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Dissertations / Theses on the topic 'Phosphate ceramics'

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1

Sreeram, Attiganal Narayanaswamy. "Topological disorder in phosphate and other ceramics." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/32679.

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Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1995.<br>Includes bibliographical references (leaves 146-157).<br>by Attiganal Narayanaswamy Sreeram.<br>Sc.D.
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2

Jensen, Amy S. "Phosphate bonding of ceramic hollow sphere foams." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/19444.

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3

Langstaff, Sarah Dorthea. "Calcium phosphate ceramics capable of supporting osteoclastic resorption." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0005/NQ42953.pdf.

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4

Walsh, Pamela Judith. "Natural calcium phosphate ceramics for tissue engineering application." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486236.

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There is a great need for new bone graft materials. Bone related problems have increased considerably over the last few decades, owing to an ageing populate and the associated prevalence of bone disease. The traditional method of grafting to bridge bone defects are still widely used, despite a wide selection of new synthetic alternatives materials becoming available. These tend to lack the physical properties, such as porosity, interconnective and mechanical strength required for bone repair. Coral derived CaP ceramics have shown good potential, as substitute materials, offering the desirable
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5

De, Mestral François. "Calcium phosphate glasses and glass-ceramics for medical applications." Thesis, McGill University, 1986. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=65405.

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6

Qadri, Syed Jalaluddin. "Phosphate and vanadate ceramics with xenotime and monazite structures." Thesis, University of Warwick, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406808.

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7

Lloyd, Michael Charles. "The dissolution of soluble phosphate glasses." Thesis, University of Leeds, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293799.

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8

Shaw, Lindsey Ann. "The development of chemical bonding systems for refractories/ceramics." Thesis, Keele University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341290.

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9

Berg, Camilla. "Influence of Magnesium in theFormation of Phosphate Spheres : A simple method for the fabrication of sphericalparticles of calcium and magnesium phosphate." Thesis, Uppsala universitet, Oorganisk kemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-326255.

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Calcium phosphates and recently also magnesium phosphates, are used for medical applications, due to their biocompatibility and bioactivity. These properites makes spherical particles of calcium and magnesium phosphate suitable for carrier materials for drug delivery applications. By creating porous and/or hollow particles itis possible to load the particles with a drug and control therelease of the active substance. In this work, an ion-induced method for the synthesis of spherical calcium and magnesium phosphates was developed. A simple precipitation reaction was used, where substituting mag
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10

Gallinetti, Sara. "New approaches in calcium phosphate cements and ceramics for bone regeneration." Doctoral thesis, Universitat Politècnica de Catalunya, 2014. http://hdl.handle.net/10803/279558.

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Bone is among the most frequently transplanted tissues in the body. In Europe, about one million patients encounter a surgical bone reconstruction annually. The worldwide market of bone replacement materials is currently estimated at 5 billion Euros, with a 10% growth due to the ageing of the population. Natural grafts present several drawbacks which pushed scientists to investigate synthetic biomaterials. Although most synthetic bone substitutes available possess some of the positive properties of autografts, none yet have all the benefits of one's own bone. Among the available biomaterials,
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11

Zhang, Xing. "Preparation and characterization of calcium phosphate ceramics and Composites as bone substitutes." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3294744.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed January 11, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 143-155).
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12

Martin, Richard Alan. "Properties of rare earth phosphate glasses and rare-earth halide liquids." Thesis, University of Bath, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248113.

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13

Olsson, Mirja. "Chemical stability of grain boundariesin β-tricalcium phosphate ceramics : β-TCP as bone substitute material". Thesis, Uppsala universitet, Institutionen för kemi - Ångström, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173285.

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β – Tricalcium phosphate (β-TCP, Ca3(PO4)2) is a commonly used bone substitute material due to its biocompatibility and resorption. This study focused on the production of almost fully dense β-TCP ceramics with varying degrees of impurities (Ca/PO4 ratio, addition of 5% Mg). Three methods were used to produce the β-TCP ceramics, uniaxial pressing, slip-casting and isostatic pressing. In this study the isostatic pressing and sintering at 1150ºC for 20h and 15min, resulted in the densest β-TCP ceramics (97.7-99.2%). No significant differences of grain size and density could be detected between t
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14

Zhou, Gang. "ZnSe ceramics and phosphate glasses for optical applications in the visible and infrared ranges." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S071/document.

