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Journal articles on the topic 'Physiologic impact'

Author: Grafiati

Published: 31 May 2025

Last updated: 31 July 2025

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1

Obermeyer, Robert J., Nina S. Cohen, and Dawn E. Jaroszewski. "The physiologic impact of pectus excavatum repair." Seminars in Pediatric Surgery 27, no. 3 (2018): 127–32. http://dx.doi.org/10.1053/j.sempedsurg.2018.05.005.

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2

Ongkasuwan, Julina, Katherine C. Yung, and Mark S. Courey. "The physiologic impact of transnasal flexible endoscopy." Laryngoscope 122, no. 6 (2012): 1331–34. http://dx.doi.org/10.1002/lary.23358.

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3

Goh, Yau Hong, and Kheng Ann Lim. "The physiologic impact of sleep apnea on wakefulness." Otolaryngologic Clinics of North America 36, no. 3 (2003): 423–35. http://dx.doi.org/10.1016/s0030-6665(02)00174-3.

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4

Fuschino, MAJ Wanda. "Physiologic Changes of Pregnancy: Impact on Critical Care." Critical Care Nursing Clinics of North America 4, no. 4 (1992): 691–701. http://dx.doi.org/10.1016/s0899-5885(18)30619-1.

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5

Alverson, Dale C. "The Physiologic Impact of Anemia in the Neonate." Clinics in Perinatology 22, no. 3 (1995): 609–25. http://dx.doi.org/10.1016/s0095-5108(18)30271-9.

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6

Moss, Noah, and Donna M. Mancini. "Impact of LVAD speed change on physiologic functions." Journal of Heart and Lung Transplantation 38, no. 8 (2019): 877–78. http://dx.doi.org/10.1016/j.healun.2019.05.009.

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7

Bingener, Juliane, Erica A. Loomis, Marianne Huebner, and Christopher J. Gostout. "Randomized trial on the physiologic impact of NOTES." Surgical Endoscopy 29, no. 12 (2015): 3551–58. http://dx.doi.org/10.1007/s00464-015-4106-0.

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8

Pillai, Jay J., Domenico Zaca, and Asim Choudhri. "Clinical Impact of Integrated Physiologic Brain Tumor Imaging." Technology in Cancer Research & Treatment 9, no. 4 (2010): 359–80. http://dx.doi.org/10.1177/153303461000900406.

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9

Li, Xiu Rong, Yi Xing Liu, Hai Peng Yu, and Jian Li. "Evaluation of the Surface Roughness of Wood-Based Environmental Materials and its Impact on Human Psychology and Physiology." Advanced Materials Research 113-116 (June 2010): 932–37. http://dx.doi.org/10.4028/www.scientific.net/amr.113-116.932.

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According to the three-factor theory, the surface roughness of different wood-based environmental materials was evaluated using the surface roughness profiling instrument, and the underlying effective factors of the differences were analyzed. The psycho-physiological examination of the materials’ roughness on human psychology and physiology was also carried out. During the examination, physical roughness factors of the materials were treated as the independent variable, and the heart rate variability (HRV) and dynamic blood pressure (DBP) were chosen as the dependent variables. The sympathetic

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10

Walsh, M. C. "Impact of a Physiologic Definition on Bronchopulmonary Dysplasia Rates." PEDIATRICS 114, no. 5 (2004): 1305–11. http://dx.doi.org/10.1542/peds.2004-0204.

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11

Harber, Philip, Silverio Santiago, Siddharth Bansal, Yihang Liu, David Yun, and Samantha Wu. "Respirator Physiologic Impact in Persons With Mild Respiratory Disease." Journal of Occupational and Environmental Medicine 52, no. 2 (2010): 155–62. http://dx.doi.org/10.1097/jom.0b013e3181ca0ec9.

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12

Bingener, J., E. Moran, and C. Gostout. "QS95. Randomized Trials Evaluating the Physiologic Impact of Notes." Journal of Surgical Research 151, no. 2 (2009): 286. http://dx.doi.org/10.1016/j.jss.2008.11.390.

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13

Cheuvront, Samuel N., and Robert W. Kenefick. "Dehydration: Physiology, Assessment, and Performance Effects." Comprehensive Physiology 4, no. 1 (2014): 257–85. https://doi.org/10.1002/j.2040-4603.2014.tb00543.x.

