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Journal articles on the topic 'Phenotype and genotype of enterobacter aerogenes'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Chollet, Renaud, Claude Bollet, Jacqueline Chevalier, Monique Malléa, Jean-Marie Pagès, and Anne Davin-Regli. "mar Operon Involved in Multidrug Resistance of Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 46, no. 4 (2002): 1093–97. http://dx.doi.org/10.1128/aac.46.4.1093-1097.2002.

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ABSTRACT We determined the sequence of the entire marRAB operon in Enterobacter aerogenes. It is functionally and structurally analogous to the Escherichia coli operon. The overexpression of E. aerogenes MarA induces a multidrug resistance phenotype in a susceptible strain, demonstrated by a noticeable resistance to various antibiotics, a decrease in immunodetected porins, and active efflux of norfloxacin.

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Chollet, Renaud, Jacqueline Chevalier, Claude Bollet, Jean-Marie Pages, and Anne Davin-Regli. "RamA Is an Alternate Activator of the Multidrug Resistance Cascade in Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 48, no. 7 (2004): 2518–23. http://dx.doi.org/10.1128/aac.48.7.2518-2523.2004.

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ABSTRACT Multidrug resistance (MDR) in Enterobacter aerogenes can be mediated by induction of MarA, which is triggered by certain antibiotics and phenolic compounds. In this study, we identified the gene encoding RamA, a 113-amino-acid regulatory protein belonging to the AraC-XylS transcriptional activator family, in the Enterobacter aerogenes ATCC 13048 type strain and in a clinical multiresistant isolate. Overexpression of RamA induced an MDR phenotype in drug-susceptible Escherichia coli JM109 and E. aerogenes ATCC 13048, as demonstrated by 2- to 16-fold-increased resistance to β-lactams, t

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Chevalier, Jacqueline, Jérôme Bredin, Abdallah Mahamoud, Monique Malléa, Jacques Barbe, and Jean-Marie Pagès. "Inhibitors of Antibiotic Efflux in Resistant Enterobacter aerogenes and Klebsiella pneumoniae Strains." Antimicrobial Agents and Chemotherapy 48, no. 3 (2004): 1043–46. http://dx.doi.org/10.1128/aac.48.3.1043-1046.2004.

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ABSTRACT In Enterobacter aerogenes and Klebsiella pneumoniae, efflux provides efficient extrusion of antibiotics and contributes to the multidrug resistance phenotype. One of the alkoxyquinoline derivatives studied here, 2,8-dimethyl-4-(2′-pyrrolidinoethyl)-oxyquinoline, restores noticeable drug susceptibility to resistant clinical strains. Analyses of energy-dependent chloramphenicol efflux indicate that this compound inhibits the efflux pump mechanism and improves the activity of structurally unrelated antibiotics on multidrug-resistant E. aerogenes and K. pneumoniae isolates.

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Thiolas, Aurélie, Claude Bollet, Bernard La Scola, Didier Raoult, and Jean-Marie Pagès. "Successive Emergence of Enterobacter aerogenes Strains Resistant to Imipenem and Colistin in a Patient." Antimicrobial Agents and Chemotherapy 49, no. 4 (2005): 1354–58. http://dx.doi.org/10.1128/aac.49.4.1354-1358.2005.

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ABSTRACT Enterobacter aerogenes is an agent of hospital-acquired infection that exhibits a remarkable resistance to β-lactam antibiotics during therapy. Five successive isolates of E. aerogenes infecting a patient and exhibiting a multiresistance phenotype to β-lactam antibiotics and fluoroquinolones were investigated. Among these clinical strains, four presented resistant phenotypes during successive imipenem and colistin treatments. The involved resistance mechanisms exhibited by the successive isolates were associated with alterations of the outer membrane that caused a porin decrease and l

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Charrel, R. N., J. M. Pagès, P. De Micco, and M. Mallea. "Prevalence of outer membrane porin alteration in beta-lactam-antibiotic-resistant Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 40, no. 12 (1996): 2854–58. http://dx.doi.org/10.1128/aac.40.12.2854.

