Relevant bibliographies by topics / Photo-uncaging

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Photo-uncaging'

Author: Grafiati
Published: 14 September 2024
Last updated: 31 July 2025

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Journal articles on the topic "Photo-uncaging"

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Perdue, Lacey A., Priscilla Do, Andrew Chyong, et al. "Chemical modification strategies for photo-induced control of immune cell signaling." Journal of Immunology 204, no. 1_Supplement (2020): 221.1. http://dx.doi.org/10.4049/jimmunol.204.supp.221.1.

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Abstract Cytokine therapies show great potential to induce cancer immune elimination and have demonstrated therapeutic benefit in a subset of patients. However, controlling the pleotropic effects of these immune signal effectors is a challenge. Here, we present an approach to enable optical control of cytokine activity by caging the activity of these proteins via labeling with wavelength-specific, photo-labile polymers (i.e. photo-caging). We create a system to measure light-induced polymer cleavage (uncaging) through fluorescence dequenching and establish: high wavelength-selectivity, protein
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Sambath, Karthik, Tinghan Zhao, Zhaoxiong Wan, and Yuanwei Zhang. "Photo-uncaging of BODIPY oxime ester for histone deacetylases induced apoptosis in tumor cells." Chemical Communications 55, no. 94 (2019): 14162–65. http://dx.doi.org/10.1039/c9cc07199g.

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Ford, Peter C., Issa Frigino, James R. Tinsley, and John A. DiBenedetto. "Coupling nitric oxide photo-uncaging with radiotherapy." Coordination Chemistry Reviews 535 (July 2025): 216630. https://doi.org/10.1016/j.ccr.2025.216630.

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Ichimura, Hideo, Kaushik Parthasarathi, Jens Lindert, and Jahar Bhattacharya. "Lung surfactant secretion by interalveolar Ca2+ signaling." American Journal of Physiology-Lung Cellular and Molecular Physiology 291, no. 4 (2006): L596—L601. http://dx.doi.org/10.1152/ajplung.00036.2006.

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Although clusters of alveoli form the acinus, which is the most distal respiratory unit, it is not known whether interalveolar communication coordinates acinar surfactant secretion. To address this, we applied real-time digital imaging in conjunction with photo-excited Ca2+ uncaging in intact alveoli of the isolated, blood-perfused rat lung. We loaded alveolar cells with the Ca2+ cage o-nitrophenyl EGTA-AM (NP-EGTA-AM) together with the fluorophores, fluo 4, or LysoTracker green (LTG) to determine, respectively, the cytosolic Ca2+ concentration ([Ca2+]cyt) or type 2 cell secretion. To uncage C
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Wang, Haopei, and Zachary T. Ball. "A photochemical C=C cleavage process: toward access to backbone N-formyl peptides." Beilstein Journal of Organic Chemistry 17 (December 15, 2021): 2932–38. http://dx.doi.org/10.3762/bjoc.17.202.

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Photo-responsive modifications and photo-uncaging concepts are useful for spatiotemporal control of peptides structure and function. While side chain photo-responsive modifications are relatively common, access to photo-responsive modifications of backbone N–H bonds is quite limited. This letter describes a new photocleavage pathway, affording N-formyl amides from vinylogous nitroaryl precursors under physiologically relevant conditions via a formal oxidative C=C cleavage. The N-formyl amide products have unique properties and reactivity, but are difficult or impossible to access by traditiona
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de Sousa, Aurideia P., Ana C. S. Gondim, Eduardo H. S. Sousa, et al. "An unusual bidentate methionine ruthenium(II) complex: photo-uncaging and antimicrobial activity." JBIC Journal of Biological Inorganic Chemistry 25, no. 3 (2020): 419–28. http://dx.doi.org/10.1007/s00775-020-01772-5.

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Lee, Shin-Rong, Paul J. Adams, and David T. Yue. "Large Ca2+-dependent facilitation of CaV2.1 channels revealed by Ca2+photo-uncaging." Journal of Physiology 593, no. 13 (2015): 2753–78. http://dx.doi.org/10.1113/jp270091.

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Rong Lee, Shin, Manu B. Johny, and David T. Yue. "Large Ca2+-Dependent Facilitation of CaV2.1 Channels Induced by Ca2+ Photo-Uncaging." Biophysical Journal 104, no. 2 (2013): 461a. http://dx.doi.org/10.1016/j.bpj.2012.11.2549.

