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Journal articles on the topic 'Phyllanthus niruri'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Faith Robert Owabhel and Abraham Sisein Eboh. "Antioxidant, chelating and HPLC quantification of phenols in extract of Phyllanthus niruri." World Journal of Advanced Pharmaceutical and Life Sciences 3, no. 1 (2022): 001–6. http://dx.doi.org/10.53346/wjapls.2022.3.1.0029.

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Phyllanthus niruriis a known medicinal plant. The leaves of Phyllanthus niruri were evaluated for antioxidant activity utilizing different methods and the quantification of phenols and flavonoid using HPLC (High Performance Liquid Chromatography). The leaves of Phyllanthus niruri were harvested, shade dried, grounded and extracted with methanol. The extract was subjected to total antioxidant capacity, DPPH radical scavenging, nitric oxide (NO) scavenging, ferrous chelation and HPLC quantification of phenolics and flavonoids. The result showed total antioxidant capacity of 13.04 ±0.08 mgAAE/g.

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KH, Tri Desiana, Achmad Sudirman, and Devi Eka Juniarti. "Daya Antibakteri EkstrakMeniran (Phyllanthus niruri linn) Terhadap BakteriEnterococcus faecalis (Antibacterial Activity Of Phyllanthus niruri linn Extract Against Enterococcus faecalis Bacteria)." Conservative Dentistry Journal 6, no. 2 (2016): 99. http://dx.doi.org/10.20473/cdj.v6i2.2016.99-104.

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Background. Enterococcus faecalis is an anaerobic facultative gram-positive bacteria which contribute to the failure of root canal treatment with the number of prevalence 24% to 77%. At the preparation stage, a material for irrigation which has antibacterial activity to Enterococcus faecalis is needed. Phyllantus niruri linn is one of herbal medicament which is potential as antibacterial agent as it contains active antibacterial chemical-compound. Purpose. The purpose of the study is to identify Minimum Inhibitory Concentration and Minimum Bactericidal Concentrationof Phyllantus niruri linn ag

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Adrianto, Albertus Ari, Ignatius Riwanto, Udadi Sadhana, et al. "Enhancing colorectal cancer treatment efficacy: A comprehensive investigation into the synergistic potential of Phyllanthus niruri Linn and capecitabine in targeting cancer stem cells." Bali Medical Journal 13, no. 3 (2024): 1180–86. https://doi.org/10.15562/bmj.v13i3.5208.

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Introduction: Colorectal cancer (CRC) prevalence is rising globally with significant mortality rates. Cancer stem cells (CRC-SC) resist chemotherapy, marked by CD133 and CD44. Immune system involvement and immunosuppression in chronic inflammation impact CRC progression. CD18 and CD8 are crucial in T cell migration and activation. Capecitabine is a common chemotherapy for CRC. Phyllantus niruri Linn exhibits immunomodulatory effects, inducing apoptosis and inhibiting proliferation in colon cancer cell lines. The study aims to assess the effectiveness and safety of combination therapy, correlat

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Irawan, Adinda Riezki, Emy Koestanti Sabdoningrum, Sri Hidanah, Sri Chusniati, Sri Pantja Madyawati, and Benjamin Christoffel Tehupuring. "PEMBERIAN EKSTRAK MENIRAN (Phyllanthus niruri Linn) TERHADAP GAMBARAN HISTOPATOLOGI INFUNDIBULUM AYAM PETELUR YANG DIINFEKSI Escherichia coli." Journal of Basic Medical Veterinary 8, no. 1 (2020): 53. http://dx.doi.org/10.20473/.v8i1.19992.

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The purpose of this research aimed to prove the effect of meniran extract (Phyllanthus niruri Linn) on layer hen infected with Escherichia coli to reduce inflammation and congestion on infundibulum histopathological view. This research used 20 samples of layer hen. The treatment in this research was P0- (not infected with Esherichia coli and did not treated with meniran(Phyllanthus niruri Linn)), P0+ (infected with Escherichia coli and did not treated with meniran(Phyllanthus niruri Linn)), P1 (infected with Escherichia coli and treated with 10% meniran extract (Phyllanthus niruri Linn)), P2 (

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5

Dan Madi Hartono, Heru Febryantono, Siswanto, Purnama Edy Santosa,. "PENGARUH PEMBERIAN DOSIS EKSTRAK MENIRAN (Phyllanthus niruri L) TERHADAP TITER ANTIBODI NEWCASTLE DISEASE DAN AVIAN INFLUENZA PADA BROILER JANTAN." Jurnal Riset dan Inovasi Peternakan (Journal of Research and Innovation of Animals) 4, no. 1 (2020): 52–58. http://dx.doi.org/10.23960/jrip.2020.4.1.52-58.

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This study was intended to know the effect of meniran (Phyllanthus niruri L) extract as an immunomodulator against avian influenza (AI) and newcastle disease (ND) antibody titers in male broilers, which was conducted in April 2019 to May 2019 at the Integrated Field Laboratory, Faculty of Agriculture, University of Lampung. Analysis of antibody titers was carried out at the Lampung Veterinary Virology Laboratory in Lampung. This study used Completely Randomized Design (CRD) with four treatments and five replications, those were drink water without Phyllanthus nirurilinn extract (P0), drink wat

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Rahmahani, Jola, Rahaju Ernawati, and Didik Handijatno. "EFFECT OF PHYLLANTHUS NIRURI L. EXTRACT AS IMMUNOSTIMULATOR ON CHICKEN VACCINATED BY NEWCASTLE DISEASE." Jurnal Veteriner 22, no. 1 (2021): 125–32. http://dx.doi.org/10.19087/jveteriner.2021.22.1.125.