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We evaluated the prevalence of impermeability as a mechanism associated with resistance against beta-lactam antibiotics in members of the family Enterobacteriaceae. During a 1-year period, 80 strains were selected from 3,110 routinely isolated strains according to their noticeable cross-resistance pattern to cephalosporins. They were tested for (i) outer membrane nonspecific porins involved in the entry of small hydrophilic molecules; (ii) the MICs of cefepime, cefotaxime, imipenem, and moxalactam; and (iii) beta-lactamase production. Immunological investigations using specific probes showed t

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Al-Doori, Zainab. "Heterospecific transcription of theEscherichia coli rpoB-3 allele in Gram-negative bacteria." Genetical Research 50, no. 2 (1987): 87–90. http://dx.doi.org/10.1017/s0016672300023478.

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SummaryrpoB is the structural gene for the β-subunit ofE. coliRNA polymerase. TherpoB-3 allele confers resistance to the antibiotic rifampicin and is unusual in being dominant to the wild-type allele. We used the plasmid pZD23, a derivative of the broad host range conjugative plasmid RP4, to introduce therpoB-3 allele into a range of bacterial species. Species belonging to the same family asE. coli(Enterobacter aerogenes, Citrobacter freundii, Hafnia alvei møller, Klebsiella pneumoniae, Salmonella typhimurium) expressedrpoB-3 to give a rifampicin resistant phenotype; this demonstrated heterosp

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Gayet, Stéphane, Renaud Chollet, Gérard Molle, Jean-Marie Pagès, and Jacqueline Chevalier. "Modification of Outer Membrane Protein Profile and Evidence Suggesting an Active Drug Pump in Enterobacter aerogenes Clinical Strains." Antimicrobial Agents and Chemotherapy 47, no. 5 (2003): 1555–59. http://dx.doi.org/10.1128/aac.47.5.1555-1559.2003.

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ABSTRACT Two clinical strains of Enterobacter aerogenes that exhibited phenotypes of multiresistance to β-lactam antibiotics, fluoroquinolones, chloramphenicol, tetracycline, and kanamycin were investigated. Both strains showed a porin pattern different from that of a susceptible strain, with a drastic reduction in the amount of the major porin but with an apparently conserved normal structure (size and immunogenicity), together with overproduction of two known outer membrane proteins, OmpX and LamB. In addition, the full-length O-polysaccharide phenotype was replaced by a semirough Ra phenoty

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Bonnet, R., J. L. M. Sampaio, R. Labia та ін. "A Novel CTX-M β-Lactamase (CTX-M-8) in Cefotaxime-ResistantEnterobacteriaceae Isolated in Brazil". Antimicrobial Agents and Chemotherapy 44, № 7 (2000): 1936–42. http://dx.doi.org/10.1128/aac.44.7.1936-1942.2000.

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ABSTRACT To estimate the diversity of extended-spectrum β-lactamases in Brazil, 18 strains from different species of the familyEnterobacteriaceae exhibiting a positive double-disk synergy test were collected by a clinical laboratory from several hospitals in Rio de Janeiro, Brazil, in 1996 and 1997. Four strains (Proteus mirabilis, Enterobacter cloacae,Enterobacter aerogenes, and Citrobacter amalonaticus) hybridized with a 550-bp CTX-M probe. The P. mirabilis strain produced a CTX-M-2 enzyme. The E. cloacae, E. aerogenes, and C. amalonaticus isolates harbored a bla gene which was identified by

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Yousuf, Farzana, Ruqaiyyah Siddiqui, and Naveed Khan. "Acanthamoeba castellanii of the T4 genotype is a potential environmental host for Enterobacter aerogenes and Aeromonas hydrophila." Parasites & Vectors 6, no. 1 (2013): 169. http://dx.doi.org/10.1186/1756-3305-6-169.

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Tzelepi, Eva, Panagiota Giakkoupi, Danai Sofianou, Veneta Loukova, Anastassia Kemeroglou та Athanassios Tsakris. "Detection of Extended-Spectrum β-Lactamases in Clinical Isolates of Enterobacter cloacae andEnterobacter aerogenes". Journal of Clinical Microbiology 38, № 2 (2000): 542–46. http://dx.doi.org/10.1128/jcm.38.2.542-546.2000.

