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Journal articles on the topic 'Pharmaceutical properties'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Alkhatib, Ahed J., Sani S. Bala, S. S. Bashir, and Abdulhadi M. "CHEMICAL AND PHARMACEUTICAL PROPERTIES OF PEFLOXACIN: A REVIEW." Indian Research Journal of Pharmacy and Science 5, no. 2 (2018): 1427–31. http://dx.doi.org/10.21276/irjps.2018.5.2.4.

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2

Tupe, Suraj Ankush, Shital Prabhakar Khandagale, and Amrapali B. Jadhav. "Pharmaceutical Cocrystals: An Emerging Approach to Modulate Physicochemical Properties of Active Pharmaceutical Ingredients." Journal of Drug Delivery and Therapeutics 13, no. 4 (2023): 101–12. http://dx.doi.org/10.22270/jddt.v13i4.6016.

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Most of the Active Pharmaceutical Ingredients (APIs) are typically formulated and administered to patients in oral solid dosage forms due to ease of administration, patient compliance and cost effectiveness. Poor water solubility, low permeability and low bioavailability of APIs are major hurdles in development of oral solid dosage forms. In recent years, cocrystal development has evolved as a feasible approach for enhancing the solubility and bioavailability of poorly soluble drugs. Crystal engineering strategies have been asserted to enhance the likelihood of discovering new solid forms of a

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3

Savale, Aishwarya, Rajendra Mogal, Swati Talele, Sumit Deore, and Laxmikant Borse. "Pharmaceutical Cocrystals: A Novel Systematic Approach for the Administration of Existing Drugs in New Crystalline Form." Biosciences Biotechnology Research Asia 20, no. 4 (2023): 1195–210. http://dx.doi.org/10.13005/bbra/3168.

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ABSTRACT: Poor physicochemical properties like solubility, dissolution profile, stability, etc. of drugs remain as an obstacle to formulation development. In the last two decades, pharmaceutical cocrystal gaining lots of interest from researchers as these physicochemical, mechanical, and pharmacokinetic properties can be altered without compromising the therapeutic effect. The multi-component systems wherein one component is essentially the Active Pharmaceutical Ingredient and another may be either one more drug or coformer are termed as pharmaceutical cocrystal. Cocrystal is a novel, promisin

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4

Sarkar, Manoleena, Rajnandan Borah, Rajat Das, Pallab Ghosh, Chandrika Sharma, and Jyochhana Priya Mohanty. "Pharmaceutical Co-crystals: A Review on its Physico-chemical Properties and Role in the Management of Cancer." Journal of Pharmaceutical Research 23, no. 1 (2024): 1–6. http://dx.doi.org/10.18579/jopcr/v23.1.74.

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Academic and industry researchers are becoming more interested in pharmaceutical cocrystals as they emerge as a new class of solid pharmaceuticals with enhanced physico-chemical features. Pharmaceutical co-crystal formation is a simple method for significantly altering a therapeutic substance's solid-state characteristics namely its solubility and consequently bioavailability. A drug's physico-chemical properties can be adjusted by a cocrystal between an active pharmaceutical ingredient (API) and co-former without altering the drug's molecular structure. Numerous types of co-crystals, nano co-

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5

Ghermani, N. E., N. El Hassan, J. M. Gillet, N. Guiblin, and A. Spasojevic-de Biré. "Electron properties of pharmaceutical molecules." Acta Crystallographica Section A Foundations of Crystallography 68, a1 (2012): s54. http://dx.doi.org/10.1107/s0108767312098960.

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6

Šibanc, Rok, Teja Kitak, Biljana Govedarica, Stanko Srčič, and Rok Dreu. "Physical properties of pharmaceutical pellets." Chemical Engineering Science 86 (February 2013): 50–60. http://dx.doi.org/10.1016/j.ces.2012.04.037.

