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1

Fu, Jun-Dan, and Yi-Hang Wen. "2-[4-(Carboxymethyl)phenoxy]acetic acid." Acta Crystallographica Section E Structure Reports Online 67, no. 1 (December 18, 2010): o167. http://dx.doi.org/10.1107/s1600536810051810.

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2

GUO, TAO, XIAOLI WANG, HAIFENG WANG, YUFEN HU, SHIYONG ZHANG, and RUSONG ZHAO. "Determination of Phenoxy Acid Herbicides in Cereals Using High-Performance Liquid Chromatography–Tandem Mass Spectrometry." Journal of Food Protection 82, no. 7 (June 24, 2019): 1160–65. http://dx.doi.org/10.4315/0362-028x.jfp-18-558.

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ABSTRACTAn effective method for determination of multiple residues of phenoxy acid herbicides in cereals was developed. A QuEChERS (quick, easy, cheap, effective, rugged, and safe) technique coupled with high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) was optimized for the analysis of phenoxy acid herbicides in rice, corn, and wheat. The limits of detection in the experiment were 0.0500 μg/kg for 4-(2,4-dichlorophenoxy)acetic acid, (4-chloro-2-methylphenoxy)acetic acid, (2,4,5-trichlorophenoxy)acetic acid, and 2-(2,4-dichlorophenoxy)propionic acid and 0.300 μg/kg for 4-(2,4-dichlorophenoxy)butyric acid and 3,6-dichloro-2-methoxybenzoic acid. The relative standard deviation of intraday and interday precision for the six phenoxy acid herbicides was less than 6.61%, and accuracy was 96.3 to 107%. Extraction recovery for phenoxy acid herbicides was 73.8 to 115%, with relative standard deviations of less than 12.1% at three spiking levels (1.00, 4.00, and 20.0 μg/kg). These results indicate that QuEChERS sample preparation with HPLC-MS/MS analysis is a rapid, reliable, highly sensitive, and specific tool for the determination of phenoxy acid herbicide residues in cereals.HIGHLIGHTS
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3

Adohi-Krou, A., V. Coulibaly, D. Sissouma, A. J. Tenon, and F. Porcher. "Crystal structure of 2,4-dimethyl-phenoxy-2-acetic acid, C10H12O3." Zeitschrift für Kristallographie - New Crystal Structures 220, no. 1-4 (April 2005): 167–68. http://dx.doi.org/10.1524/ncrs.2005.220.14.167.

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4

Liu, Bao-Yu, Zheng Liu, and Guo-Rui Wang. "2-(2-{[2-(2-Pyridylcarbonyl)hydrazono]methyl}phenoxy)acetic acid." Acta Crystallographica Section E Structure Reports Online 66, no. 1 (December 4, 2009): o26. http://dx.doi.org/10.1107/s160053680905082x.

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5

Xia, Jin Hong, Bao Yu Liu, and Zheng Liu. "2-(2-{[2-(4-Pyridylcarbonyl)hydrazinylidene]methyl}phenoxy)acetic acid." Acta Crystallographica Section E Structure Reports Online 66, no. 6 (May 15, 2010): o1341. http://dx.doi.org/10.1107/s1600536810017083.

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6

Kuziv, S., O. Shablykina, and V. Khilya. "METHYL ESTER OF {2-[2-CYANO-2-(4-NITROPHENYL)VINYL]PHENOXY}ACETIC ACID IN REDUCTION PROCESSES." Bulletin of Taras Shevchenko National University of Kyiv. Chemistry, no. 2(54) (2017): 71–73. http://dx.doi.org/10.17721/1728-2209.2017.2(54).14.

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3-(Het)aryl-3-(2-alkoxyphenyl)acrylonitriles are very practical polyfunctional molecules for organic synthesis; in particular difficult objects with near placed active groups can be easy obtained by the reduction of 3-(het)aryl-3-(2-alkoxyphenyl)acrylonitriles fragments. But now only reduction of activated C=C bond in such molecules mostly investigated. Previously it was shown by us that the action of sodium borohydride on esters of {2-[2-cyano-2-(4-nitrophenyl)vinyl]phenoxy}acetic acid caused not only saturation of C=C bond but also reduction of ester group to alcohol. So the results of reduction of 3-(het)aryl-3-(2-alkoxyphenyl)acrylonitriles can be more interest when other electrophilic fragment presents in molecule. And the aim of current work is the investigation of methyl ester of {2-[2-cyano-2-(4-nitrophenyl)vinyl]phenoxy}acetic acid behaviour in different reductive medium. Because of the very high electrophylity of observed molecule it's unfeasible to obtain good result in reactions with strong nucleophyles or with chemical reduction agents; that's why the hydrogenation in mild condition was used on the first step. It was found that the nitro group and the activated C=C bond were reducted simultaneously by H2 at 1.2 atm presure and room temperature with Pd/C catalizing; so methyl ester of {2-[2-(4-aminophenyl)-2-cyanoethyl]phenoxy}acetic acid was formed. Further hydrogenation took place on higher H2 presure (80 atm); and as a result of the saturation of C≡N bond methyl ester of {2-[3-amino-2-(4-aminophenyl)propyl]phenoxy}acetic acid creation occurred. The last compound can be transformed into 2-{2-[3-amino-2-(4-aminophenyl)propyl]phenoxy}ethanol by the LiAlH4 action. Such interesting structure also can be synthetized through the reduction of 3-[2-(2-hydroxyethoxy)phenyl]-2-(4-nitrophenyl)propionitrile that was obtained earlier: in the first step hydrogenation (1.2 atm H2) produced 3-[2-(2-hydroxyethoxy)phenyl]-2-(4-aminophenyl)propionitrile which nitrile group was reducted by LiAlH4 in the second step.
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7

Belmouden, Moustapha, Ali Assabbane, and Yhia Ait Ichou. "Adsorption characteristics of a phenoxy acetic acid herbicide on activated carbon." Journal of Environmental Monitoring 2, no. 3 (2000): 257–60. http://dx.doi.org/10.1039/a909357e.