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Höglinger, Doris, André Nadler, Per Haberkant, et al. "Trifunctional lipid probes for comprehensive studies of single lipid species in living cells." Proceedings of the National Academy of Sciences 114, no. 7 (2017): 1566–71. http://dx.doi.org/10.1073/pnas.1611096114.

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Lipid-mediated signaling events regulate many cellular processes. Investigations of the complex underlying mechanisms are difficult because several different methods need to be used under varying conditions. Here we introduce multifunctional lipid derivatives to study lipid metabolism, lipid−protein interactions, and intracellular lipid localization with a single tool per target lipid. The probes are equipped with two photoreactive groups to allow photoliberation (uncaging) and photo–cross-linking in a sequential manner, as well as a click-handle for subsequent functionalization. We demonstrat
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Leonidova, Anna, Vanessa Pierroz, Riccardo Rubbiani, et al. "Photo-induced uncaging of a specific Re(i) organometallic complex in living cells." Chemical Science 5, no. 10 (2014): 4044. http://dx.doi.org/10.1039/c3sc53550a.

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Dissertations / Theses on the topic "Photo-uncaging"

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Labro, Marine. "Synthèse de nouvelles prodrogues photoactivables ciblant les G-quadruplexes : étude de la photoréaction et design moléculaire pour améliorer la biocompatibilité et l'efficacité d'une nouvelle thérapie anti-cancer." Electronic Thesis or Diss., Lyon, École normale supérieure, 2024. http://www.theses.fr/2024ENSL0020.

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Le cancer est un problème de santé publique majeur : en 2020, il a causé la mort d’environ 10 millions d’individus dans le monde soit l’équivalent d’une mort sur six. Les recherches récentes contre le cancer ont conduit à l’émergence de thérapies innovantes plus ciblées. Ainsi, les dommages collatéraux aux cellules saines et donc les effets secondaires chez les patients traités sont limités, tout en garantissant une efficacité maximale du traitement pour l’éradication de la tumeur. Dans ces travaux de thèse, nous étudions une nouvelle réaction photochimique originale permettant le développemen
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Klausen, Maxime. "Nouvelles sondes moléculaires photo-activées pour la délivrance de principes actifs : de la conception aux applications biologiques." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0077.

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La photolibération d'agents biologiques cagés par des groupements protecteurs photolabiles (PPGs) a récemment attiré un intérêt croissant en thérapie et physiologie. La combinaison de cet outil avec les avantages de l'absorption à deux photons (2PA) dans le proche IR est cependant un défi. Dans ces travaux, nous présentons deux voies différentes vers de nouveaux décageurs efficaces en 2PA.Nous élaborons d’abord une série de systèmes tandem basés sur le FRET, combinant des antennes quadrupolaires 2PA avec des modules PPGs appropriés. La modification des blocs constitutifs de ces composés nous a
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Dubois, Victor. "Nouveaux outils moléculaires photo-activables pour la délivrance contrôlée de principes actifs : De la conception aux applications biologiques." Thesis, Bordeaux, 2021. http://www.theses.fr/2021BORD0029.

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Les groupements protecteurs photolabiles (GPPs) sont de petits chromophores organiques capables de libérer des molécules bioactives à la suite d’une irradiation lumineuse. L’utilisation de ces outils attire depuis une quarantaine d’années un intérêt croissant en biologie pour des applications telles que la thérapie ou la physiologie. Bien que performants en excitation à 1-photon, l’élaboration de GPPs performants en excitation à 2- photon (E2P) dans le proche IR reste encore à ce jour un défi de taille. Dans ces travaux, nous choisissons d’adopter deux approches différentes afin d
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Book chapters on the topic "Photo-uncaging"

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Ford, Peter C. "Adventures in the photo-uncaging of small molecule bioregulators." In Advances in Inorganic Chemistry. Elsevier, 2022. http://dx.doi.org/10.1016/bs.adioch.2022.04.002.

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Conference papers on the topic "Photo-uncaging"

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Sinton, David, and Dongqing Li. "Microscale Flow Visualization." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-39577.

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A combined experimental and numerical analysis technique for velocity profiles in liquid microchannel flows is described. The working fluids employed are aqueous solutions with caged fluorescent dyes. A sheet of fluorescent dye is photo-injected by briefly exposing a cross-section of the fluid to ultraviolet light. The transport of the resulting ‘band’ of fluorescent dye is imaged onto a CCD camera using an epi-illumination fluorescent microscope system. The velocity profile is calculated from images acquired and processed after each uncaging event. The analysis technique utilizes several imag
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