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Journal articles on the topic 'Phenyl succinimide'

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1

Ravindra, Dhivare, Chaudhari Prashant, and Rajput Shankarsing. "Synthesis of Pyridine and Phenyl Succinimides by Green Pathway and Their Antimicrobial Assay." American Journal of Heterocyclic Chemistry 4, no. 1 (2018): 26–29. https://doi.org/10.11648/j.ajhc.20180401.13.

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<strong>Abstract </strong> A simple and clean green method was implemented for the preparation of different <strong><em>succinimide derivatives</em></strong> by means of the N-substituted anilines or N-substituted 2-aminopyridines with succinic anhydride with the heating in an aqueous medium. The total synthesized 3a-j compounds were evaluated against antibacterial and antifungal species.
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2

Boudriga, Sarra, Saoussen Haddad, Vikneswaran Murugaiyah, et al. "Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity." Molecules 25, no. 8 (2020): 1963. http://dx.doi.org/10.3390/molecules25081963.

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A novel one-pot [3+2]-cycloaddition reaction of (E)-3-arylidene-1-phenyl-succinimides, cyclic 1,2-diketones (isatin, 5-chloro-isatin and acenaphtenequinone), and diverse α-aminoacids such as 2-phenylglycine or sarcosine is reported. The reaction provides succinimide-substituted dispiropyrrolidine derivatives with high regio- and diastereoselectivities under mild reaction conditions. The stereochemistry of these N-heterocycles has been confirmed by four X-ray diffraction studies. Several synthetized compounds show higher inhibition on acetylcholinesterase (AChE) than butyrylcholinesterase (BChE
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3

Dobre, Adela F., Augustin M. Madalan, and Petre Ionita. "The Crystal Structures of Some Bromo-Derivatives of the DPPH Stable Free Radical." Molbank 2024, no. 3 (2024): M1880. http://dx.doi.org/10.3390/m1880.

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Bromination of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical with bromine or N-bromo-succinimide (NBS) affords a complex mixture of bromo- and nitro-derivatives of the starting material. In this study, by chromatographic separation, most of the reaction products were isolated. Suitable crystals for X-ray measurements were obtained and characterized for the compounds 2-p-bromophenyl-2-phenyl-1-picrylhydrazyl free radical (Br-DPPH), 2-p-bromophenyl-2-phenyl-1-picrylhydrazine (Br-DPPH-H), and 2,2-(p-bromophenyl)-1-(2-bromo-4,6-dinitrophenyl)hydrazine (Br2-DPPBr-H).
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4

Ravindra, S. Dhivare, and S. Rajput Shankarsing. "Synthesis, physicochemical probe and antimicrobial assay of bis-chalcone, pyrazole, amino-pyrimidine and malononitrile derivatives from five and six membered cyclic imides." Iranian Journal of Organic Chemistry 8, no. 4 (2017): 1909–18. https://doi.org/10.5281/zenodo.3911281.

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<strong>Abstract </strong> Heterocyclic imides greatly involved in the development of organic synthesis. Coloured flavonoids like bis-chalcones are formed by microwave-assisted solvent-free route using phenyl succinimide, glutarimide, and vanillin. To achieve the <em><strong>pyrazole</strong></em> and <strong><em>amino-pyrimidine</em></strong> derivatives by the cyclization of bis-chalcone with hydrazine hydrate and guanidine nitrate via microwave method. Then <strong><em>dimalononitriles</em></strong> were produced by the active methylene group of dinitrile with cyclic imides. Hence the physi
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5

Li, Shao-Hua, and et al. "Crystal structure of 3,4-bis-(acetyloxy)-N-phenyl-succinimide, C14H13NO6." Zeitschrift für Kristallographie - New Crystal Structures 227, no. 3 (2012): 375–76. http://dx.doi.org/10.1524/ncrs.2012.0190.

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6

R.S., Dhivare, S. Rajput S., and Yadav R. "Synthesis of new series of N-substituted phenyl succinimide and glutarimide derivatives for the study of their antifungal activity." International Journal of Chemical Studies 4, no. 1 (2015): 61–63. https://doi.org/10.5281/zenodo.3911256.

