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1

Nemec, Sebastjan, Slavko Kralj, Claire Wilhelm, Ali Abou-Hassan, Marie-Pierre Rols, and Jelena Kolosnjaj-Tabi. "Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles’ Heating Yield." Applied Sciences 10, no. 20 (October 19, 2020): 7322. http://dx.doi.org/10.3390/app10207322.

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Photothermal therapy is gathering momentum. In order to assess the effects of the encapsulation of individual or clustered superparamagnetic iron oxide nanoparticles (SPIONs) on nanoparticle light-to-heat conversion, we designed and tested individual and clustered SPIONs encapsulated within a silica shell. Our study compared both photothermia and magnetic hyperthermia, and it involved individual SPIONs as well as silica-encapsulated individual and clustered SPIONs. While, as expected, SPION clustering reduced heat generation in magnetic hyperthermia, the silica shell improved SPION heating in photothermia.
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2

Pacheco, Ana Rita F., Ana Margarida Barros, Carlos O. Amorim, Vítor S. Amaral, Paulo J. G. Coutinho, Ana Rita O. Rodrigues, and Elisabete M. S. Castanheira. "Elastic Liposomes Containing Calcium/Magnesium Ferrite Nanoparticles Coupled with Gold Nanorods for Application in Photothermal Therapy." Nanomaterials 14, no. 8 (April 15, 2024): 679. http://dx.doi.org/10.3390/nano14080679.

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This work reports on the design, development, and characterization of novel magneto-plasmonic elastic liposomes (MPELs) of DPPC:SP80 (85:15) containing Mg0.75Ca0.25Fe2O4 nanoparticles coupled with gold nanorods, for topical application of photothermal therapy (PTT). Both magnetic and plasmonic components were characterized regarding their structural, morphological, magnetic and photothermal properties. The magnetic nanoparticles display a cubic shape and a size (major axis) of 37 ± 3 nm, while the longitudinal and transverse sizes of the nanorods are 46 ± 7 nm and 12 ± 1.6 nm, respectively. A new methodology was employed to couple the magnetic and plasmonic nanostructures, using cysteine as bridge. The potential for photothermia was evaluated for the magnetic nanoparticles, gold nanorods and the coupled magnetic/plasmonic nanoparticles, which demonstrated a maximum temperature variation of 28.9 °C, 33.6 °C and 37.2 °C, respectively, during a 30 min NIR-laser irradiation of 1 mg/mL dispersions. Using fluorescence anisotropy studies, a phase transition temperature (Tm) of 35 °C was estimated for MPELs, which ensures an enhanced fluidity crucial for effective crossing of the skin layers. The photothermal potential of this novel nanostructure corresponds to a specific absorption rate (SAR) of 616.9 W/g and a maximum temperature increase of 33.5 °C. These findings point to the development of thermoelastic nanocarriers with suitable features to act as photothermal hyperthermia agents.
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Beltran, Osvaldo, Mariangel Luna, Marisol Gastelum, Alba Costa-Santos, Adriana Cambón, Pablo Taboada, Marco A. López-Mata, Antonio Topete, and Josue Juarez. "Novel Gold Nanorods@Thiolated Pectin on the Killing of HeLa Cells by Photothermal Ablation." Pharmaceutics 15, no. 11 (November 2, 2023): 2571. http://dx.doi.org/10.3390/pharmaceutics15112571.

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Gold nanorods (AuNRs) have attracted attention in the field of biomedicine, particularly for their potential as photothermal agents capable of killing tumor cells by photothermic ablation. In this study, the synthesis of novel AuNRs stabilized with thiolated pectin (AuNR@SH-PEC) is reported. To achieve this, thiolated pectin (SH-PEC) was obtained by chemically binding cysteamine motifs to the pectin backbone. The success of the reaction was ascertained using FTIR-ATR. Subsequently, the SH-PEC was used to coat and stabilize the surface of AuNRs (AuNR@SH-PEC). In this context, different concentrations of SH-PEC (0.25, 0.50, 1.0, 2.0, 4.0, and 8.0 mg/mL) were added to 0.50 mL of AuNRs suspended in CTAB, aiming to determine the experimental conditions under which AuNR@SH-PEC maintains stability. The results show that SH-PEC effectively replaced the CTAB adsorbed on the surface of AuNRs, enhancing the stability of AuNRs without affecting their optical properties. Additionally, scanning electron and atomic force microscopy confirmed that SH-PEC is adsorbed into the surface of the AuNRs. Importantly, the dimension size (60 × 15 nm) and the aspect ratio (4:1) remained consistent with those of AuNRs stabilized with CTAB. Then, the photothermal properties of gold nanorods were evaluated by irradiating the aqueous suspension of AuNR@SH-PEC with a CW laser (808 nm, 1 W). These results showed that photothermal conversion efficiency is similar to the photothermal conversion observed for AuNR-CTAB. Lastly, the cell viability assays confirmed that the SH-PEC coating enhanced the biocompatibility of AuNR@SH-PEC. Most important, the viability cell assays subjected to laser irradiation in the presence of AuNR@SH-PEC showed a decrease in the cell viability relative to the non-irradiated cells. These results suggest that AuNRs stabilized with thiolated pectin can potentially be exploited in the implementation of photothermal therapy.
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Qin, Jiamin, Jingqi Zhang, Guojuan Fan, Xiaoxia Wang, Yuzhong Zhang, Ling Wang, Yapei Zhang, et al. "Cold Atmospheric Plasma Activates Selective Photothermal Therapy of Cancer." Molecules 27, no. 18 (September 13, 2022): 5941. http://dx.doi.org/10.3390/molecules27185941.

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Due to the body’s systemic distribution of photothermal agents (PTAs), and to the imprecise exposure of lasers, photothermal therapy (PTT) is challenging to use in treating tumor sites selectively. Striving for PTT with high selectivity and precise treatment is nevertheless important, in order to raise the survival rate of cancer patients and lower the likelihood of adverse effects on other body sections. Here, we studied cold atmospheric plasma (CAP) as a supplementary procedure to enhance selectivity of PTT for cancer, using the classical photothermic agent’s gold nanostars (AuNSs). In in vitro experiments, CAP decreases the effective power of PTT: the combination of PTT with CAP at lower power has similar cytotoxicity to that using higher power irradiation alone. In in vivo experiments, combination therapy can achieve rapid tumor suppression in the early stages of treatment and reduce side effects to surrounding normal tissues, compared to applying PTT alone. This research provides a strategy for the use of selective PTT for cancer, and promotes the clinical transformation of CAP.
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5

Shakhov, P. V., G. V. Tikhonowski, E. A. Popova-Kuznetsova, A. Yu Zakharkiv, E. V. Gromushkina, S. M. Klimentov, and A. A. Popov. "Studying IR Photohyperthermia Sensitized by Titanium Nitride Nanoparticles Using Tissue-Equivalent Phantoms." Meditsinskaya Fizika 94, no. 2 (July 12, 2022): 85–95. http://dx.doi.org/10.52775/1810-200x-2022-94-2-85-95.

