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Journal articles on the topic 'Physostigma'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Sunday, R. M. "Medicinal Properties and Toxic Effects of the Seeds of Abrus precatorius, Datura metel, Physostigma venenosum and Ricinus communis used in Ethnomedicine in Nigeria: A Review." Journal of Applied Sciences and Environmental Management 28, no. 7 (2024): 2173–84. http://dx.doi.org/10.4314/jasem.v28i7.31.

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Plants with medicinal properties are used all over the world for disease treatment. Poisonous phytochemicals (toxins) in some or all parts of these medicinal plants are the causeof the toxic effects exerted by some medicinal plants. The objective of this paper is to provide a review on themedicinal effects and toxic properties of the seeds of some medicinal plants (Abrus precatorius, Datura metel, Physostigma venenosum and Ricinus communis) used in ethnomedicine in Nigeria by harvesting secondary data from standard online sources. This review gives collective reports on the medicinal propertie

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2

ZHAO, B., S. MOOCHHALA, and S. THAM. "Biologically active components of Physostigma venenosum." Journal of Chromatography B 812, no. 1-2 (2004): 183–92. http://dx.doi.org/10.1016/s1570-0232(04)00677-4.

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3

Batiha, Gaber El-Saber, Luay M. Alkazmi, Eman H. Nadwa, et al. "Physostigmine: A Plant Alkaloid Isolated from Physostigma venenosum: A Review on Pharmacokinetics, Pharmacological and Toxicological Activities." Journal of Drug Delivery and Therapeutics 10, no. 1-s (2020): 187–90. http://dx.doi.org/10.22270/jddt.v10i1-s.3866.

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Medicinal plants have been documented as an important source for discovering new pharmaceutical molecules that have been used to treat serious diseases. Strikingly, previous reports stated that natural products and their derived compounds exhibit lesser side effects and improved efficacy than other synthetic counterparts. Physostigmine, a parasympathomimetic plant alkaloid isolated from the West African perennial shrub Physostigma venenosum, it shows a narrow therapeutic index and a short life span, despite its ability to penetrate the blood-brain barrier (BBB). It is a widely known reversible

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4

Ovuakporie-Uvo, O. "Histopathological Studies of Physostigma venenosum Balf. on Wistar Rats." J. of Advanced Botany and Zoology 7, no. 1 (2019): 04. https://doi.org/10.5281/zenodo.2573795.

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<em>Physostigma venenosum</em> Balf. seeds which have been implicated for treating diverse ailments were investigated for possible toxicity of the liver in both sexes of Wistar rats. Sixteen Wistar were weighed and divided into four groups of three treatment groups and one control group. Animals were allowed to acclimatize in standard metal cages for 7 days thereafter, fed with graded doses of <em>P. venenosum</em> extract. Group A (control) was administered 10 mg/kg distilled water only, while groups B, C and D were respectively administered with 10, 20 and 30 mg/kg b.w of <em>P. venenosum</e

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5

Bull, E., and C. Ikpa. "Isolation, characterisation and anti-cholinesterase activities of Physostigma venenosum (Calabar bean)." American Journal of Scientific and Industrial Research 4, no. 2 (2013): 226–30. http://dx.doi.org/10.5251/ajsir.2013.4.2.226.230.

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6

Suresh, S., L. Ganesh, and S. Manonmani. "Pilot study on ultra high dilution of physostigma venenosum for accommodation error-myopia." Allgemeine Homöopathische Zeitung 262, no. 02 (2017): 2–76. http://dx.doi.org/10.1055/s-0037-1601216.

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7

Archibong, Boniface Effiong, Simon Idoko Okweche, Idorenyin Asukwo Udo, and Sylvia Bassey Umoetok. "Fumigant and Repellence Potentials of Oils from Four Plant species Against Sitophilus zeamais Motschulsky (Coleóptera: Curculionidae)." Nigerian Journal of Entomology 41, no. 1 (2025): 125–41. https://doi.org/10.36108/nje/5202/14.0190.

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Insect pests infestation is one the major problems associated with the production of maize in many Sub-Saharan Africa including Nigeria. Control of these pests by farmers has been vastly through the use of synthethic chemical pesticide which possesses lots of threats to human health and environments. A study was conducted at the University of Calabar, Nigeria, to assess the effectiveness of essential oils (EOs) derived from four plant species against Sitophilus zeamais Motschulsky, commonly known as the maize weevil. The EOs were applied in varying concentrations (2.5, 5, 7.5, and 10 µl/l) arr

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8

Witkop, Bernhard. "From the "Ordeal Bean" (Physostigma venenosum) to the Ordeal of Alzheimer's Disease ----- Some of the Legacy of Percy Lavon Julian (1899 - 1975)." HETEROCYCLES 49, no. 1 (1998): 9. http://dx.doi.org/10.3987/1998-01-0009.

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9

Witkop, Bernhard. "ChemInform Abstract: From the “Ordeal Bean” (Physostigma venenosum) to the Ordeal of Alzheimer′s Disease - Some of the Legacy of Percy Lavon Julian." ChemInform 30, no. 18 (2010): no. http://dx.doi.org/10.1002/chin.199918240.

