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1

Shoghi, Kalkhoran Elham. "Physico-Chemical Characterization of Drugs: Acidity and Solubility." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/98463.

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The aim of the present work was to contribute to establish robust and high throughput methodology of interest in the "Drug Discovery" step commonly done in pharmaceutical laboratories. This purpose involves the exploration of the possibilities of the potentiometric Sirius methodology to determine both acidity constants and solubilities of drugs and other bioactive compounds and also to do a study about how to improve bioavailability of a model drug, Amphotericine 8, by increasing its dissolution rate. In the first part of this project, the acidic dissociation enthalpies and constants of anilin
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2

MANCINI, ALESSANDRO. "Physico-Chemical Characterization of Emissions from Braking Operation." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2023. https://hdl.handle.net/10281/402444.

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La tesi esplora le correlazioni fra composizione chimica del particolato emesso in frenata e alcuni fattori quali: i) le combinazioni di materiali che compongono l'interfaccia tribologica; ii) le condizioni di guida; iii) le frazioni dimensionali in cui vengono prodotti i particolati<br>This thesis reports on the correlations between the compositional features of the particulates produced by brakes and several determining or modulating factors, such as: i) The starting material composing the friction couple; ii) the driving conditions; and iii) the dimensional fractions in which the particulat
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3

Mirajkar, S. P. "Hydrothermal synthesis, physico- chemical characterization of omega zeolite." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1996. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2850.

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4

Brunelli, Andrea <1984&gt. "Advanced physico-chemical characterization of engineered nanomaterials in nanotoxicology." Doctoral thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/4656.

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L'ampio utilizzo di nanomateriali ingegnerizzati (ENM) in svariati prodotti sta suscitando una crescente attenzione sull potenziale rischio di ENM nei confronti della salute umana e l'ambiente. Nonostante le indagini tossicologiche fin qui condotte, solo in poche di esse è stata condotta la caratterizzazione di ENM prima, durante e dopo i test tossicologici. In questa tesi, all’interno del progetto europeo EU-FP7 (ENPRA) e nazionale (PRIN 2009), è stata effettuata una caratterizzazione completa di alcuni più diffusi ENM (i.e. n-TiO2, n-ZnO, n-Ag e MWCNT). In primo luogo, sono stati aggiornati
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5

Medini, Federico. "Physico-chemical characterization of a surface barrier discharge plasma source." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019.

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Cold Atmospheric pressure Plasmas (CAP) generated by Dielectric Barrier Discharges (DBDs) are being studied and developed for an ever-widening range of applications in both biomedical and industrial areas. In particular surface DBDs (SDBDs), consisting of a planar powered electrode separated from a grounded mesh by a thin dielectric layer, have been gaining great interest for their ability to produce highly reactive atmospheres at close-to-environmental temperature and almost independent from the electrical properties of the target, which is treated in the afterglow of the surface plasma. Th
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6

Lodi, Alessia. "Physico-chemical and molecular characterization of soy bread containing almond." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1158163372.

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7

Kessler, Anne Karoline [Verfasser]. "Physico-chemical characterization of novel casein-surfactant micelles / Anne Karoline Kessler." München : Verlag Dr. Hut, 2015. http://d-nb.info/1067708049/34.

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8

Kessler, Anne [Verfasser]. "Physico-chemical characterization of novel casein-surfactant micelles / Anne Karoline Kessler." München : Verlag Dr. Hut, 2015. http://d-nb.info/1067708049/34.

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9

Botteon, Alessandra <1987&gt. "MA-XRF analysis on paintings and physico-chemical characterization of smalt." Master's Degree Thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/2340.

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The aim of this research was, on the one hand, the investigation of two paintings using a mobile scanning macro-XRF systems (MA-XRF) while, on the other hand, a chemical-physical characterization of smalt, a blue potash glass pigment containing cobalt that is present in the two paintings,, was carried out. For this purpose, scanning electron microscopy coupled to an energy dispersive X-Ray spectrometer (SEM-EDS) and X-ray absorption near-edge spectroscopy with synchrotron radiation as source (SR-XANES) measurements were performed. Two paintings, Ritratto di Michelangelo attributed to S. del
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10

De, Zorzi Chiara <1976&gt. "Physico-chemical Characterization of Glass Surfaces: New Surface-related Analytical Approaches." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/20493.

