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Journal articles on the topic 'Pharmaceutical residue'

Author: Grafiati

Published: 24 May 2025

Last updated: 31 July 2025

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1

P, Aastha Dhingra1 Sirajuddin Ahmed*2 Weqar Ahmed Siddiqui1 Siddhartha Gautam3 &. Nadeem A. Khan2. "IDENTIFICATION OF PRIORITY PHARMACEUTICAL RESIDUES IN HOSPITAL EFFLUENTS." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES 5, no. 7 (2018): 420–35. https://doi.org/10.5281/zenodo.1320966.

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The pharmaceutical residues are commonly found in aquatic environment throughout the world. The pharmaceutical residue increases the microbial resistance, reduces the self purification capacities of the water bodies, adversely impacts the aquatic life being ecotoxic and few are also known to be teratogenic, mutagenic and even genotoxic. Despite of well documented and known potential implications of pharmaceutical residues, they persist in the aquatic environment and there are still no specific discharge standards. This study has attempted to consider extensive set of important parameters for i

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2

Barceló, Damià. "Pharmaceutical-residue analysis." TrAC Trends in Analytical Chemistry 26, no. 6 (2007): 454–55. http://dx.doi.org/10.1016/j.trac.2007.02.008.

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3

Coyne, C. P., Joseph E. Smith, and Kerry Keeton. "Additive and synergistic pharmacologic inhibition of equine fibrinoligase (factor XIIIa*-like) biochemical activity." American Journal of Veterinary Research 53, no. 11 (1992): 2058–66. http://dx.doi.org/10.2460/ajvr.1992.53.11.2058.

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Summary A selected group of pharmaceutical compounds were evaluated for the ability to inhibit the biochemical activity of fibrinoligase (coagulation factor XIIIa*) in pooled equine plasma. Criteria for the pharmaceuticals selected were based on the mechanism of the transglutamination biochemical reaction mediated by coagulation factor XIIa*. These criteria were complemented by recognition of the molecular configuration and chemical composition of amino acid residue side chains involved in the process of covalent fibrin monomer polymerization (cross-linking, transglutamination) mediated by thi

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Choi, Miyoung, Dong Whan Choi, Jung Yeol Lee, Young Suk Kim, Bun Su Kim, and Byoung Ho Lee. "Removal of pharmaceutical residue in municipal wastewater by DAF (dissolved air flotation)–MBR (membrane bioreactor) and ozone oxidation." Water Science and Technology 66, no. 12 (2012): 2546–55. http://dx.doi.org/10.2166/wst.2012.429.

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Growing attention is given to pharmaceutical residue in the water environment. It is known that pharmaceuticals are able to survive from a series of wastewater treatment processes. Concerns regarding pharmaceutical residues are attributed to the fact that they are being detected in water and sediment environment ubiquitously. Pharmaceutical treatment using a series of wastewater treatment processes of the DAF (dissolved air flotation)–MBR (membrane bioreactor)–ozone oxidation was conducted in the study. DAF, without addition of coagulant, could remove CODcr (chemical oxygen demand by Cr) up to

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Sadik Hameed Ftaysa and Raheem Aziz Hussein Al-Uqaily. "Evaluation the pharmaceutical residue risks in Tigris River in Wasit Governorate, Iraq." GSC Advanced Research and Reviews 23, no. 2 (2025): 001–12. https://doi.org/10.30574/gscarr.2025.23.2.0123.

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The objective of the present study was to evaluate the risks associated with pharmaceutical residues in the surface water of the Tigris River located in the Wasit Governorate of Iraq. This research provided a comprehensive analysis encompassing physical, chemical, and microbiological parameters of the surface water along the Tigris River during the study period from October 2023 to July 2024. The findings included minimum, maximum, average, and standard deviation values for each parameter assessed. Given the critical issue of pharmaceutical contamination in the aquatic environment of the Tigri

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Zhang, Zhefan, Lingchao Cai, and Liangliang Song. "Peptide Diversification through Addition Reaction of Free Carboxylic Acids to Ynamides." Processes 11, no. 8 (2023): 2262. http://dx.doi.org/10.3390/pr11082262.

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Peptide modification has emerged as an important topic in the academic community and pharmaceutical industry. However, they are primarily focused on the diversification of amines, thiols, and alcohols. Direct and chemoselective modification of acid residues in peptides is relatively underdeveloped. In this context, we report a novel and efficient method for the direct functionalization of acid residues in peptides. By using ynamides as reaction partners, the adducts are rapidly obtained in moderate to excellent yields at room temperature in water. This approach shows excellent chemoselectivity

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Nandan, K. Dhir, and K. Yadav S. "Estimation of Clotrimazole residue in swab samples via validated UPLC method." Journal of Indian Chemical Society Vol. 89, Dec 2012 (2012): 1665–70. https://doi.org/10.5281/zenodo.5772122.

