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1

Ankli, Anita Sabine. "Yucatec Mayan medicinal plants : ethnobotany, biological evaluation and phytochemical study of Crossopetalum gaumeri." [S.l.] : [s.n.], 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13555.

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Uche, Fidelia Ijeoma. "Phytochemical analysis and evaluation of anticancer and antimalarial properties of four medicinal plants." Thesis, Keele University, 2017. http://eprints.keele.ac.uk/3080/.

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Cancer and malaria are among the most life-threatening diseases globally. Cancer is responsible for about 125,000 annual deaths globally. In 2015, the World Health Organization report estimated that 236000-635000 people died of malaria. These diseases are complicated by the development of resistance to available chemotherapeutic agents. Natural products have been recognized for their major applications in the identification of drug leads in drug discovery. Viola philippica Car, Viola yedoensis Makino (Violaceae), Triclisia subcordata Oliv (Menispermeaceae) and Cyclicodiscus gabunensis Harms (F
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Bueno, Perez Lynette. "Phytochemical and Biological Evaluation of Two Vietnamese Plants, Indigofera spicata and Millettia caerulea." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1402256396.

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Richmond, Oliver H. III. "Extraction, Purification and Evaluation of PRMT5-Inhibitory Phytochemical Compounds for the Treatment of Prostate Adenocarcinoma." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2019. http://digitalcommons.auctr.edu/cauetds/185.

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The development and advancement of prostate cancer is supported by a plethora of genetic and proteomic abnormalities, including events of post-translational modifications. The protein arginine methyltransferase 5 (PRMT5) enzyme regulates epigenetic events of histone modifications and protein post-translational modifications within protein signaling pathways. PRMT5 functions by catalyzing the symmetric dimethylation of terminal arginine residues on target protein substrates. Under abnormal conditions of overexpression and upregulation, PRMT5 methyltransferase activity constitutively drives the
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Joshi, Prabesh. "SUPERVISED CLASSIFICATION OF FRESH LEAFY GREENS AND PREDICTION OF THEIR PHYTOCHEMICAL CONTENTS USING NEAR INFRARED REFLECTANCE." OpenSIUC, 2018. https://opensiuc.lib.siu.edu/theses/2467.

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There is an increasing need of automation for routine tasks like sorting agricultural produce in large scale post-harvest processing. Among different kinds of sensors used for such automation tasks, near-infrared (NIR) technology provides a rapid and effective solution for quantitative analysis of quality indices in food products. As industries and farms are adopting modern data-driven technologies, there is a need for evaluation of the modelling tools to find the optimal solutions for problem solving. This study aims to understand the process of evaluation of the modelling tools, in view of n
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Loonat, Firdows. "Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/4379.

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Magister Pharmaceuticae - MPharm<br>Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western Cape Ruta graveolens (Rutaceae) L. is a medicinal plant that is commonly used to manage and treat essential events such as pain, inflammation and fever. Despite its popularity, particularly as a medicinal plant in the Calvinia district and Bredasdorp region of South Africa, scientific data to substantiate its widespread traditional use and
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Bwalya, A. G. "Evaluation of the in vitro biological activities and phytochemical profiling of eight Ficus species collected in Zambia." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1457111/.

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Infectious diseases are responsible for an overwhelming number of deaths and morbidity worldwide. In tropical regions of the world, in particular, developing countries like Zambia, poor health is prevalent and diseases such as malaria, meningitis, pneumonia, tuberculosis and gastrointestinal infections strongly persist. Folkloric medicines are still actively used against some of these infections as primary care before seeking conventional treatment at hospitals. Members of the genus Ficus (Moraceae) are traditionally used in Zambia against many diseases caused by bacterial, fungal and protozoa
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BUSA', Rosalia. "Evaluation of antitumor and immunomodulatory properties of Indicaxanthin from Opuntia Ficus Indica (L. Mill) fruit." Doctoral thesis, Università degli Studi di Palermo, 2020. http://hdl.handle.net/10447/395264.

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Cancer is a growing health problem around the world and according to estimates from the International Agency for Research on Cancer (IARC), 14.1 million new cancer cases and 8.2 million cancer deaths worldwide have been reported in 2012 (Ferlay et al., 2015). By 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Indicaxanthin ((2S)-2,3-dihydro-4-[2-[(2S)-2a-carboxypyrrolidin-1- yl]ethenyl]pyridine-2a,6-dicarboxylic acid), a betalain pigment from cactus pear fruit, has been the object o
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Obst, Katja [Verfasser], Karl-Heinz [Akademischer Betreuer] Engel, and Thomas [Akademischer Betreuer] Hofmann. "Phytochemical Characterization and Sensory Evaluation of Macropiper excelsum / Katja Obst. Gutachter: Karl-Heinz Engel ; Thomas Hofmann. Betreuer: Karl-Heinz Engel." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1068002247/34.

