Academic literature on the topic 'Phenothiazine'

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Journal articles on the topic "Phenothiazine"

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K ymet Berkil Akar, K. ymet Berkil Akar, and O. uzhan Bebek and Bar Eran O uzhan Bebek and Bar Eran. "Synthesis and Characterization of 1,4-Dibromo-5H-benzo[a]phenothiazin-5-one and 8,13-Dibromo-7H-naphtho[2,3-a]phenothiazin-7-one for Use as Novel Fingermark Visualisation Reagents." Journal of the chemical society of pakistan 46, no. 3 (2024): 322. http://dx.doi.org/10.52568/001464/jcsp/46.03.2024.

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In the presented study, novel compounds bearing the benzo[a]phenothiazine or naphtho[a]phenothiazin skeletons were developed for the first time as fingermark detecting reagents on paper surfaces which were then investigated in detail. First, two phenothiazine derivatives, 1,4-dibromo-5H-benzo[a]phenothiazin-5-one and 8,13-dibromo-7H-naphtho[2,3-a]phenothiazin-7-one were synthesized and characterized by spectroscopic methods. The phenothiazines were tested as potential reagents for latent fingermarks on copier paper and were then compared with 1,8-diazofluoren-9-one (DFO). Both compounds reacte
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Khadieva, Alena I., Vladimir V. Gorbachuk, and Ivan I. Stoikov. "Oligomerization of phenothiazin-5-ium tetraiodide in the presence of bases." Butlerov Communications 62, no. 6 (2020): 34–39. http://dx.doi.org/10.37952/roi-jbc-01/20-62-6-34.

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Methylene blue and its structural analogs (phenothiazine derivatives) are well known photodynamically and photochemically active agents, which are used in modern medicine, biology, and industry due to their low toxicity, high absorption in the therapeutic window region (600-660 nm). Methylene blue being one of the most studied phenothiazine derivative is employed as an antibacterial agent and also as an antidote to cyanide, carbon monoxide and hydrogen sulfide. Phenothiazin-5-ium tetraiodide is one of the most convenient precursors for the synthesis of structural analogues of methylene blue am
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Durst, R., P. Rosca-Rebaudengo, and D. Admon. "Phenothiazine-Associated Supraventricular Tachycardia." Australian & New Zealand Journal of Psychiatry 28, no. 2 (1994): 333–36. http://dx.doi.org/10.1080/00048679409075649.

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Psychotropic medications, mainly phenothiazines, are known to be associated with cardiac insult. The case report presented here describes nearly fatal arrhythmia (sustained supraventricular tachycardia) consequent to phenothiazine treatment. The authors aim to alert psychiatrists to the possible adverse, and even fatal, effects of phenothiazines.
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Alexandrovsky, V. N., S. S. Petrikov, and M. V. Kareva. "Acute poisoning with phenothiazine neuroleptics. Phenothiazine coma." Toxicological Review, no. 3 (July 18, 2021): 16–27. http://dx.doi.org/10.36946/0869-7922-2021-29-3-16-27.

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The article summarizes the authors' long-term experience in the diagnosis and treatment of acute poisoning with phenothiazine derivatives and presents data on the epidemiology of the effects of phenothiazines on the central nervous system. The original classification of acute phenothiazine intoxication confirmed by electrophysiological studies of the brain is given. The involvement of deep brain structures in the pathogenesis of acute phenothiazine coma has been confirmed. Based on studies of visual evoked potentials, the absence of inhibition of deep brain structures despite a pronounced coma
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(Miss), A. M. DAVE, N. BHATT K., K. UNDAVIA N., and B. TRIVEDl P. "Studies on Synthesis of Haloginated Phenothiazine Derivatives." Journal of Chemical Indian Society Vol. 65, May 1988 (1988): 365–66. https://doi.org/10.5281/zenodo.6279483.

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University Department of Chemistry, Bhavnagar University Bhavnagar-.364-002 <em>Manuscript received 12 October 1987, revised 4 February 1988, accepted 21 March 1988</em> 1,3,7,9-Tetrachloro-10-(substituted-benzthiazol-2<em>&#39;</em>-ylaminoacetyl)phenothiazines have been synthesised by condensation of the chloroacetyl derivative of phenothiazine with substituted-2-aminobenzthiazoles. The haloginated derivatives of phenothiazine were screened for their antibacterial efficacy.
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Schmidt, Maximilian, Mathias Hermann, Fabian Otteny, and Birgit Esser. "Calix[n]phenothiazines: Optoelectronic and Structural Properties and Host–Guest Chemistry." Organic Materials 02, no. 03 (2020): 235–39. http://dx.doi.org/10.1055/s-0040-1714295.

