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Journal articles on the topic 'Phenylethanoid glycosides'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Chao, Chien-Liang, Hsin-Wen Huang, Hui-Chi Huang, et al. "Inhibition of Amyloid Beta Aggregation and Deposition of Cistanche tubulosa Aqueous Extract." Molecules 24, no. 4 (2019): 687. http://dx.doi.org/10.3390/molecules24040687.

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Cistanche tubulosa aqueous extract (CTE) is already used as a botanical prescription drug for treating dementia in China. Our previous studies reported that phenylethanoid glycosides of CTE have anti-Alzheimer’s disease (AD) activity by inhibiting amyloid β peptide (Aβ) aggregation and deposition. However, recent studies considered that the phenylethanoid glycosides may be metabolized by intestinal bacteria, because all analysis results showed that the bioavailability of phenylethanoid glycosides is extremely low. In this study we demonstrate how iron chelation plays a crucial role in the Aβ a

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2

Budzianowska, Anna, Ewa Totoń, Aleksandra Romaniuk-Drapała, Małgorzata Kikowska, and Jaromir Budzianowski. "Cytotoxic Effect of Phenylethanoid Glycosides Isolated from Plantago lanceolata L." Life 13, no. 2 (2023): 556. http://dx.doi.org/10.3390/life13020556.

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The aim of the study is to investigate whether the bioactive compounds isolated from P. lanceolata inflorescences, namely, phenylethanoid glucosides, acteoside, plantamajoside, and a flavonoid, isorhamnetin-3-O-rutinoside-4′-O-glucoside, possessed cytotoxic activity against the selected cancer cell lines. The potential antitumor effects of two phenylethanoid glycosides and one flavonoid were evaluated via MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay on seven human carcinoma cell lines (MCF-7, MDA-MB-231, Caco-2, HepG2, OVCAR-3, U138-MG, U251-MG) and one nontumorigen

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3

Bankova, Vassya, Jordanka Koeva-Todorovska, Tatyana Stambolijska, Maria-Desislava Ignatova-Groceva, Daniela Todorova, and Simeon Popov. "Polyphenols in Stachys and Betonica Species (Lamiaceae)." Zeitschrift für Naturforschung C 54, no. 11 (1999): 876–80. http://dx.doi.org/10.1515/znc-1999-1104.

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Abstract Above-ground parts and roots from four Stachys species (S. germanica L., S. sylvatica L. and the Balkan endemics S. thracica Dav. and S. plumosa Griseb.) as well as o f three Betonica species (B. officinalis L. and the Balkan endemics B. bulgarica Deg. et Neic. and B. scardica Griseb.) were screened for phenols (phenylethanoid glycosides, flavonoid glycosides and the phenolic diterpene betolide). Three phenylethanoid glycosides, a flavonoid glycoside and the phenolic diterpene betolide were isolated and identified, most of them for the first time in the investigated species. The resul

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4

Homova, Vediha, Jost Weber, Josef Schulze, Kalina Alipieva, Thomas Bley, and Milen Georgiev. "Devil’s Claw Hairy Root Culture in Flasks and in a 3-L Bioreactor: Bioactive Metabolite Accumulation and Flow Cytometry." Zeitschrift für Naturforschung C 65, no. 7-8 (2010): 472–78. http://dx.doi.org/10.1515/znc-2010-7-809.

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Phenylethanoids are a group of natural water-soluble compounds with high biological value, which could potentially be commercially produced by hairy root cultures. Thus, we have examined the capacity of transformed root cultures of Devil’s claw (Harpagophytum procumbens) to accumulate four phenylethanoid glycosides - β-OH-verbascoside, verbascoside, leucosceptoside A, and martynoside - in shake-flasks and a 3-L stirred tank reactor. Verbascoside was found to be the major phenylethanoid, and its maximal contents were the same (1.12 mg/g dry weight) in both kinds of culture. However, peak leucos

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5

Çalis, Ihsan, Hasan Kirmizibekmez, Heinz Rüegger, and Otto Sticher. "Phenylethanoid Glycosides fromGlobulariatrichosantha." Journal of Natural Products 62, no. 8 (1999): 1165–68. http://dx.doi.org/10.1021/np9900526.