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AbstractThis article provides a comprehensive review of dehydration assessment and presents a unique evaluation of the dehydration and performance literature. The importance of osmolality and volume are emphasized when discussing the physiology, assessment, and performance effects of dehydration. The underappreciated physiologic distinction between a loss of hypo‐osmotic body water (intracellular dehydration) and an iso‐osmotic loss of body water (extracellular dehydration) is presented and argued as the single most essential aspect of dehydration assessment. The importance of diagnostic and b

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14

Yeomans, Edward R., and Larry C. Gilstrap. "Physiologic changes in pregnancy and their impact on critical care." Critical Care Medicine 33, Supplement (2005): S256—S258. http://dx.doi.org/10.1097/01.ccm.0000183540.69405.90.

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15

McConnell, Timothy R., Rebecca J. Palm, William M. Shearn, and Charles A. Laubach. "Body Fat Distribution's Impact on Physiologic Outcomes During Cardiac Rehabilitation." Journal of Cardiopulmonary Rehabilitation 19, no. 3 (1999): 162–69. http://dx.doi.org/10.1097/00008483-199905000-00003.

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16

Jedlitschky, Gabriele, Andreas Greinacher, and Heyo K. Kroemer. "Transporters in human platelets: physiologic function and impact for pharmacotherapy." Blood 119, no. 15 (2012): 3394–402. http://dx.doi.org/10.1182/blood-2011-09-336933.

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Platelets store signaling molecules (eg, serotonin and ADP) within their granules. Transporters mediate accumulation of these molecules in platelet granules and, on platelet activation, their translocation across the plasma membrane. The balance between transporter-mediated uptake and elimination of signaling molecules and drugs in platelets determines their intracellular concentrations and effects. Several members of the 2 major transporter families, ATP-binding cassette (ABC) transporters and solute carriers (SLCs), have been identified in platelets. An example of an ABC transporter is MRP4

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17

Halbower, Ann C., and M. Douglas Jones. "Physiologic Reflexes and their Impact on Resuscitation of the Newborn." Clinics in Perinatology 26, no. 3 (1999): 621–27. http://dx.doi.org/10.1016/s0095-5108(18)30040-x.

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18

Olson, DaiWai M., Meg G. Zomorodi, Michael L. James, et al. "Exploring the impact of augmenting sedation assessment with physiologic monitors." Australian Critical Care 27, no. 3 (2014): 145–50. http://dx.doi.org/10.1016/j.aucc.2013.09.001.

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19

Rigatelli, Gianluca, Marco Zuin, Fabio Dell’Avvocata, Aravinda Nanjundappa, Ramesh Daggubati, and Thach Nguyen. "Non-invasive evaluation of fluid dynamic of aortoiliac atherosclerotic disease: Impact of bifurcation angle and different stent configurations." Journal of Translational Internal Medicine 6, no. 3 (2018): 138–45. http://dx.doi.org/10.2478/jtim-2018-0020.

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Abstract Objectives To non-invasively evaluate by computational fluid dynamic (CFD) analysis the physiology and rheology of aortoiliac bifurcation disease at different angles and different stent configurations. Material and methods For the analysis, we considered a physiologic model of abdominal aorta with an iliac bifurcation set at 30°, 45° and 70° without stenosis. Subsequently, a bilateral ostial common iliac stenosis of 80% was considered for each type of bifurcation. For the stent simulation, we reconstructed Zilver vascular self-expanding (Zilver; Cook, Bloomington, MN) and Palmaz Genes

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20

DeBiasi, Erin M., and David Feller-Kopman. "Physiologic Basis of Symptoms in Pleural Disease." Seminars in Respiratory and Critical Care Medicine 40, no. 03 (2019): 305–13. http://dx.doi.org/10.1055/s-0039-1693648.

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AbstractPleural effusions are commonly encountered and have a significant impact on the respiratory system. The reported effect of thoracentesis on physiologic parameters including oxygenation, lung volumes, and respiratory mechanics is variable likely owing to studies with a small, heterogeneous population of patients.Most patients who are short of breath from pleural effusion experience relief following drainage due to improvement in the length–tension relationship of the respiratory muscles. An observed increase in oxygenation following thoracentesis is likely due to improved ventilation an

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21

Ciraulo, Luciano A., Marshall L. Robaczewski, Nicolas A. Ciraulo, et al. "Biometric Analysis of Surgeons’ Physiologic Responses During Surgery." American Surgeon 86, no. 11 (2020): 1548–52. http://dx.doi.org/10.1177/0003134820933558.