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Newcastle Disease or tetelo is one of main problem in poultry Industry in Indonesia. Prevention such as biosecurity control and routin vaccination program have been conducted to overcome this problem, but they have not given any great impact. Phyllanthus Niruri L. or meniran is well known as immunostimulatory. This research was aimed to reveal effect of Phyllanthus Niruri L. extract on chicken vaccinated with live vaccine LaSota. Administration of Phyllanthus Niruri L. extract was conducted on three different time which were 7 days before vaccination, 1 days after vaccination, and 3 days befor

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7

Fabi Aisah Setiorini, Hari Suprapto, Sudarno,. "Efektifitas Ekstrak Tanaman Meniran (Phyllanthus niruri) Sebagai Antibakteri Edwardsiella tarda Secara In Vitro [Effectivity Of Meniran (Phyllanthus niruri) Extract as Edwardsiella tarda Antibacterial According In Vitro]." Jurnal Ilmiah Perikanan dan Kelautan 3, no. 1 (2019): 103. http://dx.doi.org/10.20473/jipk.v3i1.11631.

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AbstractMedicinal plants proven to effectively cope with bacterial diseases one of which is the plant meniran (Phyllanthus niruri). Phyllanthus niruri can act as an antibacterial because it has an antibacterial ingredient content of flavonoids, alkaloids, phenols, and tannins. This shows that plants can be used as an antibacterial Phyllanthus niruri of E.tarda. The purpose of this study was to determine the ability of the antibacterial of Phyllanthus niruri extracts and to find out the best concentration of Phyllanthus niruri extracts as antibacterial E.tarda according in vitro. The experiment

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8

Hikmah, Uzulul, and Asih Triastuti. "Phyllanthus niruri (Meniran) Sebagai Imunomodulator: Mekanisme aksi dan senyawa bioaktif." Jurnal Ilmiah Farmasi 18, no. 2 (2022): 205–18. http://dx.doi.org/10.20885/jif.vol18.iss2.art19.

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Latar belakang: Phyllanthus niruri merupakan tanaman obat yang memiliki beberapa aktivitas farmakologi seperti antimikroba, antioksidan, antikanker, antiinflamasi, antiplasmodium, antivirus, diuretik, hepatoprotektif, dan sebagai imunomodulator. Tujuan: Melakukan tinjauan analisis mengenai efektivitas P. niruri) sebagai imunomodulator pada uji preklinis maupun uji klinis. Hasil: Kandungan kimia P. niruri seperti flavonoid, lignan, terpenoid, dan alkaloid berperan penting pada aktivitas farmakologi P. niruri sebagai imunomodulator. Uji in silico menunjukkan potensi P. niruri sebagai

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L, Ima Arum, Purwanto AP, and Henna Rya. "PHYLLANTHUS NIRURI L TERHADAP IMUNITAS SELULER TIKUS." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 18, no. 1 (2016): 35. http://dx.doi.org/10.24293/ijcpml.v18i1.358.

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Typhoid fever is a problem in the developing country. Phyllanthus niruri L (meniran) is a traditional plant that can be used as an immunomodulator on cellular or humeral immunity. By giving Phyllanthus niruri L extract to patient who suffers typhoid fever can increase cellular immunity responses in intracellular bacteria infection (S.typhimurium).This research was an experimental study using the post test-only control group design to proof of the effects of Phyllanthus niruri L on cellular immunity balb/c infected by salmonella typhimurium. The samples were taken from thirty male Balb/c mice w

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Ibrahim, Sugeng, Nurul Hidayah, Fauziah Novita Putri Rifai, and Dede Ginanto. "Cooperative Impact of Curcuma longa and Phyllanthus niruri Extracts on Cytotoxicity in HCT-116 Cells." International Journal of Cell and Biomedical Science 2, no. 5 (2024): 152–59. https://doi.org/10.59278/cbs.v2i5.36.

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Background: The combination of herbal extracts has the potential to enhance cytotoxic effects against cancer cells. This study explores the combined cytotoxic effects of Curcuma longa and Phyllanthus niruri extracts on HCT-116 colorectal cancer cells. Objective: To assess the cytotoxic effects of Curcuma longa and Phyllanthus niruri extracts when used in combination and to determine the most effective ratio for inhibiting HCT-116 cell growth. Methods: HCT-116 cells were treated for 24 hours with varying concentrations of Curcuma longa and Phyllanthus niruri extracts based on the IC50 values of

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Wahyuni, Wahyuni, Ahmad Irsyad Aliah, and Erni Semboh. "Formulasi Gel Dan Uji Efektivitas Ekstrak Etanol Daun Meniran (Phyllanthus Niruri L.) Terhadap Penyembuhan Luka Sayat Pada Kelinci Jantan (Oryctolagus Cuniculus)." Media Kesehatan Politeknik Kesehatan Makassar 16, no. 1 (2021): 76. http://dx.doi.org/10.32382/medkes.v16i1.1798.

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Telah dilakukan penelitian tentang Formulasi Gel Dan Uji Efektivitas Ekstrak Etanol Daun Meniran (Phyllanthus niruri L.) Terhadap Penyembuhan Luka Insisi Pada Kelinci Jantan (Orygtolagus cuniculus). Daun meniran (Phyllanthus niruri L.) memiliki kandungan saponin, flavonoid. Daun meniran (Phyllanthus niruri L.) diekstraksi dengan metode meserasi menggunakan cairan penyari etanol 70%. Perlakuan dibagi 5 kelompok yaitu kontrol negatif (Gel basis tanpa ekstrak) dan control positif (Povidone Iodine), konsentrasi 3%, konsentrasi 6%, dan konsentrasi 9%. Gel dioileskan pada kulit kelinci (sebanyak 3-4

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Novianto, Agil, Arief Nurrochmad, and Ika Puspitasari. "Aktivitas Hepatoprotektif Ekstrak Kunyit (Curcuma domestica Val.) dan Ekstrak Meniran (Phyllantus niruri Linn.) Pada Tikus yang Diinduksi Parasetamol Kajian Histopatologi Liver." Jurnal Farmasi (Journal of Pharmacy) 3, no. 1 (2019): 10. http://dx.doi.org/10.37013/jf.v3i1.21.