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6

Nazemiyeh, Hossein, Abbas Delazar, Mohammed-Ali Ghahramani, Amir-Hossein Talebpour, Lutfun Nahar, and Satyajit D. Sarker. "Phenolic Glycosides from Phlomis lanceolata (Lamiaceae)." Natural Product Communications 3, no. 1 (2008): 1934578X0800300. http://dx.doi.org/10.1177/1934578x0800300112.

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Preparative reversed-phase HPLC analyses of the methanol extract of the aerial parts of Phlomis lanceolata afforded three phenolic glycosides including a flavonol glycoside, peterin (1), and two phenylethanoid glycosides, viridoside (2) and peteroside (3). Compounds 1 and 3 are novel natural products. The structures of all three compounds were elucidated by spectroscopic means.

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7

Kırmızıbekmez, Hasan, Carla Bassarello, Sonia Piacente, Galip Akaydın, and İhsan Çalış. "Flavonoid, Phenylethanoid and Iridoid Glycosides from Globularia aphyllanthes." Zeitschrift für Naturforschung B 64, no. 2 (2009): 252–56. http://dx.doi.org/10.1515/znb-2009-0217.

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A new flavone glycoside, 6-hydroxyluteolin 7-O-[6m-benzoyl-β -D-glucopyranosyl-(1 → 2)]-β - D-glucopyranoside (aphyllanthoside, 1) was isolated from the MeOH extract of the aerial parts of Globularia aphyllanthes. Besides this new compound, two flavonoid glycosides (6-hydroxyluteolin 7-O-[6m-(E)-caffeoyl-β -D-glucopyranosyl-(1 → 2)]-β -D-glucopyranoside and isoquercitrin), three phenylethanoid glycosides (verbascoside, rossicaside A, and trichosanthoside A), and 11 iridoid glycosides (aucubin, catalpol, 10-O-benzoylcatalpol, globularin, asperuloside, besperuloside, asperulosidic acid, daphyllo

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8

Calis, Ihsan, Hasan Kirmizibekmez, Tayfun Ersoz, Ali A. Dönmez, Charlotte H. Gotfredsen, and Søren R. Jensen. "Iridoid Glucosides from Turkish Phlomis tuberosa." Zeitschrift für Naturforschung B 60, no. 12 (2005): 1295–98. http://dx.doi.org/10.1515/znb-2005-1214.

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From the aerial parts of Phlomis tuberosa a new iridoid glucoside, chlorotuberoside was isolated together with five known iridoid glucosides, lamalbide, shanzhiside methyl ester, 7-epi-phlomiol (= phloyoside I), sesamoside and 5-deoxysesamoside. Two known phenylethanoid glycosides, forsythoside B, and decaffeoylacteoside, three known neolignan glycosides, dehydrodiconiferyl alcohol 9’-O-β -D-glucopyranoside, dihydrodehydrodiconiferyl alcohol 9-O-β -D-glucopyranoside and dihydrodehydrodiconiferyl alcohol 9’-O-β -D-glucopyranoside, one flavone glycoside, luteolin 7-O-β - D-glucopyranoside, as we

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9

Li, Pengfei, Meng Qi, Haijun Hu, et al. "Structure–inhibition relationship of phenylethanoid glycosides on angiotensin-converting enzyme using ultra-performance liquid chromatography-tandem quadrupole mass spectrometry." RSC Advances 5, no. 64 (2015): 51701–7. http://dx.doi.org/10.1039/c5ra05027h.

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The structure–inhibition relationship of phenylethanoid glycosides against ACE was investigated by an improved UPLC-MS/MS method. The number of hydroxyl groups and structural steric hindrance were critical for the ACEI of phenylethanoid glycosides.

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10

Kırmızıbekmez, Hasan, Sonia Piacente, Cosimo Pizza, Ali A. Dönmez, and İhsan Çaliș. "Iridoid and Phenylethanoid Glycosides from Phlomis nissolii and P. capitata." Zeitschrift für Naturforschung B 59, no. 5 (2004): 609–13. http://dx.doi.org/10.1515/znb-2004-0523.