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The aim of the present study was to investigate the frequency of extended-spectrum β-lactamases (ESBLs) in a consecutive collection of clinical isolates of Enterobacter spp. The abilities of various screening methods to detect ESBLs in enterobacters were simultaneously tested. Among the 68 consecutive isolates (56Enterobacter cloacae and 12 Enterobacter aerogenes isolates) that were analyzed for β-lactamase content, 21 (25 and 58%, respectively) possessed transferable ESBLs with pIs of 8.2 and phenotypic characteristics of SHV-type enzymes, 8 (14.3%) of the E. cloacae isolates produced a previ

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Han, Kook-Il, Eui-Gil Jung, Bharat Bhusan Patnaik, et al. "Antibacterial and Antioxidant Activities of Leaf Extracts from Juglans sinensis, and its Phenolic Compositions." Natural Product Communications 12, no. 11 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201138.

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The beneficial properties of walnut depend on climate, genotype, and farming practices. We investigated the antibacterial and antioxidant activities of Juglans sinensis Dode cultivars grown in South Korea. Antibacterial activities were assessed using the minimum inhibitory concentration method and antioxidant activities using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Ethyl acetate and chloroform extracts of J. sinensis leaves showed the highest antibacterial activity against Staphylococcus aureus SG511, Klebsiella aeroge

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Clark, Justin, and David Burgess. "Difference in Susceptibility Between Carbapenemase- and Non–Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae." Antimicrobial Stewardship & Healthcare Epidemiology 1, S1 (2021): s70. http://dx.doi.org/10.1017/ash.2021.136.

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Background: Carbapenem-resistant Enterobacteriaceae (CRE) remain among the most urgent infectious threats according to the CDC Threats Reports. Although focus has often been placed on carbapenemase-producing phenotypes, there is increasing interest in distinguishing the optimal treatment and outcomes of carbapenemase-producing (CP) and non–carbapenemase-producing (NCP) CRE. We compare antimicrobial susceptibility patterns between CP-CRE and NCP-CRE isolated from patients at our academic medical center. Methods: All CRE isolates of Enterobacter cloacae, Escherichia coli, Klebsiella aerogenes, K

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Coudeyras, Sophie, Laurence Nakusi, Nicolas Charbonnel, and Christiane Forestier. "A Tripartite Efflux Pump Involved in Gastrointestinal Colonization by Klebsiella pneumoniae Confers a Tolerance Response to Inorganic Acid." Infection and Immunity 76, no. 10 (2008): 4633–41. http://dx.doi.org/10.1128/iai.00356-08.

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ABSTRACT The colonization of the gastrointestinal tract of patients by the opportunistic gram-negative bacillus Klebsiella pneumoniae generally occurs prior to the development of nosocomial infections. Mutant strain C-81 was isolated owing to its reduced capacity to colonize the digestive tract in a murine model following transposon mutagenesis (N. Maroncle, D. Balestrino, C. Rich, and C. Forestier, Infect. Immun. 70:4729-4734, 2002). Nucleotide sequence analysis showed that the transposon had inserted into the first open reading frame, eefA, of a three-gene locus (eefABC) whose homologue enco

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Zhanel, George G., Melanie DeCorby, Heather Adam, et al. "Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2008)." Antimicrobial Agents and Chemotherapy 54, no. 11 (2010): 4684–93. http://dx.doi.org/10.1128/aac.00469-10.

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ABSTRACT A total of 5,282 bacterial isolates obtained between 1 January and 31 December 31 2008, inclusive, from patients in 10 hospitals across Canada as part of the Canadian Ward Surveillance Study (CANWARD 2008) underwent susceptibility testing. The 10 most common organisms, representing 78.8% of all clinical specimens, were as follows: Escherichia coli (21.4%), methicillin-susceptible Staphylococcus aureus (MSSA; 13.9%), Streptococcus pneumoniae (10.3%), Pseudomonas aeruginosa (7.1%), Klebsiella pneumoniae (6.0%), coagulase-negative staphylococci/Staphylococcus epidermidis (5.4%), methicil

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Kiratisin, Pattarachai, та Arunocha Henprasert. "Resistance phenotype-genotype correlation and molecular epidemiology of Citrobacter, Enterobacter, Proteus, Providencia, Salmonella and Serratia that carry extended-spectrum β-lactamases with or without plasmid-mediated AmpC β-lactamase genes in Thailand". Transactions of the Royal Society of Tropical Medicine and Hygiene 105, № 1 (2011): 46–51. http://dx.doi.org/10.1016/j.trstmh.2010.07.010.

