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Journal articles on the topic 'Physiological aspects of Bacterial diseases'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Flores-Díaz, Marietta, Laura Monturiol-Gross, Claire Naylor, Alberto Alape-Girón, and Antje Flieger. "Bacterial Sphingomyelinases and Phospholipases as Virulence Factors." Microbiology and Molecular Biology Reviews 80, no. 3 (2016): 597–628. http://dx.doi.org/10.1128/mmbr.00082-15.

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SUMMARYBacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze sphingomyelin and glycerophospholipids, respectively, generating products identical to the ones produced by eukaryotic enzymes which play crucial roles in distinct physiological processes, including membrane dynamics, cellular signaling, migration, growth, and death. Several bacterial sphingomyelinases and phospholipases are essential for virulence of extracellular, fa

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Sun, Jun, and Yinglin Xia. "Microbiome in Colonic Carcinogenesis." Comprehensive Physiology 13, no. 3 (2023): 4685–708. https://doi.org/10.1002/j.2040-4603.2023.tb00265.x.

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AbstractMicrobiomes include bacteria, viruses, fungi, and other microbes. The microbiome modulates numerous aspects of host physiology and is critical in the pathophysiology of diseases, including colon cancer. Although gut bacterial pathogenesis has become an emerging area in colon cancer, the multi‐kingdom aspect of microbiome has yet to be explored. Similar to the bacterial component of the microbiome, the virome contains certain makeup that varies between individuals. In the current review, we introduce the concepts of microbiome and microbiota, research history, methods for modern microbi

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Condrò, Giorgia, Marta Guerini, Michela Castello, and Paola Perugini. "Acne Vulgaris, Atopic Dermatitis and Rosacea: The Role of the Skin Microbiota—A Review." Biomedicines 10, no. 10 (2022): 2523. http://dx.doi.org/10.3390/biomedicines10102523.

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The skin harbors a huge number of different microorganisms such as bacteria, fungi and viruses, and it acts as a protective shield to prevent the invasion of pathogens and to maintain the health of the commensal microbiota. Several studies, in fact, have shown the importance of the skin microbiota for healthy skin. However, this balance can be altered by intrinsic and extrinsic factors, leading to the development of skin disease, such as acne vulgaris (AV), atopic dermatitis (AD) and rosacea(RS). Although these diseases are widespread and affect both adolescents and adults, the scientific corr

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Thapa, Himadri B., Stephan P. Ebenberger, and Stefan Schild. "The Two Faces of Bacterial Membrane Vesicles: Pathophysiological Roles and Therapeutic Opportunities." Antibiotics 12, no. 6 (2023): 1045. http://dx.doi.org/10.3390/antibiotics12061045.

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Bacterial membrane vesicles (MVs) are nanosized lipid particles secreted by lysis or blebbing mechanisms from Gram-negative and -positive bacteria. It is becoming increasingly evident that MVs can promote antimicrobial resistance but also provide versatile opportunities for therapeutic exploitation. As non-living facsimiles of parent bacteria, MVs can carry multiple bioactive molecules such as proteins, lipids, nucleic acids, and metabolites, which enable them to participate in intra- and interspecific communication. Although energetically costly, the release of MVs seems beneficial for bacter

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Garcia-Grau, Iolanda, Carlos Simon, and Inmaculada Moreno. "Uterine microbiome—low biomass and high expectations†." Biology of Reproduction 101, no. 6 (2018): 1102–14. http://dx.doi.org/10.1093/biolre/ioy257.

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AbstractThe existence of different bacterial communities throughout the female reproductive tract has challenged the traditional view of human fetal development as a sterile event. There is still no consensus on what physiological microbiota exists in the upper reproductive tract of the vast majority of women who are not in periods of infection or pregnancy, and the role of bacteria that colonize the upper reproductive tract in uterine diseases or pregnancy outcomes is not well established. Despite published studies and advances in uterine microbiome sequencing, some study aspects—such as stud

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Zhao, Jing, Xinyun Li, Xiyan Hou, Chunshan Quan, and Ming Chen. "Widespread Existence of Quorum Sensing Inhibitors in Marine Bacteria: Potential Drugs to Combat Pathogens with Novel Strategies." Marine Drugs 17, no. 5 (2019): 275. http://dx.doi.org/10.3390/md17050275.

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Quorum sensing (QS) is a phenomenon of intercellular communication discovered mainly in bacteria. A QS system consisting of QS signal molecules and regulatory protein components could control physiological behaviors and virulence gene expression of bacterial pathogens. Therefore, QS inhibition could be a novel strategy to combat pathogens and related diseases. QS inhibitors (QSIs), mainly categorized into small chemical molecules and quorum quenching enzymes, could be extracted from diverse sources in marine environment and terrestrial environment. With the focus on the exploitation of marine

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Skosyrskikh, L. N., K. A. Sidorova, N. A. Tatarnikova, and M. V. Shchipakin. "Physiological justification of diagnostic and therapeutic measures for allergic flea dermatitis." International Journal of Veterinary Medicine, no. 2 (June 28, 2024): 382–92. http://dx.doi.org/10.52419/issn2072-2419.2024.2.382.

