Relevant bibliographies by topics / Pharmaceutical technology

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pharmaceutical technology'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Pharmaceutical technology"

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Pegu, Lukesh, Pankaj Chasta, and Mr Kaushal K. Chandrul. "Pharmaceutical Packaging Technology." International Journal of Trend in Scientific Research and Development Volume-3, Issue-3 (April 30, 2019): 1747–54. http://dx.doi.org/10.31142/ijtsrd23527.

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Hollenbeck, R. Gary. "Pharmaceutical Technology: Tableting Technology." Journal of Pharmaceutical Sciences 78, no. 2 (February 1989): 182. http://dx.doi.org/10.1002/jps.2600780224.

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Sharma Meenu, Shivangi. "Pharmaceutical Supply Chain Using Blockchain Technology." International Journal of Science and Research (IJSR) 12, no. 6 (June 5, 2023): 899–902. http://dx.doi.org/10.21275/sr23606113214.

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Nasir, Fazli. "Welcome to Pharmaceutical Communications." Pharmaceutical Communications 1, no. 01 (December 31, 2022): 01. http://dx.doi.org/10.55627/pharma.001.001.0203.

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Welcome to the inaugural issue of Pharmaceutical Communications-a biannual, open access, and peer-reviewed journal aiming to publish high-quality research articles in the field of basic & advanced pharmaceutics and pharmaceutical technology. Pharmaceutical Communications is a biannual, peer-reviewed journal published online and in print that primarily publishes research articles and reviews that focus on basic and advanced pharmaceutics. The journal accepts manuscripts related to but not limited to, the processing of pharmaceuticals, such as crystallization, lyophilization, chemical stability of drugs, pharmacokinetics, biopharmaceutics, pro-drug developments, metabolic disposition of bioactive agents, dosage form design, pharmaceutical technology, targeted drug delivery. Other topics include pharmaceutical marketing, pharmaceutical promotion, patient-provider communication, healthcare communication, patient safety, and innovations in the pharmaceutical industry. Pharmaceutical Communications primarily accepts original research articles and reviews. However, invited editorial summaries and letters to the editor are also occasionally published. The journal provides a platform for scientists, practitioners, and healthcare professionals to share their knowledge and experiences in the field of pharmaceutics. The journal also serves as a forum for discussing and debating current issues and trends in the pharmaceutical industry. The journal welcomes submissions from academics, practitioners, and industry professionals who wish to share their research and perspectives on topics related to pharmaceutics. In the last two decades, rapid technological advances have enabled researchers to investigate arcane technological phenomena and ask more profound questions. Several pharmaceutical processes involved in the manufacturing of various dosage forms are being unraveled at a rapid pace, high resolution, and with unprecedented details. Authors carrying out investigations leveraging these technologies dealing with the composition, formulation, preparation, or manufacturing and quality control of extemporaneously compounded or commercially manufactured drugs are encouraged to submit their findings to Pharmaceutical Communications. The purpose of this journal is to provide a platform to the scientific fraternity, especially regional and national academics, where they could get their studies published after a rapid, transparent, and high-quality peer review. All the articles published in Pharmaceutical Communications will be freely available to readers immediately after publication. The open-access policy of our journal is likely to increase the readership of articles and enhance their visibility and citation potential. The journal also welcomes submissions from authors from any country. Therefore, I invite you to submit your work to Pharmaceutical Communications. We look forward to receiving your submissions! Professor Dr. Fazli Nasir Editor-In-Chief Rehabilitation Communications
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Banakar, Umesh V., and W. Wayne Young. "Pharmaceutical Technology Information." Journal of Pharmacy Technology 3, no. 4 (July 1987): 159–61. http://dx.doi.org/10.1177/875512258700300411.

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Wu, Chuan-Yu, Abderrahim Michrafy, Aleksander Mendyk, and Satoru Watano. "Pharmaceutical Particle Technology." Powder Technology 285 (November 2015): 1. http://dx.doi.org/10.1016/j.powtec.2015.09.014.

