Relevant bibliographies by topics / PHA synthases

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'PHA synthases'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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Journal articles on the topic "PHA synthases"

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Hyakutake, Manami, Satoshi Tomizawa, Kouhei Mizuno, Hideki Abe, and Takeharu Tsuge. "Alcoholytic Cleavage of Polyhydroxyalkanoate Chains by Class IV Synthases Induced by Endogenous and Exogenous Ethanol." Applied and Environmental Microbiology 80, no. 4 (2013): 1421–29. http://dx.doi.org/10.1128/aem.03576-13.

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ABSTRACTPolyhydroxyalkanoate (PHA)-producingBacillusstrains express class IV PHA synthase, which is composed of the subunits PhaR and PhaC. RecombinantEscherichia coliexpressing PHA synthase fromBacillus cereusstrain YB-4 (PhaRCYB-4) showed an unusual reduction of the molecular weight of PHA produced during the stationary phase of growth. Nuclear magnetic resonance analysis of the low-molecular-weight PHA revealed that its carboxy end structure was capped by ethanol, suggesting that the molecular weight reduction was the result of alcoholytic cleavage of PHA chains by PhaRCYB-4induced by endog
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Alvarez-Santullano, Natalia, Pamela Villegas, Mario Sepúlveda Mardones, et al. "Genome-Wide Metabolic Reconstruction of the Synthesis of Polyhydroxyalkanoates from Sugars and Fatty Acids by Burkholderia Sensu Lato Species." Microorganisms 9, no. 6 (2021): 1290. http://dx.doi.org/10.3390/microorganisms9061290.

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Burkholderia sensu lato (s.l.) species have a versatile metabolism. The aims of this review are the genomic reconstruction of the metabolic pathways involved in the synthesis of polyhydroxyalkanoates (PHAs) by Burkholderia s.l. genera, and the characterization of the PHA synthases and the pha genes organization. The reports of the PHA synthesis from different substrates by Burkholderia s.l. strains were reviewed. Genome-guided metabolic reconstruction involving the conversion of sugars and fatty acids into PHAs by 37 Burkholderia s.l. species was performed. Sugars are metabolized via the Entne
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Chuah, Jo-Ann, Satoshi Tomizawa, Miwa Yamada, et al. "Characterization of Site-Specific Mutations in a Short-Chain-Length/Medium-Chain-Length Polyhydroxyalkanoate Synthase:In VivoandIn VitroStudies of Enzymatic Activity and Substrate Specificity." Applied and Environmental Microbiology 79, no. 12 (2013): 3813–21. http://dx.doi.org/10.1128/aem.00564-13.

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ABSTRACTSaturation point mutagenesis was carried out at position 479 in the polyhydroxyalkanoate (PHA) synthase fromChromobacteriumsp. strain USM2 (PhaCCs) with specificities for short-chain-length (SCL) [(R)-3-hydroxybutyrate (3HB) and (R)-3-hydroxyvalerate (3HV)] and medium-chain-length (MCL) [(R)-3-hydroxyhexanoate (3HHx)] monomers in an effort to enhance the specificity of the enzyme for 3HHx. A maximum 4-fold increase in 3HHx incorporation and a 1.6-fold increase in PHA biosynthesis, more than the wild-type synthase, was achieved using selected mutant synthases. These increases were subse
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Hall, Brian, Jennifer Baldwin, Ho Gun Rhie, and Douglas Dennis. "Cloning of the Nocardia corallina polyhydroxyalkanoate synthase gene and production of poly-(3-hydroxybutyrate-co-3-hydroxyhexanoate) and poly-(3-hydroxyvalerate-co-3-hydroxyheptanoate)." Canadian Journal of Microbiology 44, no. 7 (1998): 687–91. http://dx.doi.org/10.1139/w98-048.

