals were studied from different deposits. These are then compared to some well-recorded examples of PGE deposits. The case studies presented, the Duluth Complex in Minnesota, U.S.A., the Hanumalapur Complex in Karnataka, India, and the Penikat Layered Intrusion in northern Finland, are examples that illustrate the multitude of possibilities regarding PGE mineralization versus the traditional approach where any significant quantities of PGE are supposed to occur only in association with base metal sulfides. As the traditional orthomagmatic and hydrothermal models cannot explain the genesis of some sulfide-poor PGE occurrences, a new theory of PGE mineralization was developed. This “redox theory” is an attempt at explaining the association of PGE with various oxide minerals, most importantly chromite.
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26

Marino, Dante. "Screening of Germplasm Accessions from the Brassica Species for Resistance against PG3 and PG4 Isolates of Blackleg." Thesis, North Dakota State University, 2011. https://hdl.handle.net/10365/29053.

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Blackleg is a disease of canola and rapeseed cultivars that is caused by the fungus Leptosphaeria maculans (Desm.) Ces. & de Not., and it is by far the most destructive pathogen of canola in North America. In recent years, blackleg strains belonging to pathogenicity groups (PG) 3 and 4 have been discovered in North Dakota. Recent outbreaks of the disease have added a sense of urgency to characterize the risk these new strains represent for the canola industry and to identify sources of resistance against them. Thus, the objectives of this study were to screen germplasm collections of Brassica rapa, B. napus. and B. juncea for their reaction to PG3 and PG4 and to evaluate the reaction of a sample of currently used canola commercial cultivars grown in North Dakota to PG3 and PG4 as means to estimate the risk these new strains represent. All canola germplasm and commercial cultivars were evaluated in replicated trials in greenhouse conditions using cotyledon bioassays. In 2009 and 2010, the effect of these strains, using five inoculation sequences, on the reaction of canola seedlings was also evaluated. Field trials were not conducted because of the limited geographical distribution of the new strains. No adequate sources of resistance were identified among the 277 B. rapa and 130 B. napus accessions evaluated; however, 22 of the 406 accessions of Brassicajuncea evaluated were considered to have moderate levels of resistance. B. juncea seedlings that survived these inoculations were self-pollinated and their progeny (F1) were also screened. As before, surviving seedlings were self-pollinated. These F2 seeds are the elite materials that could be used in future breeding programs. The complementary study evaluating the role of sequence inoculations in reaction of canola seedlings to blackleg indicated that an increased susceptibility to PG3 occurred when seedlings were first inoculated with PG4; however, reaction to PG4 was not enhanced by a prior inoculation with PG3. All 75 commercial cultivars evaluated were susceptible to PG3 and PG4, indicating that the risk these new strains represent to the canola industry of the region is serious. Further, when a subsample of 16 cultivars were challenged with PG2, they were either resistant or moderately resistant, suggesting the ratings the industry are using relate to reaction of those cultivars to PG2 but not to the new strains; thus, growers should use caution when using these ratings while deciding on which cultivars to plant.
North Dakota State University. Department of Plant Pathology
USDA North Central Canola Research Program
Northern Canola Growers Association
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27

Pajvani, Mehulkumar. "Universal celebrity endorser and interaction between perceived celebrity image (PCI) And perceived brand image(PBI) across national boundaries." Thesis, University of Leeds, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511170.

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28

Hinarejos, Campos M. Francisca. "Seguridad en redes de computación ubicua: contribución a la validación de credenciales." Doctoral thesis, Universitat Politècnica de Catalunya, 2010. http://hdl.handle.net/10803/77916.