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Since ancient times glass was used as storage material for ointments, medicinal remedies and cosmetics for its properties of inertness and product protection. Along the centuries the technology has developed dedicated glasses for pharmaceutical use, improving their mechanical and chemical performances up to the modern borosilicate glasses. Meanwhile the technology is trying to meet the needs of new complex and sensitive drugs, the necessity of new analytical approaches has increased for a better overview of the content-material interactions to complement the classical pharmacopoeia analysis. F
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11

Tiziani, Stefano. "Physico-chemical characterization of a novel functional food tomato juice with soy /." Columbus, Ohio : Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1139765227.

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12

Liu, Qiang. "Characterization of physico-chemical properties of starch from various potatoes and other sources." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq25247.pdf.

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13

Rapovy, Shannon Marie. "Characterization of the Physico-chemical Properties of the Novel Signaling Lipid Diacylglycerol Pyrophosphate." Kent State University Honors College / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1335810423.

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14

Wessman, Per. "Physico-Chemical Investigations of, and Characterization of Model Membranes for, Lipid-Peptide Interactions." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-89432.

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15

Spampinato, Valentina. "Physico-chemical characterization of ultra thin films of functional supramolecular systems on surfaces." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/939.

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The aim of this PhD thesis is the development of new metodologies for surface anchoring of molecular and supramolecular systems for applications in molecular electronics and photonics, and for preparation of devices for molecular recognition. The systems are made up, as usually, of hybrid systems, divided in two parts, a molecular one and a solid support. The molecular part performs the desired function, while the solid support (metal or semiconductor on which the molecules are bound) allows to conjunct its properties with molecular system properties and, moreover, to help the correct orienta
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16

Keymeulen, Flore. "Development and physico-chemical characterization of supramolecular systems for anion recognition in aqueous media." Doctoral thesis, Universite Libre de Bruxelles, 2016. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/223788.

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Anion recognition is a topical area of research warranted by the potential applications of anion receptors in environmental and biological monitoring. Anions are indeed widespread in nature, are involved in many biochemical processes and are also major aqueous pollutants. Molecular receptors able to recognize anions with high affinity and selectivity in organic solvents are well documented in the literature but only few systems are efficient in aqueous media. Water is undeniably a particularly challenging solvent to work with due to the competition of water in the recognition process. Moreover
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17

Durve, Tushar Subhash. "A PHYSICO-CHEMICAL CHARACTERIZATION OF SALT CAKE DISSOLUTION AND STUDY OF SODIUM PHOSPHATE DODECHYDRATE PLUG REMEDIATION." MSSTATE, 2003. http://sun.library.msstate.edu/ETD-db/theses/available/etd-07112003-135708/.

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This thesis is divided into two projects. The first project investigates the dissolution of the Hanford salt cakes, the chemical properties of the effluent and the physical properties such as viscosity of the effluent, the porosity and the permeability of the salt cake bed as the dissolution proceeds. The chemical results are compared to predictions using a thermodynamic model. Physical properties are important because they govern the rate at which the Hanford tanks can be emptied thus facilitating the remediation process. Two simulants were investigated for the dissolution process. The chemic
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18

Allen, Christine Jane. "Polycaprolactone-b-poly(ethylene oxide) copolymer micelles, physico-chemical characterization and application in drug delivery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0029/NQ64495.pdf.

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19

Allen, Christine Jane. "Polycaprolactone-♭-poly(ethylene oxide) copolymer micelles : physico-chemical characterization and application in drug delivery." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35557.