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Curcuma domestica dan Phyllanthus niruri adalah dua tanaman yang telah terbukti memiliki efek hepatoprotektif. Penelitian ini dilakukan untuk mengetahui studi mekanisme hepatoprotektif dari kombinasi ekstrak Curcuma domestica dan Phyllanthus niruri dengan hewan yang diinduksi parasetamol. Hewan dibagi menjadi 8 kelompok secara acak masingmasing 5 tikus. Kelompok yang normal adalah aquadest, kelompok negatif (Parasetamol) adalah CMC Na 0,5%, kelompok positif diberi silimarin dengan dosis 100 mg / kg kelompok Curcuma domestica dengan dosis 100 mg/kg, kelompok Phyllanthus niruri dengan 200 mg/kg

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13

Anang Kurniawan, Alya Afriana Syahrani, Annatsa Yolantiara Mahanani, Desianti Cahya Nugraheni, Maulana Rahmadani, and Liss Dyah Dewi Arini. "Pengaruh Ekstrak Pemberian Tumbuhan Meniran terhadap Kesehatan." Jurnal Mahasiswa Ilmu Kesehatan 3, no. 1 (2024): 39–46. https://doi.org/10.59841/jumkes.v3i1.1993.

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Meniran Meniran (Phyllanthus niruri L.) contains bioactive compounds that are able to inhibit bacterial growth (antibacterial) and kill bacteria. This research aims to determine the effect of the concentration of extract Phyllanthus niruri L. and the effective concentration of Phyllanthus niruri L. which can inhibit the growth of Staphylococcus aureus and Escherichia coli bacteria. The test bacteria used were Staphylococcus aureus and Escherichia coli. This research was experimental using a completely randomized design (CRD) with 11 treatments consisting of extract concentrations of 0%, 10%, 2

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Sarisetyaningtyas, Patria Vittarina, Sri Rezeki Hadinegoro, and Zakiudin Munasir. "Randomized controlled trial of Phyllanthus niruri Linn extract." Paediatrica Indonesiana 46, no. 2 (2016): 77. http://dx.doi.org/10.14238/pi46.2.2006.77-81.

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Background Clinical benefits of antiviral treatment in childrenexperience varicella without complications, remains controversial.Phyllanthus niruri Linn extract as a natural medicine is used toincrease cellular and humoral immunity.Objective To determine the efficacy and safety of Phyllanthusniruri Linn extract in the treatment of varicella in children comparedto placebo.Methods This was a double-blind randomized controlled trial onchildren ages 2-14 years who experienced varicella without com-plications. Subjects were randomly assigned to receive eitherPhyllanthus niruri Linn extract syrup (5

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Chimsook, Thitiphan. "Bioactivities of Mimosa pudica and Phyllanthus niruri Crude Extracts Collected from the Locality of Chaiyaphum, Thailand." Advanced Materials Research 1044-1045 (October 2014): 12–15. http://dx.doi.org/10.4028/www.scientific.net/amr.1044-1045.12.

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Mimosa pudica and Phyllanthus niruri were used as the traditional medicines in Thailand. Both plants were very useful for various pharmacological and biological activities. In the present study, the bioactivities of Mimosa pudica and Phyllanthus niruri extracts were investigated. The amounts of total phenolic compounds were analyzed using gallic acid as standard compound and the antioxidant activities were evaluated using ABTS assay. The phenolic content of Mimosa pudica extracts revealed that AEE1 contained the maximum phenolic content and that of Phyllanthus niruri extracts exhibited the sam

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Daniel, Juth, Buba Mohammed, and A. Ahmed. "Phytochemical Screening of the Leaf Extract of Phylantus niruri." NEWPORT INTERNATIONAL JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES 6, no. 2 (2025): 59–63. https://doi.org/10.59298/nijses/2025/62.596300.

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The purpose of this research was to investigate the phytochemical profile of Phyllanthus niruri leaf extract, which has long been utilised as an effective cure for a variety of diseases. Fresh Phyllanthus niruri leaves were obtained from Yola city and sent to the Department of Science Laboratory Technology Federal Polytechnic, Mubi, for identification. The phytochemicals were extracted and analysed using the solvent extraction technique, which employed methanol as the solvent. The results showed the presence of carbohydrates, alkaloids, tannins, steroids, flavonoids, and anthraquinone, but no

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Ferraz, Renato Ribeiro Nogueira, Eduardo de Andrade Pinguer, Valdemar Soares de Melo Júnior, et al. "Efeitos Medicinais Do Extrato De Phyllanthus Niruri (Chá De Quebra-Pedra): Síntese De Evidências." Journal of Medical Residency Review 1, no. 1 (2022): e023. http://dx.doi.org/10.37497/jmrreview.v1i1.23.

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Introdução: O gênero Phyllanthus tem sido utilizado na medicina tradicional por sua ampla gama de atividades farmacológicas, como antimicrobiana, antioxidante, anticancerígena, anti-inflamatória, antiplasmódica, antiviral, diurética e hepatoprotetora. Objetivo: Revisar a literatura especializada acerca dos efeitos medicinais do extrato de Phyllanthus niruri. Método: As bases de dados escolhidas para seleção dos trabalhos foram a PUBMED, a LILACS e a SCIELO, utilizando a seguinte estratégia de busca: “Phyllanthus niruri”. Resultados: Foram identificados 10 trabalhos que preenc

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Widyawaty, Eka Deviany. "Pengaruh Meniran Dosis Bertingkat Terhadap Ekspresi IGF-1 Dan Ketebalan Endometrium Pada Mencit Betina Model Endometriosis." Jurnal Biosains Pascasarjana 20, no. 1 (2018): 9. http://dx.doi.org/10.20473/jbp.v20i1.2018.9-21.

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Abstrak Endometriosis menyebabkan 10-15% dari nyeri panggul dan infertilitas pada wanita usia reproduksi. Walaupun endometriosis dapat mempengaruhi infertilitas, tetapi mekanisme dari hal tersebut sampai sekarang masih belum diketahui secara pasti. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol herba meniran (Phyllanthus niruri L.) dosis bertingkat terhadap ekspresi Igf-1 dan ketebalan endometrium pada mencit (Mus musculus) betina model endometriosis. Sampel penelitian ini adalah mencit (Mus Musculus) betina model endometriosis. Pada hari ke-15, Kelompok Kontrol (K

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Kotaru, Manvitha, and Sridevi Korimelli. "Evaluation of Anti-Diabetic Activity of Silver Nanoparticles Synthesized from Ethanolic Extract of Phyllanthus niruri on Wistar Rats." Journal of Drug Delivery and Therapeutics 13, no. 6 (2023): 83–88. http://dx.doi.org/10.22270/jddt.v13i6.6098.

