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Dissertations / Theses on the topic 'Phenylacetic acids'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Tchibouanga, Remi Rolland Ngoma. "Salts and cocrystals of substituted phenylacetic acids." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2857.

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Thesis (Master of Applied Science in Chemistry)--Cape Peninsula University of Technology, 2018.<br>The prediction of the single crystal structure that will form due to the combination of two or more compounds to form a multicomponent crystal is one of the important areas of research in crystal engineering. Since these compounds display different properties when combined as a single crystal, knowledge of synthesis and design of the resulting compound is essential. The formation of a multicomponent crystal, such as a salt or a cocrystal generally depends on the complementarity of the functional

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2

Tischler, Dirk, Michel Oelschlägel, Juliane Zimmerling, and Michael Schlömann. "Neue Wege in der Weißen Biotechnologie." Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2016. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-210778.

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Mikroorganismen sind in der Lage, zahlreiche Xenobiotika abzubauen. Dazu nutzen sie unter aeroben Bedingungen oft einleitend Oxygenasen. Durch diese kann molekularer Luftsauerstoff aktiviert und auf organische Moleküle übertragen werden. Danach können die Verbindungen in den Metabolismus der Mikroorganismen eingeschleust und teils oder vollständig abgebaut werden. Am Beispiel des Styrols zeigen wir hier eine solche Abbauroute und wie wir diese biotechnologisch nutzen können, um interessante Verbindungen zu synthetisieren. Zielmoleküle der gesamten Enzymkaskade sind dabei diverse Phenylessigsäu

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3

Tischler, Dirk, Michel Oelschlägel, Juliane Zimmerling, and Michael Schlömann. "Neue Wege in der Weißen Biotechnologie." TU Bergakademie Freiberg, 2015. https://tubaf.qucosa.de/id/qucosa%3A23081.

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Mikroorganismen sind in der Lage, zahlreiche Xenobiotika abzubauen. Dazu nutzen sie unter aeroben Bedingungen oft einleitend Oxygenasen. Durch diese kann molekularer Luftsauerstoff aktiviert und auf organische Moleküle übertragen werden. Danach können die Verbindungen in den Metabolismus der Mikroorganismen eingeschleust und teils oder vollständig abgebaut werden. Am Beispiel des Styrols zeigen wir hier eine solche Abbauroute und wie wir diese biotechnologisch nutzen können, um interessante Verbindungen zu synthetisieren. Zielmoleküle der gesamten Enzymkaskade sind dabei diverse Phenylessigsäu

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4

Levandowski, Mariana Negrelli. "ESTUDO CONFORMACIONAL DE DERIVADOS DO ÁCIDO FENILACÉTICO EMPREGANDO CÁLCULOS TEÓRICOS E AS ESPECTROSCOPIAS DE RESSONÂNCIA MAGNÉTICA NUCLEAR E INFRAVERMELHO." UNIVERSIDADE ESTADUAL DE PONTA GROSSA, 2017. http://tede2.uepg.br/jspui/handle/prefix/12.

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Made available in DSpace on 2017-07-20T12:40:20Z (GMT). No. of bitstreams: 1 Mariana_N_Levandowski.pdf: 3613595 bytes, checksum: 6d13f04a1872ade8572c9eae481770c6 (MD5) Previous issue date: 2017-02-13<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study presents a theoretical and experimental analysis of the conformational equilibrium of phenylacetic acid and its derivatives, namely: o-fluorophenylacetic, ochlorophenylacetic, o-bromophenylacetic, o-nitrophenylacetic, hydroxyphenylacetic, m-fluorophenylacetic, p-fluorophenylacetic, p-nitrophenylacetic, p-hydroxyphenylac

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5

Mei-hua, Shiu, and 徐美華. "Effect of Phenylacetic Acid Analogs on Differentiation." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/33940116784148282010.

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碩士<br>中國醫藥學院<br>藥物化學研究所<br>89<br>In order to develop the novel cell differentiation agents, a series of phenylacetic acid analogs was screened for their differentiation and anti-proliferation activities of HL-60 cells. Compounds 10-1 and 11-1 were found to be the most effective to differentiate and to be the most effective to potentate the induction of differentiation by all-trans retinoic acid (ATRA). Therefore the further studies were carried out to evaluate their effects on the cell cycle and cell surface antigen expression of HL-60 cells. When treatment of compounds 10-1 and 11-

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6

Law, Adrienne. "Structural and functional characterization of PaaK1 & PaaK2: phenylacetate CoA ligase paralogs from Burkholderia cenocepacia J2315." Thesis, 2010. http://hdl.handle.net/1828/3613.

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Aromatic compounds comprise approximately 25% of the Earth`s biomass. Accordingly, turnover of these thermostable compounds is essential to the biogeochemical carbon cycle. Specialized microbial enzymatic pathways are largely responsible for mineralization of aromatic compounds, and are extensively studied for bioremediation purposes. The phenylacetic acid degradation pathway (PAA) is of particular interest as it is utilized for degradation of a multitude of aromatic compounds, including environmental pollutants, and appears to be widely distributed among bacteria. Intriguingly, the PAA pathwa

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7

Hamlin, Jason. "Regulation of phenylacetic acid degradation in Burkholderia cenocepacia K56-2." 2009. http://hdl.handle.net/1993/21488.