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Deliwe, Mzonke. "Pharmacological evaluation of antidiarrhoeal and antidiabetic activities of Syzygium Cordatum Hochst. ex C. Krauss." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9985_1351170857.

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Syzygium cordatum is a medicinal plant indigenous to South Africa and Mozambique, commonly used to treat stomach aches, diabetes, respiratory problems and tuberculosis. In spite of the folklore use, adequate scientific data to credit its widespread traditional use is lacking. The objectives of this study were: to evaluate and validate scientifically the successful therapeutic claims by traditional medicine practitioners that Syzygium cordatum is effective in treating diarrhoea and diabetes<br>to determine the effects of the plant extract on gastrointestinal transit of a charcoal meal in mice<b
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Khan, Mohammed Taufiq. "Phytochemical and biological studies of Tagetes erecta and its clinical evaluation in the treatment of hallux abducto valgus and its associated condition, bunion." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325016.

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Kantamreddi, Venkata Siva Satya Narayana. "Evaluation of Indian medicinal plants used traditionally for the treatment of Malaria. Phytochemical investigation of Alangium lamarkii and Tarenna zeylanica for antiplasmodial and cytotoxic properties." Thesis, University of Bradford, 2008. http://hdl.handle.net/10454/4893.

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Despite decades of intense research, malaria remains a deadly worldwide disease. Resistance of Plasmodium falciparum to chemical treatment still remains important. Efforts are now being directed towards the discovery and development of new chemically diverse anti-malarial agents. In the course of the search for new antimalarial compounds, a study of plants traditionally used against malaria by the people inhabiting the forests located near Bhubaneswar, Orissa, India was made, which permitted the identification of 34 plants currently used. Among these, 27 plants were selected for testing for an
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Tankam, Joan Manjuh. "Pharmaceutical Potentials of Selected Aromatic Spices: Pharmacological and Phytochemical Evaluation of Cinnamon (Cinnamomum cassia), West African Black Pepper (Piper guineense) and Tree Basil (Ocimum gratissimum)." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188722.

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Gehrke, Ilaine Teresinha Seibel. "Estudo fitoquímico e biológico das espécies Schinus lentiscifolius, Schinus terebenhtifolius, Schinus molle e Schinus polygamus (Anacardiaceae) do RS." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/4216.

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The phytochemical and biological study of the species S. lentiscifolius, S. terebinthifolius, S. molle and S. polygamus known as ―aroeiras‖ (Anacardeaceae) distributed in Rio Grande do Sul, was carried out to establish the chemical composition of volatile oils obtained by hydrodistillation of aerial parts of leaves, flowers and fruits collected in different seasons. In addition, leaves and fruits were analyzed and compared to determine seasonal variations in the oils constitution. The oils chemical composition was determined by Gas Chromatography coupled with a Mass Spectrometry (GC-MS). The y
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Mbeng, Wilfred Otang. "Antifugal evaluation and phytochemical analysis of selected medicinal plants used in the treatment of fungal diseases associated with HIV infection in the Eastern Cape Province, South Africa." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1006834.

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Background. As a result of the AIDS pandemic, many people areimmuno compromised andopportunistic fungal infections (OFIs) such as candidiasis are common. Despite the widespread use of medicinal plants in South Africa, there is a dearth of knowledge regarding the use of such plants in the management of these infections. This study evaluates three South African medicinal plants (Arctotis arctotoides, Pittosporum viridiflorum, and Gasteria bicolor) traditionally used in the treatment of OFIs in HIV/AIDS patients, in the Eastern Cape Province, South Africa. Materials and methods. A six-stage proce
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Juan-Badaturuge, Malindra. "Antioxidant activity and phytochemical evaluations of selected medicinal plants." Thesis, University of Greenwich, 2010. http://gala.gre.ac.uk/8098/.

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The methanolic crude extract of aerial parts of the plant Scrophularia nodosa was shown to have potent DPPH radical scavenging activity (IC50 = 48.75 ± 7.00 μg/ml). Activity-guided fractionation resulted in the isolation of three principal antioxidant compounds; acteoside, angoroside C and angoroside A. Acteoside (yield = 1.21%, IC50 = 15.2 μM) appeared to be the most abundant and most antioxidant-active. The potent antioxidant activity is in support of the traditional use of the plant for wound healing and anti-inflammatory conditions. The methanolic extract of aerial parts of Tanacetum vulga
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DE, LUCIA DANIELA. "Phytochemicals: Design, Synthesis, Biological Evaluation and Novel Characterisation Methods." Doctoral thesis, Università degli studi di Ferrara, 2015. http://hdl.handle.net/11392/2487876.

