Academic literature on the topic 'Pharmaceutical Preservatives'

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Journal articles on the topic "Pharmaceutical Preservatives"

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Boukarim, Chawki, Sarah Abou Jaoude, Rita Bahnam, Roula Barada, and Soula Kyriacos. "Preservatives in liquid pharmaceutical preparations." Drug Testing and Analysis 1, no. 3 (2009): 146–48. http://dx.doi.org/10.1002/dta.28.

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Popova, T. V., O. P. Strilets, and H. P. Kukhtenko. "Justification of preservative choice and its concentration in the composition of anti-allergic action gel." Farmatsevtychnyi zhurnal, no. 4 (July 30, 2020): 78–87. http://dx.doi.org/10.32352/0367-3057.4.20.08.

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Microbiological stability of medicines is an integral part of their quality, therefore, at the stage of pharmaceutical development, the issues of ensuring microbiological purity should be considered. To this end, various chemicals are added to the composition of semisolid medicines that actively inhibit the growth of microorganisms that enter the pharmaceutical system during production and reuse. Insufficient amount of a preservative can lead to the adaptation of microorganisms, and excess- to increase the toxicity of the drug. In the development of the composition of the anti-allergic action
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Storz, Michael P., and Lea Holsten. "Empirical Analysis Revealing Privileged Chemical Space of Cosmetic Preservatives." Cosmetics 8, no. 3 (2021): 80. http://dx.doi.org/10.3390/cosmetics8030080.

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Most cosmetic products require preservation to prevent microbial contamination and to ensure consumer safety. Due to regulatory restrictions and rejection by consumers, preservative options have become limited and the development of novel solutions is needed. This search can be guided by knowledge about favorable chemical space for cosmetic preservatives. Therefore, we used preservatives allowed in the EU as training set and calculated various molecular properties. Empirical analysis revealed two separated areas of privileged chemical space with the net charge as distinctive property. The firs
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Alekseev, I. B., A. V. Volkova, and L. I. Alekseeva. "Characteristics of glaucoma therapy with prostaglandin analogues nowadays." Russian Journal of Clinical Ophthalmology 22, no. 3 (2022): 175–80. http://dx.doi.org/10.32364/2311-7729-2022-22-3-175-180.

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Ocular hypotensive prostaglandin analogues (PGAs) are prodrugs that penetrate the cornea and become biologically active after hydrolysis by corneal esterase. They reduce intracranial pressure by increasing the uveoscleral outflow of aqueous humour and decreasing the outflow resistance. PGAs remain relevant as the first-line therapy drugs for patients with newly diagnosed glaucoma. The obvious exposure drawbacks of eye drops with preservatives have become prerequisites for the use of preservative-free medicines. Currently, it is recommended to use eye drops with preservatives less commonly, in
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Myrhorod, V. S., O. H. Bashura, O. P. Strilets, S. H. Bobro, and L. S. Strelnykov. "Study of the efficacy of antimicrobial preservatives in justifying the composition of a dermatological gel with a phytocomplex." Current issues in pharmacy and medicine: science and practice 14, no. 3 (2021): 306–13. http://dx.doi.org/10.14739/2409-2932.2021.3.239291.

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The microbiological stability of medicinal products always requires close attention during the pharmaceutical development phase, as microbial contamination can pose a threat to both the health of the patient and the stability of the medicinal product. The level of microbial contamination can be controlled by monitoring the quality of raw materials, compliance with appropriate sanitation of production facilities and equipment, the use of scientifically justified preservatives in the drug. The aim of the work is to substantiate the use of a preservative and its concentration in the composition o
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&NA;. "Two common pharmaceutical preservatives have shown synergistic ciliotoxicity." Reactions Weekly &NA;, no. 454 (1993): 4. http://dx.doi.org/10.2165/00128415-199304540-00006.