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8

Fun, Hoong-Kun, Tze Shyang Chia, Ahmed M. Alafeefy, and Hatem A. Abdel-Aziz. "2-{2-[(E)-(2-Benzoylhydrazin-1-ylidene)methyl]phenoxy}acetic acid." Acta Crystallographica Section E Structure Reports Online 68, no. 7 (June 30, 2012): o2260—o2261. http://dx.doi.org/10.1107/s1600536812028735.

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9

Shokol, Т., N. Gorbulenko, and V. Khilya. "SYNTHESIS OF 7-HYDROXY-2,8-DIMETHYL-4-OXO-3-PHENOXY-4H-6-CHROMENECARBALDEHYDE." Bulletin of Taras Shevchenko National University of Kyiv. Chemistry, no. 1(55) (2018): 54–57. http://dx.doi.org/10.17721/1728-2209.2018.1(55).13.

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Ortho-hydroxyformylchromones are convenient syntones for the construction of linear and angular hetarenochromones. Usually, 7-hydroxy-6-formylchromones were synthesized by oxidation of natural linear furochromones: visnagin and kellin and their synthetic analogues. The Duff reaction, which is the formylation of phenols in the ortho-position by heating with hexamethylenetetramine followed by acidic hydrolysis of intermediate imine, was also used to convert 7-hydroxychromones into 7-hydroxy-6-formylchromones, but in this case there were some difficulties because of the passivity of position 6 in 7-hydroxychromones compared to position 8 to the electrophilic attack. Thus, for the preparation of 7-hydroxy-6-formylchromones, it is necessary to use 8-substituted derivatives and to provide formylation for a long time.A method for the synthesis of 7-hydroxy-6-formylchromones based on 8-substituted 7-hydroxy-6-dialkylaminomethylchromones and hexamethylenetetramine was developed using the Duff reaction conditions. This method was demonstrated on the synthesis of 7-hydroxy-2,8-dimethyl-4-oxo-3-phenoxy-4H-6-chromenecarbaldehyde from 6-dimethylaminomethyl-7-hydroxy-2,8-dimethyl-3-phenoxy-4H-4-chromenone and hexamethylenetetramine in glacial acetic acid at reflux. It should be noted that when carrying out this reaction under heating on a water bath with subsequent hydrochloric acid hydrolysis only Mannich basehydrochloride was isolated from the reaction mixture. The starting 6-dimethylaminomethyl-7-hydroxy-2,8-dimethyl-3-phenoxy-4H-4-chromenone was synthesized from 1-(2,4-dihydroxy-3-methylphenyl)-2-phenoxyethanone in three steps. Acylation of the latter with acetic anhydride in the presence of triethylamine followed by condensation afforded 2,8-dimethyl-4-оxо-3-phenoxy-4Н-7-chromenylаcetate. Subsequent removal of acetyl protection resulted in 7-hydroxy-2,8-dimethyl-3-phenoxy-4H-4-chromenone, which on introduction into the Mannich reaction with bisdimethylaminomethane in dioxane gave rise to the desired 6-dimethylaminomethyl derivative.
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10

Akhter, S., T. Mostarin, K. Khatun, F. Akhter, and A. Parvin. "Effects of Plant Growth Regulator on Yield and Economic Benefit of Sweet Pepper (Capsicum annum L.)." Agriculturists 16, no. 02 (December 22, 2018): 58–64. http://dx.doi.org/10.3329/agric.v16i02.40343.

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The experiment was conducted in the Horticultural Farm of Sher-e-Bangla Agricultural University, Dhaka, Bangladesh. Plant growth regulators were applied which had significant effect on yield of sweet pepper (Capsicum annum L.). The experiment consisted of two factors. Factor A: Plant growth regulators (four levels) as G0: Control, G1: Gibberellic Acid (GA3) @ 30 ppm, G2: 4-Chloro Phenoxy Acetic Acid (4-CPA) @ 45 ppm and G3: 4-Chloro Phenoxy Acetic Acid (4-CPA) @ 45 ppm + Gibberellic Acid (GA3) @ 30 ppm and Factor B: Number of spray (three levels) as N0: Control (no spray), N1: two spray, N2: three spray. In case of plant growth regulators, the highest yield (27.77 t/ha) was found from G3 treatment, whereas the lowest (18.87 t/ha) was from G0 treatment. For number of spray the maximum yield (26.0 t/ha) was recorded from N2 treatment, while the minimum yield (19.87 t/ha) was from N0 treatment. The results indicated that the highest yield (31.8 t/ha) was observed from G3N2 treatment combination, while the lowest yield (17.5 t/ha) was from G0N0 treatment combination. Due to combined effect, the highest yield (31.8 t/ha) with net income (Tk/ha 1416558) and BCR (2.46) was observed from G3N2 treatment combination, while the lowest yield (17.5 t/ha) with net income (Tk/ha 433045) and BCR (1.49) from G0N0 treatment combination. Thus, three times spray with (4- Chloro Phenoxy Acetic Acid + Gibberellic Acid) may be recommended for achieving the higher growth, yield and economic benefit of sweet pepper. The Agriculturists 2018; 16(2) 58-64
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11

Ma, Yangyang, Zhongtian Du, Fei Xia, Jiping Ma, Jin Gao, and Jie Xu. "Mechanistic studies on the VO(acac)2-catalyzed oxidative cleavage of lignin model compounds in acetic acid." RSC Advances 6, no. 111 (2016): 110229–34. http://dx.doi.org/10.1039/c6ra23486k.

