Academic literature on the topic 'Phenothiazine derivatives'

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Journal articles on the topic "Phenothiazine derivatives"

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Khadieva, Alena I., Vladimir V. Gorbachuk, and Ivan I. Stoikov. "Oligomerization of phenothiazin-5-ium tetraiodide in the presence of bases." Butlerov Communications 62, no. 6 (2020): 34–39. http://dx.doi.org/10.37952/roi-jbc-01/20-62-6-34.

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Methylene blue and its structural analogs (phenothiazine derivatives) are well known photodynamically and photochemically active agents, which are used in modern medicine, biology, and industry due to their low toxicity, high absorption in the therapeutic window region (600-660 nm). Methylene blue being one of the most studied phenothiazine derivative is employed as an antibacterial agent and also as an antidote to cyanide, carbon monoxide and hydrogen sulfide. Phenothiazin-5-ium tetraiodide is one of the most convenient precursors for the synthesis of structural analogues of methylene blue am
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(Miss), A. M. DAVE, N. BHATT K., K. UNDAVIA N., and B. TRIVEDl P. "Studies on Synthesis of Haloginated Phenothiazine Derivatives." Journal of Chemical Indian Society Vol. 65, May 1988 (1988): 365–66. https://doi.org/10.5281/zenodo.6279483.

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University Department of Chemistry, Bhavnagar University Bhavnagar-.364-002 <em>Manuscript received 12 October 1987, revised 4 February 1988, accepted 21 March 1988</em> 1,3,7,9-Tetrachloro-10-(substituted-benzthiazol-2<em>&#39;</em>-ylaminoacetyl)phenothiazines have been synthesised by condensation of the chloroacetyl derivative of phenothiazine with substituted-2-aminobenzthiazoles. The haloginated derivatives of phenothiazine were screened for their antibacterial efficacy.
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K ymet Berkil Akar, K. ymet Berkil Akar, and O. uzhan Bebek and Bar Eran O uzhan Bebek and Bar Eran. "Synthesis and Characterization of 1,4-Dibromo-5H-benzo[a]phenothiazin-5-one and 8,13-Dibromo-7H-naphtho[2,3-a]phenothiazin-7-one for Use as Novel Fingermark Visualisation Reagents." Journal of the chemical society of pakistan 46, no. 3 (2024): 322. http://dx.doi.org/10.52568/001464/jcsp/46.03.2024.

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In the presented study, novel compounds bearing the benzo[a]phenothiazine or naphtho[a]phenothiazin skeletons were developed for the first time as fingermark detecting reagents on paper surfaces which were then investigated in detail. First, two phenothiazine derivatives, 1,4-dibromo-5H-benzo[a]phenothiazin-5-one and 8,13-dibromo-7H-naphtho[2,3-a]phenothiazin-7-one were synthesized and characterized by spectroscopic methods. The phenothiazines were tested as potential reagents for latent fingermarks on copier paper and were then compared with 1,8-diazofluoren-9-one (DFO). Both compounds reacte
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Kapoor, D., and P. Gupta. "Synthesis and Characterization of Phenothiazine Derivatives." Pharmaceutical and Chemical Journal 3, no. 2 (2016): 57–70. https://doi.org/10.5281/zenodo.13742728.

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A series of new phenothiazine derivatives have been synthesized in which diphenylamine on treatment with sulphur give 10<em>H</em>-phenothiazinewhich on reaction with ethylchloro acetate yielded 2-(10<em>H</em>-phenothiazin-10-yl)acetate which on further treatment with hydrazine hydrate produced 2-(10<em>H</em>-phenothiazin-10-yl) acetohydrazide<strong>. </strong>Condensation of chief intermediate with various benzaldehyde derivatives afforded<em> N'</em>-(substitutedbenzylidene)-2-(10<em>H-</em>phenothiazin-10-yl) acetohydrazide. All the synthesized derivatives have been characterized by FTIR
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Saini, Pooja, Sushil Kumar, and Swatantr Bahadur Singh. "Molecular Docking, Synthesis and In vivo Assessment of New Phenothiazines as Inhibitors of Anxiety." Biosciences Biotechnology Research Asia 21, no. 4 (2024): 1485–93. https://doi.org/10.13005/bbra/3319.