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Lourenço, Felipe Rebello, Fabiane Lacerda Francisco, Márcia Regina Spuri Ferreira, Terezinha De Jesus Andreoli, Raimar Löbenberg, and Nádia Bou-Chacra. "Design Space Approach for Preservative System Optimization of an Anti-Aging Eye Fluid Emulsion." Journal of Pharmacy & Pharmaceutical Sciences 18, no. 3 (2015): 551. http://dx.doi.org/10.18433/j3j600.

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The use of preservatives must be optimized in order to ensure the efficacy of an antimicrobial system as well as the product safety. Despite the wide variety of preservatives, the synergistic or antagonistic effects of their combinations are not well established and it is still an issue in the development of pharmaceutical and cosmetic products. The purpose of this paper was to establish a space design using a simplex-centroid approach to achieve the lowest effective concentration of 3 preservatives (methylparaben, propylparaben, and imidazolidinyl urea) and EDTA for an emulsion cosmetic produ
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Ullah, Hammad, Yaseen Hussain, Cristina Santarcangelo, et al. "Natural Polyphenols for the Preservation of Meat and Dairy Products." Molecules 27, no. 6 (2022): 1906. http://dx.doi.org/10.3390/molecules27061906.

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Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, salting, or fermentation. Water activity, temperature, redox potential, preservatives, and competitive microorganisms are the most important approaches used in the preservation of food products. Preservative agents are generally classified into antimicrobial, antioxidant, and anti-browning agents. On the other hand, artificial preservatives (sorbate, sulfite,
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Wang, Ya Mei, Xi Ming Wang, and Jun Liang Liu. "Study on Antibacterial Mechanism of CuAz Preservative on Wood White Rot Fungi." Applied Mechanics and Materials 195-196 (August 2012): 330–33. http://dx.doi.org/10.4028/www.scientific.net/amm.195-196.330.

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CuAz preservative is a new kind of wood preservative product with high efficient and low toxicity. In order to study antibacterial mechanism of CuAz preservative on white rot fungi, the form toxicological action of preservatives on the wood decay fungi and effect on fungi protein are examined in this paper. The results show that binding forms of toxicological role and protein electrophoresis has changed, we can analyze that the inhibitory role of the pharmacy which is likely to affect the pharmaceutical fungi related to the regulation of DNA synthesis gene expression. Thus prevented the protei
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Attia, Gouda H., Diaa A. Marrez, Mona A. Mohammed, Hassan A. Albarqi, Ammar M. Ibrahim, and Mohamed A. El Raey. "Synergistic Effect of Mandarin Peels and Hesperidin with Sodium Nitrite against Some Food Pathogen Microbes." Molecules 26, no. 11 (2021): 3186. http://dx.doi.org/10.3390/molecules26113186.

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Food preservatives such as NaNO2, which are widely used in human food products, undoubtedly affect, to some extent, human organs and health. For this reason, there is a need to reduce the hazards of these chemical preservatives, by replacing them with safe natural bio-preservatives, or adding them to synthetic ones, which provides synergistic and additive effects. The Citrus genus provides a rich source of such bio-preservatives, in addition to the availability of the genus and the low price of citrus fruit crops. In this study, we identify the most abundant flavonoids in citrus fruits (hesper
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Dissertations / Theses on the topic "Pharmaceutical Preservatives"

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Ingram, Paul Richard. "The mechanism of action of the opthalmic preservative Purite™ and a comparison to other preservatives." Thesis, University of Strathclyde, 2002. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21189.

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The use of preservatives in ophthalmic pharmaceuticals is mandatory to inhibit the growth of micro-organisms whilst on the shelf and during use. Traditional preservatives used in this application, over the long-term, are reported to cause serious patient reactions limiting their use. The novel oxy-chloro compound Purite™; is a newer generation ocular preservative that overcomes some of the patient related problems. Although the major constituent of Purite™; is sodium chlorite, very little is known about the exact mechanism for the activity of chlorite solutions as preservatives and the reasons
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Batts, A. H. "A study of the ciliotoxicity of some pharmaceutical preservatives." Thesis, University of Brighton, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234042.