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The polyhydroxyalkanoate (PHA) synthase gene (phaCNc) from Nocardia corallina was identified in a lambda library on a 6-kb BamHI fragment. A 2.8-kb XhoII subfragment was found to contain the ntact PHA synthase. This 2.8-kb fragment was subjected to DNA sequencing and was found to contain the coding region for the PHA synthase and a small downstream open reading frame of unknown function. On the basis of DNA sequence, phaCNc is closest in homology to the PHA synthases (phaCPaI and phaCPaII) of Pseudomonas aeruginosa (approximately 41% identity and 55% similarity). The 2.8-kb XhoII fragment cont
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Han, Jing, Jing Hou, Hailong Liu, et al. "Wide Distribution among Halophilic Archaea of a Novel Polyhydroxyalkanoate Synthase Subtype with Homology to Bacterial Type III Synthases." Applied and Environmental Microbiology 76, no. 23 (2010): 7811–19. http://dx.doi.org/10.1128/aem.01117-10.

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ABSTRACT Polyhydroxyalkanoates (PHAs) are accumulated as intracellular carbon and energy storage polymers by various bacteria and a few haloarchaea. In this study, 28 strains belonging to 15 genera in the family Halobacteriaceae were investigated with respect to their ability to synthesize PHAs and the types of their PHA synthases. Fermentation results showed that 18 strains from 12 genera could synthesize polyhydroxybutyrate (PHB) or poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). For most of these haloarchaea, selected regions of the phaE and phaC genes encoding PHA synthases (type III)
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Kolibachuk, Dana, Andrea Miller, and Douglas Dennis. "Cloning, Molecular Analysis, and Expression of the Polyhydroxyalkanoic Acid Synthase (phaC) Gene fromChromobacterium violaceum." Applied and Environmental Microbiology 65, no. 8 (1999): 3561–65. http://dx.doi.org/10.1128/aem.65.8.3561-3565.1999.

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ABSTRACT The polyhydroxyalkanoic acid synthase gene fromChromobacterium violaceum (phaC Cv) was cloned and characterized. A 6.3-kb BamHI fragment was found to contain both phaC Cv and the polyhydroxyalkanoic acid (PHA)-specific 3-ketothiolase (phaA Cv). Escherichia coli strains harboring this fragment produced significant levels of PHA synthase and 3-ketothiolase, as judged by their activities. While C. violaceum accumulated poly(3-hydroxybutyrate) or poly(3-hydroxybutyrate-co-3-hydroxyvalerate) when grown on a fatty acid carbon source, Klebsiella aerogenes andRalstonia eutropha (formerly Alca
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Tsuge, Takeharu, Manami Hyakutake, and Kouhei Mizuno. "Class IV polyhydroxyalkanoate (PHA) synthases and PHA-producing Bacillus." Applied Microbiology and Biotechnology 99, no. 15 (2015): 6231–40. http://dx.doi.org/10.1007/s00253-015-6777-9.

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Martínez-Gutiérrez, Carolina A., Hever Latisnere-Barragán, José Q. García-Maldonado, and Alejandro López-Cortés. "Screening of polyhydroxyalkanoate-producing bacteria and PhaC-encoding genes in two hypersaline microbial mats from Guerrero Negro, Baja California Sur, Mexico." PeerJ 6 (May 7, 2018): e4780. http://dx.doi.org/10.7717/peerj.4780.

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Hypersaline microbial mats develop through seasonal and diel fluctuations, as well as under several physicochemical variables. Hence, resident microorganisms commonly employ strategies such as the synthesis of polyhydroxyalkanoates (PHAs) in order to resist changing and stressful conditions. However, the knowledge of bacterial PHA production in hypersaline microbial mats has been limited to date, particularly in regard to medium-chain length PHAs (mcl-PHAs), which have biotechnological applications due to their plastic properties. The aim of this study was to obtain evidence for PHA production
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Niamsiri, Nuttawee, Soazig C. Delamarre, Young-Rok Kim, and Carl A. Batt. "Engineering of Chimeric Class II Polyhydroxyalkanoate Synthases." Applied and Environmental Microbiology 70, no. 11 (2004): 6789–99. http://dx.doi.org/10.1128/aem.70.11.6789-6799.2004.