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7

Turgunov, Davron Elibekovich, Zoyir Akhmadovich Eshankulov, and Bahodir Dustmurodov. "CAPPARIS SPINOSA L.PLANTS PHARMACEUTICAL PROPERTIES." GOLDEN BRAIN 1, no. 8 (2023): 44–46. https://doi.org/10.5281/zenodo.7772389.

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8

Mamatkulov, Z.U. Kayumova G.G. "PHARMACEUTICAL PROPERTIES OF CALENDULA OFFICINALIS." DEVELOPMENT AND INNOVATIONS IN SCIENCE 2, no. 9 (2023): 35–36. https://doi.org/10.5281/zenodo.8405011.

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Calendula officinalis (Calendula), Asteraceae to his family, usually known as English Marigold or Pot Marigold fragrant grass is traditional _ medicine in the system for ulcers, stomach ulcers, herpes, scars, skin injury, cold and the cold in treatment is used blood cleaning. Its different biological activities because of analgesic, diabetes, wound and inflammation against diseases treatment is used. It is also gastrointestinal, gynaecological, and eye diseases of skin damage and some burns in cases used.

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9

Mamatkulov, Z.U. Kayumova G.G. "PHARMACEUTICAL PROPERTIES OF FLORES TANACETI." MODELS AND METHODS IN MODERN SCIENCE 2, no. 10 (2023): 43–44. https://doi.org/10.5281/zenodo.8405024.

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Dandelion (Tanacetum vulgare L., syn. Chrysanthemum vulgare L.) is an intensely aromatic plant belonging to the Asteraceae family, found in Europe and Asia, growing along roadsides, hedgerows and deserts. Medicines contain 0.1-1.9% essential oil, phenolic acids, flavonoids (derivatives of quercetin and luteolin), bitter and mineral compounds from flower baskets of tansy (Tanaceti flos) and tansy herb (Tanaceti herba). is prepared. Tansy oil has a variable composition; its main components are beta-thujone, isomers, terpenes, camphene, beta-pinene, etc.

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10

Ingle, Rahul G. Ingle, Samiksha S. Khobragade G., and Samiksha S. Khobragade. "Titanium Dioxide (TiO2): A Versatile Excipient in Pharmaceuticals." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1811–13. http://dx.doi.org/10.25258/ijddt.14.3.78.

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Titanium dioxide (TiO2) is a commonly used excipient in pharmaceutical formulations, offering several benefits to pharmaceutical products. As a highly insoluble and thermally stable oxide, TiO2 is utilized as an opacifying agent and suspending agent to improve the appearance, stability, and bioavailability of pharmaceutical products. Its high refractive index and high surface area make it an excellent adsorbent and filler material, while its non-toxic and odorless nature ensures its safe use in pharmaceutical applications. Here, the authors deliberate the properties and major applications of T

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11

Raheem Thayyil, Abdul, Thimmasetty Juturu, Shashank Nayak, and Shwetha Kamath. "Pharmaceutical Co-Crystallization: Regulatory Aspects, Design, Characterization, and Applications." Advanced Pharmaceutical Bulletin 10, no. 2 (2020): 203–12. http://dx.doi.org/10.34172/apb.2020.024.

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Pharmaceutical co-crystals are novel class of pharmaceutical substances, which possess an apparent probability of advancement of polished physical properties offering stable and patentable solid forms. These multi-component crystalline forms influence pertinent physicochemical parameters like solubility, dissolution rate, chemical stability, physical stability, etc. which in turn result in the materials with superior properties to those of the free drug. Co-crystallization is a process by which the molecular interactions can be altered to optimize the drug properties. Co-crystals comprise a mu

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12

Aslanian, M. A., L.O Bobrytska, and T.P. Osolodchenko. "ANTIBACTERIAL PROPERTIES OF PHARMACEUTICAL COMPOSITION OF HEPATOPROTECTORS." Annals of Mechnikov Institute, no. 4 (December 2, 2016): 102–6. https://doi.org/10.5281/zenodo.192328.

