Academic literature on the topic 'Physicochemical Equivalence'

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Journal articles on the topic "Physicochemical Equivalence"

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Kecman, Sanja, Svetlana Goločorbin-Kon, and Momir Mikov. "Physicochemical Equivalence Studies of Two Amlodipine Tablet Formulations." Scripta Medica 49, no. 1 (2018): 18–24. http://dx.doi.org/10.18575/msrs.sm.e.18.03.

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G.Q., Othman. "Comparative Analysis of Five Brands of Lisinopril Tablets in Yemeni Market." Yemeni Journal for Medical Sciences 8, no. 1 (2014): 25–30. http://dx.doi.org/10.20428/yjms.v8i1.780.

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Background: In poor countries such as Yemen, the cost of drugs is a factor affecting the patient’s decision to buy it and generic medicines are introduced as cheaper alternatives to the high cost brands. However, it has been believed that generic medicines are inferior in quality compared to the branded medicines. Thus, the aim of the present study is to investigate the physicochemical equivalence of five brands of tablets containing Lisinopril (antihypertensive) sourced from different retail pharmacy outlets in the Yemeni market. Methods: The quality and physicochemical equivalence of five di
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Sánchez-Nava, Luis Alberto, Urias Bautista-Sánchez, and Ana Luisa Robles-Piedras. "Pharmaceutical equivalence and similarity studies of glibenclamide tablets." GSC Biological and Pharmaceutical Sciences 7, no. 1 (2019): 096–101. https://doi.org/10.5281/zenodo.4295724.

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The&nbsp;<em>in vitro</em>&nbsp;dissolution is the physicochemical test most used to estimate the release of the drug from the pharmaceutical form. Due to the close relationship between the dissolution rate of the drug&nbsp;<em>in vitro</em>&nbsp;and the absorption in vivo, the dissolution study is considered as the necessary and sufficient criterion to allow the commercialization of a pharmaceutical product. In this study, the similarity of the dissolution profiles of different products containing glibenclamide used in the Mexican Health Sector was compared. The dissolution profiles of 7 gene
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Balser, S., B. Freudensprung, K. Huebner, et al. "P0879 The totality of evidence for FYB202 – an EU-approved and US-licensed biosimilar to reference ustekinumab." Journal of Crohn's and Colitis 19, Supplement_1 (2025): i1674—i1675. https://doi.org/10.1093/ecco-jcc/jjae190.1053.

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Abstract Background Ustekinumab is a fully human IgG1/kappa monoclonal antibody to interleukin (IL)-12/23. It is authorized for the treatment of moderate to severe plaque psoriasis, active psoriatic arthritis, and active inflammatory bowel disorder. FYB202 has been approved by both EMA and FDA in September 2024 as a biosimilar to reference ustekinumab based on extensive comparative analytical characterization data and the proof of equivalence in clinical performance. Methods A full set of critical quality attributes was investigated with a comprehensive set of analytical methods. Functional co
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Okoye, I. E, Iwuagwu, and A. M. "Physicochemical equivalence of some brands of Nifedipine retard tablets available in Nigeria." African Journal of Biotechnology 9, no. 8 (2010): 1274–79. http://dx.doi.org/10.5897/ajb09.1466.

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Maiti, Kuntal, Subhas Bhowmick, Pankaj Jain, Murlidhar Zope, Keyur Doshi, and Thennati Rajamannar. "Comparison of Physicochemical Properties of Generic Doxorubicin HCl Liposome Injection with the Reference Listed Drug." Anti-Cancer Agents in Medicinal Chemistry 18, no. 4 (2018): 597–609. http://dx.doi.org/10.2174/1871520617666171121124610.

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Background: Liposomal doxorubicin is widely used for treating ovarian cancer and Kaposi’s sarcoma. Encapsulation of doxorubicin in highly complex polyethylene glycol–coated (stealth) liposomes prolongs residence time and avoids the systemic toxicity associated with administration of the free drug. Small variations in physicochemical properties introduced during manufacture of liposomes can influence the payload of encapsulated drug, stability of liposomes under physiological conditions, and release of drug at the target tissue. Accordingly, the US Food and Drug Administration and the European
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ASTAWAN, Made, Tutik WRESDIYATI, Eko Hari PURNOMO, and Anthony PURWANTO. "Equivalence Test between the Physicochemical Properties of Transgenic and Non-Transgenic Soy Flour." Journal of Nutritional Science and Vitaminology 66, Supplement (2020): S286—S294. http://dx.doi.org/10.3177/jnsv.66.s286.

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K. Lakshmi, V. Abishek, S. Ankit Kumar, A. Devipriya,, S. Devadharshini, and X. Ashlin. "COMPARATIVE IN VITRO BIOAVAILABILITY TESTING FOR DIFFERENT BRANDS OF FLUCONAZOLE UNCOATED TABLETS." RASAYAN Journal of Chemistry 17, no. 01 (2024): 215–20. http://dx.doi.org/10.31788/rjc.2024.1718561.