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This thesis describes the preparation, characterization and biological study of block copolymer aggregates as drug delivery vehicles. A novel method is described for the synthesis of biodegradable and biocompatible copolymers of polycaprolactone-b-poly(ethylene oxide). The copolymers and their aggregates are then characterized with special attention given to properties which are of most interest to applications in drug delivery such as copolymer composition, thermal behavior, critical water content, critical micelle concentration, partition coefficient of hydrophobic solubilizates, morphology
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20

Schindler, Gustav Joseph. "Qualitative and semi-quantitative physico-chemical characterization of some calcium phosphate implant and bone samples." Master's thesis, University of Cape Town, 1991. http://hdl.handle.net/11427/16006.

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Bibliography pages 122-132.<br>Ten calcium phosphate implant substances (six of natural origin, four of synthetic origin) and several bone samples from a single human skeleton have been qualitatively and semi-quantitatively characterized with respect to several physico-chemical properties. Analysis involved the techniques of X-ray powder diffraction, infra-red spectroscopy, inductively-coupled plasma atomic emission spectroscopy, atomic absorption spectroscopy, and thermal decomposition. In addition, a series of adsorption/exchange experiments were conducted in which implant and bone samples w
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21

Mousavipak, Niloofar. "Physico-chemical characterization of iranian turquoises : a tentative to trace middle-eastern turquoise-bearing artifacts." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSE1021.

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Cette étude a consisté en la comparaison de turquoises CuAl6(PO4)4(OH)8.4H2O de diverses mines historiques d'Iran (Perse) à celles d'autres localités régionales afin de trouver potentiellement des caractéristiques discriminantes permettant d'identifier la provenance de bijoux ou d’artefacts à turquoise. Des échantillons de mines de turquoise ont été recueillis auprès de trois sources principales : Neyshapour, Damghan et Kerman et de couleur différente. De plus des bijoux à turquoise du Musée des Arts Décoratifs de Paris (MAD) ont également été analysé. Les spectroscopies vibrationnelles Raman
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22

FIDECKA, KATARZYNA FIDECKA. "HALLOYSITE CLAY NANOTUBES FOR BIOMEDICAL AND INDUSTRIAL APPLICATIONS: OPTIMIZATION OF THEIR PHYSICO-CHEMICAL PROPERTIES." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/704564.

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Present PhD thesis aimed to investigate relatively unknown properties of halloysite nanoparticles, as well as to further examine HNTs as potential drug nanocarriers. NPs loading and release characteristics were studied using model active molecules: magnesium monoperoxyphthalate (MMPP), aspirin and epirubicin. The research was fulfilled with formation of complex multi-functional nanoarchitectures, which apart from ability to deliver incorporated drugs, showed the potential of controlled and sustain release of therapeutics, biocompatible and bioresorbable characteristics as well as potential tar
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23

Joseph, Michael Vadakekara. "Extrusion, physico-chemical characterization and nutritional evaluation of sorghum-based high protein, micronutrient fortified blended foods." Diss., Kansas State University, 2016. http://hdl.handle.net/2097/32907.

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Doctor of Philosophy<br>Department of Grain Science and Industry<br>Sajid Alavi<br>The feasibility of using a wheat flour mill to refine corn, sorghum and cowpea was studied. Milling of white sorghum grain resulted in decrease in fiber content from 1.89% to 0.38% and 0.45% in raw, finely milled and coarsely milled sorghum respectively. Similarly, there was a reduction in fat (3.17% to 1.75% and 0.51%) content from raw to fine and coarse milled fractions. Starch content increased from 61.85% in raw to 69.80% in fine and 72.30% in coarse fractions. Protein content was almost unchanged at about 7
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24

Pagano, Bruno. "Physico-chemical characterization of DNA G-quadruplexes and their interaction with proteins and potential anticancer agents." Doctoral thesis, Universita degli studi di Salerno, 2011. http://hdl.handle.net/10556/163.