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Purpose: To use tissue-equivalent phantom for studies of thermal fields in biological tissues during IR photo hyperthermia with plasmonic titanium nitride nanoparticles (TiN NPs). Material and methods: Gel phantom based on polyacrylamide (PAA) with addition of naphtol green dye and intralipid 10% was created. Optical properties (reduced scattering coefficient) of phantom ingredients were determined using added absorber technique. Thermal field distribution was studied with IR thermal imaging technique. 50 nm plasmonic TiN NPs, synthetized by laser ablation in liquids, were used as sensitizers of photothermic action. Photothermal experiments were performed using two phantoms: a phantom with homogeneous optical parameters, which are relevant to biological tissues (absorption coefficient µa=0.35 сm-1, reduced scattering coefficient µ's=30 сm-1), and a phantom containing 0.02 mg/ml of TiN NPs, which increased absorption coefficient by Dµa=0.65 сm-1. The part of phantom with the NPs was located under 5 mm layer of NPs-free phantom. Photothermal effect was excited by CW laser irradiation of 830 nm wavelength and 16 W/cm2 intensity (900 mW, beam diameter: 1.3 mm) for 2 min. Thermal field distribution inside the phantom was measured by IR thermal camera. Results: A tissue-equivalent gel phantom with independently tunable absorption and scattering coefficients was designed. The phantom had cubic shape with 30 30 30 mm size. Results of photothermal experiments showed that the use of TiN NPs as sensitizers IR photohyperthermia leads to a significant increase in tissue temperature (up to 5 degrees Celsius) at distances up to 15 mm under the phantom surface. In addition, a simple experimental setup for measuring scattering coefficient of a liquid phantom ingredients was described. Conclusion: A simple method for preparation of PAA phantom for modelling photothermal heating of biological tissues and studying thermal fields distributions was described. The phantom is handy and allows one to quickly experimentally simulate the photothermal response of biological tissues, including tissues containing various spatial distributions of photosensitive NPs. TiN NPs experimentally confirmed to be an effective sensitizer of IR photothermal effect.
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6

T. S., Anilkumar, Yu-Jen Lu, and Jyh-Ping Chen. "Optimization of the Preparation of Magnetic Liposomes for the Combined Use of Magnetic Hyperthermia and Photothermia in Dual Magneto-Photothermal Cancer Therapy." International Journal of Molecular Sciences 21, no. 15 (July 22, 2020): 5187. http://dx.doi.org/10.3390/ijms21155187.

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In this work, we aimed to develop liposomal nanocomposites containing citric-acid-coated iron oxide magnetic nanoparticles (CMNPs) for dual magneto-photothermal cancer therapy induced by alternating magnetic field (AMF) and near-infrared (NIR) lasers. Toward this end, CMNPs were encapsulated in cationic liposomes to form nano-sized magnetic liposomes (MLs) for simultaneous magnetic hyperthermia (MH) in the presence of AMF and photothermia (PT) induced by NIR laser exposure, which amplified the heating efficiency for dual-mode cancer cell killing and tumor therapy. Since the heating capability is directly related to the amount of entrapped CMNPs in MLs, while the liposome size is important to allow internalization by cancer cells, response surface methodology was utilized to optimize the preparation of MLs by simultaneously maximizing the encapsulation efficiency (EE) of CMNPs in MLs and minimizing the size of MLs. The experimental design was performed based on the central composite rotatable design. The accuracy of the model was verified from the validation experiments, providing a simple and effective method for fabricating the best MLs, with an EE of 87% and liposome size of 121 nm. The CMNPs and the optimized MLs were fully characterized from chemical and physical perspectives. In the presence of dual AMF and NIR laser treatment, a suspension of MLs demonstrated amplified heat generation from dual hyperthermia (MH)–photothermia (PT) in comparison with single MH or PT. In vitro cell culture experiments confirmed the efficient cellular uptake of the MLs from confocal laser scanning microscopy due to passive accumulation in human glioblastoma U87 cells originated from the cationic nature of MLs. The inducible thermal effects mediated by MLs after endocytosis also led to enhanced cytotoxicity and cumulative cell death of cancer cells in the presence of AMF–NIR lasers. This functional nanocomposite will be a potential candidate for bimodal MH–PT dual magneto-photothermal cancer therapy.
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7

MOLINA-CORRAL, Francisco J., Miguel ESPINO-DÍAZ, Juan L. JACOBO, Scott D. MATTINSON, John K. FELLMAN, David R. SEPÚLVEDA, Gustavo A. GONZÁLEZ-AGUILAR, Nora A. SALAS-SALAZAR, and Guadalupe I. OLIVAS. "Quality attributes during maturation of ‘Golden Delicious’ and ‘Red Delicious’ apples grown in two geographical regions with different environmental conditions." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 49, no. 1 (March 24, 2021): 12241. http://dx.doi.org/10.15835/nbha49112241.

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Apples have distinctive quality attributes that may be defined by environmental conditions of the geographical regions where fruits are cultivated, such as temperature, solar radiation, photoperiod, and photothermic units. A three-year study was conducted to compare ‘Golden Delicious’ and ‘Red Delicious’ apples from two different regions, Washington, USA (WA) and Chihuahua, Mexico (CHIH). Apple samples were harvested weekly from early August to late October (~120-180 days after full bloom - DAFB), and analysed for quality parameters. Geographic environmental data were obtained, and photoperiod, solar radiation, degree-days and photothermal units were calculated. Results show quality differences between CHIH and WA apples. WA shows a ~5-week delay in apple bloom, possibly due to the lower temperatures presented in WA. Apples from both regions required the same photoperiod, ~ 2,222 h, to attain the beginning of the ripening stage, which took more days (three weeks) for CHIH apples, most likely attributed to the higher elevation of CHIH orchards (2,062 vs. 763 masl). The main distinctive quality differences found between WA and CHIH apples were firmness and aroma volatile compounds. CHIH apples presented substantially higher amounts of aroma compounds. WA apples showed greater firmness, probably due to lower photothermal units. Using all firmness data (both varieties, both growing zones) a remarkable correlation was found between firmness and photothermal units (R=0.89), which may suggest firmness could be improved by the manipulation of degree days and photoperiod, that is, temperature and light.
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8

Li, Guo, Fayan Meng, Taicheng Lu, Liying Wei, Xin Pan, Zhenzhen Nong, Mei Wei, Chuanan Liao, and Xuehua Li. "Functionalised molybdenum disulfide nanosheets for co-delivery of doxorubicin and siRNA for combined chemo/gene/photothermal therapy on multidrug-resistant cancer." Journal of Pharmacy and Pharmacology 73, no. 8 (April 21, 2021): 1128–35. http://dx.doi.org/10.1093/jpp/rgab059.