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Diabetes is a metabolic disorder characterized by hyperglycemia resulting from either the deficiency in insulin secretion or the action of insulin Diabetes can affect numerous different organ systems in the body and, over time, can lead to serious complications. Complications are microvascular or macrovascular. To evaluate the anti-diabetic effect of Phyllanthus niruri silver nano-particles. Streptozotocin (STZ) of 50mg/kg is used to induce diabetes in wistar rats. The wistar rats were distributed to six different groups. Group-I represented as Control; Group-II represented as diabetic control

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Harmoni, Dewi Natalia Sri, Lalu Mariawan Alfarizi, and Hamita Dewi. "Uji Aktivitas Antibakteri Ekstrak Etanol Daun Meniran (Phyllanthus Niruri L) Terhadap Bakteri Stapylococcus Epidermidis." JURNAL KESEHATAN TROPIS INDONESIA 3, no. 1 (2025): 35–42. https://doi.org/10.63265/jkti.v3i1.70.

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Jerawat merupakan salah satu penyakit kulit yang banyak dikeluhkan terutama pada remaja karena dapat merusak kepercayaan diri. Penyakit kulit tersebut disebabkan karena peradangan menahun folikel pilosebasea. Jerawat disebabkan oleh bakteri Staphylococcus epidermidis. Salah satu tanaman yang memiliki khasiat sebagai antibakteri yaitu tumbuhan meniran (Phyllanthus niruri L). Dalam penelitian ini bertujuan Untuk mengetahui pengaruh konsentrasi efektivitas ekstrak etanol daun meniran (Phyllanthus niruri L) terhadap daya hambat bakteri Staphylococcus epidermidis. Penelitian ini merupakan penelitia

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Safriyana, Baiq Ihda Nanda, Agriana Rosmalina Hidayati, and Iman Surya Pratama. "Aktivitas antelmintik ekstrak herba meniran (Phyllanthus niruri) terhadap Paramphistomum spp." Sasambo Journal of Pharmacy 5, no. 2 (2024): 91–96. http://dx.doi.org/10.29303/sjp.v5i2.245.

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Phyllanthus niruri is traditionally used to treat intestinal worms. The content of flavonoids in Phyllanthus niruri has the potential as an anthelmintic. The aims of study are to identify flavonoid compounds of the ethanolic extract of Phyllanthus niruri and determine the anthelmintic activity against Paramphistomum spp. Paramphistomum spp. grouped into positive control (Albendazole 10% w/v), negative control (CMC-Na 0.5% w/v), ethanolic extract of Phyllanthus niruri 1.25%, 2.5%, and 5% w/v. For 5 hours, the time and quantity of dead worms were counted every 15 minutes. The average time of dea

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Tiara, Nastiti Sari, and Suprapto. "Optimization of Gelatin and Pectin Combination as a Gelling Agent in the Formulation of Flawless Jelly Preparations with Ethanol Extracts of Meniran (Phyllanthus Niruri) and Kelor (Moringa Oleifera)." International Journal of Medical Science and Clinical Research Studies 05, no. 02 (2025): 279–85. https://doi.org/10.5281/zenodo.14864225.

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Formulating the Jelly Flawless preparation using extracts of meniran (<em>Phyllanthus niruri</em>) and Moringa (<em>Moringa oleifera)</em> which are rich in antioxidants. Antioxidants have an important role in the body by protecting cells from damage caused by free radicals. The Jelly Flawless formulation with ethanolic extracts of meniran (<em>Phyllanthus niruri</em>) and kelor (<em>Moringa oleifera),</em> combined with gelatin and pectin, affects the hardness test, showing no significant hardness in the fourth formulation. It contains positive secondary metabolites such as tannins,

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Chowdry, Shoket Mahmood, Atal Bihari Trivedi, and Raman Sharma. "CLINICAL EVALUATION OF BHUMYAMALAKI GHANA VATI IN THE MANAGEMENT OF KAMALA WITH SPECIAL REFERENCE TO HEPATITIS B." International Ayurvedic Medical Journal 9, no. 5 (2021): 952–59. http://dx.doi.org/10.46607/iamj0209052021.

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Kamala is a Pittaja Nanatmaja Vyadi and Rakta Pradoshaja Vyadi. The main Dusya is Rakta, at the same time it is Pitta predominant disease. In the present era, Rakta Dhatu (blood) is given utmost importance as the diseases pertaining to Rakta is more in incidence. Ayurveda, an ancient system of medicine has historically been highly proficient and has been treating liver disorders for centuries and drug toxicity tends to be lower than the conven- tional medicine. The drug Bhumyamalaki (Phyllanthus Niruri) is explained in Bhava Prakash Nighantu under Guduchyaidi Varga for the treatment of Kamala.

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Pahmi, Khairil, and M. Sidratullah. "Effect of Leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in sodium chloride -induced fibrotic rats." Bioscientia Medicina : Journal of Biomedicine and Translational Research 5, no. 3 (2021): 263–67. http://dx.doi.org/10.32539/bsm.v5i3.187.

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Background. Phyllanthus niruri (local name : meniran) extract is utilized in treating kidney and uterus disease. Effects of ethanol extract of P. niruri on kidney and uterus of 2% NaCl triggered fibrotic rats had been studied. Aim of Study. Aim of this study to explore the effect of leafflower (Phyllanthus niruri Linn.) treatment on kidney and uterus in 2% NaCl - induced fibrotic rats. Methods. Wistar rats were challenged with 2% NaCl in drinking water to induce fibrotic kidney and uterus. Phyllanthus niruri extract (200 mg/kg) was given orally for 4 weeks. Matrix extracellular abu

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Leão, Maria Fernanda de Moura, Camila Martins Güez, Jonathaline Apollo Duarte, et al. "AVALIAÇÃO DOS EFEITOS ANTI-GENOTÓXICOS DE Phyllanthus niruri (EUPHORBIACEAE) EM LEUCÓCITOS HUMANOS EXPOSTOS A AGENTE AGRESSOR." Saúde (Santa Maria) 43, no. 1 (2017): 133. http://dx.doi.org/10.5902/2236583423267.