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Pathology problemof hepatobiliary system (HBS) of contagious origin becomes relevant with the increase of disturbance and complications of lipid metabolism and bile pigments among young people. Leading role in prophylaxis and treatment in the context of this pathology belongs to antibacterialc hemotherapeutic agents. However, along with antimicrobial activity, numerous side effects can be observed during treatment with antibacterial agents. According to the recent study on hepatobiliary system (HBS), therapeutic effect can be seen only while using herbal medicine with choleretic action as well

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13

Eddin Mohamed, Ammar S., and Ghazwan H. AbdulWahhab. "Preparation and Characterization of Nano Graphene Oxide-decorated ampicillin and pefloxacin." E3S Web of Conferences 621 (2025): 02008. https://doi.org/10.1051/e3sconf/202562102008.

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In this research study, a novel and innovative approach was employed to synthesize a graphene oxide material. The synthesis process involved the reaction of graphite with sulfuric acid, carried out under controlled conditions in the presence of strong reducing and oxidizing agents. This carefully designed process ensured the formation of the desired graphene oxide. The resulting graphene oxide, functionally enriched through the Hummer oxidation, was employed as a crucial component in the preparation of some nano pharmaceutical compounds. Specifically, the researchers utilized the graphene oxid

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14

Baxtigul, Abdurahmonova, and Boboyorov Sirojiddin. "MEDICINAL PROPERTIES OF KAVUL PLANT." American Journal Of Agriculture And Horticulture Innovations 02, no. 12 (2022): 36–38. http://dx.doi.org/10.37547/ajahi/volume02issue12-07.

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Koval is healing from root to leaf. Therefore, it is highly valued as a valuable raw material in the pharmaceutical industry. The article provides information about the healing properties of this plant, which diseases are useful in our medicine.

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15

Okoduwa, I. O., B. J. Enagbonma, and E. E. Imade. "Effects of Pharmaceutical Effluents on Soil Microbiome and Physicochemical Parameters." Journal of Applied Sciences and Environmental Management 26, no. 8 (2022): 1363–67. http://dx.doi.org/10.4314/jasem.v26i8.7.

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Soil contamination from pharmaceuticals is an evolving issue, consequently measurable data on their microbial effects are deficient. Thus, this study investigated the effects of pharmaceutical effluents on soil microbiome and the physicochemical parameters of soil samples obtained from Ugbowo, Benin City, Nigeria using standard procedures. The experiment which lasted for four weeks consists of four treatments of soil samples with pharmaceutical effluents of different percentages and one soil sample without pharmaceutical effluents (control). These include: soil treated with 250 ml of pharmaceu

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16

de Ridder, D. J., A. R. D. Verliefde, S. G. J. Heijman, et al. "Influence of natural organic matter on equilibrium adsorption of neutral and charged pharmaceuticals onto activated carbon." Water Science and Technology 63, no. 3 (2011): 416–23. http://dx.doi.org/10.2166/wst.2011.237.

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Natural organic matter (NOM) can influence pharmaceutical adsorption onto granular activated carbon (GAC) by direct adsorption competition and pore blocking. However, in the literature there is limited information on which of these mechanisms is more important and how this is related to NOM and pharmaceutical properties. Adsorption batch experiments were carried out in ultrapure, waste- and surface water and fresh and NOM preloaded GAC was used. Twenty-one pharmaceuticals were selected with varying hydrophobicity and with neutral, negative or positive charge. The influence of NOM competition a

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17

Carter, Laura J., John L. Wilkinson, and Alistair B. A. Boxall. "Evaluation of Existing Models to Estimate Sorption Coefficients for Ionisable Pharmaceuticals in Soils and Sludge." Toxics 8, no. 1 (2020): 13. http://dx.doi.org/10.3390/toxics8010013.