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Technology progress in both user devices and networks allows communications anytime and anywhere. New communication environments offer a wide range of possibilities to users, but also generate new threats. For this reason, it is necessary to establish measures to find out who is establishing a communication and what actions is authorized to do. Currently proposed solutions in the literature are not completely adapted to the new features such as user mobility, network disconnections and constraints of devices and networks. Many of the existing proposals have focused in providing specific solutions to particular scenarios, but they do not consider a global heterogeneous scenario. Therefore, it is necessary to design security mechanisms able to adapt themselves to new scenarios. In this sense, digital certificates are a standardized and widely used solution. Digital certificates enable performing user authentication and authorization in a distributed way. The problem is that ubiquitous environments complicate the process of digital certificates validation. This complexity could result in a service being not accessible. The goal of this thesis is to contribute in making ubiquitous scenarios more secure. More specifically, the work proposes solutions for reducing the credential validation cost and for improving the availability of authentication and authorization services. In first place, we propose a solution for credential validation that works properly in environments with connection to on-line servers and also in environments where the connection to servers is sometimes not possible. In second place, we propose a cascade revocation system where the delegation is partially centralized. Delegation provides high flexibility to authorization systems, but adds complexity to the system. Our proposal reduces the burden on the verifier-side. In third place, we propose a revocation system for delegation chains based on prefix codes. This proposal deals with the problem of centralization of the previous proposal. In particular, the decentralized solution presented keeps the load reduction achieved in the partially centralized proposal, and also enables dynamic delegation and distribution of revocation data. While the user is connected, revocation data distribution can be done with a certificate revocation list. However, in scenarios where the connection can be lost temporally, this might not be possible. To address this issue, we have proposed a system in which users can perform the functions of revocation servers without being trusted entities. This will allow increasing the availability of validation service, and reduce resource consumption. Each proposal has been analyzed and compared with existing solutions to verify the improvements achieved.
El avance tecnológico tanto de los dispositivos de usuario como de las redes permite que se puedan establecer comunicaciones en cualquier momento y en cualquier lugar. Si bien estos entornos ofrecen un gran abanico de posibilidades a los usuarios, también es cierto que generan nuevas amenazas. Por este motivo, son necesarias medidas que permitan saber con quién se está estableciendo la comunicación y qué acciones se pueden autorizar. Las soluciones propuestas en la literatura no se adaptan completamente a las nuevas características de movilidad, desconexión y limitaciones tanto de los dispositivos como de las redes. De hecho, muchas de las propuestas existentes se han centrado en ofrecer soluciones concretas a escenarios particulares, sin tener en cuenta que el usuario puede entrar a formar parte de entornos heterogéneos. Por lo tanto, se hace necesario diseñar mecanismos de seguridad que conviviendo con los estándares vigentes, se adapten a los nuevos escenarios. En este sentido, los certificados digitales son una solución estandarizada y ampliamente extendida. Los certificados digitales permiten llevar a cabo tanto la autenticación como la autorización de un usuario de forma distribuida. Sin embargo, las características de los entornos ubicuos complican el proceso de validación de certificados. Esta complejidad podría llevar a que no se puediera acceder a los servicios. El objetivo de esta tesis es contribuir a aumentar la seguridad en entornos ubicuos. Más concretamente, se proporcionan soluciones para reducir la carga en la validación de credenciales y aumentar la disponibilidad de los servicios de autenticación y autorización. En primer lugar se propone un sistema de verificación de credenciales que se adapta para funcionar tanto en entornos con conexión a servidores on-line, como en sistemas off-line. Por otra parte, el proceso de delegación en sistemas de autorización, aporta una gran flexibilidad a estos entornos, pero a su vez añade complejidad al sistema. Para reducir esta carga sobre el verificador se propone un sistema de revocación en cascada con delegación centralizada. Sin embargo, esta centralización del servicio limita la escalabilidad y flexibilidad de la solución. Para dar solución a ese inconveniente, se ha propuesto un sistema de revocación en cadenas de delegación basado en códigos prefijo. Esta solución permite mantener la reducción de la carga en la validación lograda en la propuesta centralizada, y además, hace posible la delegación dinámica y la distribución de la información de revocación. Esta distribución puede realizarse a través de listas de revocación de credenciales. En redes con desconexión temporal esta información podría no estar accesible. Para solventarlo, se ha propuesto un sistema en el que los usuarios pueden realizar las funciones de servidores de revocación sin ser entidades de confianza. De esta forma se permite aumentar la disponibilidad del servicio de validación, y reducir el consumo de los recursos. Cada una de las propuestas realizadas se ha analizado para verificar las mejoras proporcionadas frente a las soluciones existentes. Para ello, se han evaluado de forma analítica, por simulación y/o implementación en función de cada caso. Los resultados del análisis verifican el funcionamiento esperado y muestran las mejoras de las propuestas frente a las soluciones existentes.
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Liu, Hailong, Wenhua Qi, Qishan Zhang, and Jinpei Wu. "PKI/PMI AND SMART TOKENS IN HEALTHCARE INFORMATION SYSTEMS." International Foundation for Telemetering, 2003. http://hdl.handle.net/10150/606668.

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International Telemetering Conference Proceedings / October 20-23, 2003 / Riviera Hotel and Convention Center, Las Vegas, Nevada
While healthcare industry is striving to achieve e-health systems for improvements in healthcare quality, cost, and access, privacy and security about medical records should be considered carefully. This paper makes a deep study of Public Key Infrastructures (PKIs) and Privilege Management Infrastructures (PMIs) and how they can secure e-health systems. To access resources, e.g. patient records, both authentication and authorization are needed, so public key certificates and attribute certificates are both required to protect healthcare information. From a typical medical scenario, we see not only static but also dynamic permissions are required. Dynamic authorization maybe the most complex problem in e-health systems.
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30

Glays, Brent. "War Pig." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/theses/1880.

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War Pig is a series of short stories and poems that follow the protagonist, Christopher Lambert, as he embarks on training exercises and multiple deployments. It culminates with Lambert coming home and reintegrating into civilian life.
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31

Raberi, Araz. "Genetic contributory factors to infertility." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:4363762b-6c0b-465c-925a-ecc86e772220.