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Background Much has been written from the social science perspective surrounding surgeons’ stress and burn out. The literature is sparse in reference to scientific investigations of the hemodynamic effect of that stress. This prospective clinical study quantifies the physiologic impact of performing surgery upon the acute care surgeon. Methods Over 2.5 years, monitoring devices were affixed to surgeons prior to entering the operating room, and physiologic variables were documented every 30 minutes. Qualifying cases were projected as being greater than 2 hours with a baseline preoperative measu

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22

Pal, Sumanta Kumar, and Arti Hurria. "Impact of Age, Sex, and Comorbidity on Cancer Therapy and Disease Progression." Journal of Clinical Oncology 28, no. 26 (2010): 4086–93. http://dx.doi.org/10.1200/jco.2009.27.0579.

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A theme of personalized medicine was highlighted at the 2009 Annual Meeting of the American Society of Clinical Oncology. To this end, the current review focuses on the impact of host characteristics (such as age, sex, and comorbidity) as they pertain to cancer biology, treatment efficacy, and tolerance. Increasing age is associated with complex changes in physiology, including alterations in renal and hepatic function, and decreased bone marrow reserve. These may in turn result in alterations in pharmacokinetics and toxicity related to many commonly used anticancer agents. Using tools, such a

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23

Cornwell, William K., and Andrew Lovering. "Impact of Altitude on Cardiopulmonary and Right Ventricular Hemodynamics During Exercise." Advances in Pulmonary Hypertension 19, no. 3 (2020): 77–79. http://dx.doi.org/10.21693/1933-088x-19.3.77.

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Conveniences of modern travel allow for an increasing number of people to sojourn to mountainous, high-altitude locations for work and/or pleasure. Travel to these types of locations places unique stressors on the human body and, more specifically, the cardiovascular and pulmonary systems since ambient oxygen content declines at altitude. The physiologic response to hypoxia is a highly dynamic process that begins immediately and continues to evolve from acute (hours to days) to chronic (days to weeks) time periods. Furthermore, sojourns to hypoxic locations frequently involve exercise, which p

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24

Diskin, Charles J., Thomas J. Stokes, Linda M. Dansby, Lautrec Radcliff, and Thomas B. Carter. "Beyond Anemia: The Clinical Impact of the Physiologic Effects of Erythropoietin." Seminars in Dialysis 21, no. 5 (2008): 447–54. http://dx.doi.org/10.1111/j.1525-139x.2008.00443.x.

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25

Roberge, Raymond J., Aitor Coca, W. Jon Williams, Jeffrey B. Powell, and Andrew J. Palmiero. "Reusable elastomeric air-purifying respirators: Physiologic impact on health care workers." American Journal of Infection Control 38, no. 5 (2010): 381–86. http://dx.doi.org/10.1016/j.ajic.2009.11.006.

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26

Irwin Sherman, Tami, Thomas Blackson, Suzanne Touch, Jay Greenspan, and Thomas Shaffer. "Physiologic Effects of CPAP: Application and Monitoring." Neonatal Network 22, no. 6 (2003): 7–16. http://dx.doi.org/10.1891/0730-0832.22.6.7.

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Although a wide array of respiratory care modalities has been employed to manage neonatal respiratory distress syndrome (RDS), the recent focus has emphasized strategies that correct lung pathophysiology while protecting the lung from further insult. Continuous positive airway pressure (CPAP) has remained a viable option for NICU infants since its introduction in 1971. Current methods of monitoring allow clinicians to troubleshoot and better understand the physiologic and clinical impact of administering CPAP to neonates with RDS. This article highlights the renewed interest in CPAP therapy an

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27

Higbee, Martin D. "The Geriatric Patient: General Physiologic and Pharmacologic Considerations." Journal of Pharmacy Practice 13, no. 4 (2000): 250–62. http://dx.doi.org/10.1177/089719000001300403.

