Journal articles: 'Phlegmona'

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Trnavec, B., E. Vodrazkova, and A. Cernak. "Orbital phlegmona from upper eyelid chalazion." Bratislava Medical Journal 117, no. 05 (2016): 299. http://dx.doi.org/10.4149/bll_2016_059.

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Perepelitsa, Oleg, and Petr Latyshev. "Safety of airway management during phlegmona of submandibular area." Trends in Anaesthesia and Critical Care 30 (February 2020): e37-e38. http://dx.doi.org/10.1016/j.tacc.2019.12.096.

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Baumgart, Daniel C., Bertram Wiedenmann, and Axel U. Dignass. "Successful Therapy of Refractory Pyoderma Gangrenosum and Periorbital Phlegmona With Tacrolimus (FK506) in Ulcerative Colitis." Inflammatory Bowel Diseases 10, no. 4 (July 2004): 421–24. http://dx.doi.org/10.1097/00054725-200407000-00014.

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Vukovic, Mira, and Mirjana Lapcevic. "The role of pentoxifylline in nitrogen conversion in patients suffering from diabetic phlegmona of the foot." Srpski arhiv za celokupno lekarstvo 134, Suppl. 2 (2006): 119–21. http://dx.doi.org/10.2298/sarh06s2119v.

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INTRODUCTION. It is known that pentoxifylline is the only medicament to date which has been clinically proven to lead to nitrogen conversion in uremic patients. Positive results of application of pentoxifylline in prevention of systemic inflammatory response syndrome have also been published, as well as in prevention and treatment of the acute respiratory distress syndrome. OBJECTIVE. The goal of our study was to investigate the effect of four-day treatment with pentoxifylline in a dose of 300 mg dissolved in 500 ml of normal saline, administered as 20-hour intravenous infusion per day, on the conversion of nitrogen in 11 patients suffering from diabetic phlegmona of the foot, and with pathological values of urea and creatinine. METHOD. All patients had 3 repeated negative blood cultures, and at least one positive out of three wound swabs. Seven patients were insulin independent, and 4 insulin dependent. Before treatment, all patients had pathological findings of white blood cells, in the form of granulocytosis, with appearance of young cells. Patients were prescribed adequate antibiotics according to drug susceptibility test, and glycemia was monitored every 6 hours, with correction of diabetes therapy. Patient?s dressings were changed once a day, while urea and creatinine were checked immediately before the onset of pentoxifylline therapy, as well as after four days of therapy. Statistical analysis was done using the McNemar test for linked sample. RESULTS. The results showed that pathological values of white blood cells persisted in all patients, and after four days of therapy, blood urea restored to normal in 9 patients (Z=-3; p=0.003), and blood creatinine in 10 patients (Z=-3, 162; p=0.002). There was no need to make corrections of diabetes therapy. CONCLUSION. It can be concluded that pentoxifylline can prevent further degradation of nitrogen in patients suffering from phlegmona of the foot, decreasing the catabolic effect of infection, most probably by inhibiting the effect of TNF-alpha, interleukin-1 and interleukin-6, without any significant effect on leukocytosis during four days of treatment.

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Bortnik, P., P. Wieczorek, P. Załęski, P. Kosierkiewicz, A. Siemiątkowski, E. Tryniszewska, and J. Borys. "Odontogenic phlegmon of the mouth floor: a case report." Progress in Health Sciences 6, no. 2 (December 1, 2016): 0. http://dx.doi.org/10.5604/01.3001.0009.5166.

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Odontogenic phlegmon of the mouth floor—Ludwig's angina (phlegmonae fundi cavi oris seu angina Ludovici)—is a rare, life-threatening, local complication in most cases of odontogenic inflammation. This study presents the case of a patient treated in the Department of Maxillofacial and Plastic Surgery of the University Hospital in Białystok due to phlegmon of the mouth floor resulting from odontogenic inflammation with a dynamic course. Quick diagnostics, surgical intervention as well as antibiotic therapy contributed to its efficient and successful treatment.

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Сherniak, L. A. "PHOTODYNAMIC THERAPY IN COMPLEX TREATMENT OF PHLEGMON OF THE MAXILLOFACIAL AREA AND NECK." Journal of the Grodno State Medical University 19, no. 4 (September 12, 2021): 397–403. http://dx.doi.org/10.25298/2221-8785-2021-19-4-397-403.

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Background. The treatment of phlegmon of the maxillofacial area and neck at the present moment remains difficult and insufficiently effective. Aim. To develop a method of using photodynamic therapy (PDT) for the treatment of phlegmon of the maxillofacial area and neck and to evaluate its effectiveness. Material and methods. A total of 92 patients with phlegmons of the maxillofacial area and neck were under observation. They were divided into 3 groups: group 1 – “control group 1” (30 patients) – where traditional treatment was used, group 2 – “control group 2” (30 patients) – in which low-intensity laser radiation was used in addition to topical treatment and group 3 – “experimental” (32 patients) – where PDT was used for topical treatment. Results. The data of clinical, cytological and bacteriological studies show that the local application of PDT has an anti-inflammatory effect and stimulates the reparative processes in the wound, and shortens the treatment period for patients. Conclusion. PDT improves the results of complex treatment of patients with phlegmons of the maxillofacial area and neck. Its application leads to the purification of a purulent wound on the 3rd (3;4) day, allows to apply secondary sutures on the 7th day and to shorten the period of inpatient treatment in comparison with the control groups from 3 to 9 days.

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Shchenin, Andrei V. "Features of oral immunity indicators in patients with phlegmons of the maxillofacial region against the background of insulin-independent diabetes mellitus." Человек и его здоровье 24, no. 1 (June 2021): 10–18. http://dx.doi.org/10.21626/vestnik/2021-1/02.

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Objective: studying the interrelations of the local oral immunity indicators which allow to predict the severity of phlegmons course in patients with maxillofacial region phlegmons against the background of insulin-independent diabetes mellitus. Materials and methods. 44 patients were included in this prospective study. The main group: 19 patients with the maxillofacial region phlegmons and the type 2 diabetes mellitus as a concomitant pathology (PH+DM). The comparison group: 20 patients with the maxillofacial region phlegmons with no diabetes mellitus among the concomitant pathologies (PH). The control group: 5 patients were undergoing routine surgical treatment in the maxillofacial surgery department. The groups were comparable in age, gender, and phlegmon treatment (p > 0.05). Levels of the proinflammatory and anti-inflammatory cytokines, the humoral immunity factors and the microbial adsorption reaction (MAR) index to the oral epithelial cells were determined in the saliva of patients on the 1st and 5th days. The obtained data were statistically processed. Results. On the 1st day of hospital treatment the PH+DM group revealed an increase in interleukin-6, a decrease in interleukin-10 and lactoferrin as compared to the PH and control groups (p < 0.05). On the 5th day of the treatment the interleukin-6 and tumor necrosis factor-α levels did not differ between PH+DM and the control groups (p < 0.05). The interleukin-4 and interleukin-10 levels were lower in the PH+DM and PH groups than in the control group on the 5th day (p < 0.05). The lactoferrin level in the PH+DM group was lower than in the PH and control groups (p < 0.05). The significant negative correlation was found between the MAR index values and SOFA (Sequential organ failure assessment score) points in patients with sepsis, R = -0.9 (p < 0.05). Conclusion. The delayed regression of the saliva inflammation indicators was specific for the PH+DM group patients in comparison with the PH group patients. The MAR index below 10% may be a predictor of unfavorable course of the phlegmon development.

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Joksimović, Vladimir, Nikola Jankulovski, Svetozar Antović, Marija Joksimović, and Ljubinka Mančeva. "The Occurrence of Postoperative Complications in Patients Undergoing Surgery due to Complications from Crohn's Disease: A Case Report." Acta Facultatis Medicae Naissensis 35, no. 1 (March 1, 2018): 73–80. http://dx.doi.org/10.2478/afmnai-2018-0008.