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2006 - 2007<br>Negli ultimi anni è stato dimostrato che sequenze di DNA (o RNA) ricche in guanine sono in grado di formare una nuova classe di strutture: le quadruple eliche. Importante e' la presenza di quadruple eliche in regioni promotrici e regolatrici di molti geni e nella parte terminale dei cromosomi, i telomeri. Recentemente, lo studio di queste molecole ha avuto un notevole sviluppo grazie alle diverse applicazioni che esse potrebbero avere in campo medico e farmaceutico. In particolare, le quadruple eliche hanno una potenziale applicazione nella terapia anticancro quali inibito
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25

Mishra, Dipu Kumar. "Some novel transition metal complexes of polydentate ligands: synthesis, physico-chemical characterization and DNA Interaction study." Thesis, University of North Bengal, 2021. http://ir.nbu.ac.in/handle/123456789/4759.

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26

Das, Ananya. "Novel transition metal complexes of some B-cyclodextrin based polydentate ligands: synthesis and physico-chemical characterization." Thesis, University of North Bengal, 2021. http://ir.nbu.ac.in/handle/123456789/4333.

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27

De, Bernardin Paolo. "Preparation and physico-chemical characterization of supramolecular fluoride receptors based on uranyl-salophen complexes incorporated within micelles." Doctoral thesis, Universite Libre de Bruxelles, 2012. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209671.

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The development of selective and sensitive sensors for anionic species in water is a growing field of research. In particular, the detection of fluoride in aqueous samples is of great interest because of health related problems attributed to this anion. Furthermore its small size and its high hydration energy make it a particularly <p>challenging species to recognize in water. <p>Uranyl-salophen receptors have shown to be good receptors for this anion in organic solvents due to their hard Lewis acid character which makes them good binders for the hard Lewis base fluoride. However they are not
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28

Bernardo, Maria Manuel Serrano. "Physico-chemical characterization of chars produced in the co-pyrolysis of wastes and possible routes of valorisation." Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/10213.

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Thesis submitted for the Degree in Master of Energy and Bioenergy<br>A presente dissertação tem como objectivo principal o estudo da valorização dos carvões obtidos na co-pirólise de resíduos de plásticos, pneus e biomassa florestal. Os carvões pirolíticos foram submetidos a um tratamento multietápico tendo em vista a obtenção de materiais carbonosos de valor acrescentado. Realizou-se uma caracterização físico-química dos carvões tratados tendo em vista o estudo de possíveis aplicações destes materiais, nomeadamente, a possibilidade de serem utilizados como adsorventes de poluentes. Os carvõ
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Saha, Sanjoy. "Ionic Liquid-Supported Schiff Bases and their Transition Metal Complexes: Synthesis, Physico-Chemical Characterization and Biological Activities." Thesis, University of North Bengal, 2018. http://ir.nbu.ac.in/handle/123456789/2785.

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30

Ramahlo, Masetle Nelson. "Physico-chemical and biological characterization of soils from selected farmlands around three mining sites in Phalaborwa, Limpopo Province." Thesis, University of Limpopo (Turfloop Campus), 2013. http://hdl.handle.net/10386/1127.

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Thesis (M.Sc. (Soil Science)) --University of Limpopo, 2013<br>The study was conducted to assess the impact of mining activities on selected soil physical, chemical and microbial properties on farmlands around three selected mining sites. Nine soil samples were collected from each of the following farms : Hans Merensky, Mogoboya and Leon Tom, Foskor Mine and JCI mining sites, respectively. Additional nine soil samples were collected from non-polluted Waterbok farm that serves as a control for the purpose of comparison. The samples were taken at 0–15, 15–30, 30–45 cm depths at three sampling po
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31

Phefadu, Kopano Conferance. "Physico-chemical characterization and spatial variability of soils in the research block at University of Limpopo Experimental Farm." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1686.

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Thesis (MSc. (Soil Science)) -- University of Limpopo, 2015<br>There exists a considerable level of spatial variability in soil physical and chemical properties within the research block; and the soils are generally shallow. Of all the measured parameters, electrical conductivity, Bray-1 P, exchangeable potassium, calcium and sodium as well as extractable iron and zinc showed a huge percent of variation across the field. Soil variability maps indicated the degree of variability within the research block. The spatial variability of the characterized parameters was significant across the researc
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32

Afrassiabian, Zahra. "Multiscale investigation of caking phenomenon of lactose powders : from physico-chemical aspects to industrial applications." Thesis, Compiègne, 2019. http://www.theses.fr/2019COMP2475/document.

