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Journal articles on the topic 'Pharmacological Investigation'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

RENUKA, JAIN, and ARORA REKHA. "Phytochemical and Pharmacological Investigation of Heliotropium ellipticum Ledeb." Journal of Indian Chemical Society Vol. 74, May 1997 (1997): 430–31. https://doi.org/10.5281/zenodo.5909098.

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Department of Chemistry, University of Rajasthan. Jaipur-302 004 <em>Manuscript received 31 October 1995. revised 18 January 1996, accepted 19 January 1996</em> Phytochemical and Pharmacological Investigation of <em>Heliotropium ellipticum</em> Ledeb.

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2

Jain, S. C., R. Jain, R. A. Sharma, and F. Capasso. "Pharmacological investigation of Cassia italica." Journal of Ethnopharmacology 58, no. 2 (1997): 135–42. http://dx.doi.org/10.1016/s0378-8741(97)00091-3.

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3

Zinovieva, M. L., N. V. Kurdil, P. G. Zhminko, M. G. Prodanchuk, O. P. Kravchuk, and M. V. Velychko. "Pharmacological therapeutic appliance for acute poisoning by organophosphorous compounds of anticholinesterase action (review of literature)." Ukrainian Journal of Modern Toxicological Aspects 94, no. 1 (2023): 42–54. http://dx.doi.org/10.33273/2663-4570-2023-94-1-42-54.

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The current standards of treatment the acute OPC poisoning with anticholinesterase action remain insufficient, despite the significant number of researches in this area conducted in the world. One of the ways to solve this problem is to use a wider range of pathogenetically determined pharmacologic agents. The Aim of the Research. To observe and summarize the published results of investigation the pharmacological therapeutic appliance for acute OPC poisoning at the stages of preclinical and early clinical evaluation. Methods. System content analysis of literature data using the PubMed and Goog

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Siddiqui, AA, SM Wani, R. Rajesh, and V. Alagarsamy. "Phytochemical and pharmacological investigation ofHibiscus rosasinensislinn." Indian Journal of Pharmaceutical Sciences 68, no. 5 (2006): 588. http://dx.doi.org/10.4103/0250-474x.29625.

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Lakshmikanth, Dr P. "Phytonutrients Investigation and Pharmacological Activity of Plumbago Zeylanica L -An Overview." International Journal of Research Publication and Reviews 4, no. 12 (2023): 524–29. http://dx.doi.org/10.55248/gengpi.4.1223.123317.

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6

MATSUI, Kyoko, and Kazuya ANDO. "Behavioral Pharmacological Investigation of Wriggle Mouse Sagami." Experimental Animals 37, no. 1 (1988): 81–83. http://dx.doi.org/10.1538/expanim1978.37.1_81.

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7

Rádis-Baptista, Gandhi, and Katsuhiro Konno. "Toxinologic and Pharmacological Investigation of Venomous Arthropods." Toxins 14, no. 4 (2022): 283. http://dx.doi.org/10.3390/toxins14040283.

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8

Zvejniece, Liga, Baiba Svalbe, Grigory Veinberg, et al. "Investigation into Stereoselective Pharmacological Activity of Phenotropil." Basic & Clinical Pharmacology & Toxicology 109, no. 5 (2011): 407–12. http://dx.doi.org/10.1111/j.1742-7843.2011.00742.x.

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Nielsen, M. Lykkegaard, H. Laursen, J. Gauguin, and P. Rosenkast. "Doxycyclinum NFN: A Pharmacological and Bacteriological Investigation." Acta Pharmacologica et Toxicologica 29, no. 2-3 (2009): 314–26. http://dx.doi.org/10.1111/j.1600-0773.1971.tb00593.x.

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10

Chandrashekar, K. "Phytochemical and pharmacological investigation of Moringa oleifera." European Journal of Pharmacology 668 (September 2011): e37. http://dx.doi.org/10.1016/j.ejphar.2011.09.280.

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11

Aziba, P. I., D. Bass, and Y. Elegbe. "Pharmacological investigation of Ocimum gratissimum in rodents." Phytotherapy Research 13, no. 5 (1999): 427–29. http://dx.doi.org/10.1002/(sici)1099-1573(199908/09)13:5<427::aid-ptr467>3.0.co;2-t.