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In modern conditions, the percentage of allergic diseases increases every year. A sufficient number of studies have been devoted to the study of various aspects of the pathology under consideration in small pets, but its solution will contribute to a comfortable life for the patient. According to the conducted research, it was found that among dermatological diseases, there were such as allergic: in cats 22.2%, in dogs 15.5%; parasitic in cats 13.3%, in dogs 10.5%; fungal in cats 6.3%, in dogs 7.2%, bacterial in cats 5.8%, in dogs 6.4%; thermal in cats 5.2%, in dogs 2.3%, chemical in cats 5.3%

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Javadov, Sabzali, Andrey V. Kozlov, and Amadou K. S. Camara. "Mitochondria in Health and Diseases." Cells 9, no. 5 (2020): 1177. http://dx.doi.org/10.3390/cells9051177.

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Mitochondria are subcellular organelles evolved by endosymbiosis of bacteria with eukaryotic cells characteristics. They are the main source of ATP in the cell and play a pivotal role in cell life and cell death. Mitochondria are engaged in the pathogenesis of human diseases and aging directly or indirectly through a broad range of signaling pathways. However, despite an increased interest in mitochondria over the past decades, the mechanisms of mitochondria-mediated cell/organ dysfunction in response to pathological stimuli remain unknown. The Special Issue, “Mitochondria in Health and Diseas

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Santos, Bárbara Sttephanny Silveira, Andres Camilo Campo Arevalo, Oliver Renê Viana de Jesus, et al. "IRON DEFICIENCY ANEMIA AS A RISK FACTOR FOR DENTAL PULP DISEASES: AN INTEGRATIVE REVIEW." Brazilian Journal of Implantology and Health Sciences 6, no. 8 (2024): 1647–58. http://dx.doi.org/10.36557/2674-8169.2024v6n8p1647-1658.

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Iron deficiency anemia is characterized by reduced blood capacity to transport oxygen due to insufficient iron, an essential component of hemoglobin. This condition can have various implications for oral health, including dental pulp health. The human body must balance physiological, nutritional, and environmental factors to maintain optimal functioning. Iron salts react with gingival crevicular fluid and subgingival bacterial metabolites, staining teeth. Iron supplements typically have a highly acidic pH compromising dental enamel microhardness and increasing the risk of cavities. However, th

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Davidson, Amy L., Elie Dassa, Cedric Orelle, and Jue Chen. "Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems." Microbiology and Molecular Biology Reviews 72, no. 2 (2008): 317–64. http://dx.doi.org/10.1128/mmbr.00031-07.

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SUMMARY ATP-binding cassette (ABC) systems are universally distributed among living organisms and function in many different aspects of bacterial physiology. ABC transporters are best known for their role in the import of essential nutrients and the export of toxic molecules, but they can also mediate the transport of many other physiological substrates. In a classical transport reaction, two highly conserved ATP-binding domains or subunits couple the binding/hydrolysis of ATP to the translocation of particular substrates across the membrane, through interactions with membrane-spanning domains

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Wang, Jing-Hung, Rachna Singh, Michael Benoit, et al. "Sigma S-Dependent Antioxidant Defense Protects Stationary-Phase Escherichia coli against the Bactericidal Antibiotic Gentamicin." Antimicrobial Agents and Chemotherapy 58, no. 10 (2014): 5964–75. http://dx.doi.org/10.1128/aac.03683-14.

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ABSTRACTStationary-phase bacteria are important in disease. The σs-regulated general stress response helps them become resistant to disinfectants, but the role of σsin bacterial antibiotic resistance has not been elucidated. Loss of σsrendered stationary-phaseEscherichia colimore sensitive to the bactericidal antibiotic gentamicin (Gm), and proteomic analysis suggested involvement of a weakened antioxidant defense. Use of the psfiAgenetic reporter, 3′-(p-hydroxyphenyl) fluorescein (HPF) dye, and Amplex Red showed that Gm generated more reactive oxygen species (ROS) in the mutant. HPF measureme

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Hatheway, C. L. "Toxigenic clostridia." Clinical Microbiology Reviews 3, no. 1 (1990): 66–98. http://dx.doi.org/10.1128/cmr.3.1.66.