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Bodmeier, Roland. "Pharmaceutical Peiletizatlon Technology." Journal of Pharmaceutical Sciences 79, no. 7 (July 1990): 657. http://dx.doi.org/10.1002/jps.2600790727.

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Prozherina, Yuliya. "Technology and innovation in the pharmaceutical industry." Remedium. Journal about the Russian market of medicines and medical equipment, no. 1 (2021): 63–64. http://dx.doi.org/10.21518/1561-5936-2021-1-63-64.

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Analytics In recent years, technology and innovation have moved in leaps and bounds, changing all sectors including healthcare and pharmaceutics. The use of Big Data and process automation are driving rapid progress. The most modern approaches are being introduced into pharmacies and pharmaceutical enterprises even today.
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Pilpel, N. "Pharmaceutical technology. Tableting technology vol. 1." Endeavour 12, no. 3 (January 1988): 151. http://dx.doi.org/10.1016/0160-9327(88)90154-8.

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Vasudha, V., and A. R. Laiju. "A Sustainable Approach Towards Wastewater Treatment in Pharmaceutical Industry: A Review." IOP Conference Series: Earth and Environmental Science 1326, no. 1 (June 1, 2024): 012137. http://dx.doi.org/10.1088/1755-1315/1326/1/012137.

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Abstract Effluents from the pharmaceutical industry have become more concerned in recent years due to rising worries about the presence and management of pharmaceutical pollutants, raw materials, intermediates, and solvents. The pharmaceutical industry is one of the largest water consumers due to the many processes that require water. Different drug and pharmaceutical production methods result in wastewater containing a wide range of chemicals such as diclofenac, ibuprofen, carbamazepine, and clorfibric acid are commonly found in water and wastewater. As part of wastewater management, it is essential to analyse and design techniques for treating pharmaceutical wastewater in light of the limited available water resources. Furthermore, the industry mandates the reuse of water after impurities such as pharmaceuticals and other toxins. In our study, the main sources of wastewater in the pharmaceutical sector are identified, and the most effective removal technologies are examined and evaluated with the assistance of the study results. Bulk medications, pharmaceutically active substances, and other pharmaceuticals generate wastewater that utilizes much water. This effluent has been analyzed, and solutions for recovering valuable molecules to a considerable extent have been proposed. Finally, the treatment of wastewater has been addressed. Due to the shortcomings of traditional treatment techniques, the authors modified the conventional treatment procedure here using membrane bioreactors and cutting-edge techniques like ozonation, creating a hybrid wastewater treatment technology that may be a better alternative for treating pharmaceutical wastewater.
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Dissertations / Theses on the topic "Pharmaceutical technology"

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Barrett, Angela Mary Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Pharmaceutical processing using dense gas technology." Publisher:University of New South Wales. Chemical Sciences & Engineering, 2008. http://handle.unsw.edu.au/1959.4/41333.

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There exists a demand to re-engineer pre-existing pharmaceuticals to provide improved drug delivery, new dosage forms and increased drug safety and efficacy. Furthermore, the development of novel methods and formulations allows for the patent life of pre-existing drugs to be extended, which has obvious economic benefits for pharmaceutical companies. Dense gas technology provides a means to achieve these aims and to overcome the distinct limitations of traditional technologies. A novel formulation of the antifungal drug itraconazole has been developed using gas antisolvent processes. The new itraconazole-polymer formulation displayed a significant improvement in dissolution rate achieving 89.8 % dissolution compared to 52.5 % for the commercial formulation. The results of this study demonstrate the great opportunity to use dense gases for the creation of novel drug-polymer composite formulations with improved dissolution properties. The impregnation of an active ingredient into a polymer matrix is another method that can be used to improve the dissolution of poorly water soluble drugs. Dense gas technology has been incorporated into traditional methods for the formation of porous polymer matrices decreasing process residence times. However, some issues still need to be overcome including high operating temperatures and the use of class 3 solvents. A novel dense gas process for the formation of a porous polymer hydrogel matrix has been developed to improve upon current methodologies; Dense Gas Solvent Exchange Process (DGSEP). The Dense Gas Solvent Exchange Process was used to create a porous chitosan hydrogel impregnated with a stable amorphous form of the drug griseofulvin. Furthermore, the process was extended to include a hydrophilic polymer into the matrix. The resulting formulation had a dramatically improved dissolution rate achieving complete dissolution within 70 minutes compared with the commercial formulation which achieved less than 40 %dissolution in the same time. There is great potential for DGSEP to be applied to the formation of a variety of polymer hydrogels impregnated with active ingredients and incorporating polymers and other compounds. The significance of these results is that a simple and effective processing method has been developed to produce hydrogel systems that are suitable for the development of a diverse range of drug delivery systems.
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Peterson, Olga Yuris. "Transferring pharmaceutical batch technology to continuous flow." Thesis, Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/39510.