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Selective aerobic oxidation has provided a promising approach for breaking lignin into smaller aromatics. Here, the reaction pathway of VO(acac)2-catalyzed oxidation of lignin model 2-phenoxy-1-phenylethanol in acetic acid was studied.
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12

Laddha, Purushottam R., and Kailash R. Biyani. "Synthesis and Biological Evaluation of Novel Schiff Bases of Aryloxy Moiety." Journal of Drug Delivery and Therapeutics 9, no. 5-s (October 15, 2019): 44–49. http://dx.doi.org/10.22270/jddt.v9i5-s.3635.

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Schiff's bases are condensation products of primary amines with carbonyl compounds. Schiff bases (imines) possess wide variety of biological activities that include antibacterial and antifungal activity. In present work, Schiff bases from 3,5- Dimethoxyphenol (aryloxy moiety) as starting material synthesized. Esterification of 3,5- Dimethoxyphenol led to formation of (3,5-Dimethoxy-phenoxy)-acetic acid ethyl ester (1). (3,5-Dimethoxy-phenoxy)-acetic acid hydrazide (2) is derived from Compound (1) by hydrazination. Compound (2) was reacted with different aromatic aldehydes to yield novel imines or Schiff bases (3A-I). The newly synthesized compounds were characterized on the basis of spectral studies and evaluated for antibacterial and antifungal activities. All the synthesized compounds had shown antibacterial and antifungal activity. Schiff bases 3C, 3D, 3E and 3I had shown good antimicrobial activity among all newly synthesized compounds. Keywords: Schiff base, aryloxy moiety, imines
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13

RANGANATHA, V. Lakshmi, N. VINUTHA, Shaukath A. KHANUM, Sumati ANTHAL, D. REVANNASIDDAIAH, Rajnikant, and Vivek K. GUPTA. "Crystal Structure of (4-Benzoyl-2-methyl-phenoxy)-acetic acid ethyl ester." X-ray Structure Analysis Online 28 (2012): 27–28. http://dx.doi.org/10.2116/xraystruct.28.27.

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14

Anbarasu, K., and K. K. Ilavenil. "Synthesis, Characterization and Pharmacological Activity of Phenoxy Acetic Acid and Pyrazinium Chlorochromate." Asian Journal of Chemistry 30, no. 10 (2018): 2238–40. http://dx.doi.org/10.14233/ajchem.2018.21417.

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15

yar, Mohammad Shahar, Anees Ahmad Siddiqui, and Mohamed Ashraf Ali. "Synthesis and evaluation of phenoxy acetic acid derivatives as anti-mycobacterial agents." Bioorganic & Medicinal Chemistry Letters 16, no. 17 (September 2006): 4571–74. http://dx.doi.org/10.1016/j.bmcl.2006.06.021.

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16

Ienascu, Ioana M. c., Alfa X. Lupea, Iuliana M. Popescu, Stefan Th Tomas, and Alina D. Zamfir. "Synthesis and Characterization of Some New 2-Hydroxy-N-(3-Trifluoromethyl-Phenyl)-Benzamide Derivatives." Revista de Chimie 59, no. 1 (February 9, 2008): 56–60. http://dx.doi.org/10.37358/rc.08.1.1707.

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In the reaction between 2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide and chloro-acetic acid ethyl ester, [2-(3-trifluoromethyl-phenylcarbamoyl)-phenoxy]-acetic acid ethyl ester was obtained. The ethyl ester was condensed with hydrazine giving 2-hydrazinocarbonylmethoxy-N-(3-trifluoromethyl-phenyl)-benzamide. This hydrazide is considered the key intermediate for the synthesis of new compounds. So, in the reaction between hydrazide and chloro-substituted benzaldehydes hydrazones were obtained. In order to establish their structures, all new synthesized compounds were analyzed by modern physico-chemical methods (FTIR, 1H-NMR, 13C-NMR, MS).
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17

Farsa, Oldřich, Milan Dockal, Jana Kováciková, and Mária Benesová. "Synthesis of 2-{[2-(2-oxo-1-azacycloalkyl)acetamido]phenoxy}acetic acids and their activity as aminopeptidase M inhibitors." Journal of the Serbian Chemical Society 73, no. 8-9 (2008): 771–80. http://dx.doi.org/10.2298/jsc0809771f.

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A series of 9 phenoxyacetic acids substituted in the o-, m-, and p-position of benzene ring with 2-(2-oxo-1-azacycloalkyl)acetamidic moiety containing 5-7-membered ?-lactam ring was prepared by a 4-step synthetic procedure. Five selected substances of this series were tested in vitro for inhibition of porcine kidney aminopeptidase M. 2-{4-[2-(2-Oxoperhydroazepin-1-yl)acetamido]phenoxy}acetic acid exhibited the highest activity with Ki = 243.6 ?M.
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18

IENAŞCU, Ioana M. C., Mariana N. ŞTEFĂNUŢ, Mihai-Cosmin PASCARIU, Iuliana M. POPESCU, Adina CĂTA, and Raluca POP. "Complexation of [2-(2-bromophenylcarbamoyl)phenoxy]acetic acid ethyl ester with β-cyclodextrin." Revue Roumaine de Chimie 64, no. 10 (2019): 849–57. http://dx.doi.org/10.33224/rrch/2019.64.10.03.