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Toxigenic clostridia belonging to 13 recognized species are discussed in this review. Each species or group of organisms is, in general, introduced by presenting the historical aspects of its discovery by early investigators of human and animal diseases. The diseases caused by each species or group are described and usually discussed in relation to the toxins involved in the pathology. Morphological and physiological characteristics of the organisms are described. Finally, the toxins produced by each organism are listed, with a presentation of their biological activities and physical and bioch

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Shulgina, S. M., M. P. Rykova, O. V. Kutko, et al. "Immunological Aspects of Reactivation of Latent Infections in Space Flight and Antarctica." Физиология человека 49, no. 6 (2023): 98–116. http://dx.doi.org/10.31857/s0131164623700418.

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The complex of space flight (SF) factors can have a negative impact on the human organism, including the innate and adaptive immunity. One of the negative effects of impaired functional activity of the immune system is a decrease of latent infections immunological control. During short- and long-term SF, reactivation of latent viruses was shown, while the virus was detected in body fluids for some time after returning to Earth. Despite the fact that in most cases reactivation was asymptomatic, there are fears that during long expeditions into deep space, reactivation of latent pathogens can le

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Mintz, Keith P., David R. Danforth, and Teresa Ruiz. "The Trimeric Autotransporter Adhesin EmaA and Infective Endocarditis." Pathogens 13, no. 2 (2024): 99. http://dx.doi.org/10.3390/pathogens13020099.

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Infective endocarditis (IE), a disease of the endocardial surface of the heart, is usually of bacterial origin and disproportionally affects individuals with underlying structural heart disease. Although IE is typically associated with Gram-positive bacteria, a minority of cases are caused by a group of Gram-negative species referred to as the HACEK group. These species, classically associated with the oral cavity, consist of bacteria from the genera Haemophilus (excluding Haemophilus influenzae), Aggregatibacter, Cardiobacterium, Eikenella, and Kingella. Aggregatibacter actinomycetemcomitans,

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Prado, Simone Souza, and Tiago Domingues Zucchi. "Host-Symbiont Interactions for Potentially Managing Heteropteran Pests." Psyche: A Journal of Entomology 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/269473.

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Insects in the suborder Heteroptera, the so-called true bugs, include over 40,000 species worldwide. This insect group includes many important agricultural pests and disease vectors, which often have bacterial symbionts associated with them. Some symbionts have coevolved with their hosts to the extent that host fitness is compromised with the removal or alteration of their symbiont. The first bug/microbial interactions were discovered over 50 years ago. Only recently, mainly due to advances in molecular techniques, has the nature of these associations become clearer. Some researchers have purs

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Bhat, Mujtaba Aamir, Awdhesh Kumar Mishra, Javeed Ahmad Tantray, et al. "Gut Microbiota and Cardiovascular System: An Intricate Balance of Health and the Diseased State." Life 12, no. 12 (2022): 1986. http://dx.doi.org/10.3390/life12121986.

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Gut microbiota encompasses the resident microflora of the gut. Having an intricate relationship with the host, it plays an important role in regulating physiology and in the maintenance of balance between health and disease. Though dietary habits and the environment play a critical role in shaping the gut, an imbalance (referred to as dysbiosis) serves as a driving factor in the occurrence of different diseases, including cardiovascular disease (CVD). With risk factors of hypertension, diabetes, dyslipidemia, etc., CVD accounts for a large number of deaths among men (32%) and women (35%) world

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Jalil Abed Gatie and Ibrahim Abbas Mohammed. "Study of clinical signs and post mortem changes in vaccinated and unvaccinated buffaloes experimentally infected with the virulent Pasturella multocida bacterium that causes hemorrhagic septicemia in buffaloes-South of Iraq ." University of Thi-Qar Journal of agricultural research 10, no. 1 (2021): 104–22. http://dx.doi.org/10.54174/utjagr.v10i1.123.

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Hemorrhagic septicemia is an important disease of cattle and buffaloes. Which causes disease revolutions with great economic losses in Asia and Africa, and in Iraq it is considered one of the more dangerous diseases in buffaloes than in cows. This study was prepared to reassess the vaccination program against hemorrhagic septicemia, which is used in Iraq, especially in buffaloes, due to the nature of their lives in the marshes and as a result of the epidemic that occurred in 2008 by conducting a challenge test on buffaloes directly with a study of some physiological and immunological aspects b

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Allam-Ndoul, Bénédicte, Sophie Castonguay-Paradis, and Alain Veilleux. "Gut Microbiota and Intestinal Trans-Epithelial Permeability." International Journal of Molecular Sciences 21, no. 17 (2020): 6402. http://dx.doi.org/10.3390/ijms21176402.

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Constant remodeling of tight junctions to regulate trans-epithelial permeability is essential in maintaining intestinal barrier functions and thus preventing diffusion of small molecules and bacteria to host systemic circulation. Gut microbiota dysbiosis and dysfunctional gut barrier have been correlated to a large number of diseases such as obesity, type 2 diabetes and inflammatory bowel disease. This led to the hypothesis that gut bacteria-epithelial cell interactions are key regulators of epithelial permeability through the modulation of tight junctions. Nevertheless, the molecular basis of

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Zamorano, Laura, Bartolomé Moyà, Carlos Juan, Xavier Mulet, Jesús Blázquez та Antonio Oliver. "The Pseudomonas aeruginosa CreBC Two-Component System Plays a Major Role in the Response to β-Lactams, Fitness, Biofilm Growth, and Global Regulation". Antimicrobial Agents and Chemotherapy 58, № 9 (2014): 5084–95. http://dx.doi.org/10.1128/aac.02556-14.

