Academic literature on the topic 'Photoacoustic Imaging (PAI)'

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Journal articles on the topic "Photoacoustic Imaging (PAI)"

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Yang, Xuanjin, and Liangzhong Xiang. "Photoacoustic imaging of prostate cancer." Journal of Innovative Optical Health Sciences 10, no. 04 (2017): 1730008. http://dx.doi.org/10.1142/s1793545817300087.

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Photoacoustic imaging (PAI), also known as optoacoustic imaging, is a rapidly growing imaging modality with potential in medical diagnosis and therapy monitoring. This paper focuses on the techniques of prostate PAI and its potential applications in prostate cancer detection. Transurethral light delivery combined with transrectal ultrasound detection overcomes light scattering in the surrounding tissue and provides optimal photoacoustic signals while minimizing invasiveness. While label-free PAI based on endogenous contrast has promising potential for prostate cancer detection, exogenous contr
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Liu, Yu Bin, Zhi Fang Li, Wen Ming Xie, Hui Li, Wei R. Chen, and Hai Yu Chen. "Feasibility Study of Photoacoustic Imaging for Monitoring Temperature in Photothermal Therapy." Advanced Materials Research 760-762 (September 2013): 872–75. http://dx.doi.org/10.4028/www.scientific.net/amr.760-762.872.

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Photothermal therapy relies on the principle of converting light energy into heat causing localized lesion destruction. For safe and effective treatment, it is necessary to monitor temperature diffusion in the boundaries of the irradiated region, to minimize damage to surrounding normal tissues. This paper gives a pilot study of the feasibility of photoacoustic imaging for monitoring temperature changes during photothermal therapy. The results showed that our system of photoacoustic imaging (PAI) can play the role of biosensor, for the photoacoustics signal amplitude depend on temperature of t
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Wang, Haoran, Yifei Ma, Hao Yang, Huabei Jiang, Yingtao Ding, and Huikai Xie. "MEMS Ultrasound Transducers for Endoscopic Photoacoustic Imaging Applications." Micromachines 11, no. 10 (2020): 928. http://dx.doi.org/10.3390/mi11100928.

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Photoacoustic imaging (PAI) is drawing extensive attention and gaining rapid development as an emerging biomedical imaging technology because of its high spatial resolution, large imaging depth, and rich optical contrast. PAI has great potential applications in endoscopy, but the progress of endoscopic PAI was hindered by the challenges of manufacturing and assembling miniature imaging components. Over the last decade, microelectromechanical systems (MEMS) technology has greatly facilitated the development of photoacoustic endoscopes and extended the realm of applicability of the PAI. As the k
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Jung, Doyoung, Suhyeon Park, Changho Lee, and Hyungwoo Kim. "Recent Progress on Near-Infrared Photoacoustic Imaging: Imaging Modality and Organic Semiconducting Agents." Polymers 11, no. 10 (2019): 1693. http://dx.doi.org/10.3390/polym11101693.

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Over the past few decades, the photoacoustic (PA) effect has been widely investigated, opening up diverse applications, such as photoacoustic spectroscopy, estimation of chemical energies, or point-of-care detection. Notably, photoacoustic imaging (PAI) has also been developed and has recently received considerable attention in bio-related or clinical imaging fields, as it now facilitates an imaging platform in the near-infrared (NIR) region by taking advantage of the significant advancement of exogenous imaging agents. The NIR PAI platform now paves the way for high-resolution, deep-tissue im
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Yoo, Su, Doyoung Jung, Jung-Joon Min, Hyungwoo Kim, and Changho Lee. "Biodegradable Contrast Agents for Photoacoustic Imaging." Applied Sciences 8, no. 9 (2018): 1567. http://dx.doi.org/10.3390/app8091567.

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Over the past twenty years, photoacoustics—also called optoacoustics—have been widely investigated and, in particular, extensively applied in biomedical imaging as an emerging modality. Photoacoustic imaging (PAI) detects an ultrasound wave that is generated via photoexcitation and thermoelastic expansion by a short nanosecond laser pulse, which significantly reduces light and acoustic scattering, more than in other typical optical imaging and renders high-resolution tomographic images with preserving high absorption contrast with deep penetration depth. In addition, PAI provides anatomical an
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Wang, Yuanmao, Yang Chen, Yongjian Zhao, and Siyu Liu. "Compressed Sensing for Biomedical Photoacoustic Imaging: A Review." Sensors 24, no. 9 (2024): 2670. http://dx.doi.org/10.3390/s24092670.

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Photoacoustic imaging (PAI) is a rapidly developing emerging non-invasive biomedical imaging technique that combines the strong contrast from optical absorption imaging and the high resolution from acoustic imaging. Abnormal biological tissues (such as tumors and inflammation) generate different levels of thermal expansion after absorbing optical energy, producing distinct acoustic signals from normal tissues. This technique can detect small tissue lesions in biological tissues and has demonstrated significant potential for applications in tumor research, melanoma detection, and cardiovascular
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Zhao, Zuomin, and Teemu Myllylä. "Recent Technical Progression in Photoacoustic Imaging—Towards Using Contrast Agents and Multimodal Techniques." Applied Sciences 11, no. 21 (2021): 9804. http://dx.doi.org/10.3390/app11219804.