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Amici, Marco De, Clelia Dallanoce, Carlo De Micheli, et al. "Synthesis and pharmacological investigation of stereoisomeric muscarines." Chirality 4, no. 4 (1992): 230–39. http://dx.doi.org/10.1002/chir.530040406.

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13

Rehman, Bushra, Aiman Umer, Muhammad Kashif Aman, Hajra Afeera Hamid, Danish Iqbal, and Sanam Islam Khan. "Phytochemical and Pharmacological Investigation of Lespedesea Gerardiana." Fall 2023 VIII, no. IV (2023): 23–33. http://dx.doi.org/10.31703/gdddr.2023(viii-iv).03.

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The World Health Organization (WHO) is giving more prominence to promoting traditional medicine, particularly, in thirdâworld countries. The global market of medicinal plants is estimated at over US$ 60.0 billion which is expected to grow up to US$ 5.0 trillion by the year 2050. In Pakistan, the bill for the import of medicinal plants was worth US$ 31.0 million, whereas the export of medicinal plants could hardly reach US$ 6.0 million. In the world, 30% of the pharmaceutical preparations are manufactured from plants. Keeping in view the potential of the global and local market, we conducted

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Bhuiyan, Md Anik, Hasib Khan Shomudro, and Sadia Afreen Chowdhury. "In-vitro Pharmacological Investigation of Ludwigia adscendens." Asian Plant Research Journal 11, no. 6 (2023): 44–55. http://dx.doi.org/10.9734/aprj/2023/v11i6229.

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Aims: This research objective was to investigate some in-vitro properties of methanol-extracted plant extracts of Ludwigia adscendens (the water primrose). The primary method of assessment for the methanolic extract of Ludwigia adscendens (MELA) was investigated for phytochemical screening. It was determined to look into the plant's potential for in vitro activities, such as antioxidant, antimicrobial, anti-inflammatory anti-arthritis, cytotoxic, thrombolytic and membrane stabilizing activity due to the pharmaceutical interest in its component parts. Methodology: Phytochemical screening

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15

Pal, Netra, Suraj Mandal, Km Shiva, and Bijender Kumar. "Pharmacognostical, Phytochemical and Pharmacological Evaluation of Mallotus philippensis." Journal of Drug Delivery and Therapeutics 12, no. 5 (2022): 175–81. http://dx.doi.org/10.22270/jddt.v12i5.5675.

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The present study was aimed at Pharmacognostical, Phytochemical and Pharmacological evaluation of the plant Mallotus Philippinensis family- Euphorbiaceae. Pharmacognostical investigation were carried out by performing organoleptic, microscopical and physicochemical evaluation i.e. ash values, extractive values, moisture content, swelling index, foaming index and foreign matter. The obtained results showed that the moisture content was found to be 1.74%. Similarly swelling index was recorded to be (0.8cm). Foaming index (less than 100). Phytochemical investigation included successive soxhlet ex

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Nourmohammadi, Jalal, Mohsen Akhondi, Fereshte Rajabiniat, Zahra S. H. Vaeaz, Zahra Nourmohammadi, and Mahdieh H. Moghadam. "Pharmacological evaluation of glomerulonephritis in Covid-19 patients." Romanian Journal of Military Medicine 125, no. 4 (2022): 630–35. http://dx.doi.org/10.55453/rjmm.2022.125.4.14.

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"Acute kidney injury (AKI) and glomerulonephritis can be complications in COVID-19 patients, which is announced with widely incidence rates in different investigations and is determined to have a major effect on the prognosis of the disease. There are considerable variations in AKI and glomerulonephritis rates between other countries. The rate is generally lower than in Western Europe and the United States in China. Heterogeneity in different racial and ethnic lines can be a potential explanation. This investigation systematically reviews the scientific resources regarding AKI and glomerulonep

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Kumar, Suresh, Rajiv Dahiya, Sukhbir Khokra, Rita Mourya, Suresh Chennupati, and Sandeep Maharaj. "Total Synthesis and Pharmacological Investigation of Cordyheptapeptide A." Molecules 22, no. 6 (2017): 682. http://dx.doi.org/10.3390/molecules22060682.

