Relevant bibliographies by topics / Phenylacetic acid amide

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Academic literature on the topic 'Phenylacetic acid amide'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Phenylacetic acid amide"

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Castiñeiras, Alfonso, Antonio Frontera, Isabel García-Santos, Josefa M. González-Pérez, Juan Niclós-Gutiérrez, and Rocío Torres-Iglesias. "Multicomponent Solids of DL-2-Hydroxy-2-phenylacetic Acid and Pyridinecarboxamides." Crystals 12, no. 2 (2022): 142. http://dx.doi.org/10.3390/cryst12020142.

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We prepared cocrystals of DL-2-Hydroxy-2-phenylacetic acid (D, L-H2ma) with the pyridinecarboxamide isomers, picolinamide (pic) and isonicotinamide (inam). They were characterized by elemental analysis, single crystal and powder X-ray, IR spectroscopy and 1H and 13C NMR. The crystal and molecular structures of (pic)-(D-H2ma) (1), (nam)-(L-H2ma) (2) and (inam)-(L-H2ma) (3) were studied. The crystal packing is stabilized primarily by hydrogen bonding and in some cases through π-π stacking interactions. The analysis of crystal structures reveals the existence of the characteristic heterosynthons
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2

Anenko, D., I. Kodonidi, A. Glushko, A. Chiriapkin, L. Smirnova, and A. Ivchenko. "N-acylation of Phenylacetic Acid Amide - Synthesis and Study of Thermodynamic Reaction Characteristics." Bulletin of Science and Practice 6, no. 1 (2020): 10–13. https://doi.org/10.33619/2414-2948/50/01.

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The aim of this study is the synthesis of N-acylated derivatives of phenylacetic acid amide and the investigation of the correlation between product yields and the nature of the acylating agent. The reaction was carried out in an acidic environment, adding acid anhydrides to the substance, which differ in the length and branching of the carbon chain. The resulting products are of considerable interest both as biologically active compounds and as starting materials for the preparation of pyrimidin-4(1)-one derivatives.
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Anenko, D., I. Kodonidi, D. Glushko, A. Chiriapkin, L. Smirnova, and A. Ivchenko. "N-acylation of Phenylacetic Acid Amide - Synthesis and Study of Thermodynamic Reaction Characteristics." Bulletin of Science and Practice 6, no. 1 (2020): 10–13. http://dx.doi.org/10.33619/2414-2948/50/01.

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The aim of this study is the synthesis of N-acylated derivatives of phenylacetic acid amide and the investigation of the correlation between product yields and the nature of the acylating agent. The reaction was carried out in an acidic environment, adding acid anhydrides to the substance, which differ in the length and branching of the carbon chain. The resulting products are of considerable interest both as biologically active compounds and as starting materials for the preparation of pyrimidin-4(1)-one derivatives.
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4

Król, Marek, Grzegorz Ślifirski, Jerzy Kleps, et al. "The Synthesis and Absolute Configuration of Enantiomeric Pure (R)- and (S)-3-(piperidin-3-yl)-1H-Indole Derivatives." International Journal of Molecular Sciences 24, no. 1 (2022): 517. http://dx.doi.org/10.3390/ijms24010517.

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This article describes the synthesis of new chiral 3-(piperidin-3-yl)-1H-indole derivatives (R)-10a-c and (S)-11a-c from the corresponding diastereomers: (3R, 2R) and (3S, 2R)-2-[3-(1H-indol-3-yl)-1-piperidyl]-2-phenyl-acetamides (3R, 2R)-4a, (3R, 2R)-6b, (3R, 2R)-8c and (3S, 2R)-5a, (3S, 2R)-7b, (3S, 2R)-9c. Diastereomers were obtained by N-alkylation of derivatives of racemic 3-(piperidin-3-yl)-1H-indoles 1a-c using (S)-2-(4-toluenesulfonyloxy)-phenylacetic amide (S)–II. The same method was applied to obtain (3R, 2S)-methyl-2-[3-(1H-indole-3-yl)-1-piperidyl]-2-phenylacetate (3R, 2S)-2a and (
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5

Basso, Alessandra, Luigi De Martin, Cynthia Ebert, Lucia Gardossi, and Paolo Linda. "Selectivity of penicillin G acylase towards phenylacetic acid derivatives in amide bond synthesis in toluene." Journal of Molecular Catalysis B: Enzymatic 16, no. 2 (2001): 73–80. http://dx.doi.org/10.1016/s1381-1177(01)00047-9.

