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1

Tan, K. W., A. Scheepens, Y. Li, and J. Paxton. "DESIGNED PHYTOCHEMICAL SYNERGIES FOR FUNCTIONAL FOODS OF THE FUTURE - ABC TRANSPORTER-MEDIATED PHYTOCHEMICAL BIOAVAILABILITY." Acta Horticulturae, no. 939 (November 2012): 137–52. http://dx.doi.org/10.17660/actahortic.2012.939.17.

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2

Khaleel Basha, Sabjan, Kasivelu Govindaraju, Ramar Manikandan, Jong Seog Ahn, Eun Young Bae, and Ganesan Singaravelu. "Phytochemical mediated gold nanoparticles and their PTP 1B inhibitory activity." Colloids and Surfaces B: Biointerfaces 75, no. 2 (2010): 405–9. http://dx.doi.org/10.1016/j.colsurfb.2009.09.008.

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3

Alharbi, Fawzeeh Nayif, Zulfa Mohamed Abaker, and Suzan Zein Alabdeen Makawi. "Phytochemical Substances—Mediated Synthesis of Zinc Oxide Nanoparticles (ZnO NPS)." Inorganics 11, no. 8 (2023): 328. http://dx.doi.org/10.3390/inorganics11080328.

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Artemisia absinthium (A. absinthium) leaf extract was successfully used to create zinc oxide nanoparticles (ZnO NPs), and their properties were investigated via several techniques, including X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), Fourier transform infrared (FTIR), and ultraviolet–visible spectroscopy (UV–Vis spectroscopy). SEM analysis confirmed the spherical and elliptical shapes of the particles. Three different zinc peaks were observed via EDX at the energies of 1, 8.7, and 9.8 keV, together with a single oxygen peak at 0.5 keV. The XRD a
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4

Dong, Fangcong, Andrew J. Annalora, Iain A. Murray, et al. "Phytochemical-Mediated Ah Receptor Activity Is Dependent on Dietary Context." Nutrients 17, no. 5 (2025): 876. https://doi.org/10.3390/nu17050876.

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Background/Objective: The aryl hydrocarbon receptor (AHR) is an important mediator of intestinal homeostasis. The AHR senses certain classes of phytochemicals, including many flavonoids and tryptophan metabolites generated in the intestinal tract. Several in vitro studies demonstrate the presence of AHR ligands in numerous plants commonly consumed by humans. However, it has not been established that these foods can activate the AHR in vivo. The aim of this study was to evaluate how phytochemicals in foods can lead to AHR activation in vivo through modulating CYP1A1 activity. Methods: Freeze-dr
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5

Prachi, Desale Safid Halim Khan* Vivek Waghere. "A Fruit Review on Marvelous Milberry With Its Nutrition, Pharmacological Activity and Formulation." International Journal of Scientific Research and Technology 2, no. 5 (2025): 472–85. https://doi.org/10.5281/zenodo.15469153.

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The mulberry (Morius alba), which is a member of the Moraceae family, is a symbol of fruit coldness. It comes in three different colours: white, red, and black. Its fruits have a variety of therapeutic benefits, including antioxidant, anticancer, antidiabetic, hepatoprotective, neuroprotective, anti-inflammatory, anti-obesity, hypolipidemic, and antibacterial qualities. Their nutritional makeup and phytochemical-mediated biological pathways further bolster their significance. Although there are many different species of mulberries, the review focusses on Morus alba, Morus nigra, and Morus rubr
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Prachi, Desale Safid Halim Khan* Vivek Waghere. "A Fruit Review on Marvelous Milberry With Its Nutrition, Pharmacological Activity and Formulation." International Journal of Scientific Research and Technology 2, no. 5 (2025): 472–85. https://doi.org/10.5281/zenodo.15469183.

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The mulberry (Morius alba), which is a member of the Moraceae family, is a symbol of fruit coldness. It comes in three different colours: white, red, and black. Its fruits have a variety of therapeutic benefits, including antioxidant, anticancer, antidiabetic, hepatoprotective, neuroprotective, anti-inflammatory, anti-obesity, hypolipidemic, and antibacterial qualities. Their nutritional makeup and phytochemical-mediated biological pathways further bolster their significance. Although there are many different species of mulberries, the review focusses on Morus alba, Morus nigra, and Morus rubr
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7

T, Thilagavathi, Arvindganth R, Vidhya D, and Dhivya R. "PRELIMINARY PHYTOCHEMICAL SCREENING OF DIFFERENT SOLVENT MEDIATED MEDICINAL PLANT EXTRACTS EVALUATED." International Research Journal of Pharmacy 6, no. 4 (2015): 246–48. http://dx.doi.org/10.7897/2230-8407.06455.