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18

Zulfiker, AHM, MA Hoque, T. Akter, A. Afroz, and AM Momin. "Pharmacological investigation of selected medicinal plants of Bangladesh." Tropical Journal of Pharmaceutical Research 13, no. 11 (2014): 1925. http://dx.doi.org/10.4314/tjpr.v13i11.22.

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19

Rajapara, Aruna M., Vijay P. Bhatt, and Mamta B. Shah. "Phytochemical and Pharmacological Investigation on Onosma bracteatum Wall." Asian Journal of Biological and Life Sciences 10, no. 1 (2021): 141–49. http://dx.doi.org/10.5530/ajbls.2021.10.21.

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20

Sharma, Chandrachud, Yuvraj singh Sarangdevot, and Bhupendra Vyas. "Phytochemical investigation and Pharmacological screening of polyherbal preparation." Asian Journal of Pharmaceutical Research and Development 12, no. 3 (2024): 267–72. http://dx.doi.org/10.22270/ajprd.v12i3.1332.

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The present paper deals with the investigation on comparative physico-chemical and phytochemical screening of five medicinal plants viz., leaves of Gymnema sylvestre, fruits of Momordica charantia, rhizomes of Curcuma longa, seeds of Eugenia jambolana and fruits of Embilica officinalis widely used in the treatment of diabetes. In the present communication comparative results were shown. Various macroscopic, physicochemical and phytochemicals parameters were analyzed and were presented.

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Kozioł, Ewelina, and Krystyna Skalicka-Woźniak. "Imperatorin–pharmacological meaning and analytical clues: profound investigation." Phytochemistry Reviews 15, no. 4 (2016): 627–49. http://dx.doi.org/10.1007/s11101-016-9456-2.

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22

Grandhi, Anuradha, A. M. Mujumdar, and Bhushan Patwardhan. "A comparative pharmacological investigation of Ashwagandha and Ginseng." Journal of Ethnopharmacology 44, no. 3 (1994): 131–35. http://dx.doi.org/10.1016/0378-8741(94)01119-2.

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23

Yilmazer, Buge, Z. Begum Yagci, Emre Bakar, Burcu Ozden, Kutlu Ulgen, and Elif Ozkirimli. "Investigation of novel pharmacological chaperones for Gaucher Disease." Journal of Molecular Graphics and Modelling 76 (September 2017): 364–78. http://dx.doi.org/10.1016/j.jmgm.2017.07.014.

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24

Sonwane, Gajanan, Sujat Bhagat, Vijay Borkar, Shirish Jain, Sharuk khan, and Mayura Kale. "Pharmacological Activity Investigation of Alkaline Water – A Review." International Journal of Pharmaceutical Sciences Review and Research 64, no. 1 (2020): 88–91. http://dx.doi.org/10.47583/ijpsrr.2020.v64i01.017.

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25

Li, Zhi, Jian-Yu Mao, Xiao-Hui Zhou, and Zhen-Dong Xu. "Network Pharmacological Investigation of Sinomenine Action Against Synovitis." International Journal of Pharmacology 18, no. 8 (2022): 1550–59. http://dx.doi.org/10.3923/ijp.2022.1550.1559.

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26

De Micheli, C., M. De Amici, G. Marucci, and F. Paparelli. "Synthesis and pharmacological investigation of chiral stereoisomeric difluoromuscarines." Life Sciences 56, no. 11-12 (1995): 1012. http://dx.doi.org/10.1016/0024-3205(95)93736-x.

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27

C.V. Nagathan, Shivanand Kolageri, and Suresh Gunaki. "Phytochemical and pharmacological investigation of Crinum solapurense Lam." World Journal of Advanced Research and Reviews 18, no. 2 (2023): 1181–91. http://dx.doi.org/10.30574/wjarr.2023.18.2.0954.

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The widely used indigenous medicinal plant Crinum solapurense Lam is the subject of the current inquiry. According to the study and pertinent literature, the plant Crinum solapurense Lam. It is most well-known for its use in traditional medicines, while different portions of the plant have received less attention. The current research program aims to assess the phytochemical analysis and antioxidant, anthelmintic efficacy of Crinum solapurense bulb ethanolic extract with the following objectives: authentication and storage of plant materials, successive extraction of different solvents from po

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C.V., Nagathan, Kolageri Shivanand, and Gunaki Suresh. "Phytochemical and pharmacological investigation of Crinum solapurense Lam." World Journal of Advanced Research and Reviews 18, no. 2 (2023): 1181–91. https://doi.org/10.5281/zenodo.8414161.