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ABSTRACTPseudomonas aeruginosais a ubiquitous versatile environmental microorganism with a remarkable ability to grow under diverse environmental conditions. Moreover,P. aeruginosais responsible for life-threatening infections in immunocompromised and cystic fibrosis patients, as the extraordinary capacity of this pathogen to develop antimicrobial resistance dramatically limits our therapeutic arsenal. Its large genome carries an outstanding number of genes belonging to regulatory systems, including multiple two-component sensor-regulator systems that modulate the response to the different env

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Liang, Q., K. Choi, H. Sham, B. Bressler, and B. vallance. "A2 USING BIOPSY-DERIVED ORGANOIDS AND GUT-ON-A-CHIP PLATFORM TO DEVELOP A PHYSIOLOGICALLY RELEVANT BACTERIAL INFECTION MODEL." Journal of the Canadian Association of Gastroenterology 8, Supplement_1 (2025): i1. https://doi.org/10.1093/jcag/gwae059.002.

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Abstract Background The intestine is a highly complex ecosystem, consisting of diverse cell types, dynamic interactions, and mechanical forces. These elements are key to maintaining intestinal homeostasis and modulating the risk of enteric bacterial infections. Traditional in vitro models fail to recapitulate the physiological complexity of the gut, limiting our understanding of bacterial pathogenesis and host responses. Patient-derived intestinal organoids offer a promising solution by replicating the cellular diversity and structure of the epithelium. However, conventional organoid cultures

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Asutkar, Sheetal, Yogesh Yadav, and Vasudha Asutkar. "Applied aspects of Dincharya – The Daily Regimen as per Ayurveda, directing towards health maintenance and disease prevention in present era." International Journal of Ayurvedic Medicine 14, no. 2 (2023): 317–24. http://dx.doi.org/10.47552/ijam.v14i2.3578.

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Introduction- Dinacharya means an ideal daily regimen as per Ayurveda that offers a lifestyle with beneficial physiological and psychological effects for a human body and mind. Why is it called ideal is because it harmonizes balance between body humors(Dosha),tissues(Dhatu) and wastes (Mala) power of digestion(Agni), grooms a pleasant mind, soul and sense organs and offers disease free long life. This is how health is defined by Sushruta Acharya. This idealism needs also to be understood through conceptual justification from Ayurveda. Dinacharya includes activities such waking in Bramha-muhurt

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Caruso, Gianluca, Nadezhda Golubkina, Alessio Tallarita, Magdi T. Abdelhamid, and Agnieszka Sekara. "Biodiversity, Ecology, and Secondary Metabolites Production of Endophytic Fungi Associated with Amaryllidaceae Crops." Agriculture 10, no. 11 (2020): 533. http://dx.doi.org/10.3390/agriculture10110533.

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Amaryllidaceae family comprises many crops of high market potential for the food and pharmaceutical industries. Nowadays, the utilization of plants as a source of bioactive compounds requires the plant/endophytic microbiome interactions, which affect all aspects of crop’s quantity and quality. This review highlights the taxonomy, ecology, and bioactive chemicals synthesized by endophytic fungi isolated from plants of the Amaryllidaceae family with a focus on the detection of pharmaceutically valuable plant and fungi constituents. The fungal microbiome of Amaryllidaceae is species- and tissue-d

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Posadas, I., L. Romero-Castillo, N. El Brahmi, et al. "Neutral high-generation phosphorus dendrimers inhibit macrophage-mediated inflammatory response in vitro and in vivo." Proceedings of the National Academy of Sciences 114, no. 37 (2017): E7660—E7669. http://dx.doi.org/10.1073/pnas.1704858114.

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Inflammation is part of the physiological response of the organism to infectious diseases caused by organisms such as bacteria, viruses, fungi, or parasites. Innate immunity, mediated by mononuclear phagocytes, including monocytes and macrophages, is a first line of defense against infectious diseases and plays a key role triggering the delayed adaptive response that ensures an efficient defense against pathogens. Monocytes and macrophages stimulation by pathogen antigens results in activation of different signaling pathways leading to the release of proinflammatory cytokines. However, inflamm

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Quintieri, Fanelli, and Caputo. "Antibiotic Resistant Pseudomonas Spp. Spoilers in Fresh Dairy Products: An Underestimated Risk and the Control Strategies." Foods 8, no. 9 (2019): 372. http://dx.doi.org/10.3390/foods8090372.

