Relevant bibliographies by topics / Pharmacokinetics Drugs Drugs

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pharmacokinetics Drugs Drugs'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "Pharmacokinetics Drugs Drugs"

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Shikov, Alexander N., Elena V. Flisyuk, Ekaterina D. Obluchinskaya, and Olga N. Pozharitskaya. "Pharmacokinetics of Marine-Derived Drugs." Marine Drugs 18, no. 11 (2020): 557. http://dx.doi.org/10.3390/md18110557.

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Marine organisms represent an excellent source of innovative compounds that have the potential for the development of new drugs. The pharmacokinetics of marine drugs has attracted increasing interest in recent decades due to its effective and potential contribution to the selection of rational dosage recommendations and the optimal use of the therapeutic arsenal. In general, pharmacokinetics studies how drugs change after administration via the processes of absorption, distribution, metabolism, and excretion (ADME). This review provides a summary of the pharmacokinetics studies of marine-deriv
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Stepensky, David. "Pharmacokinetics of Toxin-Derived Peptide Drugs." Toxins 10, no. 11 (2018): 483. http://dx.doi.org/10.3390/toxins10110483.

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Toxins and venoms produced by different organisms contain peptides that have evolved to have highly selective and potent pharmacological effects on specific targets for protection and predation. Several toxin-derived peptides have become drugs and are used for the management of diabetes, hypertension, chronic pain, and other medical conditions. Despite the similarity in their composition (amino acids as the building blocks), toxin-derived peptide drugs have very profound differences in their structure and conformation, in their physicochemical properties (that affect solubility, stability, etc
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Scheyer, Richard, and Joyce Cramer. "Pharmacokinetics of Antiepileptic Drugs." Seminars in Neurology 10, no. 04 (1990): 414–21. http://dx.doi.org/10.1055/s-2008-1063986.

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LIPWORTH, BRIAN J. "Pharmacokinetics of inhaled drugs." British Journal of Clinical Pharmacology 42, no. 6 (1996): 697–705. http://dx.doi.org/10.1046/j.1365-2125.1996.00493.x.

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Browne, T. R. "Pharmacokinetics of antiepileptic drugs." Neurology 51, Issue 5, Supplement 4 (1998): S2—S7. http://dx.doi.org/10.1212/wnl.51.5_suppl_4.s2.

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McIlleron, Helen, and Hermien Gous. "Pharmacokinetics of antiretroviral drugs in infancy." Southern African Journal of HIV Medicine 10, no. 4 (2009): 54. http://dx.doi.org/10.4102/sajhivmed.v10i4.260.

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Infancy (from birth until 1 year of age) is a time of rapid changes within the body of a child. These changes affect pharmacokinetics in many ways. The CHER study1 showed that early antiretroviral treatment reduces mortality and disease progression amongst infants acquiring HIV infection before 12 weeks of age. As a result the World Health Organization has recently revised treatment initiation recommendations in children less than one year of age: all infants under 12 months of age with confirmed HIV infection should be started on antiretroviral therapy, irrespective of clinical or immunologic
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Ziółkowski, H., J. J. Jaroszewski, N. Ziółkowska, and A. Jasiecka. "Characteristics of selected second-generation antiepileptic drugs used in dogs." Polish Journal of Veterinary Sciences 15, no. 3 (2012): 571–82. http://dx.doi.org/10.2478/v10181-012-0088-1.

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Abstract A significant number of cases of clinical canine epilepsy remain difficult to control in spite of the applied treatment. At the same time, the range of antiepileptic drugs is increasingly wide, which allows efficient treatment. In the present paper we describe the pharmacodynamics and pharmacokinetics of the newer antiepileptic drugs which were licensed after 1990 but are still not widely used in veterinary medicine. The pharmacokinetic profiles of six of these drugs were tested on dogs. The results of experimental studies suggest that second generation antiepileptic drugs may be appl
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White, Nicholas J. "Clinical Pharmacokinetics of Antimalarial Drugs." Clinical Pharmacokinetics 10, no. 3 (1985): 187–215. http://dx.doi.org/10.2165/00003088-198510030-00001.

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Edwards, Geoffrey, and Alasdair M. Breckenridge. "Clinical Pharmacokinetics of Anthelmintic Drugs." Clinical Pharmacokinetics 15, no. 2 (1988): 64–93. http://dx.doi.org/10.2165/00003088-198815020-00001.