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ABSTRACT PHA synthase is a key enzyme involved in the biosynthesis of polyhydroxyalkanoates (PHAs). Using a combinatorial genetic strategy to create unique chimeric class II PHA synthases, we have obtained a number of novel chimeras which display improved catalytic properties. To engineer the chimeric PHA synthases, we constructed a synthetic phaC gene from Pseudomonas oleovorans (phaC1 Po ) that was devoid of an internal 540-bp fragment. Randomly amplified PCR products (created with primers based on conserved phaC sequences flanking the deleted internal fragment) were generated using genomic
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Hai, Tran, Daniela Lange, Ralf Rabus, and Alexander Steinbüchel. "Polyhydroxyalkanoate (PHA) Accumulation in Sulfate-Reducing Bacteria and Identification of a Class III PHA Synthase (PhaEC) in Desulfococcus multivorans." Applied and Environmental Microbiology 70, no. 8 (2004): 4440–48. http://dx.doi.org/10.1128/aem.70.8.4440-4448.2004.

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ABSTRACT Seven strains of sulfate-reducing bacteria (SRB) were tested for the accumulation of polyhydroxyalkanoates (PHAs). During growth with benzoate Desulfonema magnum accumulated large amounts of poly(3-hydroxybutyrate) [poly(3HB)]. Desulfosarcina variabilis (during growth with benzoate), Desulfobotulus sapovorans (during growth with caproate), and Desulfobacterium autotrophicum (during growth with caproate) accumulated poly(3HB) that accounted for 20 to 43% of cell dry matter. Desulfobotulus sapovorans and Desulfobacterium autotrophicum also synthesized copolyesters consisting of 3-hydrox
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Dissertations / Theses on the topic "PHA synthases"

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Thomas, Tatiana. "Étude du potentiel biotechnologique de Halomonas sp. SF2003 : application à la production de polyhydroxyalcanoates (PHA) Complete genome sequence of the halophilic PHA-producing bacterium Halomonas sp. SF2003: insights into its biotechnological potential PHA Production and PHA Synthases of the Halophilic Bacterium Halomonas sp. SF2003." Thesis, Lorient, 2019. http://www.theses.fr/2019LORIS542.

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L’amenuisement des ressources pétrochimiques couplé à la pollution engendrée par l’exploitation des plastiques posent de nombreuses questions et conduisent à un besoin urgent de solutions alternatives. Les polyhydroxyalcanoates (PHA) sont des polymères qui ont su se démarquer et naturellement s’imposer comme matériaux de remplacement, de par leurs caractères à la fois biosourcé et biodégradable. Leur synthèse par un grand nombre d’organismes procaryotes et eucaryotes, à partir d’une large gamme de substrats carbonés, rend leur production quasi illimitée et conduit à l’obtention de polymères au
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Ravelli, Thandara Garcia. "Seleção de genes codificadores de PHA sintases para a construção de recombinantes em Burkholderia sacchari e Pseudomonas sp e avaliação da produção de polihidroxialcanoatos com diferentes composições monoméricas." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-11062015-103546/.

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Polihidroxialcanoatos (PHA) são poliésteres acumulados por diversas bactérias a partir de fontes renováveis e são termoplásticos, biodegradáveis e biocompatíveis. A variabilidade da composição monomérica de PHA determina suas propriedades mecânicas e permite seu uso em diversas aplicações. A PHA sintase é a enzima responsável pela polimerização do PHA. O objetivo deste trabalho foi à busca por genes codificadores desta enzima, construção e avaliação de recombinantes portando tais genes. Inicialmente buscaram-se novos genes de PHA sintase a partir de clones de uma biblioteca metagenômica previa
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Gajdová, Barbora. "Identifikace PHA produkujících bakterií pomocí nástrojů molekulární biologie." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316230.

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This diploma thesis deals with identification of bacteria which are capable of producing polyhydroxyalkanoates (PHAs). Work included testing variety of genera including Pseudomonas, Lactobacillus, Bifidobacterium, thermophilic cultures and samples gathered from natural sources. Bacteria were investigated by molecular technique polymerase chain reaction – PCR. An amplification of the PHA synthase gene (phaC) was analyzed. In the first reaction phaC and 16S rRNA genes were tested at the same time. 16S rRNA gene is used as control for bacterial DNA and as an identification tool for natural source
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Kubáčková, Eliška. "Molekulárně biologická charakterizace vybraných producentů PHA." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-414162.