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Microbial multidrug resistance (MDR) is a growing threat to public health mostly because it makes the fight against microorganisms that cause lethal infections ever less effective. Thus, the surveillance on MDR microorganisms has recently been strengthened, taking into account the control of antibiotic abuse as well as the mechanisms underlying the transfer of antibiotic genes (ARGs) among microbiota naturally occurring in the environment. Indeed, ARGs are not only confined to pathogenic bacteria, whose diffusion in the clinical field has aroused serious concerns, but are widespread in saproph

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Mata-Martínez, Esperanza, María Guadalupe Ramírez-Ledesma, Genaro Vázquez-Victorio, Rolando Hernández-Muñoz, Mauricio Díaz-Muñoz, and Francisco G. Vázquez-Cuevas. "Purinergic Signaling in Non-Parenchymal Liver Cells." International Journal of Molecular Sciences 25, no. 17 (2024): 9447. http://dx.doi.org/10.3390/ijms25179447.

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Purinergic signaling has emerged as an important paracrine–autocrine intercellular system that regulates physiological and pathological processes in practically all organs of the body. Although this system has been thoroughly defined since the nineties, recent research has made substantial advances regarding its role in aspects of liver physiology. However, most studies have mainly targeted the entire organ, 70% of which is made up of parenchymal cells or hepatocytes. Because of its physiological role, the liver is exposed to toxic metabolites, such as xenobiotics, drugs, and fatty acids, as w

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García, Mauricio A., Felipe Varum, Jozef Al-Gousous, Michael Hofmann, Susanne Page, and Peter Langguth. "In Vitro Methodologies for Evaluating Colon-Targeted Pharmaceutical Products and Industry Perspectives for Their Applications." Pharmaceutics 14, no. 2 (2022): 291. http://dx.doi.org/10.3390/pharmaceutics14020291.

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Several locally acting colon-targeted products to treat colonic diseases have been recently developed and marketed, taking advantage of gastrointestinal physiology to target delivery. Main mechanisms involve pH-dependent, time-controlled and/or enzymatic-triggered release. With site of action located before systemic circulation and troublesome colonic sampling, there is room for the introduction of meaningful in vitro methods for development, quality control (QC) and regulatory applications of these formulations. A one-size-fits-all method seems unrealistic, as the selection of experimental co

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Henderson, Brian, and Andrew C. R. Martin. "Protein moonlighting: a new factor in biology and medicine." Biochemical Society Transactions 42, no. 6 (2014): 1671–78. http://dx.doi.org/10.1042/bst20140273.

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The phenomenon of protein moonlighting was discovered in the 1980s and 1990s, and the current definition of what constitutes a moonlighting protein was provided at the end of the 1990s. Since this time, several hundred moonlighting proteins have been identified in all three domains of life, and the rate of discovery is accelerating as the importance of protein moonlighting in biology and medicine becomes apparent. The recent re-evaluation of the number of protein-coding genes in the human genome (approximately 19000) is one reason for believing that protein moonlighting may be a more general p

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Gubergrits, N. B., N. V. Byelyayeva, A. Y. Klochov, et al. "Halitosis syndrome in clinical practice." Herald of Pancreatic Club 42, no. 1 (2019): 73–77. http://dx.doi.org/10.33149/vkp.2019.01.10.

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Definition of the medical term “halitosis” is presented in the article, historical aspects of its appearance are reviewed, probable prevalence of halitosis in the general population is indicated. Classification of halitosis with the allocation of its subtypes depending on the conditions of occurrence is given, the reasons for the development of true and false, physiological and pathological halitosis are analyzed. Various nosological items and pathological conditions are listed, the course of which may be accompanied by the appearance of bad breath. The influence of the emotional background on

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Zhuk, S. I., O. D. Shchurevska, and V. M. Yefisko. "Role of prenatal microbiota in fetal programming." REPRODUCTIVE ENDOCRINOLOGY, no. 66 (August 10, 2022): 32–38. http://dx.doi.org/10.18370/2309-4117.2022.66.32-38.

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According to the concept of D. Barker, the intrauterine period is decisive in the programming of postnatal pathology, which can manifest during life. Among the factors of fetal programming, the microbiota plays an important role, but many aspects are still debatable.Objective: analysis and generalization of literary data devoted to the study of the association between the human body and microorganisms, their characteristics during pregnancy and their role in the health and pathology.According to the literature analysis, the article provides data on the non-sterility of the intrauterine environ

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Silva, Renata da Costa Barros, Jéssica Andrade, Vanessa Cordeiro Dias, et al. "Physiological Characteristics of Putative Enterobacteria Associated with Meat and Fish Available in Southern Brazilian Retail Markets: Antimicrobial Susceptibility, Toxic Metal Tolerance and Expression of Efflux Pumps." Antibiotics 11, no. 12 (2022): 1677. http://dx.doi.org/10.3390/antibiotics11121677.