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8

Cao, Hang, Xuejun Li, Feiyifan Wang, Yueqi Zhang, Yi Xiong, and Qi Yang. "Phytochemical-Mediated Glioma Targeted Treatment: Drug Resistance and Novel Delivery Systems." Current Medicinal Chemistry 27, no. 4 (2020): 599–629. http://dx.doi.org/10.2174/0929867326666190809221332.

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Glioma, especially its most malignant type, Glioblastoma (GBM), is the most common and the most aggressive malignant tumour in the central nervous system. Currently, we have no specific therapies that can significantly improve its dismal prognosis. Recent studies have reported promising in vitro experimental results of several novel glioma-targeting drugs; these studies are encouraging to both researchers and patients. However, clinical trials have revealed that novel compounds that focus on a single, clear glioma genetic alteration may not achieve a satisfactory outcome or have side effects t
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9

Cukrov, Marin, Velemir Ninkovic, Luna Maslov Bandić, et al. "Silicon-Mediated Modulation of Olive Leaf Phytochemistry: Genotype-Specific and Stress-Dependent Responses." Plants 14, no. 9 (2025): 1282. https://doi.org/10.3390/plants14091282.

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Secondary metabolites in olive (Olea europaea L.) leaves constitute a complex framework wherein phenylpropanoids, terpenoids, and secoiridoids in particular, serve as major contributors to olive plant resilience. Silicon (Si) stands as a mediator of defense mechanisms in plants, enhancing their protective responses and adaptability. A field trial on one-year-old plantlets of two metabolically distinct olive genotypes was conducted to investigate the effects of foliar-applied Si on the phytochemical profiles of locally treated leaves. Silicon’s systemic effects in juvenile leaves were also appr
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10

Richards, Lora A., Lee A. Dyer, Matthew L. Forister, et al. "Phytochemical diversity drives plant–insect community diversity." Proceedings of the National Academy of Sciences 112, no. 35 (2015): 10973–78. http://dx.doi.org/10.1073/pnas.1504977112.

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What are the ecological causes and consequences of variation in phytochemical diversity within and between plant taxa? Despite decades of natural products discovery by organic chemists and research by chemical ecologists, our understanding of phytochemically mediated ecological processes in natural communities has been restricted to studies of either broad classes of compounds or a small number of well-characterized molecules. Until now, no studies have assessed the ecological causes or consequences of rigorously quantified phytochemical diversity across taxa in natural systems. Consequently,
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11

Llauradó, Gabriel, Humberto J. Morris, Yamila Lebeque, et al. "Phytochemical screening and effects on cell-mediated immune response ofPleurotusfruiting bodies powder." Food and Agricultural Immunology 24, no. 3 (2013): 295–304. http://dx.doi.org/10.1080/09540105.2012.686988.

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12

Kulka, Marianna. "Phytochemical Effects on FcepsilonRI and MrgprX2-mediated Activation of Human Mast Cells." Journal of Immunology 206, no. 1_Supplement (2021): 23.07. http://dx.doi.org/10.4049/jimmunol.206.supp.23.07.

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Abstract Phytochemicals and herbal extracts are currently used in food supplements as a means of preventing and treating disease. Although phytochemicals have been studied for their potentially beneficial effects on coronary heart disease and their ability to prevent atherosclerosis, certain cancers and inflammatory disease, very little attention has been focused on the potential health benefits of phytochemicals in atopic disease. Mast cells synthesize and store several proinflammatory mediators and are centrally important in atopic diseases such as asthma. Our team has been characterizing th
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13

Javed, Rabia, Shumaila Ijaz, Hajra Hameed, et al. "Phytochemical-Mediated Biosynthesis of Silver Nanoparticles from Strobilanthes glutinosus: Exploring Biological Applications." Micromachines 14, no. 7 (2023): 1372. http://dx.doi.org/10.3390/mi14071372.

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The application of green synthesis for silver nanoparticles in nanomedicine has experienced significant growth. Strobilanthes glutinosus, a plant primarily located in the Himalayas, remains largely unexplored. Considering the biomedical value of S. glutinosus, phytochemicals from this plant were used for the biosynthesis of silver nanoparticles. Silver nanoparticles were synthesized from aqueous extract of root and leaves of Strobilanthes glutinosus. The synthesized silver nanoparticles were characterized using UV–Vis spectrophotometry, Fourier-transform infrared spectroscopy, transmission ele
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Soteriou, G. A., M. C. Kyriacou, A. S. Siomos, and D. Gerasopoulos. "ROOTSTOCK-MEDIATED EFFECTS ON WATERMELON RIPENING BEHAVIOR AND FRUIT PHYSICOCHEMICAL AND PHYTOCHEMICAL COMPOSITION." Acta Horticulturae, no. 1079 (March 2015): 707–14. http://dx.doi.org/10.17660/actahortic.2015.1079.97.