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Abstract Objective Molybdenum disulfide (MoS2) has been developed for medical uses due to its excellent medically beneficial characteristics. This research was designed to develop a multifunctional nano-drug delivery system based on the nano-structure of MoS2 for combined chemo/gene/photothermal therapy targeting multidrug-resistant cancer. Methods MoS2 nanosheets were prepared by a hydrothermal reaction and modified. Afterward, the nanocarrier was characterised. In vitro cytotoxicity of the drug delivery systems on human breast adenocarcinoma cell lines was assessed. Key findings The nanocarrier was a flake-like structure with a uniform hydrodynamic diameter and possessing good colloidal stability. The nanocarrier showed the capacity to be deployed for co-delivery of Doxorubicin (DOX) and siRNA. The release of DOX could be triggered and enhanced by pH and application of near-infrared (NIR) laser. The nanocarrier had a good photothermic response and stability. The nanocarrier had little effect on the cells and exhibited good biocompatibility. Measurement of the therapeutic efficacy showed that synergistic therapy combining chemo-, gene- and photothermal therapy deploying this drug delivery system will achieve a better anticancer effect on drug-resistant cancer cells than DOX alone. Conclusions Our results suggest that this drug delivery system has potential application in the therapeutic strategy for drug-resistant cancer.
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9

Jiang, Quzi, Luodan Yu, and Yu Chen. "Engineering Self-Assembled Nanomedicines Composed of Clinically Approved Medicines for Enhanced Tumor Nanotherapy." Nanomaterials 13, no. 18 (September 5, 2023): 2499. http://dx.doi.org/10.3390/nano13182499.

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The traditional nanocarriers are typically constructed to deliver anticancer agents for improving drug bioavailability and enhancing chemotherapeutic efficacy, but this strategy suffers from the critical issue of nanocarrier biosafety that hinders further clinical translation. In this work, a unique nanomedicine (PTX@ICG) has been rationally constructed by combining two clinically approved agents, i.e., paclitaxel (PTX) and indocyanine green (ICG), by a facile ultrasound-assisted self-assembly methodology. The formation of the nanostructure can effectively increase the enrichment of PTX and ICG molecules in the tumor site, and improve the utilization factor of hydrophobic PTX. Moreover, since the molecule interaction in PTX@ICG is mainly Van der Waals forces, the self-assembled structure can be spontaneously dissociated under laser irradiation and release PTX in situ to achieve safe tumor-targeted chemotherapy. Simultaneously, the released ICG can act as photothermic agents for photothermal therapy (PTT), thus combining chemotherapy and PTT to obtain an enhanced tumor nanotherapy via facile self-assembly. The synergistic chemo/photothermal tumor nanotherapy achieved the efficient tumor cell-killing effect and tumor-ablation ability, as systematically demonstrated both in vitro and in vivo. This work provides a distinct paradigm of the self-assembled nanomedicine design for effectively improving the drug bioavailability to achieve high antitumor efficacy.
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10

Bellardita, Marianna, Roberto Fiorenza, Luisa D'Urso, Luca Spitaleri, Antonino Gulino, Giuseppe Compagnini, Salvatore Scirè, and Leonardo Palmisano. "Exploring the Photothermo-Catalytic Performance of Brookite TiO2-CeO2 Composites." Catalysts 10, no. 7 (July 9, 2020): 765. http://dx.doi.org/10.3390/catal10070765.

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The thermocatalytic, photocatalytic and photothermo-catalytic oxidation of some volatile organic compounds (VOCs), 2-propanol, ethanol and toluene, was investigated over brookite TiO2-CeO2 composites. The multi-catalytic approach based on the synergistic effect between solar photocatalysis and thermocatalysis led to the considerable decrease in the conversion temperatures of the organic compounds. In particular, in the photothermo-catalytic runs, for the most active samples (TiO2-3 wt% CeO2 and TiO2-5 wt% CeO2), the temperature at which 90% of VOC conversion occurred was about 60 °C, 40 °C and 20 °C lower than in the thermocatalytic tests for 2-propanol, ethanol and toluene, respectively. Furthermore, the addition of cerium oxide to brookite TiO2 favored the total oxidation to CO2 already in the photocatalytic tests at room temperature. The presence of small amounts of cerium oxide allowed to obtain efficient brookite-based composites facilitating the space charge separation and increasing the lifetime of the photogenerated holes and electrons as confirmed by the characterization measurements. The possibility to concurrently utilize the photocatalytic properties of brookite and the redox properties of CeO2, both activated in the photothermal tests, is an attractive approach easily applicable to purify air from VOCs.
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Navilan, D. "Photothermal Boiling in Aqueous Nanofluids." International Journal of Trend in Scientific Research and Development Volume-2, Issue-5 (August 31, 2018): 1611–17. http://dx.doi.org/10.31142/ijtsrd17114.

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12

Fu Gege, 付格格, 卢扬 Lu Yang, 潘嘉林 Pan Jialin, 李旭 Li Xu, 王晨光 Wang Chenguang, 刘晓敏 Liu Xiaomin, and 卢革宇 Lu Geyu. "基于二维碳化钛(MXene)的光热/化疗协同治疗纳米试剂的构建及其光热效应研究." Chinese Journal of Lasers 50, no. 3 (2023): 0307204. http://dx.doi.org/10.3788/cjl221211.

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13

Gao Haofeng, 高浩锋, 李晓林 Li Xiaolin, 钮月萍 Niu Yueping, and 龚尚庆 Gong Shangqing. "光诱导原子解吸附实验中的光热效应研究." Chinese Journal of Lasers 48, no. 23 (2021): 2312001. http://dx.doi.org/10.3788/cjl202148.2312001.

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Chen, Jun, Hui Gao, Ying Bi, MengXue Zhou, and Yi Hu. "In vivo evaluation of near-infrared mediated nanoplatforms for targeted chemo-photothermal therapy and photothermo-immunotherapy." Nanomedicine: Nanotechnology, Biology and Medicine 14, no. 5 (July 2018): 1807–8. http://dx.doi.org/10.1016/j.nano.2017.11.188.

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15

Jiang, Yu, Xingchen Duan, Junhua Bai, Hongkun Tian, Dan Ding, and Yanhou Geng. "Polymerization-induced photothermy: A non-donor-acceptor approach to highly effective near-infrared photothermal conversion nanoparticles." Biomaterials 255 (October 2020): 120179. http://dx.doi.org/10.1016/j.biomaterials.2020.120179.