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Calixarenes are of interest as receptors for ions and small molecules and as organic materials. Exchanging the arene units through heteroaromatics allows changing their optoelectronic and host–guest properties. We herein present calix[n]phenothiazines (n = 3, 4) as novel macrocycles, accessible in two-step syntheses. The phenothiazine units show reversible redox events and emissive properties, and N-hexyl-substituted calix[3]phenothiazine binds to both ammonium ions and a bisimidazole as neutral guests.
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Kapoor, D., and P. Gupta. "Synthesis and Characterization of Phenothiazine Derivatives." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 57–70. https://doi.org/10.5281/zenodo.13742728.

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A series of new phenothiazine derivatives have been synthesized in which diphenylamine on treatment with sulphur give 10<em>H</em>-phenothiazinewhich on reaction with ethylchloro acetate yielded 2-(10<em>H</em>-phenothiazin-10-yl)acetate which on further treatment with hydrazine hydrate produced 2-(10<em>H</em>-phenothiazin-10-yl) acetohydrazide<strong>. </strong>Condensation of chief intermediate with various benzaldehyde derivatives afforded<em> N'</em>-(substitutedbenzylidene)-2-(10<em>H-</em>phenothiazin-10-yl) acetohydrazide. All the synthesized derivatives have been characterized by FTIR
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Young, Allan, and Robert Kehoe. "Two Cases of Agranulocytosis on Addition of a Butyrophenone to a Long-Standing Course of Phenothiazine Treatment." British Journal of Psychiatry 154, no. 5 (1989): 710–12. http://dx.doi.org/10.1192/bjp.154.5.710.

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Two cases of agranulocytosis occurring after addition of a butyrophenone to a course of phenothiazine treatment are reported and possible mechanisms for this interaction are discussed. Agranulocytosis is a well-documented adverse effect of phenothiazine administration (Vincent, 1986). Important factors are the total amount of drug given and the duration of administration. Agranulocytosis usually occurs within the first three months of therapy (Pisciotta, 1971; Marcus &amp; Mulvihill, 1978) and the relationship with the cumulative dose has been emphasised (Ananth et al, 1973). Agranulocytosis f
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Tarapdar, Abed, James K. S. Norris, Oliver Sampson, Galina Mukamolova, and James T. Hodgkinson. "The design and synthesis of an antibacterial phenothiazine–siderophore conjugate." Beilstein Journal of Organic Chemistry 14 (October 16, 2018): 2646–50. http://dx.doi.org/10.3762/bjoc.14.242.

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Siderophore–antibiotic conjugates consist of an antibiotic covalently linked by a tether to a siderophore. Such conjugates can demonstrate enhanced uptake and internalisation to the bacterial cell resulting in significantly reduced MIC values and extended spectrum of activity. Phenothiazines are a class of small molecules that have been identified as a potential treatment for multidrug resistant tuberculosis and latent TB. Herein we report the design and synthesis of the first phenothiazine–siderophore conjugate. A convergent synthetic route was developed whereby the functionalised phenothiazi
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Zhuravkov, Sergey P., Elena L. Boytsova, and Anastasia V. Slavinskaya. "STABILIZATION OF POLYETHYLENE AND OTHER POLYOLEFINS BY PHENOTHIAZINE DERIVATIVES." ChemChemTech 67, no. 12 (2024): 96–101. https://doi.org/10.6060/ivkkt.20246712.6941.

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This paper presents the results of the synthesis and study of the thermostabilizing properties of a number of new derivatives, as well as previously known derivatives of Phenothiazine (PT). The objects of the study were: cis-10-propenylphenothiazine (cis-10-PPT), 1-ethyl-2-methyl-3-(10H-phenothiazin-10-yl)-2,3-dihydro-1H-pyrido[3,2,1-kl]phenothiazine. Propenylphenothiazine dimer (DPРT),1-ethyl-2-methyl-3-(5-oxido-10H-phenothiazin-10-yl)-2,3-dihydro-1H-pyrido[3,2,1-kl]phenothiazine 7-oxide. S-oxide (DPРTО),1-ethyl-2-methyl-1H-pyrido-[3,2,1-k,l]phenothiazine. Pyridophenothiazine (PyrPT) and a mi
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Dissertations / Theses on the topic "Phenothiazine"

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Xiao, Shaorong. "The electrochemistry of phenothiazine derivatives." Thesis, University of Central Lancashire, 2000. http://clok.uclan.ac.uk/20876/.