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For combining optical and ultrasonic imaging methodologies, photoacoustic imaging (PAI) is the most important and successful hybrid technique, which has greatly contributed to biomedical research and applications. Its theoretical background is based on the photoacoustic effect, whereby a modulated or pulsed light is emitted into tissue, which selectively absorbs the optical energy of the light at optical wavelengths. This energy produces a fast thermal expansion in the illuminated tissue, generating pressure waves (or photoacoustic waves) that can be detected by ultrasonic transducers. Researc
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He, Cailing, Jiayuan Zhu, Huayue Zhang, Ruirui Qiao, and Run Zhang. "Photoacoustic Imaging Probes for Theranostic Applications." Biosensors 12, no. 11 (2022): 947. http://dx.doi.org/10.3390/bios12110947.

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Photoacoustic imaging (PAI), an emerging biomedical imaging technology, capitalizes on a wide range of endogenous chromophores and exogenous contrast agents to offer detailed information related to the functional and molecular content of diseased biological tissues. Compared with traditional imaging technologies, PAI offers outstanding advantages, such as a higher spatial resolution, deeper penetrability in biological tissues, and improved imaging contrast. Based on nanomaterials and small molecular organic dyes, a huge number of contrast agents have recently been developed as PAI probes for d
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Das, Avishek, Arthur C. M. V. Pereira, Anton A. Popov, et al. "Plasmonically enhanced two-photon absorption induced photoacoustic microscopy with laser-synthesized TiN nanoparticles." Applied Physics Letters 121, no. 8 (2022): 083701. http://dx.doi.org/10.1063/5.0101658.

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Combining photonic excitation and acoustic detection, photoacoustic imaging (PAI) presents one of the most promising noninvasive biomedical diagnostic modalities, but this technique still lacks efficient nano-sized contrast agents absorbing light in the region of relative tissue transparency (630–900 nm). Here, we explore the use of titanium nitride (TiN) nanoparticles (NPs) fabricated by methods of pulsed laser ablation in liquids as a contrast agent in PAI. When prepared in acetone, the NPs are spherical, have an average size of 25 nm, and exhibit a broad plasmonic absorption peak around 700
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Liu, Liming, and Huan Qin. "Photoacoustic molecular imaging with functional nanoparticles." Journal of Innovative Optical Health Sciences 10, no. 04 (2017): 1730004. http://dx.doi.org/10.1142/s179354581730004x.

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Photoacoustic imaging (PAI) breaks through the optical diffusion limit by making use of the PA effect. By converting incident photons into ultrasonic waves, PAI combines high contrast of optical imaging and high spatial resolution in depth tissue of ultrasound imaging in a single imaging modality. This imaging modality has now shown potential for molecular imaging, which enables visualization of biological processes with systemically introduced functional nanoparticles. In the current review, the potentials of different optical nanoprobes as PAI contrast agents were elucidated and discussed.
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Dissertations / Theses on the topic "Photoacoustic Imaging (PAI)"

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Liu, Xiaojing. "Optical Coherence Photoacoustic Microscopy (OC-PAM) for Multimodal Imaging." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/3189.

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Optical coherence tomography (OCT) and Photoacoustic microscopy (PAM) are two noninvasive, high-resolution, three-dimensional, biomedical imaging modalities based on different contrast mechanisms. OCT detects the light backscattered from a biological sample either in the time or spectral domain using an interferometer to form an image. PAM is sensitive to optical absorption by detecting the light-induced acoustic waves to form an image. Due to their complementary contrast mechanisms, OCT and PAM are suitable for being combined to achieve multimodal imaging. In this dissertation, an optical coh
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Braz, Gil Eduardo Rocha. "Modeling key uncertainties in technology development: the case of twente photoacoustic mammoscope (PAM)." Master's thesis, 2013. http://hdl.handle.net/10451/10531.

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Tese de mestrado integrado em Engenharia Biomédica e Biofísica, apresentada à Universidade de Lisboa, através da Faculdade de Ciências, 2013<br>O efeito fotoacústico foi apresentado pela primeira vez por Alexander Graham Bell em 1880. Este princípio enuncia que a absorção de ondas eletromagnéticas por um certo meio provoca uma sequência de eventos que culmina na geração de ondas sonoras. Desde a sua descoberta surgiram inúmeras aplicações fotoacústicas, entre as quais aplicações de imagiologia médica. Estes sistemas fotoacústicos utilizam os componentes óticos como sondas e os componentes acús
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Book chapters on the topic "Photoacoustic Imaging (PAI)"

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Mueller, Romy, Wilfred Ngwa, and Juergen Hesser. "Nanoparticle detection using photoacoustic imaging (PAI)." In Nanoparticle Enhanced Radiation Therapy. IOP Publishing, 2020. http://dx.doi.org/10.1088/978-0-7503-2396-3ch14.