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Em muitos lugares ao redor do mundo as plantas medicinais ou parte delas são usadas de forma paliativa ou curativa para o tratamento de diversas enfermidades, devido a dificuldade ao acesso a tratamentos convencionais. Nesse contexto, preparações a base de Phyllanthus niruri, que é popularmente conhecida como “Quebra-Pedra” ou “Erva-Pombinha” tem sido muito usadas no tratamento de diversas enfermidades como hipertensão, diabetes, cálculos renais, entre outros. O presente estudo visou avaliar a capacidade anti-genotóxica do extrato hidroalcoólico de Phyllanthus niruri, através da análise fitoqu

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Pelumi, ADANIGBO, Alfred JIDE, and Remi OSANYINLUSI. "Comparative Study of the Nutritional and Anti Nutritional Composition of Phyllantus niruri and Carica papaya." Pharmaceutical and Chemical Journal 8, no. 3 (2021): 8–12. https://doi.org/10.5281/zenodo.13961601.

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The leaves of <em>Phyllanthus niruri</em> and <em>Carica papaya </em>were dried and ground for antimicrobial and physiological properties. The data generated were subjected to basic statistical analysis with both samples having low levels of oxalate (1.05 mg/100g) for <em>Phyllanthus niruri</em> and (1.06mg/100g) for <em>Carica papaya</em>, but high in phytate, glycoside, and steroids. The proximate analysis revealed that the moisture content was (9.2±0.01 and 7.54±0.01) and the percentage ash content was (2.50±0.15 and 2.56±0.0015) respectively, which indicates tha

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Aulia Debby Pelu, Cut Bidara Panita Umar, and Nahdiyanti Ias. "UJI DAYA HAMBAT REBUSAN TANAMAN MENIRAN (Phyllanthus niruri L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli DENGAN METODE DIFUSI AGAR." Jurnal Kesehatan Amanah 5, no. 1 (2021): 01–08. http://dx.doi.org/10.57214/jka.v5i1.136.

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Meniran ( Phyllanthus niruri L.) is one of the plants used by the community for treatment. this plants is believed to have properties to treat diseases, one of which is the treatment of diarrhea. Porpose : This study was to identify the chemical content of meniran ( Phyllanthus niruri L.) stew, to determine the inhibition of the growht of Escherichia coli bacteria from each concenration of meniran (Phyllanthus niruri L.) stew. Methods :This study used an experimental desigh with concentration of 20%, 40%, 80% and 100%. Results : This study showed that meniran stew had chemical compounds, namel

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Pahmi, Khairil, Lale Syifaun Nufus, and Dahlia Andayani. "Influence of Phyllanthus niruri Linn. Extract Therapy on Renal and Uterus in 2% NaCl -induced Fibrotic Scarring Rodents." Jurnal Ilmu Kesehatan dan Farmasi 11, no. 1 (2023): 41–43. http://dx.doi.org/10.51673/jikf.v11i1.1747.

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Background Phyllanthus niruri (english name : leafflower) extract is used in therapy of renal and uterus fibrotic scarring disease. Influence of alcohol extract of P. niruri on renal and uterus of 2% NaCl- induced fibrotic scarring rodents had been researched. Aim of Study Purpose of this research to study the influence of leafflower (Phyllanthus niruri Linn.) therapy on renal and uterus in 2% NaCl - induced fibrotic scarring rodents. Methods Wistar rodents were stimulated with 2% NaCl in drinking water to induce fibrotic scarring renal and uterus. Phyllanthus nir

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Nisa, Arofatin. "POTENSI PEMBERIAN EKSTRAK MENIRAN (Phyllanthus Niruri L) TERHADAP PENINGKATAN RESPONS IMU HUMORAL PADA MENCIT YANG DI INFEKSI Salmonella enterica serovar Typhi." Jurnal Biosains Pascasarjana 17, no. 2 (2015): 82. http://dx.doi.org/10.20473/jbp.v17i2.2015.82-89.

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Abstrak Salah satu tanaman yang memiliki kandungan imunomodulator yaitu meniran (Phyllanthus niruri L). Beberapa golongan zat utama yang terkandung dalam meniran (Phyllanthus niruri L.) adalah lignan, tanin, polifenol, alkaloid, flavonoid, terpenoid dan steroid .Terhadap respon imun spesifik pemberian ekstrak meniran mampu meningkatkan proliferasi sel limfosit T, meningkatkan sekresi TNFα, IFNγ, dan IL-4 serta menurunkan sekresi IL-2 dan IL-10. Terhadap imunitas humoral, ekstrak meniran ini dapat meningkatkan produksi imunoglobulin M (IgM) serta imunoglobulin G (IgG) . Untuk mengetahui potensi

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Sugumar R, Saravana D, Pavithra N, Suresh Raj V, Sekar Babu M, and Vijey Aanandhi M. "Investigation on phytochemical composition, anti-oxidant and anticancer properties of methanolic extract of Phyllanthus niruri schumach & thonn. And protein modelling and drug docking." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7937–43. http://dx.doi.org/10.26452/ijrps.v11i4.4704.

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The study aims to investigate the Phytochemical Composition, Anti-oxidant and Anticancer properties of methanolic extract of Phyllanthus niruri Schumach & Thonn And the Protein Modelling and drug docking. The research deals with the methanolic extraction and phytochemical screening, determination of total phenolic and flavonoids contents and anti-oxidant assay. By performing GC-MS characterisation, various active metabolites are analysed. Thin-layer chromatography profiling of the Phyllanthus niruri methanolic extract was performed. The IC50 of the Phyllanthus niruri methanolic extract aga

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Hatur Rahman, Mufti. "Uji Aktivitas Antibakteri Fraksi n-heksan dari Ekstrak Daun Meniran (phyllanthus niruri L.) Terhadap Pertumbuhan Bakteri salmonella sp." SAINTIFIK 7, no. 2 (2021): 96–104. http://dx.doi.org/10.31605/saintifik.v7i2.331.