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10

Robinson, Brian. "ChemInform Abstract: Alkaloids of Physostigma venenosum. Part 12. Syntheses of (-)-Physostigmine, with Particular Emphasis upon the Clarification of Two Enigmatic Early Synthetic Approaches." ChemInform 33, no. 40 (2010): no. http://dx.doi.org/10.1002/chin.200240284.

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11

Obi, Juliet O., Anthony C. Ikeme, Patrick E. Nwakama, and Ashiwel S. Undieh. "The Calabar bean and physostigmine: from African ethno-jurisprudence to medicinal discovery and modern pharmacotherapeutics." American Journal of Pharmacotherapy and Pharmaceutical Sciences 2 (February 28, 2023): 1. http://dx.doi.org/10.25259/ajpps_2023_001.

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Physostigmine, or eserine, is an alkaloid found in the Calabar bean (eséré), Physostigma venenosum (Balfour). The scientific discovery of physostigmine played a pivotal role in our understanding of chemical neurotransmission and the emergence of pharmacology as a science. The Efik people of Old Calabar, in present day Cross River State of Nigeria, used the bean as an ordeal poison to determine if persons accused of certain allegations such as witchcraft were guilty or innocent. Scottish missionaries working in Old Calabar witnessed eséré ordeal trials and attended to patients inadvertently poi

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12

Rył, Bartosz, and Izabela Jasicka-Misiak. "POTENCJAŁ ZASTOSOWANIA FITOZWIĄZKÓW Z DZIKOROSNĄCYCH ROŚLIN ZIELNYCH W PREWENCJI I TERAPII WYBRANYCH CHORÓB CYWILIZACYJNYCH." Wiadomości Chemiczne 78, no. 5 (2024): 625–50. https://doi.org/10.53584/wiadchem.2024.05.10.

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The prevalence of individual civilisational diseases has been constantly increasing in recent years. Their occurrence is related, among other factors, to changes in lifestyle (stress, low levels of physical activity, low-quality diet), increasing urbanisation and industrialisation (environmental pollution). Lifestyle- dependent diseases include type 2 diabetes and Alzheimer's disease which is not only related to lifestyle - one of the main risk factors is age. The increasing life expectancy of the population associated with the development of civilisation (health, social and welfare) therefore

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13

Coelho Filho and Birks. "Physostigmin bei Morbus Alzheimer." Praxis 91, no. 29 (2002): 1211–12. http://dx.doi.org/10.1024/0369-8394.91.29.1211.

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14

Haase, Ulrike, and Ingrid Rundshagen. "Pharmakotherapie - Physostigmin post OP." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 42, no. 3 (2007): 188–89. http://dx.doi.org/10.1055/s-2007-974580.

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15

Hüser, Christoph, Gerald Hackl, and Matthias Baumgärtel. "Update – Intoxikationen in der Intensivmedizin." DMW - Deutsche Medizinische Wochenschrift 145, no. 03 (2020): 161–65. http://dx.doi.org/10.1055/a-0965-3203.

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Was ist neu? Intoxikationen mit Betablockern und Kalziumantagonisten Es gibt eine Experten-Konsensus-Empfehlung für die Intoxikation mit Kalziumantagonisten. Diese kann zum Teil auch auf Betablocker-Intoxikationen übertragen werden. Die Verwendung von hochdosiertem Insulin sowie von Lipidemulsionen wird empfohlen. Des Weiteren soll der Einsatz einer VA-ECMO bei diesen Intoxikationen erwogen werden. Paracetamol-Intoxikationen Bei Einnahme einer größeren Menge Paracetamol sollte die Gabe einer höheren Acetylcystein-Dosis als im ursprünglichen von Prescott vorgeschlagenen Schema überlegt werden.

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16

Hartung, H. J., P. Osswald, R. Puhl, and R. Jacoby. "Beeinflussung der postoperativen Somnolenz nach Halothananästhesie durch Physostigmin." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 21, no. 02 (1986): 82–84. http://dx.doi.org/10.1055/s-2007-1002452.

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17

Schneck, H., G. Tempel, and B. v. Hundelshausen. "Medikamentöse Beeinflussung der Vigilanz in der postnarkotischen Phase - Naloxone oder Physostigmin?" AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 23, no. 04 (1988): 209–13. http://dx.doi.org/10.1055/s-2007-1001620.

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18

Seitz, R., M. Wehr, and N. Pallmert. "Arrhythmien bei Vergiftung durch trizyklische Antidepressiva: Erfolgreiche Behandlung mit Physostigmin und Natrium." DMW - Deutsche Medizinische Wochenschrift 107, no. 28 (2008): 1096–99. http://dx.doi.org/10.1055/s-2008-1070081.

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19

Krull, F., and A. Risse. "Ein Fall von malignem neuroleptischem Syndrom mit Rhabdomyolyse und Therapieversuch mit Physostigmin." Fortschritte der Neurologie · Psychiatrie 54, no. 12 (1986): 398–401. http://dx.doi.org/10.1055/s-2007-1001945.