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In order to assess the environmental risk of a pharmaceutical, information is needed on the sorption of the compound to solids. Here we use a high-quality database of measured sorption coefficients, all determined following internationally recognised protocols, to evaluate models that have been proposed for estimating sorption of pharmaceuticals from chemical structure, some of which are already being used for environmental risk assessment and prioritization purposes. Our analyses demonstrate that octanol-water partition coefficient (Kow) alone is not an effective predictor of ionisable pharma

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18

Lomartire, Silvia, and Ana M. M. Gonçalves. "Algal Phycocolloids: Bioactivities and Pharmaceutical Applications." Marine Drugs 21, no. 7 (2023): 384. http://dx.doi.org/10.3390/md21070384.

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Seaweeds are abundant sources of diverse bioactive compounds with various properties and mechanisms of action. These compounds offer protective effects, high nutritional value, and numerous health benefits. Seaweeds are versatile natural sources of metabolites applicable in the production of healthy food, pharmaceuticals, cosmetics, and fertilizers. Their biological compounds make them promising sources for biotechnological applications. In nature, hydrocolloids are substances which form a gel in the presence of water. They are employed as gelling agents in food, coatings and dressings in phar

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19

Hansen, Daiane, Mitsue Haraguchi, and Antonio Alonso. "Pharmaceutical properties of 'sucupira' (Pterodon spp.)." Brazilian Journal of Pharmaceutical Sciences 46, no. 4 (2010): 607–16. http://dx.doi.org/10.1590/s1984-82502010000400002.

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The plant of the genus Pterodon (Fabaceae, Leguminosae), commonly known as 'sucupira' or 'faveira', are disseminated throughout the central region of Brazil and has frequently been used in popular medicine for its anti-rheumatic, analgesic, and anti-inflammatory properties. In recent years, interest in these plants has increased considerably. The biological effects of different phytoextracts and pure metabolites have been investigated in several experimental models in vivo and in vitro. The literature describes flavonoids, triterpene and steroids, while one paper presented studies with protein

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20

Sá, Rita de Cássia da Silveira e., Reinaldo Nóbrega de Almeida, and Jnanabrata Bhattacharyya. "Pharmaceutical properties and toxicology ofDioclea grandiflora." Pharmaceutical Biology 51, no. 5 (2013): 659–67. http://dx.doi.org/10.3109/13880209.2012.755208.

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21

Altomare, Angela. "Solid-state properties of pharmaceutical materials." Crystallography Reviews 26, no. 2 (2019): 115–16. http://dx.doi.org/10.1080/0889311x.2019.1698555.

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22

Schultheiss, Nate, and Ann Newman. "Pharmaceutical Cocrystals and Their Physicochemical Properties." Crystal Growth & Design 9, no. 6 (2009): 2950–67. http://dx.doi.org/10.1021/cg900129f.

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23

Rijnierse, Anneke, Prescilla V. Jeurink, Betty C. A. M. van Esch, Johan Garssen, and Léon M. J. Knippels. "Food-derived oligosaccharides exhibit pharmaceutical properties." European Journal of Pharmacology 668 (September 2011): S117—S123. http://dx.doi.org/10.1016/j.ejphar.2011.07.009.

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24

Krok, Alexander, Nuno Vitorino, Jianyi Zhang, Jorge Ribeiro Frade, and Chuan-Yu Wu. "Thermal properties of compacted pharmaceutical excipients." International Journal of Pharmaceutics 534, no. 1-2 (2017): 119–27. http://dx.doi.org/10.1016/j.ijpharm.2017.10.018.

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25

Verevkin*, Sergey P., Kseniya V. Zherikova, Sergey V. Vostrikov, and Irina I. Kaygorodova. "Beware with the Quality of Thermodynamic Data Diagnostic Check of Phase Transitions Energetics of Active Pharmaceutical Ingredients." Journal of Biomedical Research & Environmental Sciences 5, no. 9 (2024): 1187–99. http://dx.doi.org/10.37871/jbres2007.