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<strong>Abstract</strong> A new series of <strong><em>N-substituted phenyl cyclic imides</em></strong> were synthesized via the reaction between succinic, glutaric anhydride, and primary aromatic amines in presence of benzene and acetyl chloride. The synthesized derivatives were characterized by IR, <sup>1</sup>HNMR, and <sup>13</sup>CNMR spectroscopy, and antifungal activity behavior was studied using the disc diffusion method.
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7

V., Mishra. "Coordination polymers of copper( II) imides with polymeric heterocyclic Schiff bases of thiazole derivatives." Journal of India Chemical Society Vol. 79, Apr 2002 (2002): 374–75. https://doi.org/10.5281/zenodo.5849358.

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Department of Post- Graduate Studies in Chemistry, Nehru College, Chhibramau-209 721, India <em>Manuscript received 29 September 2000. revised 26 July 2001. accepted 1 September 2001</em> Two polymeric ligands, L<sub>1</sub> and L<sub>2</sub> were synthesized by polymerizing new heterocyclic Schiff bases 2-hydroxy-1-benzylidene-2-amino&middot; 4-phenylthiazole and 2-hydroxy-1-benzylidene-2-amino-4-phenyl-5-phenylazothiazole, with 1,6-dichlorohexane. L<sub>1</sub>. L<sub>2</sub> gave solid chelates with copper( II) phthalimide or succinimide. The metal ion is coordinated through nitrogen of imi
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8

Mutlaq, Dakhil Z., Ali A. A. Al-Shawi, and Rafid H. Al-Asadi. "Synthesis, characterization, anticancer activity, and molecular docking of novel maleimide–succinimide derivatives." Egyptian Pharmaceutical Journal 20, no. 4 (2021): 303–12. http://dx.doi.org/10.4103/epj.epj_26_21.

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Background and objective A wide range of maleimide heterobifunctional reagents are used for the preparation of targeted therapeutics. Succinimide derivatives are important compounds found in a variety of natural products that exhibit remarkable biological and pharmaceutical activity. The creation of new maleimide–succinimide derivatives will increase the importance and medicinal applications of these groups. Materials and methods The reaction of bismaleimide (1–2) with phenylhydrazide and 4-methylbenzohydrazide resulted in the formation of N’-[1-(4-[2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl] phenyl
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9

Mahi, Ahmed, M. Belbachir, Abdelkader Ammari, R. Meghaber, and M. I. Ferrahi. "Synthesis and characterization of poly(N-phenyl succinimide-thiophene) conducting polymer catalyzed by Maghnite-H+." Journal of Electroanalytical Chemistry 823 (August 2018): 92–97. http://dx.doi.org/10.1016/j.jelechem.2018.05.039.

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10

Hambley, TW, IA Newsom, and S. Sternhell. "The Structure of (1'RS, 2SR,3RS,4'SR)-2,3-(Cyclohex-2′-en-1′, 4′-ylene)-N-(4″-methyl-phenyl)succinimide." Australian Journal of Chemistry 38, no. 3 (1985): 513. http://dx.doi.org/10.1071/ch9850513.

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A single-crystal X-ray structure determination gave the crystal and molecular parameters of\ (1′RS,2SR,3RS,4′SR)-2,3-(cyclohex-2′-en-1′,4′- ylene )-N-(4′-methylphenyl) succinimide , including the positions of all hydrogen atoms and the conformation of the 4′-methylphenyi group. The latter is possibly controlled by steric interactions between the ortho hydrogen atoms on the 4″-methylphenyl ring and the carbonyl oxygen atoms of the imide moiety. The six atoms of the imide moiety [O(10), C(9), N(8), C(13), O(14) and C(5) on the ORTEP plot in Fig. 1] are planar within 0.04 Ǻ.
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11

Frister, Hermann, and Eckhard Schlimme. "Ringöffnungsreaktionen an bioreaktiven Lactamsystemen / Ring Opening Reactions of Bioreactive Lactam Systems." Zeitschrift für Naturforschung C 42, no. 5 (1987): 603–12. http://dx.doi.org/10.1515/znc-1987-0518.