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16

Remilai Abulaiti, 热米莱·阿卜来提, 帕尔哈提江·吐尔孙 Paerhatijiang Tuersun, 郑玉霞 Zheng Yuxia, 马登攀 Ma Dengpan, and 程龙 Cheng Long. "Au纳米球壳的光热特性分析与优化." Laser & Optoelectronics Progress 59, no. 7 (2022): 0725001. http://dx.doi.org/10.3788/lop202259.0725001.

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Zhao, Yue, Yi Wang, Xiaoyu Wang, Ruilian Qi, and Huanxiang Yuan. "Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections." Nanomaterials 13, no. 15 (August 7, 2023): 2269. http://dx.doi.org/10.3390/nano13152269.

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Photothermal therapy has the advantages of non-invasiveness, low toxicity, simple operation, a broad spectrum of antibacterial ability, and non-proneness to developing drug resistance, which provide it with irreplaceable superiority in fighting against microbial infection. The effect of photothermal therapy is closely related to the choice of photothermal agent. Conjugated nanomaterials are potential candidates for photothermal agents because of their easy modification, excellent photothermal conversion efficiency, good photostability, and biodegradability. In this paper, the application of photothermal agents based on conjugated nanomaterials in photothermal antimicrobial treatment is reviewed, including conjugated small molecules, conjugated oligomers, conjugated polymers, and pseudo-conjugated polymers. At the same time, the application of conjugated nanomaterials in the combination of photothermal therapy (PTT) and photodynamic therapy (PDT) is briefly introduced. Finally, the research status, limitations, and prospects of photothermal therapy using conjugated nanomaterials as photothermal agents are discussed.
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Terazima, M., N. Hirota, S. E. Braslavsky, Andreas Mandelis, S. E. Bialkowski, G. J. Diebold, R. J. D. Miller, Danièle Fournier, R. A. Palmer, and A. Tam. "Quantities, terminology, and symbols in photothermal and related spectroscopies (IUPAC Recommendations 2004)." Pure and Applied Chemistry 76, no. 6 (January 1, 2004): 1083–118. http://dx.doi.org/10.1351/pac200476061083.

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This paper presents quantities, terminology, and symbols of terms related to photothermal phenomena and used in photothermal and related spectroscopies. The terms used in the literature to describe photothermal phenomena and methods are reviewed, and a glossary of terms is given. The origins of photothermal phenomena, as well as the relations among various photothermal effects, are summarized. The listed terms cover the terminology in transient grating, transient lens, photoacoustic spectroscopy, photothermal radiometry, calorimetry, interferometry, deflection, reflection, and other related spectroscopies, which use or are related to photothermal effects.
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Tee, Si Yin, Enyi Ye, Choon Peng Teng, Yuki Tanaka, Karen Yuanting Tang, Khin Yin Win, and Ming-Yong Han. "Advances in photothermal nanomaterials for biomedical, environmental and energy applications." Nanoscale 13, no. 34 (2021): 14268–86. http://dx.doi.org/10.1039/d1nr04197e.

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Highlights of various emerging inorganic photothermal nanomaterials and their up-to-date applications in photothermal therapy, photothermal sterilization, solar-driven steam generation and photothermal catalysis.
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Zhang, Haohao, Guihuan Chen, Bing Yu, and Hailin Cong. "Emerging Advanced Nanomaterials for Cancer Photothermal Therapy." REVIEWS ON ADVANCED MATERIALS SCIENCE 53, no. 2 (February 1, 2018): 131–46. http://dx.doi.org/10.1515/rams-2018-0010.

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Abstract As a new minimally invasive technique, photothermal therapy has attracted worldwide attention in the treatment of cancer. Photothermal therapy kills cancer cells by converting photon energy into heat energy. At the time of selection, the photothermal agents will be required to be water solubility, cytotoxicity, high photothermal conversion efficiency, metabolic pathway and so on. This report introduces the current research status of various nanoparticles used in photothermal therapy, and looks forward to the future development of photothermal therapy.
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Zhang, Xu, Bowen Tan, Yanting Wu, Min Zhang, and Jinfeng Liao. "A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering." Polymers 13, no. 13 (June 25, 2021): 2100. http://dx.doi.org/10.3390/polym13132100.

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Photothermal treatment (PTT) is a promising strategy to deal with multidrug-resistant bacteria infection and promote tissue regeneration. Previous studies demonstrated that hyperthermia can effectively inhibit the growth of bacteria, whereas mild heat can promote cell proliferation, further accelerating wound healing and bone regeneration. Especially, hydrogels with photothermal properties could achieve remotely controlled drug release. In this review, we introduce a photothermal agent hybrid in hydrogels for a photothermal effect. We also summarize the potential mechanisms of photothermal hydrogels regarding antibacterial action, angiogenesis, and osteogenesis. Furthermore, recent developments in photothermal hydrogels in wound healing and bone regeneration applications are introduced. Finally, future application of photothermal hydrogels is discussed. Hydrogels with photothermal effects provide a new direction for wound healing and bone regeneration, and this review will give a reference for the tissue engineering.
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Sun, Xiaohuan, Qianyun Ye, Jinfeng Zhou, Jie Han, and Rong Guo. "Host-guest assemblies for improved photothermal cancer therapy." Chemical Synthesis 3, no. 2 (2023): 16. http://dx.doi.org/10.20517/cs.2022.45.

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Photothermal cancer therapy has attracted plenty of attention in the last decades due to its promising efficacy, spatiotemporal control, negligible drug resistance, etc. However, to achieve widespread clinical application, the enhancement of curative effect and the minimization of side effect still need be concerned about in the field of photothermal therapy. Host-guest assemblies, constructed by the inclusion of small molecular guests into macrocyclic hosts through non-covalent interactions, are featured with unique microenvironment and flexible, dynamic nature. On the basis of the abovementioned advantages, host-guest assemblies show great potential in photothermal therapy. However, to the best of our knowledge, the endeavors of host-guest assemblies-based photothermal therapy have not been systematically discussed. Hence, to benefit the design of advanced host-guest assembly-based photothermal agents and promote the development of photothermal therapy, in this review, the major achievements of host-guest assemblies in photothermal cancer therapy, including the enhancement of photothermal conversion efficiency, the improvement of targeted distribution in tumor site, and the superiority of constructing photothermal therapy-derived multimodal synergistic therapy, are discussed. In addition, the future perspectives on host-guest assemblies-based photothermal therapy are outlined.
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Chen, Zeyu. "Application of Molecular Probes in Tumor Treatment." E3S Web of Conferences 271 (2021): 03028. http://dx.doi.org/10.1051/e3sconf/202127103028.