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Thermodynamics is crucial for optimizing drug synthesis, developing pharmaceutical formulations and ensuring their stability, effectiveness and safety. The thermochemical properties of active pharmaceutical ingredients with the common biphenyl motif (RS-Flurbiprofen, Diflunisal, Fenbufen and Biprofen) available in the literature were collected, combined with our own complementary experimental results and evaluated. The vapour pressures temperature dependence of RS-Flurbiprofen was measured using the Knudsen effusion method, and the enthalpy of sublimation was obtained from this measurement. Th

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26

Liu, Chuanxin, Bangchao Liang, Yangguang Zhao, and Xiaoxiao Han. "Effects of Hot-Melt-Extrusion process parameters on the Feedability of Fused Deposition Modeling filaments." Journal of Physics: Conference Series 2355, no. 1 (2022): 012017. http://dx.doi.org/10.1088/1742-6596/2355/1/012017.

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Abstract Fused deposition modelling (FDM) has shown its advantages in the field of personalized oral medicine due to its low cost, simplicity and flexible manufacturing for on- demand doses. However, most pharmaceutical-grade polymers that can be hot-melt extruded do not have the mechanical properties for high-quality FDM feedstock, and it is considered a barrier to further development of FDM pharmaceutical applications. In this paper, the impacts of Hot- Melt Extrusion (HME) process parameters on the mechanical properties of FDM filaments is explored for the brittle polymer polyvinylpyrrolido

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27

Singh, Maan, Harsh Barua, Vaskuri G. S. Sainaga Jyothi, et al. "Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems." Pharmaceutics 15, no. 4 (2023): 1161. http://dx.doi.org/10.3390/pharmaceutics15041161.

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Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and stability present a significant challenge during their processing into final dosage forms. Cocrystallization of such APIs with suitable coformers is an efficient approach to mitigate the solubility and stability concerns. A considerable number of cocrystal-based products are currently being marketed and show an upward trend. However, to improve the API properties by cocrystallization, coformer selection plays a paramount role. Selection of suitable coformers not only improves the drug’s physicochemical prop

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28

Syroeshkin, A. V., T. E. Elizarova, T. V. Pleteneva, et al. "The Influence of Deuterium on the Properties of Pharmaceutical Substances (Review)." Drug development & registration 9, no. 2 (2020): 24–32. http://dx.doi.org/10.33380/2305-2066-2020-9-2-24-32.

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Introduction. The study discusses the hydrogen isotope 2 H effect on the biological activity of pharmaceutical substances.Text. Two aspects of the deuterium effect on the properties of active pharmaceutical ingredients and excipients are considered. The first one involves the use of deuterated substances, new compounds or substituted counterparts. Replacing protium with deuterium is used to reduce the rate of biotransformation. The kinetic isotope effect (KIE), expressed in a decrease in the rate of biotransformation as a result of deuteration, allows us to predict the rapid development of new

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29

Szarka, Agneša, Lucia Vnuková, Zuzana Keršňáková, Nicolette Viktoryová, and Svetlana Hrouzková. "Contamination with Pharmaceuticals in Aquatic Environment: Focus on Analytical Methodologies." Applied Sciences 14, no. 19 (2024): 8645. http://dx.doi.org/10.3390/app14198645.

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The growing prevalence of pharmaceutical compounds in the environment raises significant concerns due to their potential impacts on ecological and human health. This present manuscript focuses on the methods used to extract and determine these pharmaceuticals in water samples. It provides a comprehensive analysis of the extraction techniques and analytical approaches employed for the identification and quantification of pharmaceuticals in environmental water. Due to their chemical properties and widespread use, pharmaceuticals persist in the environment and contaminate water bodies, soil, and

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30

Tushar, B. Aher Prof. Poonam P. Khade Dr. Megha T. Salve. "Pharmaceutical Formulation and Development: A Comprehensive Review." International Journal in Pharmaceutical Sciences 1, no. 1 (2023): 346–55. https://doi.org/10.5281/zenodo.10144551.