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Une étude en deux parties a été effectuée sur la préparation et la caractérisation de céramiques de ZnSe et de verres de phosphate à des fins optiques. Pour préparer des poudres de ZnSe, deux voies de synthèse ont été utilisées: i) hydrothermales; ii) le broyage à billes. La taille des particules ainsi que leur morphologie a été analysée par différentes techniques (DRX, MEB…). Ensuite, deux technologies de frittage, pressage à chaud (HP) et frittage flash (SPS), ont été mises en œuvre pour obtenir des échantillons massifs de ZnSe optiquement transparents. La meilleure transmission obtenue dans
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Hadzifejzovic, Emina. "Electrical and structural aspects of Li-ion conducting phosphate based glasses and glass ceramics." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408396.

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16

Hassan, Senin Bin. "The elastic and nonlinear acoustic vibrational properties of vitreous SiO2 and rare earth phosphate glasses." Thesis, University of Bath, 1994. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238739.

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17

Schlosser, Margarete [Verfasser], Hans-Joachim [Akademischer Betreuer] Kleebe, and Christoph [Akademischer Betreuer] Schüth. "Vapor transport sintering of calcium phosphate ceramics / Margarete Schlosser. Betreuer: Hans-Joachim Kleebe ; Christoph Schüth." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2012. http://d-nb.info/1106453352/34.

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18

Lee, Goonhee. "Selective laser sintering of calcium phosphate materials for orthopedic implants /." Digital version accessible at:, 1997. http://wwwlib.umi.com/cr/utexas/main.

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19

Casey, Brian Paul. "Novel fabrication techniques for the production of porous biphasic calcium phosphate ceramics for bone substitute application." Thesis, University of Bath, 2003. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760834.

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20

Metsger, Dean Scott. "The characterization of the biological and mechanical properties of porous calcium phosphate ceramics used as bone implants /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487759055156703.

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21

Bhatt, Himesh A. "Synthesis and Characterization of Nanocrystalline Hydroxyapatite Powder; And the Effects of Oxide-Based Sintering Additives on Tricalcium Phosphate." Master's thesis, University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3567.

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Calcium phosphate (CP) materials have been used extensively for bone replacement and augmentation due to their similarity to the mineral component of bone. In addition to being non-toxic, they are biocompatible, not recognized as foreign materials in vivo, and most importantly, exhibit osteoconductive behavior, being able to help in bone formation during healing. CPs form an intimate physicochemical bond with the host tissue, termed osseointegration. However the main limitation of calcium phosphates is their inherent brittle nature and poor mechanical performance under complex stress states. A
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22

Kim, Hyunbin. "Synthesis and control of microstructure, mechanical properties, and bioactivity in biphasic and preferentially oriented calcium phosphate bioceramics." Birmingham, Ala. : University of Alabama at Birmingham, 2007. http://www.mhsl.uab.edu/dt/2007p/kim.pdf.

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23

Bernard, Sheldon Ainsworth. "Influence of silicon dioxide, magnesium oxide and zinc oxide on resorbable tricalcium phosphate based bioceramics." Online access for everyone, 2005. http://www.dissertations.wsu.edu/Thesis/Fall2005/s%5Fbernard%5F083005.pdf.

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24

Rewinkel, Scott Everett. "The effects of SiO₂, ZnO, and MgO doping on the mechanical and biological properties of beta-tricalcium phosphate bioceramics for bone tissue engineering, in vitro and in vivo analysis." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Fall2009/s_rewinkel_100909.pdf.

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Thesis (M.S. in mechanical engineering)--Washington State University, December 2009.<br>Title from PDF title page (viewed on Jan. 22, 2010). "School of Mechanical and Materials Engineering." Includes bibliographical references (p. 123-128).
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25

Dasgupta, Sudip. "Nanostructured hydroxyapatite and tricalcium phosphate based ceramics for bovine serum albumin protein delivery and bone implants using microwave sintering." Online access for everyone, 2008. http://www.dissertations.wsu.edu/Dissertations/Summer2008/S_Dasgupta_073008.pdf.

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26

Karvat, Franciele. "Elaboração e caracterização de biomateriais : matriz de cálcio e compósitos fosfato de cálcio/Al2O3a Sol-Gel para aplicação como implante e regeneração óssea." Universidade do Estado de Santa Catarina, 2005. http://tede.udesc.br/handle/handle/1661.

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Made available in DSpace on 2016-12-08T17:19:23Z (GMT). No. of bitstreams: 1 Resumo_Abstract.pdf: 35434 bytes, checksum: 4a34b93b68ea9438424d2b7000f35123 (MD5) Previous issue date: 2005-11-24<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Bone defects arise from many causes including traumas, infections, tumors and congenital deformations. They are the main problems in orthodontic and orthopedic surgical clinics. In the last few years it was verified that porous ceramics are more and more used in medical applications such as substitution and regeneration of bone tissues, m
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27

Švec, Jiří. "Fosfátová pojiva v žáruvzdorné aplikaci." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2015. http://www.nusl.cz/ntk/nusl-234573.