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Our current study aimed to evaluate and compare the five different brands of Fluconazole tablets that are commercially available in Chennai. The physicochemical equivalence of five brands of Fluconazole tablets was determined through the evaluation of various standard parameters such as weight variation, friability, hardness, disintegration, dissolution rate, and amount of drug present. All the brands were found to be bioequivalent and comply with the official tests for weight variation, friability, disintegration, and dissolution tests. The tested brands showed identical drug release profiles
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Sunte, Bramhadev Tukaram, Aditya Navnath Shinde, and Vaibhav Ravindra Vaidya. "Screening of Marketed Formulations of Shatavari Tablets to Establish Pharmaceutical Equivalence." Journal of Drug Delivery and Therapeutics 13, no. 8 (2023): 56–59. http://dx.doi.org/10.22270/jddt.v13i8.6173.

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Using an in vitro dissolving research, compare the pharmacological equivalent of three brands of Shatavari tablets sold in India. According to IP rules, the dissolution was performed using apparatus I (the paddle device). According to the Indian Pharmacopoeia, evaluation of physicochemical characteristics including weight variation test, content uniformity test, hardness test, friability test, disintegration test, and dissolution test was conducted. For weight fluctuation, content homogeneity, hardness, friability, disintegration time, and dissolving study, all brands complied with official sp
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*Farhana Israt, Jahan, and Chisty Md. Mainuddin. "PHYSICOCHEMICAL EVALUATION OF SOME COMMERCIALLY AVAILABLE BRANDS OF ATENOLOL TABLETS OF BANGLADESH." DIU Journal of Health and Life Sciences 5, no. 1 & 2 (2018): 9–16. http://dx.doi.org/10.36481/diuhls.v05i1-2.fdhpam71.

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Atenolol, a cardiovascular drug, is mainly used to reduce blood pressure and available worldwide under various trade names. The purpose of the current study is to ascertain physicochemical equivalence among the five different brands of atenolol 100 mg tablets commercially obtainable in Bangladesh. The sample tablets were examined for their weight variation, hardness, thickness, friability and disintegration time as well as dissolution time were evaluated spectrophotometrically conferring to the official (BP/USP) methods. The results showed that all brands of tablets showed satisfied results wh
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Books on the topic "Physicochemical Equivalence"

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Joynt, Gavin M., and Gordon Y. S. Choi. Blood gas analysis in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0072.

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Arterial blood gases allow the assessment of patient oxygenation, ventilation, and acid-base status. Blood gas machines directly measure pH, and the partial pressures of carbon dioxide (PaCO2) and oxygen (PaO2) dissolved in arterial blood. Oxygenation is assessed by measuring PaO2 and arterial blood oxygen saturation (SaO2) in the context of the inspired oxygen and haemoglobin concentration, and the oxyhaemoglobin dissociation curve. Causes of arterial hypoxaemia may often be elucidated by determining the alveolar–arterial oxygen gradient. Ventilation is assessed by measuring the PaCO2 in the
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Book chapters on the topic "Physicochemical Equivalence"

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Moynihan, Humphrey A., and Abina M. Crean. "Pharmaceutical Solutions." In The Physicochemical Basis of Pharmaceuticals. Oxford University Press, 2009. http://dx.doi.org/10.1093/hesc/9780199232840.003.0002.

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This chapter discusses the main concepts relating to the dissolution and solubility of pharmaceutical compounds. Solubility and solutions are of key importance pharmaceutically as drug molecules need to be in solution in the biological fluids surrounding the site of action to achieve a therapeutic effect. Common expressions of solubility for pharmaceutical uses include mole fractions, molarity, molality, percentages, parts per million, and equivalents. Two types of solvent medium exist in the body: water-based and lipid-based. During the dissolution process, solute molecules leave their previo
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Ceri, Howard, Merle Olson, Douglas Morck, et al. "[25] The MBEC assay system: Multiple equivalent biofilms for antibiotic and biocide susceptibility testing." In Microbial Growth in Biofilms - Part B: Special Environments and Physicochemical Aspects. Elsevier, 2001. http://dx.doi.org/10.1016/s0076-6879(01)37026-x.

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Singh, Sudarshan, and Warangkana Chunglok. "Potential Application of Biopolymers as Biodegradable Plastic." In Biopolymers Towards Green and Sustainable Development. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079302122010009.