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The abstract discusses the significance of preformulation studies, which analyze the physicochemical characteristics of potential new drug candidates and their impact on drug performance and dosage form development. These studies provide essential information for designing formulations and may indicate the need for molecular modifications. Before creating pharmaceutical formulations, it's crucial to consider the inherent chemical and physical properties of each drug, which serve as the foundation for combining them with other ingredients in dosage form production. The primary objective of pref

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31

Carlton, R. A. "Microscopy in Pharmaceutical Development." Microscopy and Microanalysis 4, S2 (1998): 478–79. http://dx.doi.org/10.1017/s1431927600022510.

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Many different microscopic techniques are utilized in the development of new pharmaceuticals. For that reason, pharmaceutical companies have supported microscopy and microscopists even in the face of retrenchments in many other industries. Microscopy has the following three major uses in pharmaceutical development: 1) solid-state characterization of drug substance; 2) particle size analysis; 3) contaminant identification. Microscopy is also an important component of the study of the biological activity of drugs but that subject will not be discussed here.The analysis of the solid-state propert

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32

Khaligh, Nader G., Hanna Abbo, Salam J. J. Titinchi, and Mohd R. Johan. "An Overview of Recent Advances in Biological and Pharmaceutical Developments of Fluoro-containing Drugs." Current Organic Chemistry 23, no. 26 (2020): 2916–44. http://dx.doi.org/10.2174/1385272824666191213123930.

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: This review article provides a brief assessment of the biological and pharmaceutical developments of fluorinated drugs. It also discusses possible impacts on the further development of new fluoro-containing pharmaceuticals. Structural aspects of new drug-candidates currently under development and their biological properties, therapeutic potential and syntheses are critically evaluated

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33

Kondratiuk, A. S. "COMPREHENSIVE REVIEW OF OINTMENT BASES: TYPES, PROPERTIES, AND APPLICATIONS." Biotechnologia Acta 18, no. 1 (2025): 5–15. https://doi.org/10.15407/biotech18.01.005.

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Aim. This article aims to comprehensively review and analyze various types of ointment bases, examining their physicochemical properties, advantages, and disadvantages. This review also seeks to explore the potential use of specific excipients in developing ointment bases with enhanced therapeutic properties and increased bioavailability of active pharmaceutical ingredients. Methods. A broad search and study of existing literature on ointment bases, focusing on their classifications, properties, and applications. A comparative analysis of the two main classifications of ointment bases based on

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34

Marcato, Priscyla D., and Nelson Durán. "New Aspects of Nanopharmaceutical Delivery Systems." Journal of Nanoscience and Nanotechnology 8, no. 5 (2008): 2216–29. http://dx.doi.org/10.1166/jnn.2008.274.

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Nanobiotechnology, involving biological systems manufactured at the molecular level, is a multidisciplinary field that has fostered the development of nanoscaled pharmaceutical delivery devices. Micelles, liposomes, solid lipid nanoparticles, polymeric nanoparticles, functionalized nanoparticles, nanocrystals, cyclodextrins, dendrimers, nanotubes and metallic nanoparticles have been used as strategies to deliver conventional pharmaceuticals or substances such as peptides, recombinant proteins, vaccines and nucleotides. Nanoparticles and other colloidal pharmaceutical delivery systems modify ma

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35

Vukčević, Marija, Dušan Trajković, Marina Maletić, Miljana Mirković, Aleksandra Perić Grujić, and Dragana Živojinović. "Modified Fly Ash as an Adsorbent for the Removal of Pharmaceutical Residues from Water." Separations 11, no. 12 (2024): 337. http://dx.doi.org/10.3390/separations11120337.