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Summary Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract that can give rise to strictures, inflammatory masses, fistulas, abscesses, hemorrhage, and cancer. This disease commonly affects the small bowel, colon, rectum or anus. Less commonly, it affects the stomach, esophagus and mouth. Often, the disease affects multiple areas of the gastrointestinal tract. The cause of CD is not known and there is no curative treatment. The current medical and surgical treatment is effective in controlling the disease, but even with optimal treatment, recurrences and relapses are frequent. Various risk factors specific for the patients with conditions related to the CD can influence the outcome of the surgical treatment in the postoperative period. Those risk factors can be preoperative laboratory inflammatory markers such as WBC and CRP values, phlegmona of the anterior abdominal wall and preoperative interintestinal abscess, positive resection margins. Here we present a case of a patient who was surgically treated as an emergent case because of the complication due to Crohn's disease. At presentation, the patient had leukocytosis, elevated CRP, anemia, low levels of total proteins, and albumin.

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Schtraube, G. I., Iosif A. Boev, A. P. Godovalov, and G. I. Antakov. "SOME CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF THE MAXILLOFACIAL AREA PHLEGMONS." Russian Journal of Dentistry 21, no. 5 (October 15, 2017): 241–44. http://dx.doi.org/10.18821/1728-2802-2017-21-5-241-244.

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Introduction. It is known that the number of patients with phlegmons does not tend to decrease, which can be due to both disease pathomorphosis and changes in the epidemiological features of this pathology. In addition, a significant contribution to the development of the disease makes the characteristics of the comorbidity background. The aim of the study was to assess the clinical and epidemiological aspects of the morbidity of the Perm city population with the maxillofacial area phlegmons. Materials and methods. A retrospective analysis of 137 case reports ofpatients with facial phlegmon was carried out. Results. It is shown that young and middle-aged patients dominated in the age structure of the disease. Phlegmons often localized in 1-2 spaces. In more than half the cases, the phlegmons was in the submandibular space. Among the etiological factors of the disease, the leading place is occupied by gram-positive cocci and their associations. An essential role of anaerobic microflora in the pathogenesis of phlegmons has been established. Microorganisms of the Enterobacteriaceae family play a significant role in the formation of inter-microbial associations in the development of this pathology. Often phlegmons of the maxillofacial region are found in patients with concomitant somatic pathology. With a comorbid component, more frequent detection of microorganism associations is indicated. In addition, such patients enter the hospital much later. Conclusion. Thus, when assessing clinical and epidemiological data, it is shown that the phlegmons of the maxillofacial region occur, as a rule, in young and middle age, and also in the presence of comorbid pathology. A significant contribution to the development of the disease is made by associations of microorganisms, which may include a change in the severity ofpathogenicity factors.

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Boev, I. A., A. P. Godovalov, G. I. Shtraube, and G. I. Antakov. "Characteristic features of maxillofacial phlegmon morbidity with assessment of efficiency of detoxication therapy." Perm Medical Journal 36, no. 2 (June 23, 2019): 29–35. http://dx.doi.org/10.17816/pmj36229-35.

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Aim. To study the characteristic features of long-term facial phlegmon morbidity in Perm Krai with assessment of the efficiency of infusion therapy using indices of endogenous intoxication expression. Materials and methods. Manifestations of epidemic process of facial phlegmons were studied on the basis of a detailed retrospective analysis of sickness rate among the inhabitants of Perm Krai for the period of 2011–2016. In group 1, all patients besides standard therapy, underwent infusion therapy, and in group 2 – standard therapy alone. Prior to and after the therapy, peripheral blood cellular composition was assessed, and leukocytic indices of intoxication were calculated. Results. A long-term dynamics of facial phlegmon morbidity was established to show the irregularity of process expression according to years. Growth of the quantity of patients is provided by increase in the number of cases with complicated forms. Besides, males play a significant role in formation of sickness rate: the chances for the development of phlegmon among them are 1.49 times higher than in females. In the age structure of morbidity, prevail persons aged 21–30 and 31–50. A half of patients have endogenous intoxication. The course of infusion therapy essentially reduces the expression of endogenous intoxication. Conclusions. There is observed a tendency to growth of facial phlegmon morbidity that is probably connected with changes in etiological structure of pathogenic agents as well as with formation of pathosymbiosis of some opportunistic pathogenic microorganisms. As a rule, phlegmon is being developed against the background of endogenous intoxication, conditioned by both microbial metabolites and tissue destruction products. The efficiency of correction of endogenous intoxication using infusion therapy is shown.

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Beschastnov, Vladimir Victorovich, Michail Alexandrovich Sizov, Maxim Vladimirovich Bagryantsev, Yury Vladimirovich Tretyakov, and Maxim Georgievich Ryabkov. "Сomprehensive treatment of the complicated phlegmona of the top limb on the background of sugar diabetes under hiv coinfection and virus hepatitis." Vestnik of Experimental and Clinical Surgery 11, no. 2 (June 30, 2018): 105–9. http://dx.doi.org/10.18499/2070-478x-2018-11-2-105-109.

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Despite the active development and introduction into clinical practice of new groups of antibacterial drugs, the basis for the treatment of purulent-septic diseases of soft tissues is the opening and surgical treatment of a purulent focus. When we analyzing the literature data on the treatment of purulent soft tissue diseases, the following factors can be identified that determine the progression of the purulent-inflammatory process even with an adequately uncovered purulent focus: the presence of common co-morbid diseases that reduce the body's resistance (infectious diseases and metabolic disorders) and attachment to the pathological process multidrug-resistant virulent hospital flora [1, 2]. Progression of the purulent-necrotic process takes place along anatomically determined paths of pus spread, and therefore the absolute necessity of firm knowledge of the topographic anatomy of the human body is obvious. Perhaps the most complete and thorough description of the clinical picture and methods of surgical treatment of phlegmon of the upper limb and thorax, based on anatomical principles, is given in the classic work of V.F. Voino-Yasenetsky [3], since the first publication of which it has been almost a century. Currently, due to the prevalence of antibiotic resistance even of "wild" microorganisms, the prevalence among infectious diseases affecting the immune status of the organism (hepatitis, tuberculosis, HIV), as well as the pandemic of diabetes, the urgency of surgical treatment of common purulent processes in the region upper extremity and thorax again increased. We present the clinical case of progression of the purulent process on the left upper limb from the lower third of the arm in the distal direction to the Pirogov-Paron space and in the proximal direction to the submentoral and pre-lobular cell spaces.

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Kurbonov, Yokubjon Khamdamovich, Shukhrat Abdujalilovich Boymuradov, and Jamolbek Abdukakharovich Djuraev. "Purulent-Necrotic Diseases Of The Face: Aspects Of Diagnostics And Treatment." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 01 (January 15, 2021): 24–30. http://dx.doi.org/10.37547/tajmspr/volume03issue01-05.

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The problem of treatment of pyoinflammatory diseases (PID) of the face and neck is relevant for both dentists of polyclinics and maxillofacial surgeons in hospitals. About 50% of those in maxillofacial hospitals, and about 20% of those who seek help from a dentist and a surgeon of polyclinics, are patients with inflammatory diseases of the maxillofacial region (MFO), among them - 60-80% of patients with abscesses and phlegmons, the frequency of which has increased by 1.5–2.0 times over the past decade. There has been a steady growth of atypical and severely flowing progressive phlegmon, spreading simultaneously in several cellular spaces, with the development of such formidable complications as sepsis, contact mediastinitis, and thrombosis of the cavernous sinus of the dura mater. Low-symptom “erased” forms of phlegmon are found among 13.4–22% of patients, are characterized by a long course and are difficult to diagnose, which contributes to late hospitalization and untimely treatment started. Microbial etiology of HVZ CLO is due to the localization of the primary process (connection with the oral cavity, teeth).

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Stepanov, D. A., and Stanislav Y. Maksyukov. "TREATMENT TACTICS FOR COMPARTMENT SYNDROME IN PATIENTS WITH COMBINED PHLEGMONS OF SUBMANDIBULAR AND SUBMENTAL SPACE." Russian Journal of Dentistry 22, no. 3 (June 15, 2018): 146–49. http://dx.doi.org/10.18821/1728-2802-2018-22-3-146-149.