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Roy, Shouvik. "Mechanistic studies of physico-chemical stability of model therapeutic proteins using pharmaceutically relevant factors /." Connect to full text via ProQuest. IP filtered, 2006.

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Thesis (Ph.D. in Pharmaceutical Sciences) -- University of Colorado at Denver and Health Sciences Center, 2006.<br>Typescript. Includes bibliographical references (leaves 161-173). Free to UCDHSC affiliates. Online version available via ProQuest Digital Dissertations;
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Gilliland, David. "Kinetic modelling of preservative systems." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334622.

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Sheppard, Fiona Cathleen. "The application of rapid microbiological methods to preservative efficacy testing of pharmaceuticals." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243903.

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Pacheco, Ana Rita Borba. "Parabenos nas formulações cosméticas : sim ou não?" Master's thesis, 2018. http://hdl.handle.net/10437/9064.

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Orientação: Catarina Fialho Rosado ; co-orientação: Joana Filipa Portugal Faria da Mota<br>Os parabenos são amplamente utilizados como conservantes em muitos alimentos, cosméticos e, produtos de higiene pessoal e medicamentos, devido ao seu perfil característico de baixa toxicidade e a uma longa história de uso seguro. Os parabenos são ésteres de alquil do ácido p-hidroxibenzóico e tipicamente incluem metilparabeno, etilparabeno, propilparabeno, butilparabeno, isobutilparabeno, isopropilparabeno e benzilparabeno. Estes compostos são conhecidos por terem um valor nulo ou fraca actividade estro
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Books on the topic "Pharmaceutical Preservatives"

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G, Board R., Allwood M. C, and Banks J. G, eds. Preservatives in the food, pharmaceutical and environmental industries. Blackwell Scientific Publications, 1987.

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Batts, Alison Heather. A study of the ciliotoxicity of some pharmaceutical preservatives. Brighton Polytechnic Department of Pharmacy, 1989.

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3

-Y, Maillard J., and Sattar Syed, eds. Principles and practice of disinfection, preservation, and sterilization. 5th ed. John Wiley & Sons, 2012.

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Russell, A. D., Peter A. Lambert, Adam P. Fraise, and J. Y. Maillard. Russell, Hugo & Ayliffe's principles and practice of disinfection, preservation and sterilization. 4th ed. Blackwell Pub., 2004.

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Kirby, David, and David Kirby. Evidence of harm: Mercury in vaccines and the autism epidemic : a medical controversy. St. Martin's Press, 2005.

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Board, R. G., and M. C. Allwood. Preservatives in Food, Pharmaceutical and Environmental Industries (Technical Series (Society for Applied Bacteriology)). Blackwell Science Inc, 1987.

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Fraise, Adam P., Syed Sattar, and Jean-Yves Maillard. Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization. Wiley & Sons, Incorporated, John, 2012.

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(Contributor), Gaj Ayliff, Jeremy Bagg (Contributor), Rosamund Baird (Contributor), et al., eds. Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization. 4th ed. Blackwell Publishing Limited, 2004.

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(Editor), Donald S. Orth, Jon J. Kabara (Editor), Stephen P. Denyer (Editor), and S. K. Tan (Editor), eds. Cosmetic and Drug Microbiology (Cosmetic Science and Technology Series). Informa Healthcare, 2006.

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Lambert, Peter A., Adam P. Fraise, and Jean-Yves Maillard. Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization. Wiley & Sons, Incorporated, John, 2008.

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Book chapters on the topic "Pharmaceutical Preservatives"

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Nahler, Gerhard. "preservatives." In Dictionary of Pharmaceutical Medicine. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_1110.

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Sandle, Tim. "Antibiotics and preservatives." In Pharmaceutical Microbiology. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-08-100022-9.00014-1.

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"Antimicrobial Effectiveness Test and Preservatives in Pharmaceutical Products." In Microbial Contamination Control in the Pharmaceutical Industry. CRC Press, 2004. http://dx.doi.org/10.1201/9780203026267-13.