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Methylene blue derivatives (MBDs) such as methylene blue (MB -), 1-methyl methylene blue (1MMB) and 1,9-dimethyl-methylene blue (DMMB) have potential use as drugs within photodynamic therapy (PDT). Knowing the redox properties of MBDs will help in understanding the way in which MBDs interact with a range of biological systems. In this work, the electrochemical behaviour of MBDs at various solution pHs have been studied for the first time on gold microdisc electrodes using steady state and non-steady state cyclic voltammetric methods. Steady-state studies The reduction of MBDs is an ECE(CC) pro
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Jones, T. "Structure disposition relationships amongst phenothiazine drugs." Thesis, Cardiff University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379191.

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Antunes, Edith Martins. "Stability of prochlorperazine in solution and in the solid-state." Thesis, Rhodes University, 2000. http://hdl.handle.net/10962/d1016399.

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Prochlorperazine, a member of the piperazine subclass of phenothiazines, widely used as an anti-emetic, is susceptible to oxidation to sulfoxides. These are main metabolites and degradants of all phenothiazines which are found to be inactive at the dopamine receptors. Prochlorperazine causes photosensitivity effects in patients attributed to dechlorination at C2 with the release of HCI (Huang and Sands, 1967; Nejmeh and Pilpel, 1978; Moore and Tamat, 1980). The aim of this study is to investigate the thermal and photostability of prochlorperazine edisylate and mesylate salts in the solid state
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Drummond, Patricia Mary. "A comparative photostability study of four propyl piperzine-substituted phenothiazines." Thesis, Rhodes University, 1997. http://hdl.handle.net/10962/d1003234.

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Four structurally related phenothiazines available in South Africa in a variety of dosage forms and as fine chemicals were investigated to ascertain whether their structural differences in terms of the 2-chloro-/ trifluoromethyl-substituents on the phenothiazine nucleus and the methyl-/ ß-hydroxethyl groups on the piperazine ring accouning for the differences in pharmacological activity can be correlated with their photostability².The four propyl piperazine-substituted derivatives are ranked in the following decreasing order of neuroleptic activity: fluphenazine> trifluoperazine> perphenazine
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Fenart, Naud Dominique. "La photosensibilite au neuriplege : a propos de 8 observations, photo-allergie croisee entre la chlorproethazine et les autres phenothiazines." Lille 2, 1988. http://www.theses.fr/1988LIL2M103.

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Silenzi, Ilaria. "Synthesis, characterization and conformational studies of bis-phenothiazine-aryl-boranes." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/19201/.

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This thesis project presents a work based on the study of a particular class of amino-boranes, called bis-phenothiazine-aryl-boranes. The peculiarity of these compounds is the N-B-N chemical moiety and their complex conformational behaviour, due to the combination of steric hindrance and conjugation of the B-N bond. Our work is focused on two main products with different symmetry: bis-phenothiazine-2-methylnaphthyl-borane (2b) and bis-phenothiazine-anthracenyl-borane (2c). We firstly focused our attention on an effective way of synthesis, by optimizing both reaction conditions and purification
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Shirdel, Javid. "Photo-physical characterization of flavin-pyrene-phenothiazine molecular photonic complexes." [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=985128062.

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Wilson, Beth. "Syntheses and DNA Interactions of Acridine and Phenothiazine Based Photosensitizers." Digital Archive @ GSU, 2006. http://digitalarchive.gsu.edu/chemistry_diss/8.

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Photosensitizing molecules and/or metal complexes that interact with DNA via intercalation and groove binding have potential applications as molecular structural probes, as footprinting reagents and in photodynamic therapeutics. To this regard, small molecules that bind to DNA and the energetics involved in these interactions, acridine-based therapeutics, photosensitization, photodynamic therapy, phenothiazine-mediated photosensitization, DNA photocleavage reaction mechanisms and photosensitizing metal complexes are introduced in Chapter I. Next, in Chapter II, the synthesis of a photonuclease
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Takorabet, Lila. "Immuno-régulation de la fonction thyroïdienne par une phenothiazine, l'alimemazine." Paris 5, 1996. http://www.theses.fr/1996PA05CD05.