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The current trend in the pharmaceutical industry is towards continuous flow processes. Continuous flow reactor technology can produce a cheaper, better quality product at reduced energy and environmental cost through more efficient mass and heat transfer. It also enables a simplified and faster approach to bulk production by scaling out as opposed to scaling up. The research presented here focuses on the configuration and installation of a continuous flow system into the laboratory, and the transfer of a Meerwein-Ponndorf-Verley (MPV) reduction from batch to continuous mode. The Corning® glass continuous flow reactor in our laboratory utilizes specially-designed mixing structures for enhanced mass transfer. Additionally, the glass reactor offers nonreactivity and corrosion resistance over a wide range of temperature and pressure, which conventional steel reactors do not allow. The MPV reduction is a well-known method to prepare primary and secondary alcohols from aldehydes and ketones, respectively. The traditional MPV reduction protocol (Al(OiPr)₃ in isopropanol) was modified to enable the technological transfer from batch to continuous mode. This is the first time MPV reduction reactions were carried out in continuous mode. As a result, the MPV reduction of the model compound, benzaldehyde, was successfully conducted with 60% less catalyst and product yield was improved up to 20% (average of 10%) in continuous flow reactions as compared to current batch technology. These results are being used to develop a technology roadmap for the pharmaceutical industry to implement continuous flow processes in their manufacturing operations.
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Grobler, Anne Frederica. "Pharmaceutical applications of PheroidTM technology / Anne F. Grobler." Thesis, North-West University, 2009. http://hdl.handle.net/10394/6701.

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For a drug to have a therapeutic effect, it has to reach its site of action in sufficient quantities. The Pheroid drug delivery system enhances the absorption of drugs in various pharmacological categories and is the focus of this study. A number of patents are registered in various countries to protect its application. Pheroid technology is trademarked, but may for ease of reading, be called Pheroid(s) only. The Pheroid itself is composed of an organic carbon backbone composed of unsaturated fatty acids with some side-chain interactions that result in self-emulsifying characteristics. The resulting vesicles and nano-sponges can entrap hydrophilic, hydrophobic or amphiphilic compounds for biomedical and agricultural application and can be manipulated as to loading ability, mechanical resistance, permeability, size and solubility. Pheroid was investigated for its potential use in the areas of vaccines, peptide drugs, topical products and cosmeceuticals, antimicrobial treatments and agriculture. In all of these areas, the Pheroid has indeed shown applicability: the results showed improved uptake and/or efficacy of the entrapped chemical or biological compounds after administration by a number of administration routes. For oral administration, a precursor format, the pro-Pheroid, was used, wherein the vesicles and/or sponges are formed post-administration. Proof of concept studies on the in vivo absorption and bioavailability, as well as studies on in vitro efficacy of Pheroid-based formulations were carried out for antimicrobials, such as tuberculosis drugs, antimalarials and antiretrovirals. In all cases, the in vitro efficacy of the active compounds was increased, compared to well-known standard drug treatments. In a phase I bio-equivalence study, a Pheroid-containing combination formulation was compared against the comparative market leader. The results demonstrated that the bioavailability of the active compounds in the Pheroid was at least as good but mostly significantly better than that of the comparative medication. In addition, the incidence of side-effects was decreased in the case of the Pheroid formulations. Furthermore, in vitro results indicate that drug resistance can at least partially be negated. Pheroid technology may also be capable of protecting labile drugs such as peptides against degradation and increasing efficacy so that lower dosages can be administered less frequently and with fewer side effects. Based on in vitro and in vivo results, a number of products are currently in development. The application of Pheroid technology is potentially limitless and includes such areas as TB, malaria, cancer, AIDS, gene delivery, vaccines, patented medicines and generics and agriculture.
Thesis (Ph.D. (Pharmaceutics))--North-West University, Potchefstroom Campus, 2010.
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HAUSMAN-MANNING, DEBRA SUE. "APPLICATION OF PROCESS ANALYTICAL TECHNOLOGY TO PHARMACEUTICAL PROCESSES." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1108838053.