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The elderly patient is not simply an older adult and needs to have drug therapy applied with caution with regard to the physiologic changes associated with aging that impact the pharmacology and pharmacokinetics of medicinals used in this population. The elderly patient has a number of physiologic changes with age that affect metabolism, distribution, and excretion. In addition, there exists information that demonstrates changes in the pharmacodynamics of drug therapy commonly used in the elderly. This article reviews these changes.

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28

Quist Miller, Margaret, and Lizbeth Ann Morris. "Developmental Considerations in Working with Newborn Infants of Mothers with Diabetes." Neonatal Network 30, no. 1 (2011): 37–45. http://dx.doi.org/10.1891/0730-0832.30.1.37.

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AbstractInfants of diabetic mothers (IDMs) are at risk for an altered developmental course beginning with physiologic alterations in utero. This article describes physiologic and behavioral factors that impact the fetus and newborn infant and may have long-term developmental consequences. A clinical reasoning process to support development optimizes the outcomes of IDMs while in the NICU. Specific interventions are suggested.

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29

Malmberg, B., R. Persson, B. A. Jönsson, et al. "Physiologic Restitution after Night-call Duty in Anesthesiologists: Impact on Metabolic Factors." Obstetric Anesthesia Digest 28, no. 2 (2008): 96–97. http://dx.doi.org/10.1097/01.aoa.0000319811.12695.85.

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30

Graham, T. P. "Somatic Growth in Children With Single Ventricle Physiology: Impact of Physiologic State." Yearbook of Cardiology 2008 (January 2008): 143–44. http://dx.doi.org/10.1016/s0145-4145(08)03052-9.

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31

VandeVusse, Leona, Lisa Hanson, Margaret A. Berner, and Jill M. White Winters. "Impact of Self-Hypnosis in Women on Select Physiologic and Psychological Parameters." Journal of Obstetric, Gynecologic & Neonatal Nursing 39, no. 2 (2010): 159–68. http://dx.doi.org/10.1111/j.1552-6909.2010.01103.x.

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32

Marques-Magallanes, Jose A., Shankar N. Koyal, Christopher B. Cooper, Eric C. Kleerup, and Donald P. Tashkin. "Impact of Habitual Cocaine Smoking on the Physiologic Response to Maximum Exercise." Chest 112, no. 4 (1997): 1008–16. http://dx.doi.org/10.1378/chest.112.4.1008.

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33

Thomas, Alyce M., and Selina C. Mkandawire. "The Impact of Nutrition on Physiologic Changes in Persons Who Have HIV." Nursing Clinics of North America 41, no. 3 (2006): 455–68. http://dx.doi.org/10.1016/j.cnur.2006.05.002.

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34

Suvakov, Sonja, Andrea G. Kattah, Tamara Gojkovic, et al. "Impact of Aging and Cellular Senescence in the Pathophysiology of Preeclampsia." Comprehensive Physiology 13, no. 4 (2023): 5077–114. https://doi.org/10.1002/j.2040-4603.2023.tb00282.x.

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AbstractThe incidence of hypertensive disorders of pregnancy is increasing, which may be due to several factors, including an increased age at pregnancy and more comorbid health conditions during reproductive years. Preeclampsia, the most severe hypertensive disorder of pregnancy, has been associated with an increased risk of future disease, including cardiovascular and kidney diseases. Cellular senescence, the process of cell cycle arrest in response to many physiologic and maladaptive stimuli, may play an important role in the pathogenesis of preeclampsia and provide a mechanistic link to fu

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35

Spivak, Jerry L. "The Physiologic Basis for the Pharmacologic Use of Recombinant Erythropoietin." Cancer Control 5, no. 2_suppl (1998): 22–25. http://dx.doi.org/10.1177/107327489800502s05.

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36

Bailey, Vickie, Kristi Cagle, Deborah Kurtz, et al. "Modern Neonatal Transport: Sound and Vibration Levels and Their Impact on Physiological Stability." American Journal of Perinatology 36, no. 04 (2018): 352–59. http://dx.doi.org/10.1055/s-0038-1668171.