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Ravishankar College, Bhanpur Chouraha, Bhopal-462 010, Madhya Pradesh, India Quality Control Head - Glenmark Pharmaceutical Ltd. <em>Manuscript received online 22 February 2012, revised 28 March 2012, accepted 30 March 2012</em> An ultra performance liquid chromatographic (UPLC) method was developed for simultaneous determination of antifungal ointment and active pharmaceutical ingredient (API) residues. A new, generic method is presented, with which it is possible to verify the cleaning process of antifungal drug producing equipment line used for the production of various pharmaceuticals. The

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Yuba, Eiji, Yoshiki Fukaya, Shin Yanagihara, Nozomi Kasho, and Atsushi Harada. "Development of Mannose-Modified Carboxylated Curdlan-Coated Liposomes for Antigen Presenting Cell Targeted Antigen Delivery." Pharmaceutics 12, no. 8 (2020): 754. http://dx.doi.org/10.3390/pharmaceutics12080754.

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Specific delivery to antigen presenting cells (APC) and precise control of the intracellular fate of antigens are crucial to induce cellular immunity that directly and specifically attacks cancer cells. We previously achieved cytoplasmic delivery of antigen and activation of APC using carboxylated curdlan-modified liposomes, which led to the induction of cellular immunity in vivo. APCs express mannose receptors on their surface to recognize pathogen specifically and promote cross-presentation of antigen. In this study, mannose-residue was additionally introduced to carboxylated curdlan as a ta

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Kraskouskaya, Dziyana, Joel A. Drewry, Eugenia Duodu, et al. "Exploring the structural determinants of selective phosphopeptide recognition using bivalent metal-coordination complexes." MedChemComm 4, no. 1 (2013): 289–92. http://dx.doi.org/10.1039/c2md20342a.

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We demonstrate that Lewis acidic coordination complexes equipped with cationic binding groups might be best utilized as selective receptors for binding phosphopeptides with anionic side chain residues proximal to the phosphorylated residue.

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10

Delfau-Bonnet, Guillaume, Nabila Imatoukene, Tiphaine Clément, Michel Lopez, Florent Allais, and Anne-Lise Hantson. "Evaluation of the Potential of Lipid-Extracted Chlorella vulgaris Residue for Yarrowia lipolytica Growth at Different pH Levels." Marine Drugs 20, no. 4 (2022): 264. http://dx.doi.org/10.3390/md20040264.

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Projections show that the cultivation of microalgae will extend to the production of bio-based compounds, such as biofuels, cosmetics, and medicines. This will generate co-products or residues that will need to be valorized to reduce the environmental impact and the cost of the process. This study explored the ability of lipid-extracted Chlorella vulgaris residue as a sole carbon and nitrogen source for growing oleaginous yeasts without any pretreatment. Both wild-type Yarrowia lipolytica W29 and mutant JMY3501 (which was designed to accumulate more lipids without their remobilization or degra

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Pratiwi, Rimadani, Shinta Permata Ramadhanti, Asyifa Amatulloh, Sandra Megantara, and Laila Subra. "Recent Advances in the Determination of Veterinary Drug Residues in Food." Foods 12, no. 18 (2023): 3422. http://dx.doi.org/10.3390/foods12183422.

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The presence of drug residues in food products has become a growing concern because of the adverse health risks and regulatory implications. Drug residues in food refer to the presence of pharmaceutical compounds or their metabolites in products such as meat, fish, eggs, poultry and ready-to-eat foods, which are intended for human consumption. These residues can come from the use of drugs in the field of veterinary medicine, such as antibiotics, antiparasitic agents, growth promoters and other veterinary drugs given to livestock and aquaculture with the aim of providing them as prophylaxis, th

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Efriem, Solomon, Malka Britzi, Stefan Soback, Chris Sabastian, and Sameer J. Mabjeesh. "A Multi-Residue Analytical Method for Assessing the Effects of Stacking Treatment on Antimicrobial and Coccidiostat Degradation in Broiler Litter." Pharmaceuticals 17, no. 2 (2024): 203. http://dx.doi.org/10.3390/ph17020203.

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Antimicrobial drugs and coccidiostat compounds are commonly used in poultry farming. These compounds are subsequently excreted and released into the environment via broiler litter (BL) and can re-enter the food chain as fertilizer or animal feed. Such residue in animal feed can encourage the appearance of antibiotic-resistant bacteria as well as toxicity. Most analytical methods used to identify and quantitate these drug residues are traditional, and are specific to some antimicrobials and present limitations in assessing complex matrixes like BL. The aim of this study was to develop a multi-r

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Bejenaru, Ludovic Everard, Antonia Radu, Adina-Elena Segneanu, et al. "Innovative Strategies for Upcycling Agricultural Residues and Their Various Pharmaceutical Applications." Plants 13, no. 15 (2024): 2133. http://dx.doi.org/10.3390/plants13152133.