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Talag, Agela Hussain Mohammed. "Phytochemical investigation and biological activities of Sanicula europaea and Teucrium davaeanum : isolation and identification of some constituents of Sanicula europaea and Teucrium davaeanum and evaluation of the antioxidant activity of ethanolic extracts of both plants and cytotoxic activity of some isolated compounds." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14482.

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The aim of this research was to investigate the phytochemistry of two species Sanicula europaea and Teucrium davaeanum which are traditionally used in treatment of wounds. Four compounds were isolated from the 80% methanolic extract of S. europaea; bis-(2-ethylhexyl) phthalate (1), palmitic acid (2), rosmarinic acid (3), saniculoside N (4). Compounds 1 and 2 were isolated for the first time from this species. The structure elucidation of the isolated compounds was on the basis of 1D, 2D NMR spectroscopy and mass spectrometry measurements. Two compounds were isolated from the crude glycosides e
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Mendes, Nuno Eduardo dos Anjos Serra. "Evaluation of different natural ingredients as satiety inductors." Master's thesis, Faculdade de Ciências e Tecnologia, 2012. http://hdl.handle.net/10362/8056.

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Dissertation to obtain a Master’s Degree in Chemical and Biochemical Engineering<br>Using natural ingredients to combat obesity has emerged as a promising alternative to conventional therapies which present many side effects. Satiety induction by the ingestion of certain natural compounds has been proven to be an interesting strategy. In this context, the present study had the following objectives: - Isolation of rucola, watercress and spinach, plum and tomato waste and cladodes of Opuntia ficus-indica extracts, rich in compounds with the potential to induce a prolonged feeling of satiety -
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Rodriguez, Montes de Oca Gustavo Alejandro. "Evaluation of dietary phytochemicals on sex differentiation and growth in Nile tilapia (Oreochromis niloticus)." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133358425.

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Silva, Inês Alexandra Marreiros. "Evaluation of chemotherapeutic potential of natural extracts using 3D models of colon cancer." Master's thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/10982.

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Dissertation to obtain master degree in Biotechnology<br>Recently there is a growing interest in cancer treatment through the use of natural compounds. In particular, phenolic compounds and monoterpenes found in fruits and vegetables are very attractive in the prevention and chemotherapy of various types of cancer. However, many promising compounds previously tested in in vitro cell models fail to demonstrate activity when evaluated in vivo. Therefore, there is an emerging need to develop more robust and reliable cellular models for pre-clinical evaluation of new chemotherapeutic agents. The
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Noutchang, Yves Roland Tchakounte. "Design and evaluation of fast dispersible tablets of lamivudine using selected natural superdisintegrants." University of the Western Cape, 2018. http://hdl.handle.net/11394/6781.

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Magister Pharmaceuticae - MPharm<br>Fast dispersible tablets (FDTs) are solid single-unit dosage forms that are placed in the mouth and allowed to disperse or dissolve in the saliva without the need of water. The basic approach to formulating FDTs consists of adding a superdisintegrant to a tablet formulation. These tablets offer both the advantages of conventional tablets and liquid dosage forms along with distinctive properties which include accurate dosing, ease of administration, quick onset of action, enhanced bioavailability, and increased patient adherence. FDTs have been found to
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Mbandezi, Yamkela. "Evaluation of cytotoxic activity of gold nanoparticles naturally synthesised from South African indigenous medicinal plant extracts." University of the Western Cape, 2018. http://hdl.handle.net/11394/6786.

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>Magister Scientiae - MSc<br>Nanotechnology has emerged as a promising field in the quest to address health conditions. Green nanotechnology is a fairly new branch of nanotechnology, which aims to produce and utilize nanomaterials in a way that is safe for living organisms and their environment. Plant extracts are increasingly used in the green synthesis of gold nanoparticles (AuNPs), which involves the reduction of sodium tetrachloroaurate (III) dehydrate by phytochemicals present in the plant extract. It is probable that the green synthesised AuNPs are more biocompatible than chemically synt
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ALFARANO, MICHELA. "Evaluation of the putative healthy effects of food phytochemicals: effect on blood antioxidant status, human cells and enzyme activities." Doctoral thesis, Università di Foggia, 2018. http://hdl.handle.net/11369/369483.