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Jadav, Niten B. "Novel Technology for Crystal Engineering of Pharmaceutical Solids." Thesis, University of Bradford, 2018. http://hdl.handle.net/10454/18177.

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The research work described in this thesis, the environmentally friendly novel "Microwave Assisted Sub-Critical water (MASCW)" technology for particle engineering of active pharmaceutical ingredients and excipients was developed. The present novel technology MASCW process is described as green technology as water is used as the solvent medium and microwave energy as external source of heat energy for generation of a particle with different morphological and chemical properties. In MASCW process supersaturated solution of APIs is prepared by dissolving solute in water at high temperature and pressure conditions. Upon rapid and controlled cooling, based on the aqueous solubility of solute, solute/solvent concentration and dielectric constant of water rapid precipitation of API with narrow particle size distribution occurs. Using paracetamol (pca) as API moiety understanding of the mechanism of MASCW crystallisation process was investigated. The effect of different process and experimental parameters on crystallisation pathway and end product attributes were analysed. Correlation between the degree of supersaturation concentration of pca solution against temperature and pressure parameters was explained by generating binary phase diagram. Determination of polymorphic transformation pathway of pca from form I (stable) to form II metastable polymorphs in solution was analysed using Raman spectroscopy. The difference between conventional heating and subcritical treatment was explored by determining the change in the solvent dielectric constant and solubility of hydrophobic API molecule. Based on the process understanding results, this technology was further implemented to explore its application in generating phase pure stable and metastable cocrystal phase. Based on the solubility of API and cocrystal former congruent (CBZ/SAC, SMT/SAC, SMZ/SAC) and incongruent (CAF/4HBA) cocrystal pairs were selected. For the first time generation of anhydrous phase of CAF: 4HBA cocrystal in 1:1 stoichiometric ration was reported and generation of metastable cocrystal phase of CA CBZ: SAC form II was reported. The application of this technology was explored in generating phase pure metastable polymorph of paracetamol which retain higher compressibility and dissolution rate. The potential of MASCW micronisation process, theophylline is used as the model component to produce micro sized particles for pulmonary drug delivery system via dry powder inhaler (Foradil inhaler). The results demonstrate that the THF particles generated using MASCW process displayed greater aerodynamic performance compared to conventional spray-dried THF sample. In the final chapter, synthesis of inorganic biomaterial (nano crystalline hydroxyapatite) was reported for the first time and the prospects of combining API like ibuprofen (IBU) with a biologically active component like nano-crystalline hydroxyapatite (HA) through hydrogen bonding was mechanistically explained using X-ray diffractometer and spectroscopic techniques.
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Calogerà, Giacomo <1976&gt. "An Investigation Into the Pharmaceutical Melt Granulation Technology." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2939/1/Caloger%C3%A0_Giacomo_tesi.pdf.

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Calogerà, Giacomo <1976&gt. "An Investigation Into the Pharmaceutical Melt Granulation Technology." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2939/.

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Yu, Shen. "Roll compaction of pharmaceutical excipients." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4137/.