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This review investigates innovative strategies for upcycling agricultural residues into valuable pharmaceutical compounds. The improper disposal of agricultural residues contributes to significant environmental issues, including increased greenhouse gas emissions and ecosystem degradation. Upcycling offers a sustainable solution, transforming these residues into high-value bioproducts (antioxidants, antitumor agents, antidiabetic compounds, anti-inflammatory agents, and antiviral drugs). Nanotechnology and microbial biotechnology have a crucial role in enhancing bioavailability and targeted de

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Suharyani, Ine, Iin Indawati, Encu Asep Setiadi, Maisya Mauliana Insani, and Ibnu Mas'ud. "REVIEW: THE USE OF TOFU RESIDUE IN THE PHARMACEUTICS." Medical Sains : Jurnal Ilmiah Kefarmasian 9, no. 1 (2024): 271–76. http://dx.doi.org/10.37874/ms.v9i1.1096.

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Tofu is a processed soy product consisting of soft solids made by clumping soy protein extracts. The residual result of tofu processing is called the tofu dredging waste. In Indonesia, tofu waste remains an unsolved problem. Many people argue that the waste from tofu processing (tofu residue waste) does not have high economic value and is only used as feed for livestock and is even thrown carelessly into the river, which causes damage to the ecosystem. Tofu pulp has high nutritional content, such as protein (26.6%), fat (18.3%), carbohydrates (41.3%), phosphorus (0.29%), calcium (0.19%), iron

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Brati, Ediolane Hilbert, Tássio Dresch Rech, Lenita Agostinetto, and Ana Emilia Siegloch. "Disposal of pharmaceuticals wastes by the population of an outcrop area of the Guarani Aquifer System in Southern Brazil." Research, Society and Development 10, no. 11 (2021): e214101119021. http://dx.doi.org/10.33448/rsd-v10i11.19021.

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Pharmaceutical waste is considered emerging pollutant that can contaminate water sources and underground water, besides is serious problem for waste management in Brazil. The objective of this study was to evaluate the pharmaceutical consumption for human use and the way expired and unused medicines are disposed by the population. The study was carried out in two neighborhoods of the Lages, under outcrop of the Guarani Aquifer, in southern Brazil. In this descriptive and quantitative study, data collection occurred between August and October of 2018 via a questionnaire completed by 309 partici

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Ambrus, Árpád, Vy Vy Ngoc Doan, Júlia Szenczi-Cseh, Henriett Szemánné-Dobrik, and Adrienn Vásárhelyi. "Quality Control of Pesticide Residue Measurements and Evaluation of Their Results." Molecules 28, no. 3 (2023): 954. http://dx.doi.org/10.3390/molecules28030954.

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Pesticide residues are monitored in many countries around the world. The main aims of the programs are to provide data for dietary exposure assessment of consumers to pesticide residues and for verifying the compliance of the residue concentrations in food with the national or international maximum residue limits. Accurate residue data are required to reach valid conclusions in both cases. The validity of the analytical results can be achieved by the implementation of suitable quality control protocols during sampling and determination of pesticide residues. To enable the evaluation of the rel

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S, Shamshalniha, and Anbu N. "ANALYSIS OF CHEMICAL CONTAMINANTS IN SEVVIYADHI CHOORANAM." International Journal of Research in Ayurveda and Pharmacy 14, no. 5 (2023): 22–26. http://dx.doi.org/10.7897/2277-4343.1405139.

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Aim: The aim of the study was to analyze the chemical contaminants such as heavy metals, aflatoxins and pesticide residues in Siddha polyherbal formulation Sevviyadhi Chooranam, in powder form is indicated for the treatment and management of Sinusitis. Materials and Methods: Sevviyadhi Chooranam, the Siddha polyherbal formulation was prepared as per GMP (Good Manufacturing Practices) guidelines. The formulation was analyzed for heavy metals such as mercury, arsenic, lead and cadmium, aflatoxins such as aflatoxin B1, B2, G1, G2 and pesticide residues such as organochlorine pesticides, organopho

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C., Febina, and Biju Chacko. "Effect of Dietary Incorporation of Ayurvedic Pharmaceutical Tiktaka Gritham Residue on Haemato-Biochemical Parameters of Malabari Kids." Indian Journal of Pure & Applied Biosciences 10, no. 4 (2022): 14–20. http://dx.doi.org/10.18782/2582-2845.8935.

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A feeding trial of 90 days duration was conducted to study the effect of dietary incorporation of ayurvedic pharmaceutical Tiktaka gritham residue based diet on various haemato-biochemical parameters of Malabari kids. Fifteen healthy three months old Malabari kids were selected and divided into three groups of five each, as uniformly as possible regarding body weight, sex and age. The dietary treatments were T1 (control diet), T2 and T3 kid starter incorporated with 10 and 20 per cent of ayurvedic pharmaceutical Tiktaka gritham residue, respectively. Haematobiochemical parameters of the experi

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Togola, Anne, and Hélène Budzinski. "Multi-residue analysis of pharmaceutical compounds in aqueous samples." Journal of Chromatography A 1177, no. 1 (2008): 150–58. http://dx.doi.org/10.1016/j.chroma.2007.10.105.