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Zhanel, George G., Mel DeCorby, Nancy Laing, et al. "Antimicrobial-Resistant Pathogens in Intensive Care Units in Canada: Results of the Canadian National Intensive Care Unit (CAN-ICU) Study, 2005-2006." Antimicrobial Agents and Chemotherapy 52, no. 4 (2008): 1430–37. http://dx.doi.org/10.1128/aac.01538-07.

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ABSTRACT Between 1 September 2005 and 30 June 2006, 19 medical centers collected 4,180 isolates recovered from clinical specimens from patients in intensive care units (ICUs) in Canada. The 4,180 isolates were collected from 2,292 respiratory specimens (54.8%), 738 blood specimens (17.7%), 581 wound/tissue specimens (13.9%), and 569 urinary specimens (13.6%). The 10 most common organisms isolated from 79.5% of all clinical specimens were methicillin-susceptible Staphylococcus aureus (MSSA) (16.4%), Escherichia coli (12.8%), Pseudomonas aeruginosa (10.0%), Haemophilus influenzae (7.9%), coagula

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Bukina, YV, AM Kamyshny, and NN Polishchuk. "DETERMINATION OF THE SPECTRUM OF ANTIBIOTIC RESISTANCE GENES HAVE PHENOTYPIC RESISTANT STRAINS OF PARIETAL INTESTINAL MICROBIOTA IN RATS BY RT-PCR." Annals of Mechnikov Institute, no. 2 (November 18, 2016): 21–27. https://doi.org/10.5281/zenodo.167489.

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Introduction. The problem of formation of bacterial resistance to glycopeptides and beta-lactam antibiotics (cephalosporins and carbapenems) are used worldwide for the treatment of severe community acquired and nosocomial infections, especially caused by polymicrobial flora has become global and is a major factor limiting the effectiveness of antibiotic therapy. In this regard, the study of genetic microbial resistance determinants allows not only to carry out an effective antibiotic therapy, but also to identify two main processes leading to the development of epidemiologically significant ev

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Mayank Gangwar, and Snehasis Jana. "Characterization of Phenotype and Genotype of Biofield Treated Enterobacter aerogenes." Translational Medicine 5, no. 4 (2015). https://doi.org/10.4172/2161-1025.1000155.

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Enterobacter aerogenes (E. aerogenes) has been commonly described as a versatile opportunistic pathogen in hospital infections. The aim of the present work was to evaluate the impact of biofield treatment on E. aerogenes for its phenotypic and genotypic characteristics. E. aerogenes bearing ATCC 13048 (American Type Culture Collection) was procured from Bangalore Genei, in sealed pack and divided into control and treated groups. Treated group was subjected to Mr. Trivedi’s biofield treatment and analyzed for antimicrobial susceptibility, minimum inhibitory concentration (MIC), biochemica

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Mayank Gangwar, and Snehasis Jana. "Characterization of Phenotype and Genotype of Biofield Treated Enterobacter aerogenes." Translational Medicine 5, no. 4 (2015). https://doi.org/10.5281/zenodo.167153.

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Enterobacter aerogenes (E. aerogenes) has been commonly described as a versatile opportunistic pathogen in hospital infections. The aim of the present work was to evaluate the impact of biofield treatment on E. aerogenes for its phenotypic and genotypic characteristics. E. aerogenes bearing ATCC 13048 (American Type Culture Collection) was procured from Bangalore Genei, in sealed pack and divided into control and treated groups. Treated group was subjected to Mr. Trivedi’s biofield treatment and analyzed for antimicrobial susceptibility, minimum inhibitory concen

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Trivedi, Mahendra, Alice Branton, Dahryn Trivedi, and Gopal Nayak. "Characterization of Phenotype and Genotype of Biofield Treated Enterobacter aerogenes." OMICS International, September 12, 2015. https://doi.org/10.5281/zenodo.813426.