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Introduction: In recent years, the average age of first reproduction has risen significantly, the mean now standing at around 30 years in many countries. The adverse effects of maternal age on fertility and reproduction have been well documented. However, the influence of paternal age on fertility, reproduction and postnatal health is relatively poorly understood, and 50% of all male infertility cases are classed as idiopathic or unexplained infertility. Methods: The aim of this study was to investigate factors that contribute to male infertility, split into two main parts. The first part focused on analysing data collected from patients who had undergone fertility treatment to assess the influence of different factors on infertility, especially at the genome level. The second part attempted to deal with some of the technical challenges of screening and diagnostic methods to study the genome, with the aim of providing tools that would assist future studies in pinpointing genetic factors responsible for infertility, especially in cases of idiopathic infertility. Results: Based on data from the first part of the study, it was determined that advanced paternal age can affect sperm progressive motility, sperm DNA integrity and the fertilisation rate of in vitro fertilisation (IVF) cycles, as well as the development of embryos. Direct analysis of sperm DNA fragmentation (SDF) and degradation levels revealed an association between elevated SDF and impaired embryo development. Furthermore, a correlation was shown between chromosome aneuploidy and variance in SDF and sperm DNA degradation. Moreover, aneuploidy can influence abnormal sperm morphology and consequently also progressive motility. Also, embryo development rate of IVF cycles on day three, demonstrated a significant decline in cycles where the sperm used for fertilisation had a high aneuploidy rate, which can highlight the reduced developmental capacity of aneuploid embryos. From the lifestyle factors assessed, only alcohol consumption significantly correlated with the sperm DNA damage. Therefore, poor semen quality may highlight damage that has been incurred by the sperm DNA. When the semen quality is suboptimal, the intracytoplasmic sperm injection (ICSI) technique is suggested as a standard strategy to improve the prognosis of ART. However, when the progressive motility is poor, the ICSI approach is not as effective. Based on our findings and in line with other studies, the only sperm parameter that can be affected by paternal age is sperm motility, which could be an indicator of SDF. Therefore, the decline in ICSI fertilisation rate in patients with impaired sperm progressive motility could be due to sperm DNA damage, and even ICSI cannot improve the fertilisation rate considerably. Discussion: The aim of the second part of this project was to establish a robust workflow for whole- genome amplification (WGA) and whole-genome sequencing of single cells to improve the coverage rate and fidelity, with the aim of providing means of detecting any mutation in the genome that might be responsible for reduced embryonic developmental competence. Towards this end, the efficiencies of two different WGA protocols (REPLI-g and TruePrime) were compared. Multiple technical factors required optimisation in order to create a suitable protocol. Our results demonstrated the overall superiority of REPLI-g compared to TruePrime in almost all the assessed parameters. The amplification rate of REPLI-g was much faster than that of TruePrime, and prolonged incubation led to overamplification and an increased duplication rate. However, the TruePrime method has a slower amplification rate and therefore, by increasing the incubation time, it was possible to improve the quality of the data. The modified protocol with reduced volume also had the most promising outcome in terms of the data produced, and could fulfil our expectations by being fast, cost-effective and efficient. Conclusion: In conclusion, the results from the first part of this study confirmed the negative impact of male age on assisted reproductive treatments, which can result in decreased success rates of fertilisation. Other factors such as sperm DNA damage may also contribute to this age effect, suggesting that assessing this parameter prior to fertility treatment, and attempting to mitigate elevated levels of sperm DNA damage, may be of value to older patients. Additionally, overcoming the technical challenges in studying genetic contributory factors in infertility is a promising step toward better understanding of the mutations and variations that are involved in this phenomenon.
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Henning, Sebastian, Laura Kühn, Juan Herranz, Maarten Nachtegaal, Rene Hübner, Matthias Werheid, Alexander Eychmüller, and Thomas Justus Schmidt. "Effect of Acid Washing on the Oxygen Reduction Reaction Activity of Pt-Cu Aerogel Catalysts." Elsevier, 2018. https://www.sciencedirect.com/science/article/pii/S001346861730484X.

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Developing highly active and durable oxygen reduction reaction (ORR) catalysts is crucial to reduce the cost of polymer electrolyte fuel cells (PEFCs). To meet those requirements, unsupported Pt-Cu alloy nanochains (aerogels) were synthesized by a simple co-reduction route in aqueous solution and their structure was characterized by X-ray absorption spectroscopy and STEM-EDX. These catalysts exceeded the ORR activity of commercial Pt/C catalysts by more than 100 % in RDE experiments and met the US DOE targets, thereby qualifying as very promising materials. The behavior of Pt-Cu aerogels under PEFC operation conditions was mimicked by acid washing experiments which showed that the Cu content in the alloy phase and ORR activity decrease through this step. Comparing composition, structure and ORR activity for various specimens, the Cu content in the alloy phase was identified as the main descriptor of ORR activity. An almost linear correlation was found between those two parameters and complemented by supporting data from the literature.
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Leopold, Teresa Ingeborg, and n/a. "The construction of a disaster destination : rebuilding Koh Phi Phi, Thailand." University of Otago. Department of Tourism, 2008. http://adt.otago.ac.nz./public/adt-NZDU20080430.100246.