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Photothermal therapy refers to the addition of targeted drugs with photothermal effects into the patient's body. Through targeting, the drug specifically recognizes tumor cells and accumulates around tumor cells. Afterwards, it is irradiated with a laser of a specific wavelength to achieve a local temperature increase, thereby achieving the effect of killing or locating tumor cells. Therefore, the most important part of this treatment method is the photothermal probe with a targeting effect and good photothermal effect. The existing photothermal probes are mainly composed of inorganic substances, organic small molecules and organic biomolecules. This paper will mainly introduce the development status and prospects of performance of these three types of photothermal probes to introduce photothermal agent development.
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Wang, Ruizhi, Guofeng Zhou, Yuchan Yang, Shiqing Wang, Shanshan Gao, Dongmei Gao, and Xiaolin Wang. "Prostate-Specific Membrane Antigen-1-Mediated Au@SiO2@Au Core–Shell Nanoparticles: Targeting Prostate Cancer to Enhance Photothermal Therapy and Fluorescence Imaging." Journal of Biomedical Nanotechnology 18, no. 1 (January 1, 2022): 158–65. http://dx.doi.org/10.1166/jbn.2022.3229.

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The advantages of deep tissue penetration and the high spatial accuracy of photothermal therapy have been widely studied. Gold, as a photothermal material, has received particular attention. Different sizes and shapes of gold have been studied and characterized for their varying photothermal properties. The core–shell structure of gold nanoparticles and silica enhances the photothermal conversion through the coupling effect between gold clusters on the material’s surface. With excellent photothermal conversion performance, the core–shell nanoparticles can quickly reach 40 °C in 200 s under the irradiation of 808 nm, 1.5 W·cm−2. The highest conversion temperature of these nanoparticles is 56 °C, and the photothermal conversion rate is 45%. In vitro cell experiments displayed that NPs with targeted function can efficiently aggregate in prostate cancer cells and effectively kill cells. In vitro experiments showed that the tumor cells of mice after photothermal treatment completely disappeared after 15 days, which fully demonstrated the potential of the nanoparticles for targeted photothermal therapy.
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Zhu, Lin, Rui-Min Hao, Chao-Yang Chang, and Qin-Pei Wu. "Excellent Absorption of LaCoxO3 Over Full Solar Spectrum and Direct Photothermal Energy Storage of Ca(OH)2–LaCoxO3." Journal of Solar Energy Research Updates 10 (December 31, 2023): 93–101. http://dx.doi.org/10.31875/2410-2199.2023.10.09.

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Abstract: Photothermal conversion is a vital way for solar energy applications. The strong absorption of near Infrared light is essential for excellent photothermal performance. In this study, we demonstrated that nano LaCoxO3 is able to harvest light intensely across the full solar spectrum with high photothermal temperature. A core-shell-like structure of LaCoxO3-coated Ca(OH)2 particles was fabricated and shows excellent photothermal conversion, high kinetics of dehydration and remarkable cycle stability of heat storage and release. The photothermal dehydration-conversion of Ca(OH)2 increases 8.4-fold. Results demonstrate the multifunctionality of LaCoxO3, intensifying light harvesting, high photothermal conversion, good stability, considerable strength, and porous framework favouring the performance of photothermal storage and release cycles. LaCoxO3–Ca(OH)2 composite can simultaneously harvest light and store thermal energy.
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Li, Jinyang, Zhenyu Wang, Hanpeng Deng, Jiayang Li, Bin Wang, and Zuowan Zhou. "Recent advances in photothermal materials for solar-driven crude oil adsorption." Nanotechnology Reviews 11, no. 1 (January 1, 2022): 3155–64. http://dx.doi.org/10.1515/ntrev-2022-0449.

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Abstract In recent years, the adsorption method is usually adopted in the actual treatment of crude oil spills. However, the high viscosity of crude oils prevents them from diffusing into the internal pores of the adsorbent, resulting in ineffective oil capture. Photothermal materials can reduce the viscosity of crude oil by in situ heating through the photothermal conversion effect, making it easier for crude oil to occupy the internal pores of the adsorbent. At present, the review of the application of photothermal materials in the field of crude oil adsorption is still blank. This review focuses on the application of novel photothermal conversion materials in the field of crude oil adsorption and their performance comparison. Among the photothermal conversion materials used in the field of crude oil adsorption, some are commercial sponges with high porosity and photothermal coating, while others are self-assembled three-dimensional porous structures of materials with inherent photothermal properties. This review mainly introduces the types and research progress of materials with good photothermal effect at home and abroad in recent years and summarizes some new research ideas and materials that can be applied to photothermal conversion.
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Shi, Yingge, Meiying Liu, Fengjie Deng, Guangjian Zeng, Qing Wan, Xiaoyong Zhang, and Yen Wei. "Recent progress and development on polymeric nanomaterials for photothermal therapy: a brief overview." Journal of Materials Chemistry B 5, no. 2 (2017): 194–206. http://dx.doi.org/10.1039/c6tb02249a.

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Xing, Jiarui, and Huilin Li. "Photothermal Effect Based on Bionic Nanomaterials in the Treatment of Football Sports Injuries." Journal of Nanomaterials 2022 (May 20, 2022): 1–7. http://dx.doi.org/10.1155/2022/1374693.

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As more and more people love football and participate in more and more football matches, the physical injuries in the confrontation are getting more and more serious. In recent years, bionic photothermal nanomaterials have shown great application potential in disease treatment. Biomimetic photothermal nanomaterials are functional and intelligent materials with special excellent performance that are designed and synthesized by using natural biomimetic principles. Photothermal therapy (PTT) technology is a new treatment technology in recent years. On the one hand, photothermal therapy technology can convert light energy into heat energy through photothermal conversion factor (PTCA). Molecular water-soluble drugs penetrate into the skin to replace the existing injection administration methods with higher risk and low patient compliance and oral administration methods that generally cause first-pass effects, improve the utilization and efficiency of drugs, and can give provide patients with better treatment. The purpose of this article is to explore the application of the photothermal effect of bionic nanomaterials in the treatment of football sports injuries. The method adopted in this paper is to synthesize different bionic photothermal nanomaterials and synthesize bionic photothermal nanomaterials that are fused with cell membranes, thereby promoting the application of photothermal therapy technology in the treatment of sports injuries; further, by synthesizing bionics wrapped by fusion membranes, photothermal nanomaterials introduce collaborative photothermal therapy technology. The experimental results show that the photothermal effect of nanobiomimetic materials is used to treat common injuries caused by football sports. Compared with traditional treatment methods, HA-CuS gel and near-infrared treatment are applied to the skin with the injured tissue of the experimental group. It dropped to 85.7% in 2 h then gradually dropped to 84.2%, and the recovery speed was significantly accelerated.
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LIANG, Y. Q., X. F. GAO, X. J. LI, W. Q. ZHANG, and J. S. LIAN. "THE PREPARATION AND CHARACTERIZATION OF W18O49@PEG PHOTOTHERMAL AGENT." Journal of Ovonic Research 16, no. 3 (May 2020): 159–64. http://dx.doi.org/10.15251/jor.2020.163.159.