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Case monitoring to reveal the clinical pattern of compartment syndrome in patients suffering from sub-mandibular and submental space phlegmons was carried out. Two trend groups were formed: the primary group (33 patients) where compartment syndrome was diagnosed and treated according to an original method (RF Patent No. 2612830) including ultrasound wound treatment and ozone therapy, and the control group (32 patients) treated using established methods. In the control group, steady-state character of postoperative status was observed, while the primary group demonstrated regressive character. Good results in 93,9% and satisfactory results in 6,1% of the patients allow to recommend the developed patient surveillance tactics for phlegmon cases in clinical practice.

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Shaprynskyy, V. O., V. F. Kryvetskyy, V. H. Suleymanova, B. O. Mityuk, and T. A. Khmelevska. "Systemic inflammatory response indicators in patients with neck phlegmons." Modern medical technologies 41 part 3, no. 2 (2019): 25–28. http://dx.doi.org/10.34287/mmt.2(41).2019.35.

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Purpose of the study. To study systemic inflammatory response indexes in patients with neck phlegmons. Materials and methods. All patients were divided on two groups. In general group (84 people) treatment included vulnerosorption with modern composition. The control group consisted of 57 patients taking hydrophilic ointments. To investigate the severity of endotoxicosis, Morozova’s scales and predictors of leukocyte index of intoxication, the index of the ratio of neutrophils and lymphocytes, lymphocytic-granulocyte index, were used.Results. The most frequent complications included sepsis (64,5%), toxic myocarditis (60%), toxic nephritis (68%) and mediastinitis (48,2%). Morozov's index of 113 (80%) patients was 41,5 ± 5 (severe endogenous intoxication); among the last 28 (20%) it showed 29,7 ± 2,6 (the average degree of intoxication). Changes of leukocyte index of intoxication, the index of the ratio of neutrophils and lymphocytes, lymphocytic-granulocyte index in patients treated with sorption composition showed more positive dynamics compared with the control group. The mortality in general group was 4,8% vs 14% in the control group.Conclusions.Deep neck phlegmons are characterized by severe endotoxicosis and lead to sepsis in 64,5% and mediastinitis in 48,2% cases. Morozova’s scales are useful to study the level of endotoxicosis in patients with neck phlegmons. Investigated sorption composition is more effective than a hydrophilic ointment, what confirms the dynamics of leukocyte index of intoxication, the index of the ratio of neutrophils and lymphocytes, ymphocytic-granulocyte index.Keywords: neck phlegmon, endogenous intoxication, leukogram, mediastinitis,vulnerosorption.

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Sidoryako, A. V., V. A. Malanchuk, and N. G. Barannik. "The platelet-rich plasma influence on the inflammatory process in proliferation stage." Modern medical technologies 40, no. 1 (February 19, 2019): 48–51. http://dx.doi.org/10.34287/mmt.1(40).2019.8.

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One of the known methods of treatment is biomesotherapy, in which the patient’s own biomaterials are used for injection. It ensures complete biocompatibility and practically eliminates the possibility of beginning the allergic reactions. One of the options for mesotherapy is the using of Plasmolifting TM (plasmolifting) – commercially patented title of PRP-therapy (Platelet Rich Plasma), which involves the using of an injection form of platelet-rich plasma.Purpose of the study. Increase the efficiency treatment phlegmon of the maxillofacial area and neck with the help of impact of autoplasma rich in platelets on the proliferative phase.Materials and methods. We carried out the diagnosis and complex treatment of 80 patients with odontogenic phlegmons who were hospitalized in the Department ofMaxillofacial Department. surgical and therapeutic dentistry State Institution «Zaporizhia Medical Academy of post-graduate education Ministry of Health of Ukraine». The patients were divided into 2 groups: 1st group – 25 patients, their treatment was carried out by the traditional method and 2nd group – 55 patients among whom platelet-rich plasma (PRP) was added to the treatment at the repair stage.Conclusions. Treatment in this way accelerated the course of the healing process due to the additional reparative and proliferative effects of such therapy. Keywords: maxillofacial area, phlegmon, autoplasma, platelets.

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Malanchuk, V. A., and A. V. Sidoryako. "Evaluation of dynamics of inflammatory process in patients with flegmones of shell-facial plants." Modern medical technologies 41 part 1, no. 2 (April 6, 2019): 25–28. http://dx.doi.org/10.34287/mmt.2(41).2019.5.

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Modern and glance at the methods of diagnosis and treatment of patients with odontogenic inflammatory diseases of the maxillofacial area and neck was and remains one of the pressing problems that are frequent complications that lead to disorders in the tooth-jaw system, and can be a direct life-threatening ill. Purpose of the study. To increase the effectiveness of treatment of phlegmon of maxillofacial area and neck due to the active evaluation of the dynamics of the inflammatory process comparing a specific patient with standard indicatorschanges in the limits of edema of infiltration. Materials and methods. We carried out diagnostics and complex treatment of 120 patients with odontogenic phlegmons, who were in hospital treatment. The patients were divided into 2 groups: group I – 60 patients, treatment of which was carried out by the traditional method. Group II – 60 patients, modern treatment methods regional administration of attibiotics, vacuum drainage of purulent wound and plasmolifting at the stage of reparation, were added to their standard therapy. Conclusions: The proposed method is simple, reliable and does not require expensive equipment and makes it possible to predict the development of the disease only by clinical measurements of the volume of inflammation. Keywords: maxillofacial area, phlegmon, autoplasma, platelets, evaluation of the inflammatory process dynamics.

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Steblovskyi, D. V., V. V. Bondarenko, O. S. Ivanytska, V. M. Skrypnyk, and I. O. Ivanytskyi. "CLINICAL ASSESSMENT OF THE EFFECTIVENESS APPLICATION "BIOCERULIN" IN THE COMPLEX TREATMENT OF THE PATIENTS WITH ONTOGENIC FLAGMONS OF THE MAXILLOFACIAL AREA." Ukrainian Dental Almanac, no. 4 (December 26, 2019): 29–32. http://dx.doi.org/10.31718/2409-0255.4.2019.05.

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Treatment of odontogenic phlegmon of the maxillofacial region remains an urgent problem of surgical dentistry due to the steady increase in their frequency, tendency to generalize the process and adverse effects. In this regard, there is a constant search for ways to improve the effectiveness of treatment of patients with odontogenic phlegmons of maxillofacial region. New technologies of drug treatment of this pathology are developed and put into practice. In recent years the attention of researchers in various conditions accompanied by the development of oxidative stress began to attract drugs that have antioxidant action, as it became known that the excess of reactive oxygen species in the regenerating wounds in the hearth of purulent inflammation affects the course of the course, wound healing. Interest in the treatment of various pathological conditions of the body is caused by the domestic antioxidant multifunctional enzyme "Bioceruline" which is composed of copper. In this regard, the purpose of our study was to evaluate the effectiveness of the use of "Biocerulin" in the complex treatment of patients with odontogenic phlegmon of maxillofacial region. The object of the clinical study was 45 patients with odontogenic phlegmons of the maxillofacial region from 18 to 55 years old, who were treated in the maxillofacial department of PU "Poltava M.V. Sklifosovskyi regional clinical hospital PRC». All patients were without somatic pathology in compensated clinical condition. Immediately after hospitalization, patients underwent an emergency opening of purulent lesion, revision and adequate drainage of the affected cellular spaces, removal of the "causal" tooth. The extent of surgery and the choice of optimal access depended on the location and prevalence of phlegmon. Depending on the treatment, patients were divided into comparison groups (22 patients) and the main group (23 patients). The traditional therapy was used in the comparison group. "Biocerulin"was prescribed for the patients of the main group in addition to the traditional therapy. Analysis of obtained data in the treatment of patients with phlegmon revealed that both groups of patients had clear differences in the clinical course of purulent-inflammatory process. On the 2nd day after the opening of the phlegmon theweakness, headache, and sleep disorders were noted in the most of the patients of the comparison group who received traditional therapy. Pain with varying degrees of intensity was present in all patients. Improvement of the general condition of patients of this group was noted not earlier than 3-5 days after surgery. The improvement of the general condition and reduction of pain, normalization or decrease in body temperature, the beginning of restoration of function of the jaw apparatuswere notedin patients of the main group on the background of the introduction of "Bioceruline" already on the 2-3rd day after surgery. Thus, on the basis of the conducted researches it is possible to conclude that the basic (traditional) conservative therapeutic measures used for patients of the comparison group are not effective enough for the relief of the local and general inflammatory process, which caused the prolonged nature of organ-specific and functional rehabilitation of patients as a whole. The use of "Bioceruline" in complex therapy of patients with odontogenicphlegmons of the maxillofacial regionprovides rapid and intensive recovery of the general condition of patients and accelerates reparative processes in the wound and shortens the treatment time via 1.4 bed-days.