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The popular tourist destination island of Koh Phi Phi Don, Thailand was heavily affected by the Indian Ocean Tsunami in December 2004, which resulted in a destroyed tourism infrastructure and complete downturn of tourism. Extensive recovery and rebuilding work by emerging community groups, returned locals, international volunteers and Thai government units provided an efficient but hasty reconstruction of the destination. Ethnographic research conducted in the community provided insights into the complex stakeholder interactions and their roles and influences on the reconstruction of the community. The community�s level of vulnerability on Koh Phi Phi Don was influenced by social processes and interactions during the destination�s recovery process as the various stakeholders (e.g. government vs. locals) had differing perceptions of the island�s economic, environmental and social vulnerability. These disputes are grounded in different social time processes, particularly illustrated through land law disputes among locals, landowners and the government. Other factors which influenced the reconstruction of Koh Phi Phi as a tourist destination were pre-tsunami conditions (past overdevelopment), the empowerment of the community, the reconstructed place identity, various anniversary celebrations and the early warning system. A model is suggested to illustrate and discuss Koh Phi Phi Don as a disaster destination, which provides insights into the dynamics which govern a destination�s post-disaster recovery period. Thus, it illustrates how stakeholder interaction is influenced by distinct understandings of the multiple notions of vulnerability. Furthermore, this study establishes essential links between disaster and tourism theories and suggests an extended tourism disaster management framework, which calls for an inclusion of post-recovery processes.
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Cherer, Evandro de Quadros. "A noção de pai em psicanálise do declínio ao pai morto." reponame:Repositório Institucional da UnB, 2018. http://repositorio.unb.br/handle/10482/34156.

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Tese (doutorado)—Universidade de Brasília, Instituto de Psicologia, Programa de Pós-graduação em Psicologia Clínica e Cultura, 2018.
Às voltas com as mudanças familiares na sociedade vienense, no final do século XIX, e com a sexualidade histérica, Sigmund Freud atentou-se para a questão do pai, inserindo-a no campo da psicanálise. A propósito disso, o presente estudo consiste em uma proposta de investigação teórica sobre a questão do pai à luz da psicanálise, tendo como objetivo investigar a noção de pai, redimensionando-a no campo da psicanálise. Particularmente, buscou-se que os operadores conceituais da psicanálise fossem reconsiderados, fundamentalmente no que diz respeito à questão do pai em relação ao declínio da imago paterna e suas eventuais repercussões na constituição subjetiva. Acerca disso, percorreu-se como a noção de pai surgiu, desenvolveu-se e foi trabalhada na obra freudiana. De início, o pai foi apreendido enquanto sedutor e associado à etiologia das neuroses. Entretanto, a teoria da sexualidade infantil promoveu uma torção, deslocando o pai para o complexo de Édipo. Nesse, o pai seria o interditor do objeto de desejo e, simultaneamente, o ideal, na medida em que detém para si a mãe ao possuir o falo. Essa relação ambivalente, ou seja, de rivalidade e idealização, foi nomeada de complexo paterno, aspecto fundamental na noção de pai. Situando essa questão nas origens da humanidade, Freud formulou o mito do parricídio inaugural. O Urvater, o pai primordial, foi assassinado pelos filhos e, mesmo morto, tornou-se mais forte que se vivo estivesse. Semelhantemente, Moisés teria sido assassinado pelos judeus ao conduzi-los à terra prometida. Nas três principais versões freudianas do pai (Édipo, Urvater e Moisés), o parricídio está presente. O pai, o Um da exceção, é, a rigor, o pai morto, aquele cujo lugar ninguém está efetivamente à altura. De modo semelhante, investigou-se o declínio do pai e a problemática de suas eventuais repercussões na obra do jovem Lacan, na qual repercussões foram tributadas ao declínio da família paternalista, bem como eventuais falhas na constituição subjetiva atribuídas ao pai no seio familiar. Foi visto que essa lógica da contração familiar como prejudicial à constituição subjetiva está presente mesmo atualmente. Contrapondo-se a essa perspectiva, a problemática do pai também foi considerada em o “retorno a Freud” feito por Lacan, período no qual a noção de pai passou a ser apreendida a partir do caráter linguajeiro, sendo cunhado o conceito de Nome-do-Pai enquanto suporte da função simbólica. Distanciando-se do familialismo, é numa função lógica que o pai foi situado. Com isso, esta tese procurou investigar o que é o pai em psicanálise, essencialmente na teoria freudiana e nas (re)leituras produzidas por Lacan, contrapondo-se ao uso que se faz atualmente das noções de “enfraquecimento” ou “declínio” da função paterna, redimensionando essas questões no campo da psicanálise e defendendo a hipótese segunda a qual há uma radical distinção entre os pais, que estão sempre aquém, e a função paterna enquanto tal.
In view of family changes in Viennese society at the end of the nineteenth century, and with hysterical sexuality, Sigmund Freud occupied himself at the question of the father, inserting it into the field of psychoanalysis. In this regard, the present study consists of a theoretical research on the question of the father in the light of psychoanalysis, aiming to investigate the notion of father, redimensioning it in the field of psychoanalysis. Particularly, it has tried to reconsider the conceptual operators of psychoanalysis, fundamentally what it comes to the question of the father in relation to the decline of paternal imago and its possible repercussions on subjective constitution. Regarding this, it was studied how the idea of father arose, developed and was worked out in Freudian literature. At first, the father was apprehended as seductive and associated with the etiology of the neuroses. However, childhood sexuality promoted a twist, shifting the father to the Oedipus complex, in which the father would be the interdictor of the object of desire and, simultaneously, the ideal, considering that he holds for himself the mother as he possesses the phallus. This ambivalent relation, that is, of rivalry and idealization, was named paternal complex, fundamental aspect in the notion of father. Contextualizing this question in the origins of humanity, Freud formulated the myth of the inaugural parricide. Urvater, the primordial father, was murdered by his sons and, even dead, became stronger than if he were alive. Similarly, Moses have been murdered by the Jews when leading them to the promised land. In the three major Freudian versions of father (Oedipus, Urvater, and Moses), parricide is present. The father, the One of the exception, is, strictly speaking, the dead father, the one whose place no one is effectively up to. In a similar way, the present study also investigated father's decline and the problematic of its eventual repercussions in the work of young Lacan, in which repercussions were tributed to the decline of the paternalistic family, as well as possible failures in the subjective constitution attributed to the father within the family. It has been seen that this logic of family contraction as detrimental to the subjective constitution is present even today. In contrast to this perspective, the father's problematic was also considered in Lacan's "return to Freud", a period in which the notion of father became apprehended by the character of langage, and the concept of the Name-of-Father was coined as support of the symbolic function. Distancing itself from familialism, it was in a logical function that the father was placed. Thus, this thesis sought to investigate what the father is in psychoanalysis, essentially in Freud's theory and in the (re)readings produced by Lacan, in opposition to the current use of notions of "weakening" or "decline" of function paternal, redimensioning these issues in the field of psychoanalysis and defending the hypothesis according which there is a radical distinction between the fathers, who always fall short, and the paternal function.
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35