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Evans, William E., and Mary V. Relling. "Clinical Pharmacokinetics-Pharmacodynamicsof Anticancer Drugs." Clinical Pharmacokinetics 16, no. 6 (1989): 327–36. http://dx.doi.org/10.2165/00003088-198916060-00001.

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Dissertations / Theses on the topic "Pharmacokinetics Drugs Drugs"

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Chigutsa, Emmanuel. "Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs." Doctoral thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/3275.

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Includes abstract.<br>Includes bibliographical references.<br>The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in 78 patients with tuberculosis were described using non-linear mixed effects modeling. Pharmacodynamic data was comprised of weekly sputum liquid culture (using mycobacterial growth indicator tubes) time to detection results from 144 patients during the first 2 months of treatment. The effect of drug exposure on patient outcomes was investigated. To determine the adequacy of ofloxacin drug exposure, the probability of attaining the required area-under-the-c
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Olsén, Lena. "Drugs in horses : pharmacokinetics and pharmacodynamics /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/200737.pdf.

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Song, Di. "Bladder tissue pharmacokinetics of anticancer drugs /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487940308433249.

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Wang, Shining. "DRUG DEVELOPMENT OF TARGETED ANTICANCER DRUGS BASED ON PK/PD INVESTIGATIONS." Diss., Temple University Libraries, 2008. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/2535.

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Pharmaceutics<br>Ph.D.<br>EGFR inhibitors, such as gefitinib, are examples of targeted anticancer drugs whose drug sensitivity is related to gene mutations that adds a pharmacogenetic [PG] dimension to any pharmacokinetic [PK] and pharmacodynamic [PD] analysis. The goal of this project was to characterize the PK/PD properties of gefitinib in tumors and then apply these results to design rational drug design regimens, and provide a foundation for future studies with EGFR inhibitors. Progressions of in vitro and in vivo studies were completed to understand the PK and PD behavior of gefitinib. In
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James, Devona Gwen. "The degradation of drugs in formaldehyde." Morgantown, W. Va. : [West Virginia University Libraries], 1999. http://etd.wvu.edu/templates/showETD.cfm?recnum=1149.

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Thesis (M.S.)--West Virginia University, 1999.<br>Title from document title page. Document formatted into pages; contains xvi, 100 p. : ill. Vita. Includes abstract. Includes bibliographical references (p. 98-99).
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Yeh, Teng-Kuang. "Pharmacokinetics of anti-aids and anti-cancer drugs : implications on drug delivery and drug interaction /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu148654688938101.

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Mashile, Tumelo Rameleko. "Enantioanalysis of pharmaceutical compounds." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-02222007-195248.

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Reis, Margareta. "Pharmacokinetics of antidepressant drugs : naturalistic and clinical trials /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/med783s.pdf.

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Hammann, Felix. "Prediction of transport, pharmacokinetics, and effect of drugs /." Basel : [s.n.], 2009. http://edoc.unibas.ch/diss/DissB_8905.

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Zhang, Yuan. "The role of drug disposition genes for variability in the pharmacokinetics of antiretroviral drugs." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/9075/.

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The failure of highly active antiretroviral therapy may be due to pharmacological factors such as drug transporters and metabolism enzymes. Drug transporters and metabolism enzymes played complementary roles in drug absorption, distribution, metabolism and excretion by biotransformation and counter-transport, particularly in the intestine while nuclear receptors as transcription factors regulate the expression of drug transporters and metabolism enzymes. In this thesis, a positive correlation between nuclear receptors expression and the expression of ABC transporters and OATP transporters in i
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Books on the topic "Pharmacokinetics Drugs Drugs"

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Welling, Peter G., and Luc P. Balant, eds. Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8.

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1935-, Shader Richard I., ed. Pharmacokinetics in clinical practice. Saunders, 1985.

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Welling, Peter G. Pharmacokinetics of cardiovascular, central nervous system, and antimicrobial drugs. The Royal Society of Chemistry, 1985.

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Bourne, D. W. A. Pharmacokinetics for the non-mathematical. MTP Press, 1986.

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Smith, Dennis A. Pharmacokinetics and metabolism in drug design. Wiley-VCH, 2001.