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Meng, Fanjing, Tingtao Chen, Dongwen Ma, et al. "Reclamation of Herb Residues Using Probiotics and Their Therapeutic Effect on Diarrhea." Mediators of Inflammation 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/4265898.

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Residues from herbal medicine processing in pharmaceutical plants create a large amount of waste (herb residues), which consists mainly of environmental pollution and medicinal waste. In order to resolve this problem, probiotics ofBacillus (B.) subtilis,Aspergillus (A.) oryzae, andLactobacillus (L.) plantarumM3 are selected to reuse herb residue of Jianweixiaoshi tablets (JT), and an antibiotic-associated diarrhea (AAD) mouse model was established to evaluate the therapeutic effects of the herb residue fermentation supernatant. Our results indicated that the fermentation supernatant had scaven

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Sandín-España, Pilar, Miguelina Mateo-Miranda, Carmen López-Goti, Elena Seris-Barrallo, and José-Luis Alonso-Prados. "Analysis of Pesticide Residues by QuEChERS Method and LC-MS/MS for a New Extrapolation of Maximum Residue Levels in Persimmon Minor Crop." Molecules 27, no. 5 (2022): 1517. http://dx.doi.org/10.3390/molecules27051517.

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According to EU guidance SANCO/7525/VI/95 Rev. 10.3, residue data extrapolation from a surrogate major crop to a minor crop can be used for setting maximum residue levels (MRLs) with a reduced number of residue trials and representative selected pesticides. In this work, a QuEChERS method (citrate-buffered version and PSA with MgSO4 clean-up) and LC-ESI-MS/MS for the determination of boscalid, pyraclostrobin, fludioxonil, fluopyram and tebuconazole in persimmon was developed and validated according to EU Commission guidelines and afterwards used for the determination of residues in four field

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Martins, Rui R., André M. P. T. Pereira, Liliana J. G. Silva, Sofia C. Duarte, Andreia Freitas, and Angelina Pena. "Impact of Cooking Procedures on Coccidiostats in Poultry Muscle." Antibiotics 14, no. 6 (2025): 586. https://doi.org/10.3390/antibiotics14060586.

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Background/Objectives: Poultry meat is a popular and nutritious food, valued for its high protein content and healthy fat profile. However, like other animal products, it can contain pharmaceutical residues, including coccidiostats, antimicrobials commonly used to prevent parasitic infections caused by Eimeria species. While most monitoring focuses on raw meat, it is important to understand how these compounds behave during cooking to assess potential health risks better and ensure food safety. Methods: This study examined how five different cooking methods (roasting, grilling, and microwaving

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Nguyen, Ngoc-Van Thi, Kim-Ngan Huynh Nguyen, Tuyet-Ngan Duong, Van De Tran, Kyeong Ho Kim, and Lien To Thi Pham. "Evaluation of pesticide residues in vegetables from Mekong, Delta, Vietnam using LC-MS/MS." Tropical Journal of Pharmaceutical Research 20, no. 7 (2022): 1497–504. http://dx.doi.org/10.4314/tjpr.v20i7.24.

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Purpose: To assess the levels of pesticide residues in commonly used vegetables in Vietnam as a reference for future monitoring. Methods: A total of 180 samples of six different fresh vegetables including watercress, mustard green, choy sum, daikon, okra, and yam were analyzed from Mekong Delta, Vietnam. Ten popular pesticides were evaluated using liquid chromatography-tandem mass spectrometry (LC-MS/MS) after extraction with a multi-residue method (QuEChERS method). Results: The results were assessed according to the maximum residue limit (MRL) provided by Codex for each pesticide

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Vovk, Irena, and Breda Simonovska. "TLC Determination of Mebendazol and Pentoxifylline as Residues on Pharmaceutical Equipment Surfaces." Journal of AOAC INTERNATIONAL 84, no. 4 (2001): 1258–64. http://dx.doi.org/10.1093/jaoac/84.4.1258.

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Abstract This paper presents the applicability of thin-layer chromatographic methods with a subsequent densitometric or video densitometric quantitation for determination of residues in controlling pharmaceutical equipment cleanliness. Analytical methods were developed for monitoring residues of pentoxifylline at 10 mg/m2 and mebendazol at 1 mg/m2 on stainless steel surfaces. Simulated samples were prepared by addition of a calculated amount of pharmaceutical (as a solution) on a 35 × 35 cm stainless steel surface. After evaporation of solvent, the residues were wiped with wetted cotton. The c

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Vovk, Irena, and Breda Simonovska. "Development and Validation of a Thin-Layer Chromatographic Method for Determination of Chloramphenicol Residues on Pharmaceutical Equipment Surfaces." Journal of AOAC INTERNATIONAL 88, no. 5 (2005): 1555–61. http://dx.doi.org/10.1093/jaoac/88.5.1555.