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Cette thèse porte sur le problème fondamental du mottage des poudres suite aux mécanismes de transition de phase. Le projet vise à étudier l'impact des facteurs intrinsèques (structure moléculaire des matériaux, propriétés physiques et/ou physicochimiques, etc.) ou des facteurs environnementaux (conditions de stockage ou paramètres de procédé) sur la stabilité de la structure des poudres. Plus précisément, notre étude a mis en évidence le rôle prépondérant du phénomène de cristallisation et des transitions entre les différents polymorphes du lactose. L'accent a été mis sur le rôle des phénomèn
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33

Ostermann, Rainer [Verfasser]. "Design and physico-chemical characterization of nanowires and multicomponent metal oxide films with tailored mesostructure and crystallinity / Rainer Ostermann." Gießen : Universitätsbibliothek, 2011. http://d-nb.info/1062972732/34.

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34

Yuan, Yanyan. "Characterization of physico-chemical environment of Co-based multilayer mirrors working in the soft x-ray and EUV ranges." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066444/document.

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Dans ce travail, nous nous concentrons sur la caractérisation de l'environnement physico-chimique des éléments présents dans des multicouches à base de cobalt qui travaillent dans les domaines des rayons X mous et extrême ultra-violet (EUV). L'observation des modifications des interface des deux systèmes Co/Mo2C et Co/Mo2C/Y lors du recuit est important pour l'amélioration de leurs performance optique. Ils ont été étudiés en combinant des méthodes non destructives, spectroscopie d'émission des rayons X, résonance magnétique nucléaire, réflectométrie de rayons X et des méthodes destructrices, s
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35

Karaj, Shkelqim [Verfasser]. "Characterization of physico-chemical properties of Jatropha curcas L. and optimization of mechanical oil extraction and sedimentation / Shkelqim Karaj." Aachen : Shaker, 2014. http://d-nb.info/1049380452/34.

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36

Bastrop, Martin Verfasser], Karsten [Akademischer Betreuer] [Mäder, Alfred [Akademischer Betreuer] Blume, and Heike [Akademischer Betreuer] Bunjes. "Physico-chemical characterization of a novel class of bolaamphiphilic hydrogelators / Martin Bastrop. Betreuer: Karsten Mäder ; Alfred Blume ; Heike Bunjes." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2011. http://d-nb.info/1025135342/34.

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37

Hao, Yushan. "Characterization of Peat Bog CO2 and CH4 Production Potentials in relation to Peat Physico-chemical Properties and Vegetation Composition." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1562338709421684.

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38

Bhagwat, M. "Preparation and physico chemical characterization of the bhasmas of zinc and calcium and the Intermediates obtained during their synthesis." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2004. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2418.

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39

Shan, Jingning. "Synthesis of organic and inorganic compounds for OLED application: Physico-chemical characterization of new diamines, heterocycles and group 13 compounds." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/29163.

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This thesis is focused on the synthesis and characterization of organic and inorganic electroluminescent materials for organic light-emitting diodes (OLED). The synthetic work was aimed at several of the key components of multilayer OLEDs and followed the latest developments in this area. Three types of OLED materials, namely hole-transport (HT), electron-transport (ET) and emission (EM) materials in four groups were successfully synthesized. The characterization of these materials focuses on the physical and chemical features that are important in defining performance parameters. This chemist
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40

Grannan, Benjamin L. (Benjamin Lucas). "Physico-chemical characterization of the native and mutant protein cochlin, and its role in adult-onset hearing and balance loss." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/51602.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Physics, 2009.<br>Includes bibliographical references (p. 39-40).<br>This thesis investigates the role of the protein cochlin and its isoforms in DFNA9 autosomal dominant late onset senorineural loss and vestibular disorder by quantifying the concentration of cochlin in the inner fluid called perilymph. Through the use of affinity chromatography, high performance liquid chromatography, the Bradford assay, western blot analysis, and proteomics analysis by mass spectroscopy, I acquired data which suggests that the concentration of co
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41

Diarrassouba, Fatoumata. "Interactions between ß-lactoglobulin and nutraceutical ligands riboflavin, vitamin D3 and lysozyme Formation, physico-chemical and biological characterization of functional delivery scaffolds." Thesis, Université Laval, 2013. http://www.theses.ulaval.ca/2013/30500/30500.pdf.