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Paramonova, O. A., Ju P. Savchenko, T. V. Gerbova, and A. G. Uvarova. "MODERN TECHNIQUES FOR FACE AND NECK PHLEGMONS TREATMENT." Kuban Scientific Medical Bulletin 25, no. 5 (October 20, 2018): 58–64. http://dx.doi.org/10.25207/1608-6228-2018-25-5-58-64.

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Aim. In the course of this study we carried out the analysis of clinical course features and assessment of microbiological structure of the wound surface in patients with face and neck phlegmons. The etiologic cause of the disease may be hemolytic streptococcus, different types of staphylococcus, mixed flora and anaerobic bacteria.Materials and methods. All patients required urgent surgical intervention: wide opening, drainage of cellular spaces with the subsequent irrigation with antiseptic solutions with the application of a combination of wound coverings "Aquacel Ag + Hydrofiber dressing", "Aquacel Ag Foam Hydrofiber dressing" and "Granuflex" (ConvaTec, the USA) with proper antibacterial therapy.Results. Comparison of clinical observations (favorable course of inflammatory process) and obtained microbiological assessment (quicker decrease of microbial content in the wound) confirms validity, high efficiency of wound covering application and clear advantage in comparison with traditional gauze bandages.Conclusion. The analysis of the causes of phlegmon on the face and neck over the past 5 years has shown a significant increase in the number of patients with traumatic, tonsilogenous and odontogenic phlegmons of the face and neck. The modern high-efficient method of local treatment with the use of wound coverings combinations makes it possible to suppress the purulent-inflammatory process at the early stage, to put the secondary stitches and shorten the period of treatment of patients.

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Akopov, A. L., V. I. Egorov, I. V. Deinega, and P. M. Ionov. "VIDEO-ASSISTED THORACIC SURGERY USING LOCAL ANESTHESIA IN LUNG ABSCESSES AND PYOPNEUMOTHORAX." Grekov's Bulletin of Surgery 174, no. 3 (June 28, 2015): 54–58. http://dx.doi.org/10.24884/0042-4625-2015-174-3-54-58.

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The article presents the results of 42 video-abscessoscopies (VAS) in acute and gangrenous lung abscess and 32 video-thoracoscopies (VTS) in pyopneumothorax, which were performed using local anesthesia and sedation. There were several indication to operation: sanation of cavities, removal of necrotic sequestration and fibrin, decollement, biopsy. Perioperative complications developed after 11 surgeries (13%): emphysema of soft tissues of pectoral cells (5), phlegmon of the thorax (3), bronchial hemorrhage (2), pneumothorax (1). One of the patients died, because of progressing of main disease. VAS and VTS were carried out in 5-8 days after cavity drainage of abscess or pleural cavity in 50 patients. In other 15 cases operations were performed directly before drainage. The bronchial hemorrhage and phlegmons of the thorax were noted in patients of second group. The patients had good tolerance of VAS and VTS operations fulfilled using local anesthesia and sedation. They are safe in case that operation follows drainage of abscess or pleural cavity after decrease of inflammatory processes.

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Prokopiv, O. V., and N. M. Prykuda. "Clinical characteristics of bacterial complications of chickenpox in children." Likarska sprava, no. 1-2 (March 26, 2019): 121–25. http://dx.doi.org/10.31640/jvd.1-2.2019(18).

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The article presents data on the frequency of development and clinical course of bacterial complications of chickenpox in children aged from 2 months to 18 years, who were treated at inpatient department of Infectious Diseases Communal Clinical Hospital in Lviv and surgical department of Communal Municipal Children’s Clinical Hospital in 2000–2016. Bacterial complications were diagnosed in 136 patients (27.2 % out of total number of hospitalized children with chickenpox). Among the complications of chickenpox – lesions of the skin, underlying soft tissues and mucous membranes dominated (43.4 %): surface (pyoderma, erysipelas, conjunctivitis, blepharitis, gingival stomatitis), deep circumscribed (furuncle, abscess), as well as deep non-circumscribed (phlegmons) lesions of various body regions. Particularly severe flow was characterized by phlegmon, which developed in 18.4 % of children, 68% of them with mild forms of chickenpox. Most frequently, phlegmons were diagnosed in children under age 4 years. The first clinical symptoms (swelling and hyperemia with distinct margins, acute tenderness on palpation) appeared on the 3rd–10th day of the disease. Complication of respiratory organs – pneumonia, was diagnosed in 30.1 % of patients. The development of pneumonia was primarily observed in severe forms of chickenpox. Pneumonia, as a rule, developed on the 4th–10th day of the disease and was accompanied by intensification of the signs of intoxication syndrome, appearance of respiratory failure manifestations, cough. Other bacterial complications of chickenpox were also observed in patients: purulent otitis (7.4 % of patients), phlegmonous appendicitis (5.1 %), lacunar tonsillitis (4.4 %), pyelonephritis (3.7 %) cervical lymphadenitis (2.2 %), erosive gastroduodenitis (1.5 %), purulent meningitis (1.5 %), and osteomyelitis (0.7 %). On bacteriological examination of the content, obtained in surgical interventions from the lesion regions in 26 (19.1 %) children, pathogenic and conditionally pathogenic bacteria were isolated. Dominant etiological agents were S. pyogenes та S. aureus.

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Page, C., J. Peltier, C. Medard, Z. Celebi, J. L. Schmit, and V. Strunski. "Phlegmons péritonsillaires." Annales d'Otolaryngologie et de Chirurgie Cervico-faciale 124, no. 1 (March 2007): 9–15. http://dx.doi.org/10.1016/j.aorl.2006.08.001.

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Schwalfenberg, Nico, and Martin Richter. "Indikationen und Grenzen der konservativen Therapie bei Infektionen an der Hand." Handchirurgie · Mikrochirurgie · Plastische Chirurgie 53, no. 03 (June 2021): 231–36. http://dx.doi.org/10.1055/a-1386-4485.

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ZusammenfassungDie Behandlung von Infektionen der Hand ist ein wichtiger Bestandteil des handchirurgischen Alltags. Trotz der Entwicklung verschiedener Antibiotikapräparate bleibt die Operation ein wichtiger Teil der Therapie. Jedoch kann in ausgewählten Fällen eine konservative Therapie indiziert sein, solange eine konsequente Kontrolle gewährleistet ist. Zielführend ist eine sorgfältige Untersuchung und für die Kalkulation des Erregerspektrums eine genaue Anamnese inkl. Beruf, Hobby, Mensch-Tierkontakt, Auslandsaufenthalt und Nebenerkrankungen. Neben der Wahl des geeigneten Antibiotikums sind eine zeitlich limitierte Immobilisation, körperliche Schonung, Verbandanlage und eine Schmerztherapie wichtige Bestandteile der konservativen Therapie. Für die Therapieentscheidung ist die Art der Infektion und die Beachtung der Vorerkrankungen des Patienten wichtig, da bei Immunsuppression mit einer erhöhten Gefahr für Komplikationen, Mischinfektionen und atypischen Erregern gerechnet werden muss. Klassische Indikationen für eine konservative Therapie stellen das Erysipel, die lokale begrenzte Phlegmone mit Lymphangitis, Frühstadien des Panaritiums und der Paronychie dar. Weitere seltenere Indikation sind u. a. Schweinerotlauf, digitale Herpesinfektion und Pilzinfektionen. Nicht geeignet sind in der Regel eine Symptomdauer über 2 Tage, Abszesse, ausgedehnte Phlegmonen (v. a. der Beugesehnenscheide), nekrotisierende Fasziitiden und Gelenkempyeme.