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Abstract A new iridoid glucoside, lamiidic acid was isolated from Phlomis nissolii, along with one known iridoid glucoside, lamiide and 13 phenylethanoid glycosides, verbascoside, isoverbascoside, leucosceptosides A and B, martynoside, arenarioside, forsythoside B, alyssonoside, lamiophlomiside A, samioside, integrifoliosides A and B, and hattushoside. A new iridoid glucoside, ipolamiidic acid was isolated from Phlomis capitata together with two known iridoid glucosides, lamiide and ipolamiide. The known phenylethanoid glycosides, isoverbascoside, forsythoside B, alyssonoside and hattushoside,

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11

Shu, Penghua, Huiqing Zhu, Wanrong Liu, et al. "Isolation and Characterization of Glycosidic Tyrosinase Inhibitors from Typhonium giganteum Rhizomes." Records of Natural Products 15, no. 5 (2021): 380–87. http://dx.doi.org/10.25135/rnp.230.21.02.1965.

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A new hydrocinnamoyl glucoside, 1-O-(4-hydroxyhydrocinnamoyl)-β-D-glucopyranose (1), together with fifteen known glycosides, including two phenylethanoid glycosides (2–3), two cinnamoyl glycosides (4–5), six phenolic glycosides (6–11), one lignan glycoside (12) and four megastigmane glycosides (13–16) were isolated from a 95% EtOH extract of the Typhonium giganteum rhizomes. The sixteen glycosides were structurally characterized by NMR, HRESIMS, enzymatic hydrolysis and comparison with literature. Upon evaluating inhibitory activities of compounds 1–16 against mushroom tyrosinase at 25 μM, com

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12

Saracoglu, Iclal, Mehtap Varel, Junko Hada, et al. "Phenylethanoid Glycosides from Phlomis integrifolia Hub.-Mor." Zeitschrift für Naturforschung C 58, no. 11-12 (2003): 820–25. http://dx.doi.org/10.1515/znc-2003-11-1213.

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Abstract Two new phenylethanoid glycosides integrifoliosides A (2) and B (3), along with a known phenylethanoid glycoside alyssonoside (1) and a flavone glucoside chrysoeriol-7-O-β-ᴅ-glucopyranoside (4) were isolated from the aerial parts of Phlomis integrifolia. The structures of the new compounds were identified as 3,4-dihydroxy-β-phenylethoxy-O-β-ᴅ-apiofuranosyl- (1 →4)-α-ʟ-rhamnopyranosyl-(1 →3)-4-O-feruloyl-β-ᴅ-glucopyranoside (2) and 3-hydroxy-4-methoxy-β-phenylethoxy-O-β-ᴅ-apiofuranosyl-(154)-α-ʟ-rhamnopyranosyl-(1→3)-4-O-feruloyl-β-ᴅ-glucopyranoside (3), on the basis of spectroscopic (

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13

Karioti, Anastasia, Jörg Heilmann, and Helen Skaltsa. "Secondary Metabolites from Marrubium velutinum, Growing Wild in Greece." Zeitschrift für Naturforschung B 60, no. 3 (2005): 328–32. http://dx.doi.org/10.1515/znb-2005-0316.

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From the aerial parts of Marrubium velutinum, two new phenylethanoid glycosides, velutinosides III-IV have been isolated together with four known phenylethanoid glycosides, as well as one new acylated flavone and five known flavonoids. The structures of the isolated compounds were established by means of NMR, MS, and UV spectral analyses

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14

KISIEL, W., and F. PIOZZI. "Phenylethanoid glycosides from Prostanthera melissifolia." Phytochemistry 51, no. 8 (1999): 1083–85. http://dx.doi.org/10.1016/s0031-9422(99)00167-3.

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15

Olivier, D. K., E. A. Shikanga, S. Combrinck, R. W. M. Krause, T. Regnier, and T. P. Dlamini. "Phenylethanoid glycosides from Lippia javanica." South African Journal of Botany 76, no. 1 (2010): 58–63. http://dx.doi.org/10.1016/j.sajb.2009.07.002.

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16

Ayupbek, Amatjan, J. F. Ziyavitdinov, U. J. Ishimov, et al. "Phenylethanoid glycosides from Cistanche tubulosa." Chemistry of Natural Compounds 47, no. 6 (2012): 985–87. http://dx.doi.org/10.1007/s10600-012-0123-6.

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17

Miyase, Toshio, Mie Ishino, Chiko Akahori, Akira Ueno, Yuki Ohkawa, and Hisayuki Tanizawa. "Phenylethanoid glycosides from Plantago asiatica." Phytochemistry 30, no. 6 (1991): 2015–18. http://dx.doi.org/10.1016/0031-9422(91)85059-9.