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Photothermal therapy using traditional conversion agent was limited by the complexity of cancer. It was urgent to find a new efficient and inoffensive photothermal conversion agent. Herein, we synthesized W18O49, a non-invasive and efficient photothermal conversion agent for photothermal therapy application. This work revealed that the morphology of W18O49 was changed for photothermal therapy by poly ethylene glycol (PEG) modification. Meanwhile, with 808 nm irradiation, W18O49@PEG nanoparticles could covert laser energy into hyperthermia, which could further induce cancer cells ablation.
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Wu, Zhiyi, Jiahui Shen, Chaoran Li, Chengcheng Zhang, Chunpeng Wu, Zimu Li, Xingda An, and Le He. "Niche Applications of MXene Materials in Photothermal Catalysis." Chemistry 5, no. 1 (March 6, 2023): 492–510. http://dx.doi.org/10.3390/chemistry5010036.

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MXene materials have found emerging applications as catalysts for chemical reactions due to their intriguing physical and chemical applications. In particular, their broad light response and strong photothermal conversion capabilities are likely to render MXenes promising candidates for photothermal catalysis, which is drawing increasing attention in both academic research and industrial applications. MXenes are likely to satisfy all three criteria of a desirable photothermal catalyst: strong light absorption, effective heat management, and versatile surface reactivity. However, their specific functionalities are largely dependent on their structure and composition, which makes understandings of the structure–function relationship of crucial significance. In this review, we mainly focus on the recent progress of MXene–based photothermal catalysts, emphasizing the functionalities and potential applications of MXene materials in fields of photothermal catalysis, and provide insights on design principles of highly efficient MXene–based photothermal catalysts from the atomic scale. This review provides a relatively thorough understanding of MXene–based materials for photothermal catalysis, as well as an in–depth investigation of emerging high-prospect applications in photothermal catalysis.
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Yu, Shujie, Guoyu Xia, Nan Yang, Longlong Yuan, Jianmin Li, Qingluo Wang, Dingyang Li, Lijun Ding, Zhongxiong Fan, and Jinyao Li. "Noble Metal Nanoparticle-Based Photothermal Therapy: Development and Application in Effective Cancer Therapy." International Journal of Molecular Sciences 25, no. 11 (May 22, 2024): 5632. http://dx.doi.org/10.3390/ijms25115632.

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Photothermal therapy (PTT) is a promising cancer therapy modality with significant advantages such as precise targeting, convenient drug delivery, better efficacy, and minimal adverse effects. Photothermal therapy effectively absorbs the photothermal transducers in the near-infrared region (NIR), which induces the photothermal effect to work. Although PTT has a better role in tumor therapy, it also suffers from low photothermal conversion efficiency, biosafety, and incomplete tumor elimination. Therefore, the use of nanomaterials themselves as photosensitizers, the targeted modification of nanomaterials to improve targeting efficiency, or the combined use of nanomaterials with other therapies can improve the therapeutic effects and reduce side effects. Notably, noble metal nanomaterials have attracted much attention in PTT because they have strong surface plasmon resonance and an effective absorbance light at specific near-infrared wavelengths. Therefore, they can be used as excellent photosensitizers to mediate photothermal conversion and improve its efficiency. This paper provides a comprehensive review of the key role played by noble metal nanomaterials in tumor photothermal therapy. It also describes the major challenges encountered during the implementation of photothermal therapy.
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Ma, Hui, and Mianqi Xue. "Recent advances in the photothermal applications of two-dimensional nanomaterials: photothermal therapy and beyond." Journal of Materials Chemistry A 9, no. 33 (2021): 17569–91. http://dx.doi.org/10.1039/d1ta04134g.

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The photothermal applications of 2D nanomaterials in photothermal therapy, water evaporation, thermochemical reactions, light-driven actuators, photothermal electrodes, energy storage, wearable heaters and bacterial inhibition.
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Pereira, Mélanie, Ana Rita O. Rodrigues, Leslie Amaral, Manuela Côrte-Real, Cátia Santos-Pereira, and Elisabete M. S. Castanheira. "Bovine Lactoferrin-Loaded Plasmonic Magnetoliposomes for Antifungal Therapeutic Applications." Pharmaceutics 15, no. 8 (August 19, 2023): 2162. http://dx.doi.org/10.3390/pharmaceutics15082162.

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Bovine lactoferrin (bLf) is a milk-derived protein that exhibits potent broad-spectrum antifungal activity against multiple fungi. bLf is susceptible to degradation, while some of its properties depend on the tertiary structure. So, the encapsulation of bLf in stimuli-responsive therapeutic formulations provides an added value to enhance its biological activities. Plasmonic magnetoliposomes (PMLs) arise as promising nanocarriers for dual hyperthermia (magneto-photothermia) and local chemotherapy, since the combination of magnetic and gold nanoparticles (NPs) in a single nanosystem (multifunctional liposomes) enables the targeting and controlled release of loaded drugs. In this work, plasmonic magnetoliposomes (PMLs) containing manganese ferrite nanoparticles (28 nm size) and gold nanoparticles (5–7.5 nm size), functionalized with 11-mercaptoundecanoic acid or octadecanethiol, were prepared and loaded with bLf. The NPs’ optical, magnetic and structural properties were measured via UV/vis/NIR absorption spectroscopy, SQUID and TEM, respectively. The Specific Absorption Rate (SAR) was calculated to assess the capabilities for magnetic and photothermal hyperthermia. Finally, the antifungal potential of bLf-loaded PMLs and their mechanism of internalization were assessed in Saccharomyces cerevisiae by counting the colony forming units and using fluorescence microscopy. The results demonstrate that PMLs are mainly internalized through an energy- and temperature-dependent endocytic process, though the contribution of a diffusion component cannot be discarded. Most notably, only bLf-loaded plasmonic magnetoliposomes display cytotoxicity with an efficiency similar to free bLf, attesting their promising potential for bLf delivery in the context of antifungal therapeutic interventions.
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Singer, Sebastian, and Mark Berneburg. "Phototherapie." JDDG: Journal der Deutschen Dermatologischen Gesellschaft 16, no. 9 (September 2018): 1120–31. http://dx.doi.org/10.1111/ddg.13646_g.

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Zhang, Haifeng, Shiya Zheng, Canwen Chen, and Dagan Zhang. "A graphene hybrid supramolecular hydrogel with high stretchability, self-healable and photothermally responsive properties for wound healing." RSC Advances 11, no. 11 (2021): 6367–73. http://dx.doi.org/10.1039/d0ra09106e.