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15

Vasudevan, Prathibha, Viji Vidyadharan, Sanu Mathew Simon, and Unnikrishnan N. V. "Phytochemical mediated synthesis of ZnO:Dy3+ nanophosphors: Judd–Ofelt analysis, structural and spectroscopic properties." Journal of Science: Advanced Materials and Devices 5, no. 2 (2020): 242–49. http://dx.doi.org/10.1016/j.jsamd.2020.05.001.

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16

Paredes-Gonzalez, Ximena, Francisco Fuentes, Sundrina Jeffery, et al. "Induction of NRF2-mediated gene expression by dietary phytochemical flavones apigenin and luteolin." Biopharmaceutics & Drug Disposition 36, no. 7 (2015): 440–51. http://dx.doi.org/10.1002/bdd.1956.

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17

Elizabeth Ogunbamowo, Oyebola, Ali El-Rayyes, Mohamed Hefnawy, et al. "Optical and phytochemical detection of decayed food items using yeast mediated silver nanoparticle." Bulletin of the Chemical Society of Ethiopia 39, no. 5 (2025): 921–36. https://doi.org/10.4314/bcse.v39i5.9.

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This study emphasized the use of silver nanoparticle (AgNPs) produced from yeast isolate to detect decayed food items like tomatoes, doughnut, and bread. The synthesized AgNPs was monitored via its surface plasmon resonance (SPR) reading with UV-Visible spectrophotometer and later characterized with Fourier transform infrared spectroscopy (FT-IR), X-ray diffractometer (XRD), scanning electron microscope (SEM), and energy dispersed x-ray (EDX). The UV-Visible reading were observed between wavelength of 350 - 450 nm, while XRD diffraction showed three distinct peaks at 38.08°, 44.28° and 64.51°
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18

Sivakumar, Surya, Boobal Rangaswamy, Lathika Shanmugam, and Kamalesh Marudhachalam. "Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity." Next Nanotechnology 8 (2025): 100210. https://doi.org/10.1016/j.nxnano.2025.100210.

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19

Shahrtash, Maryam, and Shawn P. Brown. "A Path Forward: Promoting Microbial-Based Methods in the Control of Invasive Plant Species." Plants 10, no. 5 (2021): 943. http://dx.doi.org/10.3390/plants10050943.

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In this review, we discuss the unrealized potential of incorporating plant–microbe and microbe–microbe interactions into invasive plant management strategies. While the development of this as a viable strategy is in its infancy, we argue that incorporation of microbial components into management plans should be a priority and has great potential for diversifying sustainable control options. We advocate for increased research into microbial-mediated phytochemical production, microbial controls to reduce the competitiveness of invasive plants, microbial-mediated increases of herbicidal tolerance
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20

Swaminathan, Chandrasekaran. "PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL AND ANTIOXIDANT PROPERTIES OF INDIGOFERA TINCTORIA L." Asian Journal of Pharmaceutical and Clinical Research 11, no. 6 (2018): 136. http://dx.doi.org/10.22159/ajpcr.2018.v11i6.20060.

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Objective: The present study was designed to evaluate the phytochemical composition and antibacterial and antioxidant potential of methanolic leaf and root extracts of Indigofera tinctoria L.Methods: Phytochemical analysis was done using standard methods. The methanolic leaf and root extracts of the plant were tested against Staphylococcus aureus, Enterococcus faecalis, Klebsiella pneumoniae, Enterobacter aerogenes, and Salmonella paratyphi B by cup-plate agar diffusion method. The free radical scavenging activities of the methanol extracts of leaves and roots were evaluated by 2,2-diphenyl-1-
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21

Alhassan, Aisha Muhammad, Nafisah Bisallah Lawal, and Suleiman Danladi. "Analgesic and anti-inflammatory studies of the methanol extract of Globimetula braunii (Loranthaceae) growing on Terminalia catappa Linn (Combretaceae)." Journal of Pharmacy & Bioresources 20, no. 2 (2023): 74–80. http://dx.doi.org/10.4314/jpb.v20i2.2.