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8

Liu, Su Zhen, and 劉夙真. "Synthesis of substituted phenylacetic acid derivatives as cell differentiation inducer." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/99151209257262803502.

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9

Cook, SD. "A comparison of the biosynthesis of indole-3-acetic acid and phenylacetic acid." Thesis, 2018. https://eprints.utas.edu.au/28357/1/Cook_whole_thesis.pdf.

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The biosynthesis of the auxin, indole-3-acetic acid (IAA), has been well studied in recent years. It is now accepted that the indole-3-pyruvate (IPyA) pathway is the main IAA biosynthetic route and is responsible for the majority of IAA produced in plants. This pathway involves the transamination of the amino acid, tryptophan (Trp), to IPyA by the TAR (TRYPTOPHAN AMINOTRANSFERASE RELATED) enzymes, followed by the oxidative decarboxylation of IPyA to IAA by the YUCCA proteins. Recently it has been suggested that the TARs and the YUCCAs are also responsible for the biosynthesis of a less well-s

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10

Pribytkova, Tatiana. "The attenuated virulence of a Burkholderia cenocepacia K56-2 paaABCDE mutant is due to inhibition of quorum sensing by release of phenylacetic acid." 2014. http://hdl.handle.net/1993/23961.

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The phenylacetic acid degradation pathway of Burkholderia cenocepacia is necessary for full pathogenicity of B. cenocepacia in nematode; however, the reasons of such requirements are unknown. Unlike wild type B. cenocepacia, a deletion mutant of the phenylacetyl-CoA monooxygenase complex (ΔpaaABCDE) released phenylacetic acid extracellularly in conditions that allow infection in Caenorhabditis elegans. Addition of phenylacetic acid further decreased the pathogenicity of the ΔpaaABCDE, which cannot metabolize phenylacetic acid, but did not affect the wild type, due to phenylacetic acid consumpt

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11

Wu, Huai-En, and 吳懷恩. "Kinetic study On The Esterification of Benzenedicarboxylic acid and Substituted Phenylacetic acid By Solid-Liquid Phase-Transfer Catalysis." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/29246843380486099206.

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碩士<br>國立中興大學<br>化學系<br>87<br>英文摘要 The phase-transfer Catalysis (PTC) technique greatly enhances the reaction rates of various organic reations under mild conditions in multiphase systems. The objectives of the present study are to apply solid-liquid phase-transfer catalytic technique in systhesizing diesters and ether-esters by conducting nucleophilic substitutions in the organic solution, and to study the reaction kinetics. The systheses of dibenzyl phthalate (DBP)and diallyl phthalate (DAP) were conducted from potassium phthalate with benzyl bromide and allyl bromide ,respectively

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12

Chan, Hsu-Chin, and 詹淑秦. "Growth Inhibitory Effects of Synthetic Phenylacetic acid Derivatives on Human Squamous Lung Cancer CH27 Cells." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/91901976034264732173.

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博士<br>中國醫藥學院<br>藥物化學研究所<br>91<br>Phenylacetic acid is a differentiation inducer, has anticancer activity with relatively low toxicity. In the present study, we examined the anticancer effect of series synthetic phenylacetic acid derivatives in human lung cancer cells for searching more effective phenylacetic acid analogous. Results shown that the antiproliferative effects of these synthetic compounds were stronger than those of phenylacetic acid, and that 4-fluoro-N-butyl phenylacetamide (H6) and 2-fluoro-N-butyl-phenyl- acetamide (SCK6) are the most potent compounds. To address the mechani

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13

Yang, Ya-Ju, and 楊雅茹. "Growth inhibitory effects of synthetic phenylacetatic acid derivatives on human cervical cancer cells." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/19107269702958774579.

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碩士<br>中國醫藥大學<br>醫學研究所<br>92<br>Abstract Phenylacetate was found to induce tumor cytostasis and differentiation through several mechanisms. In this study, we investigated the activity of the synthetic phenylacetate derivatives treatment of human cervical cancer cells, Hela-S3 and Ca Ski cells. The two synthetic phenylacetate derivatives are 4-Fluoro-N-butylphenylacetamides (H6) and 2-Fluoro-N -Butylphenylacetamides (SCK6). Results showed that the anti -proliferative and apoptosis effects of these two synthetic compounds, and with a dose- and time-dependent response. The IC50 valu

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14

Law, Robyn Jamie. "The relationship between phenylacetic acid catabolism and pathogenicity of Burkholderia cenocepacia K56-2 in the Caenorhabditis elegans host model." 2009. http://hdl.handle.net/1993/21343.

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15

Panoutsopoulos, Georgios I., E. G. Gounaris, D. Kouretas, and Christine Beedham. "Enzymatic oxidation of 2-phenylethylamine to phenylacetic acid and 2-phenylethanol with special reference to the metabolism of its intermediate phenylacetaldehyde." 2004. http://hdl.handle.net/10454/3259.

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No<br>2-phenylethylamine is an endogenous constituent of the human brain and is implicated in cerebral transmission. This bioactive amine is also present in certain foodstuffs such as chocolate, cheese and wine and may cause undesirable side effects in susceptible individuals. Metabolism of 2-phenylethylamine to phenylacetaldehyde is catalysed by monoamine oxidase B but the oxidation to its acid is usually ascribed to aldehyde dehydrogenase and the contribution of aldehyde oxidase and xanthine oxidase, if any, is ignored. The objective of this study was to elucidate the role of the molybdenum

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