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The hydrogel demonstrated properties with high stretchability, self-healable and photothermal properties. Notably, photothermal therapy could be established due to its photothermal responsiveness, benefiting infected wound healing.
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Yang, Zhuowen, Jianting Yao, Jianxin Wang, Cong Zhang, Yang Cao, Lan Hao, Chao Yang, et al. "Ferrite-encapsulated nanoparticles with stable photothermal performance for multimodal imaging-guided atherosclerotic plaque neovascularization therapy." Biomaterials Science 9, no. 16 (2021): 5652–64. http://dx.doi.org/10.1039/d1bm00343g.

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A strategy of “ferrite-encapsulated nanoparticles-mediated photothermal therapy” was proposed, which combined stable photothermal performance and multimodal imaging-guided photothermal therapeutic effect to suppress the plaque angiogenesis.
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Kumari, Sangeeta, Nilesh Sharma, and Shivendra V. Sahi. "Advances in Cancer Therapeutics: Conventional Thermal Therapy to Nanotechnology-Based Photothermal Therapy." Pharmaceutics 13, no. 8 (July 30, 2021): 1174. http://dx.doi.org/10.3390/pharmaceutics13081174.

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In this review, advancement in cancer therapy that shows a transition from conventional thermal therapies to laser-based photothermal therapies is discussed. Laser-based photothermal therapies are gaining popularity in cancer therapeutics due to their overall outcomes. In photothermal therapy, light is converted into heat to destruct the various types of cancerous growth. The role of nanoparticles as a photothermal agent is emphasized in this review article. Magnetic, as well as non-magnetic, nanoparticles have been effectively used in the photothermal-based cancer therapies. The discussion includes a critical appraisal of in vitro and in vivo, as well as the latest clinical studies completed in this area. Plausible evidence suggests that photothermal therapy is a promising avenue in the treatment of cancer.
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Li, Chaowei, Yue Cheng, Dawei Li, Qi An, Wei Zhang, Yu Zhang, and Yijun Fu. "Antitumor Applications of Photothermal Agents and Photothermal Synergistic Therapies." International Journal of Molecular Sciences 23, no. 14 (July 18, 2022): 7909. http://dx.doi.org/10.3390/ijms23147909.

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As a new tumor treatment strategy, photothermal therapy (PTT) has the advantages of accuracy, ease of administration, a high efficiency and low side effects. Photothermal transduction agents (PTAs) are the key factor which play an important role in PTT. The mechanism of PTT is discussed in detail. The photothermal conversion efficiency (PCE) can be improved by increasing the light absorption and reducing the light scattering of photothermal conversion agents. Additionally, non-radiative relaxation path attenuation can also promote energy conversion to obtain a higher value in terms of PCE. The structure and photothermal characteristics of various kinds of PTAs (metal materials, carbon-based nanomaterials, two-dimensional nanomaterials, and organic materials) were compared and analyzed. This paper reviews the antitumor applications of photothermal synergistic therapies, including PTT combined with immunotherapy, chemotherapy, and photodynamic therapy. This review proposes that these PTAs promote the development of photothermal synergistic therapies and have a great potential in the application of tumor treatment.
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Tian, Jindan, Ru Han, Qiangsheng Guo, Zhe Zhao, and Na Sha. "Direct Conversion of CO2 into Hydrocarbon Solar Fuels by a Synergistic Photothermal Catalysis." Catalysts 12, no. 6 (June 2, 2022): 612. http://dx.doi.org/10.3390/catal12060612.

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Photothermal coupling catalysis technology has been widely studied in recent years and may be a promising method for CO2 reduction. Photothermal coupling catalysis can improve chemical reaction rates and realize the controllability of reaction pathways and products, even in a relatively moderate reaction condition. It has inestimable value in the current energy and global environmental crisis. This review describes the application of photothermal catalysis in CO2 reduction from different aspects. Firstly, the definition and advantages of photothermal catalysis are briefly described. Then, different photothermal catalytic reductions of CO2 products and catalysts are introduced. Finally, several strategies to improve the activity of photothermal catalytic reduction of CO2 are described and we present our views on the future development and challenges of photothermal coupling. Ultimately, the purpose of this review is to bring more researchers’ attention to this promising technology and promote this technology in solar fuels and chemicals production, to realize the value of the technology and provide a better path for its development.
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Wang, Yaqiong, Haiyan Pan, Zhaowei Meng, and Cai Zhang. "In Situ Biosynthesis of Photothermal Parasite for Fluorescence Imaging-Guided Photothermal Therapy of Tumors." Gels 8, no. 11 (November 21, 2022): 754. http://dx.doi.org/10.3390/gels8110754.

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Photothermal therapy (PTT) has been widely known as a promising therapeutic strategy for cancer treatment in recent decades. However, some organic and inorganic photothermal agents exhibit shortcomings including potential long-term toxicity and lack of biodegradability. Biocompatible extracts from plants and animals provide several alternatives for the reformation of photothermal agents. Bio-inspired products still have inherent problems such as low accumulation in tumors, easy diffusion, and fast elimination. Herein, we aim to develop a biocompatible photothermal agent with tumor enrichment. Enlightened by “parasitized snails”, in situ biosynthesis of photothermal agents and fluorescence imaging-guided PTT are achieved with the assistance of alginate–calcium–genipin (ACG) hydrogel. ACG hydrogel is a mixture of alginate (ALG), calcium (Ca), and genipin (GP). Given that the crosslinking product of GP and protein displays fluorescent/photothermal features, the constructed ACG hydrogel can gradually react with the tumor and then “light up” and “ignite” the tumor under specific light excitation. The ACG hydrogel can be seen as a photothermal parasite, eventually leading to the death of tumor. The photothermal therapeutic effects of ACG hydrogel reacting with tumors are successfully proven in vivo. The naturally derived GP and ALG ensure the biosafety of the ACG hydrogel-based bio-application. This work is another successful practice of nature-inspired methodological strategy for in situ biosynthesis of the photothermal agent.
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Gu, Zhengye, Xiaochuan Geng, Shanyi Guang, and Hongyao Xu. "POSS Engineering of Multifunctional Nanoplatforms for Chemo-Mild Photothermal Synergistic Therapy." International Journal of Molecular Sciences 25, no. 2 (January 13, 2024): 1012. http://dx.doi.org/10.3390/ijms25021012.

