Relevant bibliographies by topics / Phenanthridinones

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Phenanthridinones'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Phenanthridinones"

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Aleti, Rajeshwar Reddy, Alexey A. Festa, Leonid G. Voskressensky, and Erik V. Van der Eycken. "Synthetic Strategies in the Preparation of Phenanthridinones." Molecules 26, no. 18 (2021): 5560. http://dx.doi.org/10.3390/molecules26185560.

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Phenanthridinones are important heterocyclic frameworks present in a variety of complex natural products, pharmaceuticals and displaying wide range of pharmacological actions. Its structural importance has evoked a great deal of interest in the domains of organic synthesis and medicinal chemistry to develop new synthetic methodologies, as well as novel compounds of pharmaceutical interest. This review focuses on the synthesis of phenanthridinone scaffolds by employing aryl-aryl, N-aryl, and biaryl coupling reactions, decarboxylative amidations, and photocatalyzed reactions.
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Ding, Xiaojuan, Lei Zhang, Yiyang Mao, et al. "Synthesis of Phenanthridinones by Palladium-Catalyzed Cyclization of N-Aryl-2-aminopyridines with 2-Iodobenzoic Acids in Water." Synlett 31, no. 03 (2019): 280–84. http://dx.doi.org/10.1055/s-0039-1691538.

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The first Pd-catalyzed cyclization of N-aryl-2-aminopyridines with 2-iodobenzoic acids for the synthesis of phenanthridinones through C–H bond activation under very low catalyst loadings (down to 0.1 mol% Pd) in water is reported. This protocol features a broad substrate scope and provides easy efficient access to various phenanthridinones.
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Zhao, Lingyu, Guodong Shen, Tongxin Zhang, Zhen Wang та Yuhua Liang. "Pd/C-Catalyzed Intramolecular C–H Arylation for the Synthesis of Phenanthridinones and Dibenzo-α-pyrones". SynOpen 01, № 01 (2017): 0129–37. http://dx.doi.org/10.1055/s-0036-1591503.

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Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly active catalytic system of Pd/C-KOAc-DMA in moderate to excellent yields. The high catalytic activity, high recyclability, low costs, and ease of removal of Pd/C, combined with its commercial availability, render this protocol attractive for both synthetic and industrial applications.
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Li, Dengke, Ning Xu, Yicheng Zhang, and Lei Wang. "A highly efficient Pd-catalyzed decarboxylative ortho-arylation of amides with aryl acylperoxides." Chem. Commun. 50, no. 94 (2014): 14862–65. http://dx.doi.org/10.1039/c4cc06457g.

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Sharma, Sushila, Manoranjan Kumar, Shruti Sharma, et al. "Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C–H arylation." Organic & Biomolecular Chemistry 14, no. 36 (2016): 8536–44. http://dx.doi.org/10.1039/c6ob01362g.

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Pimparkar, Sandeep, and Masilamani Jeganmohan. "Palladium-catalyzed cyclization of benzamides with arynes: application to the synthesis of phenaglydon and N-methylcrinasiadine." Chem. Commun. 50, no. 81 (2014): 12116–19. http://dx.doi.org/10.1039/c4cc05252h.

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Liang, Dongdong, Deanna Sersen, Chao Yang, et al. "One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides." Organic & Biomolecular Chemistry 15, no. 20 (2017): 4390–98. http://dx.doi.org/10.1039/c7ob00649g.

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Chen, Yan-Fu, Yi-Sheng Wu, Yu-Huei Jhan, and Jen-Chieh Hsieh. "An efficient synthesis of (NH)-phenanthridinones via ligand-free copper-catalyzed annulation." Org. Chem. Front. 1, no. 3 (2014): 253–57. http://dx.doi.org/10.1039/c3qo00082f.

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Hu, Quan-Fang, Tian-Tao Gao, Yao-Jie Shi, Qian Lei, and Luo-Ting Yu. "Palladium-catalyzed intramolecular C–H arylation of 2-halo-N-Boc-N-arylbenzamides for the synthesis of N–H phenanthridinones." RSC Advances 8, no. 25 (2018): 13879–90. http://dx.doi.org/10.1039/c8ra02099j.

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Fang, Y., and G. K. Tranmer. "Continuous flow photochemistry as an enabling synthetic technology: synthesis of substituted-6(5H)-phenanthridinones for use as poly(ADP-ribose) polymerase inhibitors." MedChemComm 7, no. 4 (2016): 720–24. http://dx.doi.org/10.1039/c5md00552c.

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Methods utilizing continuous flow photochemistry have been developed for the synthesis of phenanthridinones via an intramolecular photochemical cyclization reaction in yields up to 99%, as a means to generate poly(ADP-ribose) polymerase inhibitors.
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Dissertations / Theses on the topic "Phenanthridinones"

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Griffiths, Natalie Jane. "Design, synthesis and biological evaluation of narciclasine analogues." Thesis, University of Bath, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687347.

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Whilst the cultivation of the Amaryllidaceae genus has primarily been for their ornamental properties, their use in traditional medicine is also well documented. Although over 100 alkaloids from this genus have been isolated, the phenanthridinone analogues narciclasine and pancratistatin isolated from the daffodil bulb, are particularly interesting due to their cytostatic and cytotoxic properties. They have potent and selective anticancer activity which is seemingly unique when compared to currently available chemotherapeutic agents. However, they have yet to be fully exploited as therapeutic
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Jhan, Yu-Huei, and 詹于慧. "Copper-catalyzed intramolecular C-N coupling reaction for the synthesis of oxindoles and phenanthridinones." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/7sezns.