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La glande thyroïde est le siège de deux maladies auto-immunes : la thyroïdite de Hashimoto et la maladie de Basedow. Ces deux pathologies qui sont opposées tant par leur caractéristiques immunologiques qu'endocrinologiques sont d'origine multifactorielles : c'est de l'interaction de plusieurs facteurs de risque que naît la maladie. Cependant, la capacité d'expression par les cellules épithéliales thyroïdiennes (CET) des molécules de classe II du complexe majeur d'histocompatibilité (CMH) au cours de pathologie auto-immune thyroïdienne, transforme ces cellules en cellule présentatrice d'antigèn
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Meary, Alexandre. "Schizophrenie et cancer du poumon." Paris 6, 2001. http://www.theses.fr/2001PA062055.

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Books on the topic "Phenothiazine"

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Ghuwar, Ramadan. Aspects of the analytical chemistry of phenothiazine drugs. University of Salford, 1995.

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International Conference on Phenothiazines and Structurally Related Psychotropic Compounds (6th 1990 Pasadena, Calif.). Thiazines and structurally related compounds: Proceedings of the Sixth International Conference on Phenothiazines and Structurally Related Psychotropic Compounds, Pasadena, California, September 11-14, 1990. Edited by Keyzer Hendrik and Eckert George M. Krieger Pub. Co., 1992.

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1941-, Gupta R. R., ed. Phenothiazines and 1,4-benzothiazines: Chemical and biomedical aspects. Elsevier, 1988.

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Allenby, Gordon Micheal. Binding of Phenothiazine Derivatives by Proteins and Nucleic Acid, and the Effect of Phenothiazine and Phenothiazine Derivatives on Some Respiratory Enzymes. Creative Media Partners, LLC, 2021.

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The 2006-2011 World Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007-2012 World Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives. ICON Group International, Inc., 2006.

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Amma, Manju Thankamoni. Mechanistic investigations on the reactivity of 10-methyl phenothiazine with singlet oxygen. 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in India. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in Japan. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in Greater China. ICON Group International, Inc., 2006.

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Book chapters on the topic "Phenothiazine"

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Rao, M. L., M. Bagli, J. Fritze, G. Laux, and P. König. "Phenothiazine." In Neuro-Psychopharmaka Ein Therapie-Handbuch. Springer Vienna, 1998. http://dx.doi.org/10.1007/978-3-7091-6458-7_5.

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Scahill, Lawrence David. "Phenothiazine." In Encyclopedia of Autism Spectrum Disorders. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_1254.

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Scahill, Lawrence David. "Phenothiazine." In Encyclopedia of Autism Spectrum Disorders. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-91280-6_1254.

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Peter, Helga. "Phenothiazine." In Springer Reference Medizin. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-642-54672-3_749-1.

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Peter, Helga. "Phenothiazine." In Springer Reference Medizin. Springer Berlin Heidelberg, 2025. https://doi.org/10.1007/978-3-662-65186-5_749.

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Alcolea Palafox, M., J. L. Núñez, M. Gil, and G. Tardajos. "Infrared Study of Phenothiazine and N-Methyl Phenothiazine." In Spectroscopy of Biological Molecules: New Directions. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4479-7_275.

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Saller, Reinhard. "Neuroleptika (Phenothiazine, Butyrophenone)." In Metoclopramid als Standardantiemetikum in der Behandlung zytostatikainduzierten Erbrechens. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77782-0_14.

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Palafox, M. Alcolea, G. Tardajos, J. L. Núñez, T. Sanz-García, and N. Iza. "Quantum Chemical Predictions of the NMR Spectrum of Phenothiazine and N-Methyl Phenothiazine." In Spectroscopy of Biological Molecules: New Directions. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4479-7_195.

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BRAUN, A. M., M. A. GILSON, M. KRIEG, M. T. MAURETTE, P. MURASECCO, and E. OLIVEROS. "Electron and Energy Transfer from Phenothiazine Triplets." In ACS Symposium Series. American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0278.ch006.

