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1

Stahl, S. M. Antidepressants. Cambridge University Press, 2009.

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2

Stahl, S. M. Antidepressants. Cambridge University Press, 2009.

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3

Antidepressants: Pharmacology, health effects and controversy. Nova Science Publishers, Inc., 2012.

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4

Leonard, B. E. Differential effects of antidepressants. Martin Dunitz, 1999.

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5

Psych, Healy David MRC, ed. Differential effects of antidepressants. Martin Dunitz, 1999.

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6

Giorgio, Racagni, and Brunello Nicoletta, eds. Critical issues in the treatment of affective disorders. Karger, 1994.

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7

Bennett, Shoshana S. Pregnant on Prozac: The essential guide to making the best decision for you and your baby. GPP Life, 2009.

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8

Quality, United States Agency for Healthcare Research and. Second-generation antidepressants in the pharmacologic treatment of adult depression: An update of the 2007 comparative effectiveness review : executive Summary. Agency for Healthcare Research and Quality, 2011.

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9

Stahl, S. M. Stahl's essential psychopharmacology: The prescriber's guide. 3rd ed. Edited by Stahl, S. M. the prescriber's guide. and Stahl, S. M. the prescriber's guide. Cambridge University Press, 2009.

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10

Stahl, S. M. the prescriber's guide. and Stahl, S. M. the prescriber's guide., eds. Stahl's essential psychopharmacology: The prescriber's guide. 3rd ed. Cambridge University Press, 2009.

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11

M, Stahl S., ed. Stahl's essential psychopharmacology: The prescriber's guide. 3rd ed. Cambridge University Press, 2009.

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12

Essential psychopharmacology: The prescriber's guide. Cambridge University Press, 2006.

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13

Essential psychopharmacology: Neuroscientific basis and clinical applications. Cambridge University Press, 1998.

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14

Stahl, S. M. Essential psychopharmacology: Neuroscientific basis and clinical applications. Cambridge University Press, 1996.

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15

Thakore, L. Handbook of Pharmacology of Antidepressants. Science Press, 1998.

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16

Antidepressants. Birkhäuser Verlag, 2000.

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17

Monroe, Judy. Antidepressants (Drug Library). Tandem Library, 2001.

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18

Antidepressants (Drug Library). Enslow Publishers, 1997.

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19

J, Mendlewicz, Brunello Nicoletta, and Judd Lewis L, eds. New therapeutic indications of antidepressants. Karger, 1997.

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20

Ruth, Porter, Bock Gregory, Clark Sarah, Ciba Foundation, and Symposium on Depression, Antidepressants, and Receptor Sensitivity (1985 : Ciba Foundation), eds. Antidepressants and receptor function. Wiley, 1986.

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21

E, File S., ed. Psychopharmacology of anxiolytics and antidepressants. Pergamon, 1991.

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22

E, File Sandra, ed. Psychopharmacology of anxiolytics and antidepressants. Pergamon Press, 1991.

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23

Nobles, Ryan. Pharmacology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0008.

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This chapter focuses on principles of pharmacokinetics, pharmacodynamics, adverse effects, drug interactions, and common indications with regard to opioids, nonsteroidal anti-inflammatory agents, acetaminophen, anticonvulsants, and antidepressants. The questions are formulated to focus on the most relevant topics that may be tested on the listed medications, but it is not a comprehensive review. The information provided should be supplemented with additional study of the cited literature in the Further Reading section for each question.
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24

(Editor), Sheldon H. Preskorn, Christina Y. Stanga (Editor), John P. Feighner (Editor), and Ruth Ross (Editor), eds. Antidepressants: Past, Present and Future (Handbook of Experimental Pharmacology). Springer, 2004.

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25

Antidepressants (Milestones in Drug Therapy). Birkhauser, 2001.

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26

(Editor), Helmut Buschmann, Jörg Holenz (Editor), Antonio Párraga (Editor), Antoni Torrens (Editor), José Miguel Vela (Editor), and José Luis Díaz (Editor), eds. Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application. Wiley-VCH, 2007.

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27

Leonard, Brian E., and David Healy. Differential Effects of Antidepressants. Informa Healthcare, 1999.

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28

M, Briley, and Montgomery S. A, eds. Antidepressant therapy at the dawn of the third millennium. Mosby, 1998.

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29

Stahl, Stephen M. Essential Psychopharmacology: the Prescriber's Guide: Antidepressants (Essential Psychopharmacology Series). Cambridge University Press, 2006.