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Sostre, Cesar F., James G. Flournoy, James G. Bova, Harvey M. Goldstein, and Steven Schenker. "Pancreatic phlegmon." Digestive Diseases and Sciences 30, no. 10 (October 1985): 918–27. http://dx.doi.org/10.1007/bf01308290.

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Akramov, E. Kh, A. A. Beysembaev, V. Kh Gabitov, S. K. Sulaymankulova, Omurbek uulu Ulukmyrza, and A. A. Khalmurzin. "MODIFIED METHOD FOR PURULONECROTIC FOOT FLEGMON TREATMENT." Ulyanovsk Medico-biological Journal, no. 2 (July 15, 2020): 80–89. http://dx.doi.org/10.34014/2227-1848-2020-2-80-89.

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Every 30 seconds somewhere in the world there occurs a lower limb amputation in a patient with foot phlegmon. Antibacterial agents are the basis of systemic pharmacotherapy of surgical infections. However, such treatment is rather difficult as it is associated with the loss of antibiotic sensitivity. The purpose of the study is to determine the antibacterial effects of innovative hydrogen peroxide and nanosilver composition combined with chitosan lymphostimulation in foot phlegmon treatment for limb salvage. Materials and Methods. The work is based on the analysis of 46 patients’ treatment outcomes. All the patients suffered from purulent-necrotic foot phlegmons and were treated at the Scientific Center for Reconstructive Surgery, the Ministry of Health of the Kyrgyz Republic and Chuy Regional Combined Hospital. The patients were divided into 2 groups: control group (n=22) – conventional treatments, and active treatment group (n=24) – additional administration of bactericidal-lymphotropic cocktail. The groups were comparable in sex, age, and soft tissue involvement. Results. In patients of active treatment group wound cleansing from wound detritus was observed in 5 days, while in patients undergoing conventional treatment it was detected only in 9 days. In the active treatment group, the granulation time was 1.8 times faster, and the normalization of the leukocyte intoxication index was 2.5 times earlier. The dynamics of the level of medium-weight molecules indicated that lymphostimulation accelerated the interstitium detoxification process in the affected limb by 3 times. Conclusion. The proposed modified method for foot phlegmon treatment with bactericidal-lymphostimulating technologies accelerates tissue regeneration and contributes to limb salvage. Keywords: foot phlegmon, hydrogen peroxide, nanosilver, chitosan. Каждые 30 с в мире пациенту с флегмоной стопы производится ампутация нижней конечности. Основу системной фармакотерапии хирургических инфекций составляют антибактериальные средства, но лечение представляет существенные трудности, связанные с потерей чувствительности к антибиотикам. Цель исследования. Определить эффективность применения инновационной антибактериальной композиции перекиси водорода с наносеребром в комплексе с лимфостимуляцией хитозаном при лечении флегмон стопы в целях сохранения конечности. Материалы и методы. Работа основана на анализе результатов лечения 46 больных с гнойно-некротическими флегмонами стопы, находившихся на лечении в Научном центре реконструктивно-восстановительной хирургии МЗ КР и Чуйской областной объединенной больнице. Все больные, разделенные на 2 группы (контрольная (n=22) – традиционное лечение; основная (n=24) – дополнительное применение бактерицидно-лимфотропного коктейля), были сопоставимы по характеру поражения мягких тканей, полу и возрасту. Результаты. Очищение ран от раневого детрита в основной группе наступало через 5 сут, тогда как при традиционном лечении – только через 9 дней. Появление грануляций в основной группе происходило в 1,8 раза быстрее, нормализация лейкоцитарного индекса интоксикации – в 2,5 раза раньше. Динамика уровня молекул средней массы свидетельствовала о том, что лимфостимуляция ускоряет процесс детоксикации интерстиция региона пораженной конечности в 3 раза. Выводы. Применение предложенного модифицированного способа при лечении флегмон стопы с использованием бактерицидно-лимфостимулирующих технологий ускоряет регенерацию региона и создает условия для сохранения конечности. Ключевые слова: флегмона стопы, перекись водорода, наносеребро, хитозан.

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Lichman, V. O., K. P. Lokes, D. S. Avetikov, M. G. Skikevich, V. V. Bondarenko, and R. A. Prykhidko. "THE APPLICATION OF PLACENTA CRYOEXTRACT IN COMPLEX TREATMENT OF PATIENTS WITH PHLEGMONS OF MAXILLOFACIAL LOCALIZATION." Ukrainian Dental Almanac, no. 2 (June 26, 2020): 58–62. http://dx.doi.org/10.31718/2409-0255.2.2020.09.

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Today the problem of pathogenesis and rational treatment of purulent-inflammatory odontogenic diseases of the maxillofacial area is quite relevant in the field of medical and SOCIAL problems. In recent years, the number of patients with odontogenic inflammatory does not catch an illness, while the number of complications increases. In case of the development of purulent inflammation the complex of interrelated morphological, biochemical, immunological and other changes is observded. The basis in the complex treatment of phlegmon of the maxillofacial area and neck of any localization is active surgical treatment. General therapy for odontogenic inflammatory diseases of the maxillofacial area primarily provides control of infection and intoxication, aimed at normalization of the impaired functions of organs and systems. The purpose of this research was to increase the effectiveness of comprehensive treatment of patients with odontogenic phlegmon of the maxillofacial localization by the use of cryopreserved placental cells. In most cases, the cause of inflammatory processes of maxillofacial localization was untreated periodontal teeth, retained teeth and negligent behavior of patients. That is why the majority of authors believe that the "cause" tooth should be urgently removed, but the solution depends on the individual features of the patient and in some cases may be postponed until the relief of the inflammatory process [3,4]. The combination of local and general factors is necessary to avoid further development of abscesses and phlegmons of the maxillofacial area and neck. The local factors are aerobic and anaerobic infection (staphylococcus, streptococcus, enterococcus, diplococcus, intestinal, gram-positive and gram-negative rods, but less often - mycoplasmas, the simplest of the family Trichomonas, spirochetes, and fungi of the genus Candida). The concentration of causal microflora, general and local nonspecific and specific protective factors of the body, the state of various organs and systems of the body, as well as anatomical and topographic features of the tissues of the maxillofacial area play a significant role in the development and course of purulent-inflammatory processes of the head and neck. All of the above determines the nature of the inflammatory reaction: normergic, hyperergic, hypoergic, anergic. Currently, placental cryoextract preparations are widely used in various fields of medicine, in particular, in urology, gynecology and general surgery. So, maxillofacial surgeons can be interested in their use in the treatment of patients with inflammatory purulent diseases of the maxillofacial localization. That is why carrying out a detailed analysis of native and foreign literature, we have concluded that it is necessary to continue study and scientifically substantiate the issue of optimizing conservative treatment of patients with odontogenic phlegmons with the use of biologically active substances. In further studies it is planned to investigate the impact on the mechanism of purulent wound healing by cryopreserved placenta and to create a morphological and biochemical evidence base for the effectiveness of the proposed treatment.

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Shaprinskiy, V. О., V. F. Kryvetskyi, V. G. Suleimanova, B. O. Mitiuk, and V. Iu Dombrovskyi. "Features of adequate intubating security in patients with odontogenic and tonsilogenic neck phlegmons." Reports of Vinnytsia National Medical University 22, no. 3 (September 28, 2018): 525–28. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(3)-27.