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Enterobacter aerogenes (E. aerogenes) has been commonly described as a versatile opportunistic pathogen in hospital infections. The aim of the present work was to evaluate the impact of biofield treatment on E. aerogenes for its phenotypic and genotypic characteristics. E. aerogenes bearing ATCC 13048 (American Type Culture Collection) was procured from Bangalore Genei, in sealed pack and divided into control and treated groups. Treated group was subjected to Mr. Trivedi's biofield treatment and analyzed for antimicrobial susceptibility, minimum inhibitory concentration (MIC), biochemical reac

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Jana, Snehasis, Mahendra Kumar Trivedi, and Alice Branton. "Characterization of Phenotype and Genotype of Biofield Treated Enterobacter aerogenes." Translational Medicine 05, no. 04 (2015). http://dx.doi.org/10.4172/2161-1025.1000155.

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Wesevich, Austin, Granger Sutton, Felicia Ruffin, et al. "Newly Named Klebsiella aerogenes (formerly Enterobacter aerogenes) Is Associated with Poor Clinical Outcomes Relative to Other Enterobacter Species in Patients with Bloodstream Infection." Journal of Clinical Microbiology 58, no. 9 (2020). http://dx.doi.org/10.1128/jcm.00582-20.

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ABSTRACT Enterobacter aerogenes was recently renamed Klebsiella aerogenes. This study aimed to identify differences in clinical characteristics, outcomes, and bacterial genetics among patients with K. aerogenes versus Enterobacter species bloodstream infections (BSI). We prospectively enrolled patients with K. aerogenes or Enterobacter cloacae complex (Ecc) BSI from 2002 to 2015. We performed whole-genome sequencing (WGS) and pan-genome analysis on all bacteria. Overall, 150 patients with K. aerogenes (46/150 [31%]) or Ecc (104/150 [69%]) BSI were enrolled. The two groups had similar baseline

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Davin-Regli, Anne, Jean-Philippe Lavigne, and Jean-Marie Pagès. "Enterobacter spp.: Update on Taxonomy, Clinical Aspects, and Emerging Antimicrobial Resistance." Clinical Microbiology Reviews 32, no. 4 (2019). http://dx.doi.org/10.1128/cmr.00002-19.

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SUMMARY The genus Enterobacter is a member of the ESKAPE group, which contains the major resistant bacterial pathogens. First described in 1960, this group member has proven to be more complex as a result of the exponential evolution of phenotypic and genotypic methods. Today, 22 species belong to the Enterobacter genus. These species are described in the environment and have been reported as opportunistic pathogens in plants, animals, and humans. The pathogenicity/virulence of this bacterium remains rather unclear due to the limited amount of work performed to date in this field. In contrast,

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Malek, Alexander, Josselin Abi Chebl, Hadi Younes, Jacques Choucair, and Nadim Azar. "Carbapenemase typing and resistance profile of Enterobacteriaceae with reduced sensitivity to carbapenems in a Middle Eastern tertiary care center." International Arabic Journal of Antimicrobial Agents 12, no. 1 (2022). http://dx.doi.org/10.3823/863.

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Objective: nowadays resistant bacteria represent worldwide a public health problem leading in some cases to a stalemate without any possible treatment. Therefore early detection and identification of carbapenemase producing gram-negative bacteria (GNB) is of crucial importance. Consequently we conducted a study in a tertiary care hospital to analyze the resistance phenotype of the carbapenem resistant GNB (CRGNB). Methods: we collected all the CRGNB from September 2014 till January 2016, we took randomly 40/126 strains and performed a sensitivity test in addition to a real time multiplex PCR t

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Trivedi, Mahendra. "Evaluation of Antibiogram, Genotype and Phylogenetic Analysis of Biofield Treated Nocardia otitidis." www.omicsgroup.org, September 9, 2015. https://doi.org/10.5281/zenodo.813523.

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Nocardiosis is a soil-borne aerobic infection caused by Nocardia species commonly affects the respiratory tract. Nocardia otitidis (N. otitidis) is the key organism for non-mycobacterial tuberculosis. The current study was attempted to investigate the effect of Mr. Trivedi's biofield energy treatment on N. otitidis and analyzed for antimicrobial susceptibility pattern, minimum inhibitory concentration (MIC), DNA polymorphism by Random Amplified Polymorphic DNA (RAPD) and 16S rDNA sequencing. The strain of N. otitidis (ATCC 14630) was divided into two parts, control and treated. Antimicrobial s

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Sambhu Charan Mondal, and Snehasis Jana. "Evaluation of Antibiogram, Genotype and Phylogenetic Analysis of Biofield Treated Nocardia otitidis." Biological Systems: Open Access 4, no. 2 (2015). https://doi.org/10.4172/2329-6577.1000143.