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The doctoral thesis is focused on the study, research and development of refractories with phosphate bonding. Primary motivation is preparation of phosphate-based binders that can be applied for non-shaped insulating material fabricated by “in situ” foaming. The phosphate binders based on Al2O3-H3PO4 system are one of the most common in refractory technology. The amphoteric nature of the aluminium and its oxides require the setting of Al2O3-H3PO4 binders under the higher temperatures. Application of higher temperatures is necessary to obtain the minimal manipulation strength of as-prepared gre
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28

Garcia, Perez Delabat Javier. "PCL-Calcium Phosphate 3D Printed Scaffolds For Bone Tissue Regeneration." Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-81735.

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The design and selection of a biomaterial will depend on its specific application and the required properties for that application, both mechanical physicochemical properties. Biomaterials can be extremely helpful in order to treat and help the human body to heal and repair faster any kind of fracture produced in bones. Calcium phosphate scaffolds produced by sol-gel procedures have been used for this purpose with a great success regarding mechanical properties and biocompatibility. This is the reason why new techniques needs to be developed to be able to produce scaffolds in a faster way and
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Leal, Claudenete Vieira 1972. "Desenvolvimento e avaliação 'in vitro' de um cimento de fosfato de calcio." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263426.

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Orientador: Cecilia Amelia de Carvalho Zavaglia<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecanica<br>Made available in DSpace on 2018-08-07T21:15:57Z (GMT). No. of bitstreams: 1 Leal_ClaudeneteVieira_M.pdf: 5685507 bytes, checksum: 57585e6d19469dc1898123b62c967679 (MD5) Previous issue date: 2006<br>Resumo: Os cimentos ósseos a base de fosfato de cálcio são materiais cerâmicos que apresentam biocompatibilidade devido a sua composição química semelhante à dos ossos, e bioatividade, promovendo a osteocondução. Com essas características, é possível a
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Ajaxon, Ingrid. "Can Bone Void Fillers Carry Load? : Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios." Doctoral thesis, Uppsala universitet, Tillämpad materialvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316656.

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Calcium phosphate cements (CPCs) are used as bone void fillers and as complements to hardware in fracture fixation. The aim of this thesis was to investigate the possibilities and limitations of the CPCs’ mechanical properties, and find out if these ceramic bone cements can carry application-specific loads, alone or as part of a construct. Recently developed experimental brushite and apatite cements were found to have a significantly higher strength in compression, tension and flexion compared to the commercially available CPCs chronOS™ Inject and Norian® SRS®. By using a high-resolution measu
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Cardoso, Hugo Ananias Inacio 1987. "Cimento de Alfa-TCP com diferentes aditivos = cinética da reação de cura, propriedades mecânicas e avaliação da citotoxicidade." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263531.

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Orientador: Cecília Amélia de Carvalho Zavaglia<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica<br>Made available in DSpace on 2018-08-16T10:16:29Z (GMT). No. of bitstreams: 1 Cardoso_HugoAnaniasInacio_M.pdf: 2818479 bytes, checksum: da321661ca9b0a8e7a14c33315a67151 (MD5) Previous issue date: 2010<br>Resumo: Os cimentos ósseos à base de fosfato de cálcio são biomateriais cerâmicos biorreabsorvíveis utilizados na substituição e no reparo de tecido ósseo danificado. Apresentam uma série de atrativos, como excelente biocompatibilidade e capacidade
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Wijesinghe, Dayanjan. "Ceramide Kinase and Ceramide-1-Phosphate." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1621.

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Ceramide-1-phosphate (C1P) is a bioactive lipid that has been implicated in many biological processes. Our laboratory has conclusively demonstrated its role in inflammation via activation of cPLA2α. The only known enzyme to date responsible for direct synthesis of C1P is ceramide kinase. Very little was known about this enzyme in terms of its enzyme kinetics and substrate specificity. As CERK is an enzyme that acts on membrane lipids, its kinetics cannot be studied using standard bulk dilutions methods. Thus we developed a surface dilution approach using Triton X 100 mixed micelles for studyin
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Duarte, Cláudia Regina Appio. "Avaliação da citotoxicidade in vitro de composições de fosfato de cálcio para uso em reparação óssea." Universidade do Estado de Santa Catarina, 2015. http://tede.udesc.br/handle/handle/950.