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Recently, a tracheostomy was considered the method of choice for provide ventilating of patients with deep neck phlegmons, but current trends recognize that tracheal intubation with bronchoscope is the most rational way of adequate breathing security in such patients. Objective - to investigate the peculiarities of features of adequate intu bating security in patients with odontogenic and tonsilogenic neck phlegmons. 70 patients with deep neck phlegmons of odontogenic 4(7 (67%)) and tonsilogenic origin - (23 (33%)) have been investigated. 47 (67%) suffered from descending mediastinitis. Tracheal intubation was performed using orotracheal laryngoscope, bronchoscope or through tracheostomy. 33 (47.1%) patients underwent orotra cheal intubation with a bronchoscope, 34 (48.6%) with a laryngoscope, and only in three cases (4.3%) tracheostomy was used. Bronchoscopic intubation was performed in 57.4% of patients with odontogenic phlegmons, and only in 26.1% cases of oropharyngeal spaces suppuration. The percentage of tracheostomies was the same in two groups of patients and showed 4.3%. Mortality rate was 12.9%. Thus, 57.4% of patients with odontogenic neck phlegmons need for bronchoscopic tracheal intubation, a tracheostomy is used extremely rarely (4.3%). Intubation with laryngoscope is possible in 70% of patients with tonsilogenic suppuration. Comparison of tracheal intubation in patients with deep neck phlegmons with and without descending mediastinitis is prospects for further research.

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Chekhodaridi, F. N., Ch R. Persaev, M. S. Gugkaeva, and R. Kh Fidarov. "ETIOPATHOGENETIC THERAPY OF INTERDIGITAL FIBER PHLEGMONE AND PHLEGMONE CORONAE IN COWS." Veterinarny Vrach 3 (2019): 29–34. http://dx.doi.org/10.33632/1998-698x.2019-3-29-34.

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Boev, I. A. "PURULENT INFECTIONS OF THE MAXILLO-FACIAL REGION AMONG HIV INFECTED PATIENTS." HIV Infection and Immunosuppressive Disorders 11, no. 3 (September 14, 2019): 71–74. http://dx.doi.org/10.22328/2077-9828-2019-11-3-71-74.

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The study of the manifestations of the epidemic process of facial phlegmons was carried out on the basis of a detailed retrospective analysis of the incidence rate of the inhabitants of the Perm region for the period from 2011 to 2016. Separately, the incidence of phlegmons among HIV-infected patients was taken into account. As a result of the research, it has been shown that there is a tendency of an increase in the incidence of phlegmons of the face in the general population and a slight decrease among HIV-infected people. The bulk of the cases are people of young and middle age. In HIV-infected patients, facial phlegmons is 8,9 times more common than in the general population, which must be taken into account when providing medical care, especially surgical.

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Sokolow, C. "Les phlegmons à bascule." Annales de Chirurgie de la Main et du Membre Supérieur 14, no. 1 (January 1995): 38–42. http://dx.doi.org/10.1016/s0753-9053(05)80533-2.

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Sokolow, C., N. Dabos, J. P. Lemerle, and R. Vilain. "Phlegmons des gaines digitales." Annales de Chirurgie de la Main 6, no. 3 (January 1987): 181–88. http://dx.doi.org/10.1016/s0753-9053(87)80056-x.

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Belyaev, P. V., E. I. Shtatko, and A. A. Viltsanyuk. "Clinical and laboratory characteristics of the postoperative period in patients with maxillofacial phlegmon." Reports of Vinnytsia National Medical University 22, no. 4 (December 28, 2018): 634–39. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(4)-10.

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The problem of treatment of purulent-inflammatory diseases of the maxillofacial area remains one of the most pressing problems of modern dentistry. The aim of the work is to conduct a clinical and laboratory analysis of the postoperative period in patients operated on for odontogenic phlegmon of the maxillofacial area. 39 patients with odontogenic phlegmons of the maxillofacial area were examined. All patients before surgery, in the postoperative period for 3, 5, 7, 10 days and before discharge, conducted laboratory tests with the definition of a general analysis of blood and urine, the total amount of protein, sugar, urea and creatinine. Serum C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-a) were determined by ELISA with the definition of IMMUNOTECH kits (France) and IMTEK kits (Russia). Endogenous intoxication was determined by the level of molecules of average weight in the blood, leukocyte index and hematological index of intoxication. The obtained data were processed statistically and compared at different periods of observation. During hospitalization in all patients, inflammatory process, severe endogenous intoxication, and systemic inflammatory response syndrome were expressed. In the postoperative period, patients significantly (p<0.05) reduced the total amount of blood protein, erythrocytes, hemoglobin, which a day before discharge were significantly lower (p<0.05) compared with the time of hospitalization. The number of leukocytes, the level of urea and creatinine also decreased before discharge, their indicator was at the level of the upper limit of normal. Up to 5 days after surgery, an elevated level of average weight molecules was established with a gradual reliable (p<0.05) decrease of this indicator to the upper limit of normal before discharge. Up to 5 days after surgery, an elevated level of average weight molecules has been established with a gradual reliable (p<0.05) decrease of this indicator to the upper limit of normal before discharge. In the first 5 days after the start of treatment, there was a significant (p<0.05) increase in the level of CRP¸ TNF-α and IL-6, whose level was normalized before discharge. Clinical and laboratory characteristics of the postoperative period in patients operated on for phlegmon of the maxillofacial region indicates that the severity of the course is due to the development of the systemic inflammatory response syndrome and endogenous intoxication.

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Akayzin, E. S., and A. E. Akayzina. "Indicators of volatile fatty acids for differential diagnostics of nfected of pancreatic necrosis complicated by retroperitoneal phlegmon." Russian Clinical Laboratory Diagnostics 66, no. 5 (May 23, 2021): 310–14. http://dx.doi.org/10.51620/0869-2084-2021-66-5-310-314.

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The aim of the study was to assess the informative value of volatile fatty acid parameters for the differential diagnosis of infected pancreatic necrosis (IPN), complicated by retroperitoneal cellulitis. The work was based on the results of examination and treatment of 44 patients with infected pancreatic necrosis. The analysis of concentrations of volatile fatty acids: acetic, propionic, butyric and isovalerianic was carried out on a Kristallux-4000 automated gas chromatograph with an HP-FFAP capillary column and a flame ionization detector. The indicators of acetic acid and the amount of volatile fatty acids were statistically significantly higher in patients with infected pancreatic necrosis with total retroperitoneal phlegmons in comparison with the indicators of volatile fatty acids in patients with infected pancreatic necrosis with paracolic phlegmons and in comparison with indicators of volatile fatty acids in patients with infected pancreatic necrosis phlegmons. The indicators of acetic acid and the amount of VFA can be used as additional criteria for the differential diagnosis of IPN complicated by phlegmons of the retroperitoneal tissue.

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Ryczer, Teresa, Katarzyna Męczkowska, and Artur Niedzielski. "Craniofacial and neck phlegmon with sepsis as a complication of the parotid gland abscess – a case report." Wiedza Medyczna 1, no. 1 (August 13, 2019): 12–15. http://dx.doi.org/10.36553/wm.14.

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The diagnosis of acute bacterial parotitis usually does not cause much clinical concern due to the characteristic clinical signs and symptoms, such as pain and swelling of parotid gland associated with fever and elevated inflammatory markers in laboratory tests. Early diagnosis and accurate treatment result in fast recovery without complications. In rare cases, acute bacterial parotitis may cause severe complications, such as parotid gland abscess or parapharyngeal space phlegmon. Parapharyngeal space phlegmon is a severe, life-threatening condition. It can spread to craniofacial and neck fascial spaces, mediastinum, and lead to sepsis and septic shock. Craniofacial and neck phlegmon requires prompt surgical treatment and intensive antibiotic therapy. In this case study, we present an 82-year-old woman with bacterial parotitis that resulted in multiple complications. The first complication was parotid gland abscess, which caused extended craniofacial and neck phlegmon that led to sepsis. As a result of immediate intensive treatment, which consisted of broad-spectrum antibiotic therapy, surgical drainage, and hydro-electrolyte imbalance management, the treatment ended in a success. The patient fully recovered and was discharged home in a good general condition.

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Chiu, L., J. Digby-Bell, J. Seah, S. Melton, K. Taylor, and M. Sparrow. "P594 Utilisation of anti-TNF agents in phlegmonous Crohn’s disease: an Australian tertiary referral centre experience." Journal of Crohn's and Colitis 15, Supplement_1 (May 1, 2021): S542—S543. http://dx.doi.org/10.1093/ecco-jcc/jjab076.715.