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Negli ultimi decenni, gli antiossidanti alimentari hanno ricevuto crescente attenzione, soprattutto in ambito biologico, medico e nutrizionale, in relazione alla loro capacità di contrastare lo stress ossidativo implicato nella patogenesi di diverse patologie cronico-degenerative. Numerosi sono i metodi attualmente disponibili in letteratura per valutare la capacità antiossidante (CA) in vitro degli alimenti. In tutti i casi si tratta di metodi semplici, rapidi e poco costosi che consentono di misurare la CA sia su composti puri che su matrici complesse, come alimenti e campioni biologici. Tut
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Omoruyi, Beauty Etinosa. "Evaluation of the efficacy of Carpobrotus edulis (L.) bolus leaf as a traditional treatment for the management of HIV/AIDS." Thesis, University of Fort Hare, 2014. http://hdl.handle.net/10353/744.

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The human immunodeficiency virus (HIV) is one of the most common and dreaded diseases of the 21th century. Today, the disease is still spreading with increasing incidence. “Since the beginning of the epidemic, almost 75 million people have been infected with the HIV virus and about 36 million people have died of HIV. Globally, 35.3 million [32.2–38.8 million] people were living with HIV at the end of 2012” (http://www.who.int/gho/hiv/en/). Several studies have been conducted on herbs under a multitude of ethnobotanical grounds. The use of medicinal plants for the management of HIV has become a
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Al-Marby, Adel [Verfasser], and Claus [Akademischer Betreuer] Jacob. "Nematicidal and antimicrobial evaluation of extracts, nanosized materials and fractions of selected plants and the identification of the bioactive phytochemicals / Adel Al-Marby ; Betreuer: Claus Jacob." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2017. http://d-nb.info/1142919730/34.

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Okpako, Larry Commander. "Investigation of selected Nigerian medicinal plants as a source of new antimalarial agents. Isolation of phytochemicals from some Nigerian medicinal plants using chromatographic techniques and their evaluation for antiplasmodial activity." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/6304.

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Malaria affects hundreds of millions of people worldwide and equally claims hundreds of thousands of lives each year. With the current spread of drug resistance to standard antimalarial drugs like chloroquine and the emergence of artemisinin-resistant parasites, new antimalarial drugs and formulations are urgently needed. An ethnobotanical survey was carried out in this study in search of novel compounds with promising antiplasmodial activity. Using the ethnobotanical approach, a total of 61 plant species from 59 genera distributed in 34 plant families were found to be used traditionally for
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"Phytochemical and biological evaluation of eucalyptus essential oil." Tese, BIBLIOTECA CENTRAL DA UFLA, 2006. http://bibtede.ufla.br/tede//tde_busca/arquivo.php?codArquivo=111.

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Chinsamy, Mayashree. "South African medicinal orchids : a pharmacological and phytochemical evaluation." Thesis, 2012. http://hdl.handle.net/10413/8689.

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The Orchidaceae makes up the largest and most diverse family of flowering plants. Orchids are popular, often expensive ornamentals, with a broad range of ethnobotanical applications. There is very limited documented information on South African medicinal orchid species; no formal pharmacopoeia outlining ethnobotanical uses; and ethnobotanical and distribution records are either scarce or inconsistent and plant populations are becoming gradually smaller. There have been significant developments in medicinal orchid research worldwide with medicinal use and corresponding pharmacological and phyto
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DIAS, TERESA. "Phytochemical study of Coreopsis tinctoria and evaluation of its antidiabetic properties." Doctoral thesis, 2011. http://hdl.handle.net/10451/4116.

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Tese de doutoramento, Farmácia (Química Farmacêutica e Terapêutica), Universidade de Lisboa, Faculdade de Farmácia, 2011<br>Coreopsis tinctoria Nutt. is a small aromatic annual and widely distributed plant that belongs to the Asteraceae family. Its use in traditional medicine has been described as early as the XVII century in China, where its decoction has been used for diarrhoea. Other medicinal properties have been added by North American Indians and include treatment of internal pains, bleeding, to strengthen blood and as an emetic. In Portugal, an infusion of the flowering tops has been de
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SAKSHI and SARIKA YADAV. "A COMPREHENSIVE REVIEW ON PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITIES OF OCIMUM SANCTUM." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/19862.

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Tulsi is often regarded as “the incomparable one”, “Elixir of life” and Queen of herbs”. Tulsi is being used for about a thousand years to support a healthy mind, body, and spirit. Tulsi is believed to have originated in northern central India but grows throughout the Indian subcontinent, Nepal, Bangladesh and much of Southeast Asia. Across different cultures, it is a symbol of purity. It is used to treat various types of diseases and disorders from ancient times. It has tremendous medicinal properties and is used to treat heart diseases, digestive issues, respiratory problems, men
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Ndou, Nzumbululo. "Evaluation of phytochemical constituents and mutagenic properties of Coccinia rehmanni And Jatropha zeyheri Plant Extracts." Diss., 2019. http://hdl.handle.net/11602/1312.