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Objective To measure sound and vibration in rotary wing air transport (RWAT) and ground ambulance transport (GAT), comparing them to current recommendations, and correlating them with physiological stability measures in transported neonates. Study Design This is a prospective cohort observational study including infants ≤ 7 days of age transported over an 8-month period. Infants with neurologic conditions were excluded. Sound and vibration was continuously measured during transport. Transport Risk Index of Physiologic Stability (TRIPS) scores were calculated from vital signs as a proxy for phy

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37

Fecteau, Jessie-F., Davorka Messmer, Suping Zhang, Bing Cui, Liguang Chen, and Thomas J. Kipps. "Impact of oxygen concentration on growth of mesenchymal stromal cells from the marrow of patients with chronic lymphocytic leukemia." Blood 121, no. 6 (2013): 971–74. http://dx.doi.org/10.1182/blood-2012-08-447813.

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38

Gordon, Veronica. "Physiological impacts of wildfire exposure on four American black bears." Wildlife Rehabilitation Bulletin 40, no. 1 (2022): 8–16. http://dx.doi.org/10.53607/wrb.v40.249.

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A substantive wildfire season in Eastern Washington in July and August 2021 led to the admittance of four American black bears (Ursus americanus) to PAWS Wildlife Center for wildfire-related injuries. The animals each suffered burns of first to fourth degree classifications in addition to trauma related to smoke inhalation. In one case, the patient experienced either permanent or transient physiologic changes to the respiratory, cardiovascular, and nervous systems. The basis for anticipating and managing trauma in wildfire-affected wildlife in these cases was extrapolated from published litera

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39

Tibbitts, Jay. "Issues Related to the Use of Canines in Toxicologic Pathology—Issues With Pharmacokinetics and Metabolism." Toxicologic Pathology 31, no. 1_suppl (2003): 17–24. http://dx.doi.org/10.1080/01926230390174896.

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The dog is a commonly used animal model by virtue of its size, well-characterized physiology, and ease of handling. For these reasons and others, dogs are also useful in pharmacokinetic and metabolism studies during the development of both human and veterinary pharmaceutical products. In comparison with humans, or with other animals, dogs have some unique physiologic attributes that can affect the disposition of drugs. Species differences in gastrointestinal physiology, metabolism, renal function, and protein binding can affect the correlation of the pharmacokinetics and toxicology of dogs wit

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40

Sprung, Charles L., Peter N. Peduzzi, Clayton H. Shatney, Michael F. Wilson, and Lerner B. Hinshaw. "THE IMPACT OF ENCEPHALOPATHY ON MORTALITY AND PHYSIOLOGIC DERANGEMENTS IN THE SEPSIS SYNDROME." Critical Care Medicine 16, no. 4 (1988): 398. http://dx.doi.org/10.1097/00003246-198804000-00079.

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41

Krebs, Nancy F. "Bioavailability of Dietary Supplements and Impact of Physiologic State: Infants, Children and Adolescents." Journal of Nutrition 131, no. 4 (2001): 1351S—1354S. http://dx.doi.org/10.1093/jn/131.4.1351s.

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42

Baber, Usman, M. Urooj Zafar, jaime uribarri, et al. "PHYSIOLOGIC IMPACT OF CHRONIC KIDNEY DISEASE ON WHOLE BLOOD CLOT KINETICS AND STRENGTH." Journal of the American College of Cardiology 59, no. 13 (2012): E2096. http://dx.doi.org/10.1016/s0735-1097(12)62097-x.

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43

Wood, B. L., and B. D. Miller. "270 Physiologic specificity of emotions and their impact on airway reactivity in asthma." International Journal of Psychophysiology 30, no. 1-2 (1998): 106. http://dx.doi.org/10.1016/s0167-8760(98)90270-7.

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44

Cruess, Dean G., and Dwight L. Evans. "Psychiatric Symptoms During HIV Disease: Physiologic Mechanisms and Potential Treatments." CNS Spectrums 8, no. 1 (2003): 20. http://dx.doi.org/10.1017/s1092852900023415.

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We are pleased to introduce this special issue of CNS Spectrums on neuropsychiatry and human immunodeficiency virus infection. The study of psychiatric manifestations of HIV has been at the forefront of research since the early 1980s. Although information has accumulated in the past 20 years, there is still a great deal to be learned. This issue includes four comprehensive reviews of the literature in the area of HIV research. The first two papers outline the prior research examining the prevalence and effects of psychiatric symptoms in HIV-positive (HIV+) individuals. The other papers summari

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45

Roy, Dr Jayeeta. "The Impact of Coccydynia with Radiological Modality: A Systemic Review." Journal of Medical Science And clinical Research 11, no. 09 (2023): 111–21. http://dx.doi.org/10.18535/jmscr/v11i9.15.