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ABSTRACT: Background: Heterocylics are the backbone of the medicinal chemistry. They played very imperative role in the discovery of new lead molecules. Phenothiazine is one of them and it has many biological activities as well. This article proposed the design and synthesis of new phenothiazine derivatives. Aim: This work includes the preparation of some new Schiff bases of phenothiazine. The synthetic scheme includes development of series of 1-(10H-phenothiazin-10-yl)-2-(4-((phenylimino)methyl) phenoxy) ethan-1-one (D1-D10). Objective: This work aims to design some new phenothiazine molecule
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Środa-Pomianek, Kamila, Krystyna Michalak, Anna Palko-Łabuz, et al. "The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells." International Journal of Molecular Sciences 20, no. 4 (2019): 955. http://dx.doi.org/10.3390/ijms20040955.

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Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them. The effect of three phenothiazine derivatives that were used as single agents and in combination with simvastatin on cell growth, apoptosis induction, activity, and expression of cyclooxygenase-2 (COX-2) in doxorubicin-resistant colon cancer cells (LoVo/Dx) was investigated. Treatment of LoVo/Dx ce
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Zhuravkov, Sergey P., Elena L. Boytsova, and Anastasia V. Slavinskaya. "STABILIZATION OF POLYETHYLENE AND OTHER POLYOLEFINS BY PHENOTHIAZINE DERIVATIVES." ChemChemTech 67, no. 12 (2024): 96–101. https://doi.org/10.6060/ivkkt.20246712.6941.

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This paper presents the results of the synthesis and study of the thermostabilizing properties of a number of new derivatives, as well as previously known derivatives of Phenothiazine (PT). The objects of the study were: cis-10-propenylphenothiazine (cis-10-PPT), 1-ethyl-2-methyl-3-(10H-phenothiazin-10-yl)-2,3-dihydro-1H-pyrido[3,2,1-kl]phenothiazine. Propenylphenothiazine dimer (DPРT),1-ethyl-2-methyl-3-(5-oxido-10H-phenothiazin-10-yl)-2,3-dihydro-1H-pyrido[3,2,1-kl]phenothiazine 7-oxide. S-oxide (DPРTО),1-ethyl-2-methyl-1H-pyrido-[3,2,1-k,l]phenothiazine. Pyridophenothiazine (PyrPT) and a mi
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Saini, Pooja, and Sushil Kumar. "Synthesis, Characterization, Molecular docking and Anti-anxiety Evaluation of Some Novel Phenothiazine Derivatives." Oriental Journal Of Chemistry 39, no. 5 (2023): 1232–38. http://dx.doi.org/10.13005/ojc/390516.

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The phenothiazine derivatives 1-(10H-phenothiazin-10-yl)-2-(4-(1-(phenylimino)ethyl)phenoxy)ethan-1-one (4a-4j) are produced from 2-(4-acetylphenoxy)-1-(10H-phenothiazin-10-yl)ethan-1-one (3) and after that, condensing them with various carbonyl compounds. Acetonitrile was used as solvent. The purity of the analogues and reaction progress were identified through their retention factor value and melting point. Characterization of the prepared analogues was completed via performing their Infra-red, proton-nuclear magnetic resonance spectroscopy with their elemental analysis. The set of molecular
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Wu, San, Wei-Ye Hu, and Song-Lin Zhang. "Potassium carbonate-mediated tandem C–S and C–N coupling reaction for the synthesis of phenothiazines under transition-metal-free and ligand-free conditions." RSC Advances 6, no. 29 (2016): 24257–60. http://dx.doi.org/10.1039/c6ra01295g.

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A potassium carbonate-mediated tandem coupling reaction for the synthesis of phenothiazines is described. This protocol affords an efficient approach for the construction of phenothiazine derivatives without the need for addition of transition-metal catalyst or ligand.
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Swoboda, Daniel, Jacek E. Nycz, Nataliya Karaush-Karmazin, et al. "Synthesis and Spectroscopic Characterization of Selected Phenothiazines and Phenazines Rationalized Based on DFT Calculation." Molecules 27, no. 21 (2022): 7519. http://dx.doi.org/10.3390/molecules27217519.