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MSc (Microbiology)<br>Department of Microbiology<br>Background: The medicinal value of plants lies in some chemical substances that produce a definite physiological action in the human body. The secondary metabolites help the plants to survive hash conditions and could be used by humans as supplements of their health, as foods additives or for medicinal purposes. This bioactive compounds are not always beneficial to human beings, and some of this plants bioactive compounds can be toxic or genotoxic to human cells. This study used several methods to evaluate of phytochemical constituents
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Van, Wyk Anna Susanna. "Phytochemical evaluation of Curtisia dentata (Burm.f.) C.A.Sm. stem bark and seasonal and geographical region variability." Thesis, 2020. http://hdl.handle.net/10500/27038.

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The stem bark of the protected tree species, Curtisia dentata (Burm. f.)C.A.Sm., is one of the most popular plant species harvested and traded at traditional medicine markets in South Africa. The overexploitation of C. dentata trees lead to a “Near Threatened” conservation status and the population trend is portrayed as “declining”. In the KwaZulu-Natal Province of South Africa, C. dentata is completely conservation dependent. This study is not based on drug discovery or toxicological studies, but on the concern that the stem bark of C. dentata trees are harvested, prepared into remedies and
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Murei, Arinao. "Synthesis, Characterization and Evaluation of Novel Treatment against Resistant Pathogenic Bacteria." Diss., 2018. http://hdl.handle.net/11602/1343.

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MSc (Microbiology)<br>Department of Microbiology<br>BACKGROUND: Antibiotic resistance amongst microbial pathogens has become a challenge over past decades, bringing about genuine and frequently deadly contaminations that can't be dealt with by ordinary means. This has led to a search on developing solutions to this problem by searching for new source of antimicrobial agents or chemically altering the existing ones. Traditional medicinal plants and nanoparticles are highly targeted as promising agents to address the challenge. Pyrenacantha grandiflora Baill from Icacenaceae family possess pharm
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Liu, Po-Jen, and 劉博仁. "Evaluation of Oxidative Stress, Inflammation, Apnea-Hypopnea Index and Quality of Life after Specific Phytochemical and Nutritional Supplement Therapy in Patients with Severe Obstructive Sleep Apnea." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/bpavn4.

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博士<br>中山醫學大學<br>營養學系博士班<br>106<br>Background:Obstructive sleep apnea(OSA)is an increasing sleeping disorder occurred owing to the repeatedly collapse and obstruction of the upper respiratory tract during the sleep. OSA is considered to be highly associated with the metabolic syndrome. Moreover, life style modification and body weight control should be taken into consideration beforehand while treating OSA patients with obesity. The purpose of this study is to examine how intervention of specific phytochemical-containing medical functional food, fish oil, vitamin C and Coenzyme Q10 affect patie
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Ndhlala, Ashwell Rungano. "Pharmacological, phytochemical and safety evaluaton of commercial herbal preparations common in South Africa." Thesis, 2009. http://hdl.handle.net/10413/729.

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Afonso, Nuno Filipe Costa. "Pastas enriched in Fucus vesiculosus: nutritional evaluation and biological properties." Master's thesis, 2019. http://hdl.handle.net/10773/30034.

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Despite their worldwide abundancy, algae are still considered an underexploited resource with a lot of interest in several industries, namely food and pharmaceuticals. Several reports comparing the diets of different countries, associate seaweed consumption with the oriental welfare and vitality contrarily to western societies. Within all three classes of edible seaweeds, those belonging to Phaeophyta have been receiving a lot of attention particularly due to their abundance in complex polysaccharides, phlorotannins, fucoxanthin and iodine. This work reports the nutritional composition
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Mulaudzi, Rofhiwa Bridget. "Pharmacological evaluation of medicinal plants used by Venda people against venereal and related diseases." Thesis, 2012. http://hdl.handle.net/10413/8663.

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Venereal diseases (VDs) are infections that are mainly transmitted through sexual intercourse and amongst these are gonorrhoea, syphilis, chlamydia and trichomoniasis. Gonorrhoea is the most commonly known VD and the widest spread contagious infection in the world. Out of 448 million cases of curable venereal infections, gonorrhoea represents 88 million cases and the rest are syphilis, chlamydia and trichomoniasis. Gonorrhoea has recently been rated as in the emergent multidrug resistance phase. Venereal diseases are amongst the major diseases ravaging many rural communities. People infected w
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