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Today, on average, we produce yearly about 300 million tons of plastic waste, equivalent to the entire human population weight around the globe. The singleuse plastics and plastic products are produced using high molecular weight polymers in combination with additives that could not be completely reprocessed. So far, only 9% of overall plastic waste produced has been recycled and around 12% has been incinerated while the remaining 79% has been accumulated as debris in terrestrial and aquatic environments. Biodegradability and recycling of plastics depend on various physicochemical properties i
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Novosel, Barbara, Vesna Mislej, and Viktor Grilc. "Basic Morphological, Thermal and Physicochemical Properties of Sewage Sludge for Its Sustainable Energy and Material Use in the Circular Economy." In Recent Perspectives in Pyrolysis Research. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101898.

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The treated sewage sludge is a smart material that provides sustainable use of energy and material that can be adapted to the needs of modern human life. Pyrolysis is one of the waste recovery operation that enables the generation of various useful groups of substances from treated sludge, which can then be utilized separately by final energy and material recovery processes: (i) solid residue (pyrogenic material), (ii) liquid fraction (bio-oil), and (iii) non-condensable gas. Those fractions are the basis for fertilizers and alternative fuel or new chemicals production. The chapter combines da
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Chimowitz, Eldred H. "Fundamentals of Thermodynamic Stability." In Introduction to Critical Phenomena in Fluids. Oxford University Press, 2005. http://dx.doi.org/10.1093/oso/9780195119305.003.0003.

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The second law of thermodynamics states that the entropy change in any spontaneous adiabatic process is greater than or equal to zero. It is a disarmingly simple statement but one that is a cornerstone of scientific theories. It is instrumental in describing the extent and direction of all physical and chemical transformations and contains within it the essential ideas for developing thermodynamic stability theory. Stability theory concerns itself with answering questions such as (1) What is a stable thermodynamic state? (2) Which conditions define the limit to this state beyond which the syst
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Frey, Perry A., and Adrian D. Hegeman. "Coenzymes I: Organic Coenzymes." In Enzymatic Reaction Mechanisms. Oxford University Press, 2007. http://dx.doi.org/10.1093/oso/9780195122589.003.0007.

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Most enzymatic reactions proceed with chemical changes that cannot be brought about by the side chains of amino acid residues. These enzymes function in cooperation with coenzymes and cofactors, which lend physicochemical potentialities not found in amino acids. Many coenzymes are organic molecules incorporating functional groups with chemical properties that enable them to facilitate reactions of certain types. These molecules bind to active sites tailored for them through evolution and equipped to assist in their coenzymatic functions. Many of these coenzymes were derived from vitamins, and
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Saltzman, W. Mark. "Cell Adhesion." In Tissue Engineering. Oxford University Press, 2004. http://dx.doi.org/10.1093/oso/9780195141306.003.0011.

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The external surface of the cell consists of a phospholipid bilayer which carries a carbohydrate-rich coat called the glycocalyx; ionizable groups within the glycocalyx, such as sialic acid (N-acetyl neuraminate), contribute a net negative charge to the cell surface. Many of the carbohydrates that form the glycocalyx are bound to membrane-associated proteins. Each of these components— phospholipid bilayer, carbohydrate-rich coat, membrane-associated protein—has distinct physicochemical characteristics and is abundant. Plasma membranes contain ∼50% protein, ∼45% lipid, and ∼5% carbohydrate by w
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Yaman, Hulya. "PLANT-BASED MILK ALTERNATIVES: RISING TREND AND NUTRITIONAL PERSPECTIVE." In Futuristic Trends in Agriculture Engineering & Food Sciences Volume 3 Book 7. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bcag7p1ch11.

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With the growing emphasis on health, ethical values, and sustainability, consumers have shifted towards reducing their consumption of animal-based food products and showing a tendency for plant-based alternatives. The recent coronavirus pandemic has further heightened consumer interest in novel and diverse products. Consequently, the food industry has responded by developing innovative plant-based beverages that closely imitate physicochemical and sensory properties of animal sources milk. The origins of plant-based milk alternatives, which continue to enjoy popularity today, can be traced bac
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Conference papers on the topic "Physicochemical Equivalence"

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Parsinejad, Farzan, Edwin Shirk, and Hameed Metghalchi. "Reformed Fuel and Its Properties, Burning Speeds and Flame Characteristics." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-80047.

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Premixed, lean burn combustion research has been focused for years on extending the lean flammability limit while maintaining both stable ignition and turbulent flame propagation. Burning speed is a fundamental physicochemical property of homogenous fuel/oxygen/diluent mixtures. It determines the rate of energy released during combustion and is of basic importance for developing and testing chemical kinetic models of hydrocarbons. The burning speed and flame structure of blends of reformed fuel and Methane-air mixtures have been studied using two similar constant volumes; a cylindrical vessel
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Arango Meneses, Juan Fernando, Mario Andrés Palacio Vega, Jorge Mario Mendoza Fandiño, Rafael David Gómez Vásquez, and Álvaro Ángel Arrieta Almario. "A Method to Determinate the Energy Potential Generation From Biomass Gasification." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51633.