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19

Bakht, Mohammed Afroz, M. Shahar Yar, Anees A. Siddiqui, M. M. Abdullah, Hamadeh Tarazi, Moawiah M. Naffaa, and Ahmed M-Alafeefy. "Molecular properties prediction, synthesis, and diuretic activity of phenoxy acetic acid bearing pyrazolines." Medicinal Chemistry Research 22, no. 2 (May 22, 2012): 916–26. http://dx.doi.org/10.1007/s00044-012-0086-y.

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20

Khilya, V., O. Shablykina, M. Tsapko, S. Shilin, V. Moskvina, H. Bubela, and Yu Zabolotna. "Eu(fod)3 EFFECT ON 1H NMR SPECTRA OF 3-ARYLISOCOUMARINS AND 3-ARYL-3,4-DIHYDROISOCOUMARINS WITH ALKOXY, ESTER AND AMIDE GROUPS." Bulletin of Taras Shevchenko National University of Kyiv. Chemistry, no. 2(54) (2017): 74–80. http://dx.doi.org/10.17721/1728-2209.2017.2(54).15.

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The effect of the lanthanide shift reagent (LSR) – tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octa-dionate) of Europium – Eu(fod)3 – on 1H NMR spectra of functionalized 3-arylisocoumarins and 3-aryl-3,4-dihydroisocoumarins was investigated. Based on previous studies of LSR interactions with benzopyrones, it was expected that the main coordination centre for the Eu3+ would be the exocyclic Oxygen atom of the heterocycle, but the possibility of competition from aromatic substituent functional groups was also considered. By measuring lanthanide-induced shifts (LIS) of the proton signals of the molecules at different ratios of substrate and Eu(fod)3, specific LIS values were determined. Based on those, it was concluded that the main direction of LSR coordination with 3-(2-hydroxy-5-methylphenyl)-1Hisochromen-1-one, 3-(2-methoxy-5-methylphenyl)-1H-isochromen-1-one and 3-(2-methoxy-5-methylphenyl)isochroman-1-one is the exocyclic Oxygen atom of the heterocycle, because the maximum LIS were recorded for the H-8 atom of isochromone system of these derivatives. In the case of ethyl ester of [2-(4-(1-oxo-1H-isochromen-3-yl)phenoxy] acetic acid and methyl ester of [2-(4-(1-oxoisochroman-3-yl)phenoxy]acetic acid comparable LIS values were observed both for H-8 and for the methylene group of the hydroxyacetic acid fragment, therefore, in such molecules the coordination of the Eu3+ to the heterocycle or to the aliphatic ester group is almost equally probable. In spectrum of methyl ester of N-{[4-(1-oxo-1H-isochromen-3-yl)phenoxy]acetyl}valine and N-{[4-(1-oxoisochroman-3-yl)-phenoxy]acetyl}valine there are insignificant LIS of H-8; and the maximum LIS were observed for the signals of the protons neighboring the two carbonyl groups of hydroxyacetic acid and valine fragments. Thus, these compounds interact w
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21

Fujita, Takafumi, Madoka Sawazaki, Hitoki Matsuda, Yoshihiro Kojima, Yoshiyuki Asakura, and Kazuto Kobayashi. "Extraction and Decomposition of (4-chloro-2-methyl phenoxy) Acetic Acid Absorbed on Kaolin by Ultrasonic Irradiation." KAGAKU KOGAKU RONBUNSHU 32, no. 5 (2006): 454–60. http://dx.doi.org/10.1252/kakoronbunshu.32.454.

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22

Othman, Mudhar. "Synthesis and Study of Some fused Substituted 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro- phenoxy acetic acid and 2,4-dichlorophenoxy acetic acid." JOURNAL OF EDUCATION AND SCIENCE 29, no. 3 (September 1, 2020): 218–26. http://dx.doi.org/10.33899/edusj.2020.166251.

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23

Fujita, Takafumi, Erwin P. Ona, Yoshihiro Kojima, Hitoki Matsuda, Shinobu Koda, Naoki Tanahashi, and Yoshiyuki Asakura. "Ultrasonic Decomposition of (4-Chloro-2-methyl phenoxy)acetic Acid (MCPA) in Aqueous Solution." JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 36, no. 7 (2003): 806–11. http://dx.doi.org/10.1252/jcej.36.806.

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24

Shahar Yar, M., M. Afroz Bakht, A. A. Siddiqui, M. M. Abdullah, and Erik De Clercq. "Synthesis and evaluation of in vitro antiviral activity of novel phenoxy acetic acid derivatives." Journal of Enzyme Inhibition and Medicinal Chemistry 24, no. 3 (June 1, 2009): 876–82. http://dx.doi.org/10.1080/14756360802447917.

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25

Shaharyar, Mohammad, Anees Ahmad Siddiqui, and Mohamed Ashraf Ali. "Erratum to “Synthesis and evaluation of phenoxy acetic acid derivatives as anti-mycobacterial agents”." Bioorganic & Medicinal Chemistry Letters 17, no. 15 (August 2007): 4392–93. http://dx.doi.org/10.1016/j.bmcl.2007.03.088.

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26

Ma, Yangyang, Zhongtian Du, Junxia Liu, Fei Xia, and Jie Xu. "Selective oxidative C–C bond cleavage of a lignin model compound in the presence of acetic acid with a vanadium catalyst." Green Chemistry 17, no. 11 (2015): 4968–73. http://dx.doi.org/10.1039/c5gc00645g.

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27

Fry, Jack D., and Ward S. Upham. "Buffalograss Seedling Tolerance to Postemergence Herbicides." HortScience 29, no. 10 (October 1994): 1156–57. http://dx.doi.org/10.21273/hortsci.29.10.1156.