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La protéine majeure du lactosérum, la β-lactoglobuline (βlg) est bien reconnue pour ses propriétés structurales intéressantes lui permettant d’établir des interactions avec des ligands de taille et de caractéristiques différentes. La riboflavine (RF) et la vitamine D3 (D3) ont été sélectionnées comme modèles de petits nutraceutiques amphiphiles et hydrophobes, respectivement, et le lysozyme (Lyso), comme ligand protéique de plus grande taille. La capacité de la βlg à lier la RF a été étudiée par des méthodes spectroscopiques. La βlg et la RF forment le complexe βlg-RF dont la photoactivation g
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42

Diarrassouba, Fatoumata. "Interactions between ß-lactoglobulin and nutraceutical ligands riboflavin, vitamin D₃ and lysozyme : formation, physico-chemical and biological characterization of functional delivery scaffolds." Doctoral thesis, Université Laval, 2013. http://hdl.handle.net/20.500.11794/22672.

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La protéine majeure du lactosérum, la β-lactoglobuline (βlg) est bien reconnue pour ses propriétés structurales intéressantes lui permettant d’établir des interactions avec des ligands de taille et de caractéristiques différentes. La riboflavine (RF) et la vitamine D3 (D3) ont été sélectionnées comme modèles de petits nutraceutiques amphiphiles et hydrophobes, respectivement, et le lysozyme (Lyso), comme ligand protéique de plus grande taille. La capacité de la βlg à lier la RF a été étudiée par des méthodes spectroscopiques. La βlg et la RF forment le complexe βlg-RF dont la photoactivation g
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43

Melki, Pamela. "Health impact of airborne particulate matter in Northern Lebanon : from a pilot epidemiological study to physico-chemical characterization and toxicological effects assessment." Thesis, Littoral, 2017. http://www.theses.fr/2017DUNK0444/document.

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L'exposition à la pollution atmosphérique, notamment aux particules fines (PM₂.₅), représente un risque majeur pour la santé dans le monde entier, et d'autant plus dans les pays en développement.Le Nord du Liban est ainsi affecté par plusieurs sources de pollution d'origine anthropique, urbaine et industrielle. Pourtant, dans cette région, aucune étude ne s'est intéressée à l'impact des PM₂.₅ sur la santé publique. Il faut également souligner que les mécanismes de toxicité des PM₂.₅ ne sont pas totalement identifiés. Le but de ce travail est d'étudier la nature et l'impact sanitaire de la poll
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44

DEMURTAS, MONICA. "Hydroxycinnamate-based Ionic liquids as bioactive compounds: physico-chemical characterization, biological activity and NMR insights into the effects on mutated cells metabolome." Doctoral thesis, Università degli Studi di Cagliari, 2021. http://hdl.handle.net/11584/314049.

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Nowadays, there is a strong collaboration between the research in drug discovery and drug delivery to improve pharmacokinetic and pharmacodynamic properties of new or use-consolidated drugs. With this purpose, several approaches have been proven to be fundamental for the developing of commercial drugs which are still in use. In this context, natural compounds such as Hydroxycinnamic acids (HCAs) are gaining increasing attention in pharmaceutical research due to their well-estabilished wide ranging benefits on health. HCAs are a group of phenolic products of plant secondary metabolism widely st
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45

Popa, Cristina Liana. "Caractérisation physico-chimique et ultrasonore de matériaux céramiques pour applications biomédicales." Thesis, Le Havre, 2016. http://www.theses.fr/2016LEHA0022/document.