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Coccydynia, or Coccygodynia, is pain in the region of the Coccyx. Despite the identification of chronic coccygeal pain hundreds of yearsago, its treatment can be difficult and sometimes controversial because of the multifactorial nature of coccygeal pain.[1] Many Physiologic and psychological factors contribute to its etiology. Most cases of coccydynia resolve within weeks to months with or without conservative treatment, but for a few patients the pain can become chronic and debilitating.[2] Coccydynia is pain located in the coccygeal bone or the surrounding tissues. Coccydynia is a relativel

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46

Porges, Stephen W. "Vagal Tone: A Physiologic Marker of Stress Vulnerability." Pediatrics 90, no. 3 (1992): 498–504. http://dx.doi.org/10.1542/peds.90.3.498.

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Vagal tone is proposed as a novel index of stress vulnerability and reactivity with applications in all branches of medicine, and with particular value in pediatrics. The paper proposes a model emphasizing the role of the parasympathetic nervous system and particularly the vagus nerve in mediating homeostasis and defining stress. Measurement of cardiac vagal tone is proposed as a method to assess on an individual basis both the stress response and the vulnerability to stress. The method monitors the neural control of the heart via the vagus (ie, vagal tone) as an index of homeostasis. The meth

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47

Putra, Kriswandy, Putri Welda Utami Ritonga, and Haslinda Z. Tamin. "Custom ocular prosthesis with modification in impression and iris button for rehabilitation of post-enucleation eye defect: a case report." Indonesian Journal of Prosthodontics 3, no. 2 (2023): 77–81. http://dx.doi.org/10.46934/ijp.v3i2.144.

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Loss of eye have physiologic and social impact on patients, especially in pediatric patients. To overcome this problem ocular prosthesis can be made similar with the color, shape, size and movement of the patient’s eye, so the ocular prosthesis can look like natural eye. The various methods, techniques and concepts documented in this case re-port with modifications to the physiologic impression and making of iris buttons aim to get the better movement of the prosthesis and 3D profile of the iris. A 6-years-old female patient came to the USU Dental Hospital to fabricate a new eye prosthesis. Th

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48

Kowdley, Gopal C., Nishant Merchant, James P. Richardson, Justin Somerville, Myriam Gorospe, and Steven C. Cunningham. "Cancer Surgery in the Elderly." Scientific World Journal 2012 (2012): 1–9. http://dx.doi.org/10.1100/2012/303852.

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The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and mo

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49

Vijayan, Aarathi, and S. Fathimabeevi. "Dental Considerations during Pregnancy." Kerala Dental Journal 48, no. 2 (2025): 77–84. https://doi.org/10.4103/ksdj.ksdj_70_24.

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Abstract Pregnancy is a unique moment in a woman’s life, accompanied by several physiologic changes that have an impact on oral health. Pregnancy results in physiologic changes in almost all organ systems in the body mediated mainly by hormones, which influences the treatment schedule. Understanding these normal changes is essential for providing quality care for pregnant women. The general principles that apply in this situation are discussed, followed by the relevant physiologic changes and their treatment implications, the risks of various medications to the mother and foetus, the managemen

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50

Czempik, Piotr F., Dawid Gierczak, Dawid Wilczek, and Łukasz J. Krzych. "The Impact of Red Blood Cell Transfusion on Blood Lactate in Non-Bleeding Critically Ill Patients—A Retrospective Cohort Study." Journal of Clinical Medicine 11, no. 4 (2022): 1037. http://dx.doi.org/10.3390/jcm11041037.

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Anemia should preferably be managed without red blood cell transfusion (RBCT); instead, therapy should be focused on causes of anemia along with efforts to minimize blood loss. Lactate could potentially be used as a physiologic RBCT trigger, although there are some limitations to its interpretation. The aim of our study was to analyze the impact of RBCT on blood lactate with consideration of factors known to increase its concentration and to assess the usefulness of blood lactate as a potential physiologic RBCT trigger. We performed a retrospective analysis of all RBCT episodes in non-bleeding

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