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This diploma thesis focuses on the molecular characterization of selected PHA producers. Within this work, the PHA producing thermophilic isolates originating from the samples of activated sludge and compost were identified and characterized using molecular biological methods. By sequencing the 16S rRNA gene, the thermophilic isolates were identified and taxonomically classified into the Firmicutes bacterial phylum. In these bacterial isolates, the ability to produce PHA at the genotype level was determined by conventional PCR detection of the phaC gene encoding PHA synthase, which is a key en
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Caulkins, Juliana Carvalho de Arruda. "Identificação de genes envolvidos na síntese de polihidroxialcanoatos em Burkholderia cepacia linhagem IPT64." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-06082009-111247/.

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Os polihidroxialcanoatos (PHAs) são poliésteres acumulados por microrganismos como material de reserva. O conhecimento das vias bioquímicas e enzimas envolvidas na biossíntese e degradação dos PHAs é uma importante ferramenta para auxiliar na produção industrial. A linhagem Burkholderia cepacia IPT64 é capaz de acumular uma blenda composta de P(3HB) e P(3H4PE) a partir de sacarose. Este trabalho está focado em duas das principais enzimas envolvidas na biossíntese de PHAs: a b-cetotiolase (phaA) e a PHA sintase (phaC). A primeira está associada à especificidade pelo substrato, e a segunda é con
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Brondová, Zuzana. "Bioinformatická analýza PHA syntáz u termofilních bakterií." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-449376.

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The thesis deals with bioinformatics analysis, the aim of which was to find a suitable producer of PHA for new generation industrial biotechnologies from the collection of found thermophilic bacteria. Part of experiments was the finding of several thermophilic bacteria based on the similarity of the protein sequence of the phaC gene of the bacterium Cupriavidus necator. The next part of thesis was a literature search of the abilities of these thermophilic bacteria focused on culture conditions and the spectrum of usable substrates. Subsequently, five bacteria were selected for use in NGBI base
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Vlasáková, Terézia. "Isolace, identifikace a charakterizace extremofilů schopných produkce PHA." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2018. http://www.nusl.cz/ntk/nusl-376875.

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This diploma thesis is focused on isolation and identification of thermophilic microorganisms capable of production of polyhydroxyalkanoates (PHA) in the sample of activated sludge from wastewater treatment. 6 culture samples were isolated from activated sludge by means of cultivation technics and methods of molecular biology. They were closer specified by comparing nucleotide sequences of 16S-rRNA gene and assigned to bacterial genus Anoxybacillus. The production of PHA by this genus was not reported in literature so far. Samples were confirmed to contain phaC gene that codes the enzyme PHA-s
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Huttly, A. K. "Genes for ATP synthase subunits in pea chloroplast DNA." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356654.

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Tomlinson, Kim Louise. "Starch synthesis in leaves of pea (Pisum sativum L.)." Thesis, University of East Anglia, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297009.

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Tian, Jiamin 1974. "Mechanistic investigation of polyhydroxybutyrate (PHB) synthases and elucidation of PHB biosynthesis and degradation process in Wautersia eutropha H16." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30240.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.<br>Includes bibliographical references.<br>Polyhydroxyalkanoate (PHA) synthase from various bacterial organisms is able to catalyze the polymerization of (R)-hydroxyalkanoate-CoAs into high molecular weight PHAs under nutrient- limited conditions in the presence of a carbon source. PHA synthases are representative of enzymes involved in polymerizations in which a soluble substrate is transformed into an insoluble inclusion during the polymerization process. The initiation, elongation, and termination phases of th
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Book chapters on the topic "PHA synthases"

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Schubert, Peter, Andreas Pries, Niels Krüger, and Alexander Steinbüchel. "Molecular analysis of the Alcaligenes eutrophus PHB-biosynthetic genes: identification of the NH2-terminus of PHB synthase and identification of the transcription start site of phbC." In Novel Biodegradable Microbial Polymers. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-2129-0_42.

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Malik, Javid A., and Monika Bhadauria. "Polyhydroxyalkanoates." In Handbook of Research on Environmental and Human Health Impacts of Plastic Pollution. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-5225-9452-9.ch018.