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Abstract Background Phlegmonous Crohn’s disease (CD) is a complication of penetrating disease where traditional management was surgical. There are a paucity of studies evaluating its medical management. The aim of our single-centre, retrospective case series was to evaluate the efficacy and safety of anti-TNF therapy in managing phlegmonous CD. Methods Cases were identified through searching patient records for CT, MRI and intestinal ultrasound reports containing the words “Crohn’s” and “phlegmon”. Patients were included if found to have CD-related phlegmon subsequently started on anti-TNF. Patients were excluded if they were already on an anti-TNF at diagnosis, or underwent surgery prior to starting anti-TNF. Electronic review of patient records was undertaken to determine demographics, current medication, length of disease and surgery. Results Of the 66 cases identified, 11 fulfilled inclusion criteria. 2 cases required surgery at 38 and 197 days post-phlegmon diagnosis, both of which had earlier ceased anti-TNF due to failed trial and severe depression respectively. 4 patients discontinued anti-TNF during follow up: 1 experienced severe anaphylaxis, 1 failed anti-TNF trial, and 2 ceased due to personal preference (severe depression, concern about adverse effects). 8 of 10 had complete resolution of the phlegmon with 1 patient awaiting imaging 6 months post-phlegmon diagnosis. Conclusion 9 of 11 of our patient cohort avoided surgery after starting anti-TNF therapy for phlegmonous CD, out to a median follow up of 20 months. Our findings suggest anti-TNFs are generally well tolerated, and early commencement may be effective in preventing surgical intervention.

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Warshaw, Andrew L. "Can Pancreatic Phlegmon be Diagnosed?" HPB Surgery 2, no. 4 (January 1, 1990): 300–302. http://dx.doi.org/10.1155/1990/68631.

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Kallel, S., H. Hadj Taieb, S. Makni, and A. Ghorbel. "Phlegmon périamygdalien révélant un lymphome." Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale 130, no. 6 (December 2013): 340–42. http://dx.doi.org/10.1016/j.aforl.2013.02.018.

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Fan, Sheung-tat, Tat-kuen Choi, Fu-luk Chan, Edward C. S. Lai, and John Wong. "Pancreatic phlegmon: What is it?" American Journal of Surgery 157, no. 6 (June 1989): 544–47. http://dx.doi.org/10.1016/0002-9610(89)90695-8.

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Merzlikin, N. N., A. V. Kuznetsov, V. I. Barabash, and R. V. Sorokin. "Method of drainage of retroperitoneal fat at infected pancreatonecrosis." Bulletin of Siberian Medicine 9, no. 3 (June 28, 2010): 117–20. http://dx.doi.org/10.20538/1682-0363-2010-3-117-120.

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The aim of this study was to improve the results of treatment of patients with infected pancreatonecrosis complicated with phlegmon of retroperitoneal fat. Toward this end, the following tasks were formulated: to develop a new way of drainage of the retroperitoneal fat at infected pancreatonecrosis — retroperitoneostomy and to analyze comparatively the efficiency of traditional methods of drainage of the pancreatic gland zone at infected pancreatonecrosis (omnetobursotomy, lumbostomy) with retroperitoneostomy.The analysis was based on the results of examination and treatment of 60 patients with pancreatonecrosis complicated with phlegmon of retroperitoneal fat, who were operated in surgical departments of the Tomsk municipal hospital no. 3 in 2004—2008.The use of retroperitoneostomy in the treatment of infected pancreatonecrosis complicated with phlegmon of retroperitoneal fat decreased postsurgical complications from 36.6 to 15.79% and lethality from 56.1 to 21,0%.

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Żyluk, Andrzej, Piotr Puchalski, and Zbigniew Szlosser. "Results of the treatment of phlegmon of Streptococcus pyogenes aetiology within upper limbs." Pomeranian Journal of Life Sciences 66, no. 4 (February 1, 2020): 46–49. http://dx.doi.org/10.21164/pomjlifesci.747.

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Abstract Phlegmon is a purulent infection which spreads in loose connective tissue. It occurs most commonly in the limbs as a complication of other local infections. Untreated or inadequately treated infections in the skin of the fingers or hands are susceptible to phlegmon. In most cases, the infecting organism is Staphylococcus aureus. This article reports 7 cases of phlegmon involving upper limbs, caused by the Streptococcus pyogenes organism. The course of these types of infection are more serious, and the range of tissue damage greater, than those caused by staphylococci. This article presents the causes of the phlegmon, the methods and course of management, and the results of these. The principles of surgical management include wide incisions in the skin and an evacuation of pus and necrotic tissue debris. The skin is then sealed with stitches or a skin graft once the wound is clean. Of the 7 treated patients, 1 died in the intensive care unit due to sepsis and mutli-organ failure and 1 patient lost his all fingers due to necrosis. The authors believe that it is desirable that doctors working in emergency units and surgical admission rooms should be familiar with the basic rules of diagnosing and managing these potentially life-threatening or hand crippling disease

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SUNDBERG, HENRI. "Über Gastritis phlegmonosa." Nordiskt Medicinskt Arkiv 51, no. 18 (April 24, 2009): 303–68. http://dx.doi.org/10.1111/j.0954-6820.1918.tb00583.x.

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Elsner, P., and J. Meyer. "Verspätet erkannte Phlegmone bei diabetischem Fußsyndrom." Aktuelle Dermatologie 46, no. 12 (July 31, 2020): 546–50. http://dx.doi.org/10.1055/a-1205-3180.

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ZusammenfassungEin Patient mit insulinpflichtigem Diabetes mellitus Typ II und diabetischer Polyneuropathie entwickelte akut eine vesikulöse Hautveränderung am linken Fuß, die von einem Dermatologen unter der Diagnose eines Herpes simplex antiviral behandelt wurde. Erst mit 14-tägiger Verzögerung erfolgte die Diagnoseänderung als bakterielle Infektion und nach Wundabstrich eine interne Antibiose. Weitere diagnostische oder therapeutische Maßnahmen, außer Verbandswechsel mit lokaler Anwendung von antibakteriellen Kompressen, wurden nicht durchgeführt. Unter zunehmender Verschlechterung des Befundes und der Diagnose Phlegmone Vorfuß links wurde der Patient in eine chirurgische Praxis und dann in eine Klinik für Gefäßchirurgie überwiesen, wo es nach Amputation der 3. Zehe links sowie Nekrektomie mit offener Wundbehandlung und erregerspezifischer Antibiose über mehrere Monate zur Abheilung kam.Die Schlichtungsstelle stellte einen groben Behandlungsfehler aufgrund des Verkennens der Diagnose, des nicht ausreichenden Einbezuges weiterführender diagnostischer Maßnahmen, einer nicht stadiengerechten Wundtherapie und fehlender Wundkontrollen fest. Nach Einschätzung der Schlichtungsstelle ist von einem schweren Fehler auszugehen. Ein schwerer Behandlungsfehler, der generell geeignet ist, einen Schaden der tatsächlich eingetretenen Art herbeizuführen, führt grundsätzlich zu einer Umkehr der objektiven Beweislast für den ursächlichen Zusammenhang zwischen dem Behandlungsfehler und dem primären Gesundheitsschaden.Infektionen auf dem Boden eines diabetischen Fußsyndroms sind mit einer hohen Morbidität und Mortalität behaftet. Da sie klinisch blande verlaufen können, sollten bei jedem Verdacht eine engmaschige Wundkontrolle sowie eine leitliniengerechte Diagnostik und Therapie erfolgen. In der Zusammenarbeit mit pflegerischen Wundmanagern ist zu klären, ob diese in Delegation des Arztes oder in eigenständiger Verantwortung tätig werden können. Für die ärztliche Dokumentation ist bei der Versorgung von Patienten mit chronischen Wunden der Dermatologe selbst verantwortlich.

