Academic literature on the topic 'Pharmacology of antidepressants'

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Journal articles on the topic "Pharmacology of antidepressants"

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Dugan, Daniel J. "Antidepressants: Using Pharmacology to Individualize Therapy." Journal of Pharmacy Practice 14, no. 6 (2001): 458–66. http://dx.doi.org/10.1177/089719001129040955.

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The pharmacotherapy of depression has undergone significant change in the last two decades. A new generation of antidepressant agents has displaced older drugs as first-line therapies for depression. The clinician that seeks optimal outcomes for treatment of depression must be familiar with all of the available antidepressant agents. This article will discuss the pharmacologic profile of antidepressants currently marketed in the United States, identifying similarities and differences that have clinical relevance in the management of depression. Drug selection with an emphasis on antidepressant
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Jackson, Cherry W. "Antidepressants in the Treatment of Chronic Pain." Journal of Pharmacy Practice 11, no. 5 (1998): 388–93. http://dx.doi.org/10.1177/089719009801100509.

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Antidepressants have been successfully used for chronic pain syndromes for approximately 30 years. One theory is that analgesic action is secondary to the antidepressant effects of the medications. Placebo-controlled trials have documented that antidepressants treat neuropathic pain, musculoskeletal pain, chronic pain, and cancer pain. The most frequently studied antidepressant for pain is amitriptyline. Other antidepressants that have shown analgesic activity include imipramine, citalopram, paroxetine, nortriptyline, desipramine, and mianserin. Fluoxetine and trazodone have not been shown to
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Richelson, Elliott. "Pharmacology of antidepressants." Mayo Clinic Proceedings 76, no. 5 (2001): 511–27. http://dx.doi.org/10.4065/76.5.511.

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Frazer, Alan. "Pharmacology of Antidepressants." Journal of Clinical Psychopharmacology 17 (April 1997): 2S—18S. http://dx.doi.org/10.1097/00004714-199704001-00002.

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Richelson, Elliott. "Pharmacology of Antidepressants." Psychopathology 20, no. 1 (1987): 1–12. http://dx.doi.org/10.1159/000284517.

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Cohen, Lawrence J., and C. Lindsay DeVane. "Clinical Implications of Antidepressant Pharmacokinetics and Pharmacogenetics." Annals of Pharmacotherapy 30, no. 12 (1996): 1471–80. http://dx.doi.org/10.1177/106002809603001216.

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OBJECTIVE: To review available data on pharmacokinetic and pharmacogenetic influences on the response to antidepressant therapy, analyze the mechanisms for and clinical significance of pharmacokinetic and pharmacogenetic differences, and explain the implications of pharmacokinetics and pharmacogenetics for patient care. DATA SOURCES: A MEDLINE search of English-language clinical studies, abstracts, and review articles on antidepressant pharmacokinetics, pharmacogenetics, and drug interactions was used to identify pertinent literature. DATA SYNTHESIS: The pharmacokinetic profiles of selected an
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Saraghi, Mana, Leonard Golden, and Elliot V. Hersh. "Anesthetic Considerations for Patients on Antidepressant Therapy – Part II." Anesthesia Progress 65, no. 1 (2018): 60–65. http://dx.doi.org/10.2344/anpr-65-01-10.

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Millions of patients take antidepressant medications in the United States for the treatment of depression or anxiety disorders. Some antidepressants are prescribed off-label to treat problems such as chronic pain, low energy, and menstrual symptoms. Antidepressants are a broad and expansive group of medications, but the more common drug classes include tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and monoamine oxidase inhibitors. A miscellaneous or “atypical” category covers other agents. Some herbal supplements that claim to
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Gers, Lynn, Mirko Petrovic, Stany Perkisas, and Maurits Vandewoude. "Antidepressant use in older inpatients: current situation and application of the revised STOPP criteria." Therapeutic Advances in Drug Safety 9, no. 8 (2018): 373–84. http://dx.doi.org/10.1177/2042098618778974.

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Objectives: Antidepressant use increases as age rises. Moreover, older patients are more sensitive to side effects and drug interactions. This descriptive study aims to map antidepressant use among patients at the geriatrics department of a university hospital and to evaluate whether prescribing happens in an evidence-based manner. Methods: Patients aged 75 years and over, admitted to the geriatrics department of the Middelheim Hospital in Antwerp between February and July 2017 were included. We checked whether they took antidepressants, which types and doses were prescribed, who prescribed th
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Saraghi, Mana, Leonard R. Golden, and Elliot V. Hersh. "Anesthetic Considerations for Patients on Antidepressant Therapy—Part I." Anesthesia Progress 64, no. 4 (2017): 253–61. http://dx.doi.org/10.2344/anpr-64-04-14.