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18

Sugiyama, Masataka, and Masao Kikuchi. "Phenylethanoid glycosides from Osmanthus asiaticus." Phytochemistry 32, no. 6 (1993): 1553–55. http://dx.doi.org/10.1016/0031-9422(93)85178-t.

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19

Nishibe, Sansei, Michiko Sasahara, Ying Jiao, Chang Lu Yuan, and Toshihiro Tanaka. "Phenylethanoid glycosides from Plantago depressa." Phytochemistry 32, no. 4 (1993): 975–77. http://dx.doi.org/10.1016/0031-9422(93)85238-m.

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20

Suzuki, Noriko, Toshio Miyase, and Akira Ueno. "Phenylethanoid glycosides of Sesamum indicum." Phytochemistry 34, no. 3 (1993): 729–32. http://dx.doi.org/10.1016/0031-9422(93)85348-u.

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21

Aoshima, Hiroaki, Toshio Miyase, and Akira Ueno. "Phenylethanoid glycosides from Veronica persica." Phytochemistry 37, no. 2 (1994): 547–50. http://dx.doi.org/10.1016/0031-9422(94)85097-6.

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22

Miyase, Toshio, Ryouko Yamamoto, and Akira Ueno. "Phenylethanoid glycosides from Stachys officinalis." Phytochemistry 43, no. 2 (1996): 475–79. http://dx.doi.org/10.1016/0031-9422(96)00322-6.

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23

Yan, Xiao-Jie, Gu Zhi-Xin, Pan Zheng-Hong, et al. "Phenylethanoid Glycosides from Callicarpa nudiflora." Chemistry of Natural Compounds 56, no. 3 (2020): 430–32. http://dx.doi.org/10.1007/s10600-020-03055-6.

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24

Cao, Ning, Sheng Hua Cao, Ke Hui Tang, et al. "Total syntheses of four natural phenylethanoid glycosides." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 03 (2024): 379. http://dx.doi.org/10.59467/ijhc.2024.34.379.

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The total syntheses of four bioactive natural phenylethanoid glycosides, Forsythiaside A (1), Forsythiaside E (2), Forsythiaside F (3), and Isoforsythiaside (4), have been described for the 1st time using easily accessible materials through concise reaction sequence of 6-11 steps with overall yields of 3.18~15.51%. Furthermore, interrupted Pummerer reaction-mediated glycosylation was successfully used to accomplish glycosyl block building and aglycone coupling.. KEYWORDS :Total synthesis, Natural products, Phenylethanoid glycosides.

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25

Marchenko, Alexandra, Pavel Kintia, Natalia Mashcenco, Carla Bassarello, Sonia Piacente, and Cosimo Pizza. "Phenylethanoid and Iridoid Glycosides from Veronica Chamaedrys L." Chemistry Journal of Moldova 3, no. 2 (2008): 101–4. http://dx.doi.org/10.19261/cjm.2008.03(2).08.

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Three phenylethanoid glycosides (1, 2, 3) and one iridoid glycoside (4) were isolated from aerial parts of Veronica chamaedrys L. (Scrophulariaceae) for the first time. On the basis of spectral analysis, the structures of these compounds were determined to be acteoside (3,4-dihydroxy-β-phenylethoxy-O-α-L-rhamnopyranosyl-(1→3)-4-O-caffeoyl-β-D-glucopyranoside) (1), ehrenoside (3,4-dihydroxy-β-phenylethoxy-O-α-L-arabinopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→3)-4-O-caffeoyl-β-D-glucopyranoside) (2), chamaedroside (3,4-dihydroxy-β-phenylethoxy-O-α-L-rhamnopyranosyl-(1→3)-4-O-caffeoyl-α-L-arabinopy

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26

Akbay, Pınar, İhsan Çalιş, Jörg Heilmann, and Otto Sticher. "Ionone, Iridoid and Phenylethanoid Glycosides from Ajuga salicifolia." Zeitschrift für Naturforschung C 58, no. 3-4 (2003): 177–80. http://dx.doi.org/10.1515/znc-2003-3-406.