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This paper is about the development of a computational method to determinate the energy generation potential from residual biomass gasification, in function of the variables and working conditions as the equivalence ratio (ER), and the elemental composition of the biomass, using air as gasifying agent; and by this way promote the generation of low cost energy, whether it be electrical or mechanical energy in order to take advantage of products which normally have no value added. This method was developed using the simulation software of chemical and thermodynamic processes Aspen HYSYS®, this s
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Muppala, Siva P. R., and Miltiadis V. Papalexandris. "A Modeling Approach for Hydrogen-Doped Lean Premixed Turbulent Combustion." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-13861.

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In this study, we investigate some preliminary reaction model predictions analytically in comparison with experimental premixed turbulent combustion data from four different flame configurations, which include i) high-jet enveloped, ii) expanding spherical, iii) Bunsen-like, and iv) wide-angled diffuser flames. The special intent of the present work is to evaluate the workability range of the model to hydrogen and hydrogen-doped hydrocarbon mixtures, emphasizing on the significance of preferential diffusion, PD, and Le effects in premixed turbulent flames. This is carried out in two phases: fi
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Bousbaa, Hamza, Khatir NAIMA, Medjahed Lamia, Mohammed Benramdane, Dhinesh Balasubramanian, and Anish Jafrin Thilak Johnson. "Physicochemical Characterization and Potential Applications of Biodiesel Produced from Industrial Fish Waste." In Automotive Technical Papers. SAE International, 2024. http://dx.doi.org/10.4271/2024-01-5106.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Biofuels are gaining significant global attention as renewable and alternative energy sources, produced from various materials through different extraction methods and conversion processes. Food industry generates not only substantial organic waste, presenting economic and ecological challenges but also potential opportunities for valorization. This study focuses on recovering industrial fish waste from the manufacture of canned tuna, specifically targeting non-food and abundant fish co-products such as heads, bones, ski
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Tarabet, Lyes. "Experimental Investigation on a DI Diesel Engine Fuelled with Diesel-Like Fuel Obtained by Waste Lubricant Oil Pyrolysis." In 16th International Conference on Engines & Vehicles. SAE International, 2023. http://dx.doi.org/10.4271/2023-24-0050.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;In the last decades, waste lubricating oil (WLO) has attracted a great attention due to its strong effect on the environment degradation. Due to the high content of hydrocarbons in the WLO, these huge quantities could be interesting for recovery as a fuel for internal combustion engines. In the present work, an experimental study is conducted on a DI diesel engine operating with a diesel-like fuel (DLF) obtained by converting WLO via a catalytic pyrolysis process. The DLF physicochemical properties have shown a good agre
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Gibon, Veronique, and Marc Kellens. "Fractionation of palm and palm kernel oils for designing high quality commodity and specialty fats." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/yjih6211.

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Fractionation is the most important application of fat crystallization in edible oil processing. This process commonly consists of a controlled crystallization in bulk crystallizers followed by a separation of the liquid from the crystalline fraction, nowadays mostly carried out with membrane press filters. The motive for this process is evident: since nature endows each fat with a particular composition and distribution of the fatty acids on the glycerol, their use in specific applications is limited. Palm oil is the most fractionated oil worldwide; its potential for multi-step dry fractionat
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Salager, Jean-Louis, Jesus Ontiveros, and Ronald Marquez. "How to use in practice a simplified HLDN linear equation for surfactant mixtures." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/uthm3166.

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In 1948 Winsor proposed the R ratio of the interactions at interface of the adsorbed surfactant molecules with oil (Aco) and water (Acw). At the R=Aco/Acw=1 condition, a three-phase behavior was attained. This occurrence in a continuous scan of a formulation variable, susceptible to change any interaction, was also mentioned to correspond to a low interfacial tension and low emulsion stability, among other properties. In 1975, Enhanced Oil Recovery initial studies indicated the necessity of attaining a very low interfacial tension minimum, i.e., the R=1 physicochemical balance situation presen
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Zhang, J. C., J. Li, Z. H. Li, W. Lian, P. J. Hu, and H. L. Huang. "Study on the Dynamic Change Law of Collapse Pressure in Mudstone Strata-Taking Block D as an Example." In 57th U.S. Rock Mechanics/Geomechanics Symposium. ARMA, 2023. http://dx.doi.org/10.56952/arma-2023-0125.

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ABSTRACT The mechanical-chemical coupling reaction occurs when drilling fluid intrudes into mudstone, which leads to the increase of collapse pressure. In this paper, a dynamic calculation model of collapse pressure with drilling fluid intrusion time is established according to the Mohr-Coulomb criterion. Then the pattern of drilling fluid intrusion into the core of Block D and the change of rock mechanical characteristics after intrusion are analyzed by experiments. Finally, the dynamic collapse pressure of well X in Block D was predicted by combining the reservoir section parameters. The res
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