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Two unique structures were isolated from the phosphorylation reaction of 10H-phenothiazine. The 5,5-dimethyl-2-(10H-phenothiazin-10-yl)-1,3,2-dioxaphosphinane 2-oxide (2a) illustrates the product of N-phosphorylation of phenothiazine. Moreover, a potential product of 2a instability, a thiophosphoric acid 2b, was successfully isolated and structurally characterized. Molecule 2a, similarly to sulfoxide derivative 3, possesses interesting phosphorescence properties due to the presence of d-pπ bonds. The X-ray, NMR, and DFT computational studies indicate that compound 2a exhibits an anomeric effec
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Dissertations / Theses on the topic "Phenothiazine derivatives"

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Xiao, Shaorong. "The electrochemistry of phenothiazine derivatives." Thesis, University of Central Lancashire, 2000. http://clok.uclan.ac.uk/20876/.

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Methylene blue derivatives (MBDs) such as methylene blue (MB -), 1-methyl methylene blue (1MMB) and 1,9-dimethyl-methylene blue (DMMB) have potential use as drugs within photodynamic therapy (PDT). Knowing the redox properties of MBDs will help in understanding the way in which MBDs interact with a range of biological systems. In this work, the electrochemical behaviour of MBDs at various solution pHs have been studied for the first time on gold microdisc electrodes using steady state and non-steady state cyclic voltammetric methods. Steady-state studies The reduction of MBDs is an ECE(CC) pro
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Schlauderer, Florian Michael [Verfasser], and Karl-Peter [Akademischer Betreuer] Hopfner. "Structural and functional analysis of MALT1 inhibition by phenothiazine derivatives / Florian Michael Schlauderer ; Betreuer: Karl-Peter Hopfner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1125371641/34.

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Fadiran, E. O. "Assay of phenothiazine sulphoxides by and temperature effects in second derivative spectrofluorimetry." Thesis, University of Strathclyde, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371950.

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Oliveira, Daniela Silva Barroso de. "aPDT: fotossensibilizadores e tempos de exposição de luz não inluenciaram na resposta tecidual de camundongos isogênicos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/58/58135/tde-22112016-101954/.

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O objetivo deste estudo foi avaliar a resposta do tecido conjuntivo subcutâneo de camundongos isogênicos após o uso da Terapia Fotodinâmica antimicrobiana (aPDT), utilizando dois fotossensibilizadores, Derivado fenotiazínico (Helbo Blue) e Curcumina, em diferentes tempos de aplicação de lasers (30 segundos, 1 minuto ou 2 minutos). Foram utilizados 141 camundongos isogênicos da linhagem BALB/c cujo tecido conjuntivo subcutâneo foi exposto aos dois fotossensibilizadores, e em seguida irradiado com laser diodo no grupo do Derivado Fenotiazínico e ao LED no grupo da Curcumina. Para cada fotossensi
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Yang, Chihjen, and 楊志仁. "Organic Phenothiazine Derivatives for Dye-Sensitized Solar Cells." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/40935044814850384122.

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碩士<br>國立中正大學<br>化學暨生物化學研究所<br>99<br>Dye-sensitized solar cells (DSSCs) based on organic dyes adsorbed on nanocrystalline TiO2 electrodes have received considerable attention because of their high incident solar light to-electricity conversion efficiency and low cost. A number of organic dyes have so far been developed and the relationship between their chemical structures and the photovoltaic performances of DSSCs based on the dyes has been studied. To create high-performance DSSCs, it is important to develop effective organic dye sensitizers, which should be optimized for the chemical structu
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Lin, Hsin-Hung, and 林信宏. "Synthesis, Spectral Investigations and Multiple Applications of Novel Phenothiazine derivatives." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/60634318208198261647.