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Nocardiosis is a soil-borne aerobic infection caused by Nocardia species commonly affects the respiratory tract. Nocardia otitidis (N. otitidis) is the key organism for non-mycobacterial tuberculosis. The current study was attempted to investigate the effect of Mr. Trivedi’s biofield energy treatment on N. otitidis and analyzed for antimicrobial susceptibility pattern, minimum inhibitory concentration (MIC), DNA polymorphism by Random Amplified Polymorphic DNA (RAPD) and 16S rDNA sequencing. The strain of N. otitidis (ATCC 14630) was divided into two parts, control and treated. Antimicro

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Sambhu Charan Mondal, and Snehasis Jana. "Evaluation of Antibiogram, Genotype and Phylogenetic Analysis of Biofield Treated Nocardia otitidis." Biological Systems: Open Access 4, no. 2 (2015). https://doi.org/10.5281/zenodo.167521.

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Nocardiosis is a soil-borne aerobic infection caused by Nocardia species commonly affects the respiratory tract. Nocardia otitidis (N. otitidis) is the key organism for non-mycobacterial tuberculosis. The current study was attempted to investigate the effect of Mr. Trivedi’s biofield energy treatment on N. otitidis and analyzed for antimicrobial susceptibility pattern, minimum inhibitory concentration (MIC), DNA polymorphism by Random Amplified Polymorphic DNA (RAPD) and 16S rDNA sequencing. The strain of N. otitidis (ATCC 14630) was divided into t

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Delplanque, Marion, Nicolas Benech, Nathalie Rolhion, et al. "Gut microbiota alterations are associated with phenotype and genotype in familial Mediterranean fever." Rheumatology, July 4, 2023. http://dx.doi.org/10.1093/rheumatology/kead322.

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Abstract Objectives Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease associated with MEFV mutations. Disease phenotype and response to treatment vary from one patient to another despite similar genotype suggesting the role of environmental factors. We analyze the gut microbiota of a large cohort of FMF patients in relation to disease characteristics. Methods The gut microbiota of 119 FMF patients and 61 healthy controls was analyzed using 16 s rRNA gene sequencing. Associations between bacterial taxa, clinical characteristics and genotypes were evaluated

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Liao, Qiaoming, Han Tao, Yali Li, Yi Xu, and Hui-Li Wang. "Evaluation of Structural Changes and Molecular Mechanism Induced by High Hydrostatic Pressure in Enterobacter sakazakii." Frontiers in Nutrition 8 (September 23, 2021). http://dx.doi.org/10.3389/fnut.2021.739863.

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The contamination of infant milk and powder with Enterobacter sakazakii poses a risk to human health and frequently caused recalls of affected products. This study aims to explore the inactivation mechanism of E. sakazakii induced by high hydrostatic pressure (HHP), which, unlike conventional heat treatment, is a nonthermal technique for pasteurization and sterilization of dairy food without deleterious effects. The mortality of E. sakazakii under minimum reaction conditions (50 MPa) was 1.42%, which was increased to 33.12% under significant reaction conditions (400 MPa). Scanning electron mic

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Abdelaziz, Neveen A. "Phenotype-genotype correlations among carbapenem-resistant Enterobacterales recovered from four Egyptian hospitals with the report of SPM carbapenemase." Antimicrobial Resistance & Infection Control 11, no. 1 (2022). http://dx.doi.org/10.1186/s13756-022-01061-7.

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Abstract Background Carbapenem-resistant Enterobacterales (CRE), currently listed by the World Health Organization (WHO) as top priority critical pathogens, are a major global menace to human health. In low- and middle-income countries (LMICs) the threat is mounting fueled by selective pressures caused by antibiotic abuse and inadequate diagnostic resources. Methods This study phenotypically and genotypically characterized carbapenem resistance among 115 Enterobacterales isolates including 76 Klebsiella (K.) pneumoniae, 19 Escherichia (E.) coli, 14 Shigella (S.) sonnei, 5 Enterobacter (E.) clo

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Díaz-Gavidia, Constanza, Carla Barría, Lina Rivas, et al. "Isolation of Ciprofloxacin and Ceftazidime-Resistant Enterobacterales From Vegetables and River Water Is Strongly Associated With the Season and the Sample Type." Frontiers in Microbiology 12 (September 14, 2021). http://dx.doi.org/10.3389/fmicb.2021.604567.