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Nazir, Ishrat, and Sajad Ahmad Gangoo. "Pharmaceutical and Therapeutic Potentials of Essential Oils." In Essential Oils - Advances in Extractions and Biological Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102037.

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It is a common perspective that medicinal plants have played and continue to perform an undeniably major role in the lives of people worldwide. Essential oils are the key constituents of medicinal herbs and their biological activities have been discovered since ancient times and are enormously utilised in multiple industries. The essential oils possess important biological properties like antibacterial, antioxidant, antiviral, insecticidal, etc. Because of these unique features they are more acceptable and are utilised in various fields throughout the world. In the cosmetics industry they play an important role in the development of perfumes while in the food industry they have been used as food preservatives. Essential oil components are interestingly utilised for pharmaceutical applications. The most investigated properties are antioxidant, anti-inflammatory, antimicrobial, wound-healing, anxiolytic activities etc. The current thrust area is evaluation for aromatherapy and anti-cancer, as it is noted that essential oils reported in plants may prevent, inhibit, or even reverse formation of cancerous cells. The aim of this chapter is to provide a concise and comprehensive overview on the therapeutic and pharmaceutical potential of essential oils in the current scenario.
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Patel, Anuradha, Sanjesh Tiwari, Neeraj Pandey, Divya Gupta, and Sheo Mohan Prasad. "Role of Spices Beyond a Flavouring Agent." In Ethnopharmacological Investigation of Indian Spices. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2524-1.ch002.

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Plants, principally spices and herbs, have been given much more attention because they are considered important for flavoring and coloring foods and their use as condiments. Herbs and spices have been used for generations by humans as food and also to treat ailments since they are full of medicinal and antioxidant properties and contain bioactive compounds like tannins, alkaloids, phenolics, flavonoids, polyphenols, and vitamins, which help in healing diseases. Spices and herbs contain biomolecules that play a crucial role in healthcare and fitness levels. Spices and herbs have been considered as esoteric food adjuncts as they play numerous roles like being coloring agents, flavoring agents, preservatives, food additives, and having uses in the medicinal and pharmaceutical industries.
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Patel, Anuradha, Sanjesh Tiwari, Neeraj Pandey, Divya Gupta, and Sheo Mohan Prasad. "Role of Spices Beyond a Flavouring Agent." In Research Anthology on Recent Advancements in Ethnopharmacology and Nutraceuticals. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-3546-5.ch032.

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Plants, principally spices and herbs, have been given much more attention because they are considered important for flavoring and coloring foods and their use as condiments. Herbs and spices have been used for generations by humans as food and also to treat ailments since they are full of medicinal and antioxidant properties and contain bioactive compounds like tannins, alkaloids, phenolics, flavonoids, polyphenols, and vitamins, which help in healing diseases. Spices and herbs contain biomolecules that play a crucial role in healthcare and fitness levels. Spices and herbs have been considered as esoteric food adjuncts as they play numerous roles like being coloring agents, flavoring agents, preservatives, food additives, and having uses in the medicinal and pharmaceutical industries.
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Hodges, Norman, and Geoffrey Hanlon. "Antimicrobial Preservative Efficacy Testing." In Pharmaceutical Science Series. CRC Press, 2000. http://dx.doi.org/10.1201/9780203305195.ch10.

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Baird, Rosamund M. "Preservative Efficacy Testing in the Pharmaceutical Industries." In Microbiological Quality Assurance. CRC Press, 2018. http://dx.doi.org/10.1201/9781351074551-11.

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Denyer, Stephen. "Antimicrobial Preservatives and Their Properties." In Guide to Microbiological Control in Pharmaceuticals and Medical Devices, Second Edition. CRC Press, 2006. http://dx.doi.org/10.1201/9781420021622.ch14.

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Harman, Robin, and R. Keith Greenwood. "Preservatives, Antimicrobial Agents, and Antioxidants." In Guide to Microbiological Control in Pharmaceuticals and Medical Devices, Second Edition. CRC Press, 2006. http://dx.doi.org/10.1201/9781420021622.ch19.

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