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Chemo-mild photothermal synergistic therapy can effectively inhibit tumor growth under mild hyperthermia, minimizing damage to nearby healthy tissues and skin while ensuring therapeutic efficacy. In this paper, we develop a multifunctional study based on polyhedral oligomeric sesquisiloxane (POSS) that exhibits a synergistic therapeutic effect through mild photothermal and chemotherapy treatments (POSS-SQ-DOX). The nanoplatform utilizes SQ-N as a photothermal agent (PTA) for mild photothermal, while doxorubicin (DOX) serves as the chemotherapeutic drug for chemotherapy. By incorporating POSS into the nanoplatform, we successfully prevent the aggregation of SQ-N in aqueous solutions, thus maintaining its excellent photothermal properties both in vitro and in vivo. Furthermore, the introduction of polyethylene glycol (PEG) significantly enhances cell permeability, which contributes to the remarkable therapeutic effect of POSS-SQ-DOX NPs. Our studies on the photothermal properties of POSS-SQ-DOX NPs demonstrate their high photothermal conversion efficiency (62.3%) and stability, confirming their suitability for use in mild photothermal therapy. A combination index value (CI = 0.72) verified the presence of a synergistic effect between these two treatments, indicating that POSS-SQ-DOX NPs exhibited significantly higher cell mortality (74.7%) and tumor inhibition rate (72.7%) compared to single chemotherapy and mild photothermal therapy. This observation highlights the synergistic therapeutic potential of POSS-SQ-DOX NPs. Furthermore, in vitro and in vivo toxicity tests suggest that the absence of cytotoxicity and excellent biocompatibility of POSS-SQ-DOX NPs provide a guarantee for clinical applications. Therefore, utilizing near-infrared light-triggering POSS-SQ-DOX NPs can serve as chemo-mild photothermal PTA, while functionalized POSS-SQ-DOX NPs hold great promise as a novel nanoplatform that may drive significant advancements in the field of chemo-mild photothermal therapy.
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Bai, Huiyuan, Quanhao Sun, Fei Kong, Haijiao Dong, Ming Ma, Fangzhou Liu, Chen Wang, Haiyan Xu, Ning Gu, and Yu Zhang. "Zwitterion-functionalized hollow mesoporous Prussian blue nanoparticles for targeted and synergetic chemo-photothermal treatment of acute myeloid leukemia." Journal of Materials Chemistry B 9, no. 26 (2021): 5245–54. http://dx.doi.org/10.1039/d1tb00548k.

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Illustration of HMPBs(DNR + AraC)@PEI-ZS-E5 for targeted and synergetic chemo-photothermal treatment of AML. The nanoplatform showed excellent photothermal effects, reduced protein adsorption and remarkable targeting/chemo/photothermal effects.
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43

Xue, Lei, Qing Shen, Tian Zhang, Yibin Fan, Xiaogang Xu, Jinjun Shao, Dongliang Yang, Wenli Zhao, Xiaochen Dong, and Xiaozhou Mou. "Fluorescence resonance energy transfer enhanced photothermal and photodynamic antibacterial therapy post a single injection." Materials Chemistry Frontiers 5, no. 16 (2021): 6061–70. http://dx.doi.org/10.1039/d1qm00631b.

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The constructed near-infrared photothermal nanoparticles (NDIA@PEG-Ce6/B NPs) can enhance the photothermal performance through the FRET effect and can achieve excellent photothermal and photodynamic antibacterial treatment post a single injection.
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Salazar, A., A. Sánchez-Lavega, J. M. Terrón, and M. Gateshki. "Aplicación de las técnicas fototérmicas al estudio de materiales." Boletín de la Sociedad Española de Cerámica y Vidrio 39, no. 4 (August 30, 2000): 584–88. http://dx.doi.org/10.3989/cyv.2000.v39.i4.825.

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Li Hao, 李浩, 周庆欣 Zhou Qingxin, 马生华 Ma Shenghua, and 王刚 Wang Gang. "光热膜的制备以及光芬顿催化性能的研究." Laser & Optoelectronics Progress 58, no. 19 (2021): 1916001. http://dx.doi.org/10.3788/lop202158.1916001.

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46

Li Yingjia, 李英甲, 倪开灶 Ni Kaizao, 王微微 Wang Weiwei, 刘世杰 Liu Shijie, 邵建达 Shao Jianda, 吴周令 Wu Zhouling, and 张龙 Zhang Long. "基于光热技术的氧化钇透明陶瓷缺陷特性研究." Chinese Journal of Lasers 48, no. 23 (2021): 2303001. http://dx.doi.org/10.3788/cjl202148.2303001.

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Ding Jiayu, 丁佳渝, and 彭斯颖 Peng Siying. "光热显微成像:一种免标记、高分辨的成像技术." Laser & Optoelectronics Progress 60, no. 22 (2023): 2200001. http://dx.doi.org/10.3788/lop231026.

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48

Li, Haifeng, Yu Yao, Hui Shi, Yanli Lei, Yan Huang, Kemin Wang, Xiaoxiao He, and Jianbo Liu. "A near-infrared light-responsive nanocomposite for photothermal release of H2S and suppression of cell viability." Journal of Materials Chemistry B 7, no. 39 (2019): 5992–97. http://dx.doi.org/10.1039/c9tb01611b.

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Photothermal nanoparticles and thermo-labile precursors are combined together as a near-infrared light triggered photothermal H2S-release platform for synchronous photothermal stimulation and gas release to suppress cell viability.
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Lee, Jung, Jo, Yang, Koh, and Hyun. "Near-Infrared Fluorescent Sorbitol Probe for Targeted Photothermal Cancer Therapy." Cancers 11, no. 9 (September 1, 2019): 1286. http://dx.doi.org/10.3390/cancers11091286.

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Abstract: Photothermal therapy (PTT) using a near-infrared (NIR) heptamethine cyanine fluorophore has emerged as an alternative strategy for targeted cancer therapy. NIR fluorophores showing a high molar extinction coefficient and low fluorescence quantum yield have considerable potential applications in photothermal cancer therapy. In this study, a bifunctional sorbitol–ZW800 conjugate was used as an advanced concept of photothermal therapeutic agents for in vivo cancer imaging and therapy owing to the high tumor targetability of the sorbitol moiety and excellent photothermal property of NIR heptamethine cyanine fluorophore. The sorbitol–ZW800 showed an excellent photothermal effect increased by 58.7 °C after NIR laser irradiation (1.1 W/cm2) for 5 min. The HT-29 tumors targeted by sorbitol–ZW800 showed a significant decrease in tumor volumes for 7 days after photothermal treatment. Therefore, combining the bifunctional sorbitol–ZW800 conjugate and NIR laser irradiation is an alternative way for targeted cancer therapy, and this approach holds great promise as a safe and highly efficient NIR photothermal agent for future clinical applications.
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Phan, Le Minh Tu, Thuy Anh Thu Vo, Thi Xoan Hoang, and Sungbo Cho. "Graphene Integrated Hydrogels Based Biomaterials in Photothermal Biomedicine." Nanomaterials 11, no. 4 (April 2, 2021): 906. http://dx.doi.org/10.3390/nano11040906.

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Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.
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