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In 1992 and 1993, 12 postemergence herbicide treatments were applied to field-grown buffalograss [Buchloe dactyloides (Nutt.) Engelm.] seedlings having 1 to 3 leaves and 2 to 4 tillers, respectively. The only herbicide treatments that did not cause plant injury at 1 or 2 weeks after treatment (WAT) or reduce turf coverage 4 or 6 WAT compared to nontreated plots (in 1992 or 1993) were (in kg·ha–1) 0.6 dithiopyr, 0.8 quinclorac, 2.2 MSMA, and 0.8 clorpyralid. Evaluated only in 1993, metsulfuron methyl (0.04 kg·ha–1) also caused no plant injury or reduction in coverage. Fenoxaprop-ethyl (0.2 kg·ha–1) caused severe plant injury and reduced coverage by >95% at 6 WAT. Dicamba reduced coverage by 11% at 6 WAT in 1992 but not 1993. The chemicals (in kg·ha–1) triclopyr (0.6), 2,4-D (0.8), triclopyr (1.1) + 2,4-D (2.8), 2,4-D (3.1) + triclopyr (0.3) + clorpyralid (0.2), and 2,4-D (2.0) + mecoprop (1.1) + dicamba (0.2) caused plant injury at 1 or 2 WAT in 1992 or 1993, but coverage was similar to that of nontreated turf by 6 WAT. Chemical names used: 3,6-dichloro-2-pyridinecarboxylic acid (clorpyralid); 3,6-dichloro-o-anisic acid (dicamba); (+/–)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid (diclofop); 3,5-pyridinedicarbothioic acid, 2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-S,S-dimethyl ester (dithiopyr); 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy] propanoate (fenoxaprop-ethyl); 2-(2,4-dichlorophenoxy)propionic acid (mecoprop); methyl 2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-amino]carbonyl]amino]sulfonyl]benzoate (metsulfuron methyl); monosodium salt of methylarsonic acid (MSMA); 3,7-dichloro-8-quinolinecarboxylic acid (quinclorac); [(3,5,6-trichloro-2-pyridinyl)oxy] acetic acid (triclopyr); (2,4-dichlorophenoxy) acetic acid (2,4-D).
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Havaldar, Freddy H., and Abhay R. Patil. "Syntheses of 1, 2, 4 Triazole Derivatives and their Biological Activity." E-Journal of Chemistry 5, no. 2 (2008): 347–54. http://dx.doi.org/10.1155/2008/394737.

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Cyclisation of [4-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-phenoxy]-acetic acid-N'-(substituted phenyl)-thiosemicarbazides with sodium metal in 99.0 % ethanol gave 3-[4-(4-substituted phenyl-5-thioxo-4,5-dihydro-1H-1,2,4 triazol-3-ylmethoxy)- phenyl]-2-phenyl-3H-quinazolin-4-one . The structures of the newly synthesized compounds have confirmed by IR,1H NMR and Mass spectra. The compounds have also been screened for their biological activity.
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29

Arul Dhas, D., I. Hubert Joe, S. D. D. Roy, and S. Balachandran. "DFT computation and experimental analysis of vibrational and electronic spectra of phenoxy acetic acid herbicides." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 108 (May 2013): 89–99. http://dx.doi.org/10.1016/j.saa.2013.01.081.

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30

Al-Mubaddel, Fahad S. "Removal of 2,4-Dichloro phenoxy acetic acid pesticide by solvent sublation: Experimental and theoretical studies." Arabian Journal of Chemistry 3, no. 2 (April 2010): 95–101. http://dx.doi.org/10.1016/j.arabjc.2010.02.005.

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31

Pramanik, Avijit, Srinivas Abbina, and Gopal Das. "Molecular, supramolecular structure and catalytic activity of transition metal complexes of phenoxy acetic acid derivatives." Polyhedron 26, no. 18 (November 2007): 5225–34. http://dx.doi.org/10.1016/j.poly.2007.07.033.

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32

Raskil’dina, Gul’nara Z., Evgeniya A. Yakovenko, Luisa M. M. Mryasova, and Simon S. Zlotskii. "SYNTHESIS AND HERBICID ACTIVITY OF ARYLOXYACETIC ACIDS AND AMIDES OF ARYLOXY ACETIC ACIDS CONTAINING CYCLOACETAL FRAGMENT." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 62, no. 1 (December 30, 2018): 91–97. http://dx.doi.org/10.6060/ivkkt.20196201.5753.

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The herbicidal activity of esters and amides based on commercially available phenoxy chlorides and 2,4-dichlorophenoxyacetic acids was studied. Esters of 2,2-methyl-4-hydroxymethyl-1,3-dioxolane, 5-ethyl-5-hydroxymethyl-1,3-dioxane and 1,3-dioxolan-4-ylmethanol and 1,3-dioxane-5 -ol (glycerin formulas), as well as amides containing gem-dichlorocyclopropane and 1,3-dioxolane fragments were obtained. The acid chlorides, 1,3-dioxacycloalkanes and secondary amines were prepared according to standard basic methods. Esters and amides were synthesized from these starting compounds in a short time and with a quantitative yield (more than 90%). As a result of the synthesis of a mixture of 1,3-dioxolan-4-ylmethyl phenylacetate and 1,3-dioxan-5-yl phenylacetate, the content of the 5-ring cyclic derivative over the 6-chain structure was predominant, which is obviously associated with greater activity in the esterification reaction of primary alcohol than secondary. The screening results showed that the activity relative to wheat of the 1,3-dioxalane ester of 2,4-dichlorophenoxyacetic acid is superior to the Octagon-Extra standard. With respect to peas, derivatives of 2,4-dichlorophenoxyacetic acid and 2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane are close to the standard for inhibition of shoot mass. The results of N-benzyl-N-[(2,2-dichlorocyclopropyl) methyl] -2-phenoxyacetamide and N-[(2,2-dichlorocyclopropyl) methyl]-N-(1,3-dioxolan-4-ylmethyl)-2-phenoxyacetamide with respect to peas and wheat also showed a marked herbicidal effect, close in value to the reference one. The test results of synthesized benzamides on wheat showed that, at a concentration of 100 mg/l, the compounds act approximately the same as the reference preparation at a dose of 50 mg/l. The obtained results prove the prospects of creating herbicidal preparations based on phenoxy- chlorides and 2,4-dichlorophenoxyacetic acids containing 1,3-dioxacycloalkane fragments. Therefore, these objects are very attractive for further study and synthesis of biologically active compounds containing the above pharmacophore groups.
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33