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Meniran (Phyllanthus niruri L.) adalah tumbuhan Euphorbiaceae yang banyak tumbuh liar pada daerah tropis yang mengandung senyawa bioaktif flavonoid, filantin dan hipofilantin yang mampu menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri fraksi N-heksan dari ekstrak daun meniran terhadap pertumbuhan bakteri Salmonella sp. Penelitian ini adalah penelitian eksperimen pengujian efek antibakteri dengan metode ekstraksi meniran (Phyllanthus niruri L.) menggunakan pelarut non polar berupa n-heksan dengan variasi konsentrasi 0.1%, 0,5%, 1% dan 5%. Uji antim

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I, Aminathul Nifa, Dinesh Dhamodhar M, D. Prabu, et al. "Systematic Review of Anti-Inflammatory Properties of Phyllanthus Niruri." International Journal of Innovative Science and Research Technology 7, no. 8 (2022): 1860–63. https://doi.org/10.5281/zenodo.7110817.

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The study aims to assess the anti-inflammatory properties of Phyllanthus niruri.  Materials and Method A systematic review was performed using PubMed, scholar, Wiley, Cochrane, Scopus and science direct. Of 213 articles from various sources,180 were screened, and five were related to the research topic. The review was reported according to the systematic review guidelines.  Result Five articles were included, and they were all compared to find the anti- inflammatory properties of Phyllanthus niruri. No meta-analysis was performed during the clinical heterogeneity.  Conclusion With a compara

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Susanti, R., Farikhatun Nur Fitriya, K. Kristamtini, and Didik Huswo Utomo. "Anti-Inflammatory Effect of <i>Phyllanthus niruri</i>: A Meta-Analysis." Biosaintifika: Journal of Biology & Biology Education 16, no. 2 (2024): 332–41. http://dx.doi.org/10.15294/biosaintifika.v16i2.10823.

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Many studies report on the role of Phyllanthus niruri as an anti-inflammatory and there are variations in the results in every research, so a meta-analysis study is needed to obtain accurate results. This study aims to conduct a meta-analysis of the effect of Phyllanthus niruri as an anti-inflammatory. This study uses a meta-analysis research design with data collection from 12 databases. The screening process was carried out according to PRISMA, then analyzed using Comprehensive Meta-Analysis Version 3 (CMA3). Funnel plot and Egger’s test were used as methods to measure publication bias. The

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Marhaeny, Honey Dzikri, Aty Widyawaruyanti, Tri Widiandani, Achmad Fuad Hafid, and Tutik Sri Wahyuni. "Phyllanthin and hypophyllanthin, the isolated compounds of Phyllanthus niruri inhibit protein receptor of corona virus (COVID-19) through in silico approach." Journal of Basic and Clinical Physiology and Pharmacology 32, no. 4 (2021): 809–15. http://dx.doi.org/10.1515/jbcpp-2020-0473.

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Abstract Objectives Phyllanthus niruri has been known as an immunomodulator and also reported to possess an antiviral activity against several RNA viruses, such as hepatitis B virus and hepatitis C virus by inhibiting viral entry and replication. Since the current situation of Coronavirus Disease 2019 (COVID-19) which infected among the world and caused severe disease and high morbidity, it urgently needed to find new agents against COVID-19. Therefore, in silico screening against COVID-19 receptors is carried out as an initial stage of drug discovery by evaluating the activity of phyllanthin

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Nigam, R., and R. Arnold. "Qualitative and Quantitative Phytochemical Screening and Chemical Fingerprint Analysis of Herbal Plant Phyllanthus niruri using HPTLC." Journal of Scientific Research 13, no. 2 (2021): 623–33. http://dx.doi.org/10.3329/jsr.v13i2.50391.

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 This study focused to develop the fingerprint profile of Phyllanthus niruri through high performance thin layer chromatography. Various solvent extracts such as ethanol and water were prepared and phytochemical screening was made using standard procedures. The preliminary phytochemical analysis of two extracts of the plant showed the presence of secondary metabolites viz., alkaloids, triterpenoids, proteins, amino acids, flavonoids and steroids. The total flavonoid contents of leaves were significantly higher than those revealed in stem and root. The total phenolic contents of Phyllanth

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K., Prabakaran. "PHYTOCHEMICAL PROFILE AND LARVICIDAL ACTIVITY OF PHYLLANTHUS NIRURI LEAVES EXTRACT AGAINST MOSQUITO LARVAE." International Journal of Zoology and Applied Biosciences 3, no. 2 (2018): 168–73. https://doi.org/10.5281/zenodo.1314026.

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Phytochemical analysis and mosquito larvicidal effect of leaf extracts of Phyllanthus niruri was studied against malaria, filaria and dengue vectors of Anopheles stephensi, Culex quinquefasciatus and Aedes aegypti. The phytochemical analysis was assessed by phytochemical screening tests. The larvicidal activity of Phyllanthus niruri leaves extract was tested against mosquito larvae following the WHO protocol. The mortality was observed at 24h after treatment and the data were subjected to probit analysis to determine the lethal concentration (LC50 and LC90) to kill 50 and 90 percent of the tre

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Rusmana, Djaja, Roro Wahyudianingsih, Mariska Elisabeth, Balqis Balqis, Maesaroh Maesaroh, and Wahyu Widowati. "Antioxidant Activity of Phyllanthus niruri Extract, Rutin and Quercetin." Indonesian Biomedical Journal 9, no. 2 (2017): 84. http://dx.doi.org/10.18585/inabj.v9i2.281.