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L’hydroxyapatite est l'un des matériaux les plus fréquemment utilisés pour le traitement des maladies des tissus durs. Le zinc est impliqué dans chaque étape du métabolisme du tissu osseux et une carence en zinc peut déterminer l'apparition de l'ostéoporose. Le dopage de l'hydroxyapatite par des ions de zinc peut créer un meilleur matériau, avec des propriétés physico-chimiques supérieures. L'objectif de cette thèse est de créer de nouveaux matériaux biocéramiques avec des propriétés spécifiques qui pourraient permettre le développement de nouvelles applications dans le domaine médical. Une at
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46

Tonelli, Giovanni. "Systèmes organisés à base de molécules hybrides lipide-nucléotides pour la délivrance des acides nucléiques." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22097/document.

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La thérapie génique est une forme de médecine moléculaire qui a des potentialités majeures dans le traitement d'un grand nombre de maladies héréditaires ou de cancers. Les acides nucléiques doivent pénétrer à l'intérieur des cellules et interagir avec la machinerie génétique présente. Une des plus grandes limitations dans l'application de ce type de traitement est le développement d'un vecteur sûr et efficace pour transporter ces molécules dans les cellules. Les vecteurs sont classifiés traditionnellement en deux grandes catégories : viral et non-viral. Les vecteurs de type viral sont les plus
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47

Graf, Gesche [Verfasser], A. [Akademischer Betreuer] Blume, and H. [Akademischer Betreuer] Heerklotz. "Physico-chemical characterization of Bolaamphiphile aggregates : the influence of chain and headgroup structure on self-assembly / Gesche Graf. Betreuer: A. Blume ; H. Heerklotz." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2011. http://d-nb.info/102530151X/34.

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48

Liu, Yinghui. "Caractérisations de matériaux pour la réalisation de supercondensateurs pour des applications automobiles." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30209.

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Dans le cadre d’une Convention CIFRE, la thèse est financée par la société Renault, ce travail vise à développer un supercondensateur carbone-carbone dont le coût de fabrication est compatible avec le marché automobile ; c’est en effet leur coût élevé qui constitue encore à l’heure actuelle un frein à leur développement. Dans une première partie de ce travail, il a été montré que l’essentiel du coût repose en grande partie sur la purification de l’électrolyte utilisé mais surtout du carbone activé, qui est le matériau actif d’électrode. Notre travail s’est donc focalisé sur l’étude du vieillis
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49

Duca, Dumitru. "Physico-chemical characterization of size-selected internal combustion engine nanoparticles and original method for measuring adsorption energies on carbonaceous surfaces by laser mass spectrometry." Thesis, Lille 1, 2020. http://www.theses.fr/2020LIL1R019.

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Les émissions de nanoparticules carbonées par le transport automobile sont au centre de nombreuses recherches en raison de leur impact sur le climat et la santé humaine. Les normes actuelles de l’Union Européenne régulent le nombre de particules émises ayant des tailles supérieures à 23 nm. Pour contribuer au développement d’une méthodologie de mesure fiable permettant de baisser cette limite à 10 nm, nous avons entrepris (dans le projet H2020 PEMS4Nano) une caractérisation physico-chimique avancée de particules sélectionnées en taille émises par un moteur essence. La composition chimique a ét
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50

Duca, Dumitru. "Physico-chemical characterization of size-selected internal combustion engine nanoparticles and original method for measuring adsorption energies on carbonaceous surfaces by laser mass spectrometry." Electronic Thesis or Diss., Université de Lille (2018-2021), 2020. http://www.theses.fr/2020LILUR019.

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Les émissions de nanoparticules carbonées par le transport automobile sont au centre de nombreuses recherches en raison de leur impact sur le climat et la santé humaine. Les normes actuelles de l’Union Européenne régulent le nombre de particules émises ayant des tailles supérieures à 23 nm. Pour contribuer au développement d’une méthodologie de mesure fiable permettant de baisser cette limite à 10 nm, nous avons entrepris (dans le projet H2020 PEMS4Nano) une caractérisation physico-chimique avancée de particules sélectionnées en taille émises par un moteur essence. La composition chimique a ét
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