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Multidrug-resistant (MDR) mesophilic facultatively anaerobic Gram-negative rods are a public health issue and their spread from animal-source foods to humans is of concern worldwide. Hence, the aim of this study was to examine the antibiotic susceptibility patterns and physiological aspects of such rods, including their tolerance to toxic metals and the screening of efflux pumps expressing isolates among enterobacteria isolated from meat (chicken, beef and pork) and fish samples acquired from retail establishments in a Brazilian urban Centre of over 2,300,000 inhabitants. The study revealed th

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S.I., Zhuk, Shchurevska O.D., and Yefisko V.M. "Role of prenatal microbiota in fetal programming." REPRODUCTIVE ENDOCRINOLOGY, no. 66 (August 10, 2022): 32–38. https://doi.org/10.18370/2309-4117.2022.66.32-38.

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According to the concept of D. Barker, the intrauterine period is decisive in the programming of postnatal pathology, which can manifest during life. Among the factors of fetal programming, the microbiota plays an important role, but many aspects are still debatable. <strong>Objective:</strong> analysis and generalization of literary data devoted to the study of the association between the human body and microorganisms, their characteristics during pregnancy and their role in the health and pathology. According to the literature analysis, the article provides data on the non-sterility of

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Rojas-Valverde, Daniel, Diego A. Bonilla, Luis M. Gómez-Miranda, Juan J. Calleja-Núñez, Natalia Arias, and Ismael Martínez-Guardado. "Examining the Interaction between Exercise, Gut Microbiota, and Neurodegeneration: Future Research Directions." Biomedicines 11, no. 8 (2023): 2267. http://dx.doi.org/10.3390/biomedicines11082267.

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Physical activity has been demonstrated to have a significant impact on gut microbial diversity and function. Emerging research has revealed certain aspects of the complex interactions between the gut, exercise, microbiota, and neurodegenerative diseases, suggesting that changes in gut microbial diversity and metabolic function may have an impact on the onset and progression of neurological conditions. This study aimed to review the current literature from several databases until 1 June 2023 (PubMed/MEDLINE, Web of Science, and Google Scholar) on the interplay between the gut, physical exercis

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Moccia, Valentina, Alessandro Sammarco, Laura Cavicchioli, Massimo Castagnaro, Laura Bongiovanni, and Valentina Zappulli. "Extracellular Vesicles in Veterinary Medicine." Animals 12, no. 19 (2022): 2716. http://dx.doi.org/10.3390/ani12192716.

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Extracellular vesicles (EVs) are cell-derived membrane-bound vesicles involved in many physiological and pathological processes not only in humans but also in all the organisms of the eukaryotic and prokaryotic kingdoms. EV shedding constitutes a fundamental universal mechanism of intra-kingdom and inter-kingdom intercellular communication. A tremendous increase of interest in EVs has therefore grown in the last decades, mainly in humans, but progressively also in animals, parasites, and bacteria. With the present review, we aim to summarize the current status of the EV research on domestic an

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Bollapragada, Mani Kumar, Manjula Shantaram, and Sunil Kumar R. "OBESITY: DEVELOPMENT, EPIDEMIOLOGY, FACTORS AFFECTING, QUANTITY, HEALTH HAZARDS, MANAGEMENT AND NATURAL TREATMENT-A REVIEW." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 2 (2017): 12. http://dx.doi.org/10.22159/ijpps.2017v9i2.15049.

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<p>Due to the advancement in science, enhanced knowledge on the physiological aspects of almost all the tissues and the organs of the human body is gained. One of the most important prevalent topics needed for discussion is obesity and its effect on the metabolic changes leading to disorders in the human body such as diabetes, hypertension, cardiovascular diseases in addition to chronic diseases such as stroke, osteoarthritis, sleep apnea, some cancers, and inflammation-based pathologies. In recent years, obesity is a serious socioeconomic issue, which has become one of the major health

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Beniwal, Rahul, Radheshyam Yadav, and Wusirika Ramakrishna. "Multifarious Effects of Arsenic on Plants and Strategies for Mitigation." Agriculture 13, no. 2 (2023): 401. http://dx.doi.org/10.3390/agriculture13020401.

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Arsenic contamination in soil and water is a major problem worldwide. Inorganic arsenic is widely present as arsenate and arsenite. Arsenic is transferred to crops through the soil and irrigation water. It is reported to reduce crop production in plants and can cause a wide array of diseases in humans, including different types of cancers, premature delivery, stillbirth, and spontaneous abortion. Arsenic methyltransferase (AS3MT) in the human body converts inorganic arsenic into monomethylarsonic acid and dimethylarsinic acid, which are later excreted from the body. Arsenic transfer from the s

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Andriushchenko, V. P. "Acute purulent widespread peritonitis: conceptual aspects of modern surgical tactics." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 7–9. http://dx.doi.org/10.32902/2663-0338-2020-3.2-7-9.