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Abstract 1-β-ᴅ-Ribofuranosylpyrrolidin-2,5-dione (9) was synthesized by ribosylation of N-silylated succinimide (7) with 1,2,3,5-tetra-O-acetyl-β-ᴅ-ribofuranose in acetonitril in the presence of tin tetrachloride. The compounds 9, 1-β-ᴅ-ribofuranosyl-l-H-pyrrol-2,5-dione (5) and N-methyl- maleinimide (2) were converted with ammonia to the ring-opened components 16. 14 and 15. The bioreactivity of the N-maleinimide derivatives 2 and 5 with respect to addition and ring-opening reactions with amino acid side chains containing either thiol or amino groups was shown in model reactions with glutathi
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12

Vitnik, Vesna D., Željko J. Vitnik, Nebojša R. Banjac, Nataša V. Valentić, Gordana S. Ušćumlić, and Ivan O. Juranić. "Quantum mechanical and spectroscopic (FT-IR, 13C, 1H NMR and UV) investigations of potent antiepileptic drug 1-(4-chloro-phenyl)-3-phenyl-succinimide." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 117 (January 2014): 42–53. http://dx.doi.org/10.1016/j.saa.2013.07.099.

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13

Journal, Baghdad Science. "Reaction of Thiols with formaldehyde in Presnce of succinimid and Reduction of Phenyl Tetrazole Derivative with Hydrogen and Borohydraide." Baghdad Science Journal 8, no. 2 (2011): 388–93. http://dx.doi.org/10.21123/bsj.8.2.388-393.

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One of most the important compounds which have active hydrogen (substrate) is the thiols which used in a wide field in preparation of Mannich bases . A large number of Mannich bases have been prepared as a biologically active compound (pharmaceutical, pesticides, bactericidal, fungicidal and tuberculostatic) and in order to correlate their structure and reactivity with their pharmacological activity such as . It has been reported that the reaction is easily proceeded by using primary and secondary amine beside formaldehyde. But when we tried the reaction of thiols as substrate and formaldehyde
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14

Hachiam, Abdul faris Hussian. "Reaction of Thiols with formaldehyde in Presnce of succinimid and Reduction of Phenyl Tetrazole Derivative with Hydrogen and Borohydraide." Baghdad Science Journal 8, no. 2 (2011): 388–93. http://dx.doi.org/10.21123/bsj.2011.8.2.388-393.

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One of most the important compounds which have active hydrogen (substrate) is the thiols which used in a wide field in preparation of Mannich bases . A large number of Mannich bases have been prepared as a biologically active compound (pharmaceutical, pesticides, bactericidal, fungicidal and tuberculostatic) and in order to correlate their structure and reactivity with their pharmacological activity such as . It has been reported that the reaction is easily proceeded by using primary and secondary amine beside formaldehyde. But when we tried the reaction of thiols as substrate and formaldehyde
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15

Rajeswari S, Harindran Suhana, and Kalaivizhi R. "Studies on the Spectral, Anti-Bacterial and Anti-Fungal Activities of 1-((Dicyclohexylamino) (Phenyl) Methyl) Pyrrolidine-2, 5-Dione and Few of its Metal Complexes." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 3124–36. http://dx.doi.org/10.26452/ijrps.v11ispl4.4653.

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1-((dicyclohexylamino)(phenyl)methyl) pyrrolidine-2,5-dione (SDB) has been synthesized as a result of succinimide, benzaldehyde and dicyclohexylamine Mannich base condensation and its CoII, NiII and CuII complexes were prepared. The structure of the Mannich Base ligand (SDB) was elucidated on the basis of FT-IR, 1H NMR, 13C NMR and Mass spectral studies. The monomeric and non-electrolytic nature of the metal complexes is evidenced by their magnetic susceptibility and low conductance data studies. Spectral tests, mainly FT-IR studies as well as elemental analysis, were carried out to verify the
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16

Perisic-Janjic, Nada, Roman Kaliszan, Natasa Milosevic, Gordana Uscumlic, and Nebojsa Banjac. "Chromatographic retention parameters in correlation analysis with in silico biological descriptors of a novel series of N-phenyl-3-methyl succinimide derivatives." Journal of Pharmaceutical and Biomedical Analysis 72 (January 2013): 65–73. http://dx.doi.org/10.1016/j.jpba.2012.09.006.