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This study was carried out to investigate the phytochemical constituents, analgesic and anti-inflammatory activity of methanol stem extract of Globimetula braunii. Preliminary phytochemical screening was done using standard protocols, median lethal dose (LD50) was determined by Lorke’s method. Analgesic and anti-inflammatory activities of extract were determined using acetic acid induced writhing and hot-plate model and the carrageenan-induced rat's paw edema model respectively at graded doses of 1000 mg/kg, 500 mg/kg and 250mg/kg. The phytochemical screening revealed the presence of flavonoid
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22

Yang, Jinsong, Xiaohong Wu, Haogang Yu, Xinbiao Liao, and Lisong Teng. "NMDA Receptor-Mediated Neuroprotective Effect of theScutellaria baicalensisGeorgi Extract on the Excitotoxic Neuronal Cell Death in Primary Rat Cortical Cell Cultures." Scientific World Journal 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/459549.

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The objective of the current research work was to evaluate the neuroprotective effect of the ethanol extract ofScutellaria baicalensis(S.B.) on the excitotoxic neuronal cell death in primary rat cortical cell cultures. The inhibitory effects of the extract were qualitatively and quantitatively estimated by phase-contrast microscopy and lactate dehydrogenase (LDH) assays. The extract exhibited a potent and dose-dependent inhibition of the glutamate-induced excitotoxicity in the culture media. Further, using radioligand binding assays, it was observed that the inhibitory effect of the extract wa
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23

Wong, Fai-Chu, Siok-Thing Tan, and Tsun-Thai Chai. "Phytochemical-mediated Protein Expression Profiling and the Potential Applications in Therapeutic Drug Target Identifications." Critical Reviews in Food Science and Nutrition 56, sup1 (2015): S162—S170. http://dx.doi.org/10.1080/10408398.2015.1045967.

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24

Shahlehi, Syahirah, Aziemah Azizi, Asrin Tengah, Siti Nornadhirah Amdani, and Mark I. R. Petalcorin. "Anti-hypertensive vasodilatory action of Gynura procumbens mediated by kaempferol 3-O-rutinoside." F1000Research 9 (October 12, 2020): 1226. http://dx.doi.org/10.12688/f1000research.25613.1.

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Introduction: Gynura procumbens (GP), otherwise known as longevity spinach or “Sambung Nyawa” in Malay, is an evergreen herb found in Africa and Southeast Asian countries (including Brunei) used traditionally to treat various diseases such as fever, diabetes and hypertension. We examined GP’s vasodilatory action to determine its possible role via the cholinergic-mediated pathway. Methods: GP leaves were prepared by filtration and evaporation to obtain the aqueous (AEGP) and methanol (MEGP) extracts followed by screening for phytochemical constituents. The total phenol, total flavonoid and flav
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Suhartono, Suhartono, Cut Soraya, and Putri Shabira. "Antibiofilm activity of neem leaf (Azadirachta indica A. Juss) ethanolic extracts against Enterococcus faecalis in vitro." Dental Journal (Majalah Kedokteran Gigi) 56, no. 2 (2023): 98–103. http://dx.doi.org/10.20473/j.djmkg.v56.i2.p98-103.

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Background: Enterococcus faecalis commonly infects root canals by forming a biofilm. Extracts from neem leaves (Azadirachta indica A. Juss) have been shown to have antibacterial properties, indicating their potential in preventing or treating biofilm formation caused by bacteria. Purpose: This study aims to investigate the phytochemical compounds present in neem leaves (Azadirachta indica A. Juss) and establish the concentration of ethanol-based neem leaf extract that can effectively inhibit the in vitro growth of Enterococcus faecalis biofilm. Methods: This study employed the maceration techn
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26

Al-Malki, Wedad F., and Njud S. Alharbi. "Ficus Plant-Mediated Silver Nanoparticles: Synthesis, Optimization, Characterization, and Biomedical Applications." Journal of Pure and Applied Microbiology 19, no. 1 (2025): 74–99. https://doi.org/10.22207/jpam.19.1.58.

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Silver nanoparticles (AgNPs) are known for their exceptional physicochemical characteristics, including remarkable stability and conductivity, catalytic activity, and antibacterial capabilities. The emerging approach of plant-mediated synthesis of AgNPs is eco-friendly, non-hazardous, sustainable in biomedical applications, and highly cost-effective. Its non-toxicity and rapidity instill confidence in its potential, making it a secure choice. Plant-derived AgNPs combine nanotechnology features with the therapeutic potential of plant bioactive compounds, offering significant potential for medic
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27

Rocha, Jamira Dias, Marilia Elias Gallon, Abel Vieira de Melo Bisneto, et al. "Phytochemical Composition and Protective Effect of Vernonanthura polyanthes Leaf against In Vivo Doxorubicin-Mediated Toxicity." Molecules 27, no. 8 (2022): 2553. http://dx.doi.org/10.3390/molecules27082553.