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Gerontokinetics: Pharmacokinetics of drugs in the elderly and aged. Telford Press, 1988.

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Lees, Peter, Fiona M. Cunningham, and Elliott Jonathan. Comparative and veterinary pharmacology. Springer, 2010.

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Harvey, Wong, Hop, Cornelis E.C.A., and SpringerLink (Online service), eds. Drug Metabolism and Pharmacokinetics Quick Guide. Springer Science+Business Media, LLC, 2011.

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Craigmill, Arthur L. Handbook of comparative pharmacokinetics and residues of veterinary therapeutic drugs. CRC Press, 1994.

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Psychotropic drugs and the elderly. W.W. Norton, 2004.

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Book chapters on the topic "Pharmacokinetics Drugs Drugs"

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Dong, Hanqing, Xiaochuan Guo, and Zengbiao Li. "Pharmacokinetics of Chiral Drugs." In Chiral Drugs. John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118075647.ch9.

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Perucca, E., and A. Richens. "Clinical Pharmacokinetics of Antiepileptic Drugs." In Antiepileptic Drugs. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69518-6_24.

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Khojasteh, Siamak Cyrus, Harvey Wong, and Cornelis E. C. A. Hop. "Approved Drugs." In Drug Metabolism and Pharmacokinetics Quick Guide. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-5629-3_11.

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McMartin, C. "Peptide and Protein Drugs." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_13.

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Welling, P. G. "Role of Pharmacokinetics in Drug Discovery and Development." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_1.

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Pelkonen, O., and D. D. Breimer. "Role of Environmental Factors in the Pharmacokinetics of Drugs: Considerations with Respect to Animal Models, P-450 Enzymes, and Probe Drugs." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_10.

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Holford, N. H. G., and T. M. Ludden. "Time Course of Drug Effect." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_11.

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Ferraiolo, B. L., R. J. Wills, and M. A. Mohler. "Biotechnology Products." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_12.

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Kantrowitz, J., and A. Yacobi. "Toxicokinetics." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_14.

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Steimer, J. L., S. Vozeh, A. Racine-Poon, N. Holford, and R. O’Neill. "The Population Approach: Rationale, Methods, and Applications in Clinical Pharmacology and Drug Development." In Pharmacokinetics of Drugs. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78680-8_15.

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Conference papers on the topic "Pharmacokinetics Drugs Drugs"

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Lee, Jae-Hwan, and Ramana M. Pidaparti. "An Implantable Device Design Concept for Ocular Drug Delivery." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80176.

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New drugs for curing eye diseases have been developing for a decade and are very unique for each eye diseases such as glaucoma, cataracts, and age-related macular degeneration (AMD). It is estimated that 1.6 million adults in the US over the age of 50 and above suffer from age-related macular degeneration and about 200,000 cases are diagnosed annually. Worldwide, about 500,000 cases are diagnosed annually [1]. Drugs currently utilized for AMD are delivered via repeated intravitreal injections of the drug into the eye. Risks of repeated intravitreal injections can include intraocular infections
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Scherf-Clavel, M., L. Samanski, R. Burger, J. Deckert, A. Menke, and S. Unterecker. "Differences in the pharmacokinetics of psychopharmacological drugs between smokers and nonsmokers." In XIIIth Symposium of the Task Force Therapeutic Drug Monitoring of the AGNP. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1649541.

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Caron, Whitney P., Harvey Clewell, Robert Dedrick, et al. "Abstract 373: Allometric scaling of the pharmacokinetics of pegylated liposomal anticancer drugs." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-373.

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Shafahi, Maryam, and Parham Piroozan. "Model of Drug Delivery to the Eye." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-39438.

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Ocular diseases cause vision deficiency and blindness in a substantial number of people in the world every day. Therefore, a controlled and sustained system of drug delivery to a specific spot within the eye is of interest for the ophthalmology community. The unique and complicated anatomy, physiology, and biochemistry of the eye make this organ highly resistant to drug delivery systems. The major challenge is to improve the efficiency of each treatment method along with avoiding the invasive techniques which damage the eye’s protective barrier tissues. In this work we make a computer model fo
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Shimada, Takashi, Noriko Iwamoto, Sho Saeki, Ji-ichiro Sasaki, Taka-Aki Sato, and Akinobu Hamada. "Abstract 2962: Development of the LCMS bioanalysis for clinical pharmacokinetics of antibody drugs using Fab-selective limited proteolysis (nSMOL)." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2962.