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The widely used indigenous medicinal plant <em>Crinum solapurense </em>Lam is the subject of the current inquiry. According to the study and pertinent literature, the plant <em>Crinum solapurense </em>Lam. It is most well-known for its use in traditional medicines, while different portions of the plant have received less attention. The current research program aims to assess the phytochemical analysis and antioxidant, anthelmintic efficacy of <em>Crinum solapurense </em>bulb ethanolic extract with the following objectives: authentication and storage of plant mater

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29

Dávid, Csilla Zsuzsanna, Judit Hohmann, and Andrea Vasas. "Chemistry and Pharmacology of Cyperaceae Stilbenoids: A Review." Molecules 26, no. 9 (2021): 2794. http://dx.doi.org/10.3390/molecules26092794.

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Cyperaceae is a cosmopolitan plant family with approx. 5000 species distributed worldwide. Several members of this family are used in traditional medicines for the treatment of different diseases. In the last few decades, constituents with great chemical diversity were isolated from sedges, and a wide range of biological activities were detected either for crude extracts or for pure compounds. Among the isolated compounds, phenolic derivatives are the most important, especially stilbenoids, and flavonoids. To date, more than 60 stilbenoids were isolated from 28 Cyperaceae species. Pharmacologi

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30

Zeenath Khan, M. Madhavi Latha, K. Narendra, G. Sneha latha, K. Babu, and K. Mallikarjuna. "Pharmacological evaluation of rice varieties, Hassawi and Njavara." International Journal of Science and Research Archive 13, no. 2 (2024): 959–69. http://dx.doi.org/10.30574/ijsra.2024.13.2.2110.

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Hasswai and Njavara are two notable international and Indian red rice cultivars that provide a variety of nutrients and phytochemicals. An effort was made to investigate the pharmacological properties of these rice types. In conclusion, both types of rice exhibit lipid peroxidation, acetylcholinesterase, thrombolytic, anti-arthritic, antioxidant, and anti-inflammatory properties. Methanol extracts showed increased acetylcholinesterase, thrombolytic, and antioxidant activity in the current investigation. On the other hand, aqueous extracts have stronger anti-inflammatory, anti-arthritic, lipid

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31

Ilic, Dusica, Vesna Nikolic, Ljubisa Nikolic, Mihajlo Stankovic, Ljiljana Stanojevic, and Milorad Cakic. "Allicin and related compounds: Biosynthesis, synthesis and pharmacological activity." Facta universitatis - series: Physics, Chemistry and Technology 9, no. 1 (2011): 9–20. http://dx.doi.org/10.2298/fupct1101009i.

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In this review, the biosynthesis of allicin (allyl thiosulfinate) by enzymatic transformation of alliin and various methods of its synthesis with detailed investigation of mechanisms and kinetics are summarized. A convenient method is also described for determination of allicin stability and the utility of the inclusion complexes of this pharmacologically active agent with ?-cyclodextrins in increasing its stability. Allicin is the initial precursor for the production of ajoene ((E)- and (Z)-4,5,9-trithiadodeca- 1,6,11-triene 9-oxides) and vinyldithiin (2-vinyl-4H-1,3-dithiin, and 3-vinyl-4H-1

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32

WASIULLAH, W., Saleem JAN, A. A. SHAD, A. BASIT, and F. ULLAH. "PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL ACTIVITIES OF HELIOTROPIUM CURASSAVICUM LINN." Latin American Applied Research - An international journal 49, no. 2 (2019): 105–9. http://dx.doi.org/10.52292/j.laar.2019.369.