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Roll compaction is commonly used as a dry granulation technique in the pharmaceutical industry to produce tablets for formulations sensitive to heat and moisture. This thesis reports systematic studies on the behavior of pharmaceutical excipients in associated unit operations (i.e. roll compaction, milling, tabletting), as well as their correlations. Roll compaction experiments were carried out using an instrumented roll compactor with a gravity feeding system. The influence of the process parameters, material properties and powder conditioning were investigated Ribbons produced in roll compaction were granulated using an oscillating mill to investigate the milling process. A first order kinetics equation was introduced to describe the mass throughput of the granules. Using positron emission particle tracking technique, which provided a measurement of instantaneous velocity and the location of the ribbons, two milling regions (i.e. impact and abrasion) involving distinct fracture mechanisms were identified. Tabletting of the granules was performed using a universal test machine. A reduction in the compressibility and compactibility of the granules compared to the feed powders, due to work hardening, was also observed. A method was introduced to determine the optimized process conditions for roll compaction and milling through a close examination of the correlation between the unit operations.
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Velaga, Sitaram P. "Preparation of Pharmaceutical Powders using Supercritical Fluid Technology : Pharmaceutical Applications and Physicochemical Characterisation of Powders." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4006.

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Mascia, Salvatore. "Rheology and processing of pharmaceutical pastes." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612373.

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Books on the topic "Pharmaceutical technology"

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Wells, James I. Pharmaceutical Technology. Hoboken: Informa Healthcare, 1991.

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1944-, Rubinstein M. H., and Wells James I. 1950-, eds. Pharmaceutical technology: Tableting technology. New York: Ellis Horwood, 1993.

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1944-, Rubinstein M. H., and Pharmaceutical Technology Conference (5th : 1986 : Harrogate, England), eds. Pharmaceutical technology--tableting technology. Chichester, West Sussex, England: Ellis Horwood, 1987.

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1934-, Cole Graham, Aulton Michael E, and Hogan John E, eds. Pharmaceutical coating technology. London: Taylor & Francis, 1995.

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Ghebre-Sellassie, Isaac. Pharmaceutical Pelletization Technology. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231.

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1947-, Ghebre-Sellassie Isaac, ed. Pharmaceutical pelletization technology. New York: M. Dekker, 1989.

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1923-, Dean D. A., Evans R, and Hall I, eds. Pharmaceutical packaging technology. London: Taylor & Francis, 2000.

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Ghebre-Sellassie, Isaac. Pharmaceutical Extrusion Technology. New York: Marcel Dekker, Inc., 2003.

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Hickey, Anthony J., and Sandro R. P. da Rocha, eds. Pharmaceutical Inhalation Aerosol Technology. Third edition. | Boca Raton, Florida : CRC Press, [2019] |: CRC Press, 2019. http://dx.doi.org/10.1201/9780429055201.

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1934-, Swarbrick James, and Boylan James C, eds. Encyclopaedia of pharmaceutical technology. New York: Dekker, 1997.

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Book chapters on the topic "Pharmaceutical technology"

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Fassbender, Birgit, and Timo Flessner. "Pharmaceutical research." In Technology Guide, 190–95. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-88546-7_37.

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Pouton, Colin W. "Stem Cell Technology." In Pharmaceutical Biotechnology, 509–24. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6486-0_25.

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Tamames-Tabar, C., A. García-Márquez, M. J. Blanco-Prieto, C. Serre, and P. Horcajada. "MOFs in Pharmaceutical Technology." In Bio- and Bioinspired Nanomaterials, 83–112. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527675821.ch04.

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O’Connor, Robert E., and Joseph B. Schwartz. "Extrusion and Spheronization Technology." In Pharmaceutical Pelletization Technology, 187–216. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-9.

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Mehta, Atul M. "Evaluation and Characterization of Pellets." In Pharmaceutical Pelletization Technology, 241–65. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-11.

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Harris, Michael R., and Isaac Ghebre-Sellassie. "Formulation Variables." In Pharmaceutical Pelletization Technology, 217–39. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-10.

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Hicks, Douglas C., and Howard L. Freese. "Extrusion and Spheronizing Equipment." In Pharmaceutical Pelletization Technology, 71–100. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-4.

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Chambliss, Walter G. "Conventional and Specialized Coating Pans." In Pharmaceutical Pelletization Technology, 15–38. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-2.