Mitby, Amy K. (Amy Kirsten) 1979. "A PCI/PCI-X test card for I/O system verification." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/87243.

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36

Ilavský, Ľubomír. "Řadič sběrnice PCI pro vývojovou kartu s obvodem FPGA." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2009. http://www.nusl.cz/ntk/nusl-236661.

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This thesis deals with the communication on the PCI bus and the design of controllers for the PCI card with FPGA circuit. The introduction shows the functionality and structure of FPGA circuits, followed by description of the principle of communication through the PCI bus. After an analysis of the PCI the thesis describes a design of controllers for a target card and lets the reader get acquainted with its different parts. In the process of implementation carefully examines the structure and operation of individual blocks of PCI controller. In the following part the thesis shows the process of implementation and testing of the final solution using the educational card with FPGA circuit.
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37

Kalavri, Vasiliki. "Integrating Pig and Stratosphere." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-98786.

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MapReduce is a wide-spread programming model for processing big amounts of data in parallel. PACT is a generalization of MapReduce, based on the concept of Parallelization Contracts (PACTs). Writing efficient applications in MapReduce or PACT requires strong programming skills and in-depth understanding of the systems’ architectures. Several high-level languages have been developed, in order to make the power of these systems accessible to non-experts, save development time and make application code easier to understand and maintain. One of the most popular high-level dataflow systems is Apache Pig. Pig overcomes Hadoop’s oneinput and two-stage dataflow limitations, allowing the developer to write SQL-like scripts. However, Hadoop’s limitations are still present in the backend system and add a notable overhead to the execution time. Pig is currently implemented on top of Hadoop, however it has been designed to be modular and independent of the execution engine. In this thesis project, we propose the integration of Pig with another framework for parallel data processing, Stratosphere. We show that Stratosphere has desirable properties that significantly improve Pig’s performance. We present an algorithm that translates Pig Latin scripts into PACT programs that can be executed on the Nephele execution engine. We also present a prototype system that we have developed and we provide measurements on a set of basic Pig scripts and their native MapReduce and PACT implementations. We show that the Pig-Stratosphere integration is very promising and can lead to Pig scripts executing even more efficiently than native MapReduce applications.
Att skapa effektiva applikationer i MapReduce eller PACT kråver goda programmeringskunskaper och djup förståelse utav systemens arkitektur. Flera högnivå-språk har utvecklats för att göra de kraftfulla systemen tillgängliga för icke-experter, för att spara utvecklingstid och för att göra applikationernas kod lättare att förstå. Ett utav de mest populära systemen för högnivå-dataflöden är Apache Pig. Pig överkommer Hadoops ett-input och tvånivå-begränsningar och låter utvecklaren skriva SQL-liknande skript. Dock är Hadoops begränsningar fortfarande närvarande i backend-systemet och lägger till ett synligt tillägg till exekutionstiden. Pig är för nuvarande implenterat ovanpåHadoop, dock har det designats för att vara modulärt och oberoende utav exekutionsmotorn. I det här exjobbs-projektet presenterar vi integration utav Pig med ett annat framework för parallel dataprocessering, Stratosphere. Vi visar att Stratosphere har önskade egenskaper som signifikant förbättrar Pigs prestanda. Vi presenterar en algoritm som översätter Pig Latin-skript till PACT-program som can köras påNepheleexekutionsmotorn. Vi presenterar ocksåett prototypsystem som vi har utvecklat och vi bidrar med mätningar utav ett set av grundläggande Pigskript och deras MapReduce och Pact-implementationer. Vi visar att Pig-Stratosphere-integrationen är väldigt lovande och kan leda till att Pigskript exekuteras mer effektivt än MapReduce applikationer.
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38

Almeida, Fabiana Abi Rached de. "A sombra do Pai." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/270178.