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Millions of patients take antidepressant medications in the United States for the treatment of depression or anxiety disorders. Some antidepressants are prescribed off-label to treat problems such as chronic pain, low energy, and menstrual symptoms. Antidepressants are a broad and expansive group of medications, but the more common drug classes include tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and monoamine oxidase inhibitors. A miscellaneous or “atypical” category covers other agents. Some herbal supplements that claim to
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Cyr, Monica, and Candace S. Brown. "Nefazodone: Its Place among Antidepressants." Annals of Pharmacotherapy 30, no. 9 (1996): 1006–12. http://dx.doi.org/10.1177/106002809603000916.

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OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, adverse effects, and drug interactions of nefazodone, as well as to determine its place among currently available antidepressants. DATA SOURCES: A search of European and American literature using EMBASE and MEDLINE was completed. Nefazodone was the search term. DATA SYNTHESIS: Nefazodone is an antidepressant that blocks serotonin type 2 (5-HT2) receptors in addition to inhibiting the reuptake of serotonin and norepinephrine. In double-blind, placebo-controlled studies, nefazodone demonstrates antidepressant activity at dosages
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Dissertations / Theses on the topic "Pharmacology of antidepressants"

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Ordway, Gregory A. "Molecular Pharmacology of Antidepressants." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/8657.

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Wang, Haiyan. "Manipulation of ion channel function and its effects on the neuropharmacology of 5-hydroxytryptamine." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279930.

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Maurya, Manisha. "The effect of antidepressants on rodent brain glucocorticoid systems." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368872.

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Janger, Darren S. "The Collective Overuse of Antidepressants as a Psychological Defense Inhibiting Soul Opportunities." Thesis, Pacifica Graduate Institute, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10750296.

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<p> It is not the existence of depressive symptomology, but understanding the function and effect that should be central in how to best support patients. Even in cases of milder depression, phase-of-life issues, or adjustment-related depressive episodes, the myth of a magical pill, here an antidepressant, appeals to the human desire for cessation of whatever unpleasantness may be arising. As a collective, clinicians may be placating clients&rsquo; psychological defenses and natural desire to suppress or dissociate at the expense of allowing a soulful opportunity to work through and resolve cha
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Nomikos, George Goulielmos. "In vivo neurochemical effects of antidepressant treatments studied by microdialysis." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/31076.

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The present experiments investigated the effects of different antidepressant treatments on dopamine (DA) transmission by employing in vivo microdialysis in the nucleus accumbens (NAC) and the striatum of freely moving rats. The treatments were: a) the tricyclic antidepressant desipramine (DMI), b) the novel antidepressant drug bupropion, and c) electrically induced seizures (ECS). The following results were obtained: 1) Neither acute (5 mg/kg), nor chronic (5 mg/kg, b.i.d. X 21) DMI influenced basal interstitial concentrations of DA in the NAC or the striatum. Chronic DMI did not influence ap
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Slamon, Noreen Deborah Louise. "Studies on the toxicological and protective responses of cultured astrocytes to antidepressants." Thesis, University of Salford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313910.

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Berggård, Cecilia. "Transcription Factor AP-2 in Relation to Personality and Antidepressant Drugs." Doctoral thesis, Uppsala University, Department of Neuroscience, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4638.

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<p>The CNS monoaminergic systems are considered as the head engine regulating neuropsychiatric functions and personality. Transcription factor AP-2 is known to be essential for the development of the brainstem including the monoaminergic nuclei, and has the ability to regulate many genes in the monoaminergic systems. The ability of transcription factors to regulate specific gene expression, has lately made them hot candidates as drug targets. In this thesis, results indicating a role of AP-2 in the molecular effects of the antidepressant drugs citalopram and phenelzine, are presented. </p><p>A
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Damberg, Mattias. "Transcription Factor AP-2 in Relation to Serotonergic Functions in the Central Nervous System." Doctoral thesis, Uppsala University, Pharmacology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2532.

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<p>Eukaryotic gene transcription plays a regulatory role in mammalian developmental processes. It has been shown that transcriptional control is an important mechanism for specification of neurotransmitter phenotypes. In the mammalian central nervous system, the transcription factor AP-2 family is one of the critical regulatory factors for neural gene expression and neuronal development. It has been shown that several genes in the monoaminergic systems have AP-2 binding sites in regulatory regions, suggesting a regulatory role of AP-2 also in the adult brain. Brainstem monoamines are implicate
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Gurgel, Josà Alves. "AvaliaÃÃo dos efeitos antiinflamatÃrios dos antidepressivos clomipramina, amitriptilina e maprotilina." Universidade Federal do CearÃ, 2002. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=1187.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>No presente estudo avaliou-se os efeitos dos antidepressivos, amitriptilina (amt), clomipramina (clm) e maprotilina (mpt) em reaÃÃes inflamatÃrias. Ratos machos Wistar, 150-200g, foram divididos em cinco grupos (n=6), em experimentos de edema de pata (EP) e migraÃÃo de neutrÃfilos (MN) em bolsas de ar subcutÃnea. Amt, mpt (v.o.) e clm (i.p),10, 30 e 90mg/kg, foram administradas previamente ao estÃmulo inflamatÃrio (EI), carragenina (Cg-500 Â g/pata), fMLP (10â6M) ou dextran (Dx-300 Âg/pata). O edema foi aferido por hidropletismomet
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Peters, Eric James. "Pharmacogenetics of antidepressant response." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3251935.