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30

Stahl's Essential Psychopharmacology - Prescriber's Guide. University of Cambridge ESOL Examinations, 2014.

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31

Harrison, Mark. Central nervous system. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198765875.003.0041.

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This chapter describes the pharmacology of the central nervous system as it applies to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of hypnotics and anxiolytics, antipsychotics, antimania drugs, tricyclic antidepressants, nausea and vomiting, analgesics, non-opioid analgesics, opioid analgesics, antiepileptics, and status epilepticus. This chapter is laid out exactly following the RCEM syllabus, to allow easy reference and consolidation of learning.
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32

1941-, Gastpar M., and Wakelin J. S, eds. Selective 5-HT reuptake inhibitors: Novel or commonplace agents? Karger, 1988.

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33

Gastpar, M. Selective 5-Ht Reuptake Inhibitors: Novel or Commonplace Agents? (Advances in Biological Psychiatry). S. Karger Publishers (USA), 1988.

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34

(Editor), Husseini K. Manji, Charles L. Bowden (Editor), and Robert H., M.D. Belmaker (Editor), eds. Bipolar Medications: Mechanisms of Action. American Psychiatric Publishing, Inc., 2000.

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35

Bipolar medications : mechanisms of action. American Psychiatric Press, 2000.

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36

(Editor), Erminio Costa, ed. Gaba Receptors and Anxiety: From Neurobiology to Treatment (Advances in Biochemical Psychopharmacology). Raven Pr, 1995.

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37

Jolly, Elaine, Andrew Fry, and Afzal Chaudhry, eds. Clinical pharmacology and therapeutics. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199230457.003.0005.

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Chapter 5 covers the basic science and clinical topics relating to clinical pharmacology and therapeutics which trainees are required to learn as part of their basic training and demonstrate in the MRCP. It covers pharmacodynamics, pharmacokinetics, drug metabolism and prescribing in special circumstances, drug interactions, adverse drug reactions, drug development, paracetamol poisoning, salicylate poisoning, lithium toxicity, digoxin toxicity, carbon monoxide poisoning, ethylene glycol poisoning, and tricyclic antidepressant poisoning.
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38

Tolin, David F., and Blaise L. Worden. Combining Pharmacotherapy and Psychological Treatments for OCD. Edited by Gail Steketee. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195376210.013.0081.

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This chapter reviews the outcome literature on the efficacy of combined pharmacotherapy and cognitive-behavioral therapy (CBT) for obsessive compulsive disorder (OCD). By far, most research on combinations of CBT and pharmacotherapy for OCD has examined antidepressant medications, particularly those in the serotonin reuptake inhibitor (SRI) class. Quantitative review of randomized studies in which treatments were combined simultaneously indicated that combined therapy shows a small but significant advantage over exposure and response prevention (ERP) monotherapy, and a moderate advantage over
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39

Tolin, David F., and Blaise L. Worden. Combining Pharmacotherapy and Psychological Treatments for OCD. Edited by Gail Steketee. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195376210.013.019_update_001.

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This chapter reviews the outcome literature on the efficacy of combined pharmacotherapy and cognitive-behavioral therapy (CBT) for obsessive compulsive disorder (OCD). By far, most research on combinations of CBT and pharmacotherapy for OCD has examined antidepressant medications, particularly those in the serotonin reuptake inhibitor (SRI) class. Quantitative review of randomized studies in which treatments were combined simultaneously indicated that combined therapy shows a small but significant advantage over exposure and response prevention (ERP) monotherapy, and a moderate advantage over
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40

1960-, Ozawa H., Saito Toshikazu, Takahata Naohiko 1932-, Nihon Seishin Shinkei Gakkai, and Symposium on Affective Disorders and Neuronal Signal Transduction (1996 : Sapporo-shi, Japan), eds. Signal transduction in affective disorders. Springer, 1998.

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41

Jani, Suni, Ryan Herringa, and Derek Hursey. Pharmacologic Treatment of Children with Trauma- and Stressor-Related Disorders. Edited by Frederick J. Stoddard, David M. Benedek, Mohammed R. Milad, and Robert J. Ursano. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457136.003.0023.