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Orientador: Suzi Frankl Sperber
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
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Resumo: A proposta do presente trabalho é articular um estudo comparativo entre o romance Lavoura Arcaica, de Raduan Nassar (1975), e o filme homônimo, LavourArcaica de Luiz Fernando Carvalho (2001). Atualmente, não podemos mais negar a influência das diversas formas de arte na vida moderna, principalmente, do cinema. A literatura influencia o cinema e o cinema a literatura. Mesmo sendo meios diferentes, há ressonâncias entre eles e que podem ser vistas até como obras complementares na medida em que há a possibilidade de serem analisadas uma com o auxílio da outra. Além das interseções que existem entre as diferentes formas de arte que já são por si só delicadas, há dificuldades que permeiam a majestade e complexidade dessas obras e, por isso, deparamo-nos, desde sempre, com questões do tipo: como falar sobre e mesmo absorver obras tão intensas? Como desvendar os mistérios dessas obras sem deturpá-las ou reduzí-las? Para tanto, nessa pesquisa, fizemos uso de alguns conceitos que mesclam a teoria da literatura, a teoria cinematográfica e a psicanálise de Freud e Lacan, principalmente; para que, assim, pudéssemos articular um estudo que fosse ao mesmo tempo "severo" e que preservasse os interstícios fundamentais e a poesia das obras.
Abstract: The proposal of this work is to articulate a comparative study between the romance To the left of the father, Nassar Raduan (1975), and the film, To the left of the father by Fernando Carvalho (2001). Today, we can no longer deny the influence of various forms of art in modern life, mainly of cinema. Literature influences the cinema and cinema, literature. Although they are different art forms, movie and romance can be seen as complementary works to the extent that there is the possibility of analising one on behalf of the other. In addition to the delicate intersections that exist between the various forms of art, there are difficulties which permeate the majesty and complexity of such works and therefore questions always turns up: how to talk about and even absorb so intense works? How to unravel the mysteries of such works without distort or reduce them? To do this research we use some concepts that merge into the theory of literature, film and, mainly, Freud's and Lacan's theorys of psychoanalysis; so that, by these means, we could articulate a study that is at the same time "severe" and that preserves the fundamental interstices and both work's poetry.
Mestrado
Literatura e Outras Produções Culturais
Mestre em Teoria e História Literária
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39

Haygert, Maria Lúcia Lemos. "De pai para filho." Florianópolis, SC, 2000. http://repositorio.ufsc.br/xmlui/handle/123456789/78697.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Antropologia Social
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O estudo etnográfico está centrado na mudança nas relações geracionais da agricultura familiar do Município de Quilombo, Oeste de Santa Catarina, precisamente nas famílias cujos filhos passaram pela Casa Familiar Rural Santo Agostinho. A pesquisa parte da idéia inicial de que o saber do pai, central para a legitimidade da autoridade paterna na organização familiar tradicional, está sendo questionado quanto a sua eficiência para reproduzir a família. A interferência do processo educativo da Casa Familiar Rural, ao proporcionar uma troca de saberes que introduz a possibilidade de manutenção e, talvez, ampliação do patrimônio familiar, propicia aos jovens uma certa autoridade. O resultado é a construção de espaços de diálogo entre a autoridade fragmentada do pai e as autoridades múltiplas, tecendo um novo território familiar.
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40

Gonçalves, Cristiane. "Interação pai-mãe-bebê." Florianópolis, SC, 2002. http://repositorio.ufsc.br/xmlui/handle/123456789/84319.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.
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A figura do pai, até os anos 60 era pouco expressiva no desenvolvimento infantil. A maioria das pesquisas concentram seus estudos nas características da interação mãe-bebê, cabendo ao pai, a responsabilidade apenas pelo sustento familiar. A partir de resultados de estudos que comprovaram a importância do papel dos pais no desenvolvimento social e afetivo do bebê, inverteu-se esse quadro. No entanto, no Brasil são raros os estudos que se dirigem a este ponto. Assim, esta pesquisa teve como objetivo analisar as interações pai-bebê em contextos específicos. Foi realizado o registro em vídeo, em ambiente natural, de três díades em quatro momentos de desenvolvimento: 1, 2, 3, 4 mês de idade de bebês entre 30 dias a 5 meses, onde foram analisados os episódios de domínio social, domínio didático e interação não efetivada, além de registrar alguns relatos dos pais sobre os aspectos gerais da situação e acontecimentos relevantes. Após 05 meses foi realizado um encontro final, examinando a experiência do pai, sua participação no desenvolvimento do filho, bem como, o depoimento das mães quanto a sua participação. Concluindo, foram identificadas interações iniciais como processos recíprocos de engajamento que tornaram-se mais freqüentes e complexas no decorrer dos meses, com o predomínio de episódios de domínio didático, além do prazer dos pais em participar dos cuidados dos filhos, mediados por uma atitude de amor paterno.
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41

Cuba, B. Elmer. "Estimación del PBI potencial y de la brecha del PBI: Perú 1970-1995." Economía, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/117258.