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17

Chung, J. M., J. R. Huguenard, and D. A. Prince. "Transient enhancement of low-threshold calcium current in thalamic relay neurons after corticectomy." Journal of Neurophysiology 70, no. 1 (1993): 20–27. http://dx.doi.org/10.1152/jn.1993.70.1.20.

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1. The alterations of voltage-sensitive calcium currents produced in thalamic cells by injury were investigated under voltage clamp using patch-clamp recordings in the whole-cell configuration. 2. One day after unilateral cortical ablation in immature rats (postnatal day 7), low-threshold transient calcium (T) currents in acutely isolated thalamic relay neurons (RNs) were increased by 68% compared with contralateral controls (P &lt; 0.001). Three days after the operation, T currents in injured neurons were at 44% of control levels (P &lt; 0.001). On the other hand, high-threshold (L) calcium c
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18

Ravindra, S. Dhivare, and S. Rajput Shankarsing. "Synthesis and antimicrobial evaluation of some novel bis-heterocyclic chalcones from cyclic imides under microwave irradiation." Chemical Science Review and Letters 4, no. 15 (2015): 937–44. https://doi.org/10.5281/zenodo.3909689.

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Abstract Synthesis of a new series of bis-heterocyclic chalcone derivatives has been reported. The condensation proceeded by the one-pot reaction of N-phenyl succinimides and 4-hydroxy-3-methoxy benzaldehyde in the presence of neutral alumina under microwave irradiation. The advantages of this method are high yield, shorter reaction time, and simple workup procedure. Most of the synthesized compounds have shown moderate to significant antimicrobial activity against different microbial strains. &nbsp;
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19

Bogza, S. L., K. I. Kobrakov, M. Yu Zubritskii, S. Yu Suikov, and V. I. Dulenko. "Acylation of n-phenyl-2-(indol-3-yl)succinimides." Chemistry of Heterocyclic Compounds 33, no. 1 (1997): 74–77. http://dx.doi.org/10.1007/bf02290750.

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20

Augustin, M., and P. Jeschke. "Synthese und Reaktionen von 2-Arylhydrazono-N-phenyl-succinimiden." Journal f�r Praktische Chemie 329, no. 4 (1987): 607–16. http://dx.doi.org/10.1002/prac.19873290411.

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21

Dinçer, Muharrem, Namık Özdemir, İbrahim Yılmaz, Alaaddin Çukurovalı, and Orhan Büyükgüngör. "1-Methyl-1-phenyl-3-[1-hydroxyimino-2-(succinimido)ethyl]cyclobutane." Acta Crystallographica Section C Crystal Structure Communications 60, no. 9 (2004): o674—o676. http://dx.doi.org/10.1107/s0108270104018074.

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22

BOGZA, S. L., K. I. KOBRAKOV, M. YU ZUBRITSKII, S. YU SUIKOV, and V. I. DULENKO. "ChemInform Abstract: Acylation of N-Phenyl-2-(indol-3-yl)succinimides." ChemInform 28, no. 26 (2010): no. http://dx.doi.org/10.1002/chin.199726149.

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23

Dhivare, Ravindra. "Synthesis of Pyridine and Phenyl Succinimides by Green Pathway and Their Antimicrobial Assay." American Journal of Heterocyclic Chemistry 4, no. 1 (2018): 26. http://dx.doi.org/10.11648/j.ajhc.20180401.13.

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24

Prashant, P. Chaudhari, S. Dhivare Ravindra, and S. Rajput Shankarsing. "Microwave Assisted Synthesis of Heterocycles Accompanied by Antimicrobial Screening." Journal of Advances and Scholarly Researches in Allied Education XV, no. 2 (2018): 324–29. https://doi.org/10.5281/zenodo.3911291.