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From the aerial parts of Ajuga salicifolia (L.) Schreber, a new ionone glycoside (3β-hydroxy- 7,8-dihydro-4-oxo-β-ionol-9-O-β-ᴅ-glucopyranoside) was isolated, along with the known compounds, corchoionoside C, 8-O-acetylmioporoside, ajugol, harpagide, 8-O-acetylharpagide, lavandulifolioside and leonosides A and B. This is the first report of the occurrence of ionone glycosides and 8-O-acetylmioporoside in Ajuga species. Ajugol, lavandulifolioside, leonoside A and B were isolated for the first time from Ajuga salicifolia. The structures were elucidated by means of 1D-, 2D-NMR spectroscopy, and H

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27

Xue, Zhenzhen, Renyi Yan, and Bin Yang. "Phenylethanoid glycosides and phenolic glycosides from stem bark of Magnolia officinalis." Phytochemistry 127 (July 31, 2016): 50–62. https://doi.org/10.1016/j.phytochem.2016.03.011.

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Xue, Zhenzhen, Yan, Renyi, Yang, Bin (2016): Phenylethanoid glycosides and phenolic glycosides from stem bark of Magnolia officinalis. Phytochemistry 127: 50-62, DOI: 10.1016/j.phytochem.2016.03.011, URL: http://dx.doi.org/10.1016/j.phytochem.2016.03.011

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28

Li, Jian Xin, Ping Li, Yasuhiro Tezuka, Tsuneo Namba, and Shigetoshi Kadota. "Three phenylethanoid glycosides and an iridoid glycoside from Picrorhiza scrophulariiflora." Phytochemistry 48, no. 3 (1998): 537–42. http://dx.doi.org/10.1016/s0031-9422(98)00030-2.

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29

Li, Mao-xing, Jin Huang, Chao Zhang, et al. "Iridoid glycosides and phenylethanoid glycosides from Phlomis younghusbandii roots." Chemistry of Natural Compounds 47, no. 5 (2011): 848–49. http://dx.doi.org/10.1007/s10600-011-0081-4.

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30

E, Nyamsuren, and Odontuya G. "Chemical structures of phenylethanoid glycosides from Pedicularis species, their biological and pharmacological activities." Bulletin of the Institute of Chemistry and Chemical Technology, Mongolian Academy of Sciences, no. 7 (December 6, 2019): 54–60. http://dx.doi.org/10.5564/bicct.v0i7.1274.

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In this review, we summarized the molecular structure specification of a unique component named as phenylethanoid glycosides from the genus Pedicularis L. and their biological and pharmacological activities. Until now, 40 phenylethanoid glycosides have been isolated and identified from the genus Pedicularis L. We classified the compounds into 4 main groups based on the functional group located at the 4′ position. According to the results of in vitro and in vivo studies, the extract containing phenylethanoid glycosides possesses antioxidative, antibacterial, anti-tumor and anti-fatigue activiti

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31

Lu, Jiang-hai, Xiao-ping Pu, Yan-yun Li, Yu-ying Zhao, and Guang-zhong Tu. "Bioactive Phenylethanoid Glycosides from Buddleia lindleyana." Zeitschrift für Naturforschung B 60, no. 2 (2005): 211–14. http://dx.doi.org/10.1515/znb-2005-0214.

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Nine phenylethanoid glycosides were isolated from Buddleia lindleyana. On the basis of spectral analyses, their structures were elucidated to be acteoside (1), echinacoside (2), citanoside A (3), leucosceptoside A (4), leucosceptoside B (5), pedicularioside A (6), isoacteoside (7), arenariside (8), and a new compound named buddleoside A (9). The eight known compounds were isolated from this plant for the first time. The neuroprotective effects of compounds 1 (acteoside), 5, 6, 8 and 9 on the 1-methyl-4-phenylpyridinium ion (MPP+)-induced cell death in mesencenphalic neurons were investigated.

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32

Jin, Qinglong, Hong-Guang Jin, Ji-Eun Shin, Jong-Ki Hong, and Eun-Rhan Woo. "Phenylethanoid Glycosides from Digitalis purpurea L." Bulletin of the Korean Chemical Society 32, no. 5 (2011): 1721–24. http://dx.doi.org/10.5012/bkcs.2011.32.5.1721.

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33

Wong, Ivan Yuen Fan, Zheng-Dan He, Yu Huang, and Zhen-Yu Chen. "Antioxidative Activities of Phenylethanoid Glycosides fromLigustrumpurpurascens." Journal of Agricultural and Food Chemistry 49, no. 6 (2001): 3113–19. http://dx.doi.org/10.1021/jf0100604.