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Vernonanthura polyanthes (Spreng.) A.J. Vega & Dematt. (syn.: Vernonia polyanthes Less) is popularly known as “assa-peixe” and its leaves are used in folk medicine mainly to treat respiratory diseases. In this study, we evaluated the cytogenotoxic and anticytogenotoxic potential of the V. polyanthes leaf aqueous extract (VpLAE) and its n-butanol fraction (n-BF) in the presence or absence of doxorubicin (DXR) (pre-, co-, and post-treatments) on a murine model for 24 h or 120 h. The micronucleus test (MN) and the comet assay were used to assess the cytogenotoxic and anticytogenotoxic potenti
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28

Tilghman, Syreeta L., Lyndsay V. Rhodes, Melyssa R. Bratton, et al. "Phytoalexins, miRNAs and Breast Cancer: A Review of Phytochemical-mediated miRNA Regulation in Breast Cancer." Journal of Health Care for the Poor and Underserved 24, no. 1A (2013): 36–46. http://dx.doi.org/10.1353/hpu.2013.0036.

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29

Sana, Siva Sankar, Ramakrishna Vadde, Sai Kumar Arla, et al. "Phytochemical-Mediated Synthesis of Nanozinc Oxide Particles and Its Antibacterial, Photocatalytic Degradation of Methylene Blue." Journal of Nanomaterials 2023 (April 19, 2023): 1–8. http://dx.doi.org/10.1155/2023/8767080.

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Using aqueous leaf extract of Givotia moluccana, we offer a bioreduction technique for phytochemical-mediated production of nanozinc oxide (N-ZnOPs) particles. Phytochemicals such as polyphenols, flavonoids, and proteins were discovered in the water extract. UV–visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (X-RD), and transmission electron microscopy (TEM) are as follows. The UV–visible spectra of synthesized N-ZnOPs revealed absorption peaks at 370 nm. The crystalline nature of ZnO was confirmed by X-RD pattern analyses. Furthermore, TEM pic
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Tungmunnithum, Duangjai, Samantha Drouet, Laurine Garros, and Christophe Hano. "Differential Flavonoid and Other Phenolic Accumulations and Antioxidant Activities of Nymphaea lotus L. Populations throughout Thailand." Molecules 27, no. 11 (2022): 3590. http://dx.doi.org/10.3390/molecules27113590.

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Nymphaea lotus L. is a potential plant in the Nymphaeaceae family that is well-recognized as an economic and traditional medicinal plant in Thailand and other countries. Its pharmacological and medicinal effects have been confirmed. However, there is no study going deeper into the population level to examine the phytochemical variation and biological activity of each population that benefits phytopharmaceutical and medical applications using this plant as raw material. This study was intensely conducted to complete this important research gap to investigate the flavonoid profiles from its flor
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Ethiraj, Sumathi, and Vandana Sridar. "PHYTOCHEMICAL SCREENING, ANTIOXIDANT ACTIVITY AND EXTRACTION OF ACTIVE COMPOUND (ANONAINE) FROM FRUIT PEEL EXTRACT OF ANNONA RETICULATA L." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 372. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.27838.

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Objective: The main objective of this study was to analyze the phytochemical constituents, total phenol, total flavonoid, alkaloid content, in vitro antioxidant activity and high-performance liquid chromatography (HPLC) analysis of anonaine compound from the fruit peel extract of Annona reticulata L.Methods: Preliminary phytochemical analysis for alkaloids, cardiac glycosides, flavonoids, glycosides, phenols, saponins, steroids, tannins, and terpenoids was studied. Quantitative phytochemical analysis for total phenolics, total flavonoids and alkaloids was determined according to standard proto
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32

Trang, Tran Thi Thu, Lai Thi Ngoc Ha, Doan Thi Thuy Ai, Nguyen Thi Hien, Nguyen Thi Thu Tram, and Vu Thi Huyen. "Phytochemical Analysis and Antioxidant and Alpha-glucosidase Inhibitory Activities of the Stem Bark of Dialium cochinchinense Pierre." Vietnam Journal of Agricultural Sciences 5, no. 1 (2022): 1375–88. http://dx.doi.org/10.31817/vjas.2022.5.1.06.