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The current study was focused on the phytochemical investigation and pharmacological activities of the various fractions (methanolic crude, defatted methanolic, n-hexane, dichloromethane, ethylacetate and water) of H. curassavicum. The various plant extracts were examined for the total phenolic contents by taking Gallic acid as a standard, antioxidant scavenging assay by using DPPH (2, 2diphenyl-1-picrylhydrazy) & ABTS [2, 2-azinobis (3ethylbenzthiazoline-6-sulphonic acid)] free radicals, antifungal assay by using Terbinafine solution in DMSO as positive control and pure DMSO as negative c

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Islam, Md Mazharul, Mohammed Ibrahim, Mohiminul Adib, Syed Mohammed Tareq, Mohammad Rashedul Haque, and Mohammad A. Rashid. "Pharmacological Investigation on Ethanol Extract of Scindapsus hederaceus Miq." Bangladesh Pharmaceutical Journal 20, no. 1 (2017): 85–89. http://dx.doi.org/10.3329/bpj.v20i1.32097.

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The present study was conducted to evaluate the antipyretic, anti-inflammatory and membrane stabilizing, antioxidant, thrombolytic, anti-diarrheal activities of Scindapsu shederaceus belonging to the Araceae family. In antipyretic test, temperature reduced from 101.53°F to 99.86°F (p<0.05), 99.20°F (p<0.05) and 99.06°F (p<0.05) in 1st, 2nd and 3rd hour, respectively and caused maximum reduction of temperature in 1st hour. In the hot plate method, the extract increased the reaction time of heat sensation significantly to 14.32 seconds. In in vitro anti-inflammatory test, the extract si

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34

KUROKI, Y. "Investigation of Bioequivalency by Comparing Pharmacological Effect of Drugs." Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 29, no. 1/2 (1998): 297–98. http://dx.doi.org/10.3999/jscpt.29.297.

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35

Hammadi, Reham, Norbert Kúsz, Peter W. Mwangi, et al. "Isolation and Pharmacological Investigation of Compounds From Euphorbia matabelensis." Natural Product Communications 14, no. 7 (2019): 1934578X1986350. http://dx.doi.org/10.1177/1934578x19863509.

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This work deals with the isolation and pharmacological investigations of compounds of Euphorbia matabelensis. After multiple separation process, including thin layer chromatography (TLC), vacuum liquid chromatography, preparative TLC, and high-performance liquid chromatography, 1 diterpene (ingenol) and 2 flavonoids (naringenin and eriodictyol) were obtained from the methanol extracts prepared from the stems and roots of the plant. The structures of the isolated compounds were determined by nuclear magnetic resonance (NMR) and MS measurements and comparison with literature data. All compounds

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Falgairolle, Melanie, and Michael J. O’Donovan. "Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons." PLOS ONE 10, no. 6 (2015): e0131430. http://dx.doi.org/10.1371/journal.pone.0131430.

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37

Quaglia, M. G., E. Bossù, G. C. Porretta, et al. "Chromatographic resolution and pharmacological investigation of some imidazole derivatives." Journal of Chromatography A 729, no. 1-2 (1996): 1–4. http://dx.doi.org/10.1016/0021-9673(95)01347-4.

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38

Guantai, A., I. Addae-Mensah, and Gichuru Muriuki. "A Pharmacological Investigation of the Hypoglycemic Activity ofArtemisia afra." Planta Medica 55, no. 01 (1989): 94. http://dx.doi.org/10.1055/s-2006-961843.

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Shankar Thakre, Ms Minal, Mr Ganesh Ajabrao Sabe, and Mr Naved Khan. "A Review on Phytochemical Investigation of Gymnosporia Montana Benth to Treat Various Diseases." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 924–31. https://doi.org/10.35629/4494-0906924931.

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Gymnosporia montana is a plant that has been used for its therapeutic qualities in traditional medicine. The purpose of this study was to examine G. montana's phytochemical makeup, pharmacological properties, and ethnobotanical importance. Techniques: - Phytochemical analysis: NMR spectroscopy, GC-MS, and HPLC Pharmacological assessment: cytotoxicity, antimicrobial, antioxidant, and anti-inflammatory tests Ethnobotanical research: Community surveys and interviews Findings: - Flavonoids, alkaloids, and terpenoids were identified as bioactive chemicals. Pharmacological activity that have been de

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40

Varpe, Tanmay Ghogare Prajwal Gholve Gayatri Gore Aarti Jondhale Tejal*. "Passiflora Edulis: Phytochemical Analysis and Pharmacological Aspects." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1690–98. https://doi.org/10.5281/zenodo.15208911.