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34

ZOU, Jie-Ming, Li-Sheng WANG, Xue-Mei NIU, Han-Dong SUN, and Ya-Jian GUO. "Phenylethanoid Glycosides from Picria felterrae Lour." Journal of Integrative Plant Biology 47, no. 5 (2005): 632–36. http://dx.doi.org/10.1111/j.1744-7909.2005.00082.x.

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35

Yue, Tan Hor, Anthony Ho Siong Hock, Lim Chan Kiang, and Lim Yang Mooi. "Phenylethanoid Glycosides Isolated from Paraboea Paniculata." Natural Product Communications 7, no. 6 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700621.

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Phytochemical studies of the leaves and rhizomes of Paraboea pa niculata (Gesneriaceae) are reported for the first time. Three phenylethanoid glycosides were isolated and characterized as 3,4-dihydroxyphenethyl-(3″- O-β-D-apiofuranosyl)- β-D-glucopyranoside, calceoralarioside E, and acteoside. These isolates exhibited weak cytotoxic activity against the K-562 cell line with a 50% of cell killing rate of 40.18 μM, 27.05 μM, and 27.24 μM, respectively. In the DPPH free radical scavenging assay, their IC50 values were determined as 75.89 μM, 25.00 μM, and 26.04 μM, respectively.

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36

Ersöz, Tayfun, Wolfgang Schühly, Simeon Popov, Nedjalka Handjieva, Otto Sticher, and Ihsan Çaliş. "Iridoid and Phenylethanoid Glycosides fromPhlomis longifoliavar.longifolia." Natural Product Letters 15, no. 5 (2001): 345–51. http://dx.doi.org/10.1080/10575630108041302.

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37

Ma, Qinge, Yongming Guo, Baomin Luo, et al. "Hepatoprotective phenylethanoid glycosides from Cirsium setosum." Natural Product Research 30, no. 16 (2015): 1824–29. http://dx.doi.org/10.1080/14786419.2015.1084304.

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38

Niu, Chao, Qiang Li, Lan-Ping Yang, et al. "Phenylethanoid glycosides from Callicarpa macrophylla Vahl." Phytochemistry Letters 38 (August 2020): 65–69. http://dx.doi.org/10.1016/j.phytol.2020.05.013.

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39

Zhou, Bing-Nan, Brian D. Bahler, Glenn A. Hofmann, Michael R. Mattern, Randall K. Johnson та David G. I. Kingston. "Phenylethanoid Glycosides fromDigitalispurpureaandPenstemonlinarioideswith PKCα-Inhibitory Activity". Journal of Natural Products 61, № 11 (1998): 1410–12. http://dx.doi.org/10.1021/np980147s.

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40

Chakravarty, Ajit Kumar, Tapas Sarkar, Takahisa Nakane, Nobuo Kawahara, and Kazuo Masuda. "New Phenylethanoid Glycosides from Bacopa monniera." CHEMICAL & PHARMACEUTICAL BULLETIN 50, no. 12 (2002): 1616–18. http://dx.doi.org/10.1248/cpb.50.1616.

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41

Ye, Miao, Yun Zhao, Vanessa L. Norman, et al. "Antibiofilm phenylethanoid glycosides from Penstemon centranthifolius." Phytotherapy Research 24, no. 5 (2009): 778–81. http://dx.doi.org/10.1002/ptr.2992.

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42

Yuan, Jing-Quan, Li Qiu, Lu-Hui Zou, Qian Wei, Jian-Hua Miao, and Xin-Sheng Yao. "Two New Phenylethanoid Glycosides fromCallicarpa longissima." Helvetica Chimica Acta 98, no. 4 (2015): 482–89. http://dx.doi.org/10.1002/hlca.201400206.

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43

Huang, Jin, Dandan Zhao, Chaojing Cui, Jianxiong Hao, Zhentao Zhang, and Limin Guo. "Research Progress and Trends of Phenylethanoid Glycoside Delivery Systems." Foods 11, no. 5 (2022): 769. http://dx.doi.org/10.3390/foods11050769.