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Attwood, D., E. Boitard, J. P. Dubès, H. Tachoire, V. Mosquera, and V. Perez Villar. "Association Models for Phenothiazine Drugs in Aqueous Solution." In The Structure, Dynamics and Equilibrium Properties of Colloidal Systems. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-011-3746-1_8.

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Conference papers on the topic "Phenothiazine"

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Blaja, Svetlana, Lidia Lungu, Kaleria Kuchkova, Alexandru Ciocarlan, and Aculina Aricu. "Synthesis of new molecular hybrids with phenothiazine fragment from norambreinolide." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab10.

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The known phenothiazine derivatives exhibit a wide spectrum of biological activities, including such as antiparasitic, antioxidant, anticancer, antiproliferative, antineoplastic, antimicrobial, etc. [1]. For this reason, terpeno-phenothiazine molecular hybrids represent one of the priority strategies of organic synthesis in the design of new bioactive compounds. Here are reported the results of the synthesis of new homodrimane hybrids with a phenothiazine fragment. Starting from (+)-sclareolide 1 the Δ8,13-bicyclohomofarnesoic acid 2 and 11-homodrim-6(8)-dien-12-oic acid 3 were synthesized in
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Choi, Dong H., Woong G. Jun, and Kwang Y. Oh. "Photorefractive molecular composite bearing the phenothiazine derivatives." In International Symposium on Optical Science and Technology, edited by Klaus Meerholz. SPIE, 2002. http://dx.doi.org/10.1117/12.454852.

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Rodrigues da Silva, Abdênego, Fernanda Viana Cabral, Adriana Fontes, and Martha Ribeiro Simões. "Light-based antifungal strategy for the control of Candida auris." In Latin America Optics and Photonics Conference. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.w4a.58.

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Candida auris is a pathogen that has been attracting worldwide focus due to its high resistance to conventional drugs. This work evaluated the photodynamic inactivation mediated by two phenothiazine dyes against the CBS 10913 strain.
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Zhao, Tingting, Chuanbo Dai, and Yuting Gao. "RESEARCH PROGRESS OF PHENOTHIAZINE COMPOUNDS OF DIOXOPROMETHAZINE HYDROCHLORIDE." In International Conference on New Materials and Intelligent Manufacturing (ICNMIM). Volkson Press, 2018. http://dx.doi.org/10.26480/icnmim.01.2018.183.186.

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Posso, Marina Cassago, João Lourenço Serrano, Paulo Almeida, Fernanda Domingues, Samuel Silvestre, and Susana Ferreira. "New Fluoroquinolone–Phenothiazine Hybrids and Their Antimicrobial Activity." In The 2nd International Electronic Conference on Antibiotics—Drugs for Superbugs: Antibiotic Discovery, Modes of Action And Mechanisms of Resistance. MDPI, 2022. http://dx.doi.org/10.3390/eca2022-12722.

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Shirdel, J., A. Penzkofer, R. Procházka, Z. Shen, and J. Daub. "Photodynamics of pyrene-flavin and phenothiazine-flavin dyads." In The International Conference on Coherent and Nonlinear Optics, edited by Sergey A. Tikhomirov, Thomas Udem, Valery Yudin, Maxim Pshenichnikov, and Oleg M. Sarkisov. SPIE, 2007. http://dx.doi.org/10.1117/12.752443.

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Gomes Júnior, Rafael Araújo, Susana C. P. S. de Oliveira, Juliana S. C. Monteiro, et al. "Association phenothiazine and laser on growth ofC. tropicalisfluconazole-resistant." In SPIE BiOS, edited by Michael R. Hamblin, James D. Carroll, and Praveen Arany. SPIE, 2014. http://dx.doi.org/10.1117/12.2038566.

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Casson, Joanna L., Wenxi Huang, Yongwoo Lee, et al. "NLO studies of a novel phenothiazine self-assembled monolayer." In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, edited by Manfred Eich and Mark G. Kuzyk. SPIE, 1999. http://dx.doi.org/10.1117/12.368280.

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Bende, Attila. "Low-lying excited states and their relaxation pathways of phenothiazine." In 11TH INTERNATIONAL CONFERENCE OF PROCESSES IN ISOTOPES AND MOLECULES (PIM 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.5018273.

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Dzhons, Darja, and Andrei Budruev. "Photochemical modification of polymer surface with bifunctional dyes phenothiazine series." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-d004.

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