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Background. The priority areas of the problem of acute widespread peritonitis (AWP) include the standardization of terminology and classification, assessment of the severity of the process, control of the infection source and correction of pathological intra-abdominal syndromes. Objective. To outline the conceptual aspects of AWP surgical treatment based on consensus guidelines and own research. Materials and methods. The study involved 371 patients with AWP. Patients underwent the necessary clinical, laboratory, biochemical, bacteriological, radiological, instrumental and pathomor

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Fong, Karen P., Whasun O. Chung, Richard J. Lamont, and Donald R. Demuth. "Intra- and Interspecies Regulation of Gene Expression by Actinobacillus actinomycetemcomitansLuxS." Infection and Immunity 69, no. 12 (2001): 7625–34. http://dx.doi.org/10.1128/iai.69.12.7625-7634.2001.

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ABSTRACT The cell density-dependent control of gene expression is employed by many bacteria for regulating a variety of physiological functions, including the generation of bioluminescence, sporulation, formation of biofilms, and the expression of virulence factors. Although periodontal organisms do not appear to secrete acyl-homoserine lactone signals, several species, e.g., Porphyromonas gingivalis,Prevotella intermedia, and Fusobacterium nucleatum, have recently been shown to secrete a signal related to the autoinducer II (AI-2) of the signal system 2 pathway inVibrio harveyi. Here, we repo

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Vasilache, Eugenia, Ion Arteni, Lucia Turcan, and Nicolae Bacinschi. "The particularities of antibacterial treatment in nosocomial pneumonia in patients with comorbidities." Public Health, Economy and Management in Medicine, no. 4(101) (October 2024): 55–62. https://doi.org/10.52556/2587-3873.2024.4(101).09.

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Nosocomial pneumonia is one of the causes of medical complications and deaths among patients hospitalized in medical institution. The significant use of antibacterials and the causes of failure of antibiotic therapy of nosocomial pneumonia require continuous reevaluation and detailed approach. The study was analytical, retrospective based on 45 medical records of patients with nosocomial pneumonia treated in the „Gheorghe Paladi” Municipal Clinical Hospital. Th e analysis of medical records determined the prevalence of nosocomial pneumonia in the elderly with the predominance of pneumonia asso

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Denis, Marie-Claude, Denis Roy, Pantea Rahmani Yeganeh, et al. "Apple peel polyphenols: a key player in the prevention and treatment of experimental inflammatory bowel disease." Clinical Science 130, no. 23 (2016): 2217–37. http://dx.doi.org/10.1042/cs20160524.

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Diets rich in fruits and vegetables may reduce oxidative stress (OxS) and inflammation via several mechanisms. These beneficial effects may be due to their high polyphenol content. The aims of the present study are to evaluate the preventive and therapeutic aspects of polyphenols in dried apple peel powder (DAPP) on intestinal inflammation while elucidating the underlying mechanisms and clinical benefits. Induction of intestinal inflammation in mice was performed by oral administration of the inflammatory agent dextran sulfate sodium (DSS) at 2.5% for 10 days. Physiological and supraphysiologi

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Cazzaniga, Massimiliano, Marco Cardinali, Francesco Di Pierro, et al. "The Role of Short-Chain Fatty Acids, Particularly Butyrate, in Oncological Immunotherapy with Checkpoint Inhibitors: The Effectiveness of Complementary Treatment with Clostridium butyricum 588." Microorganisms 12, no. 6 (2024): 1235. http://dx.doi.org/10.3390/microorganisms12061235.

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The discovery of immune checkpoints (CTLA-4, PD-1, and PD-L1) and their impact on the prognosis of oncological diseases have paved the way for the development of revolutionary oncological treatments. These treatments do not combat tumors with drugs “against” cancer cells but rather support and enhance the ability of the immune system to respond directly to tumor growth by attacking the cancer cells with lymphocytes. It has now been widely demonstrated that the presence of an adequate immune response, essentially represented by the number of TILs (tumor-infiltrating lymphocytes) present in the

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Soni, Neetu, Rashmi Pradhan, and Bhupendra Kumar Mishra. "PHYSIOLOGICAL ASPECTS OF ASTHIDHATU." International Ayurvedic Medical Journal 9, no. 10 (2021): 2495–99. http://dx.doi.org/10.46607/iamj3209102021.

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Ayurveda is an ancient medical science which is related to health. Ayurveda described three basic physiological constitution of the body they are: Dosha, Dhatu and mala. Dhatu are structural unit of the body. Asthi is fifth dhatu among saptadhatu. In modern science asthidhatu relate with bones and cartilage. Bones store minerals such as calcium. Metabolic bone diseases are caused by minerals and vitamins deficiency. Asthidhatu is resultant of action of medoagni on medodhatu and is responsible for nourishing majjadhatu. It supports the basic structures, protect vital organs, nourishing the nerv

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Tempest, D. W., and O. M. Neijssel. "Physiological and energetic aspects of bacterial metabolite overproduction." FEMS Microbiology Letters 100, no. 1-3 (1992): 169–70. http://dx.doi.org/10.1111/j.1574-6968.1992.tb05699.x.