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6

Kodonidi, I. P., D. S. Anenko та D. I. Pozdnyakov. "Synthesis and Action of N-acylphenylacetamides and N-acyl-β-ketoamides on the Central Nervous System". Drug development & registration 11, № 1 (2022): 40–49. http://dx.doi.org/10.33380/2305-2066-2022-11-1-40-49.

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Introduction. One of the most promising directions in the search for biologically active compounds is the molecular design of biologically active compounds containing a known pharmacoform fragment. In this article, phenylacetic acid derivatives are considered as a scaffold for the search for biologically active compounds. However, the phenylacetamide derivative is of particular interest, its fragment is included in the structure of the atenolol drug. Optimization of methods for the synthesis of N-acylphenylacetamides and N-acyl-β-ketoamides will expand the boundaries of molecular design and ta
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7

MATSUO, Jun-ichi, and Kenji KOGA. "Enantioselective .ALPHA.-Alkylation of Phenylacetic Acid Using a Chiral Bidentate Lithium Amide as a Chiral Auxiliary." CHEMICAL & PHARMACEUTICAL BULLETIN 45, no. 12 (1997): 2122–24. http://dx.doi.org/10.1248/cpb.45.2122.

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8

MATSUO, J., та K. KOGA. "ChemInform Abstract: Enantioselective α-Alkylation of Phenylacetic Acid Using a Chiral Bidentate Lithium Amide as a Chiral Auxiliary." ChemInform 29, № 22 (2010): no. http://dx.doi.org/10.1002/chin.199822033.

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9

Fotopoulos, Ioannis, Eleni Pontiki, and Dimitra Hadjipavlou Litina. "Targeting Inflammation with Conjugated Cinnamic Amides, Ethers and Esters." Letters in Drug Design & Discovery 17, no. 1 (2019): 3–11. http://dx.doi.org/10.2174/1570180816666181129125511.

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Background: Cinnamic acid is a key intermediate in shikimate and phenylpropanoid pathways. It is found both in free form, and especially in the form of esters in various essential oils, resins and balsams which are very important intermediates in the biosynthetic pathway of several natural products. The cinnamic derivatives play a vital role in the formation of commercially important intermediate molecules which are necessary for the production of different bioactive compounds and drugs. Different substitutions on basic moiety lead to various biological activities. Furthermore, combination of
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10

Panoutsopoulos, Georgios I. "Phenylacetaldehyde Oxidation by Freshly Prepared and Cryopreserved Guinea Pig Liver Slices: The Role of Aldehyde Oxidase." International Journal of Toxicology 24, no. 2 (2005): 103–9. http://dx.doi.org/10.1080/10915810590936373.

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Phenylacetaldehyde is formed when the xenobiotic and biogenic amine 2-phenylethylamine is inactivated by a monoamine oxidase–catalyzed oxidative deamination. Exogenous phenylacetaldehyde is found in certain foodstuffs such as honey, cheese, tomatoes, and wines. 2-Phenylethylamine can trigger migraine attacks in susceptible individuals and can become fairly toxic at high intakes from foods. It may also function as a potentiator that enhances the toxicity of histamine and tyramine. The present investigation examines the metabolism of phenylacetaldehyde to phenylacetic acid in freshly prepared an
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Book chapters on the topic "Phenylacetic acid amide"

1

Taber, Douglass F. "Substituted Benzenes: The Reddy Synthesis of Isofregenedadiol." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0062.

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Jianbo Wang of Peking University (Org. Lett. 2011, 13, 4988) and Patrick Y. Toullec and Véronique Michelet of Chimie ParisTech (Org. Lett. 2011, 13, 6086) developed conditions for the electrophilic acetoxylation of a benzene derivative 1. Seung Hwan Cho and Sukbok Chang of KAIST (J. Am. Chem. Soc. 2011, 133, 16382) and Brenton DeBoef of the University of Rhode Island (J. Am. Chem. Soc. 2011, 133, 19960) devised protocols for the electrophilic imidation of a benzene derivative 3. Vladimir V. Grushin of ICIQ Tarragona devised (J. Am. Chem. Soc. 2011, 133, 10999) a simple protocol for the cyanati
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Conference papers on the topic "Phenylacetic acid amide"

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Ladyka, A. A., A. V. Sosnovskaya, M. V. Chernikov, and D. I. Pozdnyakov. "ANTIAPOPTOTIC EFFECT OF PHENYLACETIC ACID AMIDE DERIVATIVES. EVALUATION OF THE STRUCTURE-ACTIVITY RELATIONSHIP." In MedChem-Russia 2021. 5-я Российская конференция по медицинской химии с международным участием «МедХим-Россия 2021». Издательство Волгоградского государственного медицинского университета, 2021. http://dx.doi.org/10.19163/medchemrussia2021-2021-363.

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