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42

Vu, Phuong Anh. "Gender stereotypes in story textbooks for primary school students in Vietnam /." Oslo : Institute for Educational Research, Universitetet i Oslo, 2008. http://www.duo.uio.no/publ/pfi/2008/77612/vu_thesis.pdf.

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43

Yang, Xing. "Higher education and the labour market in China : a case study of three universities in Shanxi province /." Oslo : Pedagogisk forskningsinstitutt, Universitetet i Oslo, 2008. http://www.duo.uio.no/publ/pfi/2008/74320/formalxpaper.pdf.

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44

Li, Fuhui. "School leadership training in China : a cultural perspective /." Oslo : Pedagogisk forskningsinstitutt, Universitetet i Oslo, 2007. http://www.duo.uio.no/publ/pfi/2007/58048/MasterThesis_FuhuiLi.pdf.

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45

Bilkyte, Jurgita. "Adult education and work life : a comparative study of Norway and Japan /." Oslo : Pedagogisk forskningsinstitutt, Universitetet i Oslo, 2008. http://www.duo.uio.no/publ/pfi/2008/76551/masterxsxtheses_jurgita_bilkyte.pdf.

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46

Awaleh, Mahad. "Child labour and access to education : an investigation of the situation in Bangladesh /." Oslo : Institute for Educational Research, Universitetet i Oslo, 2007. http://www.duo.uio.no/publ/pfi/2007/58409/MahadxAwalehxMasterxThesisxChildxLaborxinxBangladeshxUio.pdf.

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47

Shahjamal, Mirja Mohammad. "Student politics and quality of education : an exploratory study on Dhaka University /." Oslo : Institute for Educational Research, Universitetet i Oslo, 2007. http://www.duo.uio.no/publ/pfi/2007/60229/Thesis_final_Mirja.pdf.

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48

Wennberg, Lars. "Islet xenograft rejection : studies in the pig-to-rodents and pig-to-primate models /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-2835-5.

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49

Taylor, Faye. "Post disaster tourism development of Phi Phi Island : political economy and interpretations of sustainability." Thesis, University of Bedfordshire, 2012. http://hdl.handle.net/10547/280053.