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Abstract A thin-layer chromatographic (TLC) method with densitometric quantitation using the absorption reflectance mode at 280 nm was developed and validated for the determination of chloramphenicol residues in controlling pharmaceutical equipment cleanliness. Simulated samples at residue levels 0.5, 1, and 1.2 mg/m2 were prepared by spreading the calculated amount of chloramphenicol solution on a 10 dm2 stainless steel surface. After evaporation of the solvent, the residue was removed by 2 methanol-wetted cotton swabs, which were then extracted with methanol. The extract was applied on a hig

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Khurana, Pratishtha, Samreen Sran, Ratul Kumar Das, Luz Sanchez-Silva, and Satinder Kaur Brar. "High-capacity adsorption of fluoxetine using olive-stone derived activated biochar: insights into efficiency and mechanism." RSC Advances 15, no. 25 (2025): 20330–40. https://doi.org/10.1039/d5ra01258a.

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Sibagatullina, Elena R., Ruslan R. Yapaev, Ekaterina S. Volkova, Ekaterina E. Firsova, Alina R. Valieva, and Klara E. Stankevich. "EXPERIENCE IN OBTAINING PRODUCTS OF THE DELAYED COKING PROCESS USING VISBREAKING RESIDUE AND CATALYTIC CRACKING HEAVY GAS OIL AS FEEDSTOCK." Oil and Gas Business, no. 2 (May 19, 2023): 204–17. http://dx.doi.org/10.17122/ogbus-2023-2-204-217.

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The authors have analyzed the literature data on delayed coking process. There have been considered the following: feedstock bases for petroleum coke production; implementation and development of delayed coking process; the types of products obtained. It has been revealed, that the main feedstocks for the process are heavy fractions of oil: fuel oil, semihudron, tar, various heavy oil residues, etc.In order to expand the feedstock base, the authors conducted laboratory studies concerning the use of visbreaking residue and catalytic cracking heavy gas oil in the coking process. During the resea

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Khairunniza, N., and M. K. Aliyu. "Public practice on the unused pharmaceutical waste and the effect on surface water." IOP Conference Series: Earth and Environmental Science 1205, no. 1 (2023): 012003. http://dx.doi.org/10.1088/1755-1315/1205/1/012003.

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Abstract Pharmaceutical waste is a waste that kept piling up by the days due to the increasing production of it. This issue leads to the detection of pharmaceutical waste residue in the water surface based on the previous studies that were conducted. This study was conducted to know the public practice on how they dispose of their unused pharmaceutical waste and help them to know the effect of that action to the water. A questionnaire was distributed to the target respondents to know their practice on how they dispose of the waste and the collected data were analysed to evaluate the public awa

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Kumar, Virendra, and Archana Shrivastav. "Molecular Identification of Azithromycin Antibiotic Degradation Bacteria Isolated from Pharmaceutical Waste." International Journal of Current Microbiology and Applied Sciences 12, no. 4 (2023): 192–99. http://dx.doi.org/10.20546/ijcmas.2023.1204.022.

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The biological removal of antibiotic residue in the environment has earned great interest. This study presented the biodegradation of azithromycin using B. cereus isolated from pharmaceutical waste. This azithromycin-degrading bacterial strain grew well in the range of temperatures between 25°C and 40°C under aerobic condition. On the basis of the observation of the morphology, Gram staining, the determination of biochemistry as well as the subsequent analyse of 16S rDNA, the No. 2 bacteria was identified as B. cereus strain. B. cereus also indicated the possibility to use for treating azithro

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Zheng, Kunming, Xiaoping Wu, Jiannan Chen, et al. "Establishment of an LC-MS/MS Method for the Determination of 45 Pesticide Residues in Fruits and Vegetables from Fujian, China." Molecules 27, no. 24 (2022): 8674. http://dx.doi.org/10.3390/molecules27248674.

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Pesticide residues in food have become an important factor seriously threatening human health. Therefore, this study was conducted to determine the pesticide residues in fruits and vegetables commonly found in Fujian, China, with the aim of constructing a simple and rapid method for pesticide residue monitoring. We collected 5607 samples from local markets and analyzed them for the presence of 45 pesticide residues. A fast, easy, inexpensive, effective, robust, and safe (QuEChERS) multi-residue extraction method followed by liquid chromatography equipped with triple-quadrupole mass spectrometr

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Khierallah, Amna Hassan Issa, Amel Hadj Bouazza, and Daniel Montplaisir. "Nanofibrous material of n-succinyl chitosan/ polyethylene oxide in the removal of emerging pharmaceuticals from aqueous solution by adsorption/desorption method." BioResources 18, no. 1 (2023): 1971–98. http://dx.doi.org/10.15376/biores.18.1.1971-1998.