Malini, N., C. R. Ananadakumar, and S. Hari Ramakrishnan. "Regeneration of Indian maize genotypes (Zea mays L.) from immature embryo culture through callus induction." Journal of Applied and Natural Science 7, no. 1 (June 1, 2015): 131–37. http://dx.doi.org/10.31018/jans.v7i1.576.

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Callus induction and regeneration ability of five maize genotypes UMI 757, UMI 615, UMI 112, UMI 285 and CO 1 and one promising maize hybrids COH(M) 5 were investigated using 14 days old immature embryos as explants. Callus induction depends on genotype, explants (age and size of explants), medium, type of auxin and their concentration. Explants grown on Murashige and Skoog (MS) medium supplemented with 1.5 mg/l 2, 4 - D (2,4 – dichloro phenoxy acetic acid), 0.3 mg/l kinetin with 30 g/l maltose showed the highest percentage of embryogenic callus induction. Among the six genotypes tested, COH(M) 5 maize hybrids have highest percentage of embryogenic calli. The embryogenic calli incubated on MS medium supplemented with 1.5 mg/l BAP (Benzyl Amino Purine), 0.2 mg/lNAA (Naphthalene Acetic Acid) with 1.0 mg/l kinetin was found to give the highest organogenesis response and regeneration of plantlets.
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34

Al-Zaben, M. I., and W. K. Mekhamer. "Removal of 4-chloro-2-methyl phenoxy acetic acid pesticide using coffee wastes from aqueous solution." Arabian Journal of Chemistry 10 (May 2017): S1523—S1529. http://dx.doi.org/10.1016/j.arabjc.2013.05.003.

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35

Galanin, N. E., L. A. Yakubov, and G. P. Shaposhnikov. "Synthesis and spectral properties of [3-(heptyloxy)phenoxy]acetic acid and its derived meso-sibstituted tetrabenzoporphyrins." Russian Journal of General Chemistry 78, no. 9 (September 2008): 1802–7. http://dx.doi.org/10.1134/s1070363208090259.

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36

Mokale, Santosh N., Manjusha C. Nevase, Nikhil S. Sakle, Pritam N. Dube, Vishakha R. Shelke, Swati A. Bhavale, and Afreen Begum. "Synthesis and in-vivo hypolipidemic activity of some novel substituted phenyl isoxazol phenoxy acetic acid derivatives." Bioorganic & Medicinal Chemistry Letters 24, no. 9 (May 2014): 2155–58. http://dx.doi.org/10.1016/j.bmcl.2014.03.030.

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37

Byriel, KA, DE Lynch, G. Smith, and CHL Kennard. "Molecular Cocrystals of Carboxylic-Acids. V. The Crystal-Structures of (2-Carboxy-phenoxy)acetic Acid and Its 1 : 1 Adduct With 4-Aminobenzoic Acid." Australian Journal of Chemistry 44, no. 10 (1991): 1459. http://dx.doi.org/10.1071/ch9911459.

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The crystal structures of (2-carboxyphenoxy)acetic acid (cpaa) (1) and its 1 : 1 adduct [( cpaa )(4-aba)] (2) with 4-aminobenzoic acid have been determined by X-ray diffraction and refined to residuals R 0.077, (1), and 0.051, (2), for 783 and 1062 observed reflections, respectively. The dicarboxylic acid (1) is extended into a one-dimensional zig-zag polymer by hydrogen bonding through the two acid groups [O…O, 2.67(1)Ǻ]. The adduct (2) represents the first example of a phenoxyalkanoic involved in a hetero-dimer association through the conventional cyclic hydrogen-bonding system [O…O, 2.54, 2.68(1)Ǻ]. The 2-carboxy group is also weakly hydrogen bonded to the 4-amino group of (4-aba) [O…N, 2.99(1)Ǻ], and in both (1) and (2) it has an intramolecular hydrogen bond to the ether oxygen of the oxyacetic acid side chain.
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38

Pawar, M. J., and B. K. Karale. "Synthesis of Some New 3-Substituted Benzofuran Derivatives by Cyclization of Various Phenoxy Acetic Acid Ethyl Esters." Synthetic Communications 40, no. 24 (November 16, 2010): 3603–8. http://dx.doi.org/10.1080/00397910903457308.

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39

Mahendra, Madegowda, Beeranahally H. Doreswamy, Mandayam A. Sridhar, Javaregowda S. Prasad, Shaukath A. Khanum, Sheena Shashikanth, and Belagur S. Sudha. "Synthesis and X-Ray Crystal Structure Study of ]2-Methyl-4-(2-methylbenzoyl)-phenoxy] Acetic Acid Hydrazide." Structural Chemistry 15, no. 3 (June 2004): 211–14. http://dx.doi.org/10.1023/b:stuc.0000021529.80244.c4.