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In this work, different methods for fly ash modification were applied to obtain an adsorbent for the efficient removal of selected pharmaceuticals from a multiclass aqueous solution. Morphological and surface properties of the modified fly ash samples were analyzed by scanning electron microscopy, X-ray fluorescence, X-ray diffraction, Fourier transform infrared spectroscopy, and point of zero charge, and the influence of the applied modifications was determined by comparison with the results obtained for unmodified fly ash. Experimental parameters of the adsorption of the pharmaceutical onto

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Ahmed, Md Dipu, Kazi Madina Maraz, and Saikot Mazumder. "Unveiling molecular secrets: Raman spectroscopy as a versatile tool for advanced analysis and investigation in forensic science and pharmaceuticals." Materials Engineering Research 5, no. 1 (2023): 291–305. http://dx.doi.org/10.25082/mer.2023.01.005.

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The conventional technologies used for identifying, investigating, and analyzing illegal drugs, explosives, and fibers in forensic science often involve destructive methods, preventing re-analysis of evidence. Conversely, a non-destructive approach is crucial for drug characterization, synthesis route development, and identification of counterfeit and adulterated pharmaceuticals. Raman spectroscopy, renowned for its rapid, non-destructive, and cost-effective nature, has emerged as the predominant technique in forensic and pharmaceutical applications. Its inelastic light scattering properties e

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37

Murakami, Jillian N., and Kevin B. Thurbide. "Investigating the properties of subcritical water extraction with pharmaceutical tablets." Canadian Journal of Chemistry 92, no. 1 (2014): 26–32. http://dx.doi.org/10.1139/cjc-2013-0411.

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The properties of subcritical water extraction (SWE) in the sample preparation of pharmaceutical tablets were investigated. Tablets comprised of microcrystalline cellulose excipients broke apart up to 80 times faster in subcritical water than they did in room temperature water, while those containing starch readily broke apart in either. Tablets containing starch were also observed to gelatinize or “paste” over several SWE conditions, impeding subsequent filtration and analysis. This effect was avoidable, however, since it was demonstrated to disappear with increases in extraction time and tem

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38

Emadi, Fatemeh, Arash Emadi, and Ahmad Gholami. "A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets." Current Pharmaceutical Biotechnology 21, no. 11 (2020): 1016–27. http://dx.doi.org/10.2174/1389201021666200318131422.

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Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on t

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39

Vranić, Edina. "Amorphous Pharmaceutical Solids." Bosnian Journal of Basic Medical Sciences 4, no. 3 (2004): 35–39. http://dx.doi.org/10.17305/bjbms.2004.3383.

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Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only “static” structural disorder. The amorphous solids have always been an essential part of pharmaceutical research, but the current interest has been raised by two developments: a growing attention to pharmaceutical solids in general, especially polymorphs and solvates and a revived interest in the science of glasses and the glass transition.Amorphou

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40

Ikram, Muhammad, Ali Haider, and Urooj Fatima. "Pharmaceutical Activity of Medicinal Plant Amaranthus viridis Linn. Due to Its Chemical Constituents: A Review." BIOEDUSCIENCE 7, no. 2 (2023): 143–48. http://dx.doi.org/10.22236/jbes/12089.

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Background: Amaranthus viridis, a herbal plant belonging to the family Amaranthaceae, has gained significant attention in the field of traditional medicine due to its rich chemical composition. This plant is known to contain various bioactive components that contribute to its pharmaceutical value. With its extensive range of chemical compounds, Amaranthus viridis has found applications in therapeutic, pharmaceutics, and cosmetic industries. In this study, we aim to explore the medicinal potential of Amaranthus viridis and investigate its various pharmaceutical activities. Methods: The process

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41

Uchiyama, Satoshi, Nakamura Hirotaka, SungGi Chi, et al. "Properties and Distribution of IDH-1/2 Mutations in Acute Myeloid Leukemia By the Comprehensive Genomic Analysis." Blood 138, Supplement 1 (2021): 4447. http://dx.doi.org/10.1182/blood-2021-149801.