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Pharmaceutical metabolites and their residues have been identified as major environmental pollutants in aquatic ecosystems. N-succinyl chitosan (NSCS) was studied as a potential adsorbent for a pharmaceutical residue, fluoxetine, from aqueous media. NSCS was investigated using Fourier transform infrared (FTIR) and 1H-nuclear magnetic residence (NMR) spectroscopies. Scanning electron microscopy (SEM) was used to investigate the formation of nanofibers by electrospinning of these green biomaterial polymer membranes. The mechanisms of FLX adsorption, as well as the effects of pH value in the orig

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Farkas, Dóra, Nikolett Kállai-Szabó, and István Antal. "Foams as carrier systems for pharmaceuticals and cosmetics." Acta Pharmaceutica Hungarica 89, no. 1 (2019): 5–15. http://dx.doi.org/10.33892/aph.2019.89.5-15.

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Foams are becoming more and popular in several areas of our lives, including pharmaceutics and cosmetics. They are colloid systems where gas is dispersed in liquid phase Active ingredient bearing pharmaceutical foams are traditionally applied topically (dermal, local rectal, vaginal), but formulations for other delivery routes (e.g. nanosystems parenterally, solid foams orally) are also available. Numerous advantages are attached to foams when compared to traditional vehicles, resulting in increased patient compliance. Amongst others, the suitable composition contributes to quick, oily residue

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Su, Qi, Jiangyan Huo, Yibin Wang, et al. "The Obesity Amelioration Effect in High-Fat-Diet Fed Mice of a Homogeneous Polysaccharide from Codonopsis pilosula." Molecules 27, no. 16 (2022): 5348. http://dx.doi.org/10.3390/molecules27165348.

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A homogeneous polysaccharide coded as CPP−1 was extracted and purified from the root of Codonopsis pilosula (Franch.) Nannf. by water extraction, ethanol precipitation, and column chromatography. Its structure was analyzed by HPGPC-ELSD, HPLC, GC-MS, FT-IR, and NMR techniques. The results indicated that CPP−1 was composed of mannose (Man), glucose (Glc), galactose (Gal), and arabinose (Ara) at a molar ratio of 5.86 : 51.69 : 34.34 : 8.08. The methylation analysis revealed that the main glycosidic linkage types of CPP−1 were (1→)-linked-Glc residue, (1→3)-linked-Glc residues, (1→4)-linked-Gal r

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Tian, Shuge, Qianqian Song, Wenxia Wu, and Xiaoying Zhou. "Effect of Microwave Vacuum Drying on the Drying Characteristics and Chemical Compositions of Turkish Gall Residues." IOP Conference Series: Earth and Environmental Science 966, no. 1 (2022): 012017. http://dx.doi.org/10.1088/1755-1315/966/1/012017.

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Abstract Recently, the secondary use of waste has received increasing attention. The raw material of Xipayi mouth rinse is Turkish gall. During the industrial production of Xipayi mouth rinse, a lot of gall residues are produced. If these drugs are directly discarded, it will cause waste of resources and also bring pressure to the ecological environment. Previous studies have found that the active ingredient content of Turkish gall residues remains high, therefore the residues are still a valuable resource for exploitation. This study aimed to evaluate the effect of the chemical compositions a

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Sutrisno, Hendri, and Fitriana Meilasari. "Review: Medical Waste Management for Covid19." JURNAL KESEHATAN LINGKUNGAN 12, no. 1si (2020): 104. http://dx.doi.org/10.20473/jkl.v12i1si.2020.104-120.

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Introduction: Medical waste generation during the Covid19 pandemic increased by around 30%. Sources of medical waste generation are health care activities. If medical waste is not appropriately managed, it can pollute the environment and disturb health. The purpose of the review is to identify the potential of medical waste in health-care facilities in Indonesia when the Covid19 pandemic and to review medical waste management in Indonesia. The analysis uses a systematic literature review. Discussion: The potential of medical waste during the Covid19 epidemic is infectious waste (PPE wastes), s

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Widhi, Anriani Puspita Karunia Ning, and Imam Nafi Yana Saputra. "Residu Antibiotik Serta Keberadaan Escherichia Coli Penghasil ESBL pada Daging Ayam Broiler di Pasar Kota Purwokerto." Jurnal Kesehatan Lingkungan Indonesia 20, no. 2 (2021): 137–42. http://dx.doi.org/10.14710/jkli.20.2.137-142.

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Latar belakang: Pemenuhan kebutuhan pangan asal ternak yang berasal dari unggas memiliki angka konsumsi yang cukup tinggi salah satunya yaitu ayam broiler. Untuk memenuhi tingginya permintaan terhadap ayam broiler pada pakandiberifeed additiveserta antibiotic growth promotor (AGP) dalam bentuk antibiotik untuk mempercepat pertumbuhan dan daya tahan tubuh. Pemanfaatan antibiotik yang tidak bijak akan menimbulkan residu antibiotik serta resistensi Escherichia coli penghasil Extended Spectrum β-lactamase (ESBL).Metode: Penelitian ini termasuk penelitian deskriptif. Data primer diperoleh dari hasi

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Xu, Xifei, Xuejing Zhang, Mubai Sun, et al. "Optimization of Mixed Fermentation Conditions of Dietary Fiber from Soybean Residue and the Effect on Structure, Properties and Potential Biological Activity of Dietary Fiber from Soybean Residue." Molecules 28, no. 3 (2023): 1322. http://dx.doi.org/10.3390/molecules28031322.