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This chapter reviews the principles of psychopharmacological treatment for trauma and stressor-related disorders in children. It will discuss emerging psychopharmacological treatments and theories of trauma- and stress-related disorders (TSRDs) common to childhood, reactive attachment disorder, and disinhibited social engagement disorder. Although there is limited literature on the role of pharmacotherapy in treating TSRDs in children, it has been recognized that α‎- and β‎-adrenergic blocking agents, novel antipsychotic agents, non-selective serotonin reuptake inhibitor antidepressants such a
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42

Nestler, Eric J. New Approaches for Treating Depression. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0030.

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Several obstacles have impeded the introduction of new antidepressant medications over the past six decades. These obstacles include our still rudimentary knowledge of the biological basis of depression, as well as difficulties in evaluating the therapeutic efficacy of new putative antidepressant mechanisms in pathophysiologically distinct subtypes of the syndrome. Despite these obstacles, several tangible steps can be taken to advance depression treatment moving forward. The field needs to continue to take advantage of serendipitous discoveries in humans, such as the demonstration of rapid an
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43

Venuto, Charles S., and Karl Kieburtz. Huntington Disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0008.

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The clinical management of Huntington’s disease entails pharmacologic interventions and nonpharmacologic supportive therapy. There are no treatments that can halt or alter the progression of disease, therefore the goal is to maximize function and optimize quality of life. Tetrabenazine is the only pharmacologic agent with regulatory approval for Huntington’s disease chorea; however, off-label use of antidopaminergic agents is common. Treatment of behavioral disturbances can be tailored to the specific symptoms by using antidepressant, antipsychotic, and anxiolytic agents. Clinical trials testi
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44

Hendrickson, Rebecca C., and Murray A. Raskind. Pharmacological Treatment of Nightmares, Sleep Disturbance, and Daytime Hyperarousal in PTSD: The Role of Prazosin, Other Noradrenergic Modulators, and Sedative Hypnotics or Commonly Used Sedating Medications. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0035.

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Disruption of stress-response systems contributes to the pathophysiology of post-traumatic stress disorder (PTSD). Consistent with this, daytime hyperarousal and nighttime sleep disruption, including trauma-related nightmares, are core symptoms of the disorder, often requiring targeted pharmacologic treatment. Although a variety of medications that target sleep–wake and arousal mechanisms are commonly used for this purpose, there remains the best empirical support for prazosin, a brain-active antagonist of the α‎1 noradrenaline receptor, with emerging evidence for doxazosin, a longer-acting me
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45

Elger, Bernice S. Management of sleep complaints in correctional settings. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199360574.003.0016.

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Inmates of correctional settings often seek health care for sleep and drug problems. Studies on insomnia in correctional institutions are scarce. Sleep problems among detainees are frequent. Appropriate evaluation and treatment remains a challenge in correctional settings. Correctional health professionals need appropriate education regarding insomnia evaluation and management. Guidelines should be based on the principle of equivalence of care and take into account all evidence from research in the community and in correctional settings. Priority should be given to assessing modifiable causes
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46

Krystal, John H., and Dennis S. Charney. Current Treatments for Depression. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0031.

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Depression is among the most common and disabling medical disorders worldwide. Pharmacotherapy plays an important role in its treatment, although only half of all depressed patients show full remission with currently available therapies. This chapter reviews the most common pharmacotherapies with respect to their mechanisms of action, efficacy, tolerability, and safety. It also considers pharmacologic approaches to treatment-resistant symptoms of depression including adjunctive pharmacotherapies and the emerging rapid-acting antidepressants. An important focus of current research is to devise
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47

Kramer, Peter D. Listening to Prozac: A Psychiatrist Explores Antidepressant Drugs and the Remaking of the Self. Penguin (Non-Classics), 1994.

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48

Kramer, Peter D. Listening to Prozac: A Psychiatrist Explores Antidepressant Drugs and the Remaking of the Self. Penguin (Non-Classics), 1994.

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49

Listening to Prozac : A Psychiatrist Explores Antidepressant Drugs and the Remaking of the Self. DIANE Publishing Company, 1998.

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50

Absalom, Anthony, and John Sear. Intravenous anaesthetics. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0015.

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In recent decades, increasing attention has been focused on the intravenous anaesthetic agents. This interest has been stimulated by the discovery and availability of agents with increasingly favourable pharmacokinetic and dynamic properties, coupled with advances in knowledge of pharmacology and advances in computer technology. For most patients and operative procedures, anaesthesia is induced with a bolus or fast infusion of a short-acting drug, most commonly propofol. Increasingly, anaesthesia is thereafter also maintained with an infusion of an agent with favourable kinetics, again usually
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