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<strong>Abstract </strong> A clean, efficient, and solvent-free method for the synthesis of Bis-chalcones and Pyrazoles was carried out with the help of microwave irradiations and neutral alumina. The novel class of Bischalcones and pyrazoles were comprehended by the treatment of N-phenyl succinimides with p-fluoro benzaldehyde. The cyclic imide on condensation with p-fluoro benzaldehyde furnished a series of bis chalcones and further, they undergo cyclization with hydrazine hydrate to furnish pyrazoles. This condensation could make better and easier by a solvent-free mechanism with the help o
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25

Rankin, Gary O., David J. Yang, E. Patricia Lahoda, Kim Cressey-Veneziano, Marsha L. Bailey, and Patrick I. Brown. "Acute nephrotoxicity of N-phenyl and N-(monochlorophenyl) succinimides in Fischer 344 and Sprague-Dawley rats." Toxicology 34, no. 4 (1985): 299–308. http://dx.doi.org/10.1016/0300-483x(85)90140-4.

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26

Obniska, Jolanta, Alfred Zejc, and Janina Karolak-Wojciechowska. "Synthesis, physicochemical and anticonvulsant properties of new N-pyridyl derivatives of 3-phenyl- and 3,3-diphenyl-succinimides." Il Farmaco 54, no. 7 (1999): 423–29. http://dx.doi.org/10.1016/s0014-827x(99)00033-6.

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27

Bayat, Mohammad, Seyedeh Razieh Hosseini, and Elnaz Asmari. "Simple synthesis of (E) and (Z)-2-(arylmethylidene)-N-phenyl succinimides via Wittig olefination by using PS-TPP resin." Phosphorus, Sulfur, and Silicon and the Related Elements 192, no. 1 (2016): 98–102. http://dx.doi.org/10.1080/10426507.2016.1225739.

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28

Obniska, Jolanta, Alfred Zejc, and Janina Karolak-Wojciechowska. "ChemInform Abstract: Synthesis, Physicochemical and Anticonvulsant Properties of New N-Pyridyl Derivatives of 3-Phenyl- and 3,3-Diphenyl-succinimides." ChemInform 30, no. 44 (2010): no. http://dx.doi.org/10.1002/chin.199944101.

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29

Kamiński, Krzysztof, Jolanta Obniska, Iwona Chlebek, Piotr Liana, and Elżbieta Pękala. "Synthesis and biological properties of new N-Mannich bases derived from 3-methyl-3-phenyl- and 3,3-dimethyl-succinimides. Part V." European Journal of Medicinal Chemistry 66 (August 2013): 12–21. http://dx.doi.org/10.1016/j.ejmech.2013.05.011.

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30

Shweta, Sharma, Sharma Chirag, Thadhaney Bhawana, and L. Talesara G. "Synthesis of phthalimido or succinimido[2-aryl-4-oxo-3-{2-phenyl-4(3H)- quinazolinon-3-yl}-1,3-thiazolidin-5-yl]ethanoate." Journal of Indian Chemical Society Vol. 86, Apr 2009 (2009): 397–401. https://doi.org/10.5281/zenodo.5809998.

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Synthetic Organic Chemistry Laboratory, Department of Chemistry, M. L. Sukhadia University, Udaipur-313 001, Rajasthan, India <em>E-mail</em> : gtalesara@yahoo.com <em>Manuscript received 11 June 2008, revised 5 November 2008, accepted 23 December 2008</em> Treatment of benzoxazine 1&nbsp;with hydrazine hydrate in ethanol furnished 3-amino-2-phenylquinazolin-4-(3<em>H</em>)- one 2, which upon condensation with aldehydes 3a-d yielded the corresponding 3-arylideneamino derivatives 4a-d. Cyclization of these derivatives using mercaptosuccinic acid afforded 1 ,3-thiazolidin-4-one ethanoic acids 5a
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31

Kaminski, Krzysztof, Jolanta Obniska, Iwona Chlebek, Piotr Liana, and Elzbieta Pekala. "ChemInform Abstract: Synthesis and Biological Properties of New N-Mannich Bases Derived from 3-Methyl-3-phenyl- and 3,3-Dimethyl-succinimides. Part 5." ChemInform 44, no. 52 (2013): no. http://dx.doi.org/10.1002/chin.201352187.