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Soybean residue is a by-product of soybean product production that is wasted unreasonably at present. Accomplishing the efficient utilization of soybean residue can save resources. A composite microbial system was constructed using lactic acid bacteria (LAB) and Saccharomyces cerevisiae (SC), and modified soybean residue was prepared by solid fermentation. In order to explore the value of modified soybean residue as a food raw material, its physical and chemical properties, adsorption properties, and antioxidant properties were studied. The results showed that the soluble dietary fiber (SDF) y

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Adil, Maryam, Muhammad Riaz, Muhammad Arif, and Kashif Akhtar. "Sources, Persistence, Ecotoxicology and Transformations of Anticancer Pharmaceutical Drug Residues in the Soil Environment: A Review." Journal of Soil, Plant and Environment 2, no. 2 (2023): 28–46. http://dx.doi.org/10.56946/jspae.v2i2.215.

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Release and environmental consequences of drug residues pose a major challenge for soil quality management. This review aims to synthesis the literature related to the transformations of anticancer drugs at the soil-water interphase and their ecological effects. Pharmaceutical drugs, including anticancer drugs originate form point and non-point sources of human and animal background. While detrimental effects of anticancer drug residues on human health are widely reported, a relatively little body of knowledge focuses on their persistence, decomposition and interaction with soil biological hea

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Takayama, Mitsuo. "Transient Conformations Leading to Peptide Fragment Ion [c + 2H]+ via Intramolecular Hydrogen Bonding Using MALDI In-source Decay Mass Spectrometry of Serine-, Threonine-, and/or Cysteine-Containing Peptides." Molecules 28, no. 23 (2023): 7700. http://dx.doi.org/10.3390/molecules28237700.

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The formation of a peptide fragment ion [c + 2H]+ was examined using ultraviolet matrix-assisted laser desorption/ionization in-source decay mass spectrometry (UV/MALDI-ISD MS). Unusually, an ISD experiment with a hydrogen-abstracting oxidative matrix 4-nitro-1-naphthol (4,1-NNL) resulted in a [c + 2H]+ ion when the analyte peptides contained serine (Ser), threonine (Thr), and/or cysteine (Cys) residues, although the ISD with 4,1-NNL merely resulted in [a]+ and [d]+ ions. The [c + 2H]+ ion observed could be rationalized through intramolecular hydrogen atom transfer (HAT), like a Type-II reacti

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Koloka, Ourania, Marioanna Koulama, Dimitra Hela, Triantafyllos Albanis, and Ioannis Konstantinou. "Determination of Multiclass Pharmaceutical Residues in Milk Using Modified QuEChERS and Liquid-Chromatography-Hybrid Linear Ion Trap/Orbitrap Mass Spectrometry: Comparison of Clean-Up Approaches and Validation Studies." Molecules 28, no. 16 (2023): 6130. http://dx.doi.org/10.3390/molecules28166130.

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A multi-residue method was developed to identify and quantify pharmaceutical drug residues in full-fat milk, using a modified QuEChERS extraction procedure and sonication combined with Ultra-High-Performance Liquid Chromatography–High-Resolution Orbitrap Mass Spectrometry (UHPLC-HR-Orbitrap-MS). Sample preparation involves three different QuEChERS extraction procedures and sorbents for the purification step. The optimized modified extraction method, combined with the clean-up approaches using C18 and the EMR-Lipid sorbent, has been validated in terms of linearity, recovery, precision, LOD and

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YİRÜN, Anıl, Pınar ERKEKOĞLU, and Belma KOÇER-GÜMÜŞEL. "Cleaning Validation and Toxicological Evaluation of Residue Levels in Pharmaceutical Manufacturing." Journal of Literature Pharmacy Sciences 7, no. 3 (2018): 227–36. http://dx.doi.org/10.5336/pharmsci.2018-61200.

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Rosman, Nurafiqah, W. N. W. Salleh, Mohamad Azuwa Mohamed, J. Jaafar, A. F. Ismail, and Z. Harun. "Hybrid membrane filtration-advanced oxidation processes for removal of pharmaceutical residue." Journal of Colloid and Interface Science 532 (December 2018): 236–60. http://dx.doi.org/10.1016/j.jcis.2018.07.118.

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Wu, Xiaoqin, Jeremy Landon Conkle, and Jay Gan. "Multi-residue determination of pharmaceutical and personal care products in vegetables." Journal of Chromatography A 1254 (September 2012): 78–86. http://dx.doi.org/10.1016/j.chroma.2012.07.041.