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Made available in DSpace on 2016-12-08T16:24:22Z (GMT). No. of bitstreams: 1 PGCA15MA177.pdf: 755005 bytes, checksum: d47e1b3be9b01d28494b49fd777da7f7 (MD5) Previous issue date: 2015-07-20<br>The nanostructured calcium phosphate bioceramics have shown importance in bone repair biomaterials for its chemical and crystallographic similarity with bone tissue crystalline structure, increasing their relevance in orthopedics, dentistry and bone healing. These biomaterials have interconnected microporous nanostructure, made of thin grains and micropores, which favor their use as synthetic matrix in
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Khan, Yusuf M. Laurencin Cato T. "Development of a polymer/ceramic composite scaffold for bone tissue engineering /." Philadelphia, Pa. : Drexel University, 2005. http://dspace.library.drexel.edu/handle/1860/470.

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35

Cassiano, Gaspar Stefania. "Mise en forme par extrusion de supports de catalyseurs à base d'alumine et à microstructure multi-échelles : Effet de la composition granulaire et du liant sur les propriétés des matériaux." Thesis, Lyon, INSA, 2013. http://www.theses.fr/2013ISAL0056/document.

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L'empilement maîtrisé de granules de différentes tailles est un concept utilisé dans la plupart de procédés de mise en forme de matériau. Cette organisation hiérarchique est connue pour améliorer les propriétés d'écoulement à l'étape de mise en forme et les caractéristiques mécaniques du matériau final. Il est apparu intéressant d'appliquer ce concept à la mise en forme par extrusion de supports de catalyseurs avec des petites (2 µm) et grosses (19 µm) granules d'alumine poreuse dont l'assemblage est assurée par un liant traditionnel, la boehmite peptisée et neutralisée, ou par un liant plus o
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Hill, Alexandra. "Thermodynamic and Morphological Properties of Ceramide-1-Phosphate Model Monolayer Systems." Kent State University Honors College / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1291831964.

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Leerssen, Robert Douglas. "Iron phosphate glass for the vitrification of INEEL sodium bearing waste and Hanford low activity waste." Diss., Rolla, Mo. : University of Missouri-Rolla, 2002. http://scholarsmine.mst.edu/thesis/pdf/Leerssen_Thesis_09007dcc805618fa.pdf.

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Thesis (M.S.)--University of Missouri--Rolla, 2002.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed August 25, 2008) Includes bibliographical references.
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RIBEIRO, CHRISTIANE. "Processamento e caracterizacao de ceramicas a base de hidroxiapatita e fosfato-tricalcico." reponame:Repositório Institucional do IPEN, 2003. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11058.

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Loutou, Mohamed. "Granulats à base de boues de phosphates : transformations thermiques, propriétés physiques et application." Thesis, Toulon, 2015. http://www.theses.fr/2015TOUL0016/document.

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Des agrégats à base des boues de phosphate de la zone de Gantour ( Youssoufia,Maroc) sont cuits à des températures comprises entre 900 et 1200°C, et examinés par différentes techniques (DRX, MEB, analyses thermique et dilatométrique, et spectroscopie d’impédance). Les propriétés physiques des agrégats (retrait, absorption d’eau et résistance à la compression) sont mesurées et corrélées, dans certains cas, aux facteurs expérimentaux(température, temps de cuisson, teneur de l’additif), et ce en utilisant la méthodologie de la recherche expérimentale.Les agrégats amendés à l’argile smectitique so
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Hassan, S. M. Mahmudul. "Development of Novel High Strength Composite Calcium Phosphate Cement for Orthopedic Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533212629435654.

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Subramanian, Preeti. "Role of Ceramide-1-Phosphate as a Specific and Potent Activator of Group IVA Cytosolic Phospholipase A2 Alpha." VCU Scholars Compass, 2007. http://hdl.handle.net/10156/1404.

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Cordaro, Nicholas Michael. "Accelerated bone bonding to calcium phosphate ceramic coated strain gauges: An experimental and computational study." Thesis, The University of Arizona, 2000. http://hdl.handle.net/10150/278724.

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Calcium phosphate ceramic (CPC) coated strain gauges have been used for long term in vivo bone strain measurements but require 6 to 9 weeks for sufficient bonding. PepTite2000™, OP-1, TGF-β1, Ca₂SO₄·2H₂O, and an endothelial cell layer with and without TGF-β1 were examined as enhancements to accelerate bone to CPC bonding. Young male Sprague-Dawley rats were implanted with gauges for three weeks and calcein labeled. Following euthanasia, their femurs were explanted and mechanically tested. Histology was completed. Optical Coherence Tomography (OCT) was studied as an alternative to histology. A
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Gariboldi, Maria Isabella. "Effect of calcium phosphate ceramic architectural features on the self-assembly of microvessels in vitro." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/283005.