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碩士<br>國立中興大學<br>化學系所<br>96<br>The major goal for our research is to use simple synthesized method for various fluorescence dye derivatives containing Phenothiazine core via Heck reaction and Suzuki coupling reaction that unprotected at 10N-H. Under various pH values and oxidation state, we research the spectrum property of fluorescence dye for Internal Charge Transfer and Photo-induced electron Transfer and applying for diagnosis cancer cell . The fluorescence-dye that our laboratory synthesis have two group : (Ⅰ) The PTZ-vinyl-derivatives have intense PL quantum yield and low energy UV absor
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Hsieh, Tung-Sheng, and 謝東昇. "Evaluation of Phenothiazine Derivatives – Selective Near-infrared Photodynamic Therapy and New Reactive Oxygen Species Photosensitizers." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/72335712794940966073.

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碩士<br>國立中興大學<br>生醫工程研究所<br>101<br>A series of 10H-phenothiazine (PTZ) derivative fluorophores ,Suzuki coupling with electron donating and/or withdrawing substitution group in 3, 7-position were prepared. In acidic condition, proton accepter groups aniline and dimethylaniline substituted PTZ derivatives could be protonated and aggregated to become fluorescent organic nanoparticles (FONs) accompany with fluorescent enhancement. On the other hand, anionic forms of these derivatives exhibited strong red light emission in alkali DMSO solutions, whereas anionic nitrobenzene and naphthaleneimide subs
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Books on the topic "Phenothiazine derivatives"

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Allenby, Gordon Micheal. Binding of Phenothiazine Derivatives by Proteins and Nucleic Acid, and the Effect of Phenothiazine and Phenothiazine Derivatives on Some Respiratory Enzymes. Creative Media Partners, LLC, 2021.

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The 2006-2011 World Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007-2012 World Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in India. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in Japan. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in Greater China. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007-2012 Outlook for Psychotherapeutic Tranquilizing Agents Excluding Phenothiazine Derivatives in the United States. ICON Group International, Inc., 2006.

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Book chapters on the topic "Phenothiazine derivatives"

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Cibotaru, Sandu, Valentin Nastasa, Andreea-Isabela Sandu, Andra-Cristina Bostanaru, Mihai Mares, and Luminita Marin. "PEG-Ylated Phenothiazine Derivatives. Synthesis and Antitumor Activity." In IFMBE Proceedings. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92328-0_65.

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Kitson, Trevor M., Kathryn E. Kitson, and Gordon J. King. "Covalent Modification of Sheep Liver Cytosolic Aldehyde Dehydrogenase by the Oxidative Addition of Coloured Phenoxazine, Phenothiazine and Phenazine Derivatives." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4735-8_11.

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Singh, Bhupinder, Christian Kaunert, Sahil Lal, Hind Hammouch, and Manmeet Kaur Arora. "Exploring the Biological Relevance of Fused S-Heterocycle Phenothiazine Derivatives." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch012.

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Phenothiazine and its derivatives have attracted a noteworthy attention within the medicinal chemistry' domain ascribed to its varied pharmacological activities and possible medically-beneficial applications. Fused S-heterocycle Phenothiazine being the most promising derivatives among all has displayed and showcased promising results in numerous biological evaluations. Phenothiazines are one of the class of compounds categorized by tricyclic structure which is comprised of central thiazine ring merged with two benzene rings. Such central thiazine rings incorporate the presence of sulphur atoms
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Yoshida, S., K. Kozawa, and T. Uchida. "Electrical properties of sublimed films of phenothiazine and phenoxazine derivatives." In Advanced Materials '93. Elsevier, 1994. http://dx.doi.org/10.1016/b978-1-4832-8380-7.50156-5.

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"Antidepressants Used as Chemotherapy for Trypanosoma cruzi Infection: Phenothiazines and Derivative Compounds." In Frontiers in Anti-Infective Drug Discovery, edited by Patricia Paglini Oliva, Silvina Lo Presti, and Walter Rivarola. BENTHAM SCIENCE PUBLISHERS, 2015. http://dx.doi.org/10.2174/9781681080826115040004.