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Gounot, Anne-Monique. "Bacterial life at low temperature: physiological aspects and biotechnological implications." Journal of Applied Bacteriology 71, no. 5 (1991): 386–97. http://dx.doi.org/10.1111/j.1365-2672.1991.tb03806.x.

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Bisno, Alan L. "Molecular Aspects of Bacterial Colonization." Infection Control and Hospital Epidemiology 16, no. 11 (1995): 648–57. http://dx.doi.org/10.2307/30141119.

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Bisno, Alan L. "Molecular Aspects of Bacterial Colonization." Infection Control and Hospital Epidemiology 16, no. 11 (1995): 648–57. http://dx.doi.org/10.1086/647032.

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Pfeufer, Emily E., and Beth K. Gugino. "Environmental and Management Factors Associated with Bacterial Diseases of Onion in Pennsylvania." Plant Disease 102, no. 11 (2018): 2205–11. http://dx.doi.org/10.1094/pdis-11-17-1703-re.

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Bacterial diseases of onion may result in over 60% yield loss in crops grown in the Mid-Atlantic region, even when managed with recommended chemical and cultural practices. To identify environmental and production factors associated with the high incidence of bacterial rots in Pennsylvania, data on 32 environmental and management variables ranging from soil temperature to foliar nutrients were recorded during three visits to each of 28 and 26 fields, surveyed in 2011 and 2012, respectively. Multiple linear regression indicated negative relationships between foliar nitrogen and carbon at midsea

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Gulbins, Erich, and Pin Lan Li. "Physiological and pathophysiological aspects of ceramide." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 290, no. 1 (2006): R11—R26. http://dx.doi.org/10.1152/ajpregu.00416.2005.

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Activation of cells by receptor- and nonreceptor-mediated stimuli not only requires a change in the activity of signaling proteins but also requires a reorganization of the topology of the signalosom in the cell. The cell membrane contains distinct domains, rafts that serve the spatial organization of signaling molecules in the cell. Many receptors or stress stimuli transform rafts by the generation of ceramide. These stimuli activate the acid sphingomyelinase and induce a translocation of this enzyme onto the extracellular leaflet of the cell membrane. Surface acid sphingomyelinase generates

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Alasadi, Fatima Karim Khudair, Hadeel Mohammed Thabit, and Safa Amer. "Effect of Bacterial Diseases on the Physiological Functions of the Plant: A Review." European Journal of Theoretical and Applied Sciences 2, no. 3 (2024): 1056–61. http://dx.doi.org/10.59324/ejtas.2024.2(3).84.

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Physiological plant diseases are illnesses that affect plants and are classified as Infectious Plant Diseases and Noninfectious Plant Diseases. They are brought on by disturbance and imbalance in the physiological processes of the plant. The study of the mechanisms underlying the occurrence of these damages becomes connected to the defect incident physiology. In the context of this review, environmental physiology refers to the study of how plants react to their surroundings and change as a result of disease infection.

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T M, Nandan, Veena C N, and Shiva Murthy N. "Physiological Aspects Responsible For Mucormycosis Outbreak." Biomedicine 44, no. 2 (2024): 184–89. https://doi.org/10.51248/v44i2.26.

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Here in this article, we provide an overview of related terminologies, physiological factors and their mechanisms responsible for outbreak of mucormycosis. Mucormycosis indicate diseases caused by many non-septate filamentous fungal species earlier designated under mucorales and entomophthorales. Being present everywhere in soil, mucormycosis is exceptionally prevalent in waterlogged soil, putrescent plants and foods, excreta of birds and animals, air water surrounding the buildings. Diverse set of exposures such as rise in the incidence of diabetes, immunosuppressant use and trial prophylaxis

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Fatima, Karim Khudair Alasadi, Mohammed Thabit Hadeel, and Amer Safa. "Effect of Bacterial Diseases on the Physiological Functions of the Plant: A Review." European Journal of Theoretical and Applied Sciences 2, no. 3 (2024): 1056–61. https://doi.org/10.59324/ejtas.2024.2(3).84.

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Physiological plant diseases are illnesses that affect plants and are classified as Infectious Plant Diseases and Noninfectious Plant Diseases. They are brought on by disturbance and imbalance in the physiological processes of the plant. The study of the mechanisms underlying the occurrence of these damages becomes connected to the defect incident physiology. In the context of this review, environmental physiology refers to the study of how plants react to their surroundings and change as a result of disease infection. 

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