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40

Mokale, Santosh N., Priyanka T. Sanap, and Devanand B. Shinde. "Synthesis and hypolipidemic activity of novel 2-(4-(2-substituted aminothiazole-4-yl) phenoxy) acetic acid derivatives." European Journal of Medicinal Chemistry 45, no. 7 (July 2010): 3096–100. http://dx.doi.org/10.1016/j.ejmech.2010.03.043.

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41

Oreilly, EJ, G. Smith, CHL Kennard, and TCW Mak. "Metal Phenoxyalkanoic Acid Interactions. XXV. The Crystal Structures of (2-Formyl-6-Methoxyphenoxy)Acetic Acid and Its Zinc(II) Complex and the Lithium, Zinc(II) and Cadmium(II) Complexes of (2-Chlorophenoxy)Acetic Acid." Australian Journal of Chemistry 40, no. 7 (1987): 1147. http://dx.doi.org/10.1071/ch9871147.

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The crystal structures of (2-formyl-6-methoxyphenoxy)acetic acid (1), diaquabis [(2-formyl-6-methoxyphenoxy) acetato ]zinc(11) (2), tetraaquabis [(2-chlorophenoxy) acetato ]zinc(11) (3), triaquabis [(2-chlorophenoxy) acetato ]cadmium(11) dihydrate (4) and lithium (2-chloro- phenoxy )acetate 1.5 hydrate (5) have been determined by X-ray diffraction. The acid (1) forms centrosymmetric hydrogen-bonded cyclic dimers [O…0, 2.677(6) �] which are non-planar. Complex (2) is six-coordinate with two waters [Zn- Ow , 1.997(2) �] and four oxygens from two asymmetric bidentate carboxyl groups [Zn-O, 2.073, 2.381(2) �] completing a skew trapezoidal bipyramidal stereochemistry. Complex (5) is also six-coordinate but is octahedral, with two trans-related unidentate carboxyl oxygens [mean Zn-O, 2.134(9) �] and four waters [mean Zn-O, 2.081(9) �]. The seven-coordinate complex (4) has crystallographic twofold rotational symmetry relating two :symmetric bidentate acid ligands [ Cd -O, 2.26, 2 48(:) �] and two waters [ Cd -O, 2.34(2) �] while the third water lies on this axis [ Cd -O, 2.27(2) �]. In contrast to the monomers (2)-(4), complex (5) is polymeric with tetrahedral lithium coordinated to one water and three carboxylate oxygens [mean Li-0, 1.95(1) �]. The essential conformation of the free acid is retained in complexes (2), (3) and (4) but in (5), it is considerably changed.
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42

Smith, Graham, and Daniel E. Lynch. "Crystal structures and hydrogen bonding in the anhydrous tryptaminium salts of the isomeric (2,4-dichlorophenoxy)acetic and (3,5-dichlorophenoxy)acetic acids." Acta Crystallographica Section E Crystallographic Communications 71, no. 6 (May 23, 2015): 671–74. http://dx.doi.org/10.1107/s205698901500907x.

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The anhydrous salts of 2-(1H-indol-3-yl)ethanamine (tryptamine) with isomeric (2,4-dichlorophenoxy)acetic acid (2,4-D) and (3,5-dichlorophenoxy)acetic (3,5-D), both C10H13N2+·C8H5Cl2O3−[(I) and (II), respectively], have been determined and their one-dimensional hydrogen-bonded polymeric structures are described. In the crystal of (I), the aminium H atoms are involved in three separate inter-species N—H...O hydrogen-bonding interactions, two with carboxylate O-atom acceptors and the third in an asymmetric three-centre bidentate carboxylateO,O′chelate [graph setR12(4)]. The indole H atom forms an N—H...Ocarboxylatehydrogen bond, extending the chain structure along theb-axis direction. In (II), two of the three aminium H atoms are also involved in N—H...Ocarboxylatehydrogen bonds similar to (I) but with the third, a three-centre asymmetric interaction with carboxylate and phenoxy O atoms is found [graph setR12(5)]. The chain polymeric extension is also alongb. There are no π–π ring interactions in either of the structures. The aminium side-chain conformations differ significantly between the two structures, reflecting the conformational ambivalence of the tryptaminium cation, as found also in the benzoate salts.
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43

Spadavecchia, Jolanda, Giuseppe Ciccarella, Alessandro Buccolieri, Giuseppe Vasapollo, and Roberto Rella. "Synthesis of tailored phthalocyanines and their application as spin coated films in volatile organic compound detection." Journal of Porphyrins and Phthalocyanines 07, no. 08 (August 2003): 572–78. http://dx.doi.org/10.1142/s1088424603000720.

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29H,31H-(2,4-di-t-amylphenoxy)phthalocyanine, Zn (II) tetra-4-(2,4-di-t-amylphenoxy) phthalocyanine and Zn (II) tris-(2,4-di-t-amylphenoxy)-[4-(4-mercapto-phenyliminomethyl)- phenoxy]phthalocyanine were synthesized and their molecular structures were confirmed by LC-MS, 1 H NMR, FT-IR and UV-vis spectra. Spin coated layers of these phthalocyanines have been used as optochemically interactive materials for volatile organic compounds detection in the UV-vis spectral range. The results show a good sensitivity and selectivity depending on both the metal and the peripheral substituents. Optical sensitivity towards tert-butylamine, diethylamine, dibutylamine, 2-butanone and acetic acid has been monitored.
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44

Sushma B K and Raveesha H R. "FTIR, GC-MS and HPLC analysis of Baliospermum montanum (Willd.) Muell. Arg." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (September 22, 2020): 5059–66. http://dx.doi.org/10.26452/ijrps.v11i4.3101.