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20

Blockmans, D., and O. Steeno. "Physostigmine as a Treatment for Anejaeulation with Paraplegic Men/Physostigmin als Behandlung bei Anejakulation infolge Paraplegie." Andrologia 20, no. 4 (2009): 311–13. http://dx.doi.org/10.1111/j.1439-0272.1988.tb00692.x.

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21

Lauven, P. "Bericht über das 2. Symposium „Das zentrale anticholinergische Syndrom: Physostigmin in der Intensivmedizin -Anästhesiologie -Psychiatrie” in Bonn." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 20, no. 05 (1985): 291–93. http://dx.doi.org/10.1055/s-2007-1003128.

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22

Kuznetsov, Sergey V., Nataliya N. Kuznetsova, and Polina A. Gaydukova. "Influence of l-type slow calcium channels blockers on cardiac, respiratory and motor activity at the intact and poisoned by physostigmine (eserine) of rats during the early ontogeny." Reviews on Clinical Pharmacology and Drug Therapy 17, no. 3 (2019): 39–49. http://dx.doi.org/10.17816/rcf17339-49.

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The effects of calcium-channel blockers (CCBs) (verapamil, nifedipine) on heart rate, respiration rate and motor activity were studied in 3-30-day-old rats. The role of calcium channels in development of disturbances of a heart and respiratory rhythms after introduction to newborn rats of acetylcholinesterase (AChE) inhibitor of physostigmine was revealed. Parameters of functional activity of heart, respiratory and somatomotor systems in case of blockade of calcium channels were studied also under conditions of the activation of cholinoceptive structures caused by an injection to infant rats o

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23

"Physostigma venenosum." CABI Compendium CABI Compendium (January 7, 2022). http://dx.doi.org/10.1079/cabicompendium.30803016.

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24

"Isolation and Characterization of Colchicine from Physostigma Venenosium." IOSR Journal of Applied Chemistry 5, no. 6 (2013): 51–54. http://dx.doi.org/10.9790/5736-0565154.

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25

Horton, Dasha M., Yonas Feleke, Remy S. Pasquet, et al. "Phylogenetic systematics of Vigna sensu stricto in the context of Physostigma and allies." American Journal of Botany, August 6, 2024. http://dx.doi.org/10.1002/ajb2.16381.

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AbstractPremiseVigna includes economically vital crops and wild species. Molecular systematic studies of Vigna species resulted in generic segregates of many New World (NW) species. However, limited Old World (OW) sampling left questions regarding inter‐ and intraspecific relationships in Vigna s.s.MethodsAfrican species, including the putative sister genus Physostigma, were comprehensively sampled within the context of NW relatives. Maximum likelihood and Bayesian inference analyses of the chloroplast matK‐trnK and nuclear ribosomal ITS/5.8 S (ITS) DNA regions were undertaken to resolve OW Vi

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26

Yu, Erika, Shloka Raghavan, Shreya Anand, et al. "Modular mimics of neuroactive alkaloids - design, synthesis, and cholinesterase inhibitory activity of rivastigmine analogs." Journal of Emerging Investigators, 2022. http://dx.doi.org/10.59720/22-070.

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The treatment of neurological diseases has evolved to include neuroactive alkaloids isolated from naturally occurring phytochemical sources. While some of these compounds have gone on to clinical use themselves, others have inspired the development of synthetic analogs, which might possess greater potency or better pharmacological features than the natural product itself. One such naturally occurring alkaloid, physostigmine, which is found in the Calabar bean plant Physostigma venenosum, has been demonstrated to be a potent cholinesterase inhibitor. However, some of physostigmine's characteris

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27

Jee, Krishna, Rishabh Gaur, Jai Prakash Kadian, et al. "A Review on Phytochemical Constituents Used as Current Treatment Strategies for Neurodegenerative Disease." Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 25 (October 16, 2024). http://dx.doi.org/10.2174/0118715230310192240925165925.

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Abstract: In today’s time, a diversity of neurodegenerative diseases that widely affect the CNS causing insufficiency in particular brain processes such as memory, mobility, and cognition due to the moderate loss of CNS neurons. This review emphasizes different phytochemical constituents used widely for the prevention or treatment of various neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkin-son’s disease (PD). Berberin (BBR), which is an isoquinoline class of alkaloid and isolated from the plant Hydrastis condenses and Berberis aaristata, has both acetylcholine esterase (A

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28

"Routinemäßige Gabe von Physostigmin hat für die postoperative Phase keine Bedeutung." ains · Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 38, no. 8 (2003): 528–37. http://dx.doi.org/10.1055/s-2003-41184.

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29

HASGÜL, Burak, Merve ÇATAK, Arif İsmet ÇATAK, and Serhat KARAMAN. "CASE SERİES WITH ATROPA BELLADONNA (DEADLY NIGHTSHADE) INTOXICATION AND EXPERIENCE OF PHYSOSTIGMIN." Journal of Emergency Medicine Case Reports, November 29, 2021. http://dx.doi.org/10.33706/jemcr.998002.

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