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Olsen, Kenneth W. "Fluid Bed Equipment." In Pharmaceutical Pelletization Technology, 39–69. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-3.

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Goodhart, Frank W., and Steve Jan. "Dry Powder Layering." In Pharmaceutical Pelletization Technology, 165–85. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003066231-8.

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Conference papers on the topic "Pharmaceutical technology"

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Thatcher, Camden, and Subrata Acharya. "Pharmaceutical uses of Blockchain Technology." In 2018 IEEE International Conference on Advanced Networks and Telecommunications Systems (ANTS). IEEE, 2018. http://dx.doi.org/10.1109/ants.2018.8710154.

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Benéitez, Maria Cristina, and Ángela Gómez. "PHARMACEUTICAL TECHNOLOGY INNOVATION LABORATORY PRACTICE." In INTCESS 2023- 10th International Conference on Education & Education of Social Sciences. International Organization Center of Academic Research, 2023. http://dx.doi.org/10.51508/intcess.202317.

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Khlebtsova, E. B., H. M. Bataev, and I. H. Baysultanov. "Pharmaceutical technology of Ortilia secunda." In I INTERNATIONAL CONFERENCE ASE-I - 2021: APPLIED SCIENCE AND ENGINEERING: ASE-I - 2021. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0076468.

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Terrado, Eva, and Elisa Langa. "PHARMACEUTICAL SCENE INVESTIGATION." In International Technology, Education and Development Conference. IATED, 2016. http://dx.doi.org/10.21125/iceri.2016.0478.

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Hamilton, Sara J., and Robert A. Lodder. "Hyperspectral imaging technology for pharmaceutical analysis." In International Symposium on Biomedical Optics, edited by Darryl J. Bornhop, David A. Dunn, Raymond P. Mariella, Jr., Catherine J. Murphy, Dan V. Nicolau, Shuming Nie, Michelle Palmer, and Ramesh Raghavachari. SPIE, 2002. http://dx.doi.org/10.1117/12.472076.

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Gil-Alegre, María Esther, Irene Teresa Molina-Martínez, María Dolores Veiga-Ochoa, María Del Rocío Herrero-Vanrell, Roberto Ruiz-Caro, Sergio Esteban-Pérez, José Javier López-Cano, David García-Herranz, Irene Bravo Osuna, and Vanessa Andrés-Guerrero. "CAN WE LEARN PHARMACEUTICAL TECHNOLOGY PLAYING?" In 14th International Technology, Education and Development Conference. IATED, 2020. http://dx.doi.org/10.21125/inted.2020.2448.

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Shammout, Hadi, Bence Sipos, Krisztina Ludasi, Selenay Belge, and Tamás Sovány. "Coating technology in the pharmaceutical industry." In VI. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Szeged: Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2024. http://dx.doi.org/10.14232/syrptbrs.2024.42.

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Yunfeng Lai and Hao Hu. "Crafting network competence for pharmaceutical innovation of Chinese pharmaceutical companies." In 2011 International Summer Conference of Asia Pacific Business Innovation and Technology Management (APBITM). IEEE, 2011. http://dx.doi.org/10.1109/apbitm.2011.5996294.

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Pathak, Agya, Sameer Shrivastava, Palempati Harsha Vardhini, Abhinay Meka, Divesh Swami, Zakir Hussain, and Malaya Dutta Borah. "Blockchain Technology in Pharmaceutical Supply Chain Management." In 2022 14th International Conference on Computational Intelligence and Communication Networks (CICN). IEEE, 2022. http://dx.doi.org/10.1109/cicn56167.2022.10008335.

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Ahmed, Yusra, and Tamás Sovány. "Fused deposition modelling (FDM) in pharmaceutical technology." In VI. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Szeged: Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2024. http://dx.doi.org/10.14232/syrptbrs.2024.52.

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Reports on the topic "Pharmaceutical technology"

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Arrow, Kenneth, Kamran Bilir, and Alan Sorensen. The Impact of Information Technology on the Diffusion of New Pharmaceuticals. Cambridge, MA: National Bureau of Economic Research, March 2017. http://dx.doi.org/10.3386/w23257.