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Paramonova, Olesya Andreevna, Y. P. Savchenko, T. V. Gayvoronskaya, E. A. Terman, T. V. Gerbova, and D. I. Tsinenko. "IMPROVED LOCAL TREATMENT WITH WOUND COVERING IN PATIENTS WITH FACE AND NECK PHLEGMONS REGARDING WOUND PROCESS PHASE." Russian Journal of Dentistry 22, no. 1 (February 15, 2018): 36–40. http://dx.doi.org/10.18821/1728-2802-2018-22-1-36-40.

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Clinical and microbiological analysis of «Aquacel Ag + Hydrofiber dressing», «Aquacel Ag Foam dressing Hydrofiber» and «Granulex» (ConvaTec, USA; wound covering efficiency in complex treatment of patients with face and neck phlegmons was carried out. We proved positive influence and potent action of the wound dressing on reparative processes in postoperative purulent wounds in patients with face and neck phlegmons. Application of «Aquacel Ag + Hydrofiber dressing», «Aquacel AgFoam Hydrofiber dressing» and «Granuflex» wound covering in a complex therapy allowed to improve wound condition in earlier terms, put secondary sutures and reduce terms of patient hospital stay.

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43

Abraham, Ned, Anthony Eyers, and Nimalan Pathma-Nathan. "Acute diverticular phlegmon in colonic neovagina." ANZ Journal of Surgery 74, no. 9 (September 2004): 809–10. http://dx.doi.org/10.1111/j.1445-1433.2004.03159.x.

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Muradbegovic, Mirza, Pénélope St-Amour, David Martin, David Petermann, Samir Benabidallah, and Luca Di Mare. "End-colostomy diverticulitis with parastomal phlegmon." Medicine 96, no. 43 (October 2017): e8358. http://dx.doi.org/10.1097/md.0000000000008358.

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Carter, John M., Amit Patel, Sean S. Evans, Meredith Lakey, and Kimsey H. Rodriguez. "Retropharyngeal phlegmon in Rosai Dorfman disease." International Journal of Pediatric Otorhinolaryngology 78, no. 2 (February 2014): 373–76. http://dx.doi.org/10.1016/j.ijporl.2013.11.019.

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Serbin, A. S., I. A. Maksutin, О. Yu Afanasyeva, S. V. Dronov, T. E. Kozenko, and K. A. Aleshanov. "Cytokine regulation of immune status of patients of older age groups with odontogenic phlegmon of maxillofacial region on background of immunocorrective therapy." Medical alphabet, no. 3 (June 12, 2020): 43–44. http://dx.doi.org/10.33667/2078-5631-2020-3-43-44.

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The influence of the immunomodulator azoximer bromide has been studied on the cytokine regulation of immune status at elderly and senile patients with the odontogenic phlegmon of the maxillofacial region. Clinical and immunological studies of 95 elderly and senile patients with the odontogenic phlegmon of the maxillofacial region were carried out. The authors has been shown including in the scheme of traditional treatment of this disease of azoximer bromide allows to normalize the cytokine regulation of immune status, that enhances the effectiveness of treatment and decreases the term of the patients’ treatment at the hospital.

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47

Boev, I. A., G. I. Straube, G. I. Antakov, and A. P. Godovalov. "Endogenous intoxication in patients with face phlegmons." Clinical Dentistry, no. 1 (2018): 54–57. http://dx.doi.org/10.37988/1811-153x_2018_1_54.

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Debrie, J. E. "Nerf médian et phlegmons des gaines digitocarpiennes." Annales de Chirurgie de la Main 4, no. 3 (January 1985): 242–45. http://dx.doi.org/10.1016/s0753-9053(85)80008-9.

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Gromov, Alexander L., M. A. Gubin, S. V. Ivanov, and D. S. Tishkov. "ANALYSIS OF THE DEPENDENCE BETWEEN THE NUMBER OF INVOLVED INVOLVED IN THE INFLAMMATORY PROCESS CELLULAR SPACES, DEPTH OF LESION AND PRESENCE OF ORGAN FAILURE IN PATIENTS WITH ODONTOGENIC INFLAMMATORY DISEASES OF MAXILLOFACIAL AREA AND NECK." Russian Journal of Dentistry 22, no. 3 (June 15, 2018): 133–38. http://dx.doi.org/10.18821/1728-2802-2018-22-3-133-138.

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Introduction. In the diagnosis and subsequent treatment of patients with phlegmons of the maxillofacial region and neck, a large number of errors are allowed, which leads to the growth of neglected extensive purulent processes. Goal. Increasing the effectiveness of diagnosis of acute odontogenic inflammatory diseases. Material and methods. The first block of research. To determine the relationship between the number of cell spaces involved in the odontogenic inflammatory process, the depth of lesion and the presence of organ failure, a group of patients (480 patients) with acute odontogenic inflammatory diseases of the maxillofacial region and neck were analyzed. The following indicators were evaluated: the number of facial and neck cell spaces involved in the inflammatory process, the depth of the lesion, as well as the presence of organ failure. The second block of research. To evaluate the effectiveness of the developed algorithm for determining the high probability of development of organ failure, the developed algorithm was tested on a group of patients with odontogenic inflammatory diseases (64 patients). An indicator of the effectiveness of early diagnosis and prediction of odontogenic organ failure was assessed (when the patient entered the hospital). Results. Between the involvement of deep cellular spaces of the maxillofacial region and the presence of organ failure there is a direct dependence. In patients with organ failure, lesions of 4 or more cellular spaces are most often observed. Discussion. To determine the high probability of development of organ failure, it is possible to study the number of involved cell spaces and / or the depth of lesion. For more purposeful observation, this technique should not be used in isolation, but must be combined with other methods of effective diagnosis. The conclusion. Phlegmon, which spreads to 4 or more cellular spaces, and / or involves the deep cellular spaces of the maxillofacial region, the cellular spaces of the neck, the mediastinum, is characterized by a high risk of organ failure.

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Agatieva, Elima, Said Ksembaev, Mikhail Sokolov, Vage Markosyan, Ilnaz Gazizov, Dmitry Tsyplakov, Maxim Shmarov, et al. "Evaluation of Direct and Cell-Mediated Lactoferrin Gene Therapy for the Maxillofacial Area Abscesses in Rats." Pharmaceutics 13, no. 1 (January 4, 2021): 58. http://dx.doi.org/10.3390/pharmaceutics13010058.

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Resistance to antibacterial therapy requires the discovery of new methods for the treatment of infectious diseases. Lactoferrin (LTF) is a well-known naïve first-line defense protein. In the present study, we suggested the use of an adenoviral vector (Ad5) carrying the human gene encoding LTF for direct and cell-mediated gene therapy of maxillofacial area phlegmon in rats. Abscesses were developed by injection of the purulent peritoneal exudate in the molar region of the medial surface of the mandible. At 3–4 days after phlegmon maturation, all rats received ceftriaxone and afterward were subcutaneously injected around the phlegmon with: (1) Ad5 carrying reporter gfp gene encoding green fluorescent protein (Ad5-GFP control group), (2) Ad5 carrying LTF gene (Ad5-LTF group), (3) human umbilical cord blood mononuclear cells (UCBC) transduced with Ad5-GFP (UCBC + Ad5-GFP group), and (4) UCBC transduced with Ad5-LTF (UCBC + Ad5-LTF group). Control rats developed symptoms considered to be related to systemic inflammation and were euthanized at 4–5 days from the beginning of the treatment. Rats from therapeutic groups demonstrated wound healing and recovery from the fifth to seventh day based on the type of therapy. Histological investigation of cervical lymph nodes revealed purulent lymphadenitis in control rats and activated lymphatic tissue in rats from the UCBC + Ad5-LTF group. Our results propose that both approaches of LTF gene delivery are efficient for maxillofacial area phlegmon recovery in rats. However, earlier wound healing and better outcomes in cervical lymph node remodeling in the UCBC + Ad5-LTF group, as well as the lack of direct exposure of the viral vector to the organism, which may cause toxic and immunogenic effects, suggest the benefit of cell-mediated gene therapy.

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Journal articles on the topic 'Phlegmona'

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