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The purpose of this study was to determine the phytochemical compositions and to evaluate the biological activity of the stem bark of Dialium cochinchinense. The phytochemical analysis showed the presence of steroids, terpenoids, anthraquinones, saponins, and phenolics in the stem bark of D. cochinchinense. The optimal extraction conditions were 70% ethanol at 30°C for 40min with a material/solvent ratio of 1/20. Under the optimal conditions, the corresponding predicted response value for the total phenolic content was 100.80 ± 0.40 mg GAE/g DW. The evaluation of antioxidant activity indicated
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Hasan, Nor' Aishah, Nurul Natasha Wazir, Nurhamimah Zainal-Abidin, et al. "Antibacterial and Antiviral Potential of Zirconium Oxide Nanoparticle using Extract of Chloranthus erectus Leaf." Asian Journal of Chemistry 36, no. 7 (2024): 1705–12. http://dx.doi.org/10.14233/ajchem.2024.31775.

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Zirconium oxide nanoparticles (ZrO2 NPs) were synthesized with an effective capping agent using aqueous extract of Chlorentus erectus at the optimized conditions. The aqueous leaf extract contained phytochemical compounds that could regulate the size and shape of the nanoparticles. The average size of C. erectus-ZrO2 NPs crystallite was 10.42 nm, which was determined based on Scherrer Debye’s equation. The finding indicated the effectiveness of the phytochemical compounds to diminish the agglomeration of the particles. The C. erectus mediated ZrO2 NPs were in spherical clusters when observed t
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Bettini, Priscilla Paola, Martina Imbesi, Patrizia Bogani, et al. "Effects of the Agrobacterium rhizogenes rolC Gene Insertion on Secondary Metabolites Profile and In Vitro Biological Activity of Acmella oleracea (L.) R.K. Jansen." Plants 14, no. 9 (2025): 1373. https://doi.org/10.3390/plants14091373.

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This study investigates the transformation of Acmella oleracea with the Agrobacterium rhizogenes rolC gene and evaluates its impact on phytochemical composition and biological activity. A total of 480 plant nodes were subjected to Agrobacterium−mediated transformation, leading to the regeneration of 35 putative transgenic plants. Molecular analysis confirmed the presence of the rolC transgene in 17 clones, of which four (C123, C127, C129, and C132) exhibited rolC mRNA expression. Phytochemical profiling of hydroalcoholic extracts of aerial parts (AP) and roots (R) revealed significant differen
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Murakami, Tadayuki, Keiichi Honda, Tadanobu Nakayama, and Nanao Hayashi. "Phytochemical-mediated differential acceptance of four rutaceous plants by a swallowtail butterfly, Papilio polytes (Lepidoptera: Papilionidae)." Applied Entomology and Zoology 38, no. 1 (2003): 37–43. http://dx.doi.org/10.1303/aez.2003.37.

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Park, Ye-Jin, Dong Wook Choi, Sang Woo Cho, Jaeseok Han, Siyoung Yang, and Cheol Yong Choi. "Stress Granule Formation Attenuates RACK1-Mediated Apoptotic Cell Death Induced by Morusin." International Journal of Molecular Sciences 21, no. 15 (2020): 5360. http://dx.doi.org/10.3390/ijms21155360.

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Stress granules are membraneless organelles composed of numerous components including ribonucleoproteins. The stress granules are characterized by a dynamic complex assembly in response to various environmental stressors, which has been implicated in the coordinated regulation of diverse biological pathways, to exert a protective role against stress-induced cell death. Here, we show that stress granule formation is induced by morusin, a novel phytochemical displaying antitumor capacity through barely known mechanisms. Morusin-mediated induction of stress granules requires activation of protein
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Nivetha, S., Dr K. Sathiyamoorthi, and Dr S. DarlinQuine. "GREEN SYNTHESIS, CHRACTERISATION AND ANTIBCTERIAL ACTIVITIES OF TUNGSTEN, TIN AND LEAD NANOPARTICLES BYCUCURBITA MAXIMA (PUMPKIN) FLOWER EXTRACT." YMER Digital 21, no. 02 (2022): 654–70. http://dx.doi.org/10.37896/ymer21.02/62.

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In this paper, a green synthetic route was developed to synthesize tungsten, tin and lead nanoparticles mediated by the Cucurbita maxima flower extract, Cucurbita is monoecious (unisexual flowers, with male and female on the same plant), bearing solitary actinomorphic flowers (10-20 cm across) that are open for a single day Cucurbita maxima was a traditional vegetable food for south Indian. The flower of Cucurbita maxima aqueous extract is analyzed for the phytochemical constituent. The synthesized nanoparticles are characterized by UV, FTIR, XRD and SEM with EDS. The synthesized three nanopar
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Sharma, Garima, Naveen Sharma, Bao Trong Nguyen, et al. "Protective Potential of Ginkgo biloba Against an ADHD-like Condition." Current Molecular Pharmacology 14, no. 2 (2020): 200–209. http://dx.doi.org/10.2174/1874467213666200424152454.