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Tourlomousis, Filippos, and Robert C. Chang. "2D and 3D Multiscale Computational Modeling of Dynamic Microorgan Devices as Drug Screening Platforms." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52734.

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The ability to incorporate three-dimensional (3D) hepatocyte-laden hydrogel constructs using layered fabrication approaches into devices that can be perfused with drugs enables the creation of dynamic microorgan devices (DMDs) that offer an optimal analog of the in vivo liver metabolism scenario. The dynamic nature of such in vitro metabolism models demands reliable numerical tools to determine the optimum process, material, and geometric parameters for the most effective metabolic conversion of the perfused drug into the liver microenvironment. However, there is a current lack of literature t
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Sadiq, Muhammad Waqas, Olaf Holz, Birthe Ellinghusen, et al. "Late Breaking Abstract - Spatial pharmacokinetics of inhaled drugs in human lung – evaluation of regional lung targeting by direct sampling of epithelial lining fluid." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.oa2103.

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Teo, Ka Yaw, and Bumsoo Han. "Freezing-Assisted Intracellular Drug Delivery to Multi-Drug Resistant Cancer Cells." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192373.

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The efficacy of chemotherapy is significantly impaired by multi-drug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain ATP-binding cassette protein transporters in plasma membranes. These transporters actively keep intracellular drug concentration below the cell-killing threshold by extruding cytotoxic drugs. Various strategies to overcome MDR have been proposed and have shown promising results at the laboratory level. However, pharmacokinetic alteration of co-administered anticancer agents reduces their clinical effectiveness. This leads t
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Blanco, Elvin, Takafumi Sangai, Funda Meric-Bernstam, and Mauro Ferrari. "Chemotherapeutic Synergy Enhancement Through Micellar Nanotherapeutics." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13263.

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Current chemotherapeutic regimens involve the administration of a combination of agents with hopes of gaining synergistic cell-killing effects observed in vitro. However, drug synergy is rarely realized clinically given the different pharmacokinetic profiles of the drugs. Recent findings show that a combination of rapamycin and paclitaxel proves highly effective at hindering growth of tumors wherein the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway. Our objective was to fabricate a micellar nanotherapeutic platform capable of delivering a multitude of ag
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Evans, Conor L. "Pharmacokinetic and pharmacodynamic tomography." In Visualizing and Quantifying Drug Distribution in Tissue V, edited by Conor L. Evans and Kin Foong Chan. SPIE, 2021. http://dx.doi.org/10.1117/12.2587224.

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Reports on the topic "Pharmacokinetics Drugs Drugs"

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Johnson, Corey, Colton James, Sarah Traughber, and Charles Walker. Postoperative Nausea and Vomiting Implications in Neostigmine versus Sugammadex. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/con.dnp.2021.0005.

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Purpose/Background: Postoperative nausea and vomiting (PONV) is a frequent complaint in the postoperative period, which can delay discharge, result in readmission, and increase cost for patients and facilities. Inducing paralysis is common in anesthesia, as is utilizing the drugs neostigmine and sugammadex as reversal agents for non-depolarizing neuromuscular blockers. Many studies are available that compare these two drugs to determine if neostigmine increases the risk of PONV over sugammadex. Sugammadex has a more favorable pharmacologic profile and may improve patient outcomes by reducing P
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Soliman, Tarik, Laura Hales, and Dan Hall. Enhancing the Pharmacokinetic Profile of Protein-Based Drugs. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada607394.

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Noker, Patricia E. Preclinical Pharmacodynamic and Pharmacokinetic Studies of Investigational New Drugs. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ada307633.

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Noker, Patricia E. Preclinical Pharmacodynamic and Pharmacokinetic Studies of Investigational New Drugs. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada425594.

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Noker, Patricia. Preclinical Pharmacodynamic and Pharmacokinetic Studies of Investigational New Drugs. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada274309.

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Hawkins, David R. Determination of Drug Pharmacokinetics and Metabolic Profile. Volume 2. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada192428.

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Kamimori, Gary H. Effect of Time of Menstrual Cycle on Drug Pharmacokinetics and Pharmacodynamics. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada409105.

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