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Human dependence on number of chemicals or chemical derivatives has increased alarmingly. Among the commodity chemicals, plastics are becoming independent for our modern lifestyle, as the usage of plastics is increasing worryingly. However, these synthetic plastics are extremely persistent in nature and accumulate in the environment, thereby leading to serious ecological problems. So, to build our economy sustainably, a need of replacement is necessary. Biomaterials in terms of bioplastics are an anticipated option, being synthesized and catabolized by different organisms with myriad biotechnological applications. Polyhydroxyalkanoates (PHAs) are among such biodegradable bioplastics, which are considered as an effective alternative for conventional plastics due to their similar mechanical properties of plastics. A range of microbes under different nutrient and environmental conditions produce PHAs significantly with the help of enzymes. PHA synthases encoded by phaC genes are the key enzymes that polymerize PHA monomers. Four major classes of PHA synthases can be distinguished based on their primary structures, as well as the number of subunits and substrate specificity. PHAs can also be produced from renewable feedstock under, unlike the petrochemically derived plastics that are produced by fractional distillation of depleting fossil fuels. Polyhydroxybutyrate (PHB) is the simplest yet best known polyester of PHAs, as the PHB derived bioplastics are heat tolerant, thus used to make heat tolerant and clear packaging film. They have several medical applications such as drug delivery, suture, scaffold and heart valves, tissue engineering, targeted drug delivery, and agricultural fields. Genetic modification (GM) may be necessary to achieve adequate yields. The selections of suitable bacterial strains, inexpensive carbon sources, efficient fermentation, and recovery processes are also some aspects important aspects taken into consideration for the commercialization of PHA. PHA producers have been reported to reside at various ecological niches with few among them also produce some byproducts like extracellular polymeric substances, rhamnolipids and biohydrogen gas. So, the metabolic engineering thereafter promises to bring a feasible solution for the production of “green plastic” in order to preserve petroleum reserves and diminish the escalating human and animal health concerns environmental implications.
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Vlachopapadopoulou, Elpis-Athina, and Myrto Bonataki. "Diagnosis of Hypoaldosteronism in Infancy." In Renin-Angiotensin Aldosterone System [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97448.

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Hypoaldosteronism is associated with either insufficient aldosterone production or lack of responsiveness to aldosterone and can be isolated or in the context of primary adrenal failure. Τhe severity of clinical manifestations is inversely correlated to age, with the neonatal period being the most vulnerable time for a patient to present with mineralocorticoid insufficiency. Salt-wasting forms of congenital adrenal hyperplasia (CAH), adrenal hypoplasia congenita (AHC), aldosterone synthase deficiency (ASD) and pseudohypoaldosteronism (PHA) are all causes of hypoaldosteronism in infancy. Affected infants present with salt wasting, failure to thrive and potentially fatal hyperkalemia and shock. Α blood sample for the essential hormonal investigations should be collected before any steroid treatment is given, in order to confirm aldosterone insufficiency and to determine the underlying cause. Renal ultrasonography and urine culture are also useful for exclusion of secondary causes of aldosterone resistance. Initial management requires treatment of electrolyte imbalances and restoration of intravascular fluid volume. In case of a salt-wasting crisis, affected infants are usually treated initially with both hydrocortisone and fludrocortisone, pending the results of investigations. Interpretation of the hormonal profile will guide further therapy and molecular analysis of candidate genes.
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Kim, M. S., J. H. Ahn, and Y. S. Yoon. "Photo-Biological Hydrogen Production by the Uptakehydrogenase and PHB Synthase Deficient Mutant of Rhodobacter Sphaeroides." In Biohydrogen III. Elsevier, 2004. http://dx.doi.org/10.1016/b978-008044356-0/50004-x.

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Frey, Perry A., and Adrian D. Hegeman. "Carbon-Carbon Condensation and Cleavage." In Enzymatic Reaction Mechanisms. Oxford University Press, 2007. http://dx.doi.org/10.1093/oso/9780195122589.003.0018.