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The present work is aimed to determine the chemical constituents in Baliospermum montanum methanolic extracts. An in vitro regenerated procedure was developed for the induction of callus from stem explant cultured on Murashige and Skoog (MS) medium fortified with various concentration and permutations of 2, 4-dichloro phenoxy acetic acid, 1-naphthalene acetic acid, 6-benzyl amino purine and gibberellic acid. FTIR & GC-MS analysis was done according to standard procedure. The quantitative estimation of β-sitosterol was done by HPLC method. Maximum fresh and dry weight of callus was estimated in the combination of GA3 (0.5 mg/L) + NAA (2 mg/L) compared to other concentration. The FTIR analysis showed various functional compounds with different characteristic peak values in the extracts. Major bioactive constituents were recognized in the GC-MS analysis. Root extract revealed the existence of 1-hexadecanol, pentanoic acid, 2-(aminooxy)- and 1-hexacosanol. Leaf extract showed the presence of propanoic acid, 2-oxo-, trimethylsilyl ester, 9,12-octadecadienoic acid (z,z)-, trimethylsilyl ester, docosane, 1,22-dibromo- and pentatriacontane. Stem and stem derived callus exhibit the presence of 1,6,3,4-dihydro-2-deoxy-beta-d-lyxo-hexopyranose, n-hexadecanoic acid and pentanoic acid, 2-(aminooxy). The methanolic extract of leaf exhibited 0.2149 % of β-sitosterol content. There were no peaks observed in the root, stem and stem derived callus. Further studies are necessary for the isolation and characterization of bioactive compounds from B. montanum.
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45

Dernoeden, P. H., and M. A. Fidanza. "Fenoxaprop Activity Influenced by Auxin-like Herbicide Application Timing." HortScience 29, no. 12 (December 1994): 1518–19. http://dx.doi.org/10.21273/hortsci.29.12.1518.

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Fenoxaprop is used on turfgrasses to control smooth crabgrass [Digitaria ischaemum (Schreb. ex Sweib.) Schreb. ex Muhl.] and other annual grass weeds. Our objective was to determine if a broadleaf weed herbicide (BWH = 2,4-D + mecoprop + dicamba) would affect fenoxaprop activity. The BWH was applied several days or weeks before and after fenoxaprop was applied. Smooth crabgrass control by fenoxaprop was reduced significantly when the BWH was applied ≤14 days before fenoxaprop was applied. Extremely poor crabgrass control occurred when fenoxaprop was tank-mixed with the BWH. There was no reduction in crabgrass control when the BWH was applied 21 days before or ≥3 days after fenoxaprop. Chemical names used: ethyl ester of (±)-2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoic acid (fenoxaprop); 2,4-dichlorophenoxy acetic acid (2,4-D); (+)-2-(4-chloro-2-methylphenoxy)propanoic acid (mecoprop); 3,6-dichloro-2-methoxybenzoic acid (dicamba).
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46

You, Zhong-Lu, Hai-Liang Zhu, Wei-Sheng Liu, and Min-Yu Tan. "{2-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)methyl]phenoxy}acetic acid nitrate." Acta Crystallographica Section E Structure Reports Online 59, no. 12 (November 8, 2003): o1920—o1922. http://dx.doi.org/10.1107/s1600536803025339.

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47

Wang, Yanliang, Haiyue Zhou, Yabing Wang, Fujian Li, and Xiaoqi Sun. "Separation of high-purity yttrium from ion-absorbed rare earth concentrate using (2,6-dimethylheptyl) phenoxy acetic/propanoic acid." Separation and Purification Technology 184 (August 2017): 280–87. http://dx.doi.org/10.1016/j.seppur.2017.04.049.

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48

Rani, N. Latha, T. Prashanth, M. A. Sridhar, V. Lakshmi Ranganatha, and A. K. Shaukath. "Hirshfeld Surface Analysis and Crystal Structure of [2-Bromo-4-(4-Fluoro-Benzoyl)-Phenoxy]-Acetic Acid Ethyl Ester." Molecular Crystals and Liquid Crystals 629, no. 1 (April 12, 2016): 78–85. http://dx.doi.org/10.1080/15421406.2015.1106908.

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49

Ajees, A. Abdul, Shubhalaxmi, B. S. Manjunatha, S. Madan Kumar, K. Byrappa, and K. Subrahmanya Bhat. "Structural analysis of chalcone derivative: 2‐{4‐[(2E)‐3‐(4‐fluorophenyl)prop‐2‐enoyl]phenoxy}acetic acid hydrate." Chemical Data Collections 9-10 (August 2017): 61–67. http://dx.doi.org/10.1016/j.cdc.2017.03.004.

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50

Fleeker, James. "Two Enzyme Immunoassays to Screen for 2,4-Dichlorophenoxyacetic Acid in Water." Journal of AOAC INTERNATIONAL 70, no. 5 (September 1, 1987): 874–78. http://dx.doi.org/10.1093/jaoac/70.5.874.

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Abstract Two solid-phase enzyme immunoassays were developed to measure 2,4-dichlorophenoxyacetic acid (2,4-D), using 2 sets of structurally distinct immunogens and enzyme ligands. The 2,4-D analog, 2-methyl- 4-chlorophenoxyacetic acid (MCPA), gave a similar response with both methods, whereas other phenoxy herbicides cross-reacted differently. In method A, the aromatic moiety of 2,4-D was distal from the carrier protein and labeled enzyme, whereas in method B, the acetic acid portion of the herbicide was distal. The use of both methods to screen for this herbicide in ground water and municipal and river water reduced the number of false-positive responses. Water sources having a low background response could be monitored with either method alone. When a concentration step, with disposable C18 extraction columns, was used, the limit of sensitivity was 5 ng/L,. Method A was the more sensitive of the 2 methods with a limit of detection of 10 j*g/L without the concentration step
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