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Background: Phenylethanoid glycosides (PhGs) are obtained from a wide range of sources and show strong biological and pharmacological activities, such as antioxidant, antibacterial and neuroprotective effects. However, intestinal malabsorption and the low bioavailability of PhGs seriously affect their application. Delivery systems are an effective method to improve the bioavailability of active substances. Scope and approach: In this article, the biological activities of and delivery systems for PhGs are introduced. The application statuses of delivery systems for echinacoside, acteoside and s

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Wu, Chieh-Ju, Mei-Yin Chien, Nan-Hei Lin, et al. "Echinacoside Isolated from Cistanche tubulosa Putatively Stimulates Growth Hormone Secretion via Activation of the Ghrelin Receptor." Molecules 24, no. 4 (2019): 720. http://dx.doi.org/10.3390/molecules24040720.

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Cistanche species, the ginseng of the desert, has been recorded to possess many biological activities in traditional Chinese pharmacopoeia and has been used as an anti-aging medicine. Three phenylethanoid glycosides—echinacoside, tubuloside A, and acteoside—were detected in the water extract of Cistanche tubulosa (Schenk) R. Wight and the major constituent, echinacoside, was further purified. Echinacoside of a concentration higher than 10−6 M displayed significant activity to stimulate growth hormone secretion of rat pituitary cells. Similar to growth hormone-releasing hormone-6, a synthetic a

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Kırmızıbekmez, Hasan, Norbert Kúsz, Nursenem Karaca, Fatih Demirci, and Judit Hohmann. "Secondary Metabolites from the Leaves of Digitalis viridiflora." Natural Product Communications 12, no. 1 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200117.

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A new phenylethanoid glycoside, named digiviridifloroside (1), was isolated from the leaves of Digitalis viridiflora Lindley along with a known phenylethanoid glycoside calceolarioside A (2), two flavonoid glycosides, scutellarein 7- O-β-D-glucopyranoside (3) and hispidulin 7- O-β-D-glucopyranoside (4), two cleroindicins, cleroindicins B (5) and F (6), a nucleoside, adenosine (7), as well as a mixture of β-glucopyranosyl-(1→6)-4- O-caffeoyl-α/β -glucopyranose and 3,4-dihydroxyphenylethanol. The structure of the new compound was established as 3,4-dihydroxy-β-phenylethoxy-6- O-( E)-feruloyl-glu

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Petreska, Jasmina, Gjose Stefkov, Svetlana Kulevanova, Kalina Alipieva, Vassya Bankova, and Marina Stefova. "Phenolic Compounds of Mountain Tea from the Balkans: LC/DAD/ESI/MSn Profile and Content." Natural Product Communications 6, no. 1 (2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600107.

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Twenty-one samples of Sideritis species ( S. scardica, S. raeseri, S. taurica, S. syriaca and S. perfoliata) from various locations on the Balkan Peninsula were evaluated for their chemical constituents. Chemical analyses were focused on secondary metabolites, particularly phenolic compounds, which have several roles in the plant physiological processes and have demonstrated significant health beneficial effects. The occurrence of hydroxycinnamic acids, phenylethanoid glycosides and flavonoids has been investigated in taxonomically related taxa of the genus Sideritis. A systematic method for p

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Shao, Si-Yuan, Zi-Ming Feng, Ya-Nan Yang, Jian-Shuang Jiang, and Pei-Cheng Zhang. "Forsythenethosides A and B: two new phenylethanoid glycosides with a 15-membered ring from Forsythia suspensa." Organic & Biomolecular Chemistry 15, no. 33 (2017): 7034–39. http://dx.doi.org/10.1039/c7ob01811h.

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Tanaka, Tomonori, Tsuyoshi Ikeda, Miho Kaku, et al. "A New Lignan Glycoside and Phenylethanoid Glycosides from Strobilanthes cusia BREMEK." CHEMICAL & PHARMACEUTICAL BULLETIN 52, no. 10 (2004): 1242–45. http://dx.doi.org/10.1248/cpb.52.1242.

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de Santana Julião, Lisieux, Anna Lisa Piccinelli, Stefania Marzocco, et al. "Phenylethanoid Glycosides fromLantana fucatawithin VitroAnti-inflammatory Activity." Journal of Natural Products 72, no. 8 (2009): 1424–28. http://dx.doi.org/10.1021/np9002383.

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Kaewkongpan, Choosak, Poolsak Sahakitpichan, Somsak Ruchirawat, and Tripetch Kanchanapoom. "Iridoid and phenylethanoid glycosides from Heterophragma sulfureum." Phytochemistry Letters 12 (June 2015): 277–81. http://dx.doi.org/10.1016/j.phytol.2015.04.016.

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