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Kolodziejczyk, Bart. Emergence of Quantum Computing Technologies in Automotive Applications: Opportunities and Future Use Cases. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, April 2024. http://dx.doi.org/10.4271/epr2024008.

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<div class="section abstract"><div class="htmlview paragraph">Quantum computing and its applications are emerging rapidly, driving excitement and extensive interest across all industry sectors, from finance to pharmaceuticals. The automotive industry is no different. Quantum computing can bring significant advantages to the way we commute, whether through the development of new materials and catalysts using quantum chemistry or improved route optimization. Quantum computing may be as important as the invention of driverless vehicles.</div><div class="htmlview paragraph"><b>Emergence of Quantum Computing Technologies in Automotive Applications: Opportunities and Future Use Cases</b> attempts to explain quantum technology and its various advantages for the automotive industry. While many of the applications presented are still nascent, they may become mainstream in a decade or so.</div><div class="htmlview paragraph"><a href="https://www.sae.org/publications/edge-research-reports" target="_blank">Click here to access the full SAE EDGE</a><sup>TM</sup><a href="https://www.sae.org/publications/edge-research-reports" target="_blank"> Research Report portfolio.</a></div></div>
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Committee on Toxicology. COT FSA PBPK for Regulators Workshop Report 2021. Food Standards Agency, April 2024. http://dx.doi.org/10.46756/sci.fsa.tyy821.

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The future of food safety assessment in the UK depends on the Food Standards Agency’s (FSA) adaptability and flexibility in responding to and adopting the accelerating developments in science and technology. The Tox21 approach is an example of one recent advancement in the development of alternative toxicity testing approaches and computer modelling strategies for the evaluation of hazard and exposure (New Approach Methodologies (NAMs). A key aspect is the ability to link active concentrations in vitro to likely concentrations in vivo, for which physiologically based pharmacokinetic (PBPK) modelling is ideally suited. The UK FSA and the Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment (COT) held an “PBPK for Regulators” workshop with multidisciplinary participation, involving delegates from regulatory agencies, government bodies, academics, and industry. The workshop provided a platform to enable expert discussions on the application of PBPK to health risk assessment in a regulatory context. Presentations covered current application of PBPK modelling in the agrochemical industry for in vitro to in vivo extrapolation (IVIVE), pharmaceutical industry for drug absorption related issues (e.g., the effect of food on drug absorption) and drug-drug interaction studies, as well as dose extrapolations to special populations (e.g., those with a specific disease state, paediatric/geriatric age groups, and different ethnicities), environmental chemical risk assessment, an overview of the current regulatory guidance and a PBPK model run-through. This enabled attendees to consider the wide potential and fitness for purpose of the application of PBPK modelling in these fields. Attendees considered applicability in the context of future food safety assessment for refining exposure assessments of chemicals with narrow margins of exposure and/or to fill data gaps from more traditional approaches (i.e., data from animal testing). The overall conclusions from the workshop were as follows: PBPK modelling tools were applicable in the areas of use covered, and that expertise was available (though it is in small numbers). PBPK modelling offers opportunities to address questions for compounds that are otherwise not possible (e.g., considerations of human variability in kinetics) and allows identification of “at risk” subpopulations. The use of PBPK modelling tends to be applied on a case-by-case basis and there appears to be a barrier to widespread acceptance amongst regulatory bodies due to the lack of available in-house expertise (apart from some medical and environmental agencies such as the European Medicines Agency, United States Food and Drug Administration, and the US Environmental Protection Agency, respectively). Familiarisation and further training opportunities on the application of PBPK modelling using real world case studies would help in generating interest and developing more experts in the field, as well as furthering acceptance. In a regulatory context, establishing fitness for purpose for the use of PBPK models requires transparent discussion between regulatory agencies, government bodies, academics, and industry and the development of a harmonised guidance such as by the Organisation for Economic Co-operation and Development (OECD) would provide a starting point. Finally, PBPK modelling is part of the wider “new approach methodologies” for risk assessment, and there should be particular emphasis in modelling both toxicodynamics and toxicokinetics.
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