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This research takes an interdisciplinary approach and includes aspects of applied geography, applied management, political economy, development studies, sociology and anthropology, in line with the tradition of progressive tourism studies. It seeks to resolve academic concern about the limited insight within existing bodies of knowledge into how sustainability and sustainable tourism development are conceptualised at a grassroots level by inhabitants and other stakeholders of tourism destinations (Redclift, 1987; Liu, 2003; Swarbrooke, 1999; Mowforth and Munt, 1998; Maida, 2007) and furthermore how these conceptualisations are shaped through expressions of political economy in a post-crisis context. The research aimed to evaluate how political economy and interpretations of sustainability affected post-disaster tourism redevelopment using the case study of Phi Phi Island in Thailand, which was devastated by the tsunami of December 2004. An interpretive philosophy informed the research design, in which primary data was gathered using an inductive mixed methodology. Methods included online research, comprising the design and operation of a tailored website to overcome geographical and access limitations; and offline methods such as visual techniques to monitor change and confirm opinions offered by participants of the research; in-depth face-to-face interviews with hand-picked stakeholders of Phi Phi's development; open-ended questionnaires with tourists; and extended answer Thai script questionnaires in order to overcome language barriers and present the 'Thai voice'. The primary data was gathered from April 2006-December 2011 including a period working at [information removed for anonymity purposes] University in Phuket (June-December 2006). Twenty-five themes emerged from the data, the most significant being the social impacts of tourism, environmental impacts of tourism, power relationships and future desires. It was found that the factor with the greatest influence over Phi Phi's development is the desire to develop the economy through tourism, and the philosophy underpinning the development is largely economic. The tsunami did not cause any significant reassessment of the tourism development trajectory, but served to uncover a range of conflicts and unlawful activity, resulting from powerful stakeholders pursuing their own interests and desired outcomes, in order to suit their own needs rather than those of the community as a whole. In terms of how sustainability is conceptualised by different stakeholder groups, it was found that the meanings attributed to sustainability in this context differ greatly to meanings elaborated within western ideological debates. Stakeholders' conceptualisations of sustainability were mapped against key debates within literature. How meanings differed between stakeholder groups was also examined and a definition for sustainable tourism development on Phi Phi was compiled encompassing a broad range of interests. The thesis provides a rare opportunity to see which political, economic and cultural factors shape the planning of tourism development and whether actual practice mirrors the principles of sustainability. For islanders, present needs are yet to be met and education was recommended to increase islanders' understanding of impacts and sustainability, as well as their skills and knowledge base to enable them to compete intellectually with the ruling elite and reduce dependence upon landowners and the mainland. Numerous authors have highlighted a relative lack of academic attention directly addressing the influence of political economy on achieving sustainability in post-disaster reconstruction (Klein, 2008; Hystad and Keller, 2008; Olsen, 2000; Bommer, 1985; Beirman, 2003; Faulkner, 2001; Glaesser, 2003; Ritchie, 2004). This work therefore extends existing academic debates and studies in a number of areas. In existing academic debates concerning the political economy of post-disaster reconstruction there is a trend towards 'disaster capitalism' (Klein, 2005: 3) or 'smash and grab capitalism' (Harvey, 2007: 32) and 'attempts to accumulate by dispossession' (Saltman, 2007a: 57). However, this did not occur on Phi Phi. Despite claims of a 'clean slate' being offered by the tsunami in developmental terms (Pleumarom, 2004; UNDP, 2005; Dodds, 2011; Ko, 2005; Nwankwo and Richardson, 1994; Argenti, 1976; Rice, 2005; Altman, 2005; Brix, 2007; Ghobarah et al., 2006; Dodds et al., 2010), this research provides evidence and explanation of why this did not and would never exist on Phi Phi, a finding that may be applied to other destinations in a post-disaster context. In response to Blaikie et al.'s (2004) concerns that vulnerability is often reconstructed following a disaster and may create the conditions for a future disaster, this work has extended discussions of disaster vulnerability through an adapted application of Turner et al.'s (2003) Vulnerability Framework. This meets Calgaro and Lloyd's (2008) recommendation that further longitudinal research is required in other tsunami-affected locations. This research refines their work to identify a detailed framework of vulnerability factors intertwined with factors of political economy, presenting a post-disaster situation that remains highly vulnerable and non-conducive to sustainability. This is in response to Hystad and Keller's (2008) recognition that there is a lack of long-term studies, which not only show how disaster has shifted the nature of the destination and tourism product, but also identify successful strategic processes and actions in disaster response. The strategic response has been analysed through an adapted Strategic Disaster Management Framework (Ritchie, 2004) to identify the shortcomings of the disaster response to comprehend how such a disaster has influenced tourism development and planning on the island, showing that this was a mirror opposite to how a disaster should be handled according to the literature (Ritchie, 2004; Adger et al., 2005; Miller et al., 2006; Olsen, 2000; Coppola, 2007; Faulkner, 2001; Baldini et al., 2012). The researcher draws on the notion of 'strategic drift' (Johnson, 1998: 179) and 'boiled frog syndrome' (Richardson, Nwankwo and Richardson, 1994: 10) to explain how host attitudes to tourism may increase vulnerability. Both these contributions can assist in identifying destination vulnerability and limitations in disaster response and recovery. Unlike the work of Dodds (2010) and Dodds et al. (2011), the aim was not to assess the practice and attainment of sustainability on Phi Phi; rather, it was to elaborate interpretations and conceptualisations of sustainability. An examination of development philosophy established how specific factors of political economy and relationships of a hegemonic nature influence the development trajectory of both Phi Phi and Thailand. Despite governmental rhetoric influenced by a strong 'sufficiency economy' hegemony led by King Bhumibol Adulyadej, the observations of dependency theorists provide a better fit for the experiences on Phi Phi and present significant challenges for the pursuit of sustainability. The thesis posits that an effective response to the disaster and pursuit of sustainability are undermined by the political economy of the destination.
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50

Tehrani, Shaqayeq Emambakhsh. "Effect of remote ischaemic preconditioning in patients undergoing complex PCI : the ERIC-PCI trial." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10046447/.

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Background- Coronary Heart Disease (CHD) is one of the leading causes of death and disability worldwide. Revascularisation of the coronary arteries using Percutaneous Coronary Intervention (PCI) has become the treatment of choice for most of the patients with CHD. Despite significant advances in angioplasty technique and introduction of anti-proliferative medications in drug eluting stents, myocardial injury during PCI is still significant. In this thesis we hypothesised whether Remote Ischaemic Preconditioning (RIPC) can reduce PCI-related myocardial injury. Methods- Eighty-eight patients awaiting elective complex PCI were randomly assigned in a 1:1 ratio to receive either the RIPC (intermittent arm ischaemia and reperfusion through four cycles of 5-minutes inflation and 5-minutes deflation of a blood-pressure cuff placed on the upper arm) or control (un-inflated cuff placed on upper-arm for 40 minutes) prior to PCI. The primary endpoint was reduction of the incidence and extent of PCI-related myocardial injury, assessed by serum cardiac biomarkers, 24 hours post PCI. Results- The Troponin T level at 24 hours post PCI was 48 ng/l in the control group vs 32.5 ng/l in the RIPC group, P = 0.39. There was no significant reduction in the total area under the curve (AUC) in the RIPC group, P= 0.43. Regarding the incidence of PCI-related myocardial injury, significant elevation of Troponin level post PCI (> 5 x baseline), was observed in 46.9% of patients in the control group and in 26.7 % of patients in the RIPC group, p =0.12. Conclusion- In the ERIC-PCI study, RIPC did not demonstrate a statistically significant attenuation of serum Troponin release post PCI. The results however showed a positive trend towards efficacy of RIPC in reducing PCI-related myocardial injury.
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