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Books on the topic "Pharmacology of antidepressants"

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Stahl, S. M. Antidepressants. Cambridge University Press, 2009.

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Stahl, S. M. Antidepressants. Cambridge University Press, 2009.

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Antidepressants: Pharmacology, health effects and controversy. Nova Science Publishers, Inc., 2012.

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Leonard, B. E. Differential effects of antidepressants. Martin Dunitz, 1999.

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Psych, Healy David MRC, ed. Differential effects of antidepressants. Martin Dunitz, 1999.

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Giorgio, Racagni, and Brunello Nicoletta, eds. Critical issues in the treatment of affective disorders. Karger, 1994.

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Bennett, Shoshana S. Pregnant on Prozac: The essential guide to making the best decision for you and your baby. GPP Life, 2009.

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Quality, United States Agency for Healthcare Research and. Second-generation antidepressants in the pharmacologic treatment of adult depression: An update of the 2007 comparative effectiveness review : executive Summary. Agency for Healthcare Research and Quality, 2011.

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Stahl, S. M. Stahl's essential psychopharmacology: The prescriber's guide. 3rd ed. Edited by Stahl, S. M. the prescriber's guide. and Stahl, S. M. the prescriber's guide. Cambridge University Press, 2009.

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Stahl, S. M. the prescriber's guide. and Stahl, S. M. the prescriber's guide., eds. Stahl's essential psychopharmacology: The prescriber's guide. 3rd ed. Cambridge University Press, 2009.

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Book chapters on the topic "Pharmacology of antidepressants"

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Andrews, John S., and Roger M. Pinder. "Chemistry and pharmacology of novel antidepressants." In Antidepressants. Birkhäuser Basel, 2001. http://dx.doi.org/10.1007/978-3-0348-8344-3_9.

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Haefely, Willy. "Preclinical Pharmacology of Antidepressants." In Biological Psychiatry, Higher Nervous Activity. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-8329-1_15.

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Efinger, Vanessa, Walter E. Müller, and Kristina Friedland. "Antidepressants: Pharmacology and Biochemistry." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_26-1.

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Bhandari, Prasan. "Antidepressants." In Pharmacology Mind Maps for Medical Students and Allied Health Professionals. CRC Press, 2019. http://dx.doi.org/10.1201/9780429023859-23.

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Sjöqvist, F. "Pharmacogenetics of Antidepressants." In Clinical Pharmacology in Psychiatry. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74430-3_19.

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Ghose, Karabi. "Clinical pharmacology of lithium salts." In Antidepressants for Elderly People. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4899-3436-9_6.

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Ciraulo, Domenic A., Richard I. Shader, and David J. Greenblatt. "Clinical Pharmacology and Therapeuticsof Antidepressants." In Pharmacotherapy of Depression. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-435-7_2.

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Ciraulo, Domenic A., Lucy Tsirulnik-Barts, Richard I. Shader, and David J. Greenblatt. "Clinical Pharmacology and Therapeutics of Antidepressants." In Pharmacotherapy of Depression. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-792-5_2.

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Vestergaard, P., L. F. Gram, P. Kragh-Sørensen, P. Bech, N. Reisby, and T. G. Bolwig. "Therapeutic Potentials of Recently Introduced Antidepressants." In Clinical Pharmacology in Psychiatry. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78010-3_18.

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Rudorfer, M. V., M. Linnoila, and W. Z. Potter. "Accidental Antidepressants: Search for Specific Action." In Clinical Pharmacology in Psychiatry. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71288-3_18.

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Reports on the topic "Pharmacology of antidepressants"

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Viswanathan, Meera, Jennifer Cook Middleton, Alison Stuebe, et al. Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer236.

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Background. Untreated maternal mental health disorders can have devastating sequelae for the mother and child. For women who are currently or planning to become pregnant or are breastfeeding, a critical question is whether the benefits of treating psychiatric illness with pharmacologic interventions outweigh the harms for mother and child. Methods. We conducted a systematic review to assess the benefits and harms of pharmacologic interventions compared with placebo, no treatment, or other pharmacologic interventions for pregnant and postpartum women with mental health disorders. We searched fo
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