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32

Pinchon, Erica, Mary Arugula, Kapil Pant, and Sameer Singhal. "Enhancement of Electrochemical Performance of Bilirubin Oxidase Modified Gas Diffusion Biocathode by Porphyrin Precursor." Advances in Physical Chemistry 2018 (June 3, 2018): 1–9. http://dx.doi.org/10.1155/2018/4712547.

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Recent studies have focused on tailoring the catalytic currents of multicopper oxidase (MCO) enzymes-based biocathodes to enhance oxygen reduction. Biocathodes modified with natural substrates specific for MCO enzymes demonstrated drastic improvement for oxygen reduction. Performance of 1-pyrenebutanoic acid, succinimidyl ester (PBSE), and 2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde (Di-Carb) oriented bilirubin oxidase (BOx) modified gas diffusion biocathode has been highly improved by incorporating hematin, a porphyrin precursor as electron transfer enhancement moiety. Hematin modified el
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33

Barrington, W. W., K. A. Jacobson, A. J. Hutchison, M. Williams, and G. L. Stiles. "Identification of the A2 adenosine receptor binding subunit by photoaffinity crosslinking." Proceedings of the National Academy of Sciences 86, no. 17 (1989): 6572–76. http://dx.doi.org/10.1073/pnas.86.17.6572.

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A high-affinity iodinated agonist radioligand for the A2 adenosine receptor has been synthesized to facilitate studies of the A2 adenosine receptor binding subunit. The radioligand 125I-labeled PAPA-APEC (125I-labeled 2-[4-(2-[2-[(4- aminophenyl)methylcarbonylamino]ethylaminocarbonyl]- ethyl)phenyl]ethylamino-5'-N-ethylcarboxamidoadenosine) was synthesized and found to bind to the A2 adenosine receptor in bovine striatal membranes with high affinity (Kd = 1.5 nM) and A2 receptor selectivity. Competitive binding studies reveal the appropriate A2 receptor pharmacologic potency order with 5'-N-et
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34

González-Lucas, María, Manuel Peinado, Juan J. Vaquero, Leonor Nozal, Juan Luis Aguirre, and Sergio González-Egido. "Microwave-Assisted Pyrolysis of Leather Waste." Energies 15, no. 4 (2022): 1273. http://dx.doi.org/10.3390/en15041273.

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The processing of leather into leather is one of the oldest known manufacturing practices. The subsequent refinement of this technique over recent centuries has led to an increase in production, which in turn has led to an increase in waste production. Today, many of the by-products and waste streams from the leather industry have applications in industries such as petfood and in the production of collagen and derivatives, while others, such as waste from trimming and scraping the material, are disposed of in landfills, causing a detrimental environmental impact. For this reason, new alternati
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35

Deoghare, Chetana. "Experimental determination of activation rate constant and equilibrium constant for bromo substituted succinimide initiators for an atom transfer radical polymerization process." Pure and Applied Chemistry, March 17, 2022. http://dx.doi.org/10.1515/pac-2021-2012.

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Abstract Alkyl bromides are used as initiators in most of the atom transfer radical polymerization (ATRP) process and play an important role for controlling the ATRP equilibrium. In this work, the effect of solvent on equilibrium constant of ATRP (K ATRP) and rate constant of activation (k act) of three isomeric alkyl bromides [namely, N-phenyl(3-bromo-3-methyl)succinimide, N-phenyl(3-bromo-4-methyl)succinimide, and N-phenyl(3-bromomethyl)succinimide] is reported. The k act and K ATRP values of alkyl bromide are determined experimentally using UV–Vis-NIR spectrometry. The termination rate cons
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36

Hu, Lin‐Ping, De‐Run Zhang, Feng‐Lin Liu, et al. "Metal‐Free Visible‐Light‐Promoted Haloazidation/Cyclization of Phenyl‐Linked 1,6‐Enynes with TMSN3 and NIS/NBS**." ChemistrySelect 8, no. 29 (2023). http://dx.doi.org/10.1002/slct.202301989.