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BACKGROUND: Normal metabolism of oxygen and exogenous factors constantly generate free radicals which could be harmful to the human body. Human need antioxidants to provide protection against free radicals, thus plants are a good source of natural antioxidants. Phyllanthus niruri (P. niruri) has been known to possess several medicinal properties and contain numerous active phytochemical. In this research, we conducted phytochemical screening and antioxidant assay of P. niruri extract along with the compounds rutin and quercetin, which are flavonoids possessing medicinal properties. This study

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Inglis, Peter, Lorena Mata, Marcos da Silva, et al. "DNA Barcoding for the Identification of Phyllanthus Taxa Used Medicinally in Brazil." Planta Medica 84, no. 17 (2018): 1300–1310. http://dx.doi.org/10.1055/a-0644-2688.

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AbstractPlants of the genus Phyllanthus, principally Phyllanthus amarus, Phyllanthus urinaria, Phyllanthus niruri, and Phyllanthus tenellus, are used in Brazilian folk medicine to treat kidney stones as well as other ailments, where the latter two species are listed in the Brazilian Pharmacopeia as quebra-pedra (stone-breaker). However, only P. niruri has been shown to be effective in a clinical setting. Nuclear ribosomal internal transcribed spacer (ITS1 – 5.8S rRNA-ITS2), internal transcribed spacer 2, and chloroplasts rbcL, matK, psbA-trnH, trnL, and trnL-trnF were screened for their potent

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Sumiati, Risma Laila, Farhan Baehaki, Nurdin Nurdin, and Suyarta Efrida Pakpahan. "Ekstrak Daun Meniran (Phyllanthus niruri L.) : Bagaimana Pengaruhnya Terhadap Jumlah Trombosit di Dalam Darah?" Stannum : Jurnal Sains dan Terapan Kimia 6, no. 1 (2024): 48–56. http://dx.doi.org/10.33019/jstk.v6i1.4401.

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Thrombocytopenia is a condition in which the platelet count is below normal (<150,000-450,000 cells/mm3). Until now, the treatment of thrombocytopenia has not yet found a specific drug and there are side effects from chemical treatment, so alternative solutions are needed, one of which is the use of meniran leaves (Phyllanthus niruri L.). The meniran plant is a wild plant that is often found in the wild, on the streets, as well as vacant land so that people can easily get these plants. The aim of this research was to determine the effect of meniran leaf extract (Phyllanthus niruri L.) on th

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Морозова, Ю. А., Д. С. Дергачев та М. А. Суботялов. "Противовирусная активность Phyllanthus niruri (Phyllanthaceae)". Растительные ресурсы 55, № 4 (2019): 439–48. http://dx.doi.org/10.1134/s0033994619040071.

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Suraya, Azal Anis, Azizah Misran, and Mansor Hakiman. "The Efficient and Easy Micropropagation Protocol of Phyllanthus niruri." Plants 10, no. 10 (2021): 2141. http://dx.doi.org/10.3390/plants10102141.

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Phyllanthus niruri (P. niruri) or Dukung Anak is a herbal plant in the Phyllanthaceae family that has been used traditionally to treat various ailments such as diabetes, jaundice, flu and cough. P. niruri contains numerous medicinal benefits such as anti-tumor and anti-carcinogenic properties and a remedy for hepatitis B viral infection. Due to its beneficial properties, P. niruri is overharvested and wild plants become scarce. This study was conducted to develop an appropriate in vitro culture protocol for the mass production of P. niruri. An aseptic culture of P. niruri was established follo

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Ibrahim, Md, Mursalin Khan, Israt Mishu, Ishrat Jahan, and Ahmed Mustafa. "Role of Phyllanthus niruri on the modulation of stress and immune responses in Nile tilapia, Oreochromis niloticus." PLOS ONE 19, no. 10 (2024): e0309793. http://dx.doi.org/10.1371/journal.pone.0309793.

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The use of nutraceuticals in aquaculture is getting attention to minimize oxidative stress and increase immunity of aquatic animals. In our experiment, we tested the potency of Phyllanthus niruri, as a stress-reducing and immune-stimulating agent in Nile tilapia, Oreochromis niloticus. We reared fish in a recirculating system for 90 days at low (5 g/L) and high (30 g/L) densities. We fed half of the low and high-density fish with commercial feed (control feed) and the other half, with 5% Phyllanthus niruri incorporated into commercial feed (supplemented feed). We assessed plasma cortisol, bloo

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MENDES, JONE CLEBSON RIBEIRO, JOÃO MARCELO ALVARENGA BRAGA, CLAUDIO NICOLETTI DE FRAGA, MARIO TOMAZELLO-FILHO, PRISCILA ORLANDINI, and SARAH MARIA ATHIÊ-SOUZA. "A new species of Phyllanthus (Phyllanthaceae) hiding in the shades in an urban Atlantic Forest in Rio de Janeiro State, Brazil." Phytotaxa 660, no. 3 (2024): 278–86. http://dx.doi.org/10.11646/phytotaxa.660.3.5.

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A new and critically endangered species of Phyllanthus, endemic to the Parque Nacional da Tijuca in Rio de Janeiro State, Brazil, is described and illustrated here. Phyllanthus celatus is placed in Phyllanthus subgenus Phyllanthus section Phyllanthus subsection Phyllanthus. Morphologically it resembles P. augustinii, P. lobatus and P. niruri, but differs mainly by presenting reddish primary, secondary and intersecondary veins on the abaxial surface (vs absent in both species), and 5-lobed pistillate disc (vs entire only in P. augustinii and P. niruri). Of these, only P. lobatus has a lobed dis

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V., Ramamurthy. "STUDIES ON ETHANOLIC LEAF EXTRACT OF PHYLLANTHUS NIRURI AND ITS EFFECT ON AFLATOXIN INTOXICATED MALE ALBINO RATS." *Corresponding author: Assistant Professor, P.G. and Research Department of Biochemistry, Marudupandiyar College, Vallam, Thanjavur, 613 403, Tamil Nadu, India, e-mail: v.ramamoorthy07@gmail.com, Mobile: +91 9943728616. International Journal of Zoology and Applied Biosciences 1, no. 1 (2016): 1–6. https://doi.org/10.5281/zenodo.1306371.