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Background: Attention deficit hyperactivity disorder (ADHD) is a psychiatric disorder commonly found in children, which is recognized by hyperactivity and aggressive behavior. It is known that the pathophysiology of ADHD is associated with neurobiological dysfunction. Although psychostimulants are recognized as the therapeutic drugs of choice for ADHD patients, the side effects might be of great concern. Ginkgo biloba is a promising herbal complementary supplement that may modulate the neuronal system in an ADHD-like condition. The beneficial effect of Ginkgo biloba on ADHD-like symptoms may b
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Al-Qrimli, Ayah F. "The Gastroprotective Effects of Papaya Seed Crude Extract on Aspirin Induced Gastric Ulcer in Mice." Saudi Journal of Medical and Pharmaceutical Sciences 11, no. 04 (2025): 339–44. https://doi.org/10.36348/sjmps.2025.v11i04.016.

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The seeds of carica papaya fruit have been studied for its gastroprotective action on patients with gastric ulcer due to its rich phytochemical constituents that have strong antioxidants and anti-inflammatory activity. The seeds of the newly cultivated in Iraq c.papaya plant were collected and extracted via Soxhlet apparatus using 70% aqueous ethanol. The ethanolic extract was phytochemically investigated to show the presence of flavonoids, phenolic compounds, alkaloids and saponins. Our in-vitro study model of the gastro protective action of the seed extract used aspirin for the induction of
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Suciu, Felicia, Dragos Paul Mihai, Anca Ungurianu, et al. "Investigation of Anticonvulsant Potential of Morus alba, Angelica archangelica, Valeriana officinalis, and Passiflora incarnata Extracts: In Vivo and In Silico Studies." International Journal of Molecular Sciences 26, no. 13 (2025): 6426. https://doi.org/10.3390/ijms26136426.

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The current study evaluated the anticonvulsant properties of ethanolic extracts from Morus alba, Angelica archangelica, Passiflora incarnata, and Valeriana officinalis using integrated phytochemical, in vivo, biochemical, and computational approaches. Phytochemical analysis by UHPLC-HRMS/MS revealed the presence of various bioactive compounds, notably flavonoids such as isorhamnetin, quercetin, and kaempferol. In an electroshock-induced seizure model, Morus alba extract (MAE, 100 mg/kg) demonstrated significant anticonvulsant effects, reducing both seizure duration and incidence, likely mediat
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Jyothi, K. R., K. R. Bhagya, G. P. Darshan, et al. "Phytochemical mediated synthesis of praseodymium doped beta-eucryptite nanophosphor for ultraviolet stimulated fluorescence based unclonable security applications." Inorganic Chemistry Communications 130 (August 2021): 108671. http://dx.doi.org/10.1016/j.inoche.2021.108671.

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42

Qahtan, Ahmed A., Mohammad Faisal, Abdulrahman A. Alatar, and Eslam M. Abdel-Salam. "Callus-Mediated High-Frequency Plant Regeneration, Phytochemical Profiling, Antioxidant Activity and Genetic Stability in Ruta chalepensis L." Plants 11, no. 12 (2022): 1614. http://dx.doi.org/10.3390/plants11121614.

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Efficient methods for callus induction and the high-frequency plant regeneration of Ruta chalepensis L. were established, and the phytochemical potential and antioxidant activity of a donor plant, ex-vitro-established micropropagated plants, and callus were also studied. Yellowish-green callus was induced with a frequency of 97.8% from internode shoot segments of the donor plant growing in soil in the botanical garden cultured on Murashige and Skoog (MS) medium containing 10 μM 2,4-D (2,4-dichlorophenoxyacetic acid) and 1 μM BA (6-benzyladenine). Adventitious shoots were regenerated from the y
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43

Venkataramana, B., S. Siva Sankar, A. Saikumar, and B. Vijaya Kumar Naidu. "Phytochemical Mediated Synthesis of Silver Nanoparticles using Musa paradisiaca Peduncle Latex and Its Photocatalytic and Antimicrobial Activity." Volume 4,Issue 5,2018 4, no. 5 (2018): 503–7. http://dx.doi.org/10.30799/jnst.151.18040511.

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In the present work, green synthesis of silver nanoparticles (AgNPs) using a natural phytochemical agent has been described. The aqueous latex from Musa paradisiaca peduncle has been utilized as reducing as well as stabilizing agent. The formation of AgNPs was optimized by varying latex and AgNO3 concentrations and finally reaction time. Ultraviolet-visible spectroscopic analysis showed the surface plasmon resonance peak between 350 and 450 nm confirms the formation of silver nanoparticles. X-ray powder diffraction analysis revealed the crystalline nature of AgNPs, Fourier transform infrared s
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Heo, Jae-Rim, Geum-A. Lee, Gyu-Sik Kim, Kyung-A. Hwang, and Kyung-Chul Choi. "Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells." Phytomedicine 39 (January 2018): 100–110. http://dx.doi.org/10.1016/j.phymed.2017.12.006.