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Panda, Pratyush, and Subhalaxmi Das. "Revolutionizing Medical Diagnostics." In Enhancing Medical Imaging with Emerging Technologies. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-5261-8.ch002.

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Conventional imaging modalities like CT, MRI, and x-ray have become indispensable for medical diagnosis, but continual innovation is required to overcome their limitations in terms of resolution, radiation exposure, and cost. As a leader in automated image analysis, speedier diagnosis, and personalized treatment through the analysis of large datasets and the discovery of hitherto invisible patterns, AI is simply amazing. Other than AI, new imaging modalities like dark-field radiography and photoacoustic imaging (PAI) provide distinct perspectives. Aside from that, visualization tools made poss
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Pandey, S. P., P. Jangied, T. Shukla, Tripathi A., and N. Upmanyu. "Accounts on the Nano-carrier System for Diagnosis Purposes." In Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080506123010013.

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Timely diagnosis of critical diseases, such as cancer, may help in its effective management and better survival. Several techniques like magnetic resonance imaging (MRI), computed tomography scan (CT scan), positron emission tomography (PET), photoacoustic imaging (PAI), etc. are already being used successfully, but sometimes their high cost, spatial resolution, sensitivity, and specificity (associated with the use of contrast agent) have been questionable. The distinction between benign and malignant tumours in their early stages is also a critical issue with such methods. But the use of nano
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Conference papers on the topic "Photoacoustic Imaging (PAI)"

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Yao, Junjie. "From Technology to Discovery: Deeper, Faster, and Colorful Photoacoustic Imaging in Life Sciences." In Optical Tomography and Spectroscopy. Optica Publishing Group, 2024. https://doi.org/10.1364/ots.2024.otu3d.1.

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Several technological advancements in PAI have collectively enabled fast, deep, and high-sensitivity biomedical applications and discoveries in life sciences, such as functional stroke imaging, drug testing, cancer detection, and interventional therapy. Full-text article not available; see video presentation
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Sweeney, Allison, Andrew Langley, Skye Edwards, Patrick Solomon, and Srivalleesha Mallidi. "Ultrasound-guided photoacoustic functional imaging to assess regional variations in response to vascular targeted therapies." In Clinical and Translational Biophotonics. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/translational.2024.tw3b.1.

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In this work, we investigate vascular therapy induced regional variations in vascularization and oxygenation using Ultrasound-guided photoacoustic imaging (US-PAI). The 3D images were fluence compensated and a custom regional segmentation algorithm was applied to the volumetric HbT images to segment the tumor volume into areas of high vascular density and low vascular density. Regionally evaluating the changes in blood oxygenation (StO2) and HbT reveals that sunitinib is preferentially targeting areas of low vascular density while PDT is agnostic of vascular density when administered at optima
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Nguyen, Van Phuc, Wei Qian, Xueding Wang, and Yannis M. Paulus. "In Vivo Visualization of Retinal Pigment Epithelial Cell Therapy Using Photoacoustic Microscopy, OCT, and Fluorescence Imaging." In Frontiers in Optics. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/fio.2022.fw1d.3.

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We demonstrates the capability of multimodal photoacoustic microscopy (PAM), optical coherence tomography (OCT), and Fluorescence Imaging for tracking of transplanted ARPE-19 cells after transplantation in living rabbits.
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Ahmed, Umayr, Van Phuc Nguyen, Josh Zhe, et al. "Combination of Photoacoustic and Optical Coherence Tomography imaging modalities for visualization of Laser induced Choroidal Neovascularization Progression in Pigmented Rabbits." In Frontiers in Optics. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/fio.2023.jm4a.89.

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This study presents a novel multimodality photoacoustic microscopy (PAM) and optical coherence tomography (OCT) imaging techniques for longitudinal visualization of laser induced choroidal neovascularization (CNV) pathogenesis in pigmented rabbits.
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Nguyen, Van Phuc, Wei Qian, Josh Zhe, et al. "Ultraminiature Gold Nanochains for Multimodal Photoacoustic Microscopy, OCT, and Fluorescence Molecular Imaging of Choroidal Neovascularization." In Frontiers in Optics. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/fio.2023.jm4a.85.

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We present novel ultraminiature gold nanochains as contrast agents for enhanced visualization of choroidal neovascularization using multimodal photoacoustic microscopy (PAM), optical coherence tomography (OCT), and fluorescence imaging in living rabbits.
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Nguyen, Van Phuc, Wen Fan, Tianye Zhu, et al. "Multimodal Photoacoustic Microscopy, Optical Coherence Tomography, and Fluorescence in vivo Tracking of Stem Cells." In CLEO: Applications and Technology. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.am5i.1.

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We present a novel method for longitudinal tracking of transplanted stem cells in the subretinal space in a living rabbit using multimodal photoacoustic microscopy (PAM), optical coherence tomography (OCT), and fluorescence imaging.
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Gargesha, Madhusudhana, Shreya Goel, Bryan Scott, Mark D. Pagel, and Debashish Roy. "Abstract LB239: CryoVizTMand photoacoustic imaging for assessment of tumor vasculature in mouse models of pancreatic tumors." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-lb239.

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