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AbstractA metal‐ and oxidant‐free procedure for the three‐component haloazidation/cyclization of phenyl‐linked 1,6‐enynes with TMSN3 and N‐iodo(bromo)succinimide under the irradiation of visible light was described. Moreover, this reaction involved a radical addition/5‐exo‐dig cyclization/radical coupling process, and realized simultaneous construction of C−N, C−C, and C−X (I, Br) bonds in one step.
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37

Bogza, S. L., A. A. Malienko, S. Yu Suikov, K. I. Kobrakov, and V. I. Dulenko. "Acylation Products of N-Phenyl-2-(5-tert-butyl-2-thienyl)succinimide." ChemInform 34, no. 5 (2003). http://dx.doi.org/10.1002/chin.200305118.

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38

Ali, Ola A. Abu, M. M. Elsawy, and Ahmed A. El-Henawy. "New eco-friendly succinimide linseed oil resin: synthesis, characterization, DFT and docking studies for surface coating." Pigment & Resin Technology, November 18, 2024. http://dx.doi.org/10.1108/prt-05-2024-0052.

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Purpose The purpose of this study is to develop a new protective coating formulation for industrial use, using new eco-friendly succinimide linseed oil resin. Design/methodology/approach Epoxidized linseed oil and N-(4-hydroxy phenyl) succinimide are reacted to create succinimide-modified epoxy (SIE) compounds. The synthesized compound was confirmed by different analyses, gas chromatography, Fourier transform infrared, proton nuclear magnetic resonance and scanning electron microscopy. The prepared compound has been blended with a primer paint formulation, then their physical and mechanical pr
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Bankar, Onkar S., Debasish Laha, Kajal B. Meher та Ramakrishna G. Bhat. "Umpolung Reactivity of Diazo Arylidene Succinimides: Distal C–H Functionalization of α‐Thiocarbonyls from the Reactive Carbenoid Center". Chemistry – An Asian Journal, 12 жовтня 2023. http://dx.doi.org/10.1002/asia.202300774.

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Herein, for the first time we have explored the umpolung reactivity of vinylogous carbon center of diazo arylidene succinimide (DAS) through rhodium catalysis to achieve [2,3]‐Stevens rearrangement of α‐thioether esters. The protocol has successfully demonstrated the distal C‐H bond functionalization of the α‐thioether esters. Alongside, the carbenoid reactivity of DAS has also been achieved with Doyle‐Kirmse reaction of allyl/propargyl phenyl sulfides. The protocol proved to be practical to synthesize a wide variety of [2,3]‐Stevens rearrangement products exclusively and the possible side pro
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Assy, Habib, Uttam Kumar Mishra, Tom Rösler, Raman Khurana, N. Gabriel Lemcoff, and Ofer Reany. "Stereospecific Radical Bromination of ß‐Aryl Alcohols with Thiourea Additives Through A Serendipitous Discovery of A 1,2‐Aryl Migration." Chemistry – A European Journal, January 2, 2025. https://doi.org/10.1002/chem.202403831.

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The development of new protocols for stereospecific and stereoselective halogenation transformations by mild reaction conditions is a highly desirable research target for the chemical and pharmaceutical industries. Following the straightforward methodology for directly transforming a wide scope of alcohols to alkyl bromides and chlorides using substoichiometric amounts of thioureas and N‐halo succinimides (NXS) as a halogen source in a single step, we noticed that in apolar solvents bromination of chiral secondary alcohols did not produce the expected racemates. In this study, the stereochemic
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Deshmukh, Ganesh B., Nilesh S. Patil, Anant B. Kanagare, and Dattatraya N. Pansare. "A facile halogen assisted intramolecular cyclization of (E)‐3‐(substituted benzylidene)‐1‐(substituted phenyl)pyrrolidine‐2,5‐dione." Journal of Heterocyclic Chemistry, May 10, 2024. http://dx.doi.org/10.1002/jhet.4834.