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Abstract Background: Isocitrate dehydrogenase (IDH)-1 and -2 are TCA cycle-involved enzymes which convert isocitrate to alpha-ketoglutarate. Mutations that alter the enzymatic activity causes accumulation of a mal-metabolite D-2-hydroxyglutarate, which results in inhibition of DNA methylation and tumorigenesis. IDH-1 and IDH-2 mutation are present in approximately 7-10% and 10% of patients with acute myeloid leukemia (AML), respectively. Recently, whole exome sequencing has been used for the next-generation sequencing of AML, and certain gene mutations have been identified in patients with AML

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Da Silva, Monique Farias, Vitor Santos Ramos, Zilda Maria Castro De Carvalho, and Maria Inês Bruno Tavares. "BIBLIOGRAPHIC REVIEW OF THE APPLICATION OF CINNAMALDEHYDE AS A DRUG IN DENTISTRY." REVISTA FOCO 17, no. 2 (2024): e4452. http://dx.doi.org/10.54751/revistafoco.v17n2-075.

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Cinnamon (Cinnamomum sp) has been used as a spice for millennia, offering nutritional, aromatic, and pharmaceutical properties. The essential oil from cinnamon bark predominantly contains cinnamaldehyde, which exhibits applications as an antioxidant, anti-inflammatory, antimicrobial, and wound-healing agent. These characteristics have drawn the interest of the pharmaceutical industry, seeking to identify alternative uses of this compound for the treatment of oral diseases. In light of this, the present study aims to conduct a literature review, justifying the potential presented by cinnamon es

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M, Achor, and Zaharadeen U. A. "Binding Properties of Ethyl Starch obtained from Ipomoea batatas as a Pharmaceutical Excipient." International Journal of Pharma Research and Health Sciences 7, no. 3 (2019): 2962–67. http://dx.doi.org/10.21276/ijprhs.2019.03.02.

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ISHIHARA, Hiroshi, Yasushi ISHIHAMA, Itaru ARIMOTO, Ikuo KUSHIDA, and Takashi KAJIMA. "SCREENING OF PHYSICAL PROPERTIES IN PHARMACEUTICAL DISCOVERY." Drug Metabolism and Pharmacokinetics 16, supplement (2001): 160–61. http://dx.doi.org/10.2133/dmpk.16.supplement_160.

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Bhatia, Saurabh, Kiran Sharma, and Tanmoy Bera. "Structural characterization and pharmaceutical properties of porphyran." Asian Journal of Pharmaceutics 9, no. 2 (2015): 93. http://dx.doi.org/10.4103/0973-8398.154698.

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McLoughlin, C. M., W. A. M. McMinn, and T. R. A. Magee. "Physical and dielectric properties of pharmaceutical powders." Powder Technology 134, no. 1-2 (2003): 40–51. http://dx.doi.org/10.1016/s0032-5910(03)00133-5.

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Sang, Vo Thanh, Ngo Dai Hung, and Kim Se-kwon. "Pharmaceutical properties of marine polyphenols: an overview." ACTA Pharmaceutica Sciencia 57, no. 2 (2019): 217. http://dx.doi.org/10.23893/1307-2080.aps.05714.

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Singh, Inderbir, Ashish K. Rehni, Pradeep Kumar, Manoj Kumar, and Hassan Y. Aboul‐Enein. "Carbon Nanotubes: Synthesis, Properties and Pharmaceutical Applications." Fullerenes, Nanotubes and Carbon Nanostructures 17, no. 4 (2009): 361–77. http://dx.doi.org/10.1080/15363830903008018.

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Shalaev, Evgenyi, Ke Wu, Sheri Shamblin, Joseph F. Krzyzaniak, and Marc Descamps. "Crystalline mesophases: Structure, mobility, and pharmaceutical properties." Advanced Drug Delivery Reviews 100 (May 2016): 194–211. http://dx.doi.org/10.1016/j.addr.2016.04.002.

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Jansook, Phatsawee, Noriko Ogawa, and Thorsteinn Loftsson. "Cyclodextrins: structure, physicochemical properties and pharmaceutical applications." International Journal of Pharmaceutics 535, no. 1-2 (2018): 272–84. http://dx.doi.org/10.1016/j.ijpharm.2017.11.018.

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