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The passion fruit, Passiflora edulis, has a variety of pharmacological properties. The rationale for this plant's use as a home remedy is its therapeutic qualities. Among Passiflora edulis, the Passifloraceae is the largest family. Passion Fruits are utilized as a variety of items. The entire plant, including the fruits, has many medicinal properties, including anti-inflammatory, anti-tumor, anti-tumor, analgesic, and antioxidant properties. Numerous useful chemical constituents are also present, including volatile oil, flavonoids, lipids, triterpenoids, aldehydes, ketones, tridecanone, palmit

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Ajay Philip, Ajay Philip, Angel Mosses, Christy Sebastian, Liya Mary NJ, Mathew George, and Lincy Joseph. "Phytochemical Investigation on Murraya Koenigiileaves." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 458–62. https://doi.org/10.35629/4494-0906458462.

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Murraya koenigii a staple spice in Indian cuisine, possess remarkable phytochemical and pharmacological properties. Its leaves are collected and dried. Authenticated the leaves. Dried leaves are extracted with alcohol and water in Soxhlet extractor. The extract subjected to various phytochemical tests. Carbohydrates, Protein, Glycosides, Flavanoids, Alkaloids, Tannins, Phenolic compounds andTerpenoids are found to be present in Murraya koenigii leaves

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Ashish, Kumar Yadav* Abhishek Yadav Ramesh Chandra. "Phytochemistry, Pharmacological Potential, And Traditional Uses of Asparagus Racemosus: A Comprehensive Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1933–45. https://doi.org/10.5281/zenodo.15056415.

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Asparagus racemosus (Shatavari) is a widely used medicinal plant known for its adaptogenic, immunomodulatory, anti-inflammatory, antioxidant, antimicrobial, and gastroprotective properties. It belongs to the family Asparagaceae and is rich in bioactive compounds, including steroidal saponins (shatavarins), flavonoids, alkaloids, and polysaccharides, which contribute to its therapeutic potential. This review provides a detailed overview of Asparagus racemosus, including its botanical description, pharmacognostical studies, phytochemical profile, physicochemical analysis, chromatographic techniq

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Stambolov, Ivan, Aleksandar Shkondrov, and Ilina Krasteva. "Astragalus glycyphyllos L.: Phytochemical constituents, pharmacology, and biotechnology." Pharmacia 70, no. 3 (2023): 635–41. http://dx.doi.org/10.3897/pharmacia.70.e107989.

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Astragalus glycyphyllos is a widely distributed plant found in Bulgaria that has been used in the folk medicine of the country for decades as an antihypertensive, diuretic, and anti-inflammatory. This review article is focused on the traditional usage, phytochemical studies, pharmacological activity, and biotechnology of this species. Recent progress in the phytochemical investigation led to the identification of different flavonoids, triterpenoid saponins, sterols, volatiles, etc. Many pharmacological studies, performed on extracts and pure compounds, revealed promising antiproliferative, cyt

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Jabbar, Ahmed Aj, Fuad O. Abdullah, Abdullah Othman Hassan, et al. "Ethnobotanical, Phytochemistry, and Pharmacological Activity of Onosma (Boraginaceae): An Updated Review." Molecules 27, no. 24 (2022): 8687. http://dx.doi.org/10.3390/molecules27248687.

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The genus Onosma belongs to the Boraginaceae family and contains over 230 species. The present review sheds light on the ethnopharmacology, phytoconstituents, bioactivity, and toxicology of the Onosma species from previous investigations. Furthermore, the paper also highlights the unresolved issues for the future investigations. The review included previous studies of the genus Onosma available from Google Scholar and Baidu Scholar, Science Direct, SciFinder, Wiley Online Library, and Web of Science. Until now, more than 200 chemical compounds have been detected from the genus Onosma, includin

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Aralova, N. I. "MATHEMATICAL MODEL FOR THE INVESTIGATION OF HYPOXIC STATES IN THE HEART MUSCLE AT VIRAL DAMAGE." Biotechnologia Acta 14, no. 4 (2021): 38–52. http://dx.doi.org/10.15407/biotech14.04.038.