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碩士<br>淡江大學<br>化學學系碩士班<br>101<br>The 1st Part: Variously synthetic methods of 3,3 spiro-oxindole derivatives were carried out and comparison of the mechanisms for different pathway was discussed. The 2st Part: An efficient copper-catalyzed intramolecular N-arylation was carried out by involving 2,2-substituted 2-(2-bromoaryl)acetamide to afford various substituted oxindoles with a small amount of Cu2O and benzene-1,2-diamine as catalytic system under aerobic conditions, which provided good to excellent yields with tolerance of wide variety of substrates. The 3st Part: An efficient copper-cat
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Fang, Yuhua. "The application of flow chemistry techniques in medicinal chemistry programs: the development of flow-photocyclization methods for the synthesis of phenanthridinone-type compounds." 2016. http://hdl.handle.net/1993/31817.

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Flow chemistry can be characterized as a continuous chemical reaction system performed in solution in connecting tubing and flow reactors which is efficient. Photochemistry is the chemical reaction initiated by light, and is the result of the absorption of photon by a reagent or starting material. Poly (ADP-ribose) polymerase is a big family of proteins related to cellular repair and death. Phenanthridinones have been shown to exhibit PARP inhibitory potency as competitive inhibitors. Instead of using conventional costly and low-efficiency coupling reactions, we have managed to develop a metho
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Lu, WenDer, and 盧文德. "Synthesis of Phenanthridinones and Biaryls via Anionic Cycloaromatization of 1-Aryl-3-decen-1,5-diynes." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/42004159061960805616.

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碩士<br>高雄醫學大學<br>藥學研究所<br>89<br>In this thesis, we describes the anionic cycloaromatization of 1-aryl-3-decen-1,5-diynes initiated by methoxide addition. We found that reaction of 2-(3-undecen-1,5-diynyl)benzonitrile with sodium methoxide in the presence of polar aprotic solvent, such as DMSO, HMPA, THF or crown ether gave phenanthridinones in good chemical yields. On the other hand, under the same reaction conditions, methanolysis of 1-aryl-3-decen-1,5-diynes in the presence of tetra-butylammonium iodide in refluxing methanol gave biaryl products, yields ranging from 14﹪to 52﹪.The results sug
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Wu, Yi-Sheng, and 吳宜聲. "Copper-catalyzed domino reaction to synthesize phenanthridinone scaffold." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/88907423615915999258.

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碩士<br>淡江大學<br>化學學系碩士班<br>101<br>The 1st Part: An efficient Cu-catalyzed O-arylation was carried out by involving phenols with iodoarenes to afford various substituted diarylether derivatives with a small amount of Cu2O and 1H-imidazole-4-carboxylic acid as catalytic system under mild conditions, which provided good to excellent yields with good tolerance of functional groups. The 2st Part: Copper-catalyzed domino reaction of 2&apos;&apos;-bromo-2-cyanobiphenyl through C-N bond formation under ligand-free and milder conditions to synthsize phenanthridinone scaffold. The reaction tolerat
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Chen, Yan-Fu, and 陳彥甫. "Copper-catalysed cascade reaction involving addition of nitrile and annulation to form the phenanthridinone and phenanthridine derivatives." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/43406745722673283930.

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碩士<br>淡江大學<br>化學學系碩士班<br>102<br>The 1st Part: copper-catalyzed cascade reaction of C–O and C–N bond coupling. This method efficiently provides poly-substituted (NH)- phenanthridinones in moderate to good yields with tolerance of a wide variety of substrates. The 2st Part: copper-catalyzed annulation reaction involving addition of the Grignard reagent to nitrile and C–N bond coupling. This method efficiently provides poly-substituted phenanthridines in moderate to good yields with tolerance of a very wide variety of substrates.
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Lee, Tai-Hua, and 李岱樺. "Palladium-catalyzed oxidative insertion of carbon monoxide to N-sulfonyl-2-aminobiaryls and 2-phenylphenols through C−H bond activation: access to bioactive phenanthridinone and benzopyranone derivatives in one pot." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/88753078776312877784.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>101<br>In this thesis, we investigated palladium-catalyzed oxidative carbonylation of N-sulfonyl-2-aminobiaryls through C–H bond activation and C–C, C–N bond formation under milder conditions to synthesize bioactive phenanthridinone derivatives in one pot, and we also applied the method of palladium-catalyzed oxidative carbonylation to 2-aryphenols via one O–H and C–H bond cleavage and one new C–C and C–O bond formation under similar conditions. Both reactions tolerated a variety of substrates and provided biologically important phenanthridinone and benzopyranone d
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Book chapters on the topic "Phenanthridinones"

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Keller, P. A. "Phenanthridinones." In Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-015-01811.

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Keller, P. A. "Reduction of Phenanthridinones." In Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-015-01788.

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"Product Class 12: Phenanthridinones and Related Systems." In Category 2, Hetarenes and Related Ring Systems, edited by Black. Georg Thieme Verlag, 2005. http://dx.doi.org/10.1055/sos-sd-015-01810.

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Conference papers on the topic "Phenanthridinones"

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SanMartin, Raul, Nerea Conde, Fátima Churruca, María Herrero, and Esther Domínguez. "A more efficient entry to phenanthridinone." In MOL2NET 2016, International Conference on Multidisciplinary Sciences, 2nd edition. MDPI, 2016. http://dx.doi.org/10.3390/mol2net-02-h002.

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Journal articles
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