Academic literature on the topic 'Phenytoin Gingival Hyperplasia'

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Journal articles on the topic "Phenytoin Gingival Hyperplasia"

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AlJehani, Yousef A. "Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia." Journal of Contemporary Dental Practice 16, no. 4 (2015): 319–21. http://dx.doi.org/10.5005/jp-journals-10024-1683.

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ABSTRACT Introduction The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient. Materials and methods A 12-year-old male epileptic patient, undergoing PHT therapy, was diagnosed clinically with severe gingival hyperplasia. His treatment consisted meticulous oral care and weekly professional prophylaxis. The patient was advised oral folic acid supplementation (0.5 mg/day) and was also recommended 0.2% chlorhexidine gluconate mouthwash twice daily. Results There was significant reduction in the hyperplastic tissue within 4 weeks of tre
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Sharma, Sanjay, and S. K. Dasroy. "Gingival Hyperplasia Induced by Phenytoin." New England Journal of Medicine 342, no. 5 (2000): 325. http://dx.doi.org/10.1056/nejm200002033420505.

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Saleem, Sheikh, Sawan Verma, Irfan Yousuf, Mushtaq Ahmad Wani, and Ravouf Asmi. "Diphenylhydantoin Induced Severe Gingival Hyperplasia." JMS SKIMS 20, no. 1 (2017): 44–46. http://dx.doi.org/10.33883/jms.v20i1.311.

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Gingival overgrowth (GO) is a side effect, associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressant, and calcium channel blockers. One of the main drugs associated with GO is the antiepileptic, diphenylhydantoin (DPH)/ phenytoin (1), which affects gingival tissues by altering extracellular matrix metabolism. Phenytoin (DPH)-induced gingival overgrowth (PIGO) due to chronic administration remains an unsolved problem especially in cases where this drug is taken without any supervision due usually to poor follow-up. Younger age groups experience more lesions than
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Vahabi, Surena, Bahareh Nazemi salman, and Pouya Pourgolshani. "Effect of Phenytoin and Cyclosporine on IL-17 Production by Gingival Fibroblasts of Adults and Children." Journal of Periodontology & Implant Dentistry 7, no. 1 (2018): 1–6. http://dx.doi.org/10.15171/jpid.2015.001.

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Background and aims. Gingival hyperplasia, a relatively common side effect of antiepileptic and anticonvulsant drugs, occurs in 30‒50% of patients taking phenytoin and 25‒81% of those taking cyclosporine. Gingival hyperplasia due to lack of balance between extracellular synthesis and degradation is associated with increased production of IL-1B, IL-6 and IL-8 by gingival fibroblasts. Tissue level of IL-17 increases in inflammatory conditions. Since the role of IL-17 and patient age in gingival hyperplasia is still unclear, this study aimed to compare the level of IL-17 produced by gingival fibr
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Shaftic, Alison A., Lorie L. Widdup, Marie A. Abate, and Arthur I. Jacknowitz. "Nifedipine-Induced Gingival Hyperplasia." Drug Intelligence & Clinical Pharmacy 20, no. 7-8 (1986): 602–5. http://dx.doi.org/10.1177/106002808602000724.

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Gingival hyperplasia, a condition characterized by increased amounts of gingival connective tissue, has most commonly been observed in patients receiving phenytoin, but has also been noted in patients receiving cyclosporine and, as in this case report, nifedipine. Patients receiving nifedipine should be advised to practice good oral hygiene to lessen the possibility of hyperplasia occurring. If gingival hyperplasia develops in a patient taking nifedipine, the drug should be suspected as being
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Farook, Fathima Fazrina, Mohamed Nuzaim M. Nizam, and Abdulsalam Alshammari. "An Update on the Mechanisms of Phenytoin Induced Gingival Overgrowth." Open Dentistry Journal 13, no. 1 (2019): 430–35. http://dx.doi.org/10.2174/1874210601913010430.

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Background: Phenytoin induced gingival overgrowth, a side effect with multifactorial aetiology, is characterized by an increase in the volume of extracellular tissues, particularly collagenous components, with varying degrees of inflammation. Objective: The aim of this paper is to review the available literature regarding the pathophysiological mechanisms of phenytoin induced gingival overgrowth. Methods: A thorough literature search of the PubMed/ Embase/ Web of science/ Cochrane central database was conducted to identify the mechanisms involved in the process of phenytoin-induced gingival ov
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Lafzi, Ardeshir, Ramin Mostofi Zadeh Farahani, and Mohammad Ali Mohajjel Shoja. "Phenobarbital-induced Gingival Hyperplasia." Journal of Contemporary Dental Practice 8, no. 6 (2007): 50–56. http://dx.doi.org/10.5005/jcdp-8-6-50.

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Abstract Aim The aim of this article is to present a case of a phenobarbital-induced gingival hyperplasia (GH), discuss possible etiological mechanisms of drug-induced GH, and to present a concise review of the literature. Background GH is a well-known complication associated with anticonvulsant phenytoin, antihypertensive calcium channel blockers, and immunosuppressant cyclosporine therapy. Sodium valproate and primidone has very rarely been found to cause GH. Report An extremely rare case of phenobarbital-induced GH in a 28-year-old male patient who had received this drug for three years is
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KASSAI, Yasuhiro, Yuri OKISHIO, Tomonobu KIDA, Shigeyuki EBISU, and Hiroshi OKADA. "Immunopathological studies of phenytoin-induced gingival hyperplasia." Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 27, no. 1 (1985): 197–205. http://dx.doi.org/10.2329/perio.27.197.

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Millichap, J. Gordon. "Folic Acid Supplement Prevents Phenytoin-Induced Gingival Hyperplasia." Pediatric Neurology Briefs 25, no. 5 (2011): 35. http://dx.doi.org/10.15844/pedneurbriefs-25-5-3.

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Butler, Rex T., Kenneth L. Kalkwarf, and Wayne B. Kaldahl. "Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine." Journal of the American Dental Association 114, no. 1 (1987): 56–60. http://dx.doi.org/10.14219/jada.archive.1987.0050.

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Dissertations / Theses on the topic "Phenytoin Gingival Hyperplasia"

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Dahllöf, Göran. "Phenytoin-induced gingival overgrowth in epileptic children a clinical, histological and biochemical study /." Stockholm : [Karolinska Institutet], 1986. http://catalog.hathitrust.org/api/volumes/oclc/13674550.html.

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