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The main complications of organism damaged by SARS-CoV-2 virus are various cardiovascular system lesions. As a result, the secondary tissue hypoxia is developed and it is relevant to search the means for hypoxic state alleviation. Mathematical modeling of this process, followed by the imitation of hypoxic states development, and subsequent correction of hypoxia at this model may be one of the directions for investigations. Aim. The purpose of this study was to construct mathematical models of functional respiratory and blood circulatory systems to simulate the partial occlusion of blood vessel

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Yin, Zhenhua, Juanjuan Zhang, Qingfeng Guo, Lin Chen, Wei Zhang, and Wenyi Kang. "Pharmacological Effects of Verticine: Current Status." Evidence-Based Complementary and Alternative Medicine 2019 (March 7, 2019): 1–8. http://dx.doi.org/10.1155/2019/2394605.

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Verticine is the major bioactive constituent of Fritillaria as a kind of Traditional Chinese Medicine. Pharmacological researches have reported various benefits of verticine, including anticancer, anti-inflammatory, protecting against acute lung injury, tracheobronchial relaxation, antitussive, expectorant, sedative, and analgesic activities, in addition to inhibiting proliferation of cultured orbital fibroblast, angiotensin converting enzyme (ACE), and acetylcholinesterase (AChE) and inhibiting hERG potassium channels. The underlying mechanisms of verticine are still under investigation. This

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Verma, Kapil Kumar, Bhopesh Kumar, Hans Raj, and Akanksha Sharma. "A Review on Chemical Constituents, Traditional Uses, Pharmacological Studies of Zanthoxylum armatum (Rutaceae)." Journal of Drug Delivery and Therapeutics 11, no. 2-S (2021): 136–42. http://dx.doi.org/10.22270/jddt.v11i2-s.4786.

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Zanthoxylum armatum used as a medicine from ancient time for cure of various diseases such as toothache and problems related to tooth, asthma, used for gum bleeding, fever, dyspepsia, and tonics etc. Phytochemistry, pharmacological activities, diseases, traditional uses etc are explained in this review article .This article have information of the Z. armatum which may have Phytochemistry, pharmacological activities, diseases, traditional uses etc. Some latest info of Phytochemistry, pharmacological activities, diseases, traditional uses may show clearance in review. Different activities of var

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Ali Esmail Al-Snafi. "Medicinal plants with hypoglycemic effect: A review." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 147–73. http://dx.doi.org/10.30574/gscbps.2023.24.1.0274.

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Diabetes mellitus is one of the most common endocrine diseases. Due to its complications, it caused significant mortality. Insulin and oral antidiabetic drugs were associated with many side effects. The search for more effective and safer hypoglycemic agents is one of the important areas of investigation. The pharmacological investigations revealed that several medicinal plants showed hypoglycemic effects by many mechanisms. The current review highlighted the medicinal plants with antidiabetic effect.

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Ali, Esmail Al-Snafi. "Medicinal plants with hypoglycemic effect: A review." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 147–73. https://doi.org/10.5281/zenodo.8265215.

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Abstract:

Diabetes mellitus is one of the most common endocrine diseases. Due to its complications, it caused significant mortality. Insulin and oral antidiabetic drugs were associated with many side effects. The search for more effective and safer hypoglycemic agents is one of the important areas of investigation. The pharmacological investigations revealed that several medicinal plants showed hypoglycemic effects by many mechanisms. The current review highlighted the medicinal plants with antidiabetic effect.

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Schupp, Jonas, Björn Frye, Gernot Zissel, and Joachim Müller-Quernheim. "Sarcoidosis: Drugs under Investigation." Seminars in Respiratory and Critical Care Medicine 38, no. 04 (2017): 532–37. http://dx.doi.org/10.1055/s-0037-1603768.

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AbstractEtiology of sarcoidosis is still elusive, yet there has been considerable progress in various areas of basic and clinical research. In this review, we focus on ongoing or recently completed clinical–pharmacological studies in patients with sarcoidosis. Positive studies were published in well-characterized and homogenous subcohorts of sarcoid patients. Several drugs have shown a positive effect on sarcoidosis-associated fatigue, cutaneous sarcoidosis, and pulmonary hypertension in sarcoid patients. It seems that the recruitment of clinically precisely defined subcohorts is necessary to

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