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In chemistry, many methods are available to synthesize carbon-carbon bonds, and the reactions proceed by both polar and radical mechanisms. However, enzymatic ligation of two molecules through carbon-carbon bond formation invariably proceeds by a polar mechanism. Often, the reaction involves a carbanionic intermediate or a carbanion-equivalent species such as an enamine, but carbenium ion intermediates also participate in terpene biosynthesis. The only well-known enzymatic processes leading to carbon-carbon bonding by radical mechanisms are the adenosylcobalamin-dependent isomerization reactions discussed in chapter 7. The basic mechanisms illustrated in fig. 14-1 lead to the ligation of molecules through the synthesis of carbon-carbon bonds. Fig. 14-1A depicts the addition of a stabilized carbanion to an aldehyde or ketone to form an adduct. The carbanion can itself be derived from an aldehyde or ketone, as it is in the reactions of aldolases and transketolase. In chapter 1, we discuss the mechanisms of aldolase reactions in connection with the catalytic power of metal ions and of iminium ions formed between substrate carbonyl groups and the lysyl-ε-amino groups of enzymes. In the actions of class I aldolases, X=C in fig. 14-1A is an iminium group formed between a lysyl residue of the enzyme and an aldehyde or ketone group of a substrate. In this case, the carbanion is more accurately described as an enamine, a resonance form in which the charges are not separated. In the actions of class II aldolases, X=C in fig. 14-1A is a carbonyl group (i.e., C=O) coordinated to a divalent metal ion, usually Zn2+, which facilitates carbanion formation through enolization. In this case, the carbanion may be more accurately described as an enolate ion with the charge localized on metal-coordinated oxygen. Iminium ion formation and divalent metal ion ligation both lower the pKa value of the α-C(H) by 7-10 units, thereby facilitating enolization and carbanion formation (see chap. 1). An enolate carbanion may also be derived from a CoA-thioester such as acetyl CoA in the reaction of citrate synthase. Once the carbanion or carbanion-equivalent is formed in an active site, its addition to an aldehyde or ketone group in an adjacent cosubstrate proceeds rapidly.
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Conference papers on the topic "PHA synthases"

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Kato, K., M. Tsutsui, S. Noguchi, et al. "Spontaneous Development of Pulmonary Emphysema in Mice Lacking All Three Nitric Oxide Synthases." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6410.

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Sokolowski, Kevin M., Selvi Kunnimalaiyaan, T. Clark Gamblin, and Muthusamy Kunnimalaiyaan. "Abstract 52: Glycogen synthase kinase inhibition associated with Notch-1 reduction in cholangiocarcinoma." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-52.

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Alwarawrah, Yazan, Philip Hughes, Rachid Safi, Donald P. McDonnell, Neil L. Spector, and Timothy A. Haystead. "Abstract 2703: Overcoming Lapatinib resistance by the fatty acid synthase inhibitor HS-106." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2703.

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Kock, Anna, Karin Larsson, Raouf Joan, et al. "Abstract 1632: Microsomal prostaglandin E synthase 1: a novel therapeutic target of neuroblastoma." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1632.

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Osawa, H., T. Kiwamoto, M. T. Sherpa, et al. "Hyaluronan Synthase 2 (HAS2) Mediates Elastase-Induced Airway Inflammation and Emphysema in Mice." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4757.

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Tucker, T. A., A. Jeffers, S. Owens, W. Qin та S. Idell. "Glycogen Synthase Kinase-3β Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis". У American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2219.

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Yan, Yan, Allison Condie, and Stanton Gerson. "Abstract 3854: Inhibition of uracil DNA glycosylase (UDG) sensitizes cancer cells to thymidylate synthase inhibitors." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3854.

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Dreifus, E., R. Tian, C. Zhang, et al. "Inducible Nitric Oxide Synthase and Nitrotyrosine Are Found in the Lung of Sarcoidosis Mice Model." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3094.

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Tavora, Fabio, Tamara Lotan, Marclesson Alves та ін. "Abstract 2959: Glycogen synthase kinase 3-β expression in prostate cancer (PCa) correlates with aggressive pathological features and its blockade with 9-ING-41 inhibits viability of PCa cell lines". У Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2959.

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Trinh, Bon Q., Song Yi Ko, Dhwani Haria, Nicolas Barengo, and Honami Naora. "Abstract 4176: The homeobox gene DLX4 stimulates inducible nitric oxide synthase-mediated angiogenesis in ovarian cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4176.

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