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The dissemination of antibiotic-resistant bacteria (ARB) from water used for crop irrigation to vegetables is poorly studied. During a year, five farmer markets in a city in Central Chile were visited, and 478 vegetable samples (parsleys, corianders, celeries, lettuces, chards, and beets) were collected. Simultaneously, 32 water samples were collected from two rivers which are used to irrigate the vegetables produced in the area. Resistant Enterobacterales were isolated and identified. Colistin resistance gene mcr-1 and extended spectrum β-lactamases (ESBL) were molecularly detected. The assoc

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Zelendova, Marketa, Costas C. Papagiannitsis, Petra Sismova, et al. "Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic." Frontiers in Microbiology 14 (April 27, 2023). http://dx.doi.org/10.3389/fmicb.2023.1147846.

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The occurrence of colistin resistance has increased rapidly among Enterobacterales around the world. We performed a national survey of plasmid-mediated colistin resistance in human clinical isolates through a retrospective analysis of samples from 2009 to 2017 and a prospective sampling in 2018–2020. The aim of this study was to identify and characterize isolates with mcr genes from various regions of the Czech Republic using whole genome sequencing (WGS). Of all 1932 colistin-resistant isolates analyzed, 73 (3.8%) were positive for mcr genes. Most isolates carried mcr-1 (48/73) and were ident

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Koch, Rachelle E., Jackson Barth, Andrew E. Clark, et al. "Antibiotic resistance genotype, phenotype, and clinical outcomes in patients with Gram-negative infections at Rabin Medical Center in Israel." Microbiology Spectrum, November 27, 2024. http://dx.doi.org/10.1128/spectrum.00383-24.

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ABSTRACT Antibiotic resistance is a major cause of morbidity and mortality. However, a better understanding of the relationship between bacterial genetic markers, phenotypic resistance, and clinical outcomes is needed. We performed whole-genome sequencing on five medically important pathogens ( Acinetobacter baumannii , Enterobacter cloacae , Escherichia coli , Klebsiella pneumoniae , and Pseudomonas aeruginosa ) to investigate how resistance genes impact patient outcomes. A total of 168 isolates from 162 patients with Gram-negative infections admitted to Beilinson Hospital at Rabin Medical Ce

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Santajit, Sirijan, Witawat Tunyong, Thida Kong-Ngoen, et al. "Evaluation of bla _OXA-48-like point mutation carbapenemase-producing Enterobacterales in Prapokklao Hospital, Thailand." Microbiology Spectrum, October 17, 2024. http://dx.doi.org/10.1128/spectrum.00198-24.

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ABSTRACT Carbapenemase-producing Enterobacterales (CPE) isolates increasingly carry oxacillinase-48 (OXA-48)-like enzymes encoded by bla OXA-48-like , which can confer high levels of carbapenem resistance. This aims to determine the prevalence of CPE and genetic variation among bla OXA-48-like -carrying isolates recovered from Prapokklao Hospital in Chanthaburi Province, Thailand in 2016–2017. In total, 122 carbapenem-resistant Enterobacterales (CRE) isolates were recovered from clinical samples. CRE were evaluated using standard biochemical tests and MIC test strips. Carbapenemase production

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Costa, Carolina F. F. A., Ana Merino-Ribas, Catarina Ferreira, et al. "Characterization of Oral Enterobacteriaceae Prevalence and Resistance Profile in Chronic Kidney Disease Patients Undergoing Peritoneal Dialysis." Frontiers in Microbiology 12 (December 14, 2021). http://dx.doi.org/10.3389/fmicb.2021.736685.

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Abstract:

Chronic Kidney Disease (CKD) is a growing public-health concern worldwide. Patients exhibit compromised immunity and are more prone to infection than other populations. Therefore, oral colonization by clinically relevant members of the Enterobacteriaceae family, major agents of both nosocomial and dialysis-associated infections with frequent prevalence of antibiotic resistances, may constitute a serious risk. Thus, this study aimed to assess the occurrence of clinically relevant enterobacteria and their antibiotic resistance profiles in the oral cavity of CKD patients undergoing peritoneal dia

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