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Aflatoxin is an environmental toxicant which frequently contaminates foodstuffs in different parts of the world. The present investigation was an attempt to evaluate the possible ameliorative effects of Phyllanthus niruri on aflatoxins induced serological and biochemical changes in liver of rats. In the current study, toxicity was developed by oral administration of aflatoxin at a dose of (200 μg/kg body weight) for 40 days in male rats. P. niruri (300 mg/kg body weight) was given simultaneously for 40 days. Administration of P. s. niruri lowered the level of lipid peroxidation and enhanced

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Sabdoningrum, Emy Koestanti, Sri Hidanah, Retno Sri Wahjuni, Sri Chusniati, and Arimbi Arimbi. "An In Vitro Antibacterial Activity Test of Meniran Herbs’(Phyllanthus Niruri L.) Ethanol ExtractAgainst Mycoplasma gallisepticum causes Chronic Respiratory Disease (CRD) in Broiler Chickens." KnE Life Sciences 3, no. 6 (2017): 48. http://dx.doi.org/10.18502/kls.v3i6.1106.

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Chronic Respiratory Disease (CRD) is a chicken respiratory disease that attacks both broilers and layers. Chronic Respiratory Disease (CRD) has important economic significance in the intensification of chicken farms because this disease can cause huge economic losses. Meniran plant (Phyllanthus niruri Linn) is one of the plants that can be used as prevention and alternative treatment as a substitute of antibiotic caused by Mycoplasma galisepticum causes Chronic Respiratory Disease (CRD) in broiler chickens. The chemicals contained in meniran include tannins, saponins, alkaloids as antibacteria

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Vishal*, Dr. Dev Prakash Dahiya Anchal Sankhyan Ankit Sharma. "Phytochemistry, Pharmacological Potential, And Traditional Uses of Asparagus Racemosus: A Comprehensive Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 2022–27. https://doi.org/10.5281/zenodo.15062486.

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Phyllanthus niruri, known as the "stone breaker", is a medicinal plant with a long history of use by indigenous peoples. In this review, a critical appraisal of the medicinal properties and therapeutic potential of Phyllanthus in various pharmacological actions, particularly antiviral, hepatoprotective, antioxidant, anti-inflammatory, antidiabetic and nephro-protective effects. However, the bioactive compounds such as lignans, flavonoids and alkaloid of P. niruri has been unrevealed through recent biological studies of the therapeutic uses. The efficacy and scope of the antiviral activity, in

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Nimmi, Ishrat, Ismet Ara Jahan, M. Hemayet Hossain, Mohammad Burhan Uddin, M. Sohel Rana, and Muhammad Mahbubul Haq. "A Comparative Study on Antioxidant Properties of Two Phyllanthus Species Growing in Bangladesh." Dhaka University Journal of Pharmaceutical Sciences 11, no. 2 (2013): 191–97. http://dx.doi.org/10.3329/dujps.v11i2.14579.

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A comparative study of antioxidant properties on two varieties of Phyllanthus (Phyllanthus niruiri L. & Phyllanthus urinaria L. leaves) growing in Bangladesh was done in the present study. Five complimentary test methods namely DPPH free radical scavenging activity, reducing power assay, total antioxidant capacity, total phenolic and flavonoid contents determination were used for the evaluation of antioxidant properties of two species of Phyllanthus. In the present investigation for the evaluation of antioxidant activities the concentration is expressed by the ratio of crude sample per sol

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Eka Jayani, Nikmatul Ikhrom, Alfian Hendra Krisnawan, Nina Dewi Oktaviyanti, and Kartini Kartini. "Standardization of Phyllanthus niruri and Sonchus arvensis as Components of Scientific Jamu." Majalah Obat Tradisional 25, no. 1 (2020): 7. http://dx.doi.org/10.22146/mot.45955.

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Saintifikasi Jamu, or the scientific investigation of Jamu, is an evidence-based process to ensure the safety and efficacy of herbal medicine through health service research. Jamu has been empirically explored as a composition of various crude drugs, hence called as Scientific Jamu. Phyllanthus niruri and Sonchus arvensis are two of the 30 medicinal plants processed into Scientific Jamu. Components of the Scientific Jamu are standardized to ensure that these materials meet the predefined quality. This study was aimed to determine the specific parameters (macroscopic, microscopic, total flavono

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Rahmi, Miftahul, and Hesty Parbuntari. "Pengaruh Metode Ekstraksi Maceration Vortex Technique terhadap Total Flavonoid Content dari Daun Meniran (Phyllanthus niruri L.)." MASALIQ 5, no. 4 (2025): 2031–41. https://doi.org/10.58578/masaliq.v5i4.6826.

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Phyllanthus niruri L., a medicinal plant from the Phyllanthaceae family, is widely recognized in traditional medicine for its flavonoid content in the leaves, which functions as a natural antioxidant protecting cells from damage caused by free radicals. This study aims to investigate the effect of the Maceration Vortex Technique (MVT) on the total flavonoid content of Phyllanthus niruri leaves. The method involved a 2-hour maceration process followed by 5 minutes of vortexing using 70% ethanol as the solvent. Total flavonoid content was analyzed using UV-Vis spectrophotometry at a maximum wave

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Araújo, Otilda Fátima, Elizabeth Betty Elok Kristiani, Sri Kasmiyati, and Laurentius Hartanto Nugroho. "The Phytochemical and Biological Activities of Two <i>Phyllanthus </i>Species: Insights into Metabolit, Antioxidant and Antibacterial Activity." Biosaintifika: Journal of Biology & Biology Education 16, no. 3 (2024): 403–14. https://doi.org/10.15294/biosaintifika.v16i3.13944.

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Phylanthus species, including P. niruri and P. urinaria have pharmacological potential due to their rich phytochemical composition. People usually used this plant for medicinal treatments. This study aimed to compare the phytochemical and antioxidant and antibacterial activities of two Phyllanthus species. The whole of plants was extracted using maceration method with ethanol as solvent. Phytochemical content analyzed using spectrophotometer. The reagent used for each compounds that were Folin-ciocalteu for phenolics, AlCl3 for flavonoid, dimethyl sulfoxide for chlorophyll and carotenoid. Bioa

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