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AbstractA straightforward method for producing pyrrolo‐chromenes involved the utilization of a Wittig reaction, where maleimides reacted with ortho‐hydroxy benzaldehyde. This reaction yields ortho‐hydroxy benzylidine succinimides, which subsequently undergo molecular bromine‐induced intramolecular cyclization, resulting in (E)‐3‐(substituted benzylidine)‐1‐(substituted phenyl) pyrrolidine‐2,5‐dione derivatives (6g‐n). The traditional reaction methods demonstrates efficient performance when carried out in a DMF solvent. This approach proves to be user‐friendly and provides numerous benefits, in
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Qayyum, Muhammad Imran, Sami Ullah, Umer Rashid, et al. "N-phenyl and N-benzyl substituted succinimides: Preclinical evaluation for their antihypertensive effect and underlying mechanism." European Journal of Pharmacology, December 2023, 176195. http://dx.doi.org/10.1016/j.ejphar.2023.176195.

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Sharma, Shweta, Chirag Sharma, Bhawana Thadhaney, and G. L. Talesara. "ChemInform Abstract: Synthesis of Phthalimido or Succinimido [2-aryl-4-oxo-3-{2-phenyl-4 (3H)-quinazolinon-3-yl}-1,3-thiazolidin-5-yl]ethanoate." ChemInform 41, no. 2 (2010). http://dx.doi.org/10.1002/chin.201002177.

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Wang, Li-Xin, Wen-Sheng Li, guo cheng, Jian Zhang, sen lu, and Wen-Juan wan. "A Copper Catalyzed Doyle−Kirmse Reaction between Vinyl Diazosuccinimide and Allyl-Phenyl Thioetherfor the Concise and Effective Preparation of Multifunctional 3-Allyl-3-(Thio) Succinimides." SSRN Electronic Journal, 2023. http://dx.doi.org/10.2139/ssrn.4388512.

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Mo, Shuyuan, Ziming Zhao, Zi Ye, et al. "New secondary metabolites with cytotoxicity from fungus Penicillium roqueforti." Natural Products and Bioprospecting 13, no. 1 (2023). http://dx.doi.org/10.1007/s13659-023-00381-4.

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AbstractTwo novel compounds including a cyclohelminthol type polyketide (namely oxaleimide K, 1) and a maleimide derivative (namely peniroquefortine A, 2), and a new natural product (namely 2-(acetylamino)-N-[(1E)-2-phenylethenyl]-acetamide, 3), together with four known compounds (4–7), were isolated and identified from fungus Penicillium roqueforti, which was separated from the root soil of Hypericum beanii N. Robson collected from the Shennongjia Forestry District, Hubei Province. Their structures including absolute configurations were mainly established by the NMR spectroscopy analyses and
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sprotocols. "Tandem affinity purification of remodeler-mononucleosome complexes for ChIP-seq in mouse embryonic stem cells." December 31, 2014. https://doi.org/10.5281/zenodo.13668.

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Authors: Arnaud Depaux, Maud de Dieuleveult, Isabelle Hmitou, Sylvie Jounier, Hélène Humbertclaude &amp; Matthieu Gerard ### Abstract This protocol describes a tandem affinity chromatin immunopurification strategy to analyze the distribution of chromatin remodelers onto the mouse genome. It is based on mouse embryonic stem (ES) cell lines that express, from the endogenous loci, remodelers fused with a tandem affinity purification (TAP)-tag. Two versions of the TAP-tag, introduced at the C terminus, have been used successfully: (FLAG3-TEV-HA) and (FLAG-HA). ES cells are first fixed either with
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sprotocols. "Imaging and Analysis of OT1 T Cell Activation on Lipid Bilayers." January 7, 2015. https://doi.org/10.5281/zenodo.13784.

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Authors: Peter Beemiller, Jordan Jacobelli &amp; Matthew Krummel ### Abstract Supported lipid bilayers are frequently used to study cell membrane protein dynamics during immune synapse formation by T cells. Here we describe methods for the imaging and analysis of OT1+ T cell activation and T-cell receptor (TCR) dynamics on lipid bilayers. ### Introduction T cells are activated at immune synapses when TCRs bind agonist ligands on antigen presenting cells (APCs). Glass coverslip–supported lipid bilayers provide a system for in vitro T cell activation and immune synapse formation. In these system
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