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One of the greatest obstacles to clinical translation of bone tissue engineering is the inability to effectively and efficiently vascularise scaffolds. This limits the size of defects that can be repaired, as blood perfusion is necessary to provide nutrient and waste exchange to tissue at the core of scaffolds. The goal of this work was to systematically explore whether architecture, at a scale of hundreds of microns, can be used to direct the growth of microvessels into the core of scaffolds. A pipeline was developed for the production of hydroxyapatite surfaces with controlled architecture.
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Santos, Rodrigo Brandão Medeiros dos. "Síntese e caracterização de pós nanoestruturados de fosfato de cálcio e nanocompósitos hidroxiapatita/sílica-gel." Universidade do Estado de Santa Catarina, 2009. http://tede.udesc.br/handle/handle/1750.

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Made available in DSpace on 2016-12-08T17:19:34Z (GMT). No. of bitstreams: 1 Parte 01 - Revisao Bibliografica.pdf: 888360 bytes, checksum: 212c15e8818de6b2dfa60bb2cd835592 (MD5) Previous issue date: 2009-12-18<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The loss of an organ or a part of the body generates, besides the loss of function, social and psychological disorders. The materials used to replace bone fall into a class called biomaterials and should have physical and biological properties compatible with living tissue hosts. The objective of this study is to optimiz
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Cui, Yuantao [Verfasser], and H. J. [Akademischer Betreuer] Seifert. "Phosphate based ceramic as solid-state electrolyte for lithium ion batteries / Yuantao Cui ; Betreuer: H. J. Seifert." Karlsruhe : KIT-Bibliothek, 2018. http://d-nb.info/1170230482/34.

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Lacerda, Kassio André. "Obtenção de matrizes bioabsorvíveis à base de hidroxiapatita para aplicação em braquiterapia." CNEN - Centro de Desenvolvimento da Tecnologia Nuclear, Belo Horizonte, 2006. http://www.bdtd.cdtn.br//tde_busca/arquivo.php?codArquivo=2.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>O objetivo deste trabalho foi a síntese e a caracterização físico-química e microestrutural de matrizes cerâmicas porosas à base de hidroxiapatita de cálcio, bem como a avaliação de um pó de hidroxiapatita comercial, com potencialidade para atuarem como matrizes para incorporação de radionuclídeos de fontes radioativas para uso em braquiterapia. Pós de hidroxiapatita de cálcio foram sintetizados por via co-precipitativa de soluções precursoras de cálcio e fosfato em meio básico. As matrizes correspondentes foram obtidas a partir
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Jiang, Zhiping. "CHARACTERIZATION OF PHOSPHOINOSITIDE AND SPHINGOLIPID DOMAIN FORMATION IN MODEL MEMBRANES." Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1291046490.

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48

Rieck, Michael [Verfasser]. "The role of ceramide synthase 2 in sphingosine-1-phosphate-mediated thymic egress / Michael Rieck." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1149154152/34.

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49

Saito, Lia 1989. "Estudo da biocompatibilidade in-vitro e In-vivo de cimento de [Alfa]-fosfato tricálcico : diferentes tempos e processos de moagem." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/263501.

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Abstract:
Orientador: Cecília Amélia de Carvalho Zavaglia<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica<br>Made available in DSpace on 2018-08-24T06:22:47Z (GMT). No. of bitstreams: 1 Saito_Lia_M.pdf: 10338325 bytes, checksum: 36e37affce64dade6095d6f2d7761537 (MD5) Previous issue date: 2013<br>Resumo: A necessidade de substituintes ósseos está crescendo rapidamente no campo da cirurgia reconstrutiva. Os cimentos à base de fosfato de cálcio são largamente empregados no reparo do tecido ósseo devido a uma série de propriedades atrativas, como excelente b
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50

MacKnight, Patrick. "The interaction between ceramide-1-phosphate and Group IVA cytosolic phospholipase A2 and its role in wound healing." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5633.

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Abstract:
The sphingolipid, ceramide-1-phosphate (C1P), directly binds and activates Group IVA cytosolic phospholipase A2 (cPLA2a) to generate eicosanoids. Due to the role of eicosanoids in wound healing, we choose to use our novel genetic mouse model expressing cPLA2a with an ablated C1P interaction site (KI) to examine the cPLA2a/C1P interaction in wound healing. Wound closure rate was not affected, but wound maturation was dramatically enhanced by loss of the C1P/cPLA2α interaction based on the following findings. Wounds in KI mice displayed: i) increased infiltration of dermal fibroblasts into the w
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