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Conference papers on the topic "Phenothiazine derivatives"

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Blaja, Svetlana, Lidia Lungu, Kaleria Kuchkova, Alexandru Ciocarlan, and Aculina Aricu. "Synthesis of new molecular hybrids with phenothiazine fragment from norambreinolide." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab10.

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The known phenothiazine derivatives exhibit a wide spectrum of biological activities, including such as antiparasitic, antioxidant, anticancer, antiproliferative, antineoplastic, antimicrobial, etc. [1]. For this reason, terpeno-phenothiazine molecular hybrids represent one of the priority strategies of organic synthesis in the design of new bioactive compounds. Here are reported the results of the synthesis of new homodrimane hybrids with a phenothiazine fragment. Starting from (+)-sclareolide 1 the Δ8,13-bicyclohomofarnesoic acid 2 and 11-homodrim-6(8)-dien-12-oic acid 3 were synthesized in
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Choi, Dong H., Woong G. Jun, and Kwang Y. Oh. "Photorefractive molecular composite bearing the phenothiazine derivatives." In International Symposium on Optical Science and Technology, edited by Klaus Meerholz. SPIE, 2002. http://dx.doi.org/10.1117/12.454852.

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Kozawa, K., N. Uchida, H. Yoshida, N. Suzuki, Y. Hayashida, and T. Uchida. "Structure and electronic properties of iodine complexes with some phenothiazine derivatives." In International Conference on Science and Technology of Synthetic Metals. IEEE, 1994. http://dx.doi.org/10.1109/stsm.1994.835493.

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Park, Moo-Jin, and Hong-Ku Shim. "Synthesis, Characterization and Electroluminescence of Polyfluorene Copolymers with Phenothiazine Derivatives; Their Application to White- and Red-emitting PLEDs." In Solid-State and Organic Lighting. OSA, 2010. http://dx.doi.org/10.1364/soled.2010.jwa7.

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Bhoir, Siddhant, Javeena Hussain, Vibha Singh, et al. "Abstract 1264: Design, synthesis and biological evaluation of new phenothiazine derivatives as potential Tousled-like kinase 1 inhibitors in prostate cancer treatment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1264.

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Bhoir, Siddhant, Javeena Hussain, Vibha Singh, et al. "Abstract 1264: Design, synthesis and biological evaluation of new phenothiazine derivatives as potential Tousled-like kinase 1 inhibitors in prostate cancer treatment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1264.

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Cao, Huayu, Zhijian Chen, Yingliang Liu, et al. "A stable red emission in polymer light-emitting diodes based on phenothiazine derivative." In Photonics Asia 2007, edited by Jian Wang, Changhee Lee, and Hezhou Wang. SPIE, 2007. http://dx.doi.org/10.1117/12.757041.

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Oliveira, Susana C. P. S., Gustavo M. P. Santos, Juliana S. C. Monteiro, et al. "Photodynamic antimicrobial chemotherapy (PACT) using phenothiazines derivatives associated with the red laser againststaphylococcus aureus." In SPIE BiOS, edited by Michael R. Hamblin, James D. Carroll, and Praveen R. Arany. SPIE, 2013. http://dx.doi.org/10.1117/12.2005560.

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Monteiro, Juliana S. C., Susana C. P. S. Oliveira, Gustavo M. P. Santos, et al. "Photodynamic antimicrobial chemotherapy (PACT) using phenothiazines derivatives associated with the red-orange LED againststaphylococcus aureus." In SPIE BiOS, edited by Michael R. Hamblin, James D. Carroll, and Praveen R. Arany. SPIE, 2013. http://dx.doi.org/10.1117/12.2005591.

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de Oliveira, Susana C. P. S., Juliana S. C. Monteiro, Gustavo M. Pires-Santos, et al. "In vitro influence of photodynamic antimicrobial chemotherapy onstaphylococcus aureusby using phenothiazines derivatives associated with laser/LED light." In SPIE BiOS, edited by Michael R. Hamblin, James D. Carroll, and Praveen Arany. SPIE, 2014. http://dx.doi.org/10.1117/12.2038576.

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