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Paul, Santanu, Subhendu Chakrabarty, Suvranil Ghosh, et al. "Targeting cellular microtubule by phytochemical apocynin exhibits autophagy-mediated apoptosis to inhibit lung carcinoma progression and tumorigenesis." Phytomedicine 67 (February 2020): 153152. http://dx.doi.org/10.1016/j.phymed.2019.153152.

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Khalifa, Fares. "Antioxidant Mediated Defense Role of the Dietary Phytochemical Ferulic Acid, against Carbon Tetrachloride (CCl4) Induced Toxic Hepatitis." Advances in Research 1, no. 1 (2013): 11–22. http://dx.doi.org/10.9734/air/2013/6169.

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Treyer, Andrea, Jakob K. Reinhardt, Daniela Elisabeth Eigenmann, Mouhssin Oufir, and Matthias Hamburger. "Phytochemical Comparison of Medicinal Cannabis Extracts and Study of Their CYP-Mediated Interactions with Coumarinic Oral Anticoagulants." Medical Cannabis and Cannabinoids 6, no. 1 (2023): 21–31. http://dx.doi.org/10.1159/000528465.

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Introduction: Treatment with cannabis extracts for a variety of diseases has gained popularity. However, differences in herb-drug interaction potential of extracts from different plant sources are poorly understood. In this study, we provide a characterization of cannabis extracts prepared from four cannabis chemotypes and an in vitro assessment of their Cytochrome P450 (CYP)-mediated herb-drug interaction profiles. Methods: Plant extracts were either commercially obtained or prepared using ethanol as solvent, followed by overnight decarboxylation in a reflux condenser system. The extracts wer
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Li, Shinan, Pham Ngoc Khoi, Hong Yin та ін. "Sulforaphane Suppresses the Nicotine-Induced Expression of the Matrix Metalloproteinase-9 via Inhibiting ROS-Mediated AP-1 and NF-κB Signaling in Human Gastric Cancer Cells". International Journal of Molecular Sciences 23, № 9 (2022): 5172. http://dx.doi.org/10.3390/ijms23095172.

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Sulforaphane, a natural phytochemical compound found in various cruciferous vegetables, has been discovered to present anti-cancer properties. Matrix metalloproteinase-9 (MMP-9) plays a crucial role in gastric cancer metastasis. However, the role of sulforaphane in MMP-9 expression in gastric cancer is not yet defined. Nicotine, a psychoactive alkaloid found in tobacco, is associated with the development of gastric cancer. Here, we found that sulforaphane suppresses the nicotine-mediated induction of MMP-9 in human gastric cancer cells. We discovered that reactive oxygen species (ROS) and MAPK
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Vashisht, Sushma, Manish Pal Singh, and Viney Chawla. "In-vitro Antioxidant and Antibacterial Activity of Methanolic Extract of Shorea robusta Gaertn. F. Resin." International Journal of Pharmaceutical and Phytopharmacological Research 6, no. 4 (2016): 68. http://dx.doi.org/10.24896/eijppr.2016641.

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The methanolic extract of the resin of Shorea robusta was subjected to investigate its antioxidant and antibacterial properties its utility in free radical mediated diseases including diabetic, cardiovascular, cancer etc. The methanol extract of the resin was tested for antioxidant activity using scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazil) radical method, reducing power by FeCl3 and antibacterial activity against gram positive and gram negative bacteria using disc diffusion method. The phytochemical screening considered the presence of triterpenoids, tannins and flavoniods. Ove
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Neha Biradar and Himanshi Deshmukh. "Study of Datura stramonium metallic nanoparticles showing anti-cancer and anti-microbial properties: A review." International Journal of Life Science Research Archive 8, no. 1 (2025): 001–9. https://doi.org/10.53771/ijlsra.2025.8.1.0077.

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Datura stramonium metallic nanoparticles show anti-cancer and anti-microbial propensities: in vitro precedes in vivo rationale. Gold, silver, copper nanoparticles and zinc oxide nanoparticles were prepared using D. stramonium extracts by green synthesis methods owing to its vast phytochemical profile with major tropane alkaloids content. The nanoparticles showed greater stability and biopotency as revealed by their higher cytotoxic potential against a number of cancer cell lines as well as antimicrobial activity against Gram-positive and Gram-negative bacteria. This research shed more light on
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