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Ma, Jiahua, Chao Xin, and Chengjia Tan. "Preparation, physicochemical and pharmaceutical characterization of chitosan from Catharsius molossus residue." International Journal of Biological Macromolecules 80 (September 2015): 547–56. http://dx.doi.org/10.1016/j.ijbiomac.2015.07.027.

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Asanga, Edet E., Godwin O. Igile, Olorunfemi A. Eseyin, et al. "Isolation of a pentacyclic triterpenoid from the antiplasmodial bioactive fraction of Nauclea latifolia (Sm) roots." Tropical Journal of Pharmaceutical Research 21, no. 3 (2022): 611–18. http://dx.doi.org/10.4314/tjpr.v21i3.22.

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Purpose: To research the antiplasmodial property of aqueous extract, fractions, and residue of Nauclea latifolia roots and to isolate the components responsible for the antiplasmodial activity.Methods: Roots of N. latifolia were macerated with distilled water; the extract was obtained, successively partitioned with ethyl acetate and butanol. The extract, fractions, and the residue obtained were evaluated for their in vivo antiplasmodial activity and compared with amodiaquine and artesunate. The residue (which exhibited the best therapeutic index) was subjected to column and thin layer chromato

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Spoerk, Martin, Ioannis Koutsamanis, Josip Matić, et al. "Novel Cleaning-in-Place Strategies for Pharmaceutical Hot Melt Extrusion." Pharmaceutics 12, no. 6 (2020): 588. http://dx.doi.org/10.3390/pharmaceutics12060588.

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To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity in pharmaceutical applications, necessitates extensive manual labour and costs. The present work tackles the HME cleaning issue by investigating two cleaning strategies following the extrusion of polymeric formulations of a hormonal drug and for a sustained release formulation of a poorly soluble drug. First, an in-line quantification by means of

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Zeng, Zhi, Jiahui Xiao, Manzhi Li, Jiahui Wu, and Taiping Zhang. "Degradation of Phenol by Immobilized Alcaligenes faecalis Strain JH1 in Fe3O4-Modified Biochar from Pharmaceutical Residues." Water 15, no. 23 (2023): 4084. http://dx.doi.org/10.3390/w15234084.

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The effect and mechanism of phenol removal by immobilized microorganisms in Fe3O4 nanomaterial-modified pharmaceutical residue biochar was investigated to develop efficient biochar immobilizing microbial technology. Plant residue biochar (Y3, Y5, and Y7) was prepared from Andrographis paniculata plant residues as the raw material at 300 °C, 500 °C, and 700 °C, respectively. Y7 was modified with Fe3O4 nanomaterial (Fe-Y7). These four kinds of biochars were used as carriers to adsorb immobilized Alcaligenes faecalis strain JH1, JY3, JY5, JY7, and Fe-Y7 to investigate the mechanism of phenol remo

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Ramos-Martín, Francisco, Claudia Herrera-León, Viviane Antonietti, Pascal Sonnet, Catherine Sarazin, and Nicola D’Amelio. "Antimicrobial Peptide K11 Selectively Recognizes Bacterial Biomimetic Membranes and Acts by Twisting Their Bilayers." Pharmaceuticals 14, no. 1 (2020): 1. http://dx.doi.org/10.3390/ph14010001.

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K11 is a synthetic peptide originating from the introduction of a lysine residue in position 11 within the sequence of a rationally designed antibacterial scaffold. Despite its remarkable antibacterial properties towards many ESKAPE bacteria and its optimal therapeutic index (320), a detailed description of its mechanism of action is missing. As most antimicrobial peptides act by destabilizing the membranes of the target organisms, we investigated the interaction of K11 with biomimetic membranes of various phospholipid compositions by liquid and solid-state NMR. Our data show that K11 can sele

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Elsamman, Sama, Nouran Abdelkader, and Samar Mansour. "Cleaning Validation Model for Tablet Production Line." Pharmaceutical Science and Technology 9, no. 1 (2025): 27–36. https://doi.org/10.11648/j.pst.20250901.14.

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In pharmaceutical manufacturing, cleaning validation is essential for demonstrating the reliability and efficiency of cleaning methods for production equipment. This documented process ensures that cleaning practices effectively and consistently prevent cross-contamination and adulteration of drug, chemical, or biological products. This thesis aims to develop a cleaning validation model specifically for a tablet production line, focusing on four key machines: the double cone blender, fluidized bed dryer, compression machine, and high-shear mixer. Cleaning Standard Operating Procedures (SOP) we

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Fatoki, Olalekan S., Beatrice O. Opeolu, Bettina Genthe, and Olatunde S. Olatunji. "Multi-residue method for the determination of selected veterinary pharmaceutical residues in surface water around Livestock Agricultural farms." Heliyon 4, no. 12 (2018): e01066. http://dx.doi.org/10.1016/j.heliyon.2018.e01066.

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